Document Document Title
US10450823B1 Flange adapter
The flange adapter attaches to the flange of a housing such as a bowl. The flow line attaches at the flange of the housing. The flange adapter attaches at the flange of the bowl to enable attachment of flow lines of multiple sizes to the bowl. The flange adapter includes an attachment body that secures to the bowl and an attachment neck that is raised above the attachment body. The flange adapter provides a first set of attachment apertures for securing the flange adapter to the housing and a second set of attachment apertures for securing the flow line to the flange adapter.
US10450822B2 Hanger running system and method
A system includes a hanger locking assembly configured to lock a hanger within a housing of a wellhead. The hanger locking assembly includes an energizing ring having one or more axially-extending passageways configured to receive and to support one or more control lines. An anti-rotation element extends between the energizing ring and the hanger to block rotational movement of the energizing ring relative to the hanger. A locking ring is in contact with the energizing ring, and axial movement of the energizing ring relative to the hanger drives the locking ring radially to engaged position in which the locking ring extends into a corresponding recess of the housing of the wellhead to block axial movement of the hanger relative to the wellhead.
US10450818B2 Fluid release mechanism for a chemically-inflatable bag
The present invention is directed towards an apparatus for providing a nonlabor-intensive process for sealing an opening formed in the ground with a chemically-inflatable bag. The chemically-inflatable bag contains two or more chemical reactants, one of which is a liquid reactant that is initially stored in a liquid-containing device. The liquid-containing device has a removable cap, which upon removal or breakage of the cap permits the liquid reacting agent to contact and react with another reacting agent. The chemical reaction produces carbon dioxide, which expands the chemically-inflatable bag from a collapsed condition to an inflated condition. In the inflated condition, the chemically-inflatable bag fills and protects the integrity of the formed cavity.
US10450816B2 Bypass style hydraulic set and quarter turn tubing anchors
Embodiments of a tubing anchor catcher includes a setting and a stationary sleeve each containing a set of spaced-apart cone pieces at one end that form a cone block configured to engage a set of slips. The anchor catcher, which may be designed for hydraulic or rotational setting, provides a reduced outside diameter that allows room for gas or debris bypass as well as capillary or electrical lines to be banded along the outside of the tool while providing a full open inside diameter. Because there is area available between the slips, multiple lines may be banded to the tool. In some embodiments, one of the raised slip protectors may include a line carrier sized to receive a capillary or electrical line.
US10450814B2 Single ball activated hydraulic circulating tool
A circulating sub having an elongate outer member and an elongate inner member positioned within the outer member. Locking members releasably maintain the inner and outer members in a longitudinally fixed relationship. The sub may be activated by a single ball. The ball engages with the locking members and unlocks the inner member from the outer member. The increase of fluid pressure within the sub causes the inner member to move downward within the outer member. Downward movement of the inner member opens exit ports on the outer member to allow fluid to flow into a wellbore surrounding the sub. The decrease of fluid pressure within the sub causes the inner member to move upward within the outer member. Upward movement of the inner member seals the exit ports and deactivates the sub. Once the sub is deactivated, the ball may be expelled from the sub.
US10450802B2 Mobile offshore drilling unit, a method of using such a unit and a system comprising such a unit
An offshore well-processing system includes a mobile offshore drilling unit and a remote well-processing device configured to be positioned on an offshore platform different from the mobile offshore drilling unit, the mobile offshore drilling unit defining at least one well center and comprising at least one primary drill rig including at least one drill floor and at least one hoisting system for raising and lowering tubular equipment through the at least one well center from/into a well in the seafloor. The mobile offshore drilling unit and the remote well-processing device are configured to be operationally coupled to each other; and the mobile offshore drilling unit is configured to assist in performing concurrent well-processing tasks on respective wells, including the first well processing task performed by the remote well-processing device on a first well and a second well-processing task concurrently performed by the offshore well-processing system on a second well.
US10450800B2 Bearing/gearing section for a PDM rotor/stator
A moving or progressive cavity motor or pump is disclosed, the motor including a rotor and a stator, the stator having one or more inserts or gearing sections to limit a lateral movement of the rotor relative to the stator. In some embodiments, the motor or pump may include a rotor and a stator, the stator including: a first, helicoidal, section comprising a compliant material having a first compressibility; a second section, helicoidal, non-helicoidal, or combination thereof, having a second compressibility, wherein the second compressibility is less than the first compressibility.
US10450799B2 Attachable platform
An attachable platform providing a work surface affixed to the top cap of the ladder. The device includes a work surface and rails along the exterior edges of the work surface and slots therein. The slots receive an attachment device such as a hook and loop strap to attach the platform to the ladder. Protrusions are found on the back surface of the platform and are designed to accommodate the top cap of a ladder.
US10450797B2 Rolling shutter driving device and rolling shutter apparatus utilizing same
A rolling shutter driving device includes a motor, a locking assembly and a gearbox. The motor includes a stator and a rotor. The rotor includes a rotary shaft connected to the gearbox. The rotary shaft drives through the gearbox a rolling shutter to extend or retract. The locking assembly includes a brake pad slidingly fitted on the rotary shaft and a rotary member fixedly mounted to the rotary shaft. The brake pad is circumferentially fixed relative to the stator. The brake pad is slidable relative to the rotary shaft so as to be selectively engaged with the rotary member to lock the rotary shaft and hence hold the load in position, or disengaged from the rotary member to unlock the rotary shaft.
US10450795B2 Security gate
A gate unit includes a gate mount and a gate coupled to the gate mount for swinging movement between opened and closed positions. A latch assembly is coupled to the gate to lock the gate in the closed position. The gate unit can be mounted in a doorway.
US10450793B2 Security panel framing system and method
A security panel framing system having a base frame; a base plate under a base frame bottom side, the base plate having a stopper; a hollow inner channel defined by the base frame; a wedge having a wedge top side, and a wedge bottom side; a wedge wall extending between the wedge top side and the wedge bottom side; a reinforced end at the wedge bottom side; wherein the reinforced end and a bottom wedge lip are configured to be held in place by the stopper; a cap configured to be associated with the wedge; and wherein the wedge is configured to sit at a base plate front side leaving a gap between the wedge back side and the base frame, the gap being configured to receive a security panel, such that the security panel is snugly encased by the base frame and the wedge.
US10450789B2 Vehicle operation detecting device
A vehicle operation detecting device includes: a plurality of sensors that are arranged side by side in a vehicle and individually output a plurality of detection signals changing as a detection target touches or approaches the sensors; a peak position detector that detects a plurality of peak positions of the plurality of detection signals; an operation direction detector that detects a moving direction of the detection target in an arrangement direction of the plurality of sensors, based on an order of the plurality of peak positions; and a driving controller that controls a driving of an opening/closing member according to the detected moving direction.
US10450782B2 Apparatus and method for enhancing sound performance of a latch
A latch is provided. The latch having: a housing; an intermittent lever pivotally mounted to the housing for movement between a latched position and an unlatched position; and an elastomeric feature configured to contact the intermittent lever when it is in the latched position.
US10450779B2 Lock with linearly operating latch
A lock is provided, the lock having: a lock mechanism having a first member and a second member, the first member and the second member each being slidably mounted to a housing of the combination lock, wherein the first member is capable of movement between a first position and a second position and the second member is capable of movement between a first position and a second position and wherein movement of the first member from the first position to the second position causes the second member to move from the first position to the second position; a bolt configured for movement between a locking position and an unlocking position, the bolt preventing the second member from moving from the second position to the first position when the bolt is in the locking position.
US10450777B2 Digital lock
The invention provides a digital lock including at least two magnets. One magnet is a semi hard magnet and the other magnet is a hard magnet. The hard magnet is configured to open or close the digital lock. The semi hard magnet and the hard magnet are placed adjacent to each other. A change in magnetisation polarisation of the semi hard magnet is configured to push or pull the hard magnet to open or close the digital lock.
US10450772B2 Removable floor for a portable shelter
A removable floor for use with a portable shelter, the floor including a central section defining a ground engaging area and having at least one layer constructed of a non-permeable material, at least one side wall extending upward from and being connected to the central section at an edge of the ground engaging area and having an outward facing side wall fastener, and at least one initial locating fastener extending outward relative to the at least one side wall of the floor. The floor is usable in combination with a portable shelter having complementary fasteners for releasable connection of the floor to the shelter.
US10450771B2 Utility pole setting trailer
A utility pole setting trailer includes a horizontal frame configured to carry utility poles to remote locations, a set of wheels supporting the horizontal frame, a hydraulic boom coupled to the horizontal frame and configured to load and unload the utility poles on to the horizontal frame, and a motor coupled to the hydraulic boom and configured to power the hydraulic boom. The hydraulic boom includes a first arm and a second arm, and a grapple is coupled to a distal end of the second arm. The grapple is configured to grasp a respective utility pole. In addition, the horizontal frame includes a front portion and a rear portion that are configured to extend apart from each other to increase a length of the horizontal frame.
US10450770B2 Multi layered protection system
A multi layered protection system is provided that comprises a plurality of box-shaped structural elements, each having a frame made of beams, wherein the frame is bounded by a floor at a lower side, a roof at an upper side, and four sides, and wherein at least two box-shaped structural elements of the plurality are positioned adjacently to one another so as to form a modular protection structure having outer sides. The system further comprises a plurality of walls configured to bound the outer sides and at least one layer of protective wall configured to be mounted adjacent to said plurality of walls and the roof. A method of erecting the modular multi layered protection system in a site is also provided.
US10450766B2 Tanning ledge support structure
A swimming pool assembly, including a swimming pool body defining a pool top edge and an oppositely disposed bottom pool floor member connected by at least one pool wall and having a shallow deck portion and a support structure for providing support to the deck portion operationally connected to the deck portion and extending away from the pool top edge. The support structure further includes a support structure floor member, at least one support structure wall member extending therefrom and connected to the shallow deck portion to define an enclosure, and at least one fluid access aperture formed through the support structure wall member to provide fluidic communication with the enclosure.
US10450762B2 Tile end profile
An elongate profile (1) for terminating installed tiles includes, viewed in cross-section, a fastening leg (4) for fixing the profile to a base (10), wherein the fasting leg (4) defines a contact surface (2) and is provided with passage openings (3), and a boundary leg (5) adjoining the fastening leg (4) substantially vertically, wherein the outside (7) of the boundary leg (5) defines a visible surface. A stop leg (8) is further provided directly adjacent to the boundary leg (5) and extending downwardly in the direction of the fastening leg (4), the stop leg (8) including an angle (α) with the boundary leg (5) in the range between 5 and 30° and having a plurality of through holes (9).
US10450761B2 Ceramic tile and method for manufacturing ceramic tiles
Ceramic tile having a ceramic base layer and a cover glaze layer including a printed pattern, where the surface of the ceramic tile has a relief having structural features corresponding to the printed pattern. The structural features are at least partly formed in the surface of the ceramic base layer and manifest themselves through the glaze layer to the upper surface of the tile. Additionally, a method which allows for the manufacturing of such ceramic tiles.
US10450753B1 Enclosure with roof panels received in supporting channels
An illustrative example enclosure includes a support frame having longitudinal beams and lateral channel members that define an outward facing flow passage. A first roof panel and a second roof panel respectively include lateral edges aligned with the channel members. The lateral edge of the first roof panel is situated adjacent the lateral edge of the second roof panel. An interface between the lateral edge of the first roof panel and the lateral edge of the second roof panel is situated above or within the flow passage of one of the channel members. At least one seal engages the first roof panel and the second roof panel. The seal is received in the flow passage of the channel member in sealing engagement with the channel member.
US10450752B2 Fire resistant composite boards and methods
Embodiments of the invention provide roofing boards and roofing systems having improved fire resistance properties and methods related to the same. According to one aspect, a roofing system is provided. The roofing system includes roofing panels positioned atop structural support members to form a roof deck. Roofing boards are positioned atop the roof deck and coupled thereto and a roofing membrane is positioned atop the roofing boards and coupled therewith. The roofing boards include a coating of a mineral based material applied to one or more surfaces in an amount between the range of about 0.10 lbs/ft2 and about 0.70 lbs/ft2. The mineral based material coating enables the roofing boards to pass the UL 790 class A tests, such as the burning brand test.
US10450746B2 Folded dome like retractable opening structure and method
A Folded Dome like Retractable Opening Structure and Method of the present invention is an hourglass in external appearance with a narrow waist and a mirrored double truncated flexible cone-like structure, with one primary truncated flexible cone-like structure on bottom intermediately supported and connected by one secondary truncated flexible cone-like structure on top. The retractable opening of the present invention is the truncated open end of the primary truncated flexible cone-like structure, where it is flexible to expand to open toward and contract to close away from its peripheral. In operation, the double truncated flexible cone-like structure is a slider crank mechanism, where, power is applied to the secondary truncated flexible cone-like structure, the slider, which moves vertically; the primary truncated flexible cone-like structure, the crank, is rotated; and rotation of the primary truncated flexible cone-like structure forces its truncated open end, same as the retractable opening of the present invention, to uniformly move inward to close and outward to open. A Folded Dome like Retractable Opening Structure is especially suitable for expansive retractable roofs on domed structures often found on a sports stadium.
US10450743B2 Window and curtain wall mullions, transoms and systems
Window wall and curtain wall mullion or transom structures including a component made of a thermally insulating material covering substantially an entirety of an outer side of a metal structural segment where a first fastener passing through the metal structure and into the component is oriented generally parallel to the outer side or parallel to at least one outward facing surface of the metal segment. The insulating component includes a first slot and a second slot configure to receive fasteners where the slots are oriented generally perpendicularly. The component is devoid of penetrations passing through the component to the structure.
US10450742B2 Unbonded loosefill insulation
A loosefill insulation installation includes a loosefill insulation material made from fiberglass fibers. The loosefill insulation material unexpectedly has improved thermal performance, even through the amount of mineral oil applied to the fiberglass fibers is reduce. For example, the fiberglass fibers can be coated with a mineral oil in an amount that is between 0.1% and 0.6% of the weight of the fiberglass fibers, such as about 0.375%.
US10450741B2 Construction boards with coated inorganic facer
A construction board comprising (a) a foam core having a first planar surface and a second planar surface; (b) a facer, having first and second planar surfaces, including an inorganic fabric and a coating; and (c) an interfacial region between the foam core and said facer.
US10450739B1 Temporary or semi-permanent structure and method of increasing usable space
A structure with a support assembly having an upper surface spaced above a lower surface, a module removably supported by the upper surface of the support assembly, and an access system that is configured to allow a person adjacent the lower surface of the support assembly to move vertically upward adjacent the upper surface of the support assembly. The module at least partially encloses an interior space that is accessible through an opening in the module. The module is not permanently joined to the support assembly, and there is an accessible volume of space positioned below the module. The access system is positioned in a corner of a parking lot, the module extends laterally outward from the access system, and the module is positioned above at least one parking space in the parking lot.
US10450737B2 Structural modular building connector
A connector assembly, having an upper connector coupled to a lower connector and a gusset plate sandwiched between the upper and lower connectors. Also, disclosed is a hoistable connector assembly, a lifting frame assembly, a coupling system for modular frame units, a method for assembling a module unit using the connector assembly, and a modular frame unit and building having the connector assembly.
US10450733B2 Clean toilet and accessories
A toilet that includes a water tank having a vent hole; a bowl; and a system having a valve body connecting the tank and a fluid channel; a housing moveable relative to the valve body during a flush cycle to pass water from the tank into the bowl through the fluid channel, the housing having a bore that connects with the fluid channel; a fan in the bore that operates in first and second modes; a motor in the bore for rotating the fan in each mode; and a vent having an inlet fluidly connected with the bore and an outlet fluidly connected with the vent hole. In the first mode, the fan moves air from the bowl to the vent hole through the bore and vent; and in the second mode, the fan moves air from outside the tank to the bowl through the vent hole and bore.
US10450732B2 Fluid dispensing system, a system for processing waste material and a fluid monitoring system
Described herein is a fluid dispensing system, a system for processing waste material and a fluid monitoring system and a method of monitoring the quality of a fluid. One embodiment provides a fluid dispensing system (1) including a fluid dispenser (3) in fluid communication with at least one source of a first fluid. An identification device identifies a user of the system and generates a user identifier. A processor (19) is responsive to the user identifier to access a database (27) to retrieve user data indicative of one or more user preferences and, in response, generate a control signal. One or more electrical sensors (25) are configured to sense a gesture motion from the user and, in response, generate a local input signal. An actuator system (29) is responsive to the control signal and the local input signal to dispense the first fluid from the fluid dispenser with predefined characteristics.
US10450731B2 Faucet-integrated touch-free soap dispensing systems
Faucet-integrated touch-free soap dispensing systems are provided. A soap dispenser is at least partially integrated with a faucet, and includes a proximity sensor, a dispensing unit, and a soap dispensing outlet. The dispensing unit includes a soap reservoir and a pump mountable below a deck that supports the faucet, and is communicatively coupled to the proximity sensor and fluidly coupled to the soap dispensing outlet via a soap tube.
US10450728B2 Projection type display device and projection control method
Provided are a projection type display device and a projection control method capable of presenting suitable information to an operator both during traveling on a public road and during operation at a working site to perform assistance for the operator. A projection type display device that is mounted in a construction machine 100 having a windshield 5 performs a control so that image light is projected onto each of a first projection range 5A, a second projection range 5B, and a third projection range 5C of the windshield 5 in a case where it is determined that the location of the construction machine 100 is a working site, and performs a control so that image light is projected onto only the third projection range 5C of the windshield 5 in a case where it is determined that the location of the construction machine 100 is a public road.
US10450727B2 System and method for monitoring mining machine efficiency
A mining machine including a power monitor, a sensor, and a monitoring module. The power monitor is configured to measure a received power, and generate a total power consumption data based on the received power. The sensor senses payload of the mining machine to generate payload data. The monitoring module includes non-transitory computer readable media for comparing the total power consumption data and the payload data to generate mining machine efficiency data, determining an operator performance comparing the mining machine efficiency data and the operator performance, determining, based on the comparison of the mining machine efficiency data and the operator performance, at least one selected from the group consisting of a bank difficulty and a bank digability, and outputting the at least one selected from the group consisting of the bank difficulty and the bank digability.
US10450726B2 Pump control system of work machine
A work machine pump control system includes: a pump horsepower control valve (22) which causes a first urging force determining a limited horsepower (F) of a hydraulic pump and a second urging force due to a delivery pressure of the hydraulic pump to act on a spool in opposition to each other and which controls the pump flow rate such that it does not exceed the limited horsepower (F); a target pump flow rate computation section (42) computing a target pump flow rate based on an operation pressure (px) and a load pressure (py); a target horsepower computation section (41) which computes a required horsepower (Freq) corresponding to an operation pressure (px) from a relationship related to the operation pressure (px) and which computes a target horsepower (Ftar) based on the required horsepower (Freq); and a pump horsepower control section (35) which controls the pump horsepower control valve (22) such that the target pump flow rate (Qtar) is delivered with the limited horsepower (F) determined by the pump horsepower control valve (22).
US10450724B2 Work vehicle collective switch apparatus and work vehicle equipped with collective switch apparatus
A work vehicle collective switch apparatus includes: a switch operation unit including a plurality of switches; a network side signal output unit that outputs a switch state signal to an in-vehicle network side connected to the collective switch apparatus; a drive signal output unit that outputs a drive signal to a direct-coupled device connected to the collective switch apparatus, and a control unit that outputs a command signal corresponding to switch operation on a basis of switch assignment information that assigns in advance as to whether the drive signal is to be output from the drive signal output unit or the switch state signal is to be output from the network side signal output unit in accordance with switch operation of any of the plurality of switches.
US10450715B2 Powered lifting station for and method for lifting a slab foundation
A technician positions a form with a threaded aperture on a pier. Concrete is poured around the form to create a slab foundation. A fixture is then placed on the slab foundation, the fixture having a polygonal anti-rotation member that inserts into a polygonal upper end of the form. The fixture has an upward extending fixture stop member. A threaded rod with a tool adapter on its upper end is screwed into the threaded aperture. The adapter has an adapter stop member extending laterally relative to the fixture stop member. A power tool rotates the adapter to lift the slab foundation until the adapter stop member swings into contact with the fixture stop member. The technician then removes the adapter, places the adapter stop member adjacent an opposite side of the fixture stop member, then again rotates the adapter.
US10450714B2 Device for protecting against the scouring of granular fillings submerged in gravity structures
A device for protecting against the scouring of granular fillings submerged in gravity structures in which a filling with granular materials must be deposited once the structures are submerged, so that the structures reach a weight sufficient to en sure the stability thereof against the actions to which they are subjected. The device consists of one or more porous covers that sit and/or are secured as an upper closure of the structure to protect the inner filling, each of the covers having a plurality of openings that are distributed on the surface thereof and have a size suitable to allow the passage of the filling material, which filling material is transferred to the inside of the structure simply by pouring until a height close to the cover is reached, leaving a margin or chamber between the two that is suitable for generating an internal turbulence that dissipates wave energy and incident currents, thereby making it difficult for the filling material to escape from the inside through the openings.
US10450709B2 Self-propelled road milling machine for milling road surfaces, in particular large-scale milling machine, and method for milling road surfaces
In a self-propelled road milling machine for milling road surfaces comprising a milling roller housing arranged at the machine frame between the front and rear chassis axles, it is provided that the rear end, as seen in the direction of travel, of the milling roller housing is flush with a height adjustable stripper shield which laterally rests in the milling track of the milling roller and resiliently against a milling edge of the milling track extending orthogonally to the road surface.
US10450707B2 Gutter
The invention relates to a gutter element for draining, for example, road surfaces, which can be joined together to form a line of guttering. In order to seal off the connection, an elastic seal (30) is provided in the abutment region. In order to improve the hydraulic properties of the gutter, the cross-sectional profile of the invert (16) of the gutter (10) is substantially V-shaped. To improve sealing, the profile following the seal (30) in cross-section should be formed differently to that of the invert (16) in such a way that it has a constant maximum radius of curvature in the region of the gutter invert.
US10450700B2 Method and apparatus for controlling a cellulosic pulp process
A method and apparatus for controlling a cellulosic pulp process for producing a pulp product having a desired pulp property is disclosed. The method involves illuminating an in-process portion of pulp using a first wavelength of light, and receiving a scattered light spectrum from the illuminated portion of pulp, the scattered light spectrum including spectral components that have been shifted in wavelength through interaction with a constituent of the illuminated portion of pulp. The method also involves filtering the scattered light spectrum to separate the spectral components, and identifying spectral features in the filtered scattered light spectrum that correspond to the pulp property. The method further involves generating a control signal for controlling the pulp process based on variations in the identified spectral features to cause the pulp property to fall within a desired range.
US10450697B2 Space frame radome comprising a polymeric sheet
The invention relates to a space frame radome comprising a sheet, said sheet comprising high strength polymeric fibers and a plastomer, wherein said plastomer is a copolymer of ethylene or propylene and one or more C2 to C12 alpha-olefin co-monomers and wherein said plastomer has a density as measured according to ISO1183 of between 860 and 940 kg/m3 and wherein the sheet has an areal density that is with at most 500% higher than the areal density of the high strength polymeric fibers.
US10450696B2 Floating linear tension member comprising multiple fibers
Linear tension member having multiple fibers and at least 0.1 wt % of solid hydrophobic organic nanoparticles with a mean diameter of 10-300 nm and a standard deviation σ of at least 10% of the mean value, which linear tension member has a linear mass density of at least 10.000 dtex and has at least 80 wt % of fibers having a mass density higher than 1 g/cm3. The disclosure also pertains to the use of such particles for making a linear tension member buoyant and to a process to manufacture a floating linear tension member.
US10450695B2 Compositions and methods of biologically cemented structures for marine applications
The invention is directed to kits, compositions, tools and methods for biologically cemented structures. More particularly, the invention is directed to materials and methods for the farming of bivalves, such as oysters and clams, and also other marine and fresh water invertebrates such as sponges, and other commercially worthwhile sessile organisms. The kits, compositions, tools and methods of the invention are also applied to erosion control of beaches and underwater surfaces, for the formation of foundations such as footings for pier supports, marine walls and other desirable structures.
US10450694B2 System and method of generating a pattern or image on fabric with linear laser irradiation, fabric made by said method, and products made with said fabric
A method of scribing abrasion aesthetics, patterns, images, serial numbers, ply markings and/or other information, such as sizing or care information, on fabric such as denim, before or during the fabric cutting process is provided. The method comprises loading the panel abrasion software, pattern marker software, and fabric scribing software; placing the fabric on a flat surface under at least one laser; laser scribing ply numbers, serial labels, fabric markers, and panel abrasions on the fabric; cutting the fabric into fabric lengths; spreading the pre-abraded and pre-marked fabric lengths on top of each other to create multiple plies in precise alignment; cutting shaped panels along the lines of the pattern marker with a conventional knife, laser, or other appropriate cutting tool; and stacking the abraded, labeled and shaped panels robotically or manually for sewing.
US10450687B2 Washing machine having a manual washing unit
Disclosed is a washing machine capable of improving the efficiency of washing and product quality by improving a pivoting structure of a door assembly having a door and an auxiliary washing unit forming an auxiliary washing space. Also, the door and the auxiliary washing unit may be coupled by a locking part so that a user can open and close the door assembly conveniently when manual washing is not needed. When manual washing is needed, the user may release a locked state of the locking part to move the door and the auxiliary washing unit separately.
US10450685B2 Methods for distressing fabrics or garments using polysaccharide particles
The present disclosure relates to methods for distressing an object by projecting polysaccharide particles onto a surface of the object. The present disclosure relates also to methods for cleaning the distressed fabric or garment and optionally methods for recycling the polysaccharide particles. In one embodiment, a method for distressing an object comprises suspending polysaccharide particles in a gas, creating a suspension, and projecting the suspension onto an object.
US10450684B2 Sewing quality control in sewing machine
Disclosed is a sewing machine which evaluates sewing quality using a stitch tightness index. During sewing operation, a used length of an upper thread per stitch is detected, and a stitch tightness index per sewn stitch is calculated on the basis of a stitch length per stitch defined by sewing pattern data, a fabric thickness of a sewing workpiece, and detected data of the used length of the upper thread. Then, notification is made which corresponds to the calculated stitch tightness index per sewn stitch (such as a visual display of the stitch tightness index). After that, acceptability/non-acceptability of the thread tightness per sewn stitch can be determined by comparing the calculated stitch tightness index per sewn stitch against a reference value, and a result of the determination can be notified.
US10450680B2 Multi-purpose tool for making crafts
An improved multi-purpose tool useful for creating various crafts using yarn is disclosed. The tool comprises a bottom portion and a top portion. The bottom portion comprises one or more bottom members, the one or more bottom members having a space in between and extending downwards and generally parallel to each other at ends of the one or more bottom members. The upper portion comprises one or more upper members, the one or more upper members having a space in between and extending upwards and generally parallel to each other at ends of the one or more upper members. The tool also includes one or more notches contained in the ends of the one or more bottom members and in the ends of the one or more upper members. The notches along with the upper and/or bottom portions allow a user to create a variety of crafts using the same tool. The tool may also include one or more holes to help the yarn used for crafting from getting twisted. The bottom and upper portions together form different shapes for the tool such as Y-shape, H-shape, X-shape etc. Additionally, the tool may function as a sling shot.
US10450679B2 Flame-retardant fabric, method for producing same and fireprotective clothes comprising same
A flame-retardant fabric may include a cellulosic fiber and a modacrylic fiber, the cellulosic fiber being a natural cellulose fiber containing a phosphorus compound, the modacrylic fiber containing an antimony compound, the flame-retardant fabric including the modacrylic fiber containing the antimony compound in an amount of 14 to 54 wt %, antimony in an amount of not less than 1.7 wt %, and phosphorus in an amount of 0.3 to 1.5 wt % with respect to the total weight of the flame-retardant fabric, and the flame-retardant fabric having a weight per unit area of not less than 160 g/m2. The flame-retardant fabric can be produced by subjecting a fabric including a natural cellulose fiber and a modacrylic fiber containing an antimony compound to flame-retardant treatment with a phosphorus compound.
US10450673B2 Method of synthesis and purification of a nucleoside and/or a nucleotide, a modified nucleoside and/or nucleotide, a DNA molecule and an oligonucleotide library comprising said modified nucleoside and/or nucleotide and the use of said oligonucleotide library
The object of the invention is a method of synthesis and purification of a nucleoside and/or a nucleotide being a mono-, di- or triphosphate, wherein a Huisgen' s azide-alkyne cycloaddition reaction is being performed using a compound of structure (1) with a compound chosen from the group of structures (2) to (5). The object of the invention is also a modified nucleoside and/or nucleotide of structure (10), a DNA molecule and an oligonucleotide library comprising one or more modified nucleotides and the use of said oligonucleotide library for aptamers selection.
US10450671B2 SiC single crystal and method for producing same
Provided is a SiC single crystal that has a large growth thickness and contains no inclusions. A SiC single crystal grown by a solution process, wherein the total length M of the outer peripheral section formed by the {1-100} faces on the {0001} growth surface of the SiC single crystal, and the length P of the outer periphery of the growth surface of the SiC single crystal, satisfy the relationship M/P≤0.70, and the length in the growth direction of the SiC single crystal is 2 mm or greater.
US10450670B2 Methods for growing a crystal ingot with reduced dislocations from a crucible
Methods for growing a reduced dislocation crystal ingot in an ingot growing system are disclosed. The system has a first crucible with a first base and a first sidewall extending upward from the first base to define an outer cavity. The method includes placing a weir in the outer cavity, placing a second crucible on the weir, placing feedstock material into the outer cavity, and melting the feedstock material to allow movement of the melt from the outer cavity inward of an intermediate cavity and into an inner cavity.
US10450666B2 Copper plating solution and copper plating method
A copper plating solution includes: water-soluble copper salt; ethylenediamine; at least one of EDTA, a substituted derivative of EDTA, an ethylenediamine derivative, or glycine; and at least one of hydantoin or a substituted derivative thereof. The copper plating solution allows an aluminum or aluminum alloy base to be displacement-plated with copper.
US10450654B2 Radical gas generation system
In a radical gas generation system according to the present invention, a process chamber apparatus includes a table that causes a target object to rotate. A radical gas generator includes a plurality of discharge cells. Each of the plurality of discharge cells includes an opening. The opening is connected to the inside of the process chamber apparatus and faces the target object. Through the opening, a radical gas is output. Of the plurality of discharge cells, a discharge cell located farther from a center position of the rotation of the target object in a plan view includes a larger facing surface area that is a region in which a first electrode member and a second electrode member face each other.
US10450652B2 Synthesis of structured carbon material from organic materials
A method of forming a carbonized composition includes providing an organic composition, forming a protective layer over the organic composition, increasing temperature to carbonize the organic composition and for a period of time to form the carbonized composition, and removing the protective layer from the carbonized composition.
US10450651B2 Article comprising metal oxide-containing coating
Provided is an article having a novel surface with a texture different from conventional kinds. The article having a metal oxide-containing coating provided by the present invention comprises a substrate and a metal oxide-containing coating provided to the substrate surface. The metal oxide-containing coating has a Vickers hardness of 350 or higher, a surface roughness Ra of 300 nm or less, and a 20° gloss value of 50 or higher.
US10450647B2 Hard and low friction nitride coatings
A hard, wear resistant coating and a method of forming the coating on a substrate to be exposed to hydrocarbons is provided. A substrate is provided in a chamber. A film is deposited onto the substrate by physical vapor deposition (PVD), where the film includes a bulk layer and an outer termination layer. The deposition of the termination layer is mitigated. The termination layer is removed from the film, leaving the remaining bulk layer disposed over the substrate. And when the substrate is exposed to hydrocarbons in an environment having wear additives, friction modifiers, or naturally occurring compounds, a durable tribological layer is formed on an outer surface of the bulk layer to create a coating having low friction and anti-wear properties.
US10450646B2 Vapor deposition mask and organic EL display device
The purpose is providing a vapor deposition mask with high rigidity which can evaporate a uniform thickness film. A vapor deposition mask including a mask body having a main opening, a side surface of the main opening, an upper surface intersecting the side surface, and a lower surface opposing the upper surface, a first insulator contacting the lower surface, and a second insulator contacting the upper and side surfaces, wherein the first insulator includes a first region inside the main opening, and a first opening in the first region, the second insulator includes a second region inside the main opening, and a second opening in the second region, the mask body is sandwiched between the first and second insulators, and one of the first and second insulators includes a region located inside the main opening more centrally than the other and not overlapping with the other and the mask body.
US10450645B2 Coating system and process
A coating system for coating a part (10), such as a turbine blade or vane, has a mask (14) positioned adjacent to a first portion (16) of the part (10) to be coated and a mechanism (30) for moving the mask (14) relative to the part (10). The mechanism (30) may be a gear mechanism or a magnetic mechanism.
