Document Document Title
US10300700B2 Elongate printhead having robust electrical assembly
An inkjet printhead includes: a rigid elongate carrier having an ink supply channel and a lower surface having a plurality of printhead chips mounted thereon; a rigid PCB attached to the lower surface of the carrier, the PCB extending a length of the carrier and projecting laterally beyond a sidewall of the carrier; a lead retainer attached to the sidewall of the carrier; and a plurality of leads extending upwardly from contact pads positioned along a longitudinal edge portion of the PCB, each lead being secured to the sidewall of the carrier via the lead retainer. The PCB supplies power and data to the printhead chips via electrical connections between the PCB and the printhead chips.
US10300695B2 Ink jet printer and ink jet head
An ink jet printer includes an ink jet head and an ink jet head control circuit supplying a control signal to control the ink jet head. The ink jet head includes a nozzle, an ink chamber, an actuator configured to change a pressure of the ink chamber to eject ink from the nozzle, a driver circuit that is connected to a signal line on which the control signal is supplied and configured to generate a drive waveform for driving the actuator according to the control signal, and a non-volatile memory connected to the signal line and configured to store information of the ink jet head. The ink jet head control circuit includes a drive control circuit connected to the signal line and configured to output the control signal to the signal line, and a non-volatile memory control circuit that accesses the non-volatile memory via the signal line.
US10300693B2 Printhead drop detectors
In some examples, a printhead drop detector comprises a plurality of drop detection units. Each drop detection unit may comprise a radiation source and radiation detector and may be to detect a drop passing through a sampling volume between the radiation source and the radiation detector. A radiation detector of a first drop detection unit and a radiation source of a second drop detection unit is arranged on a first side of the sampling volume; and a radiation source of the first drop detection unit and a radiation detector of the second drop detection unit is arranged on the second side of the sampling volume.
US10300690B2 Ink film constructions
An ink film construction including: (a) a first printing substrate selected from the group consisting of an uncoated fibrous printing substrate, a commodity coated fibrous printing substrate, and a plastic printing substrate; and (b) an ink dot set contained within a square geometric projection projecting on the first printing substrate, the ink dot set containing at least 10 distinct ink dots, fixedly adhered to a surface of the first printing substrate, all the ink dots within the square geometric projection being counted as individual members of the set, each of the ink dots containing at least one colorant dispersed in an organic polymeric resin, each of the dots having an average thickness of less than 2,000 nm, and a diameter of 5 to 300 micrometers; each ink dot of the ink dots having a generally convex shape in which a deviation from convexity, (DCdot), is defined by: DCdot=1−AA/CSA, AA being a calculated projected area of the dot, the area disposed generally parallel to the first fibrous printing substrate; and CSA being a surface area of a convex shape that minimally bounds a contour of the projected area; wherein a mean deviation from convexity (DCdot mean) of the ink dot set is at most 0.05.
US10300682B2 Cellulose ester multilayer interplayers
An interlayer structure having a cellulose ester layer for use in structural laminates is described herein. The cellulose ester layer provides rigidity and support to multilayer interlayers comprising an array of different layers. Due to the diverse properties of the cellulose ester layers, the present interlayers can be useful in producing structural laminates having high stiffness and which possess good optical clarity for a variety of applications, including outdoor structural applications.
US10300681B2 Intermediate film for laminated glass, method for producing intermediate film for laminated glass, and laminated glass
The present invention aims to provide an interlayer film for a laminated glass which enables production of a laminated glass with suppressed occurrence of optical distortion, a method for producing the interlayer film for a laminated glass, and a laminated glass produced using the interlayer film for a laminated glass. The present invention relates to an interlayer film for a laminated glass produced by an extrusion lip embossing method utilizing melt fracture, the interlayer film for a laminated glass including a laminate that includes two or more resin layers in a stack and having a large number of protrusions and recesses on at least one surface, a maximum height Ry (μm) and an average interval Sm (μm) of the protrusions and recesses measured in conformity with JIS B 0601 (1994) on the surface with protrusions and recesses satisfying a formula (1): (Ry×Sm)/2≤3,500  (1).
US10300677B2 Composite sheet and cargo container comprising same
A non-rigid composite sheet comprising in order (i) a first component comprising at least one first fabric of continuous filament yarns having a tenacity of at least 11 g/dtex and a first polymeric layer, (ii) a second component comprising at least one second fabric of continuous filament glass yarns, the at least one second fabric being adjacent to the at least one first fabric of the first component, and (iii) a third component comprising a second polymeric layer.
US10300675B2 Lightweight flexible thermal protection system for fire protection
A portable thermal protection system is provided for protecting equipment, facilities, and personnel in a region from a high intensity incident heat source. The system can be formed as a sleeping bag, a tent, a blanket, a sleeping bag, a vertical barrier, a curtain, a flexible rollup doorway, or a wrap. The system includes an outer textile layer first layer, an insulator second layer, and a non-porous film third layer which forms a gas barrier. Some embodiments include a fourth layer formed of a material to provide radiation protection. In some embodiments, the first and/or second layers are integrally formed with the materials that reflects radiation. The layers are joined together by high-temperature adhesives, stitching, needling, or tacking.