US10450641B2 Densified superconductor materials and methods
Methods of pre-densifying a metal wire containing superconductor materials are provided. Superconductor materials containing the pre-densified wires also are provided. The wires may be pre-densified by subjecting a metal wire that includes one or more filament cavities in which a superconductor precursor powder is disposed to a temperature and a first pressure for a time sufficient to densify the superconductor precursor powder to form a pre-densified metal wire, wherein the temperature is less than the melting point of the superconductor precursor powder, and the first pressure is sufficient, at the temperature, to compress at least a portion of the metal wire.
US10450639B2 Heat treatment to improve joinability of aluminum sheet
In at least one embodiment, an assembly is provided comprising a first member including a 6xxx series aluminum alloy heat treated to have a yield strength of at least 200 MPa and an r/t (bendability) ratio of up to 0.4. One or more members may be secured to the first member with a rivet (e.g., a self-piercing rivet). The heat treated alloy may have a yield strength of at least 260 MPa and may have a bendability ratio of up to 0.3. A method of forming an assembly is also provided, including heat treating a 6xxx series aluminum alloy to produce an alloy having a yield strength of at least 200 MPa and an r/t (bendability) ratio of up to 0.4 and riveting a member including the heat treated alloy to one or more additional members.
US10450636B2 Aluminum alloys and manufacture methods
A composition comprises, in weight percent: Al as a largest constituent; 3.0 6.0 Cr; 1.5 4.0 Mn; 0.1 3.5 Co; and 0.3 2.0 Zr.
US10450635B2 High strength and high corrosion-resistance nickle-based alloy with superior hot forgeability
Provided is a high strength and high corrosion-resistance Ni-based alloy having excellent hot forgeability, which is suitable for a member for oil drilling, the Ni-based alloy having a composition consisting of, by mass %, 42.1 to 45.5% of Cr, 0.5 to 2.5% of Nb, 1.2 to 2.0% of Ti, 0.0001 to 0.0090% of Mg, 0.001 to 0.040% of N, 0.01 to 0.50% of Mn, 0.001 to 0.050% of Si, 0.01 to 1.00% of Fe, 0.01 to 2.50% of Co, 0.001 to less than 0.500% of Cu, 0.001 to 0.050% of Al, 0.005 to less than 0.100% of V, 0.0001 to 0.0100% of B, 0.001 to 0.050% of Zr, and the balance of Ni with inevitable impurities, and the composition preferably further consists of any one of 0.1 to 1.5% of Mo, 0.1 to 1.5% of W, 0.001 to less than 0.050% of Ca, and 0.001 to less than 0.050% of Ta.
US10450632B2 Chelating polymeric membranes
The present application offers a solution to the current problems associated with recovery and recycling of precious metals from scrap material, discard articles, and other items comprising one or more precious metals. The solution is premised on a microporous chelating polymeric membrane. Embodiments include, but are not limited to, microporous chelating polymeric membranes, device comprising the membranes, and methods of using and making the same.
US10450629B2 Use of novel compounds for selectively extracting rare earths from aqueous solutions including phosphoric acid and associated extraction method
The invention relates to the use, as an extraction agent for extracting at least one rare earth from an aqueous phase including phosphoric acid, of at least one compound of the following general formula (I): where n is an integer equal to 0, 1 or 2, R1 and R2 are H or an aliphatic hydrocarbon group, one of R3 and R4 has the following formula (II): where R5 and R6 are a hydrocarbon, hydroxyl or alkoxyl group, and the other one of R3 and R4 has one of the following formulas (II′) and (III): where R5′ and R6′ are a hydrocarbon, hydroxyl or alkoxyl group, and R7 and R8 are H or an aliphatic hydrocarbon group. The invention also relates to a method for recovering at least one rare earth using said compound, as well as to specific compounds as such.
US10450628B2 High-strength austenitic stainless steel having excellent hydrogen embrittlement resistance characteristics and method for producing same
This high-strength austenitic stainless steel having excellent hydrogen embrittlement resistance characteristics includes, by mass %, C: 0.2% or less, Si: 0.3% to 1.5%, Mn: 7.0% to 11.0%, P: 0.06% or less, S: 0.008% or less, Ni: 5.0% to 10.0%, Cr: 14.0% to 20.0%, Cu: 1.0% to 5.0%, N: 0.01% to 0.4%, and 0: 0.015% or less, with the balance being Fe and unavoidable impurities, wherein an average size of Cr-based carbonitrides is 100 nm or less, and an amount of the Cr-based carbonitrides is 0.001% to 0.5% in terms of % by mass.
US10450622B2 Method for heat-treating a manganese steel product and manganese steel product
A method for heat treating a manganese steel product whose alloy comprises: a carbon fraction (C) between 0.09 and 0.15 wt. %, and a manganese fraction (Mn) in the range of 3.5 wt. %≤Mn≤4.9 wt. %, the method comprising: performing a first annealing process (S4.1) with the substeps heating (E1) the steel product to a first holding temperature (T1), which lies above 780° C., holding (H1) the steel product during a first time period (Δ1) at the first holding temperature (T1), cooling (A1) the steel product, performing a second annealing process (S4.2) with the substeps heating (E2) the steel product to a holding temperature (T2), which lies above 630° C. and below 660° C., holding (H2) the steel product during a second time period (Δ2) at the holding temperature (T2), cooling (A2) the steel product.
US10450621B2 Low alloy high performance steel
A low alloy, high performance steel having high impact toughness and high ductility, as well as methods of making and heat treating the alloy, are provided. The alloy steel composition consists essentially of about 0.24% to about 0.32% carbon, about 2.00% to about 3.00% chromium, about 0.50% to about 1.50% molybdenum, about 0.05% to about 0.35% vanadium, about 1.00% manganese or less, about 3.00% nickel or less, about 1.50% silicon or less, with minimal impurities, and balance consisting essentially of iron, wherein % is weight percent based on the entire weight of the alloy steel composition. The impurities may include about 0.20% copper or less, about 0.015% phosphorous or less, about 0.012% sulfur or less, about 0.02% calcium or less, about 0.15% nitrogen or less, and/or about 0.025% aluminum or less. Also disclosed is a hardened and tempered article that has high impact toughness, as well as other favorable physical properties.
US10450616B1 Polynucleotides for the amplification and detection of Chlamydia trachomatis
The invention provides methods and compositions for the detection of Chlamydia trachomatis in a test sample. Its presence or absence in the sample is determined by nucleic acid based testing methods using primers and/or probes and or molecular beacons that bind to the 23S ribosomal genes or gene transcripts.
US10450614B2 Mutation detection assay
A method of sample analysis is provided. In certain embodiments, the method involves: a) amplifying a product from a sample that comprises both wild type copies of a genomic locus and mutant copies of the genomic locus that have a point mutation relative to said wild type copies of the genomic locus, to produce an amplified sample, where: i. the amplifying is done using a first primer and a second primer; and ii. the first primer comprises a 3′ terminal nucleotide that base pairs with the point mutation and also comprises a nucleotide sequence that is fully complementary to a sequence in the locus with the exception of a single base mismatch within 6 bases of the 3′ terminal nucleotide; and b) detecting the presence of said product in said amplified sample using a flap assay that employs an invasive oligonucleotide. A kit for performing the method is also provided.
US10450613B2 EGFR/NEDD9/TGF-β interactome and methods of use thereof for the identification of agents having efficacy in the treatment of hyperproliferative disorders
Compositions and methods for the treatment and diagnosis of cancer are disclosed.
US10450606B2 Compositions and methods for accurately identifying mutations
The present disclosure provides compositions and methods for accurately detecting mutations by uniquely tagging double stranded nucleic acid molecules with dual cyphers such that sequence data obtained from a sense strand can be linked to sequence data obtained from an anti-sense strand when sequenced, for example, by massively parallel sequencing methods.
US10450601B2 Buffer composition for hybridization use, and hybridization method
A buffer composition for hybridization of a target nucleic acid is provided. The nucleic acid can include a nucleotide to be detected with a nucleic acid probe. The probe can contain a nucleotide sequence complementary to the target nucleic acid. The buffer can include a blocking nucleic acid having a nucleotide sequence complementary to a non-target nucleic acid having a nucleotide not to be detected corresponding to the nucleotide to be detected. The buffer composition can suppress non-specific hybridization to the nucleic acid probe even when a non-target nucleic acid is present. The use of the buffer composition can achieve excellent detection efficiency of the target nucleic acid.
US10450599B2 Fractional initiator hybridization chain reaction
The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR is dependent upon two or more of these split initiators being brought into proximity (e.g., via binding events mediated by a target) such that a full initiator is formed that is capable of triggering HCR signal amplification.
US10450596B2 L-2-hydroxyglutarate and stress induced metabolism
The present disclosure provides, among other things, methods and compositions for diagnosing and treating stress-induced injuries, hypoxia in particular. The present invention is based, in part, on the novel discovery that a metabolite, L-2-hydroxyglutarate, and certain enzymes and substrates regulating its metabolism, mediate stress-induced cellular mechanisms. In some embodiments, provided methods and compositions are used to diagnose and treat diseases with hypoxia-induced injuries. In some embodiments, provided methods and compositions are used to modulate cell pluripotency or differentiation in vivo or in vitro.
US10450585B2 Delivery methods and compositions for nuclease-mediated genome engineering
The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a cell.
US10450581B2 Cloning and exploitation of a functional R-gene from Solanum chacoense
The invention relates to a resistance gene and functional homologs or fragments thereof isolated from S. chacoense, S. berthaultii, S. sucrense or S. tarijense. Moreover, the invention relates to the use of said resistance gene, for example the use of said resistance gene in a method to increase or confer at least partial resistance in a plant to an oomycete infection.The invention provides an isolated or recombinant nucleic acid sequence comprising a nucleic acid sequence encoding one of the amino acid sequences of FIG. 4 or a functional fragment or a functional homolog thereof such as those presented in FIG. 13.
US10450577B2 Root-preferred promoter from a Panicum virgatum metallothionein-like gene
This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a Panicum virgatum metallothionein-like gene (mtl). Some embodiments relate to a promoter from a Panicum virgatum metallothionein-like gene (mtl) that functions in plants to promote transcription of operably linked nucleotide sequences.
US10450573B2 Compositions and methods for regulation of gene expression with, and detection of, folinic acid and folates
Aptamers that specifically bind to ligands of folinic acid, a folate, and derivatives thereof (which may be referred to herein as ligands) are provided, and compositions and methods of use thereof. The aptamers and switches of the invention provide biological sensing capability for detecting the ligands, and are effective in sensing in vitro and in vivo. By specific sensing of the ligand, the aptamers of the invention provide a means of engineering an inducible gene regulatory system that enables dose-dependent control over gene expression in response to the ligand, in vivo and in vitro.
US10450571B2 Small interfering RNA (siRNA) for the therapy of type 2 (ADO2) autosomal dominant osteopetrosis caused by CLCN7 (ADO2 CLCN7-dependent) gene mutation
The present invention lies in the field of molecules known as “small interfering RNA” with therapeutic applications. siRNAs have the ability to reduce gene expression in an extremely specific way (1). These are small sequences of double-strand RNA, normally used in laboratory to modify cell function, which revolutionized cell biology by allowing previously precluded molecular manipulations.
US10450570B2 Compositions and methods for controlling vasculature
The invention relates to compositions and methods for reducing excessive vascular development and treat related disorders. In one aspect, the invention provides methods for treating, reducing or inhibiting vascular development in a subject in need thereof. The methods of the invention comprises administering to the subject an effective amount of a HK2 depleting agent that decreases the level of expression and/or activity of HK2. In some embodiments, the level of expression and/or activity of fibroblast growth factor receptor (FGFR), FGF ligand and/or FGF signaling is/are decreased. The invention also includes methods for diagnosing excessive vascular development and for measuring the efficacy of a treatment for an excessive vascular development in a subject in need thereof. The invention further includes a pharmaceutical composition for treating or reducing angiogenesis or lymphangiogenesis, comprising a HK2 depleting agent and a pharmaceutical acceptable carrier.
US10450569B2 Methods and compositions of short small hairpin RNAS and microRNAS for wound healing
Wound healing is a complex homeostatic process in which several distinct types coordinate to repair a physical damage. Failure to close wounds contributes to the pathology of conditions like diabetes mellitus, particularly in the elderly. Presented herein are molecules, pharmaceutical compositions, and methods for applying small RNA oligonucleotide technology to wound healing. Small RNA oligonucleotide approaches as disclosed herein provide a therapeutic strategy for improving both basal and pathological wound healing.
US10450568B2 Oligonucleotide compositions and methods thereof
Among other things, the present disclosure relates to designed oligonucleotides, compositions, and methods thereof. In some embodiments, provided oligonucleotide compositions provide altered splicing of a transcript. In some embodiments, provided oligonucleotide compositions have low toxicity. In some embodiments, provided oligonucleotide compositions provide improved protein binding profiles. In some embodiments, provided oligonucleotide compositions have improved delivery. In some embodiments, provided oligonucleotide compositions have improved uptake. In some embodiments, the present disclosure provides methods for treatment of diseases using provided oligonucleotide compositions.
US10450566B2 Compounds for inducing anti-tumor immunity and methods thereof
Described herein is a previously unknown function of XBP1 in controlling anti-tumor immunity. It is shown that inhibiting XBP1 in tumor-associated dendritic cells inhibits tumor growth and induces protective anti-tumor immune responses.
US10450564B2 Micromirs
The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions.
US10450561B2 Method for increasing implantation success in assisted fertilization
The present invention relates to a method for determining an uterine receptivity profile in order to increase implantation success in assisted fertilization.
US10450555B2 Preparation of multi-hapten mutant G6PDH conjugates and their use for detection of multiple analytes
The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.
US10450554B2 Proline specific endoprotease
The present invention relates to a polypeptide having proline-specific endoprotease activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 70%, 75%, 80%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 70%, 75% 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1. The invention further relates to a method of producing the polypeptide and a process for the preparation of a food or feed product wherein the polypeptide is used.
US10450553B2 Polypeptides having protease activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having protease activity, and polynucleotides encoding the polypeptides. The invention further relates to the use of such polypeptides in detergent and/or in cleaning processes. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides.
US10450547B1 Medium system and method for ex vivo expansion of NK cells
This invention relates to a medium system and a method for ex vivo expansion of natural killer (NK) cells. This invention directly cultures Ficoll-separated PBMC by using immobilized anti-CD137 and RetroNectin, and uses OK-432 as a biological effector under the co-existence of GM-CSF, IL-4, IL-2, IL-15, and IL-21 for ex vivo activation and proliferation of NK cells, creating an efficient method for ex vivo expansion of NK cells. The expression rate of NK cells CD3-CD16+/CD56+ prepared by the method is as high as 92.5% or more. After 14 days of culture, NK cells can be expanded 1000 to 2000 times and have strong in vitro cytotoxic activity.
US10450543B2 Pipette tip for electroporation device
Provided herein is a pipette tip for electroporation including an outer surface, a void located within the outer surface, and a conductor located at least partially on or within the outer surface, in electrical communication with at least a portion of the outer surface and the void. Further provided herein is a pipette tip for electroporation including a body, a connector, and an elongated part. The connector is located at the distal end of the body and further includes at least one connecting post, a connecting part in mechanical communication with the connector, and a conductor located at least partially on or within the connector, wherein the conductor surrounds at least a portion of the connecting post. The elongated part also has a void and is located at the distal end of the connector. The void of the body, connector, and elongated part are in fluid communication.
US10450542B2 Apparatuses for and methods of processing cells and related structures
Apparatus for processing life-based organic particles, including particles selected from the list comprising cells, cellular spheroids, tissues, eukaryotes, micro-organisms, organs or embryos, comprises a hollow volume (10) that (a) is internally divided into at least first (14), second (16) and third (17) sub-volumes by at least two phaseguides (12, 13) formed inside the volume and (b) includes parts that are relatively upstream and relatively downstream when judged with reference to the movement of a meniscus or a bulk liquid in the volume (10). The apparatus includes at least first, second and third fluid conduits (19, 21, 22) connected to permit fluid communication between the upstream exterior of the volume (10) and a respective said sub-volume (14, 16, 17); and at least one further conduit (24) connected to permit fluid communication between the downstream exterior of the volume (10) and a said sub-volume. The first sub-volume (14) contains one or more life-based particles supported in or by a gel or gel-like substance; and the second sub-volume (16) communicates with the first sub-volume so as to permit transport of substances between the first and second sub-volumes (14, 16) and contains at least one gel or gel-like substance.
US10450538B2 Detergent unit doses and methods of producing the same
A unit dose of detergent and methods for producing the same are provided. In accordance with one embodiment, a unit dose comprises a body having a viscosity of from about 200,000 centipoise to about 50,000,000 centipoise at a working temperature of from about 0 to about 50 degrees Celsius, where the body has a bloom value of about 200 grams or more at the working temperature. The body comprises a detergent surfactant at from about 1 to about 40 weight percent based on the total weight of the body, and the body comprises a thickener at from about 10 to about 40 weight percent based on the total weight of the body.
US10450533B2 Methods and devices for producing biodiesel and products obtained therefrom
Methods and devices for economically producing a purified biodiesel product from feedstocks. Some embodiments of the methods comprise using at least one of a crude feedstock pretreatment process and a free fatty acid refining process prior to transesterification and the formation of crude biodiesel and glycerin. The crude biodiesel is then subjected to at least one biodiesel refining process which, in conjunction with feedstock pretreatment and free fatty acid refining produces a purified biodiesel product that meets multiple commercial specifications. A wide variety of feedstocks may be used to make biodiesel that otherwise would not meet the same commercial specifications, including corn oil, used cooking oil, poultry fats, fatty acid distillates, pennycress oil, and algal oils. The combination of feedstock refining and biodiesel refining processes is necessary to reduce problems associated with feedstocks having waxes, high free fatty acid levels, unacceptable color, high unsaponifiables levels, and high sulfur levels.
US10450532B2 Organic compounds and their use as fragrance ingredients
A compound represented by the formula I wherein is indicating a double bond either at C4 or at C5, or single bonds, R1, R2, R3, R4 are independently selected from H or Me, and R5, R6 are independently selected from Me or Et, and wherein the compound is not 9-hydroxy-5,9-dimethyldec-4-enal or 9-hydroxy-5,9-dimethyldecanal. Said compounds are useful as perfume ingredients in personal care and household care products.
US10450528B2 Lubricant composition
A lubricant composition improves a performance of reducing a formation of compressor deposit. The lubricant composition also ensures low temperature properties of the lubricant composition. The lubricant composition includes 14 mass % or more of a fraction having a boiling point of 500° C. to 550° C. and 5 mass % or more of a fraction having a boiling point of over 550° C.
US10450524B2 Synergistic detergent and active metal compound combination
The present invention relates to compositions containing a detergent composition and an active metal containing compound, where the detergent composition includes a quaternary ammonium salt detergent and optionally an oxygen-containing detergent, and where the active metal containing compound is in the form of a colloidal dispersion, comprising an organic phase, particles of an iron compound in its amorphous form, and at least one amphiphilic agent. These compositions may be used in fuels and provide improved engine performance when such fuels are used, specifically by reducing fuel injector fouling in the engine and/or by improving the regeneration of the engine's particulate exhaust trap.
US10450522B2 Integrated PTSA/membrane method and system for H2S and CO2 removal from biogas
Biogas containing H2S and CO2 is upgraded by removing H2S using PTSA and CO2 using two stages of gas separation membranes. The first stage permeate may optionally be used a regeneration gas stream. The second stage permeate may optionally be used a cool down gas stream. The PTSA unit includes two or more adsorbent beds each selective for water, VOCs, and H2S over CO2 and for H2S over methane.
US10450521B2 Renewable hydrocarbon composition
The present application provides a composition comprising 8-30 mass % of C4-12 linear alkanes, 5-50 mass % of C4-12 branched alkanes, 25-60 mass % of C5-12 cycloalkanes, 1-25 mass of C6-12 aromatic hydrocarbons, no more than 1 mass% of alkenes, and no more than 0.5 mass % in total of oxygen-containing compounds; wherein the total amount of C4-12 alkanes is 40-80 mass %, and the total amount of C4-12 alkanes, C5-12 cycloalkanes and C6-12 aromatic hydrocarbons is at least 95 mass %; and wherein the amounts are based on the mass of the composition. Also described is a method for producing the composition comprising the step of hydroprocessing a biological feedstock using a catalyst and the step of fractionating the product of the hydroprocessing step.
US10450517B2 Production of upgraded extract and raffinate
Systems and methods are provided for producing upgraded raffinate and extract products from lubricant boiling range feeds and/or other feeds having a boiling range of 400° F. (204° C.) to 1500° F. (816° C.) or more. The upgraded raffinate and/or extract products can have a reduced or minimized concentration of sulfur, nitrogen, metals, or a combination thereof. The reduced or minimized concentration of sulfur, nitrogen, and/or metals can be achieved by hydrotreating a suitable feed under hydrotreatment conditions corresponding to relatively low levels of feed conversion. Optionally, the feed can also dewaxed, such as by catalytic dewaxing or by solvent dewaxing. Because excessive aromatic saturation is not desired, the pressure for hydrotreatment (and optional dewaxing) can be 500 psig (˜3.4 MPa) to 1200 psig (˜8.2 MPa).
US10450513B2 High viscosity base stock compositions
Methods are provided for producing Group II base stocks having high viscosity and also having one or more properties indicative of a high quality base stock. The resulting Group II base stocks can have a viscosity at 100° C. and/or a viscosity at 40° C. that is greater than the corresponding viscosity for a conventional Group II base stock. Additionally, the resulting Group II base stocks can have one or more properties that are indicative of a high quality base stock.
US10450511B2 Production of hydrocarbon product and selective rejection of low quality hydrocarbons from bitumen material
Methods are described for the production of a hydrocarbon product and selective rejection of low quality hydrocarbons from a bitumen-containing material, where product quality, production yield, processing input requirements, and environmental benefits are assessed for selecting a candidate method for deployment. The methods facilitate selection and deployment of sustainable hydrocarbon production operations rather than focusing on maximizing volumetric yield of hydrocarbons.
US10450508B2 Bimesogenic compounds and mesogenic media
The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula l in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.
US10450500B2 Thermally stable polymers for enhanced oil recovery
Disclosed herein are polymer compositions useful in high temperature enhanced oil recovery applications. The polymer compositions include at least 20 mol % of an N,N-dialkyl-N,N-diallylammonium salt and further have a net negative charge. The polymer compositions provide polymer dispersions in water or brine having stable viscosity when maintained at temperatures of 100° C. and above for at least 2 days.
US10450495B2 Settable, form-filling loss circulation control compositions comprising in situ foamed calcium aluminate cement systems and methods of using them
This document relates to settable, hydraulic, non-Portland foamed cement compositions comprising nitrogen gas-generating compositions used for loss circulation control.
US10450494B2 Cement slurries for well bores
Cement slurries are provided for use in cementing oil and gas wells. The cement slurry comprises API Class C or Class H Portland cement and a pozzolan selected from the group consisting of pumice and mixtures of pumice and fly ash. Pumice is present in the mixtures in amounts at least about 40 wt % of the pozzolan. The weight ratio of the pozzolan to the cement is from about 35:65 to about 70:30. The novel cement slurries preferably will not comprise any additional lime, including hydrated lime, or other activators.
US10450488B2 Heat transfer compositions having improved miscibility with lubricating oil
A composition including 2,3,3,3-tetrafluoropropene and a lubricating oil including a polyalkylene glycol and a polyol ester, the polyol ester content in the lubricating oil being less than or equal to 25%. A method of lubricating a vapor compression circuit, the method including using a mixture including a polyalkylene glycol and a polyol ester as lubricating oil in the vapor compression circuit, in combination with a heat transfer fluid comprising 2,3,3,3-tetrafluoropropene, the content of polyol ester in the lubricating oil being less than or equal to 25%. Further, the use of said composition in methods for heating or cooling.
US10450485B2 Pressure sensitive adhesive sheet
A pressure sensitive adhesive sheet is provided which comprises a pressure sensitive adhesive layer formed of a pressure sensitive adhesive composition. The pressure sensitive adhesive composition contains an aliphatic polycarbonate and a pressure sensitive adhesive resin other than the aliphatic polycarbonate. The pressure sensitive adhesive sheet can be reduced in the adhesive strength at desired timing by a novel mechanism of action so that the release of an adherend becomes easy. The above pressure sensitive adhesive composition preferably contains an acid/base generator that generates an acid or a base by applying energy.
US10450483B2 Method for coating silicone rubber substrate
A method of coating a silicone rubber substrate, the method comprising (i) applying a coating composition comprising (a) about 50-80 wt % of a water-based silicone elastomer composition; (b) about 0.5-4.0 wt % of a silane adhesion promoter; (c) about 0.02-0.5 wt % of a silicone surfactant; and (d) about 10-50 wt % water to the silicone rubber substrate to form a coated substrate; and (ii) applying an acrylic material to the coated substrate.
US10450478B1 Epoxy resin, aqueous dispersion and water-borne epoxy coating composition comprising the same
The present invention provides an epoxy resin comprising: a polymer having a structure of a reaction product of a monomer of epoxy having at least two epoxide groups per molecule, a polyether monoamine, and an epoxidized oil. The present invention also provides an aqueous dispersion and a water-borne epoxy coating composition which comprise the epoxy resin. The present inventions are low in volatile organic compounds and have enhanced properties such as high hardness, high adhesion strength, high impact resistance and high corrosion resistance.
US10450475B2 Traffic marking compositions containing polyfunctional amines
Disclosed are aqueous coating compositions containing an anionically stabilized polymer, one or more polyfunctional amines acting as crosslinking agents, and a volatile base. Coating compositions can further include one or more additional copolymers, which may or may not be anionically stabilized, and/or additional additives, including pigments, defoamers, pigment dispersing agents, thickeners, surfactants, and combinations thereof. By incorporating one or more polyfunctional amines, such as those comprising recurring units derived from the reaction of one tri-glycidyl moiety and a single di-, or tri-functional amino monomer, or a combination of mono/bi, mono/tri, mono/tetra, bi/bi, bi/tri, bi/tetra, tri/tri, tri/tetra, and tetra/tetra functional amino monomers with a bi- or tri-glycidyl moiety, water wash-off resistance of the coating compositions which comprise paint formulations, can be increased.
US10450469B2 Transparent self-healing oleophobic and hydrophobic coatings
The present disclosure relates, in exemplary embodiments, to processes for preparing omniphobic coatings on a substrate. The disclosure further relates to substrates comprising an omniphobic coating comprising a fluoride ion encapsulated F-POSS.
US10450468B2 Surface treatment composition for coated steel sheet, surface treated plated steel sheet and method of production of same, and coated plated steel sheet and method of production of same
An aqueous surface treatment composition for coated steel sheet securing sufficient working adhesion while causing the formation of a surface treatment layer imparting excellent overhang corrosion resistance even without containing chrome, that is, a surface treatment composition containing a specific organic silicon compound, hexafluorometallic acid, a urethane resin having specific cationic groups, a vanadium compound, and an aqueous medium and sufficiently securing working adhesion while imparting excellent overhang corrosion resistance by the urethane resin having cationic groups and a total amine value of specific values is provided.
US10450467B2 Sanitation systems and components thereof having a slippery surface
The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (<2.5°), quickly restore liquid-repellency after physical damage (within 0.1-1 s), resist ice, microorganisms and insects adhesion, and function at high pressures (up to at least 690 atm). Some exemplary application where slippery liquid-infused porous surfaces will be useful include energy-efficient fluid handling and transportation, optical sensing, medicine, and as self-cleaning, and anti-fouling materials operating in extreme environments.
US10450464B2 Mixtures of coated pigments and fatty acid salts for dyeing PVC
The present invention relates to mixtures of pigments comprising at least one inorganic compound selected from the group of iron oxides, iron oxide hydrates, zinc ferrites, zinc oxides, magnesium ferrites and manganese ferrites, wherein the at least one inorganic compound is equipped with a coating comprising at least one hydroxide or oxide of magnesium or calcium and at least one calcium salt or magnesium salt of a fatty acid, to processes for production thereof, to the use thereof for coloring polyvinyl chloride (PVC) and to processes for coloring PVC and to PVC colored with such mixtures, and also to plastics products comprising such mixtures.
US10450458B2 Polymer composition, electronic device and method of manufacturing the same
The present disclosure relates to a polymer composition including eco-friendly materials, an electronic device and a method of manufacturing the same.The polymer composition according to an aspect of the present disclosure includes a thermoplastic resin at 30 to 70 parts by weight; an eco-friendly resin, including a bio-resin, at 1 to 50 parts by weight; and a silicone resin at 1 to 60 parts by weight based on the total weight of the polymer composition.
US10450451B2 Polypropylene composition for automotive interior applications
Polypropylene composition comprising a heterophasic propylene copolymer and a mineral filler, wherein said heterophasic propylene copolymer has a melting temperature in the range of 140 to 155° C., a xylene cold soluble content in the range of 20 to 35 wt.-% and a comonomer content of the xylene cold soluble fraction in the range of 18 to 95 wt.-%, wherein further the weight ratio between heterophasic propylene copolymer and the mineral filler is in the range of 2/1 to 4/1.
US10450450B2 Polyester block compatibilizer for polyethylene polypropylene blends
The present invention relates to a composition comprising polypropylene, polyethylene and a compatibiliser, wherein said compatibiliser is a block copolymer comprising a polypropylene block and a polyester block, said polyester being a non-aromatic polyester and having an average M/E ratio of at least 10, wherein M is the number of backbone carbon atoms in the polyester not including the carbonyl carbons and E is the number of ester groups in the polyester.
US10450449B2 PVC-free seals for twist crowns
The invention relates to a polymer compound for a PVC-free sealing insert for twist crowns, wherein the Shore A hardness of the polymer compound is between 50 and 90 and in the compressive deformation test analogous to ASTM D395-97 Method B at 70 DEG. C. the polymer compound exhibits a compression set of 30-90%.
US10450441B2 Solid state dye laser and methods for preparing the same
The invention provides a solid state dye laser and methods for preparing the solid state dye laser. The solid state dye laser includes a porous copolymer membrane of poly(vinylidenefloride-cohexafluoroproplyne (PVDF-HFP) and a laser dye. The laser dye is incorporated in pores of the copolymer membrane. The solid state dye laser is prepared using one of a phase inversion technique, a phase separation technique, and a breath figure technique.
US10450438B2 Purification of plasticizer and use thereof in a polymer production process and plant
The invention relates to purification of plasticizer, particularly for use in a polymer production process and plant. More particularly, the invention relates to purification of plasticizer, such as by gas stripping, for use in a process for in-line blending of polymer and plasticizer.
US10450437B2 Resin for thermoplastic polyurethane yarn using nanosilica and method for-manufacturing thermoplastic polyurethane yarn using the same
The present invention provides a resin for thermoplastic polyurethane (TPU) yarn using nanosilica and a method for manufacturing a thermoplastic polyurethane yarn using the same, where nanosilica having a particle size of 100 nm or less is added as a thickening agent for improving productivity and glossiness in the production of thermoplastic polyurethane yarns (preferably, mono- or multi-filament yarns using TPU alone), specifically in the production of thin TPU yarns, such as mono-filament TPU yarns having a denier count of 50 to 350 or multi-filament TPU yarns having a denier count of 50 or less without applying a coating of TPU to the surface of polyester or nylon yarns as disclosed in the prior art, thereby securing desired workability and properties and realizing continuous drawing of TPU yarns without thread breakage.
US10450433B2 Hydrophilic fluoroplastic substrates
Hydrophilic fluoroplastic substrates and methods of making hydrophilic fluoroplastic substrates from 4-acryloylmorpholine are disclosed.
US10450432B2 Puncture-healing thermoplastic resin carbon-fiber-reinforced composites and method of fabricating the same
A composite comprising a combination of a self-healing polymer matrix and a carbon fiber reinforcement is described. In one embodiment, the matrix is a polybutadiene graft copolymer matrix, such as polybutadiene graft copolymer comprising poly(butadiene)-graft-poly(methyl acrylate-co-acrylonitrile). A method of fabricating the composite is also described, comprising the steps of manufacturing a pre-impregnated unidirectional carbon fiber preform by wetting a plurality of carbon fibers with a solution, the solution comprising a self-healing polymer and a solvent, and curing the preform. A method of repairing a structure made from the composite of the invention is described. A novel prepreg material used to manufacture the composite of the invention is described.
US10450430B2 Adhesive composition for oil silicone rubber
An adhesive composition for oil bleeding silicone rubber comprising any of: (A) an alcohol-based organic solvent solution adding 45 to 120 parts by weight of organometallic compound and 2 to 10 parts by weight of water, based on 100 parts by weight of vinyltrialkoxysilane, (B) a solution in which 5 parts by weight or less, preferably 1 to 5 parts by weight, of 3-aminopropyltrialkoxysilane is added to the above alcohol-based organic solvent solution (A), or (C) a solution in which uncrosslinked silicone rubber dissolved beforehand in an organic solvent is added to the above alcohol-based organic solvent solution (A) or (B) in which the amount of the organometallic compound is changed to 5 to 20 parts by weight, at a ratio of 0.1 to 5 wt. %, based on the total solid matters of vinyltrialkoxysilane and the organometallic compound. The adhesive composition has excellent adhesion to various substrates, including metals.
US10450425B2 Super absorbent polymer and method for preparing the same
The present invention relates to a super absorbent polymer and a method for preparing the same. The present invention has features that it is possible to prepare a super absorbent resin that can have an improved centrifuge retention capacity (CRC) and a high absorbency under load (AUL) by controlling the shape and size of the chopper die holes during coarse pulverization of a hydrous gel phase polymer.
US10450423B2 Disintegratable porous organometaloxyde material
The present invention relates to disintegratable mesoporous silica materials, a method for producing the same, and uses thereof.
US10450418B2 Polymerizable composition comprising reactive silsesquioxane compound and aromatic vinyl compound
A polymerizable composition suitable for producing a molded article that can maintain a high refractive index and a low Abbe's number and can be restrained from dimensional changes due to a high-temperature thermal history has (a) 100 parts by mass of a specific reactive silsesquioxane compound, (b) 10 to 500 parts by mass of a specific fluorene compound and (c) 1 to 100 parts by mass of a specific aromatic vinyl compound. A cured product can be obtained by curing the polymerizable composition.
US10450417B2 Resin, composition, cured film, method for manufacturing cured film and semiconductor device
Provided is a resin capable of yielding a cured film with less warp and good uniformity, and of yielding a cured film (pattern) with less scum; a composition using the resin; a cured film; and a method for manufacturing a cured film and a semiconductor device. The resin is selected from polyimide precursor, polyimide, polybenzoxazole precursor, and, polybenzoxazole, and has a polymerizable group, and has a total content of a component with a molecular weight of 1,000 or smaller of 0.005 to 1.0% by mass.
US10450415B2 Polyamide compound, and method for producing same
To provide a polyamide compound having better properties than conventional polyamide compounds.A polyamide compound comprising a dicarboxylic acid unit represented by the following general formula (1) and a diamine unit represented by the following general formula (2). The polyamide compound of the present invention is characterized by having high energy absorption and high water-absorption resistance rate, and being amorphous (transparent).
US10450413B2 Silane compound containing perfluoro(poly)ether group
The present invention provides a perfluoro(poly)ether group containing silane compound of (Rf-PFPE)β-X—(CRakRblRcm)α  (1a) (RcmRblRakC)α—X-PFPE-X—(CRakRblRcm)α  (1b) wherein the symbols are as defined in the description.
US10450412B2 Use of additives to fine-tune the composition of carbonate units in a polymer formed by copolymerization of CO2 with epdxide: application to the synthesis of polycarbonate-based block copolymers and of telechelics
Embodiments of the present disclosure describe a method of making a polycarbonate, comprising contacting one or more cyclic monomers and carbon dioxide in the presence of one or more of a Lewis acid catalyst, an initiator, and an ionic liquid; and agitating, sufficient to copolymerize the one or more cyclic monomers and carbon dioxide to create a polycarbonate. Embodiments of the present disclosure further describe a method of controlling a polymer composition, comprising contacting one or more cyclic monomers and carbon dioxide; adjusting an amount of one or more of a Lewis acid catalyst, an ionic liquid, and an initiator in the presence of the one or more cyclic monomers and carbon dioxide, sufficient to selectively modify a resulting polycarbonate; and agitating, sufficient to copolymerize the one or more cyclic monomers and carbon dioxide to create the polycarbonate.
US10450410B2 Process for preparing polyester resins from polyethylene terephthalate and energy curable coating compositions
The present invention is directed to polyester resins which are prepared by depolymerizing virgin, scrap, recycled or reclaimed polyethylene terephthalate (PET) via an alcoholysis reaction with one or more polyhydric alcohols to form a depolymerization product and esterifying the depolymerization product with one or more polybasic carboxylic acids and/or anhydrides and optionally polyhydric alcohol to form a polyester polyol. The polyester may then be acrylated with acrylic acid to form a polyester acrylate resin. The polyester resins are then used in energy curable coating compositions or inks and in particular, the polyester acrylate resin is suitably used as a reactive binder/oligomer.
US10450409B2 Polymer powder and method for preparing same
Disclosed is a polymer powder having an average particle diameter of 20 μm to 300 μm, with a particle diameter of less than 10 μm of 10 mass % or less, and a particle diameter of greater than 300 μm of 10 mass % or less. Further, disclosed is a method for preparing a polymer powder, comprising: forming a melt of a polymer; introducing a supercritical fluid into the melt of the polymer to form a mixed composition; and spraying the mixed composition to prepare the polymer powder.
US10450407B2 Coated particles
An object of the present invention is to provide curing agent composite particles for epoxy resin, which are less likely to aggregate, and are excellent in storage stability and solvent resistance. Coated particles of the present invention comprise (A) curing agent particles for epoxy resin, and (B) an alkoxy oligomer, wherein the surfaces of the curing agents for epoxy resin particle are coated with the alkoxy oligomer.
US10450406B2 Fluorinated polyimide-based epoxy materials
A curing agent for curing an epoxy resin comprises a fluorinated central moiety covalently bonded to first and second imide-amine moieties, the first and second imide-amine moieties include amine terminal functional groups, wherein the amine functional groups of the curing agent, when applied to the epoxy resin, take part in curing reactions with ring molecules of the epoxy resin.
US10450403B2 Composition for polyurethane foaming, polyurethane foam and use thereof
A composition for polyurethane foaming, a polyurethane foam and a use thereof. The composition contains two different polyols with a polyethylene oxide ether structure and a polypropylene oxide ether structure, and a specific type of catalyst, flame retardant and water are added thereto; at the same time, the composition contains a small amount of a surfactant and other small molecular alcohols. The traits of the product are that it is pale yellow and transparent, and the product is not layered during long-term storage. The above-mentioned composition and polyphenylpolymethylene polyisocyanate (PAPI) produce a low-density polyurethane foam by means of a foaming machine. The foam has a good thermal insulation effect and a high rate of yield, and the foam has a flame retardant property, that is to say, same can be used for construction insulation, and can also be used for packaging a buffer material, has a good thermal insulation, adhesion and dimensional stability, and has a low odor during the process of construction, the foaming agents all use water, and do not contain chlorofluorocarbon substances that destroy the ozone layer and climate.
US10450402B2 Polyester polyol-containing polyurethane systems having improved hydrolytic stability
An isocyanate reactive composition for making a polyurethane foam includes a tertiary amine urethane catalyst comprising a di(C1-C4)alkyl fatty alkyl amine and a polyester polyol. The use of one or more of fatty alkyl tertiary amine serves to reduce hydrolysis of the polyester polyol in the isocyanate reactive composition.
US10450399B2 Porous material and methods related thereto
Disclosed herein is an aerogel made from a polyhydroxy benzene compound crosslinked with formaldehyde. The aerogel is dry and has a first volume and wherein the aerogel can be exposed to a liquid and be re-dried in a gas while retaining at least 70% of the first volume.
US10450398B2 High functionality polyesters and coatings comprising the same
A polyester prepared by free radical polymerization of an unsaturated polyester prepolymer, wherein the polymerization occurs primarily by reaction of the unsaturation of said prepolymer is disclosed. Coatings comprising the same are also disclosed, as are substrates coated at least in part with such coating.
US10450390B2 Metallocene compound, metallocene-supported catalyst, and method of preparing polyolefin using the same
Provided are a novel metallocene compound, a metallocene-supported catalyst, and a method of preparing a polyolefin using the same. The metallocene-supported catalyst according to the present disclosure exhibits a high polymerization activity even when the metallocene compound is supported on a support, thereby showing an excellent activity and preparing a polyolefin having a high molecular weight.
US10450387B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them
The present invention relates to a modifier and a modified and conjugated diene-based polymer including a functional group derived therefrom, and more particularly, provides a modifier including a compound represented by Formula 1, a modified and conjugated diene-based polymer including a functional group derived from the modifier and a repeating unit derived from a conjugated diene-based monomer, and methods for preparing them. In Formula 1, the definition of each substituent is the same as defined in the description of the invention.
US10450383B2 Carbonic anhydrase IX (G250) antibodies and methods of use thereof
The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
US10450382B2 Anti-complement C1s antibodies
The present disclosure provides antibodies that bind complement C1s protein; and nucleic acid molecules that encode such antibodies. The present disclosure also provides compositions comprising such antibodies, and methods to produce and use such antibodies, nucleic acid molecules, and compositions.
US10450374B2 Anti-galectin-9 antibodies and uses thereof
Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such anti-Galectin-9 antibodies may also be used to diagnose and/or to treat diseases associated with Galectin-9, such as autoimmune diseases and solid tumors.
US10450372B2 Anti-thyroglobulin T cell receptors
Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of thyroglobulin (TG), TG470-478. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the disclosure are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
US10450371B2 Monoclonal antibody and antigens for diagnosing and treating lung disease and injury
The present invention provides methods for diagnosing a patient with emphysema, COPD of lung injury caused by tobacco use by detecting the levels of EMAP II in a sample. Disclosed herein are the hypervariable regions for a rat monoclonal antibody that binds to a form of EMAP II. This disclosure also includes a polypeptide sequence included in EMAP II that is the target for the binding of the antibody to its target protein. This epitope serves as the basis for a humanized antibody that can be used to treat patients that suffer from pathologies that exhibit elevated levels of EMAP II expression.
US10450364B2 Hyperimmunized egg product for treatment of necrotic enteritis in poultry
In one aspect, the present invention is directed to a method for preventing or treating necrotic enteritis by administering a hyperimmunized egg product obtained from an egg-producing animal to an avian. The hyperimmunized egg product may contain an antibody specific to an antigen selected from the group consisting of Clostridium perfringens α-toxin, Clostridium perfringens elongation factor Tu (EF-Tu), Clostridium perfringens necrotic enteritis B-like (NetB) toxin, Clostridium perfringens Pyruvate: Ferredoxin oxidoreductase (PFO), and Eimeria tenella elongation factor 1-alpha.
US10450362B2 Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10450361B2 Methods related to CTLA4-Fc fusion proteins
The present disclosure provides, in part, methods for evaluating, identifying, and/or producing (e.g., manufacturing) a CTLA4-Fc fusion protein, e.g., abatacept. In some instances, methods herein allow highly resolved evaluation of abatacept useful for, inter alia, manufacturing abatacept, characterizing abatacept, identifying and/or confirming abatacept, monitoring the structure of abatacept, comparing abatacept preparations made over time or made under different conditions, and/or controlling the structure of abatacept.
US10450357B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10450351B2 Porcine circovirus type 3 immunogenic compositions and methods of making and using the same
A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analysis suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
US10450348B2 Antimicrobial agents and their use in therapy
The present invention provides an agent, or a composition containing an agent, for use in treating or preventing a bacterial infection in a subject, wherein said agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X1X2X3X4X5 (SEQ ID NO: 1) and wherein: X1 is a basic amino acid; X2 is an aromatic amino acid; X3 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X4 is any amino acid other than Proline (P), an acidic amino acid or an aromatic amino acid; and X5 is a basic amino acid or Proline (P); or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and compositions of the invention may be used as single agents. In other aspects of the invention agents and compositions of the invention may be used in conjunction with one or more additional active agents, such as antibiotics.
US10450346B2 Immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemia (CLL)
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to several novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US10450345B2 Method of isolation of polypeptide-aptamer-polymer conjugates
A method for purification of a target in a solution includes providing a target in a solution, the solution comprising one or more contaminants, providing a polymer conjugate in the solution, wherein the polymer conjugate is configured to specifically bind the target, incubating the solution at a first temperature to facilitate binding of the polymer conjugate to the target, providing an environmentally-responsive block copolymer in the solution, wherein the environmentally-responsive block copolymer comprises one or more of an ethylene oxide (EO), a propylene oxide (PO), or an EO/PO block copolymer, and heating the solution comprising the environmentally-responsive block copolymer and the polymer conjugate bound to the target at a second temperature to initiate a liquid-liquid phase separation, wherein the liquid-liquid phase separation produces an aqueous phase and a liquid polymer phase, and wherein the liquid polymer phase comprises the polymer conjugate bound to the target.
US10450344B2 Antibody-binding polypeptide, antibody-binding fusion polypeptide, and adsorption material
Provided are an antibody-binding polypeptide as set forth in any one of SEQ ID NOS: 1 to 18 and an adsorption material of an antibody or antibody derivative in which the antibody-binding polypeptide is immobilized on a water-insoluble carrier. These antibody-binding polypeptide and adsorption material have excellent antibody binding properties and selectivity, and also excellent alkali resistance and temporal stability.
US10450343B2 Synthesis of cyclic imide containing peptide products
The present invention relates to a method of synthesizing a peptide product comprising at least one cyclic imide group. Further, the invention relates to a peptide product comprising at least one cyclic imide group, which is substantially free from degradation products. The peptide product may be used as a reference material for the quality control of pharmaceutical peptides, particularly for the quality control of a GLP-1 agonist like exendin peptides.
US10450342B2 Method for solution phase detritylation of oligomeric compounds
Provided herein are methods for removal of monomethoxytrityl groups from oligomeric compounds comprising terminally linked monomethoxytrityl protected amino groups. The present methods differ from standard methods for 5′-dimethoxytrityl removal from oligonucleotides in that the present methods are performed at elevated temperatures and higher pH. In certain embodiments, the present methods provide detritylated oligomeric compounds having a reduced percentage of depurination relative to the same detritylated oligomeric compounds prepared using standard methods. In certain embodiments, the present methods provide an increased rate of detritylation compared to standard methods. In certain embodiments, the modification of the final detritylation step results in an improved yield.
US10450340B2 3′-deamino-3′-(2″-pyrroline-1″-yl)-5-imino-13-deoxyanthracyclines and methods of preparation
2-pyrrolino-13-deoxyanthracycline derivatives, medical uses thereof, and a process for making them. A 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline can be administered to a patient simultaneously or sequentially in amounts to produce a synergistic therapeutic effect with increased potency and efficacy, compared to the sum of the effects of each drug when administered alone. A composition or preparation of a 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline for producing a potent anticancer therapeutic effect is also provided.
US10450338B2 Non-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
US10450335B2 Antiviral oxime phosphoramide compounds
Compounds of Formula I: I and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.
US10450331B2 Functionalized cyanosilane and synthesis method and use thereof
The present teachings relate to a functionalized silyl cyanide and synthetic methods thereof. As an example, the method may include adding a raw material silane and a cyanide source MCN in an organic solvent to produce the functionalized silyl cyanide in the absence of catalyst or in the presence of a metal salt catalyst. The functionalized silyl cyanide may be used in the reactions that classic TMSCN participates in, to synthesize important intermediates (e.g., cyanohydrin, amino alcohols and α-amino nitrile compounds), with improved reactivity and selectivity. The cyanosilyl ether resulted from the nucleophilic addition of functionalized silyl cyanide to aldehyde or ketone may undergo intramolecular reaction under appropriate conditions to transfer the functional groups on silicon onto the other parts of the product linked to silicon. Such a functional group transfer process may increase the synthesis efficiency and atom economy, as well as afford products unobtainable using traditional TMSCN.
US10450330B2 Process for preparing a zirconium-based metal organic framework
There is provided a process for preparing a zirconium-based metal organic framework (Zr-MOF), the process comprising the steps (i) preparing a reaction mixture comprising zirconium ions, sulfate ions and at least one organic linker compound in an aqueous solvent; and (ii) heating the reaction mixture from step (i).
US10450329B2 Preparation of difluoro chelato borate salts
A process for preparing a difluoro chelato borate salt comprising an anion A of formula (I) wherein is a bidentate radical derived from a 1,2-, 1,3- or 1,4-diol, from a 1,2-, 1,3- or 1,4-dicarboxylic acid or from a 1,2-, 1,3- or 1,4-hydroxycarboxylic acid by abstracting the two H atoms of pairs of adjacent OH groups of the respective diol, hydroxycarboxylic acid or dicarboxylic acid. The process includes step (i) reacting (a) one or more BF3 sources; (b) a dihydric compound selected from 1,2-, 1,3- and 1,4-diols, 1,2-, 1,3- and 1,4-dicarboxylic acids, and 1,2-, 1,3- and 1,4-hydroxycarboxylic acids; (c) one or more second boron sources which do not contain F; and (d) one or more proton acceptors.
US10450327B2 Epidithiodioxopiperazine compound or its derivatives, and the use thereof
The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mimicking the activity of 2-Cys-Prx in its reduced form in the cells; a pharmaceutical composition for preventing or treating vascular diseases comprising an epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient; a drug delivery device for local administration including the pharmaceutical composition; and a pharmaceutical composition for inhibiting melanoma metastasis comprising the epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient.
US10450326B2 Thiazolopyrimidinone compounds and preparation methods and use thereof
The present invention provides structural details of a thiazolopyrimidinone compound, a preparation method thereof, and use thereof in the manufacture of a medicament for the treatment of central nervous system diseases.
US10450324B2 Methods useful in the synthesis of halichondrin B analogs
In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).
US10450323B2 Biologically active taxane analogs and methods of treatment by oral administration
The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
US10450321B2 [1,2,3]triazolo[4,5-D]pyrimidine derivatives
The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
US10450318B2 CXCR4 receptor antagonists
The invention generally relates to compounds of formula I which are antagonists of CXCR4. The invention includes pharmaceutically acceptable salts, compositions, methods of making the compounds of formula I, and methods of using the compounds of formula I for therapeutic indications.
US10450303B2 Biaryl piperidine amide compounds and methods of use thereof
The present application is directed to biaryl piperidine amide compounds, or pharmaceutically acceptable salts, solvates, and prodrugs thereof, and methods of use thereof.
US10450302B2 Methods of treating inflammation or neuropathic pain
Provided herein are methods of treating inflammation or neuropathic pain using an effective dose of a monoacylglycerol lipase inhibitor or a composition thereof.
US10450299B2 Substituted quinazoline derivatives as DNA methyltransferase inhibitors
The present invention relates to compounds of the following formula (I) and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
US10450297B2 Sulfonyl amide derivatives for the treatment of abnormal cell growth
The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
US10450291B2 Method for producing fluorine-containing cyclopropane carboxylic acid compound
The present invention provides an industrially applicable method for production of a fluorine-containing cyclopropane carboxylic acid compound useful as an intermediate for pharmaceutical and agrichemical products. A fluorine-containing cyclopropane monoester is obtained by: forming a fluorine-containing cyclic sulfate with the use of a fluorine-containing dial compound and sulfuryl fluoride (as a cyclic sulfuric esterification step); reacting the fluorine-containing cyclic sulfate with a malonic diester, thereby forming a fluorine-containing cyclopropane diester (as a cyclopropanation step); and hydrolyzing the fluorine-containing cyclopropane diester (as a hydrolysis step). The fluorine-containing cyclopropane carboxylic acid compound, such as fluorine-containing cyclopropane monoester or its salt, can be obtained with high chemical and optical purity by mixing the fluorine-containing cyclopropane monoester with an amine and subjecting the resulting salt of the fluorine-containing cyclopropane monoester and amine to recrystallization purification.
US10450283B2 3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: where R, L, X1, X2, X3, X4, Y1, Y2, Y3, and Y4 are described herein.
US10450273B2 N-(pyridin-2-yl)pyridine-sulfonamide derivatives and their use in the treatment of disease
The invention relates to heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.
US10450269B1 Compounds and uses thereof for the modulation of hemoglobin
Provided herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
US10450265B2 Method for producing amides or polyamides by using aromatic carbamates by way of isocyanates as precursors through catalyzed thermal processes and method for producing aromatic carbamate precursors from aromatic amines
The present invention is directed to a process for preparing amides or polyamides by replacing isocyanate starting materials of a catalyzed thermal reaction with aromatic carbamates. Through the catalyzed thermal process involving a non-isocyanate precursor of the present invention, efficiency for producing amides or polyamides can be significantly improved, and the impure side products produced from a side reaction of isocyanate can be greatly curtailed. Hence, amides or polyamides of high purity and yield can be achieved. The invention also relates to a process for preparing aromatic carbamates, the new non-isocyanate precursors for amides or polyamides.
US10450263B2 Benzo annulenes as antiviral agents
The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US10450261B2 Method for the homogeneous catalytic reductive amination of carbonyl compounds
The present invention relates to a method for the reductive amination of a carbonyl compound, comprising one or more carbonyl groups amenable to reductive amination, forming the corresponding primary amine, characterized in that the reaction is carried out in the presence of a homogeneously dissolved catalyst complex K, comprising at least one metal atom from Group 8, 9 or 10 of the periodic table, bearing a bidentate phosphane ligand, a carbonyl ligand, a neutral ligand and a hydride ligand, and also an acid as co-catalyst.
US10450257B2 Methods of synthesizing a prostacyclin analog
The present invention provides processes for preparing a prostacyclin analog of Formula I or a pharmaceutically acceptable salt thereof, wherein R10 is a linear or branched C1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods. The processes of the present invention employ reagents (e.g., the oxidizing reagent) that are less toxic that those used in the traditional methods (e.g., oxalyl chloride). Many of the processes of the present invention generate intermediates with improved e.e. and chemical purity; thereby eliminating the need of additional chromatography steps. And, the processes of the present invention are scalable to generate commercial quantities of the final compound.
US10450253B2 Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material
A simple production process is provided of a perfluoroalkyl compound that uses monohydroperfluoroalkane as a starting material, the perfluoroalkyl compound being an important intermediate of organic electronic materials, medicine, agricultural chemicals, functional polymer materials and the like. With monohydroperfluoroalkane is reacted a base and then a carbonyl compound to produce an alcohol having a perfluoroalkyl group. For example, potassium hydroxide is made to interact with trifluoromethane, and a reaction with a carbonyl compound is induced to produce an alcohol having a trifluoromethyl group.
US10450252B2 Method for hydrogenating carboxylic acids in order to form alcohols
Process for the continuous hydrogenation of a carboxylic acid (I) to an alcohol (II) by means of hydrogen at a temperature of from 100 to 300° C. and a pressure of 10 to 33 MPa abs in a reactor tube through which axial flow occurs and which has a fixed-bed catalyst which is fixed therein and comprises at least one element from the group consisting of Re, Co and Cu, and in which the carboxylic acid (I) to be hydrogenated is present in a liquid mixture (III) comprising the carboxylic acid (I), water and alcohol (II), where the mixture (III) has an acid number of from 0.2 to 25 mg KOH/g and comprises at least 15% by weight of water and at least 20% by weight of alcohol (II) and the flow velocity of the flowing liquid calculated on the basis of the geometric cross-sectional area of the empty, catalyst-free reactor tube is from 10 to 50 m/h.
US10450250B2 Production of farnesol
The present invention relates to an improved way for the production of farnesol.
US10450246B2 Compositions for control and inhibition of polymerization of vinyl aromatic monomers, and methods of use thereof
The present invention relates to an improved amine based additive composition for control and inhibition of polymerization of aromatic vinyl monomers, particularly of styrene comprising one or more quinone methide compounds, one or more phenolic compounds and further comprising at least one aliphatic tertiary amine containing —OH group in the alkyl chain. In one embodiment, the present invention also relates to method of use of presently provided composition. In another embodiment, the present invention also relates to method of controlling and inhibiting polymerization of aromatic vinyl monomers, particularly of styrene by employing presently provided composition. In still another embodiment, the present invention also relates to method of preparation of presently provided composition.
US10450241B2 Integrated propane dehydrogenation process
Processes and systems for the integrated production of propylene and an alkylate, such as cumene, may include feeding a hydrocarbon feedstock containing propane to a propane dehydrogenation reaction zone to convert a portion of the propane to propylene. The propylene is separated in a separation system to form a polymer-grade propylene stream, a low purity propylene stream, and a propane stream. The low purity propylene stream is then fed to an alkylation reaction zone where the propylene is reacted to produce an alkylated product and generate a low pressure steam. The low pressure steam may then be fed to the separation system as a heat source, integrating the dehydrogenation system and the alkylation system.
US10450238B2 Worm harvesting apparatus
A vermiculture unit comprises structural elements defining an interior fillable with organic substance and through which worms for converting the organic substance to environmentally compatible products migrate; a perforated surface for supporting the organic substance; and fixed walls extending upwardly from the perforated surface to a void area located below an uppermost edge of the structural elements, removal of worms from the interior that is below the void area being prevented by the fixed walls. An extractor is insertable into the interior via the void area, for extracting from the interior, solidified organic substance to which the worms have upwardly migrated, allowing grown worms to be separated from the extracted organic substance and collected. In one embodiment, the extractor is an openwork drawer member. In another embodiment, the structural elements are used for vermicomposting while an inclined surface receives worm processed byproducts downwardly discharged through the perforated surface.
US10450232B2 Cement formulation based on aluminium sulphate with a specific proportion of Ye'elimite systems
The present invention corresponds to a cement formulation based on sulfoaluminate comprising a specific Ye'elimite crystal proportion having enhanced mechanical resistance, setting and low CO2 emission features. A concrete obtained when mixing said formulation with water and gypsum is further described, having a superior performance at initial ages compared to concrete obtained from Portland cement.
US10450231B2 Process for preparing a composite material from an organic liquid and resulting material
The present invention relates to a method for preparing a composite material from an organic liquid, consisting of preparing a geopolymer by dissolution/polycondensation of an aluminosilicate source in an activation solution comprising said organic liquid. The present invention also relates to the thereby prepared composite material.
US10450229B2 Slim vermiculite board for construction finishing
The present invention relates to a slim vermiculite board for construction finishing comprising, to 100 parts by weight of fired vermiculite, 2.5-3.5 parts by weight of an additive and 100-120 parts by weight of a binder. The slim vermiculite board can help create a beautiful and luxurious interior by means of products having the natural patterns and diverse colors of vermiculite, does not produce construction waste and can be used as an agricultural soil conditioner. Also, the slim vermiculite board is light and easy to install, does not cause efflorescence, is deformation-free and eco-friendly, and has excellent deodorizing, antibacterial and fire-resistant properties and an excellent sound absorption coefficient.
US10450223B2 Coating solution for forming ultraviolet-absorbing film, and ultraviolet-absorbing glass article
To provide a coating solution for forming an ultraviolet-absorbing film which has mechanical durability such as abrasion resistance and which is little susceptible to deterioration of the ultraviolet-absorbing ability by use for a long period of time, and an ultraviolet-absorbing glass article having an ultraviolet-absorbing film formed by using such a coating solution, which has mechanical durability such as abrasion resistance and which is little susceptible to deterioration of the ultraviolet-absorbing ability by use for a long period of time. A coating solution which comprises a component derived from an epoxidized organooxysilane compound, a component derived from an organooxysilane compound which is a reaction product of a hydroxylated benzophenone compound and an epoxidized organooxysilane compound, and a component derived from an organooxysilane compound other than the above both organooxysilane compounds, and an ultraviolet-absorbing glass article obtained by using the coating solution.
US10450221B2 Hybrid sol-gel coated glass containers
A glass container and related methods of manufacturing and coating glass containers. An exterior glass surface of a glass container is coated with a hybrid sol-gel and heated to cross-link the hybrid sol-gel. The resulting cross-linked hybrid sol-gel coating on the exterior glass surface of the glass container has greater than 90% silicate-based material by weight.
US10450214B2 High optical quality glass tubing and method of making
A laminated or single layer glass cylinder and its method of making are disclosed. The laminated cylinder glass is a precursor component to enable making subsequent drawn tubing having high optical quality. The laminated cylinder glass may comprise a first layer of glass as a clad glass and a second layer of glass as a core glass. The second layer of glass may be bound to the first layer of glass. The second layer may have a higher CTE from about 5×10−7/° C. to about 100×10−7/° C. than the first layer of glass. The first layer and second layer of glass may have different softening points within about 200° C. of each other. In some embodiments, the first layer and second layer of glass may have different softening points from about 50° C. to about 200° C. of each other.
US10450213B2 Production of heavy brines by calcination of carbonates using plasma arc reactor
Embodiments relate to systems and methods directed towards arrangements of a preheater, a heat exchanger, a plasma recovery system, and at least one processing stage configured to use steam output of a calciner for heating incoming wastewater that is being processed.
US10450209B2 Stable salt-free polyaluminum chlorosulfates
A process for producing a polyaluminum chlorosulfate (PACS) includes adding an aluminum hydroxychloride (AHC) solution having about 38-43% basicity with (1) aqueous aluminum sulfate to form a solution and mixing a solid AHC with the solution to form an aqueous milky suspension or (2) a solid AHC and solid aluminum sulfate and adding water to the solid mixture to form an aqueous milky suspension, and maintaining the milky suspension for a period sufficient to allow the milky suspension to form a clear to slightly turbid solution including the PACS, the PACS having a basicity of 55 to 75%, the average molecular weight of the PACS is greater than or equal to 95 and less than or equal to 111, and salts present in the PACS comprise 0-1.0% sodium chloride by weight and 0-1.0% sodium sulfate by weight.
US10450202B1 Treatment of source water
There is provided herein a system and method for de-toxifing and de-scaling source water. In some embodiments, source water will be mixed with either an aluminum source or an iron source to separate endotoxins from acidic proteins and convert the naturally present bicarbonate in source water to carbon dioxide. Endotoxins and carbon dioxide will then be removed from source water by a stage of hydrophobic membranes to produce de-toxified and de-carbonated source water. Magnesium hydroxide will be mixed with the de-toxified and de-carbonated source water to form precipitates comprising foulants and sulfate. A recoverable and reusable amine solvent will also be used to induce efficient precipitation. Possible reuse applications for the treated source water by the inventive methods that minimize excessive uses of potable water may include hydro-fracturing of shale and sand formations and heavy oil recovery by steam injection.
US10450200B2 Tungsten oxide-type compound having a new crystalline structure and method for preparing same
The compound according to the invention is a compound of formula (1) Ax W1-yMOyO3, wherein A is chosen from the group comprising the Li, Na, NH4, K and H cations, and it is characterized in that x and y verify the relationships 0≤x≤1 and 0≤y≤0.5, and in that it has a crystalline structure of the hexagonal type with a base of WO6 octahedra, said structure having tunnels delimited by 6, 4 and 3 of said octahedra and oriented along the axis c.
US10450196B2 Process of fabrication of crystalline nanometric lithium transition metal phosphate
A process of fabrication of nanometric lithium transition metal phosphate with the general formula LiMPO4, where M denotes a metal ion or mixture of metal ions from a group comprising Fe, Mn, Co, and Ni, particularly lithium iron (II) phosphate, LiFePO4, by co-precipitation of nanometric powder from a boiling aqueous solution with the addition of organic liquid containing Li+, M2+, PO43− ions which after filtering, washing with water and alcohol, is characterised by the fact that a reducing agent in the amount of 10-100 mol. % in relation to transition metal ions is introduced to the solution containing at least one of the ions selected from a group comprising Li+, M2+, PO43−; and/or a reducing gas mixture is passed through the solution. At least one of the following agents is applied as a reducing agent: potassium iodide, ammonium thiosulphate, glucose, ascorbic acid, tin(II) chloride.
US10450193B2 Alcohol reformer for reforming alcohol to mixture of gas including hydrogen
Reforming alcohol is disclosed. Alcohol is introduced into a conduit of an alcohol reformer so that the alcohol flows through a catalyst stage within the conduit. The catalyst stage includes an alcohol reforming catalyst, and a heat transfer member comprising thermally conductive material. The heat transfer member is in thermal contact with the conduit and the alcohol reforming catalyst. Simultaneously, exhaust gas is introduced from an internal combustion engine into an exhaust channel. The exhaust gas in the exhaust channel contacts fins extending outward from the conduit so that heat from the exhaust gas is transferred through the fins, the conduit, and the heat transfer member to the alcohol reforming catalyst.
US10450184B2 Bridle for a riding animal, particularly for a riding horse
A bridle for a riding animal, particularly for a riding horse, includes at least one martingale, which is guided below the neck of the riding animal and is fastened on a girth. The fastening of the martingale takes place by way, of at least one pull-latch lock, which includes a lock body fixedly arranged on the girth and a tie rod, which can be removed from the same by way of the action of a transverse force and is in operative connection with the martingale. Falls due to the entanglement preferably of forelegs and martingales of the bridle can be prevented when using this bridle.
US10450183B2 Fluid management controller
A fluid management controller includes a processor, a wireless interface, and a memory. The wireless interface is configured to communicate between the processor and one or more fluid management components. The processor is configured to authorize control of the one or more fluid management components over the wireless interface. The memory is encoded with instructions that, when executed by the processor, cause the processor to provide dispense authorizations to the one or more fluid management components and record fluid dispense information from the one or more fluid management components in the memory.
US10450182B2 Liquid dispensing system
A liquid dispensing system for dispensing a liquid comprises an insulated housing comprising a top wall and a side wall mounted to the top wall, the side wall extending downwardly from the top wall to define an interior configured to receive a refill container comprising a liquid; a bottom surface mounted to the housing at a mounting interface and configured to enclose the interior of the housing; a sloped surface mounted within the interior of the housing and configured to induce the liquid within the refill container to flow toward a dispensing aperture through which the liquid is dispensed from the system; and a pump assembly in fluid communication with the interior of the housing, the pump assembly comprising a gas source and configured to deliver a gas from the gas source to the interior of the housing to apply pressure to the refill container.