US10300674B2 Profile part with a plurality of layers
A profile part is disclosed. The profile part has a plurality of layers, each having a fiber reinforced plastic, where at least two layers differ in terms of at least one of the parameters characterizing the layers.
US10300673B2 Highly decorated tube, especially highly decorated laminate tube
A flexible tube skirt (10) has a primary film (20) and a decorative film (30), wherein the decorative film (30) has a decoration substrate and a sealable outer layer (33) The decoration substrate is applied on all of at least one of the surfaces of the primary film (20) and is below the sealable outer layer (33). The flexible tube skirt may be used in a flexible tube.
US10300671B2 Compaction receptacle
A compaction capable receptacle may include a housing with a trash receiving opening, a compaction unit arranged within the housing, and a trash bin arranged within the housing and articulable between a compaction position within the housing and a trash receiving position within the housing, the compaction position aligning the trash bin with a compaction stroke of the compaction unit and the trash receiving position aligning a portion of the trash bin with the trash receiving opening.
US10300669B2 Phase change composite bimorphs
A bilayer composite thin-film beam structure is described. The structure incorporates a bulk phase change material as small inclusions in one layer of a bimorph. The structure, also referred to as a “phase change composite bimorph” or “PCBM”, curls abruptly, and reversibly, at a phase transition temperature. Large curling and effective expansion coefficients are demonstrated. The PCBMs may be employed in various self-assembly mechanisms and actuators.
US10300664B2 Method and a device for the welding of two parts to be joined made of thermoplastic synthetic materials along a weld seam by means of laser
A system for welding two parts to be joined made of thermoplastic synthetic materials along a weld seam by a laser operating with a laser beam having a beam direction within an operating field by a control method with control data corresponding to the weld-seam course to be produced, including a beam dimension in the region around its focus causing the welding, which is smaller in the joint plane than the target width of the weld seam to be produced, and is dependent upon the angle of incidence of the laser beam on the joint plane and/or upon the position of the focus relative to the joint plane, is displaced in a first movement component in a principal forward-feed direction along the track of the weld-seam to be produced, in a second, oscillating movement component superimposed over the former to cover the weld-seam width transversely to the principal forward-feed direction with an oscillation amplitude value, and is adjusted with a control method in its oscillation amplitude width in inverse dependence upon the beam dimension in the joint plane such that the width of the beam field covered by the laser beam in the transverse direction relative to the principal forward-feed direction corresponds to the target width of the weld seam.
US10300663B2 Apparatus and method for forming three-dimensional objects using a tilting solidification substrate
An apparatus and method for making a three-dimensional object from a solidifiable material using a linear solidification device is shown and described. The apparatus includes a solidification substrate assembly that is tiltable about a tilting axis to peel a solidification substrate from a recently formed object surface and to level the solidification substrate assembly and squeeze out accumulated solidifiable material between the solidification substrate and the recently formed object surface. Intelligent peeling and leveling may also be provided by providing a tilting parameter database that is used to adjust tilting parameters based on object geometry and/or solidifiable material properties.
US10300661B2 Method and equipment for defining a supporting structure for a three-dimensional object to be made through stereolithography
The invention is a computer-implemented method for defining a supporting structure (2) for a three-dimensional object (1) to be produced through a stereolithography process, comprising the following operations: defining a first surface (3) to be supported of the three-dimensional object (1) and a second surface (4) facing the first surface (3); defining elongated supporting elements (5) between the surfaces (3, 4); defining pairs of supporting elements (5); for each pair of supporting elements (5), defining an elongated reinforcing element (6) connecting the two supporting elements (5) of the pair. The definition of the pairs of supporting elements (5) comprises the following operations: defining a reference point (7) of each supporting element (5); defining a connected acyclic graph (8) having as vertices the reference points (7); for each edge (9) of the graph, defining one pair of supporting elements comprising the two supporting elements (5) corresponding to the ends of the edge (9). The definition of the pairs of supporting elements (5) comprises the further operation of defining an additional pair of supporting elements for each vertex having order 1 of the connected acyclic graph (8), the additional pair comprising a first supporting element (5) corresponding to the vertex having order 1 and a second supporting element (5) not connected to the first supporting element (5) through any edge (9).
US10300658B2 Crack resistant plastic enclosure structures
Electronic device housing structures and other structures may be formed from molded plastic. Plastic structures such as injection molding housing structures and other structures may be provided with openings. An opening may have sidewall surfaces. Machining operations and other techniques may be used in forming the openings. Openings may be processed to enhance resistance to stress-induced cracking of the plastic structures along the sidewall surfaces. Cracking resistance may be obtained by activating the surface using heat or laser treatment and by electroplating the activated surface to form a metal liner structure. Surface treatments using applied liquid chemicals or heat may form a treated layer on the surface of an opening with enhanced cracking resistance. A plastic sleeve or other insert may form a liner structure in an opening that resists cracking. Liner structures may also be formed by applying heat or light to a coating in an opening.
US10300657B2 Corrosion inhibiting sprayable thermoplastic cover for mechanical assemblies, and methods of making and using
A Corrosion Inhibiting Sprayable Thermoplastic (“CIST”) cover is formed by spraying melted