US10450180B2 Multi-application oil funnel construction for refilling crankcases through a filling port
A tool kit comprised of multiple components from which select components may be assembled to provide a customized funnel construction with an adapter matched to a crankcase filling port of an internal combustion engine. Selective components of the kit may be arranged to provide an efficient and easily assembled oil filing device which provides improved access to crankcase filling ports of internal combustion engines. The components can easily be rearranged depending upon the design of the filling port of engine which is being serviced. The kit includes a common funnel section, one or more unique nozzle sections which in combination are compatible with two or more distinct unique adapters. This combination enables the use of a funnel of universal design for and with adapters of distinct design.
US10450179B2 System and method for synchronization of a container forming machine and a container processing machine in a container processing plant
A synchronization system for a container-processing plant, including a container-forming machine configured to form a container, the container-forming machine having a first rotating wheel for rotating the container about a first rotation axis; a container-filling machine operatively coupled to the container-forming machine and configured to fill the container, the container-filling machine having a second rotating wheel for rotating the container about a second rotation axis; and at least one electric motor configured to cause the first rotating wheel and the second rotating wheel to rotate, the synchronization system comprising: a position sensor provided in the container-forming machine and configured to detect a rotating position of the first rotating wheel and to generate a position detection signal; at least one control unit configured to: receive information associated with the position detection signal; synchronize the rotation of the second rotating wheel to the rotation of the first rotating wheel based on the information associated with the position detection signal; and synchronize the rotation of the container-forming machine and container-filling machine from a zero speed up to a full operating speed of the container forming machine at which processing operations are designed to be performed.
US10450178B2 Hand protective device for opening glass ampoules
The invention provides a cover of resistant elastomeric material capable of tightly containing and conforming to an ampoule. The elastomeric cover incorporates a longitudinal opening for insertion and removal of the ampoule. Flexing of the cover induces breakage of the ampoule at the desired location. The body of the ampoule, with its contents, can be easily removed, while the broken-off upper portion is retained in the cover for subsequent disposal. The device protects the hands from the sharp, broken edges of the opened ampoule.
US10450176B1 Barrel handling apparatus
A device for handling stacked barrels attaches to the end of a forklift truck. The opposing ends of the device deploys a pair of grip members to grasp opposing upper and lower edges of the barrel over at least about half of the circumference at the head or chime hoop. The grip members have an arcuate shape and pivot about a coupling holding them in rotary and parallel engagement with an upper and a lower support armature. The upper and lower support armatures are coupled at opposing ends to a common bracket. The common bracket is titled by a second actuator to rotate the grasped barrel from a vertical to horizontal orientation, such as for placement in or removal from barrel racks used for holding filled barrels during fermentation and/or aging. A support beam for the common bracket may be a horizontal frame that accepts forklift tines. The actuators of the device are connected to a common controller installed in the operator cabin of the forklift truck.
US10450174B1 Hoisting device and bolt for use therewith, method of making and using the same
A hoist ring assembly and related methods of lifting a load wherein the hoist ring assembly includes a bolt for securing the hoist ring assembly to the load and the bolt includes a tensile stress indicator for showing the tensile stress on the bolt when the bolt is tightened onto the load. The hoist ring assembly can further include a radio-frequency identification tag used for communicating information relating to the hoist ring assembly. The methods include using the tensile stress indicator to achieve and maintain a predetermined preload of the bolt, and using the radio-frequency identification tag to obtain historical recorded information relating to the hoist ring assembly.
US10450165B2 Elevator with a braking device
An elevator may include a brake apparatus such as a safety apparatus or a service brake, for example. The brake apparatus may be designed to generate a stepped braking force for braking an elevator car of the elevator. A plurality of brake cylinder assemblies may be configured so as to supply different braking forces. The brake cylinder assemblies may in some cases include a piston, a spring, and a brake pad. Moreover, a valve assembly may be utilized by one or more of the brake cylinder assemblies. Additional features of the brake apparatus may involve a compressor, a pressure accumulator, a pressure regulating valve.
US10450162B2 Electromagnetic brake control circuitry for elevator application
A brake system for an elevator car includes a multiple of brake segments for deceleration of the elevator car and a brake control circuit operable to control operation of each of the multiple of brake segments to passively sequence activation of each of the multiple of brake segments.
US10450160B2 Grating insert for rigging rope
An insert is provided for use on industry standard gratings to prevent wear and damage to rigging ropes passing through the insert.
US10450159B2 Vacuum within a pallet conveyor for a printing system
In one example, a pallet conveyor for a printing system is described, having a track, a pallet to support a print substrate and move on the track, and a vacuum mechanism to selectively apply a vacuum at the pallet. A boundary of the vacuum applied at the pallet is synchronized with an edge of the print substrate.
US10450157B2 Star wheel mounts
Examples described herein include a star wheel mount that includes a support element. The support element includes a first clip element coupled to a first end to engage a first mounting element on a media handler housing, and a second clip element coupled to a second end opposite the first end to engage a second mounting element on the media handler housing. The star wheel mount also includes a star wheel support axle coupled to hold a star wheel in a plane perpendicular to a surface of the media handler housing.
US10450153B2 Tracked radial stacker with wheels
A tracked, portable radial stacker for stockpiling bulk material is provided. It includes a linear conveyor having a rear portion and a front portion and being designed to carry bulk material from a low position adjacent the rear portion to a higher position adjacent the front portion. A continuous track system is provided which includes a frame to which the conveyor is mounted, the track system including a pair of driven, parallel tracks designed to contact the ground to convey the stacker from one position to another, and to be lifted off the ground when desired. A pair of wheels are mounted to the frame, the wheels being moveable between a raised position in which they do not contact the ground and a lowered position in which they lift the tracks off the ground as they engage the ground, enabling the conveyor to be moved about the ground on the wheels.
US10450147B2 Conveying system for conveyable and non-conveyable articles
A conveying system is disclosed. The conveying system may have a first conveying apparatus that conveys a first article to a first location. The conveying system may also have a second conveying apparatus that conveys a second article to a second location. The conveying system may have a frame, a chute connected to the frame, and a third conveying apparatus. The chute may convey the first article received from the first conveying apparatus to a discharge location. The third conveying apparatus, disposed below the chute, may convey the second article received from the second conveying apparatus to the discharge location. The chute may be movable relative to the to the third conveying apparatus, such that the first or second article may be selectively conveyed to the discharge location via the chute or third conveying apparatus, depending on the position of the chute relative to the third conveying apparatus.
US10450145B2 Lug loader
Embodiments provide an electric lug loader system. An electric lug loader may include a shaft assembly rotatably mounted to a frame that extends across a flow path. The shaft assembly may have shafts arranged radially around, and parallel to, the rotational axis of the shaft assembly, clamp members arranged along each of the shafts, support members arranged radially around the rotational axis and across the flow path, and electric drives coupled to the shafts. Conveyors may be coupled with the frame and spaced apart across the flow path upstream and/or downstream of the shaft assembly. Additional drives may be coupled with the shaft assembly and the conveyors. A controller may be configured to synchronize the drives to engage successive workpieces between the clamp members and the support members and deposit the workpieces onto a lugged conveyor. Other embodiments provide related methods and systems.
US10450144B2 System and method for transferring specimen containers between detection instruments
The present invention is directed to a system and method for transferring specimen containers between detection instruments. The method may include transporting a specimen container in a locator well to a container transfer station in a first automated detection apparatus; sensing the specimen container at the container transfer station using a first sensor; transferring the specimen container from the container transfer station of the first automated microbial detection apparatus to an automated loading mechanism of a second automated microbial detection apparatus; detecting that the specimen container is positioned over the automated loading mechanism of the second automated microbial detection apparatus using a second sensor; and releasing the specimen container onto the automated loading mechanism of the second automated microbial detection apparatus.
US10450142B1 Conveyor carrier cart
The present disclosure relates to a conveyor carrier cart. The conveyor carrier cart includes a main body, a pair of pivoting arms, and a folding mechanism. The main body defines a load carrying surface to support one or more objects disposed thereon. The pair of pivoting arms include a proximal end and a distal end. The proximal end pivotally connects each pivoting arm with the main body through the folding mechanism and the distal end connects with a guide member of a conveyor assembly. Each pivoting arm is configured to pivot between a deployed position and a retracted position. In the deployed position, the distal end of each pivoting arm engages the guide member of the conveyor assembly. In the retracted position, the distal end of each pivoting arm pivots about the folding mechanism to disengage from the guide member of the conveyor assembly.
US10450141B2 Composite belt profile
A composite belt may include a profile, and a belt. The profile may have a strip, and nodules. The profile may be attached to the belt such that each nodule extends out from the belt. The composite belt may be included in a cooking apparatus that may also include a housing, a heat source, and a drive roller.
US10450139B2 Modular storage system for large numbers of unique items for order fulfillment
An order fulfillment system stores any number of items in an item population. The item population includes any number of unique items. The order fulfillment system includes an input system, a storage system, and a packing system. The input system receives items for the population, prepares the received items for storage, and translates the items to the storage system. The storage system stores items in unique storage locations until the items are ordered by a customer of the order fulfillment system. The packing system prepares items orders, packages the items of the order, and sends the orders to the customer which ordered the items. The order fulfillment system also includes storage and fulfillment policies for determining storage locations and packing stations, respectively. Operators of the order fulfillment system can perform actions in the order fulfillment system to facilitate storing and fulfilling orders.
US10450137B2 Rotating vertical storage system for barrels
A rotating vertical storage system for barrels is provided. The system may comprise a first vertical support tower and a second vertical support tower. A first vertical support tower may have a first upper sprocket wheel and a first lower sprocket wheel with a first carrier chain rotationally coupled to the upper and lower first sprocket wheels. A second vertical support tower may have a second upper sprocket wheel and a second lower sprocket wheel with a second carrier chain rotationally coupled to the upper and lower second sprocket wheels. The system may further include a first cradle with a first end coupled to the first carrier chain and with a second end coupled to the second carrier chain. The cradle may comprise a plurality of barrel receiving valleys adapted to removably secure a plurality of barrels such as kegs.
US10450134B2 Extender for receptacle and method thereof
An extender formed from at least one flat piece of material that has straight edges, that includes a body structure formed by attaching a first edge of the at least one flat piece of material to a second, opposing edge thereof. The body structure includes a wall defining an interior space extending therethrough and at least one dynamic portion configured to be manipulated to create a first fold portion and a second fold portion that inwardly extend into the interior space. The body structure is configured to be inserted into a garbage can to extend a capacity of the garbage can. As the body structure is further inserted into the garbage can, the at least one dynamic portion facilitates a change in shape of the wall so that at least a portion of the wall becomes more tapered the further the body structure is inserted into the garbage can.
US10450133B2 Garbage can
A trash can includes a can body, a trash bag being in use and arranged in the can body, a trash inlet formed in the upper part of the can body, an upper cover for sealing or opening the trash inlet, a support frame being arranged in the can body and including a through hole, and spare trash bags being continuously stacked and then sleeving the outer side of the support frame.
US10450132B2 Container security system with oscillation device and method for performing container handling using container security system with oscillation device
A container security system is disclosed that includes force sensors and acceleration sensors attached to a lifting beam of a container handling device or to another part of a frame of the container handling device. The container security system also includes an electronics unit and an oscillation device attached to the lifting beam of the container handling device or to another part of the frame of the container handling device. The oscillation device creates oscillation of a container and contents of the container, and the container security system recognizes (i) a change in a condition of the container or the container contents as well as (ii) a change in an amount of the container contents between different container handling stages.
US10450125B2 Oral hydration system
A hydration system comprising: a fluid reservoir comprising a means for reversibly mounting the hydration system to a structure; a supply tube fluidly coupled to the reservoir at its distal end; a reversibly compressible chamber fluidly coupled to the supply tube; a mouthpiece proximate to or at a proximal end of the collapsible chamber; and at least two valves that regulate the flow of fluid through the hydration system, wherein a distal valve is positioned at a distal end of the chamber or along the supply tube and closes in response to compression of the chamber to reduce backflow of fluid into the reservoir during compression, and a proximal valve is positioned at the mouth piece, biased closed for regulating the delivery of fluid out of the mouthpiece and prevents or reduces air induction into the mouthpiece.
US10450121B2 Package for accommodating products
A package for accommodating products comprises a first portion hingedly connected to a first side of a rear panel, a second portion hingedly connected to a second side of the rear panel, the second side being opposite to the first side. At least one of the first and second portion comprises at least one recess adapted to accommodate a product. The first portion, the second portion and the rear panel at least partly form a receptacle adapted for accommodating said at least one recess. The first portion and the second portion are movable between an open state of the package in which the at least one recess is accessible to a user and a closed state of the package in which the at least one recess is inaccessible to a user.
US10450119B2 Films including a water-soluble layer and a vapor-deposited inorganic coating
Films including a water-soluble layer and a vapor-deposited inorganic coating are disclosed. The films exhibit enhanced barrier properties.
US10450116B2 Tagged products and tracking thereof using customizable data points
Container top assemblies and methods of fabrication thereof are provided. Product management and tracking of data for customizable data points is further provided. A container top assembly can include a cap comprising a central hole and a plurality of openings, a liner, and a radio frequency identification (RFID) tag embedded at least partially within the container top assembly.
US10450108B2 Method and device for automated evacuation of pharmaceutical tubes
In compounding pharmaceuticals at the outset, the medications are typically arrive in their mass produced form (pills, creams, syrups, etc.) and are individually packaged. Some packaging forms, particularly tubes, take an excessive amount of time to empty for the medication to be used in later compound medications. Presently in this industry, human workers will squeeze the medication out of each individual tube into large bucket containers for storage until the medication is ready for mixing. The disclosed invention provides a novel apparatus and method for emptying multiple tubes at a time with limited human interaction. The apparatus uses a roller and cap-pressing method that can empty several tubes at one time, significantly increasing efficiency. The apparatus is then connected with a novel software package which controls the operation of the device and can provide a counting mechanism for contract monitoring and predicting the lifespan of the device.
US10450106B2 Bag with zipper tape and method for producing same
A zipper tape includes a male belt-shaped base including a male base layer continuous with a male portion, and a female belt-shaped base including a female base layer continuous with a female portion. The male base layer and the female base layer are made of linear low-density polyethylene. A base film includes a sealant layer made of a resin containing polypropylene at 50 mass % or more with respect to the other resin component. A male seal layer and a female seal layer, which are bonded to the sealant layer, are made of a resin containing polyethylene at 50 mass % or more with respect to the other resin.
US10450099B2 Devices, systems, and methods for automatically printing and applying labels to products
Devices, systems, and methods for automatically printing and applying one or more label to at least one item to enable shipping of the at least one item by a carrier are provided. In some aspects, a movable label applicator device includes a printer for printing the one or more label onto a supply of labeling material, wherein the one or more printed label contains unique information associated with the at least one item. In some aspects, the device further includes an applicator for applying the one or more printed label to a surface of the at least one item, wherein the applicator is configured to apply multiple labels to the surface of the at least one item such that the multiple labels are removably stacked on top of one another.
US10450097B2 Device and method for feeding and dosing filter bags with infusion or extraction products
Described is a device for feeding and dosing infusion or extraction product of a machine (100) for making filter bags (S) containing the infusion or extraction product comprising a space (2) for containing infusion or extraction product defined by an outer lateral wall (3) and by an inner lateral wall (4) comprising openings (7) for the passage of the product; a feeding chamber (6) made inside the inner lateral wall (4), communicating through the openings (7) with the containment space (2) and equipped with an outlet (8) leading outside the containment space (2); a shutter (9), which is movable inside the feeding chamber (6) at least between a closed lower end position (P1), wherein it occludes the openings (7), and an open upper end position (P2), wherein it allows the passage of the product from the containment space (2) to the feeding chamber (6) through the openings (7) towards the outlet (8) to fill the filter bags (S) being formed.
US10450094B2 Film wrapping module for containers as a component of a packaging machine, and method thereof
A wrapping unit that wraps a container pack with a piece of film as it moves along a container-transport path includes a linear transporter having an electromagnetic linear drive. This linear transporter circulates movement elements in a common direction around a closed movement-path. Each of these movement elements has a gripping head arranged thereon.
US10450093B2 Device for electrical connection, method of assembling a female part of this connection device, superinsulating blanket and spacecraft
A device for electrical connection intended to connect a super-insulating mattress to a structural panel of a spacecraft, said connection device comprising: a conducting sleeve having an axis extending in a first direction, said sleeve comprising a device for axial fastening of the insulating mattress and a support, a conductive pin suitable for being arranged in said sleeve, an elastic element carried by said support, said elastic element being suitable for exerting a force on the pin in a direction substantially perpendicular to the first direction in order to press the pin against the sleeve. A method for assembling a female portion of a device for electrical connection to a super-insulating mattress, a super-insulating mattress and a spacecraft.
US10450084B2 Emergency locator transmitter activation device for enhanced emergency location performance
An aircraft avionics unit that enhances the emergency location capability of existing Emergency Locator Transmitters (ELTs). This aircraft avionics unit can be integrated with a wide range of existing ELTs and their existing aircraft interfaces by changes to a small number of the signal wires between the ELT and the aircraft systems and the addition of limited inputs from aircraft systems. This system requires no changes to either the current ELTs or the associated aircraft systems. The integrated system maintains the current ELT concept of operations while providing significantly enhanced ELT activation triggering with a low-impact, low-cost approach.
US10450082B1 Sensor-based guidance for rotorcraft
Disclosed herein is a method that comprises acquiring one or more images of an off-board signal source using a camera onboard a rotorcraft. The off-board signal source comprises a beacon array, which comprises at least two beacons. The method also comprises processing, using an image processor, the one or more images of the beacon array to identify one or more coded signals that are propagated from the off-board signal sour. The method further comprises decoding the one or more coded signals to identify information for providing guidance to an operator of the rotorcraft.
US10450080B1 Variable frequency power system for hybrid electric aircraft propulsion
A hybrid propulsion system for an aircraft is provided that includes a turbine engine, a first electric machine assembly connected to the turbine engine, a second electric machine assembly driven by the first electric machine assembly, and multiple third electric machine assemblies driven by the first electric machine assembly, wherein the multiple third electric machines provide a thrust output to propel the aircraft.
US10450079B2 Propulsive wing of an aircraft
A propulsive wing of an aircraft including at least two structural spars, upstream and downstream that extend in a wing span direction of the wing. A propulsion assembly includes at least two fans that are each driven by at least one gas generator. The at least one gas generator extends along an axis that is remote from the axis of rotation of at least one fan. At least one of the spars includes a first part and a second part between which the propulsion assembly is arranged. The first and second parts are interconnected by a rigid structure that is shaped to extend at least in part around the fans. The propulsion assembly is supported by the rigid structure.
US10450077B2 Flight termination for air vehicles
The present disclosure refers to a method and a related system of flight termination for air vehicles. The method and the system of flight termination for air vehicles involve deploying a parachute for flight termination of an air vehicle. A flight termination system, which in turn comprises at least one microcontroller unit that is connected to at least one parachute deployment system for deploying an air vehicle's parachute when a major emergency is determined during an air vehicle's flight.
US10450073B2 Seat track cover
A seat track cover for a passenger seat of an aircraft is positionable on a seat track. The seat track cover is mechanically coupled at a first end to a seat leg structure of the passenger seat via a pivot joint. The seat track cover is arranged substantially parallel to the seat track and takes up a covering position which covers a seat track located therebeneath when the passenger seat is in its working position. The seat track cover takes up a stowed position in a second state, wherein, in the stowed position, the seat track cover is pivotable out of the parallel plane with respect to the seat track via a pivoting movement about the pivot of the pivot joint. The transition from the covering position to the stowed position takes place via the pivoting movement about the first end of the seat track cover.
US10450069B2 Vehicle refrigeration equipment having a liquid heat rejection system
A refrigeration system includes an air chiller, a liquid coolant line that couples the air chiller with a central liquid coolant cooling system of a vehicle, a storage compartment stowage area having an interior for stowing a plurality of removable storage compartments, and a duct system that circulates chilled air from the air chiller through the storage compartment stowage area. The air chiller includes a compressor, a liquid-cooled condenser, an evaporator, and a tubing to circulate refrigerant. The liquid-cooled condenser transfers heat from the refrigerant to the liquid coolant which is then cooled by the central liquid coolant cooling system of the vehicle. The air chiller is situated parallel to the storage compartment stowage area along a plane perpendicular to a direction in which the removable storage compartments are removed and replaced. The duct system circulates chilled air from the evaporator through the interior of the storage compartment stowage area.
US10450067B2 Cover panel for an aircraft structural component
A cover panel for a core panel of a structural aircraft component includes a protection cover having an outer shape corresponding to the outer shape of the core panel and including at least one cutout aperture, and at least one fabric panel mounted to the protection cover and covering the at least one cutout aperture.
US10450063B1 Aircraft having VTOL, translational and traverse flight
An aircraft capable of Vertical Take-Off and Landing (VTOL) and traverse flight. The aircraft generally includes a fixed outer structure including at least a generally cylindrical wing having an internal body situated within the fixed outer structure. A space is defined between the internal body and the fixed outer structure. Within this space are one or more rotatable ring impellers that create(s) thrust sufficient to achieve lift for the aircraft.
US10450062B1 Versatile multirotor aerial vehicles
An aerial vehicle having a single wing is configured for vertical-flight and forward-flight operations. The wing has a substantially high aspect ratio. The aerial vehicle includes tilt motor assemblies disposed at a forward end and an aft end of a fuselage. The tilt motor assemblies are configured to orient motors and rotors vertically, horizontally, or at any angle between vertical and horizontal. A pair of parallel booms are mounted beneath the wing on either side of the fuselage. Each of the booms has at least one vertically oriented motor and rotor associated therewith, and a vertical fin extending thereunder. Additionally, a forward tilt motor assembly includes a rotatable extension that is deployed when the motor assembly is configured for vertical flight, enabling the aerial vehicle to land on the vertical fins and the landing rotatable extension.
US10450060B2 Elastomeric bearing with tab for thermocouple and system for use
A laminated elastomeric bearing has layers of elastomeric material and layers of metal. A tab is located on a periphery of one of the layers of metal and protrudes from the bearing. A thermoelectric device is coupled to the tab, and heat generated within the bearing during use is conducted to the tab and to the thermoelectric device, allowing for measurement of the heat.
US10450055B2 Methods and apparatus for a distributed aircraft actuation system
Methods, apparatus, and articles of manufacture for a distributed aircraft actuation system are disclosed. An example apparatus includes a collection engine to obtain first monitoring information corresponding to a first set of control surfaces of an aircraft, the first set including a first control surface on a first side of the aircraft and a second control surface on a second side of the aircraft, the second side opposite the first, and obtain second monitoring information corresponding to a second set of control surfaces of the aircraft, the second set including a third control surface on the first side and a fourth control surface on the second side. The example apparatus further includes a non-responsive component detector to determine if one of the control surfaces is non-responsive based on the first and the second monitoring information, and a command generator to deactivate the first set when the non-responsive component detector determines that the first control surface is non-responsive while the second set remains active.
US10450046B1 Separation apparatus for separating a first object from a second object
Aspects of the disclosure relate to terminating flight of a balloon that may include separating a connection between a balloon envelope and a payload of the balloon. In one example, a payload separation apparatus includes a first shaft configured to attach to the envelope, a second shaft configured to attach to the payload, a pair of arms, and a bracket arranged to secure the pair of arms to the first shaft. In another example, a system includes a flight termination assembly having a cutting edge configured to cut an opening in the envelope and a payload separation apparatus. The apparatus includes a first shaft configured to attach to the envelope, a second shaft configured to attach to the payload, a pair of arms, and a bracket configured to secure the pair of arms to the first shaft. The system also includes a controller configured to activate the cutting edge.
US10450045B2 Fuel supply apparatus of liquefied gas carrier and fuel supply method thereof
A fuel supply apparatus of a liquefied gas carrier includes: a compressor for compressing gas fuel into a high pressure; a compressed gas storage tank being filled with the compressed high-pressure gas fuel, for storing the gas fuel; and a decompressor for decompressing the high-pressure gas fuel drawn from the compressed gas storage tank into a pressure suitable to be used in a propulsion system, to supply fuel to the propulsion system. The gas fuel is at least one of a natural boiled-off gas which is naturally evaporated in the cargo tank, a forced boiled-off gas which is artificially evaporated, and a gas additionally supplied for the use of fuel. Further, the compressor is a multistage high-pressure compressor and the decompressor is a multistage decompressor.
US10450044B2 Electrical power distribution system, method for powering a corresponding task, propulsion system and method for a ship
This electrical energy distribution system comprises assembly of electrical energy generators each driven by a heat engine and supplying a distribution network; means for recovering the heat energy generated during the operation of the heat engines and for vaporizing a working fluid; steam turbine driven by the working fluid and associated with a generator connected to the distribution network for converting the recovered heat energy into electrical energy and at least one frequency converter arranged between the distribution network and an electrical load.It comprises means for controlling the frequency of the distribution network, where the flow rate of the vaporized working fluid is regulated to a maximum value.
US10450038B2 Continuous vertical tubular handling and hoisting buoyant structure
A continuous vertical tubular handling and hoisting buoyant structure has a hull, a main deck, an upper neck extending downwardly from the main deck, an upper frustoconical side section, an intermediate neck, a lower neck that extends from the intermediate neck, an ellipsoidal keel and a fin-shaped appendage secured to a lower and an outer portion of the exterior of the ellipsoid keel. The upper frustoconical side section is located below the upper neck and maintained to be above a water line for a transport depth and partially below the water line for an operational depth of the buoyant structure. An automated stand building system mounted to the hull is in communication with a controller and configured to make up the marine risers, make up casing, and make up drill pipe.
US10450035B2 Bicycle operating device
A bicycle operating device includes a support structure, a release member, a positioning ratchet and a position maintaining pawl. The release member is movable between first and second positions. The positioning ratchet has positioning ratchet teeth that establish predetermined positions. The position maintaining pawl is movable between a ratchet maintaining position and a ratchet releasing position. The position maintaining pawl includes a positioning portion, a holding portion, a release portion and a contact portion. The positioning portion moves away from the positioning ratchet, while the contact portion and the holding portion move toward the positioning ratchet teeth as the release member contacts and moves the release portion away from the release member as the release member moves in a releasing direction. The release portion moves away from the release member in response to movement of the positioning ratchet contacting and moving the contact portion away from the positioning ratchet.
US10450034B2 Bicycle operating device
A bicycle operating device has a base member, a holding member, a stopping member and a positioning member. The holding member is movable between a rest position and an operated position. The stopping member is movable in a first direction. The stopping member engages the holding member to prevent movement of the stopping member in the first direction while the holding member is in the operated position. The positioning member is movable relative to the base member in the first direction. The positioning member engages the holding member to prevent movement of the positioning member in the first direction while the holding member is in the rest position. The positioning member moves relative to the stopping member in the first direction while the holding member is in the operated position.
US10450032B2 Actuation device of the control cable of a bicycle derailleur
A bicycle gearshift cable control device that is rotatable about a control pin, in opposite angular directions, and has an indexer mounted coaxially to the control pin that defines a plurality of spaced apart, stable angular positions for the cable-winding bush. Elastic members that store elastic energy during a rotation of the control pin in one angular direction and release the stored elastic energy stored at the end of the rotation of the control pin are configured to cause a stroke recovery rotation of the control pin in the opposite angular direction during the release of the stored elastic energy. The stroke recovery rotation is smaller than the indexing angle that separates two adjacent stable positions of the cable-winding bush.
US10450025B2 Luggage carrier
There is provided an adapter for attaching an object to a luggage carrier. The adapter comprises a hook shaped portion engageable with a first attachment member of the luggage carrier, a latch configured to engage with a second attachment member of the luggage carrier and a release portion configured to release the latch from the second attachment member.
US10450013B2 Vehicular spoiler system to adjust airflow based on environmental factor
A vehicular spoiler system that adjusts airflow based on environmental factors, may include a spoiler device disposed to a vehicle to vertically pivotably rotate to be deployed or retracted, the spoiler device controlling an airflow when the spoiler device is deployed under predetermined operation conditions; and a controller configured to receive environmental information regarding a surrounding environment and to pre-store information regarding control of the spoiler device based on the environmental information, the controller performing control to deploy or retract the spoiler device based on local information when the local information, among the environmental information, is input.
US10450009B2 Panel locking device for vehicle cargo bed
A panel locking device for a vehicle cargo bed is configured to retain an openable gate-shaped panel so as to be upstanding at a closed position. The panel locking device includes a locking lever rotatably supported by a lever support portion provided at a first of the openable gate-shaped panel and a cargo bed panel adjacent to the openable gate-shaped panel, a movable hook rotatably coupled to a halfway portion of the locking lever, a first fixed hook provided to a second one of the openable gate-shaped panel and the cargo bed panel and configured to engage with the movable hook when the openable gate-shaped panel is located at the closed position, and a second fixed hook provided to the first one of the panels and configured to engage with the movable hook.
US10450008B2 Vehicle, in particular motor vehicle, with a tailgate
Vehicle, in particular a motor vehicle, which is equipped with a tailgate which can be pivoted on the rear of the vehicle. The tailgate can be pivoted by way of a pivoting device, around a pivoting axis between a closed position, in which a loading surface of the rear of the vehicle is defined, and an open position in which the loading surface of the rear side is open. In order to pivot the tailgate, the pivoting apparatus includes at least one pivoting arm on which the tailgate can be moved in a translatory manner and can be detachably held in place.
US10450006B2 Side-by-side all terrain vehicle
A side by side vehicle is disclosed having a vehicle frame having frame tubes extending from a front to a rear. A vehicle seat frame is positioned in a mid portion of the frame, and positions a seat frame at a raised position relative to the frame tubes. A powertrain is positioned rearward of the vehicle seat frame and is coupled to the vehicle frame. Side by side seats are supported by the seat frame; and one or more storage units are positioned under the side by side seats. The side by side vehicle also has a rear suspension comprising at least one rear alignment arm coupled to each side of a rear of the vehicle frame, where the alignment arms are coupled to the vehicle frame at front and rear connection points. A distance between the front connection points is greater than a distance between the rear connection points, and at least a portion of the powertrain is positioned between the front connection points of the alignment arms.
US10450004B2 Parking assistance device, parking assistance method, and parking assistance program
A parking assistance device includes: an imager that captures an image of a surrounding of a vehicle; a display unit that displays a guidance image for guiding the vehicle from a parking start position to a target parking position; a parking guidance creating unit that creates parking guidance information showing a parking route, based on basic information including the captured image by the imager, the parking start position, and the target parking position; a moving area determining unit that determines a moving area based on the parking guidance information, the moving area being an area in which the vehicle can move; and a display controller that displays, on the display unit, an image showing the moving area and an image prompting to confirm that there is no obstacle such as a parked vehicle in the moving area, together with the guidance image based on the parking guidance information.
US10450003B2 Parking assist device and parking assist system
A parking assist device for assisting parking of a vehicle, includes: a detecting unit that detects whether there is any obstacle and detects available parking areas for the vehicle, on the basis of a taken image of the surrounding area of the vehicle; and a selecting unit that selects an available parking area where the vehicle is parked with low risk of contact with the obstacle, from the detected available parking areas, on the basis of whether there is the obstacle.
US10450002B2 Automated watercraft transfer
Various examples of transferring a watercraft between land and water are disclosed. When a vehicle receives a transfer signal, the vehicle locates a launch ramp, and the vehicle moves to the launch ramp. A trailer attached to the vehicle moved into the water using the launch ramp, such that a watercraft can be transferred between land and water via the trailer.
US10450000B2 Electric power steering system
An electric power steering system includes a vehicle speed sensor configured to detect a vehicle speed, a motor driving circuit configured to supply power to an electric motor, a main power supply and a capacitor that can supply power to a driving circuit, a charging circuit configured to charge the capacitor based on the main power supply, and an ECU for power source control that controls the charging circuit. The ECU for power source control drives the charging circuit to charge the capacitor only when the vehicle speed is lower than a first predetermined value and an inter-terminal voltage of the capacitor is lower than a second predetermined value.
US10449998B2 Apparatus for introducing an auxiliary torque into a steering shaft of an electromechanical power steering system
An apparatus for introducing an auxiliary torque and/or an additional steering angle into a steering shaft of an electromechanical power steering system may comprise a gearwheel that is attached fixedly on the steering shaft so as to rotate with the steering shaft and that is operatively connected to a drive element of a drive motor for driving the gearwheel. The apparatus may further include a sensor that is connected fixedly to the steering shaft so as to rotate with the steering shaft. So that the attachment of the sensor can take place with less complexity and use less installation space as far as possible, the sensor and the gearwheel may be connected to one another at contact faces.
US10449990B2 Clamp mechanism
A steering column assembly includes a clamp mechanism comprising a clamp pin that passes through an opening in a shroud of the steering column assembly and an opening in a bracket that supports the shroud of the steering column assembly. A first reaction member is secured to one end of the pin and a second reaction member secured to another end of the clamp pin, the reaction members defining a length of clamp pin between them that passes through the opening in the shroud and the opening in the support bracket. A cam mechanism has a fixed part and a moving part, each having an opening through which they are threaded onto the clamp pin between one of the reaction members and the support bracket. The moving cam part is connected to a lever and free to rotate around the clamp pin as the lever is rotated, the fixed cam part being prevented from rotation around the clamp pin, a cam surface of the fixed part being in contact with a cam surface of the rotating part and configured such that rotation of the rotating cam part is converted into an axial movement of the fixed cam part resulting in a change in the overall length of the cam mechanism. The cam steering column assembly is configured so that the increase in length of the cam mechanism when in a clamped position causes the bracket to be clamped to the shroud, and the assembly further comprising a damping member that is fixed to at least one of the clamp pin, the fixed cam and the moving cam so that the resilient damping member is compressed as the cam mechanism moves to the unclamped condition so as to damp the movement of the cam mechanism.
US10449986B1 Transport cart for ballast block
A transport cart for transporting a ballast block upon a ground surface by a user. The ballast block has a front, rear, top, bottom, and has a plurality of fastening openings on the top. The transport cart has a main frame having a pair of parallel side members, a wheel assembly, a pair of overhead frames attached between the side members, and a cross member attaching the overhead frames. A lifting mechanism is attached to the cross member and includes a lifting arm extending parallel to the side members, and a pair of engagement plates attached to the lifting arm. The engagement plates fasten to the fastening openings on the top of the ballast block. The lifting arm is raised by rotating a handle to raise the block above the ground surface, whereupon the ballast block may be moved along the ground surface using the wheel assembly.
US10449984B2 Space-saving loading equipment
An apparatus for loading and unloading a cart into and from a chamber of a housing. The apparatus is movable between a first, collapsed configuration and a second, expanded configuration. The apparatus includes a user portion and a chamber portion engagable with the housing. The chamber portion is movable relative to the user portion. An attachment assembly selectively attaches the apparatus to the housing. At least one cart locking device selectively locks the cart to the apparatus. When the at last one cart locking device locks the cart to the apparatus, the cart is removed from the chamber when the apparatus moves from the first, collapsed configuration to the second, expanded configuration. The cart is inserted into the chamber when the apparatus moves from the second, expanded configuration to the first, collapsed configuration.
US10449983B2 Method for commanding a railway level crossing protection system
A method for commanding a railway level crossing protection system comprising: a) activating a railway signal preventing a train from driving beyond a level crossing; b) detecting an incoming train approaching the level crossing and measuring a speed of said incoming train; c) calculating a waiting time, as a function of the train's measured speed; d) waiting until expiration of the calculated waiting time and, once said waiting time expires, sending an order to commute the protection system into the protected state; and e) querying the state of the protection system and if said protection system is found to have commuted into the protected state, deactivating said railway signal, and maintaining said railway signal in the activated state otherwise.
US10449982B2 Wireless communication system, wireless communication device, wireless communication method, movable fence control system, communication device, and movable fence device
One of the first and second wireless communication devices is disposed in a mobile object, and the other is fixed. The first wireless communication device includes a wireless transmission/reception unit that transmits data to the second wireless communication device and performs wireless transmission and reception in order to detect whether the mobile object is stopped. When, in a first mode for transmitting data to the second wireless communication device and determining whether the reception strength of a received signal is equal to or greater than a first value, the first wireless communication device detects that the reception strength is equal to or greater than the first value, the first wireless communication device stops the transmission of data to the second wireless communication device, exits the first mode, and transitions to a second mode for determining whether the mobile object is stopped.
US10449981B2 Apparatus and method for dynamically configuring wireless sensor relay network for monitoring train activity
An apparatus for dynamically configuring a wireless sensor relay network for monitoring train activity according to the present invention includes a plurality of wireless sensors that wirelessly transmit sensor data obtained by measuring heat and vibration of a train running unit, a plurality of coordinator units that are located in train cars, and receive the sensor data from one or more wireless sensors located within the same train car, a plurality of wireless relay units that are located in the train cars, form a wireless sensor relay network with the wireless relay unit located in a neighboring train car, and transmit the sensor data received from the coordinator units, and a gateway unit that receives the sensor data from the plurality of wireless relay units through the wireless sensor relay network, and transmits the received sensor data to a control center.
US10449971B2 Travel control device
In a case where automatic lane change control is performed, a traveling lane and another lane as a lane change destination are displayed on a display unit based on lane change information, and a guide indication of a lane change starting position or a lane change finishing position is displayed on the displayed traveling lane or the displayed another lane.
US10449969B2 Parking path calculation device, parking assist device and parking path calculation method
Provided are a parking path calculation device, a parking assist device, and a parking path calculation method, which are capable of improving a degree of freedom of calculating a parking path. A parking path calculator calculates a virtual parking position establishing a predetermined positional relationship with a parking end position when an own vehicle moves backward from an own vehicle position to a parking end position at a minimum turning radius, and calculates, depending on a positional relationship between the virtual parking position and the parking end position, a parking path on which steered wheels are to be steered to cross a neutral position thereof at a time of guiding the own vehicle.
US10449968B2 Methods and apparatus for adaptively assisting developmentally disabled or cognitively impaired drivers
Methods and apparatus for adaptively assisting developmentally disabled or cognitively impaired drivers are disclosed. An apparatus comprises a user interface. The user interface is to present first navigation data in a first mode to assist a driver in guiding a vehicle from a current location to a destination location. The user interface is further to present second navigation data in a second mode to assist the driver in guiding the vehicle from the current location to the destination location. The second navigation data is adapted relative to the first navigation data based on driver assistance data associated with the driver.
US10449966B2 Method for reducing nitrogen oxide emissions of a diesel vehicle
A method for reducing nitrogen oxide emissions of a diesel vehicle. In this context, first state variables of the diesel vehicle are measured with the aid of sensors of the diesel vehicle, and using an arithmetic unit, it is ascertained, as a function of the first state variables, if the nitrogen oxide emissions are exceeding a predetermined threshold, or using the arithmetic unit, it is predicted, as a function of the first state variables, if the nitrogen oxide emissions will exceed the predetermined threshold. If exceedance of the threshold is calculated or predicted, then an intervention in the current torque demand of the diesel vehicle and/or an intervention in the current transmission ratio or setting of a transmission of the diesel vehicle is ascertained by the arithmetic unit; the intervention contributing to a reduction in the nitrogen oxide emissions to a value below the threshold.
US10449964B2 Method and system for controlling sailing stop in vehicle
Variator (20) and forward clutch (Fwd/C) disposed in series are provided between engine (1) having starter motor (15) and driving wheel (7). Sailing stop control that, on the basis of satisfaction of sailing entering condition, interrupts power transmission by frictional engagement element (Fwd/C), stops engine (1) and performs coast-travel is performed. When sailing entering condition is satisfied, coast-travel is started with rotation stop timing of variator (20) being delayed with respect to rotation stop timing of engine (1). When accelerator pedal depression operation intervenes after start of coast-travel, engine (1) is restarted by starter motor (15). When judged that input and output rotation speeds of frictional engagement element (Fwd/C) become synchronization rotation speed after restart of engine (1), frictional engagement element (Fwd/C) is reengaged. Shift response from coast-travel to normal travel is therefore improved at change-of-mind at which sailing quitting condition is satisfied during progress of automatic stop of engine.
US10449960B2 Control system and control method for determining a likelihood of a lane change by a preceding vehicle
A control system that is suitable for use in a host motor vehicle (10) is configured and intended for detecting (S100) another motor vehicle (20), using the road, located in front of the host motor vehicle (10) by means of the at least one surroundings sensor, determining (S106) a lateral movement of the other motor vehicle (20) relative to a lane (12, 16) in which the other motor vehicle (20) or the host motor vehicle (10) is present, and computing (S108) a movement-based likelihood of a lane change by the other motor vehicle (20), based on the determined lateral movement of the other motor vehicle (20). In addition, the control system is configured and intended for determining (S110, S112, S114) an instantaneous traffic situation in accordance with the surroundings data obtained by means of the surroundings sensor, computing (S116) a traffic situation-based likelihood of a lane change by the other motor vehicle (20), based on the determined instantaneous traffic situation, and computing (S118) an overall likelihood of a lane change by the other motor vehicle (20), based on the movement-based likelihood and the traffic situation-based likelihood.
US10449955B2 Automatic parking system and automatic parking method
An automatic parking system includes a sensor detecting parking areas depending on a size of a subject vehicle and a controller controlling the subject vehicle to be parked in an optimal parking area among the parking areas, in which the sensor may detect the parking areas in consideration of a length and a width of the subject vehicle and detect a spaced distance from surrounding vehicles positioned on a side of the subject vehicle in the optimal parking area and the controller may calculate a moving path between a current position of the subject vehicle and the optimal parking area and compare a predetermined reference distance and the spaced distances to control the subject vehicle.
US10449952B2 Hybrid vehicle
A hybrid vehicle is equipped with a drive unit, and an automatic transmission. The automatic transmission includes engagement elements that can transmit power between the drive unit and driving wheels. The drive unit includes an engine, a first motor generator, a second motor generator, and a planetary gear mechanism. The hybrid vehicle is further equipped with a mechanical oil pump and an electrical oil pump, and a controller. The controller continues operating the electrical oil pump while the internal combustion engine is not in operation after the internal combustion engine is stopped as a result of a system stop operation by a user while the vehicle is running at a vehicle speed equal to or higher than a predetermined value.
US10449951B2 Drive mechanism for a motor vehicle, and method for operating a drive mechanism for a motor vehicle
Drive mechanism (1) for a motor vehicle (6), comprising a dual clutch transmission (10) that includes a first powertrain (13), which can be connected to a first drive unit (2) via a first clutch (21), and a second powertrain (14), which can be connected to the first drive unit (2) via a second clutch (22), the first powertrain (13) being securely coupled to a second drive unit (3); when shifting gears in the dual clutch trans-mission (10), the second drive unit (3) supplies a predefined drive torque.
US10449950B2 Control apparatus for vehicle and control method for vehicle
A control apparatus for a vehicle includes an electronic control unit that is configured to set a value of a target generated voltage of the generator. The electronic control unit is configured to execute power generation control to control a generated voltage of a generator. The electronic control unit is configured to maintain a value of the generated voltage in the power generation control to be constant during an upshift gear change when the upshift gear change control of a transmission is executed while the lock-up clutch control is executed during deceleration of the vehicle. The electronic control unit is configured to increase the value in the power generation control during the downshift control to the value of the target generated voltage at a first specified rate when a downshift gear change of the transmission is executed while the lock-up clutch control is executed during the deceleration.
US10449949B2 Vehicle control apparatus
A vehicle control apparatus includes: a transmission shifting control portion configured to implement a shifting action of a step-variable transmission, by controlling a releasing action of a releasing coupling device and an engaging action of an engaging coupling device; a torque control portion configured, during the shifting action of the step-variable transmission, to implement a feedback control to control an input torque inputted to the step-variable transmission, such that a value representing a state of a rotary motion of an input rotary member of the step-variable transmission coincides with a target value dependent on a degree of progress of the shifting action; and a backup control portion configured, when it is determined that the drive wheels are slipped, to inhibit the feedback control, and to compensate a transmitted torque to be transmitted through an initiative coupling device, such that the shifting action is facilitated by compensation of the transmitted torque.
US10449937B2 Electronic brake system and control method thereof
Disclosed herein is an electronic brake system, which includes at least one or more valves provided to control a hydraulic pressure delivered to wheel cylinders provided in wheels, a pressure measurer configured to measure the hydraulic pressure delivered to the wheel cylinders provided in the wheels, and a controller configured to open at least one or more valves that deliver the hydraulic pressure to a corresponding wheel cylinder and close at least one or more valves that deliver the hydraulic pressure to the remaining wheel cylinders other than the corresponding wheel cylinder when the at least one or more valves are detected as being opened or closed a predetermined number of times or more during a predetermined time period, and synchronize the measured hydraulic pressure with a hydraulic pressure of the wheel cylinder having all of the at least one or more valves open.
US10449934B2 Pedal displacement sensor and electronic brake system comprising the same
Disclosed herein are a pedal displacement sensor and an electronic brake system including the pedal displacement sensor. The pedal displacement sensor includes a magnet to be movable, a first electrical steel plate including one end spaced apart from an upper side of the magnet and one surface to face the magnet, a second electrical steel plate including one end spaced apart from a lower side of the magnet and the other end spaced apart from the other end of the first electrical steel plate, and a magnetic sensor to measure a magnetic flux between the other end of the first electrical steel plate and the second electrical steel plate.
US10449931B2 Lock system and apparatus for a motor vehicle with secondary energy storage and transmission for emergency operation
A lock system for access authorization in a motor vehicle, having a first device which has at least two states and is embodied as a control device, and having an associated second device which is embodied in the manner of an electronic key, an ID signal transmitter, a chip card or the like. The two devices have transmitters and/or receivers for electromagnetic signals. At least one of the signals transmitted between the second device and the first device is an encoded operating signal for authenticating the second device, with the result that after a positive evaluation of the transmitted operating signal when the second device is authorized it is possible to bring about a change in the state of the first device.
US10449926B2 Seatbelt assist device and vehicle seat
Provided is a belt assist device having a compact configuration and being configured to move a seatbelt to an easily reachable position. A vehicle seat includes a belt assist device attached to a lateral portion of a seat back and configured to move a portion of a seatbelt placed on the lateral portion to the easily reachable position. The belt assist device includes a rotary member attached to a recessed housing portion of the lateral portion via a rotary shaft and configured to rotate up and down between a housing position at which the rotary member is housed in the seat back and a protruding position at which the rotary member rotates to protrude forward of the seat back to push out a portion of the seatbelt. The rotary member is disposed forward of a belt guide provided at the periphery of an upper end of the seat back.
US10449925B2 Deflector for reduced head injury criterion
An air deflector for a vehicle cowl is provided. The air deflector includes a first side extending parallel to a longitudinal axis of the vehicle, an attachment portion configured for attaching the air deflector to the vehicle, resulting in an attached configuration, a second side opposite and parallel to the first side, wherein when in the attached configuration, the second side faces inward toward a centerline of the vehicle, and a hinged portion positioned on the first and/or second side such that a force applied at a top portion of the air deflector in the attached configuration causes deformation of the air deflector along the hinged portion.
US10449923B2 Roof airbag for vehicle
A roof airbag for a vehicle may include an inflator at a first end portion of a front and a rear end portions of a sunroof frame configured to discharge deployment gas when activated; a reinforcement member connecting a first and a second side of the sunroof frame at a position between the front and the rear end portions of the sunroof frame; and an airbag cushion at the first end portion of the front and the rear end portions of the sunroof frame in a folded state, and configured with a first chamber configured to cover from the first end portion of the front and the rear end portions of the sunroof frame to a position before reaching the reinforcement member and a second chamber configured to cover from the reinforcement member to the second end portion of the front and the rear end portions of the sunroof frame.
US10449922B2 Air-bag
Provided is an air-bag capable of further reducing damage value to a passenger and limiting the amount of use of inflator gas by limiting an excessive increase in the internal pressure of the air-bag upon contacting the passenger while increasing the speed of deployment in a passenger protection area. The air-bag includes a main chamber and a sub-chamber that are connected via a communication portion, wherein the communication portion or a region adjacent to the communication portion is configured of a multilayer structure portion comprising three or more layers.
US10449916B2 Method for improving fuel economy by influencing driver behavior
A vehicle computer system (e.g., on-board vehicle computer system) obtains a fuel economy performance goal for a vehicle (e.g., an engine speed goal or a vehicle speed goal) that is based on a configuration of the vehicle; calculates a count of events in which a current value exceeds the goal; compares the count of events with a threshold count; and generates one or more notifications based at least in part on the comparison (e.g., for display on an operator interface). The vehicle computer system also calculates an engine speed and a vehicle speed score for a driver of the vehicle based at least in part on comparisons of current speeds with the speed goals. Scoring and other data may be displayed or stored for further processing.
US10449915B2 System for transmitting a piece of information to a subunit
A system for transmitting a piece of information to a subunit, including at least one connection position and at least one subunit, the at least one connection position being configured for accommodating a subunit, and the at least one connection position including at least one coding lug which is configured for engaging into a corresponding recess on a subunit, the arrangement of the at least one coding lug coding the piece of information to be transmitted, and the at least one subunit having at least one recess which is configured for contactlessly detecting the presence of a coding lug in a recess.
US10449913B2 Portable device having a changeable illuminated display and communications platform
The present invention relates generally to illuminated display devices and methods of displaying indicia, advertisements, etc. on a changeable illuminated display. The display device comprises a frame structure, a plurality of openings formed in the frame structure, the plurality of openings comprising first and second open spaces disposed at top and bottom positions, respectively, of the frame structure, and the plurality of openings further comprising a third open space disposed between the first and second open spaces. The display device further comprises a compact image display device operable to display an image, the compact image display device held and positioned relative to the frame structure such that first, second, and third different portions of the image, when displayed by the compact image display device, are visible through the plurality of openings first, second, and third open spaces, respectively. Additionally, control circuitry is coupled to the compact image display device.
US10449908B1 Vehicle garment hanging device
A device is removably secured within a vehicle and allows multiple hangers to be properly positioned on the device for clothing transport. The device uses a support bracket that straddles a grab bar of the vehicle. A rod passes through a pair of aligned slots on the support bracket and has end caps thereon to prevent hangers from sliding off of the rod. The rod also passes through a slot on a ladder bracket, this bracket having a relatively flat base plate that abuts against an interior surface of the vehicle, such as the roof surface, a window, or the door frame vehicle in order to stabilize the rod in a generally horizontal orientation.
US10449907B2 Storage compartment and hanging storage module having illuminated tab
A vehicle storage compartment includes a support structure, power contacts, and a hanging storage module such as a file folder supported on the support structure and electrically coupled to the power contacts. The module includes a storage pocket, support arms supporting the pocket and configured to be supported on the support structure, and electrical conductors coupled to the contacts. The module further includes a tab comprising a light source and a user input sensor, wherein the light source illuminates storage the module when the user input sensor detects a user input.
US10449904B2 Safety platform
A safety platform includes a sliding frame capable of attaching to a unit, and a deck having at least one deck side. The deck is movable between a stowed position and a deployed position. The safety platform further includes a stair, ladder, or ramp operatively connected to the at least one deck side and capable of extending therefrom, at least one vertical post member connected to the deck, a handrail operatively connected to the at least one vertical post member, and a vertical toeboard operatively connected to the at least one deck side, excluding a portion of the deck operatively connected to the stair, ladder, or ramp. The handrail is configured to extend along and parallel to an outer side of the stair, ladder, or ramp, and the at least one deck side, excluding a portion of the deck operatively connected to the stair, ladder, or ramp.
US10449901B2 Display device and rear-view mirror module including the same
A display device may comprise a transmittance control structure having a variable transmittance and a mirror type display panel disposed on a rear surface of the transmittance control structure. The mirror type display panel may comprise a substrate, a display member disposed on the substrate, the display member including a light emission region, a first transmission region, and a peripheral region surrounding the light emission region and the first transmission region, and a reflective member facing the substrate with respect to the display member, the reflective member including an opening region corresponding to the light emission region, a second transmission region corresponding to the first transmission region, and a reflective region surrounding the opening region and the second transmission region.
US10449900B2 Video synthesis system, video synthesis device, and video synthesis method
A video display system performs a video conversion process on a video of a camera mounted on a vehicle and displays a resulting video, and includes a plurality of cameras, a detecting unit that detects an object of interest around the vehicle based on information or the like acquired through the plurality of cameras, other sensors, or a network, a transforming/synthesizing unit that transforms and synthesizes the videos photographed by the plurality of cameras using a shape of a virtual projection plane, a virtual viewpoint, and a synthesis method which are decided according to position information of the object of interest detected by the detecting unit, and a display unit that displays the video that is transformed and synthesized by the transforming/synthesizing unit.
US10449898B2 Systems and methodologies for providing supplementary information based on alerts in a vehicle
Systems and methods are provided for providing supplementary alert information. The method includes monitoring, using processing circuitry, one or more systems in a vehicle to determine an alert mode when an alert is generated. The method further includes identifying, using the processing circuitry, supplementary alert information associated with the alert mode. The supplementary alert information includes an explanation of a trigger of the alert. The method further includes outputting the supplementary alert information to a user of the vehicle.
US10449894B2 Display device for displaying at least one symbol, switching device, and method for manufacturing a display device
One general aspect of the present disclosure includes a display device for a vehicle for displaying at least one symbol. The display device may include a translucent cover layer, a symbol layer having a translucent symbol panel for displaying a symbol, and an opaque surface encompassing the symbol panel. A gap may be disposed between the symbol panel and the cover layer. A waveguide assembly may be included and configured to conduct light onto a side of the symbol panel facing away from the cover layer.
US10449889B2 Systems and methods for receiving retail products
In some embodiments, apparatuses and methods are provided herein useful to receiving retail products. In some embodiments, there is provided a system for receiving retail products including: a temperature controlled storage container and comprising: one or more chambers having corresponding chamber temperatures that are each individually maintained and adjustable based on a particular temperature assigned by a separate electronic control device to each of the one or more chambers; one or more temperature sensors; one or more additional sensors; a locking system; and a storage container control circuit configured to: receive the particular temperature; maintain each one of the corresponding chamber temperatures; determine whether a first trigger signal is received; determine whether a second trigger signal is available; and provide the unlock signal; and the separate electronic control device configured to: provide the particular temperature; selectively assign each of the one or more retail products; and provide the second trigger signal.
US10449888B2 Trailer for transport of fracking sand
An assembly for a fracking sand trailer wherein a door can be positioned to allow a measured flow of sand to exit the assembly. The assembly can be attached to a hopper of a trailer and can stand the weight of heavy loads associated with sand. A trailer with the assembly is also described and utilizes specific construction techniques to lighten the weight of the trailer.
US10449887B2 Cargo carrying vehicle
Provided is a cargo carrying vehicle including; an elevating table 2 elevatable in the vertical direction; a plurality of rotating bodies 31 located on the elevating table 2 and configured to rotate so as to carry a cargo C in a conveyance direction X that is a direction toward a loading-unloading part of an aircraft; and a support 32 configured to support the plurality of rotating bodies 31, wherein the support 32 and the plurality of rotating bodies 31 constitute the conveying unit 3, and the conveying unit 3 is movable on the elevating table 2 in a position adjusting direction Y that is a direction intersecting the vertical direction and the conveyance direction.
US10449886B2 Container transfer system
A container transfer system is disclosed. The container transfer system includes a conveyance mechanism configured to support a container and move the container along a first axis, and a lift mechanism configured to raise and lower the conveyance mechanism.
US10449883B2 Apparatus and method for evaluating a seat by using body pressure distribution
The present disclosure relates to an apparatus and a method for evaluating a seat by using body pressure distribution. The apparatus includes: a body grid generator to generate body grids corresponding to body pressure data, which is measured while a driver is seated on a seat of a vehicle, based on the body pressure data and body information of the driver; a pressure analyzer to divide the body grids to a plurality of body grid areas based on body areas of the body pressure data and analyze the body pressure data included in the body grid areas; and a pressure evaluator to evaluate a body pressure for the seat based on the analyzed body pressure data of the body grid areas, and evaluate a hugging feeling of the driver for the seat based on the evaluated body pressure.
US10449881B2 Head rest
A headrest is provided including a movable unit that can be shifted to multiple positions in the front-rear direction in a normal mode. A headrest includes first and second headrest pillars, a stationary unit disposed between the first and second headrest pillars, a movable unit movable apart from or close to the stationary unit toward a front or rear direction, an X linkage connecting the stationary unit to the movable unit and including an inside linkage segment and an outside linkage segment rotatably connected each other at a central connecting intersection, and a front-rear locking mechanism including a lock receiver and a locking component engageable with the lock receiver, to lock or unlock the movable unit movable relative to the stationary unit toward the front or rear direction.
US10449880B2 Back frame structure of vehicle seat
A back frame structure of a vehicle seat including: first and second side frames; and an upper frame that connects the first and second side frames, wherein the first side frame has a constant cross section and the second side frame has a constant cross section, wherein an outline shape of the cross section of the first side frame and an outline shape of the cross section of the second side frame are in line symmetry with respect to a centerline of the back frame in a left and right direction, and wherein a geometrical moment of inertia of the cross section of the first side frame is larger than a geometrical moment of inertia of the cross section of the second side frame.
US10449879B2 Protective removable cover
A method and a protective removable cover are presented. The protective removable cover comprises a number of sheets of fabric joined together in a toroidal shape such that an interior of the toroidal shape and an exterior of the toroidal shape have a same surface. The number of sheets of fabric joined together in the toroidal shape is configured to roll over a monument such that the monument is substantially covered.
US10449870B2 Battery charge strategy using discharge cycle
A battery management system for a vehicle includes a controller programmed to charge a battery at a predetermined charge current. The controller activates an electrical load to discharge the battery for a predetermined time in response to a charge current of the battery becoming less than the predetermined charge current at a predetermined voltage limit. After discharging for the predetermined time, the controller resumes charging at the predetermined charge current. A current magnitude during the discharge and the predetermined time may be based on factors including the predetermined charge rate, a battery temperature, and a charge current magnitude during charging.
US10449869B2 Method for symmetrizing an energy storage system
In a method for balancing an energy storage system, a capacitance of capacitive storage modules of a series circuit of capacitive storage modules is determined. The capacitive storage modules are connected to a balancing device to allow control of a charge of each of the capacitive storage modules via a flow of current between the balancing device and the capacitive storage modules. For each of the capacitive storage modules a module charge is determined from a voltage of the capacitive storage module and a predefined balancing voltage. A reference charge is determined from the module charges of the capacitive storage modules, and a balancing charge is determined for each of the capacitive storage modules from the reference charge and the module charge of the capacitive storage module. The charge of the capacitive storage modules is controlled by exchanging the balancing charge between the capacitive storage module and the balancing device.
US10449865B2 System and method for powering on-road electric vehicles via wireless power transfer
A system for wireless power transfer of on-road vehicles is provided herein. The system includes a plurality of base stations; a power transmission line located beneath a surface of a road having a plurality of segments, each segment having at least one pair of coils and at least one capacitor electrically connected via a switch to the coils in the segment; and at least one vehicle having at least one power receiving segment having at least two coils, connected to at least one capacitor, wherein the at least one vehicle further includes a communication transmitter configured to transmit a power requesting signal, wherein the coils of the power transmitting segment are configured to receive the power requesting signal; and wherein each of the base stations is further configured to feed a plurality of the power transmitting segments with current at a resonance frequency, responsive to the power requesting signal.
US10449863B2 Regenerative brake control device
Provided is a regenerative coordination brake control device that reduces the frequency of switching regenerative braking between a restricted state, in which regenerative braking is prohibited or suppressed, and a restriction removed state, in which the restriction on regenerative braking is removed. A regenerative coordination brake control device 91 includes a regeneration restriction condition determiner 92, which outputs a regeneration restriction signal Si when determining that a restriction condition for prohibiting or suppressing regenerative braking is met, an acceleration operation detector 93, which outputs a regeneration restriction removal signal S2 when detecting an acceleration of the vehicle, and a regeneration restriction removal determiner 94, which determines whether a restriction on regenerative braking of the vehicle that is in the restricted state is to be continuously imposed or removed using the regeneration restriction removal signal S2 and the regeneration restriction signal S1.
US10449855B2 Driveline for off-highway vehicles provided with a dual function CVT
A driveline for vehicles provided with a dual function CVT is described herein. The driveline includes a dual function CVT that can be used both to power the ground engaging wheels of the vehicle and to power an accessory drive thereof.
US10449853B2 Compressed natural gas fueling system with integrated fill receptacle
A compressed natural gas fueling system includes a frame arrangement with at least one tank disposed therein and an inlet that can receive a compressed natural gas fueling nozzle to fill the at least one tank. The fueling system can be attached with and supported by frame rails behind a cabin of a vehicle such that the inlet is positioned above the frame rails.
US10449852B2 Fuel cap and seal assembly
The present invention provides a fuel cap including a body and a seal positioned on the body, the cap adapted for engaging a filler tube opening, and the seal positioned on the cap body such that the seal sealingly engages an inner diameter surface of a fuel filler neck to seal the cap to the fuel filler neck.
US10449850B2 Motor vehicle body comprising shutters with splitters and associated vehicle
Disclosed is a motor vehicle body, the body having a front surface, the front surface defining at least one air inlet, the body including at least one frame, the frame facing the air inlet, at least one shutter being mounted on the frame and extending across the frame, the shutter extending along a main axis along a transversal direction and defining at least one main guiding surface, the shutter being able to guide the airflow along a plane containing the main guiding surface. At least one splitter is located on the shutter, the splitter defining at least one secondary guiding surface, the secondary guiding surface forming a non-zero angle with the main guiding surface, the splitter being able to guide the airflow along a plane containing the secondary guiding surface.
US10449849B2 Mining machine and energy storage system for same
A mobile mining machine includes a plurality of traction elements, a plurality of motors, a power source in electrical communication with the plurality of motors, and an energy storage system in electrical communication with the plurality of motors and the power source. Each of the motors is coupled to an associated one of the plurality of traction elements. Each of the motors is driven by the associated traction element in a first mode, and drives the associated traction element in a second mode. The energy storage system includes a shaft, a rotor secured to the shaft, a stator extending around the rotor, and a flywheel coupled to the shaft for rotation therewith. In the first mode, rotation of the motors causes rotation of the flywheel to store kinetic energy. In the second mode, rotation of the rotor and the flywheel discharges kinetic energy to drive the motors.
US10449846B2 Transmission, control device, and vehicle
A transmission for outputting a rotational torque in accordance with a torque requirement. The transmission includes a generator, a motor and a control device. The generator includes a rotor configured to receive first rotational power from an engine, a stator including a stator core with a winding wound thereon, a magnetic circuit for the winding passing through the stator core, and a supply current adjustment device configured to adjust magnetic resistance of the magnetic circuit for the winding, to thereby change an inductance of the winding to adjust a current outputted by the generator. The motor is driven by the current outputted from the generator, to thereby output second rotational power. The control device controls the supply current adjustment device to change the inductance of the winding, in accordance with the torque requirement.
US10449843B2 Folding soft top with lift assist
A soft top assembly which includes lift assist and improved fabric management. The assembly includes front side rails pivotally connected to rear side rails. A plurality of fabric control bows with control linkages provide fabric control to the top material during pivoting of the front side rails. A first and second gas strut are attached to the rear side rails to assist lifting and controlled motion as the top is moved between a closed position and open sunroof position, as one strut is fully loaded and compressed while the other strut is fully loaded and open, for lift assist and dampening.
US10449840B2 Vehicle side portion structure
A vehicle side portion structure includes a vehicle body side portion in which a door opening portion allowing an occupant to enter or leave a vehicle is formed, the vehicle body side portion being configured to include a center pillar dividing the door opening portion into front and rear portions, a slide door disposed such that the door opening portion is openable and closable, the slide door in a closed state being disposed across the center pillar in a front-rear direction of the vehicle, and an elongated reinforcing member disposed inside the slide door with a longitudinal direction of the reinforcing member directed in the front-rear direction of the vehicle and intersecting with the center pillar in side view of the vehicle in the state where the slide door is closed.
US10449838B2 Shading device for a window pane of an automotive vehicle
Shading device for a window pane of an automotive vehicle including a flexible shading structure held on a winding shaft. The shaft is disposed in a vehicle-fixed accommodating region with a passage, through and across which passage the shading structure is displaceable between a rest position wound up on the winding shaft and a shading position covering the window pane. The passage is capable of being closed or exposed via a pivotably mounted closing part. A drive system is provided for displacing the shading structure between the rest position and the shading position, and control kinematics are provided, coupled to the drive system, for forced control of an opening or closing movement of the closing part. The control kinematics include a cable pull arrangement provided with a cable control pulley having at least one cable deflection track eccentric in relation to a rotational axis of the cable control pulley.
US10449835B2 Vane adjustment device and a vehicle air register assembly
A vane adjustment device for an air register having a front vane and a rear vane is disclosed. The vane adjustment device comprises a rear vane connector rotatably connected to the rear vane about a first axis, an intermediate connector rotatably connected to the rear vane connector about a second axis different with the first axis, and a front vane connector rotatably connected to the front vane, the front vane connector including a sliding portion slidably and rotatably connected to the intermediate connector.
US10449831B2 Air vent for mitigating hot air in vehicle
An air vent is mounted in a vehicle window frame. The air vent includes a one-piece body having an interior face and an exterior face. An air pathway extends between a first opening in the interior face to a second opening in the exterior face. An elongated window channel is also provided in the body for receiving the window over which the air vent is mounted.
US10449826B2 Device for controlling the temperature of a battery and of a vehicle interior, method for conditioning the temperature of a battery and of a vehicle interior with such a device for controlling temperature, and use of such a device for controlling temperature
A temperature control device for a battery and for a vehicle interior, having a first heat exchanger and having a second heat exchanger that are thermally coupled, the second heat exchanger being thermally coupled to the battery, and the first heat exchanger to a temperature control chamber that has a downstream segment that is thermally coupled to the vehicle interior and has a first upstream segment and a second upstream segment, the first upstream segment being thermally coupled to the vehicle interior and the second upstream segment to a surrounding environment of the vehicle, the first heat exchanger being capable of being thermally coupled alternately to the first upstream segment or to the second upstream segment.
US10449824B2 Air conditioning module
An air conditioning module, which can perform cooling and heating through a single module, which is capable of being compact-sized, which can prevent problems caused by condensate water because the condensate water can be easily discharged out, and which can control all of two doors for heating and cooling by a link member and an actuator.
US10449819B2 Damping convoluted air spring
A damping convoluted air spring for use in vehicle axle/suspension systems includes a top plate, a bottom plate, and a bellows. The bellows includes a first lobe, a second lobe, and a third lobe operatively connected to one another. The first lobe being in fluid communication with the second lobe. The second lobe being in fluid communication with said third lobe. The first lobe operatively mounted on the top plate. The third lobe operatively mounted on the bottom plate. The second lobe includes a fixed volume under pressure to provide damping to the air spring during operation of the vehicle.
US10449817B2 Slider wear pad
A slider suspension system for a heavy-duty vehicle includes a slider assembly with a main member that is movable relative to a primary frame of the heavy-duty vehicle in a first direction along the extent of the main member. The main member has a first portion and a second portion extending transverse to the first portion. A friction reducing slider wear pad is fixed to the main member and interposed between the main member and the primary frame. The friction reducing slider wear pad has a first segment fixed to the first portion of the main member. The friction reducing slider wear pad also has a second segment engaging at least a part of the second portion of the main member to inhibit movement of the friction reducing pad relative to the main member in a second direction transverse to the first direction.
US10449805B2 Non-pneumatic tire
There is provided a non-pneumatic tire (1), which includes an attachment body (11) that is attached to an axle, a ring-shaped body (13) that surrounds the attachment body (11) from an outside in a tire radial direction, a connection member (15) that displaceably connects the attachment body (11) and the ring-shaped body (13) to each other, and a cylindrical tread member (16) that is externally mounted on the ring-shaped body (13), in which the tread member (16) includes a base rubber portion (41) that is positioned at an inside in the tire radial direction, and a cap rubber portion (42) that is positioned at an outside of the base rubber portion (41) in the tire radial direction, and in which the rigidity of the base rubber portion (41) is lower than the rigidity of the cap rubber portion (42).
US10449804B1 Superelastic tire
A tire includes a plurality of SMA springs. Each SMA spring includes a first end portion, a second end portion, and an arching middle portion. Each SMA spring is interlaced with at least one other SMA spring thereby forming a laced toroidal structure extending about an entire circumference of the tire.
US10449803B2 Pneumatic tire
Provided is a pneumatic tire where a total width (SW) and an outer diameter (OD) satisfy the relationship SW/OD≤0.3; an inner diameter (ID) and an outer diameter (OD) satisfy the relationship ID/OD≥0.7; as viewed in a tire meridional cross section, an area (X1) (mm2) of a first region (R1) and a periphery length (Y1) (mm) of an inner peripheral surface of the first region (R1) have a ratio X1/Y1 of 12 or greater and 30 or less; and an area X2 (mm2) of a second region (R2) and a periphery length (Y2) (mm) of an inner peripheral surface of the second region (R2) have a ratio X2/Y2 of 10 or greater and 15 or less.
US10449801B2 Partial wheel cladding
A wheel assembly including a cover portion permanently attached to a wheel. The wheel includes a wheel central hub portion, a wheel outer peripheral rim portion, a plurality of wheel spoke portions extending between the wheel central hub portion and the wheel outer peripheral rim portion, and a plurality of wheel turbine openings disposed between adjacent ones of the plurality of wheel spoke portions. A cover portion is configured to overlie a portion of the wheel portion. The cover portion is configured to overlie one or more of the wheel central hub portion; the plurality of wheel spoke portions, and the plurality of turbine openings or the wheel outer periphery. An adhesive is disposed between an outboard surface of the wheel and the inboard surface of the cover portion to permanently secure the cover portion to the wheel portion. When the cover portion is secured to the wheel, substantial portions of the plurality of wheel spokes, the wheel central hub, or wheel outer periphery remain exposed.
US10449799B2 Attachment device and attachment method
In an attachment device, the atmospheric pressure of a lower space which is formed by a container and an attachment film and the atmospheric pressure of an upper space which is formed by a lid and the attachment film are varied to cause elastic deformation of the attachment film, so that a decorative sheet is attached to a cowl. Disposed inside the container are: a jig that puts the cowl in place; and a restriction plate which is disposed at a location close to the cowl so as to cause at least a part of the cowl to be exposed to the attachment film side, and which has a reception surface that restricts the elastic deformation of the attachment film. In addition, the reception surface is provided with a small through-hole that allows the air inside the lower space to flow therethrough.
US10449796B2 Method and system for processing printed products
A system for processing printed products includes a transfer station which is provided with an infeeding location for infeeding printed products to the transfer station from a delivery station. The transfer station further comprises a number of connecting locations and a removal location. To each of the connecting locations is connected a processing station. An output station is connected to the removal location. The transfer station is further provided with a transporting device for moving the printed products within the transfer device between the infeeding location, the various connecting locations and the removal location. The printed product infed to the transfer station at the infeeding location is transported in any sequence from the transfer station to one of the processing stations. After completion of the processing operation in a particular processing station, the printed product is moved back to the transfer station. The finished printed products are removed from the transfer station at the removal location.
US10449794B2 Method for forming image and protective layer and apparatus therefor
A method for forming an image and a protective layer on a transfer receiving material, by thermal transfer, including supplying a thermal transfer sheet between a thermal head of a thermal printer and a platen roller, wherein the thermal transfer sheet includes color material layers and a transferable protective layer arranged in a face serial manner, and wherein the thermal head includes heat generating portions arranged substantially in parallel with each other; thermally transferring the color material layers to form an image on the transfer receiving material; thermally transferring the transferable protective layer to form a protective layer on the transfer receiving material; and shifting the relative positions of the thermal head and the transfer receiving material with respect to each other, in a direction substantially in parallel with a main scanning direction, after transferring the color material layers at least once.
US10449792B2 Elastic bending mechanism for bi-directional adjustment of print head position
Mechanisms for adjusting the position of one or more print heads at an extremely fine resolution (e.g., less than 10 μm) are described herein. The adjustment mechanisms include a differential screw and an indexing wheel through which the differential screw extends. One threaded segment of the differential screw is connected to a threaded feature of a flexible body that is coupled to the print head(s), while another threaded segment of the differential screw is connected to a threaded feature of a rigid body that is coupled to a printer assembly. As the indexing wheel and differential screw rotate, the space between the flexible body and the rigid body changes based on the difference between the pitches of the threaded segments. The adjustment mechanisms described herein utilize the accurate, consistent motion of the flexible body upon experiencing pressure to effect predictable changes in the position of the print head(s).
US10449790B2 Printer and method for accurately recognizing positions of labels
A printer comprises a conveyance section configured to convey labels which are attached to a belt-like mount at predetermined gaps along a longitudinal direction of the mount; a printing section, configured to perform printing on the label; a detection section configured to detect light passing through the mount and the label and to perform output in which the increase and decrease in an amount of transmitted light are reflected; and a recognition section configured to recognize edges of the label by setting a position where the amount of transmitted light increases as a beginning of the gap and setting a position where the amount of transmitted light decreases as an end of the gap, and pretermit a trough between an increasing portion and a decreasing portion adjacent to each other when the increase and the decrease in the amount of transmitted light are repeated in a short conveyance interval.
US10449788B2 Cutting device and printer
A cutting device includes a fixed blade and a movable blade that slides with respect to the fixed blade during cutting, the movable blade having a first end that engages with the fixed blade at cutting start and a second end that engages with the fixed blade at cutting end, an urging member connected to the movable blade to urge the movable blade towards the fixed blade and a rotation of the movable blade in a first rotational direction, and a support for the movable blade having a shaft that rotates as the movable blade moves, the shaft having a center portion and first and second ends rotatably connected to the movable blade, wherein points of connection of the first and second ends are at locations that urge a rotation of the movable blade in a second rotational direction opposite the first rotational direction.
US10449787B2 Medium support unit, printing apparatus, heating apparatus, and printing method
A medium support unit that supports a medium to be printed on by a printing apparatus includes a support section and a frame section. The support section has a first support face and a second support face that are capable of supporting the medium. The frame section retains the support section. The frame section includes a first placement portion that is placed on a base of the printing apparatus when the first support face is set as a printing face on which the medium is printed, and a second placement portion that is placed on the base when the second support face is set as the printing face.
US10449786B2 Image forming system
An image forming system includes a transport section that includes a support surface supporting a sheet-like medium and transports the medium while supporting the medium on the support surface, a first pressure generating section that generates pressure used to suck the medium supported on the support surface, and an image forming section that forms an image on the medium transported by the transport section. First suction holes that communicate with the first pressure generating section, first protrusions, and sealed portions that are disposed at positions where end portions of the medium in the medium width direction are supported and restrict inflow of air to regions, in which the first suction holes are arranged, from the outside of the end portions of the medium in the medium width direction are arranged on the support surface in a medium support region where the medium can be supported.
US10449784B2 Printing device and printing method
To dry ink using a more appropriate method in a case of performing printing using an ink-jet printer of a line system and the like. A printing device that performs printing using an ink-jet system includes: a conveyance driving unit as a conveyance module that conveys a medium; ink-jet heads; and an ultraviolet ray irradiation unit as an energy irradiation module. A length of the ink-jet heads in a width direction of the medium is larger than a width of a region to be printed. Ink ejected from the ink-jet heads is ink that contains an energy ray absorber and a solvent, the ink being fixed to the medium by evaporating the solvent. The ultraviolet ray irradiation unit irradiates the ink adhering onto the medium with ultraviolet rays to volatilize and remove at least part of the solvent contained in the ink.
US10449781B2 Apparatus and method for thermal transfer printing
Methods, systems, and apparatus for thermal transfer printing include a band of material comprising a polyimide film, the band and a thickness of the band are selected based on heat transfer characteristics through the band; a print roller or platen configured and arranged to support a substrate; a printhead configured and arranged to thermally transfer ink from the band of material to the substrate; a combined heating and re-inking system comprising a heated ink roller comprising a textured outer surface, wherein a first portion of the heated ink roller contacts the band to cause ink on the band to re-melt, flow and replace at least some of the portion of the ink transferred to the substrate previously before arriving at the printhead again for a next print, and a second portion of the heated ink roller receives new ink; and a control system that matches the band and substrate speeds.
US10449780B2 Printer and printing method which varies area printable in one-pass printing
A printer includes a liquid discharge head and a processor. The liquid discharge head includes a plurality of nozzles. The plurality of nozzles include a line of first nozzles to discharge first liquid and a line of second nozzles to discharge second liquid. The processor is configured to change a print speed in a print mode in which a preceding image is formed with at least the first liquid and a subsequent image to be superimposed on the preceding image is formed with the second liquid, in accordance with an amount of liquid applied to a recording medium to form the preceding image.
US10449779B2 Image processing apparatus, printing apparatus, and program
An image processing apparatus, configured to generate print data to be outputted to a printing apparatus that prints an image by ejecting preprocessing liquid and ink onto a medium, includes a color conversion unit that converts image data representing the image into an amount of the preprocessing liquid, and a type and an amount of the ink for printing the image, and a print data generation unit that generates the print data on a basis of the amount of the preprocessing liquid and the type and amount of the ink. The color conversion unit converts the image data such that, when the amount of the preprocessing liquid for printing one pixel of a first image on the medium is defined as a first preprocessing liquid amount, and the amount of the preprocessing liquid for printing one pixel of a second image on the medium is defined as a second preprocessing liquid amount, the amount of the preprocessing liquid for printing a first layered pixel, in which the one pixel of the second image is superposed on the one pixel of the first image, becomes less than a total of the first preprocessing liquid amount and the second preprocessing liquid amount.
US10449778B2 Filter unit, liquid jetting module, and liquid jetting head
A filter unit includes: a liquid chamber forming member having a liquid inlet port, a liquid outlet port, and a liquid chamber communicating with the liquid inlet port and the liquid outlet port; and a filter disposed in the liquid chamber such that a surface direction of the filter lies along an up-down direction, the filter extending to an upper end of the liquid chamber to divide the liquid chamber into an upstream chamber communicating with the liquid inlet port and a downstream chamber communicating with the liquid outlet port. A discharge port joined to the liquid outlet port is disposed in an upper end portion of the downstream chamber at a central portion in a width direction orthogonal to the up-down direction, and the liquid chamber forming member has two first side wall surfaces sandwiching the discharge port in the width direction.
US10449776B2 Print head sensing chamber circulation
A print head has a fluid slot and a sensing chamber having a first port connected to the fluid slot and a second port. The sensing chamber contains an ink level sensor. A circulation passage extends from the fluid slot and is fluidly coupled to the second port. A fluid pump circulates fluid through the circulation passage.
US10449775B2 Liquid ejecting head and filter unit
A filter unit provided in a path for supplying liquid to a liquid ejector includes: an upstream compartment into which the liquid flows from an upstream channel; a downstream compartment from which the liquid flows into a downstream channel; and a filter that serves as a partition between the upstream compartment and the downstream compartment. The upstream compartment overlaps the downstream compartment in a first direction intersecting the vertical direction. The downstream compartment has at least one first downstream opening and at least one second downstream opening in communication with the downstream channel. The second downstream opening is disposed below the first downstream opening in the vertical direction.
US10449774B2 System for advanced protection of consumable or detachable elements
A method of authenticating a consumable or detachable element of a continuous inkjet printer comprising: the controller of the printer generating a 1st item of random information that is dispatched to an authentication circuit of the element; encrypting the 1st item of information by the authentication circuit using a 1st encryption algorithm and a 1st secret key to form a 1st item of encrypted random information; dispatching the 1st item of information to the controller; encrypting the 1st item of information by the controller using a 2nd encryption algorithm and a 2nd secret key to form a 2nd item of encrypted random information; comparing the 1st item of encrypted random information with the 2nd encrypted item of random information to authenticate the consumable element; and if the consumable element is authenticated, dispatching at least one part of a 3rd key, termed the shared key, by the element to the printer.
US10449772B2 Cartridge and liquid ejection system
A cartridge includes: a case; an accommodation part inside of the case; a liquid leading-out port; a cartridge side electrical connection part; and a cartridge side fixation structure. Engagement of the device side fixation structure and the cartridge side fixation structure restricts moving the case in a state of being imparted with the force directing to −Z direction. The cartridge side fixation structure and the cartridge side electrical connection part overlap with each other at least in a part when the cartridge is viewed in Z directions. A width of the cartridge in the Z direction is smaller than a width in Y direction and a width in the X directions.
US10449771B2 Liquid cartridge capable of improving visibility to liquid stored in liquid storage chamber
A liquid cartridge includes: a cartridge casing having a liquid storage chamber defined by a front wall, a rear wall, a bottom wall, a first side wall, and a second side wall; and a liquid supply portion; a top wall; and an accessed member. The liquid supply portion has a liquid supply hole extending from the liquid storage chamber to the outside in a frontward direction. The front, rear, first side, and second side walls are formed of a material permitting the liquid stored in the liquid storage chamber to be visually recognized from the outside. Each of the front, rear, first side, and second side walls includes a portion forming an outer wall of the cartridge casing exposed to the outside of the cartridge casing. The accessed member is disposed upward relative to the liquid storage chamber and accessed from the outside.
US10449769B2 Hybrid printhead maintenance system for wiping and priming
A maintenance system for maintaining an elongate inkjet printhead. The maintenance system includes: a carriage movable longitudinally along the printhead, the carriage including a maintenance member having a primary suction nozzle facing inkjet nozzles of the printhead and a wiper adjacent the primary suction nozzle; a traversing mechanism for traversing the carriage longitudinally along the printhead; and an engagement mechanism for urging the wiper and the printhead into engagement with each other. During use, the wiper contacts a non-printing part of the printhead and the primary suction nozzle is spaced apart from the printhead.
US10449756B2 Three dimensional printing apparatus
A three dimensional printing apparatus is provided, and the three dimensional printing apparatus includes a modeling portion, a powder supplying portion, a powder spreading mechanism, a printing mechanism and a controller. The powder supplying portion is filled with a powder forming material. The powder spreading mechanism is disposed on a first side of the modeling portion, and is configured to transfer the powder forming material from the powder supplying portion to spread the powder forming material on the supporting platform. The printing mechanism is disposed on a second side of the modeling portion which is opposite to the first side, and is configured to eject the glue material. The controller operates in a fast mode according to a fast mode instruction, so as to control the printing mechanism to eject the glue material onto the powder forming material while moving along a first direction with the powder spreading mechanism.
US10449751B2 Method for manufacturing high strength galvanized steel sheet
A method for manufacturing a high strength galvanized steel sheet which has a zinc coating layer with an amount of deposition of coating of 20 to 120 g/m2 per one surface on the surface of a base steel sheet having a chemical composition comprising C: 0.03% to 0.35%, Si: 0.01% to 0.50%, Mn: 3.6% to 8.0%, Al: 0.001% to 1.000%, P≤0.10%, S≤0.010%, and the balance comprising Fe and incidental impurities, on a percent by mass basis, is provided. In annealing and galvanization treatment of the base steel sheet in a continuous galvanizing line, the maximum steel sheet temperature in an annealing furnace is 600° C. or higher and 750° C. or lower, the steel sheet transit time in a temperature region of the steel sheet temperature of 600° C. or higher and 750° C. or lower is specified to be 30 seconds or more and 10 minutes or less, and the dew point in an atmosphere is specified to be −10° C. or higher.
US10449748B2 Decorative board
A decorative board 5 includes: a prepreg 2 that includes a binder component including: at least one thermoplastic resin selected from a group consisting of acrylic resin having a glass-transition temperature Tg exceeding 0° C., vinyl chloride resin having a glass-transition temperature Tg exceeding 0° C., acrylic urethane, and aqueous polyurethane resin, and a thermosetting resin, a mixing ratio of the at least one thermoplastic resin to the thermosetting resin being 1:0-0.5 in solid content ratio, and an endothermic metal hydroxide; and a thermosetting resin impregnated decorative paper 1, wherein the prepreg and the thermosetting resin impregnated decorative paper are stacked and integrated.
US10449746B2 Web processing system with multiple folding arrangements fed by a single web handling arrangement
A web processing system is provided. The web processing system supplies a processed continuous web of material to a cutting arrangement. The cutting arrangement forms sheets from the continuous web of material. The sheets are then supplied to multiple folding arrangements such that a single web of material is used to supply sheets to multiple folding arrangements.
US10449741B2 Rigid core mold removal device and tire manufacturing method
A method for manufacturing a tire T comprises a step for forming a green tire on the outside of a rigid core mold 2, a step for vulcanization-molding and obtaining a tire-accompanying rigid core mold G, a step for setting, at an assembly station P3, a core 5 taken out from the tire-accompanied rigid core mold G, and a removal and assembly step for removing one core segment 3 from the tire T by moving in inwardly in the tire radial direction from the tire-accompanying rigid core mold G and mounting it on the core 5 set at the assembly station. The removal and assembly step is performed for every core segment in the tire, whereby a rigid core mold 2 is assembled at the assembly station P3, while removing the rigid core mold 2 from the tire T.
US10449733B2 Methods of manufacturing single piece multi-spar boxes of composite material in a closed mould
Methods of making single piece multi-spar boxes made of composite material for aircraft are provided. Such methods include providing outer spars of the boxes which are made with a C-shaped cross-section such that the spars, during curing, are molded on the inside onto rigid, outer, lateral forming tools. As a result it is possible to obtain very precise outer profiles and positions of the spars.
US10449729B1 3D printed fiber optics
A 3D printing system includes a 3D printer configured to receive as input a coated or un-coated optical fiber, to coat the optical fiber in the case of an input un-coated optical fiber, to treat an outer coating of the coated optical fiber, and to precisely output the coated optical fiber onto a specific location on a substrate such that the coated optical fiber is securely attached to the substrate via the treated outer coating. The 3D printer has a nozzle head that includes treating element for treating, such as heating or curing, the outer coating of the coated optical fiber. The 3D printer also includes a movement mechanism, such as an XYZ gantry, coupled to the nozzle head such that the nozzle head can be precisely moved relative to the substrate for well controlled placement of the treated coated optical fiber on the substrate.
US10449728B2 Forming assembly and method for forming a plurality of sealed packs for pourable food products starting from a tube of packaging material
There is described a forming assembly (10a, 10b) for forming a plurality of sealed packs (3) starting from a tube (2) of packaging material, comprising: a track (13a, 13b); a first element (15a, 15b), which is cyclically movable along the track (13a, 13b) and comprises, in turn, one of a sealing element (22b) or a counter-sealing element (22a) adapted to seal the pack (3); and a second element (14a, 14b), which is cyclically movable along the track (13a, 13b) and comprises, in turn, a first half-shell (21a, 21b; 21a′, 21b′) adapted, in use, contact the tube (2) so as to bound at least part of a respective pack (3) and control the shape of the pack (3) during the formation thereof; the first element (15a, 15b) and the second element (14a, 14b) are self-movable along the track (13a, 13b) independently of one another.
US10449721B2 Systems and method for monitoring three-dimensional printing
This invention provides systems and method for monitoring three-dimensional printing of printing material. A system comprises two coplanar and electrically conductive electrodes and a substrate, which provides a printing surface. The proximate edges of the electrodes, which are on the surface, are separate by a distance ranging from 5 mm to 300 mm. Each electrode is smaller in area than the substrate. The system also comprises a plurality of layers, which are formed layer-by-layer by the printing, and are derived from the printing material. The electrodes are electrically oppositely charged, as enabled by an alternating electric current between the two electrodes. The current partly flows in the layers. The two electrodes exhibit between them a capacitance ranging from 0.1 pF to 10 nF.
US10449720B2 Solid object shaping apparatus, control method for solid object shaping apparatus, and control program for solid object shaping apparatus
A solid object shaping apparatus includes a head unit, and a curing unit, in which a model indicating a shape and a color of a solid object to be shaped is approximated with a set of voxels each having a predetermined rectangular parallelepiped shape, a unit shaping body formed by a single dot or a plurality of dots is formed in the voxel, and the solid object is shaped by using the plurality of unit shaping bodies, and in which the plurality of unit shaping bodies constituting the solid object include a first and second unit shaping body. In the second unit shaping body, two or more faces forming a surface of the second unit shaping body correspond to a surface of the solid object, and a proportion of an inner portion of the model occupying the second unit shaping body is equal to or less than a reference value.
US10449718B1 Powder-layer three-dimensional printer with smoothing device
A powder layer smoothing devices adapted for use with powder-layer three-dimensional printers are described. The smoothing devices include a counter rotating roller having a complex powder engaging face that may include a series or plurality of flutes or may include knurling extending along at least a portion of the roller along the rotational axis. The smoothing device may also include a vertically adjustable finishing roller to follow the counter rotating roller across the build box of the powder-layer three-dimensional printer.
US10449715B2 Stereolithography color 3D printing method
A stereolithography color 3D printing method applied to a stereolithography color 3D printer (1) having a light module (11), a coloring module (12) and a curing platform (17) is provided. The method is to lower the curing platform (17) a default height (h), operate the light module (11) to irradiate stereolithography materials (180) on the curing platform (17) for curing the stereolithography materials (180) and manufacturing one layer of slice physical model (182, 30, 31) according to one layer of object print data, operate the coloring module (12) to color the slice physical model (182, 30, 31), and perform above-mentioned operations repeatedly until a color 3D physical model has been manufactured. Therefore, better printing performance can be achieved and colored 3D physical model with high definition can be manufactured by combining the stereolithography technology with the auto-coloring technology.
US10449714B2 Process for producing an object from a precursor and use of a free-radically crosslinkable resin in an additive manufacturing process
A process for producing an object from a precursor comprises the steps of: depositing a free-radically crosslinked resin atop a carrier to obtain a ply of a construction material joined to the carrier which corresponds to a first selected cross section of the precursor; depositing a free-radically crosslinked resin atop a previously applied ply of the construction material to obtain a further ply of the construction material which corresponds to a further selected cross section of the precursor and which is joined to the previously applied ply; repeating step II) until the precursor is formed; wherein the depositing of a free-radically crosslinked resin at least in step II) is effected by exposure and/or irradiation of a selected region of a free-radically crosslinkable resin corresponding to the respectively selected cross section of the object and wherein the free-radically crosslinkable resin has a viscosity (23° C., DIN EN ISO 2884-1) of ≥5 mPas to ≤100000 mPas. In the process the free-radically crosslinkable resin comprises a curable component in which NCO groups and olefinic C═C double bonds are present, wherein in the curable component the molar ratio of NCO groups to olefinic C═C double bonds is in a range from ≥1:5 to ≤5:1.
US10449712B2 Three-dimensional printing system and equipment assembly
A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
US10449708B2 Method and apparatus for sterilizing bottle
A method of sterilizing a bottle includes steps of: sterilizing bacteria adhering to a preform (1) made of resin by gasifying a sterilizer, discharging a sterilized gas (G) from a nozzle (6) toward a preform, now traveling, so as to adhere to the preform (1); activating the sterilizer adhering to the preform by blasting hot air (P) to the preform; sterilizing the bacteria adhering to the preform, and removing the sterilizer adhering to the preform (1); heating the preform to a temperature suitable for blow-molding treatment; and blow-molding the preform within a mold (4) to mold the preform into a bottle (2), wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.
US10449707B2 Method of injection molding using one or more strain gauges as a virtual sensor
A injection molding method involves measuring, using at least one strain gauge sensor, a change in strain in a mold side of a mold cavity, approximating a pressure within the mold cavity based on the change in strain, comparing the approximated pressure to a pre-set trigger point, and if the approximated pressure equals or exceeds the pre-set trigger point, activating a virtual cavity sensor having an optimal pre-defined pressure-time curve, wherein upon activation, the virtual cavity sensor tracks approximated pressures calculated from the change in strain measurements measured by the at least one strain gauge sensor over time and compares the results of the approximated pressure tracking to the optimal pre-defined pressure-time curve.
US10449706B2 Hot runner nozzle with a gate pressure equalizer
A method and apparatus for equalizing gate pressure of a hot runner nozzle are disclosed. The nozzle includes a nozzle housing defining a primary melt channel, a first nozzle tip having a first secondary melt channel in fluid communication with the primary melt channel, a second nozzle tip having a second secondary melt channel in fluid communication with the primary melt channel, and a valve disposed in the primary melt channel for selectively opening and closing a downstream end of the primary melt channel to control a flow of melt to the first and second secondary melt channels. In some embodiments, the valve is configured to selectively open when a pressure of the melt reaches a threshold peak pressure. In some embodiments, the valve includes a valve stem that cooperates with the primary melt channel to block a flow of melt therefrom until the threshold peak pressure is established.
US10449702B2 Laterally-coalesced foam slab
Laterally-coalesced foam slabs and methods and apparatus, including foaming dies, for making and using such foam slabs.
US10449686B2 Cutting line positioning apparatus and method that determine and place cutting line at optimal location on sheet to be cut
A candidate point selection processor selects, as candidate points, vertices on an outline. A search point selection processor selects, from the candidate points, a reference search point to be used to search for a point that serves as a cutting line endpoint. A reference line setting processor sets a reference line connecting a reference point with the search point. A candidate line setting processor sets candidate lines connecting the search point with the candidate points other than the search point. A candidate line selection processor selects, as a selected candidate line, the candidate line located only within a non-effective region. An angle calculation processor calculates an angle between the reference line and the selected candidate line. A cutting line setting processor sets a cutting line connecting the search point with the candidate point of the selected candidate line defining an angle with the reference line that is the smallest angle calculated.
US10449685B2 Food processor with adjustable blade assembly
A food processor includes a bowl with a removable lid. Food items are advanced into the bowl through a feed tube formed in the lid where they are cut by a blade assembly. A rotating disk is adjustable relative to the blade assembly to vary the thickness of the food items cut by the blade assembly.
US10449684B2 Synthetic turf seam integration template system and methods of use
A synthetic turf seam integration template system and method is provided that includes a template having a planar base with a positioner. The planar base is configured with a longitudinal cutting edge with a predetermined curvature and an opposing longitudinal non-cutting edge. The positioner, which aids in moving the template, is attached perpendicularly. Variations of the predetermined curvature patterns are disclosed. An optional connector allows connection of two templates to create a longer template for usage on longer seams. Also disclosed are methods of using the seam integration tool in creating an undetectable seam in synthetic turf.
US10449682B2 Coupling mechanism for a drive train of a hair cutting appliance
A self-aligning coupling linkage for a drive train, of a hair cutting appliance having a driving shaft and a non-aligning output shaft, includes a joint section having first and second connector portions that are configured to engage one another for torque transmission. The first second connector portions define a male connector having an external polygonal profile, viewed in a cross-sectional plane perpendicular to a longitudinal axis, and a female connector having an internal engagement profile. The male and female connectors are arranged in a self-aligning fashion for angular offset compensation, where wherein at least one of the male and female connectors is provided with at least one circumferentially arranged deflectable compensation element configured to urge the male and female connectors towards a centered alignment.
US10449673B2 Enhanced configuration and control of robots
Concepts and technologies are described herein for providing enhanced configuration and control of robots. Configurations disclosed herein augment a mobile computing device, such as a robot, with resources for understanding and navigation of an environment surrounding the computing device. The resources can include sensors of a separate computing device, which may be in the form of a head-mounted display. Data produced by the resources can be used to generate instructions for the mobile computing device. The sensors of the separate computing device can also detect a change in an environment or a conflict in the actions of the mobile computing device, and dynamically modify the generated instructions. By the use of the techniques disclosed herein, a simple, low-cost robot can understand and navigate through a complex environment and appropriately interact with obstacles and other objects.
US10449672B2 Wearable electromyography sensor array using conductive cloth electrodes for human-robot interactions
A sleeve worn on an arm allows detection of gestures by an array of sensors. Electromyography, inertial, and magnetic field sensors provide data that is processed to categorize gestures and translate the gestures into commands for robotic systems. Machine learning allows training of gestures to increase accuracy of detection for different users.
US10449671B2 Methods and systems for providing robotic operation constraints for remote controllable robots
A method of constraining operation of a robot includes receiving, using network interface hardware of a robot, one or more robotic control instructions from a user, where the robotic control instructions instruct the robot to perform a robotic movement, determining whether the user providing the one or more robotic control instructions to the robot is a primary user or a secondary user, and comparing the robotic movement instructed by the one or more robotic control instructions with one or more robotic operation constraints. The method further includes determining whether the robotic movement instructed by the one or more robotic control instructions conflicts with the one or more robotic operation constraints and constraining operation of the robot when the user is the secondary user and the robotic movement instructed by the one or more robotic control instructions conflicts with the one or more robotic operation constraints.
US10449659B2 Abrasive article having a core including a composite material
An abrasive article including a bonded abrasive body coupled to a core, the core includes a composite material including an organic material and a metallic material, and the composite material includes at least a first filler that can include nitrides, carbides, borides, oxides, silicates, or a combination thereof.
US10449657B2 Tank assembly and method of use
A tank assembly. Said tank assembly comprises a one or more blister assemblies, a shell assembly, a one or more air inlet hoses, a one or more spray equipment and a slurry mixture. Said one or more blister assemblies comprises a first blister assembly and a second blister assembly. Said one or more blister assemblies comprise a one or more draw tubes, a one or more cone flanges, a one or more head assemblies, a one or more shells, a one or more cone assemblies, an air line assembly, a one or more snorkel assemblies, and a separation distance. Said one or more draw tubes comprise a first draw tube and a second draw tube. Said separation distance between said one or more draw tubes is configured to allow said one or more spray equipment to rotate freely on said one or more draw tubes without interfering with one another.
US10449652B2 Ophthalmic lens edging process by calculation
Described are systems and methods for controlling an ophthalmic lens edging machine are disclosed. The ophthalmic lens edging machine uses an edger code to select a macro or speed for a requested lens edging job. A system for creating and using the edger code may include a Lab Management System (LMS), a lens calculation system, and a lens edging machine. An edger code may be generated using lens data received from a lens management system and edging machine information identifying lens edging machines. The edger code comprises a plurality of characters. Each character is associated with a different feature of a requested edging job. The features of the requested edging job may include, for example, one or more of: a material type, a lens thickness, an edge type, a frame type, a lens coating, a lens shape, a lens ratio, a lens treatment, and an edging machine block type.
US10449649B2 Retainer ring structure for chemical-mechanical polishing apparatus and method for manufacturing the same
The present invention relates to a retainer ring structure for a CMP apparatus and a method for manufacturing the same. The retainer ring structure may include screws for fixing the retainer ring structure mounted on a polishing head during a CMP process, the screw being made of a high-strength metallic material, and the method for manufacturing the retainer ring structure may be simplified. Thus, a coupling force with the polishing head may be increased to reduce a defect rate, and the process may be simplified to reduce an operation time and a manufacturing cost, thereby increasing merchantability.
US10449648B2 Transferring rotation torque through isolator for table saw
An output member is configured to transfer rotation and torque from a motor of a power tool to a working element of the power tool. The working element is configured to contact a workpiece. The output member includes a hub, an outer shell, and an isolator. The hub is configured to be driven rotationally about an axis of rotation by the motor of the power tool. The outer shell is configured to be coupled to the working element of the power tool. The isolator is interposed between the hub and the outer shell and is configured to electrically isolate the hub from the outer shell.
US10449643B2 Snap ring insertion apparatus
A snap ring insertion apparatus is provided and configured to install a snap ring on a structural member. The snap ring insertion apparatus includes a pneumatic cylinder assembly configured to receive compressed gas and transfer a power of an expansion of the compressed gas to linear movement of a rod. An insertion assembly is coupled to the rod. The insertion assembly has an expander pin and a plurality of fingers pivotably coupled to a finger support member. The finger support member is coupled to the rod in a manner such that linear movement of the rod provides linear movement of the expander pin and pivoting movement of the fingers. Pivoting movement of the fingers results in engagement of the fingers with a snap ring and further pivoting of the fingers results in an expansion of the snap ring in a radial direction.
US10449642B2 Nut runner system
Nut runner system which includes holder table having tightening point at one end and coupling part at other end, and configured to hold plurality of bits, and nut runner main body including carrier coupled to wrist part of robotic arm, spindle supported by carrier, and bit changer coupled to spindle and which one of plurality of bits is attached. Coupling part of each of plurality of bits has an engaging hole coaxial with tightening point, and annular protrusion that continues in circumferential directions is formed in inner circumferential surface of engaging hole. Bit changer includes actuator, actuator made of engaging shaft to be inserted into engaging hole and operating pieces formed in engaging shaft, operating pieces moving between engaging position wherein operating pieces protrude radially outward from inner circumferential edge of annular protrusion and retracted position wherein operating pieces are retracted radially inward from inner circumferential edge of annular protrusion.
US10449641B2 System for manufacturing assembly board and method for installing undersupporting device of the system
A system for manufacturing an assembly board includes an undersupporting device, a carrier configured to hold the undersupporting device, a transporter, an undersupporting-device installer attachable to and detachable from the undersupporting device, a board processor, and a magnet provided on a lower surface of the undersupporting device. The transporter transports the undersupporting device to a working position by transporting the carrier to the working position while the carrier holds the undersupporting device on the lower surface of the carrier. The transported undersupporting device is fixed to the undersupporting-device installer by a magnetic force of the magnet at the working position. The transporter transports the board to the working position. The undersupporting device supports the lower surface of the board when the board is transported to the working position. The board processor performs a predetermined processing to an upper surface of the board.
US10449634B2 Laser build-up method
A laser build-up method according to an embodiment includes the processes of: forming an annular counter sunk groove 15 in an edge of an opening of a port on a side of a combustion chamber; and irradiating a laser beam 30 while a metallic powder 26 is being supplied to the counter sunk groove 15 and successively forming a cladding layer 16 for a valve seat, in which: the cladding layer 16 is formed while a seal gas 24 is being sprayed onto a melt pool 31, the cladding layer 16 includes a starting end part 17a, a part formed just after the starting end part is formed 18a, an intermediate part 18b, a part formed just before a terminating end part is formed 18c, and a terminating end part 17b, which are formed in this order.
US10449630B2 Invisible laser system and optical path visualization method thereof
An invisible laser system and an optical path visualization method thereof are disclosed. The invisible laser system comprises an invisible laser light generator for generating invisible laser light; a visible light generator for generating visible light; and an optical path visualization component arranged in optical paths of the invisible and visible light, and comprising a first and second incident end and a first outgoing end. The invisible laser light is incident on the first incident end, and the visible light is incident on the second incident end. All of the invisible laser light and at least part of the visible light are emitted in parallel with each other at the first outgoing end. All of the invisible laser light is present in a direction parallel with the optical path of the visible light, and no invisible laser light is present in other directions, so radiation risks are eliminated.
US10449627B2 Wedge bonding tools, wedge bonding systems, and related methods
A wedge bonding tool including a body portion including a tip portion is provided. The tip portion includes a working surface configured to contact a wire material during formation of a wedge bond. A plurality of notches are defined by one or more surfaces of the body portion.
US10449625B2 Production method for magnetic inductor
A magnetic inductor for heating parts by means of induction having a geometry with a density greater than or equal to 99.9% (absence of pores), produced by a plurality of welded layers formed by metal dust particles of a conductive, non-magnetic material (such as, inter alia, copper, tin, aluminum, gold, or silver), preferably copper or a copper-based alloy, having a spherical shape and a grain size between 40 and 100 μm, and in a single-piece part including electrical and mechanical connections. Also, a method for producing the magnetic inductor with EBM technology (electron beam melting/production technology based on electron beam fusion), using a system comprising an electron gun, a vacuum chamber, a working chamber and a manipulation system.
US10449619B2 System for processing a workpiece
A system (40) for processing a workpiece includes a support surface (88) for supporting a workpiece (44). The system (40) includes a processing tool (92) movable with respect to a processing path. The system (40) includes a sensor carriage (408) movable along a scan axis and having a light source (476, 515, 550, 586) located to emit a light beam at an angle to the scan axis onto a target surface of a workpiece (44), and a camera (484, 522, 558, 594) configured to record location data of the light beam on a target surface of a workpiece (44) as the sensor carriage (408) moves along the scan axis. The system (40) includes a control system for generating a three-dimensional point representation of a workpiece surface from the light beam location data, to control movement of the processing tool (92) based on the three-dimensional point representation of a workpiece (44).
US10449612B2 Methods of milling a piece of raw steel stock into a machine-ready piece of steel
A method of milling a piece of raw steel stock comprising: presenting a piece of raw steel stock having a first surface and a second surface having a perimeter; presenting a magnetic chuck with a top surface configured to support the piece of raw steel stock for milling with magnetic capabilities; arranging a minimum of four solid pole extensions on the top surface to support the second surface of the piece of raw steel stock for milling of the first surface thereof such that the solid pole extensions will be relatively evenly distributed beneath the perimeter of the second surface; arranging multiple mobile pole extensions on the top surface to further support the second surface; placing the second surface onto the multiple mobile pole extensions and the solid pole extensions; activating the magnetic capabilities of the magnetic chuck; and milling the first surface to a desired flatness.
US10449610B2 Method for machining flat surfaces of a workpiece
The invention relates to a method for machining flat surfaces (30) of a workpiece (32) using a tool (10), in particular a milling tool, which is moved in a collision-free and laterally inclined manner (α) relative to a flat surface (30) such that a contact point (34) is guided on the flat surface (30). The flat surface (30) is machined using a tool (10) with a cutting contour (18), which has a conically convex design, on one flank (16) of the tool (10) at a pivot angle (ß) parallel to the flat surface (30) in order to prevent a one-sided collision completely by the tool (10) and at at least two different pivot angles (ß, ß′) parallel to the flat surface (30) in order to prevent a two-sided collision by the tool (10), wherein the flat surface (30) is separated into at least two machining segments (44, 44′, 44″), each of which is assigned an individual pivot angle (ß, ß′) of the tool (10) in order to prevent a two-sided collision.
US10449608B2 Toolholder assembly with lock rod
A toolholder assembly includes a toolholder having a rearwardly facing toolholder shank, a base member having a bore configured for receiving the toolholder shank, a canister configured for receipt in the bore of the base member, a lock rod with an axial forward and an axial rearward end, wherein the axial forward end of the lock rod includes a compression void such as a compression aperture or compression slot formed therethrough, and at least one locking member in communication with the axial forward end of the lock rod.
US10449602B2 Magnesium alloy cast-rolling unit
A magnesium alloy cast-rolling unit, including: a main body; a fluid supplier; an electric pushrod; a linkage mechanism; a horizontal platform; a screw; dovetail guide rails; and a bottom plate. The main body includes a base, a spring cylinder, a hydraulic adjustment cylinder, a connection portion, and a cast-rolling unit body. The connection portion includes an arc-shaped rail. The spring cylinder includes an actuation element. The actuation element includes a piston rod and a pressure strip. The piston rod includes an external thread at one end; and the pressure strip includes an internal thread corresponding to the external thread. The fluid supplier includes a head box, a corrugated pipe, a compression spring assembly including a gland cover, a connection pipe including a convex pipe joint and a concave pipe joint, a flat plate including a groove, a smelting furnace, and a horizontal operation platform.
US10449598B2 Gearwheel having an axial undercut
A method for producing a gearwheel having an axis of rotation and a tooth system. The teeth have an axial undercut on the tooth flank sides thereof. A blank is provided having a tooth system, wherein the teeth of the tooth system are provided so as to be tilted relative to the axis of rotation such that a forming tool can advance substantially fully into the tooth flank sides of the teeth through an axial linear motion along the axis of rotation. A preliminary form of the at least one axial undercut can be provided on the tooth flank sides. A first axial forming operation is performed in the form of a first axial forging blow via which a preliminary form of the at least one axial undercut is introduced on the tooth flank sides or an already existing preliminary form of an axial undercut is sized for accuracy.
US10449597B2 Method for the surface treatment of a workpiece
A method for the surface treatment of a metal workpiece, in particular of a coated metal workpiece, for hot forming includes partially or completely heating the workpieces to a temperature of at least Ac1, cleaning at least one surface of the heated workpiece with at least one pressurized air jet, forming the heated and cleaned workpiece, and cooling down the formed workpiece.
US10449592B2 Method for removing a workpiece part and machine tool
A method for removal of a workpiece part from a residual workpiece of a sheet-like workpiece includes detecting an interlocking of the workpiece part with the residual workpiece. The workpiece is fixed for machining by a holding device and movable in an X-Y plane of the workpiece. The workpiece part is formed by cutting machining on the workpiece resting on a workpiece support. Before or after the cutting, a gripper device is positioned in a removal position relative to the workpiece part, and the gripper device is activated and the workpiece part is gripped in its position resting on the workpiece support. The method includes initiating at least one release strategy for automatic workpiece removal. At least one travelling movement with at least one travel path of at least one of the holding device and the gripper device is activated with at least one movement component in the X-Y plane.
US10449591B2 Sheet roll forming method, and running cutter and round bender applied thereto
A sheet roll forming method includes an uncoiling step for uncoiling a coil by an uncoiler provided at a start of a process line, a straightening step for straightening the coil from the uncoiler to be a flat panel, a piercing step for forming holes for various purposes in the panel fed from the straightening step by a piercing press, a sheet roll forming step for cutting the panel to be a sheet with a predetermined dimension by a running cutter and for successively bending the cut sheet to be a shaped beam by a multi-stage roll forming unit, and a bending step for curvature forming the shaped beam to be a shaped product by a round bender.
US10449589B2 Method and device for forming grooves in pipe elements
A method of forming circumferential grooves in pipe elements using opposed rollers to cold work the pipe elements determines the diameter of the groove while the pipe element is rotated between the rollers. A device for executing the method uses the instantaneous determinations of the groove depth in a feed-back loop to control the operation of the device and halt groove formation when the groove depth is within a specified tolerance.
US10449579B2 Devices and techniques relating to landfill gas extraction
A control system for controlling extraction of landfill gas, the system comprising: at least one sensor; at least one flow control mechanism; and at least one processor configured to perform: obtaining a first measure of energy content in a first portion of landfill gas; controlling the at least one flow control mechanism to increase a flow rate of landfill gas; after the controlling, obtaining a second measure of energy content in a second portion of landfill gas; when it is determined that the second measure of energy content is greater than the first measure of energy content, controlling the at least one flow control mechanism to increase the flow rate of landfill gas; and when it is determined that the second measure of energy content is less than the first measure of energy content, controlling the at least one flow control mechanism to decrease the flow rate of landfill gas.
US10449576B1 Weighted dock maintenance tool
A scraping tool having a thick, durable scraping blade attached to a weighted main body is particularly useful in scraping encrusted marine growth from seawalls, dock and pier pilings, and bridge structures is disclosed. A scraping blade formed of 316 Stainless Steel having a thickness of approximately 3/16″, with a front end that is preferably angled approximately 15-degrees from the longitudinal axis of the tool arranges the blade for maximum effectiveness. The blade has teeth with each tooth defining a beveled upper tip surface to aid in piercing encrusted barnacle growth. The blade is attached to a weighted main body which further includes an axially projecting adaptor for connection to an extension pole. The weighted main body is partially filled with lead shot for enhancing impact forces.
US10449575B2 Integrated cleaning and disinfection device, system and method
A single piece device enables medical clinicians to clean and disinfect both an injection port (needleless I.V. connector) and a vascular access catheter hub. The device has a body with a first end having a blind hole with a wall adapted to be engageable with the threads on the housing of an IV connector and a bottom surface adapted to engage the top surface of the IV connector. The device body has a second end defining a male-luer slip extending out of a recess. The male-luer slip is adapted to extend into a standard vascular access catheter hub such that it engages the inner walls of the catheter hub, and the recess is adapted to receive and be engageable with the outside thread element of the catheter hub.
US10449573B2 Sorting apparatus
A sorting apparatus is described and which includes a selectively heated avalanche photodiode (APD) which is maintained at a predetermined temperature and which further demonstrates a higher gain and signal-to-noise ratio with greater stability at a predetermined temperature for enhancing sorting efficiency.
US10449565B2 Application device and application method
An application device and an application method capable of increasing the speed of a line-drawing application are provided. The application device includes a discharge device, a worktable, a drive device, and a control unit. A discharge member gives an inertial force to a liquid material inside a liquid chamber, thereby discharging the liquid material from a plurality of discharge ports at the same time and forming a plurality of droplets on an application object. The plurality of discharge ports are arranged in a nozzle along a straight nozzle arrangement line, and the nozzle arrangement line is aligned with a drawing direction in which a drawing line is to be drawn. The application device performs the line-drawing application by discharging the liquid material such that a plurality of liquid masses discharged from the plurality of discharge ports do not contact with each other prior to landing on the application object, and that the liquid material having landed along the nozzle arrangement line join together on the application object.
US10449564B2 Apparatus for automated production of a roll of waxed fabric
An apparatus for producing a roll of waxed fabric is provided, the apparatus comprising: a frame; a temperature controlled bath at an entrance end of the frame; a squeegee pressed against an exit side of the temperature controlled bath; a cooling tower adjacent the temperature controlled bath, the cooling tower including walls and a manifold to define a cooling zone, the manifold for delivering a flow of air to the cooling zone, a tower roller rotatably mounted above the cooling zone and a lower roller rotatably mounted proximate an exit side of the cooling tower; a blower for delivering air to the manifold; a collection roller rotatably mounted adjacent the alignment roller; a driver roller in rolling engagement with the collection roller; and a motor in mechanical communication with the driver motor for driving the driver motor. A method of producing a roll of waxed fabric is also provided.
US10449562B2 Adjustable arc of coverage cone nozzle rotary stream sprinkler
A cone valve assembly including an upper valve member with a conical top portion and a stepped and spiraled top surface and a lower valve member including a central opening with a stepped and spiraled valve surface surrounding the central opening. The upper valve member is mounted in the lower valve member such that the lower valve member is rotatable and axially movable relative to the upper valve member. Rotation of the lower valve member allows for the adjustment of an arcuate slot opening that provides a conically shaped discharge stream of water from the cone valve nozzle assembly directly onto the rotating distributor to provide the desired arc of sprinkler coverage.
US10449559B2 Combined shower head with cool water discharging function
Disclosed is a combined shower head with cool water discharging function, which comprises two shower heads; the first shower head is disposed with an inlet passage, a first outlet portion and a first water diversion passage connected to the first outlet portion, the second shower head is disposed with a second outlet portion; the first shower head is further disposed with a water supply passage, a cool water discharging passage connected to the inlet passage, a temperature sensing component disposed in the cool water discharging passage and a control mechanism, the control mechanism is coupled to the inlet passage and the water supply passage to control the connection and disconnection of the inlet passage and the water supply passage. The present invention has advantages: the structure is simple, compact and low cost; the user can assemble the shower head fast and conveniently.
US10449556B2 Centrifuge having a compressor cooling device, and method for controlling a compressor cooling device of a centrifuge
The present invention relates to a centrifuge having a compressor cooling device and it also relates to methods for controlling a compressor cooling device of a centrifuge. The centrifuge according to the invention has a controllable throttle device in the refrigeration cycle of the compressor cooling device.
US10449555B2 Centrifugal separator with annular piston for solids extrusion
A centrifugal separator includes a cylindrical bowl, a core tube assembly, and an annular piston disposed around the core tube assembly and inside the inner surface of the bowl. Feed liquid is injected down the core tube assembly into the lower portion of the bowl, raising the annular piston. During a separation mode, the bowl rotates at high speed, separating solids from the feed liquid to accumulate along the inner surface of the bowl, while collecting clarified centrate as it exits the top of the bowl and through the core tube assembly. Following solids accumulation, bowl rotation is stopped and residual liquid is pumped from the bowl. In a solids discharge mode, the annular piston is urged downward along a vertical axis in response to compressed gas. The downward movement of the piston forces accumulated solids from the bowl via an opening in the lower end thereof.
US10449553B2 Magnetic biological entity separation device and method of use
The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed methods separate biological entities with magnetic labels by using a magnetic device. The claimed methods further include processes to dissociate biological entities magnetic conglomerate after magnetic separation.
US10449552B2 Home appliance having a filter
A household appliance can include a tub at least partially defining a treating chamber for holding liquid with an access opening, a nozzle emitting liquid into the treating chamber, a recirculation circuit fluidly coupling the treating chamber to the nozzle. The recirculation circuit can include a recirculation pump and a filter having a housing with an inlet and an outlet, ferrite particles located within the housing, and a magnet having a first operational state and a second operational state.
US10449551B2 Magnetic filter with drain and removable external magnetic element
A magnetic filter (10) for a central heating system is disclosed, the filter (10) including a connection assembly (12), a canister (14), and a magnetic element (16), the connection assembly (12) including an inlet (24) and an outlet (26) for connection to a central heating circuit; the canister (14) having an interior separation chamber which is fluidly connected with the inlet (24) and outlet (26) for allowing fluid to flow into the inlet (24), through the separation chamber, and out of the outlet (26); and the magnetic element (16) being removably positionable on the outside of the canister (14), the canister (14) and the connection assembly (12) forming a sealed flow path comprising the inlet (24), the interior separation chamber and the outlet (26), and the connection assembly (12) further including a closable drain outlet (28b) for draining fluid and magnetic particles from within the canister (14), internally of the magnetic element (16).
US10449550B2 Sorting device and sorting method
The present invention provides a sorting device and a sorting method for sorting a magnetically attractable substance and a non-magnetically attractable substance from a sorting target using a high gradient magnetic separator.
US10449548B2 Grinding and drying plant
A method for producing a comminuted dry material from a coarse material, the method including: (a) providing a heated drying gas from a drying gas source; (b) providing the coarse material in a storage bin; (c) feeding the coarse material and the heated drying gas into a comminuting equipment; (d) comminuting and drying the coarse material within the comminuting equipment to obtain a comminuted dry material; (e) collecting a mixture of drying gas and comminuted dry material from the comminuting equipment and feeding the mixture to a separator to separate the comminuted dry material from the drying gas; and (f) recycling at least part of the drying gas from step (e) as a preconditioning gas and feeding the preconditioning gas into a lower part of the storage bin to precondition the coarse material.
US10449547B2 Preparation of a powdery pharmaceutical composition by means of cryo-milling
A method for the preparation of a powdery pharmaceutical composition composed of a pharmaceutical excipient and a pharmaceutical component, among other possible ingredients, wherein the pharmaceutical excipient is a polyalkylene glycol, the method involving grinding a mixture of the pharmaceutical excipient and the pharmaceutical component at a temperature below ambient temperature.
US10449546B2 Shredder bin-full device
A paper shredder bin-full sensor with a push bar, a conductive element coupled to the push bar, a sensing contact assembly normally set apart from the conductive element, and a signaling contact coupled to the sensing contact assembly. Sensor includes a push bar sweeper between the conductive element and the push bar, and a biasing element coupled to the push bar sweeper, the biasing element elastically resists the shredded material force. A predetermined shredded material force presses the push bar, causing the conductive element to couple to the sensing contact assembly, in turn causing a waste bin-full signal to emanate. Push bar can be articulated and non-articulated. Articulated push bars include upper and lower push bars, and respective tensioning element connecting the respective upper and lower push bars. Lower push bar is extended from upper push bar. Paper shredder can have articulated or non-articulated push bars.
US10449542B2 Electrochemical metabolic activity detecting device
Methods and devices for detecting metabolic activity of target cells in a sample. The target cells are concentrated in a nanoliter well having a microfilter. A reporter compound that exhibits a change in electrochemical state in response to metabolic activity of the target cells is introduced. Metabolic activity or viability of the target cells is detected based on a determined change in the electrochemical state of contents in the well.
US10449541B2 Microfluidic device
There is provided a microfluidic device comprising: a plurality of wells, each well having an inlet and an outlet, wherein the inlets are in fluid communication with one or more entry channels and the outlets are in fluid communication with one or more exit channels, wherein said outlet is connected to the exit channel via an outlet connecting channel and said inlet is connected to the entry channel via an inlet connecting channel wherein the dimension of the outlet connecting channel is configured such that the surface tension of a liquid comprised in the well prevents the release of the liquid through the outlet connecting channel. There is also provided a system, method and use of the device.
US10449539B2 Immuno histo chemistry tissue processing system and cartridge therefor
A fluid-containing cartridge for a tissue processing apparatus includes a body defining a plurality of discrete fluid passageways, and a plurality of fluid-containing wells that are disposed on the body, wherein each fluid passageway of the body defines a fluid path between one of the fluid-containing wells and a fluid exit port that is configured to dispense fluid onto a laboratory slide.
US10449537B2 Capillary manipulation of clinical samples
A system for collection and delivery of sub-milliliter liquid samples is described that provides a dramatic simplification for the measurement of clinical values. The system produces high dilutions of capillary size samples, such as bodily fluids or blood, by a factor of 1000 or more. Multiple assays can be conducted on a sample of 0.1 cc or less. A small lancet can create a drop of blood on a fingertip or other location, which can be collected into a self-priming capillary blood collector. The sample is then loaded into a consumable loader. Then a fluid, such as saline, is flowed into the consumable loader, and passes through the capillary collector, washing out the fluid. Downstream, the blood in the capillary is reliably diluted by mixing with appropriate reagents to allow analysis of selected blood properties. One or more individual bubbles can be inserted into the stream during loading. The capillary loading system can be used for one or several assays on a single blood sample. It can be very compact and lightweight and is suitable for use in remote environments, such as outer space, in which it is difficult to access diagnostic assays.
US10449534B2 Control unit for pipetting machines
A control unit for controlling a pipetting machine a pipetting machine, and a method for controlling a pipetting machine, wherein the control unit controls at least one actuator for moving a pipetting device between receptacle units for liquids to be pipetted and for receiving or dispensing liquids to be pipetted. The control unit, by selecting one or more graphic receptacle unit equivalents which correspond to receptacle units, assigns at least one transfer parameter to the receptacle unit equivalents. The transfer parameter corresponds to a transfer volume, which is to be received from the receptacle unit corresponding to the respective receptacle unit equivalent or is to be dispensed into the receptacle unit corresponding to the respective receptacle unit equivalent. The control unit is additionally designed so that selected source receptacle unit equivalents are simultaneously assignable to multiple target receptacle unit equivalents.
US10449533B2 High capacity adsorbent for fluoride ion and oxyanions of phosphorous and arsenic and method for making the same
An alumina-based adsorbent and method of making exhibiting high affinity and capacity towards fluoride ions and oxyanions of phosphorus and arsenic in a broad pH range and presence of large excess of competitive ions. Alumina based adsorbent is a mixed oxide of alumina existing in tetra-, penta-, and octahedral coordination at specific ratio, and oxides of polyvalent metals of elements titanium, zirconium, tin, cerium, lanthanum, iron, or combinations thereof. The alumina based adsorbent may be used for selective removal of fluoride ion and oxyanions of phosphorus and arsenic from drinking water, industrial streams and wastes, in medicine and food industry.
US10449526B2 High charge density metallophosphate molecular sieves
A new family of highly charged crystalline microporous metallophosphate molecular sieves has been synthesized. These metallophosphates are represented by the empirical formula of: Rp+rA+mM2+xEyPOz where A is an alkali metal cation, R is at least one quaternary organoammonium cation, M is a divalent metal such as zinc and E is a trivalent framework element such as aluminum or gallium. This family of high charge density metallophosphate materials are among the first metalloalumino(gallo)phosphate-type molecular sieves to be stabilized by combinations of alkali and quaternary organoammonium cations, enabling unique compositions. This family of high charge density metallophosphate molecular sieves has catalytic properties for carrying out various hydrocarbon conversion processes and separation properties for separating at least one component.
US10449522B2 Process for manufacture of NOx storage materials
Processes for manufacturing nitrogen oxide storage materials and lean NOx trap catalysts are disclosed. Also disclosed are nitrogen oxide storage material made by processes comprising barium carbonate (BaCO3) and ceria (CeO2) by using Ba(OH)2 instead of most or all Ba(OOCH3)2 to reduce cost and reduce harmful byproducts. Aspects of the present invention also relate generally to lean NOx trap (LNT) comprising nitrogen oxide storage materials.
US10449513B2 Wastewater purification with nanoparticle-treated bed
Nanoparticle-treated particle packs, such as sand beds, may effectively filter and purify liquids such as waste water. When tiny contaminant particles in waste water flow through the particle pack, the nanoparticles will capture and hold the tiny contaminant particles within the pack due to the nanoparticles' surface forces, including, but not necessarily limited to van der Waals and electrostatic forces. Coating agents may help apply the nanoparticles to the particle surfaces in the filter beds or packs.
US10449509B2 Synthesis of organic peroxydes using an oscillatory flow mixing reactor
The present invention concerns a method and an apparatus (10, 20) for a continuous preparation of organic peroxides, with the reactor comprising at least one flow channel (1, 1a, 1b) configured as a reaction zone; an inlet system (2) in fluid communication with a first end of the at least one flow channel and configured for introducing two or more substances or a combination of substances into the at least one flow channel; an outlet system (3) in fluid communication with a second end of the at least one flow channel, the second end being located downstream of the first end and the outlet system being configured for extracting a reaction product present at the second end; an oscillatory system (4, 5) configured for superimposing an oscillatory flow on the flow of substances passing through the at least one flow channel, the oscillatory being effected in at least a section of the at least one flow channel; and a controller configured to implement the method by controlling the inlet system to introduce, according to a first time characteristic, at least two substances or a combination of substances into the at least one flow channel, the oscillatory system to superimpose an oscillatory flow on at least a part of the flow of substances passing through the at least one flow channel, and the outlet system to extract, on an ongoing basis, the reaction product formed in the flow channel from the substances introduced such that the output mass flow rate corresponding to the sum of the input mass flow rates.
US10449503B2 Temporary addition or injection system
A temporary addition or injection system installed without the need for civil work comprising: one or more silos mounted on a trailer; optionally one or more transfer pots; and one or more control systems, wherein the one or more transfer pots and the one or more control systems are either (a) directly or indirectly connected to the one or more silos mounted on the trailer or (b) mounted adjacent to the one or more silos mounted on the trailer.
US10449502B2 Methods for analyzing hydrocarbons and hydrocarbon blends for chemical compositions
The present invention is generally related to the analysis of chemical compositions of hydrocarbons and hydrocarbon blends. This method, in particular embodiments, may apply specifically to the problem of analyzing extremely complex hydrocarbon-containing mixtures when the number and diversity of molecules makes it extremely difficult or impossible to realistically identify and quantify them individually in a reasonable timeframe. Particular SEC (size exclusion chromatography)-based methods and apparatus disclosed herein may be used to measure, e.g., the molecular size, weight, and/or volume, whether in absolute or relative manner, of the various components of eluate from the SEC stationary phase (e.g., a permeable gel). This analytical method is applicable on a wide variety of hydrocarbonaceous materials, and especially useful for, but not limited to oil, maltenes of oil, asphalt binders and asphalt binder blends, which may contain wide varieties of different types of additives, modifiers, and chemistries.
US10449498B2 Continuous kneading device
A continuous kneading device including a pair of kneading rotors, capable of increasing mesh between the kneading rotors while also suppressing a kneading load applied to the kneading rotors. The continuous kneading device including a barrel and a pair of kneading rotors housed in the barrel. The kneading rotors rotate in mesh in directions different from each other. Each kneading rotor includes a plurality of kneading flights for kneading a material supplied into the barrel. The material is fed axially from the upstream kneading section to the downstream kneading section to be sequentially kneaded. The kneading flight constituting the downstream kneading section has a rotational outer diameter larger than a rotational outer diameter of the kneading flight constituting the upstream kneading section.
US10449494B2 Method for determining the true amount of an active product entering a catalytic device of an exhaust line of a vehicle
Method for determining a true amount of active product entering a catalytic device of a vehicle exhaust line includes: introducing, into the exhaust gas stream upstream of the device, an active flow rate of active product so that the contaminant and active product are absent at the measurement probe at the outlet of the device, increasing the active flow rate until the second probe measures a given escape content of the product, stabilizing the escape of product, via the measurement provided by the probe, at the given escape content, introducing a theoretical additional test flow rate of product into the exhaust gas stream upstream of the device, waiting until the total content of product measured in response at the second probe has stabilized, and measuring this stabilized total content, and determining the stabilized true additional test flow rate of active product entering the device.
US10449493B2 Processing apparatus equipped with catalyst-supporting honeycomb structure, and method for manufacturing same
A processing apparatus equipped with a catalyst-supporting honeycomb structure, which is characterized in that corrugated plate-like glass fiber papers having a functional catalyst supported thereon and flat plate-like glass fiber papers having the same functional catalyst supported thereon are alternately laminated without being bonded to each other, to form a catalyst-supporting honeycomb structure, and this catalyst-supporting honeycomb structure is packed in a casing.
US10449487B2 Mercury control in a seawater flue gas desulfurization system
A method for controlling mercury release, emission and/or re-emission levels in a treated flue gas and a seawater effluent waste stream through control of a sulphite concentration within a seawater scrubber system is disclosed. One method for controlling mercury release, emission and re-emission levels through control of sulphite concentration is to measure the sulphite concentration of seawater entering a seawater scrubber system and comparing the same to a predetermined sulphite concentration value. If the comparison reveals the measured sulphite concentration is above the predetermined sulphite concentration values, the amount of fresh seawater and/or oxidation air supplied to the seawater scrubber system is increased. If the comparison reveals the measured sulphite concentration is below the predetermined sulphite concentration values, the amount of fresh seawater and oxidation air supplied to the seawater scrubber system is decreased.
US10449482B2 Use of expansion machines in gas scrubbers
A method for operating a gas scrubber is disclosed in which components are removed from a crude gas by scrubbing with a chemical or physical scrubbing medium to obtain a pure gas present at elevated pressure which, after heating, is introduced into an expansion machine which after work-performing decompression the pure gas leaves at an exit temperature. The amount of heat supplied to the pure gas during heating thereof is deliberately altered to approximate the exit temperature thereof to a predetermined target value at all times.
US10449474B2 Filter media including a waved filtration layer
Filter media including a waved filtration layer are described herein. The filtration layer may be held in a waved configuration by a support layer. In some cases, the filtration layer may have a combination of characteristics (e.g., mean flow pore size, basis weight, amongst others) that can lead to enhanced filtration performance (e.g., reduced air permeability decrease), in particular, in high humidity environments. The filter media may be used to form a variety of filter elements for use in various applications.
US10449469B2 Oil extraction aids in bioproduct production
A method is provided for the use of a process additive system to improve the recovery of oil from a process stream generated in a bioproduct production process.
US10449466B2 Spinner having detachable base and stand therefor
The present invention is a spinner device adapted for use as a toy or amusement device and in relieving stress. The spinner device preferably includes a plurality of radially extending arms, each arm having a magnetic mass therein and being magnetically mass adjustable. The spinner device preferably includes a magnetically attachable and detachable base device that allows the spinner device to function as a top. The spinner device further preferably includes a magnetically attachable and detachable display stand device that allows the spinner device to be rotated or spun while being displayed.
US10449459B2 Information processing system, server device, and recording medium
An example system includes an imparting part imparting value information to a user of each information processing device; and a joint information processing part performing information processing in accordance with joint operation of a user of one of the information processing devices and a user of another information processing device through a network. When a given imparting condition has been satisfied in accordance with information processing having been performed by the joint information processing part, the imparting part imparts the value information.
US10449457B2 System and method for dynamic matchmaking population herding
Techniques are disclosed for dynamically herding a matchmaking population for a multi-player game. A new player requesting to play a multi-player game is presented with a gameplay selection mode interface based on metrics gathered by monitoring the matchmaking population for the different gameplay modes of the multi-player game. The metrics are evaluated by a metric evaluation engine to determine a configuration of the gameplay mode selection interface that is designed to herd the matchmaking population to evenly balance the players across the different gameplay modes of the multi-player game. A herding incentive may be determined based on the evaluation of the metrics and included in the gameplay mode selection interface.
US10449451B2 Video game with steering assist that considers proximity to a course edge
In an example game processing of moving a predetermined object in a predetermined course in a virtual space on the basis of an operation performed by a player, first, an input amount according to an input for controlling a moving direction of the predetermined object based on the operation performed by the player is obtained. Next, the input amount according to the input for controlling the moving direction is corrected so as to cause the moving direction of the predetermined object to be close to a direction along a travelling direction as a direction toward a destination, by increasing/decreasing a predetermined correction value which is added to the input amount, on the basis of relationship between a current moving direction of the predetermined object and the travelling direction of the course. Then, movement of the predetermined object is controlled on the basis of the corrected input amount.
US10449445B2 Feedback for enhanced situational awareness
An electronic game feedback system includes a display device, a sensor system, and a feedback device. The display device is configured to provide a display of a virtual environment associated with an electronic game to a user. The display device at least partially obstructs the view of the user of a physical environment surrounding the user. The sensor system is configured to acquire object data regarding an object located within the physical environment. The feedback device is configured to provide feedback to the user based on the object data and indicative of a location of the object relative to the user.
US10449441B2 Notifying users of options to participate in meta games
In a method of notifying a user of an option to participate in a meta game, a presence of a player of a computer-implemented game at a location is detected. An association between a computer-implemented meta-game and the location is identified. The player of the computer-implemented game is presented with an option to participate in the computer-implemented meta-game. An indication of an acceptance of the option to participate in the computer-implemented meta game is received from the player of the computer-implemented game. A performance of an action within the computer-implemented game by the player of the computer-implemented game is reflected within the computer-implemented meta game.
US10449438B2 Toy top
A toy top includes a body and a bump for attack which is disposed on a circumference of the body. The bump moves up and down according to a force acting on the bump while the toy top spins.
US10449431B1 Basketball training device
A basketball training device that helps a basketball player learn where to aim when taking a shot including one or more targets that are secured to a basketball rim by an attachment mechanism.
US10449428B2 Golf club heads and methods to manufacture golf club heads
Embodiments of golf club heads, golf clubs, and methods to manufacture golf club heads and golf clubs are generally described herein. In one example, a golf club head may include a body portion comprising a first material. The body portion may have a toe portion, a heel portion, a top portion, a sole portion, a back portion, a front portion having a face portion. The golf club head may include an interior cavity partially, substantially, or entirely filled with a first filler material and a second filler material. Other examples and embodiments may be described and claimed.
US10449427B2 Golf club heads with ribs and related methods
Provided herein are embodiments of golf club heads comprising a crown and a ribbed region. The ribbed region of the golf club head can be positioned on a portion of the crown and can further include a ribbed wall, wherein the ribbed wall comprises a ribbed wall interior surface, a ribbed wall exterior surface, and one or more external ribs. The one or more external ribs can protrude from the ribbed region to increase the strength of the crown and beneficially reduce crown thickness. Other embodiments and related methods are disclosed herein.
US10449426B2 Golf clubs and golf club heads with removable dampening member in sole
Ball striking devices, such as golf clubs, have a head that includes a face having a striking surface configured for striking a ball, and a body connected to the face and extending rearwardly from the face, with the body having a crown, a sole, a heel side, and a toe side, such that the face and the body combine to define an enclosed internal cavity. A damping member is connected to the body and includes a post extending inwardly into the cavity from an inner surface of the body, a first arm extending from the post toward the heel side of the body, and a second arm extending from the post toward the toe side of the body. The damping member is configured to produce a mass damping effect upon an impact on the face.
US10449422B2 Couplings for securing golf shaft to golf club head
A coupling for securing a golf shaft to a golf club head includes a first component configured to contact, and engage with, the golf shaft, and a second component bonded to the first component and configured to space the first component from the golf club head. The second component includes a second material having a Young's modulus less than a first material of the first component. In another aspect, a coupling includes a shaft engagement element, and a spacer configured to space the first component from the golf club head so that the golf shaft is above the golf club head in its entirety. The spacer includes a material having a Young's modulus no greater than about 10 Gpa. In another aspect, a kit includes a first coupling and a second coupling with at least one of a structural configuration or a material of a vibration dampening element differing.
US10449419B1 Swim fin assembly
A swim fin assembly for increasing propulsion during swimming includes a sleeve that is worn around a lower leg while swimming. A plurality of fins is each hingedly coupled to the sleeve. Each of the fins is urged into a deployed position on a downstroke of the lower leg during swimming. In this way each of the fins frictionally engage water thereby increasing thrust generated on the downstroke. Each of the fins is urged into a stored position on an upstroke of the lower leg during swimming to resist frictionally engaging the water thereby reducing drag on the upstroke.
US10449418B2 Bouncing device that is vertically oriented and centrifugally balanced
A handheld bouncing device that is vertically oriented and centrifugally balanced including: (a) an elongated, compressible axle; (b) a planar body having a balanced symmetrical shape and a central aperture, the elongated compressible axle disposed within the central aperture such that a middle section of the elongated compressible axle is rotationally coupled to the planar body, such that the elongated compressible axle protrudes from the central aperture perpendicular to a plane of the planar body.
US10449404B2 Exercise apparatus
An exercise apparatus includes first, second, third and fourth elongated frame members respectively defining a first, second, third, and fourth frame portion each comprising interior and exterior perimeters. The first frame member can include first, second, third, and fourth segments. The first frame portion can encompass first and second open interior regions. The third frame member can adjoin the first frame member at spaced first and second points on the first frame member and span from the first point to the second point. The fourth frame member can adjoin the first frame member at spaced third and fourth points on the first frame member and span from the third point to the fourth point.
US10449399B2 Horizontal lifeline system and method of adjusting a horizontal lifeline system
A horizontal lifeline system includes a first termination arrangement structured to attach to a first anchor point, a second termination arrangement structured to attach to a second anchor point, a horizontal lifeline cable coupled to the first termination arrangement, a rope length adjuster attached to the horizontal lifeline cable and having a housing through which the horizontal lifeline cable can be pulled to adjust the length of the horizontal lifeline system and apply tension to the horizontal lifeline cable, and a tension limiting ratchet coupled between the second termination arrangement and the rope length adjuster and being structured to be ratcheted to increase tension applied to the horizontal lifeline cable and to provide an indication and deter further ratcheting when the tension applied to the horizontal lifeline cable reaches a predetermined tension limit.
US10449396B2 Personal height rescue apparatus
There is provided height rescue apparatus comprising a casing which incorporates a bracket for attachment to a harness. The bracket can be releasably attached to a load element which is attached to a safety line which in turn can be attached to a secure anchorage. There is also a release means in the form of a pull cord for releasing the load element from the bracket after a fall and speed control means for controlling the rate of deployment of an elongate element stored within the casing and thus controlling the descent of a user.
US10449395B2 Rib identification for transcostal focused ultrasound surgery
A method for transcostal ultrasound treatment of tissues includes determining rib locations, e.g., based on ultrasound reflections off the ribs or acoustic radiation force signals, and transcostally focusing ultrasound into the tissue while minimizing damage to the ribs.
US10449393B2 Radiation systems with minimal or no shielding requirement on building
A radiation system includes a support, a capsule rotatably coupled to the support, a radiation source movably coupled to the capsule, wherein the radiation source is configured to provide a treatment radiation beam, and is capable of being turned on or off in response to a control signal, and a collimator located next to the radiation source, wherein the capsule defines a space for accommodating a portion of a patient, and includes a shielding material for attenuating radiation resulted from an operation of the radiation source, and wherein the shielding material is configured to limit a radiation exposure level to 5 mR/hr or less within 5 meters from an isocenter.
US10449391B2 System and method for reducing biological damage in proton therapy
Systems comprising a processor in electrical communication with a tangible, non-transitory memory that, in response to an execution by the processor, cause the processor to measure a relative biological effectiveness of a beam on a region of a human body, and a beam applicator in electrical communication with the processor, wherein a characteristic of the beam can be adjusted based on the measured relative biological effectiveness are disclosed. Methods of treatment comprising measuring, by a processor capable of detecting potential biological hot spots, a relative biological effectiveness of a beam on a region of a human body, designing a beam therapy treatment plan based on the measured relative biological effectiveness, and applying a beam to a patient with a region in need of beam therapy with a beam applicator in electrical communication with the processor capable of detecting potential biological hot spots are also disclosed.
US10449388B2 Systems and methods for specifying treatment criteria and treatment parameters for patient specific radiation therapy planning
Disclosed herein are systems and methods for specifying treatment criteria and treatment planning parameters for patient specific radiation therapy planning. According to an aspect, a method includes receiving data about a patient, computing geometric characterization of one or more organs at risk proximate to a target volume of a patient or vice versa, and selecting relevant treatment knowledge and experience. The method also includes generating, based on the received data, computed geometric characterization, and available knowledge and experience, a first set of radiation treatment planning parameters that will lead to a high quality plan for the patient. Further, the method includes model-based prediction, based on the data, a second set or more of radiation treatment planning parameters that will lead to alternative achievable plans with different organ sparing objectives for treating the patient. The multiple sets for parameters can be used separately or in conjunction to generate treatment plans.
US10449386B2 Method for optimizing a brachytherapy radiation treatment plan
A control circuit optimizes a brachytherapy radiation treatment plan for a patient target volume by defining a radiation-control structure that conformally surrounds the patient target volume and then automatically removes part, but not all, of the radiation-control structure to control consideration of radiation sources that are not disposed within the patient target volume. By one approach the control circuit selectively removes parts of the radiation-control structure as a function of the geometry as corresponds to placement of one or more of the radiation sources. For many application settings it serves well for the radiation-control structure to represent a radiation-avoidance area.
US10449385B2 Radiation therapy device and quality control method for radiation therapy device
An embodiment of the present invention provides a radiation therapy device including: a main body; a gantry coupled to a side of the main part and rotatable relative to the main part in at least one direction; a radiation head provided on a side of the gantry to emit radiation; an image acquisition unit facing the radiation head to detect radiation emitted from the radiation head and obtain images by converting the detected radiation into electric signals; and a reference image acquisition frame provided on a side of the radiation head and including a plurality of markers formed thereon.
US10449382B2 Implantable neural modulation device
An implantable subsystem includes multiple implantable neural probes disposed on a flexible substrate. Each neural probe is configured to magnetically stimulate brain neurons. Each probe includes an array of magnetic neural stimulators that magnetically stimulate neurons. Each probe also includes neural probe activation circuitry comprising thin film switches disposed on the flexible substrate. The thin film switches are electrically coupled to row and column activation lines and selectively activate the magnetic neural stimulators in response to neural stimulation activation signals carried on the activation lines.
US10449381B2 Light-magnetism providing apparatus
A light-magnetism harmonizer is provided, including: a shell body, defining a space and including a magnetism-shielding layer outside the space; a light generator, attached to the shell body, emitting light into the space; a magnetic unit, attached to the shell body and located by an inner side of the magnetism-shielding layer, part of magnetic line of force of the magnetic unit going outwardly being shielded by the magnetism-shielding layer, part of magnetic line of lines of the magnetic unit going inwardly into the space.
US10449380B2 Defibrillator
Several defibrillators, defibrillator architectures, defibrillator components and methods of operating defibrillators are described. In one aspect, a defibrillator (as for example an automated external defibrillator) that can be powered by a mobile communication device such as a smart cellular phone or a tablet computer is described. Utilizing a phone (or other mobile communication device) as the power supply for an external defibrillator allows the external defibrillator to be smaller and, in some circumstance, removes the need for a battery that stores sufficient energy for shock delivery—which would need to be checked and/or replaced on a regular basis. Additionally, when desired, certain control functionality, computation, data processing, and user instructions can be handled/presented by the mobile communications device thereby further simplifying the defibrillator design and improving the user experience. This architecture takes advantage of the nearly ubiquitous availability of smart phones, tablet computers and other mobile communication devices.
US10449370B2 Network-accessible data about patient with wearable cardiac defibrillator system
A data file system includes one or more files about a patient wearing a wearable cardiac defibrillator (WCD) system that has been assigned to them. The one or more files contain at least one patient identifier of the patient, compliance data about a history of the patient's wearing the WCD system, and possibly other data. The data file system can be accessed through a communication network when the patient uses a communication device. When so accessed, some of the contents can be viewed on a screen of the device, for example in the form of a website. In embodiments, the health care provider and friends and family can view such data and even enter inputs, which may create a situation that motivates the patient to comply better.
US10449364B2 Pacemaker mediated tachycardia detection and intervention
A method of employing an implantable medical device to detect pacemaker mediated tachycardia (PMT) and adjusting a parameter (e.g. PVARP) in response to confirmation of the PMT. The method comprises, with a processor located in the implantable medical device, (1) measuring a first Vp-As (VA1), (2) lengthening SAV by 50 ms for 1 beat in response to measuring VA1, (3) measuring a second Vp-As (VA2), (4) returning to a normal SAV, (5) measuring a third Vp-As (VA3), (6) determining whether VA1=VA2 and VA1=VA3, (7) in response to determining whether VA1=VA2 and VA1=VA3, confirming presence of PMT, and (8) in response to confirming presence of PMT, PVARP is extended.
US10449361B2 Systems and methods for treating cardiac arrhythmias
Systems and methods for coordinating treatment of abnormal heart activity using multiple implanted devices within a patient. In one example, abnormal heart activity may be sensed by a medical device system. One of the devices of the system may determine to deliver anti-tachycardia pacing therapy to the heart of the patient, and may communicate an instruction to another of the devices of the medical device system to deliver anti-tachycardia pacing (ATP) therapy to the heart. The receiving medical device may then deliver ATP therapy to the heart of the patient.
US10449360B2 Graphical user interface for programming neurostimulation pulse patterns
An example of a neurostimulation system may include a storage device, a programming control circuit, and a graphical user interface (GUI). The storage device may be configured to store individually definable waveforms. The programming control circuit may be configured to generate stimulation parameters controlling the delivery of the neurostimulation pulses according to a pattern. The GUI may be configured to define the pattern using one or more waveforms selected from the individually definable waveforms. The GUI may display waveform tags each selectable for access to a waveform of the individually definable waveforms, and display a waveform builder in response to selection of one of the waveform tags. The waveform builder may present a graphical representation of the accessed waveform and allow for the accessed waveform to be adjusted by editing the graphical representation of the accessed waveform on the GUI.
US10449359B2 Method and apparatus for improving cognitive performance
A method for delivering electrical stimulation to alter a cognitive state of a user, the method comprising: monitoring a brain signal from the user via one or more intracranial electrodes implanted in the brain of the user while the user is presented with a stimulus; comparing the brain signal to a testing phase biomarker, wherein the testing phase biomarker is derived from a cognitive test performed on a contributor during a testing phase; delivering electrical stimulation to a brain of the user based on the comparing step to steer the brain of the user towards a high performance cognitive state.
US10449357B2 Automatic determination of the threshold of an evoked neural response
Techniques for automatically analyzing neural activity within a target neural region. In one example, electrical stimulation is applied to the target neural region at an initial current level that approximates a typical threshold-Neural Response Telemetry (NRT) level. An NRT measurement of neural activity within the target neural region in response to the stimulation is recorded. A machine-learned expert system, which is configured with a decision tree that includes at least two levels of nodes which consider parameters relating to the NRT measurement, respectively, is utilized to predict, based on one or more features of the neural activity, whether the NRT measurement includes a neural response or does not include a neural response.
US10449355B2 Systems and methods for restoring muscle function to the lumbar spine and kits for implanting the same
A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include one or more electrode leads coupled to an implantable pulse generator (IPG) and a tunneler system for subcutaneously implanting a proximal portion of the lead(s). The system may also include a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.
US10449351B2 Valve for administration of multiple drug fluids
A drug administration valve (100) comprises a valve housing (200) having a plurality of drug inlets (D1 to D4) for receiving drug fluids, such as cytostatic, one flushing inlet (F) for receiving a flushing fluid, and an outlet (O). A valve member (300) rotationally arranged in the housing has a passageway (320; 321) presenting a single inlet (322) and a single outlet (324). The valve member (300) presents a plurality of drug positions for guiding an associated drug fluid to the outlet (O), and one or more flushing positions for guiding a flushing fluid through the same passageway (320; 321) as the drug fluids in order to flush said passageway (320; 321) from any drug residuals. The valve member (300) is prevented from rotating from one drug position to another drug position without passing one of said flushing positions.
US10449348B2 Devices and methods for enhancing the topical application of a benefit agent
The present invention relates to devices and methods for treating, reducing and preventing adverse skin/scalp conditions and enhancing the topical application of a benefit agent. The devices are ultrasonic with transducers positioned at an angle other than 90° relative to the surface at which the ultrasound is to be applied.
US10449342B2 Medical applicator
An applicator for administration of a medicament comprises a container in fluid communication with a dispenser having a plurality of non-deformable structures configured for retaining a predetermined volume of a liquid medicament delivered from the container. The dispenser is capable of delivering at least a part of said predetermined volume of said liquid medicament to a surface upon contact therewith.
US10449335B2 Peelable protective sheath
A peelable protective sheath and related assemblies/systems and methods are disclosed. The protective sheath may be used on a balloon catheter to protect the balloon and any coating thereon. The protective sheath may be peelable to make removal of the protective sheath easier. The peelable protective sheath may be inserted into a hemostatic valve and introducer while still disposed over the balloon of a balloon catheter to protect the balloon and any bioactive coating thereon from damage during insertion. The peelable protective sheath may be peeled from a proximal end to initiate removal. Alternatively, the peelable protective sheath may be peeled from a distal end of the peelable protective sheath as the balloon catheter is inserted through a hemostatic valve and introducer.
US10449331B2 Catheter devices with seals and related methods
Needle devices are described. The needle devices can have a catheter hub, a needle hub, and a valve system for controlling fluid flow through the catheter hub. The valve system can include a valve and a valve retainer. The valve can have flow holes for fluid flow therethrough or can have a valve piece for controlling flow through flow holes located externally of the valve. A needle guard is usable with the needle device to block a tip of the needle. A valve opener can also be used to open the valve.
US10449328B2 Packaged catheter assembly
A packaged catheter assembly includes a urinary catheter, a package, and a seal. The urinary catheter has a tube section connected between a proximal end and a distal end, and the proximal end of the urinary catheter is insertable into a urinary bladder. The package contains the urinary catheter and has a proximal compartment section that is removable from a distal section of the package to provide an outlet in the distal section of the package. The seal is arranged between an outer surface of the urinary catheter and an inner surface of the distal section of the package. The seal provides a nearly or truly liquid tight interface between the urinary catheter and the inner surface of the distal section of the package.
US10449324B2 Combined respiratory muscle training and oscillating positive expiratory pressure device
A respiratory treatment device for the combined administration of respiratory muscle training (“RMT”) and oscillating positive expiratory pressure (“OPEP”) therapy, and administration of RMT using pressure threshold resistors and flow resistors with respiratory treatment devices, such as OPEP devices.
US10449321B2 Gas delivery devices
A gas delivery device includes a nitric oxide generating system. The system has a medium including a source of nitrite ions. A working electrode is in contact with the medium. A Cu(II)-ligand complex is in contact with the working electrode. A reference/counter electrode is, or a reference electrode and a counter electrode are in contact with the medium and separated from the working electrode. An inlet conduit is to deliver nitrogen gas to the medium, and an outlet conduit is to transport a stream of nitrogen gas and nitric oxide from the medium. An inspiratory gas conduit is operatively connected to the outlet conduit to introduce an oxygen-containing gas and form an output gas stream of the gas delivery device.
US10449316B2 Mask with red mark alleviating pocket
A patient interface device that overcomes the shortcomings of conventional patient interface devices is provided. One embodiment of the patient interface device provides a cushion for a patient interface device that includes a first end portion structured to contact a portion of a patient's face. The first end portion includes an inner, first surface, an outer, second surface and at least one pocket disposed between the first end portion first surface and the first end portion second surface.
US10449313B2 Ultrasound scanning apparatus, breathing machine, medical system and related method
An ultrasound scanning apparatus, a breathing machine, a medical system and a related method. The ultrasound scanning apparatus comprises an ultrasound scanning unit, an ultrasound controller for controlling the operation of the ultrasound scanning unit, detecting the operation state of the ultrasound scanning unit, generating a first enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from an operating state to a nonoperating state and generating a second enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from the nonoperating state to the operating state, and an enable output end for transmitting the first enable signal or the second enable signal to the breathing machine to control the running of the breathing machine.
US10449312B2 Methods and apparatus for the systemic control of ventilatory support in the presence of respiratory insufficiency
A method and apparatus for providing ventilatory assistance to a spontaneously breathing patient. An error signal is computed that is the difference between a function of respiratory airflow over a period of time and a target value. Using a servo loop, air is delivered to the patient at a pressure that is a function of the error signal, the phase of the current breathing cycle, and a loop gain that varies depending on the magnitude of the error signal. The loop gain increases with the magnitude of the error signal, and the gain is greater for error signals below a ventilation target than for error signals above the ventilation target value. The target value is an alveolar ventilation that takes into account the patient's physiologic dead space.
US10449310B2 Security features for an electronic metered-dose inhaler system
Security features for an electronic metered-dose smart inhaler, mobile app, and cloud-based software system that validates users and inhaler use protocols, such as medical prescriptions and clinical trial regimens. The smart inhaler interacts with a mobile app to control and monitor per-dose usage and capture efficacy results and feedback from medical patients and clinical trial participants for review by prescribing physicians, clinical trial administrators, medicine formulators and artificial intelligence. While the smart inhaler system is well suited for aerosol medical marijuana products, it may be used to deliver and conduct clinical trials on any type of product suitable for aerosol administration including other types of medication and non-medical products, such as nicotine, herbal products, pain killers, sleep aids, dietary stimulants, dietary suppressants, etc. Many of the system-based innovations are not limited to aerosol inhalers, and may be applied more widely to other types of in-home, patient-administered products.
US10449306B2 Systems for fluid delivery with wicking membrane
A fluid reservoir system is provided. The fluid reservoir system includes a fluid reservoir that defines a chamber to receive a fluid, and the fluid reservoir includes an outlet. The fluid reservoir system includes a source of pressure to draw the fluid into the outlet and a wicking membrane is coupled to the fluid reservoir that covers the outlet.
US10449300B2 Plunger for syringes and syringes
A plunger for a syringe may include a plunger head for fluid dense limiting a fluid chamber of the syringe, and a piston rod fixed to the plunger head. The piston rod may be formed by longitudinally extending axial webs that have an outwardly radial extension from the longitudinal axis and lead into a common crossing section. A free activation edge, which radially protrudes the radial extension may be provided on the piston rod and engageable with a vibration activator of a hollow body of the syringe to emit an acoustic signal. A swinging arm body may be arranged between two axial webs and couple the activation edge with the crossing section such that in case of a vibration activation in an axial direction the swinging arm body has a radial swinging arm length between the activation edge and the crossing section of at least 40% of the radial extension.
US10449299B2 Injection device for dispensing a medicament
Injection device for dispensing a medicament, comprising: a cartridge module, a dispensing mechanism which is actuated to dispense the injectable preparation, a dose-setting mechanism for setting the dose at which the injectable preparation is dispensed when the dispensing mechanism is actuated, the dose-setting mechanism comprising: a housing part (11) in which at least part of the dispensing mechanism is received, a display sleeve (13) rotatable therein, and an insertion sleeve (15) that can be inserted into the housing part (11), wherein the insertion sleeve (15) has, on its outer face, a raised surface section (20) that is transparent at least in some areas, and the housing part (11) has a recess (25) which is open at its distal edge (24) and which receives the insertion sleeve (15) in a rotationally fixed manner from the direction of the open end of the recess (25), and insertion sleeve for an injection device, dose-setting mechanism for an injection device for dispensing a medicament, and method for assembling an injection device.
US10449297B2 Alignment of elongated particles in a particle delivery device
A device for delivery of particles into biological tissue includes at least one conduit and a propellant source fluidically coupled to the conduit and configured to deliver a propellant into the conduit. A particle source is configured to release elongated particles into the conduit, the elongated particles having a width, w, a length, l>w. The propellant source and the conduit are configured to propel the elongated particles in a collimated particle stream toward the biological tissue. An alignment mechanism is configured to align a longitudinal axis of the elongated particles to be substantially parallel to a direction of the particle stream in an alignment region of the conduit. The aligned elongated particles are ejected from the conduit and impact the biological tissue.
US10449294B1 Operating an infusion pump system
An infusion pump system can operate to control dispensation of medicine according to a closed-loop delivery mode and according to an open-loop delivery mode. In the closed-loop delivery mode, the system can determine user-specific settings. In the open-loop delivery mode, the system can determine insulin dosages for dispensation based at least in part on the user-specific settings that were determined during the closed-loop delivery mode.
US10449291B2 Pump clip for a fluid infusion device
A pump clip for a fluid infusion device is provided. The pump clip includes a mount. The mount includes wings defined on opposed sides of the mount, a first lock tab to couple the pump clip to the fluid infusion device and a lip. The pump clip includes a base coupled to the mount that defines a second lock tab that engages with the lip to retain the mount in a first position. The mount is pivotable about a first pivot axis into a second position in which the mount is spaced apart from the base. The pump clip includes a clip coupled to the base, the clip pivotable about a second pivot axis relative to the base between a first, clamped position and a second, released position to receive an article.
US10449287B2 Concentrate container for an extracorporeal blood treatment machine and a concentrate supply system for an extracorporeal blood treatment machine
A concentrate container for an extracorporeal blood treatment machine with a fluid inlet at a first end of the concentrate container and a fluid outlet at a second end of the concentrate container as well as at least one connector to hold a coupling fitting of a fluid conduit, wherein at least one connector is concave in shape and is positioned inside the container. A system for use with this concentrate container, in which the coupling fittings are convex in shape. A connection piece provides for disinfection of the system.
US10449286B2 Femoral arterial cannula capable of guiding bidirectional perfusion flow
The present invention relates to a cannula for femoral arterial bidirectional (a heart direction and a distal lower extremity direction) perfusion. The cannula, which has a cannula tube to be inserted into a blood vessel of the femoral artery, includes a perfusion guide channel formed as a concave part from a predetermined portion of an inner circumferential surface at an end of the cannula tube to the opposite end thereof in a length direction and further includes a through-hole provided at a boundary portion between the perfusion guide channel and the cannula tube in an end direction of the cannula tube, or includes a through-hole provided in a predetermined portion of an inner circumferential surface of an end of the cannula tube and a guide cover provided at an upper portion of the through-hole to cover the upper portion of the through-hole and guide perfusion. During surgery, perfusion proceeds towards the distal limb and thus blood may be stably supplied, and thus ischemia prevalence of the distal limb may be significantly reduced. Accordingly, the cannula can replace conventional techniques used for distal limb perfusion and may stably perform femoral arterial cannulation without technical difficulties such as complications or breakage of blood vessels.
US10449273B2 Apparatus and method for evacuating a system
The present invention relates to an apparatus (1) for evacuating a system (3), comprising a pump (5), the pump (5) being suitable for being in connection with the system (3) with its inlet (7), a pressure tank (11) and a directional control valve (13), the pump (5) transporting a medium out of the system (3) and the pressure tank (11) into an ambience when the pressure tank (11) is connected to its inlet (7), wherein the directional control valve (13) is configured to switch the pressure tank (11) from the inlet (7) to the outlet (9) of the pump (5) when a predefined criterion is fulfilled. The present invention further relates to a breast pump (31) device comprising an apparatus (1) for evacuating a system (3) and a receiving funnel (27) for receiving a breast of a woman.
US10449267B2 Self-assembling underwater adhesives
Compositions, methods, and kits are provided which involve novel fusion protein-based adhesives for use in medical and marine applications. In some aspects, the novel fusion proteins comprise an adhesive domain (e.g., derived from an adhesive protein of a marine organism) and an amyloid domain (e.g., derived from a bacterial amyloid protein). Also provided are copolymers and fibers of the fusion proteins.
US10449263B2 Devices for disinfection, deodorization, and/or sterilization of objects
A treatment chamber 102 in which an object may be disinfected, deodorized, and/or sterilized. A source 172 of Hydroxyl radicals is arranged to introduce treatment agents, including Hydroxyl radicals, into the chamber 102. Operable sources 172 include nebulizer, Fenton generator, and Hydrogen Peroxide in the presence of nanoparticle catalyst and UV light. Ozone may be applied as an additional treatment agent. A tablet dispenser 128 may optionally be included to introduce additional chemical treatment agents into the chamber 102. The entire treatment device 100A-O may be sized for placement and use at the point-of-use of an object to be sterilized, such as in a hospital to sterilize an endoscope component.
US10449256B2 Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer
The invention relates to a composition in the form of an injectable aqueous solution, the pH of which is between 6.6 and 7.8, including at least: a) a basal insulin, the isoelectric point pI of which is between 5.8 and 8.5; and b) a hydrophobized anionic polymer. In one embodiment, the compositions according to the invention also include a prandial insulin.
US10449253B2 Adsorption of fluorinated anesthetics within the pores of molecular crystals
A method of delivering or sequestering anesthetic agents by adsorption of such agents by porous partially fluorinated compounds which display high weight adsorption capacities. Such compounds have a non-covalent organic framework with a central ring, such as hexa, tetra, tri or di substituted benzenes which may be substituted or unsubstituted with alternating electron poor and electron rich groups such as tetra-, tri-, or di-fluorobenzenes, oligocyanobenzenes, oligochlorobenzene, and benzene, pirydone, triazole, pyrazole, pyridine, and substituted benzenes so that the compound forms a porous supramolecular structure; and adsorbs the anesthetic agent within the pores of a the compound.
US10449251B2 Anti-CTLA4 monoclonal antibody or its antigen binding fragments, pharmaceutical compositions and uses
The present invention belongs to the fields of tumor therapy and molecular immunology, and provides an anti-CTLA4 monoclonal antibody or antigen binding fragment thereof, a pharmaceutical composition thereof and use thereof. The monoclonal antibody of the present invention can block the binding of CTLA4 to B7, relieve the immunosuppression on the body by CTLA4, and activate T lymphocytes.
US10449249B2 Polysaccharide suitable to modulate immune response
Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
US10449248B2 Nutritional composition for improving the mammalian immune system
The invention relates to a nutritional composition comprising (a) at least 18 en % of proteinaceous matter; (b) at least 12 wt % of leucine, based on total proteinaceous matter; (c) a lipid fraction comprising at least a ω-3 polyunsaturated fatty acid selected from the group of eicosapentaenoic acid, docosahexaenoic acid, eicosatetraenoic acid and docosapentaenoic acid; (d) an immune modulator; for improving the immune function in a mammal, preferably a human.
US10449246B2 Subunit vaccine of porcine pseudorabies virus and preparation method
The present disclosure provides a PRV gB protein fragment, or a conservative variant or active fragment thereof, the gB protein fragment has a high level of expression, the subunit vaccine antigen prepared from the gB protein fragment has a better immune effect than a subunit vaccine antigen prepared from gB protein. The invention also provides a preparation method of a subunit vaccine by using the gB protein fragment alone, or the gB protein fragment together with gD protein. This vaccine has a simple preparation method and provides excellent protection against disease caused by the porcine pseudorabies virus.
US10449244B2 Zika RNA vaccines
Aspects of the disclosure describe compositions that comprise RNA polynucleotides having an open reading frame encoding one or more Zika virus antigens. Methods for preparing and using the compositions are also described.
US10449241B2 Interferon-β production modulating Listeria strains and methods for using same
Mutant Listeria bacteria that modulate interferon-β production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
US10449240B2 Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10449239B1 Peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10449237B1 Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
Bacterial strains are provided having at least one of a reduced size, a sialic acid coat, inducibly altered surface antigens, and expression of PD-L1 or CTLA-4 antagonists and/or tryptophanase. The bacteria may have improved serum half-life, increased penetration into tumors, increased tumor targeting and increased antitumor activity. The bacteria are useful for delivery of therapeutic agents that treat of neoplastic diseases including solid tumors and lymphomas.
US10449236B2 Treating seizure with recombinant alkaline phosphatase
The present disclosure provides a method of treating seizure in a subject having aberrant alkaline phosphatase activities, comprising administering a therapeutically effective amount of at least one recombinant alkaline phosphatase to the subject.
US10449231B2 Compositions and methods for dengue virus chimeric constructs in vaccines
Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells.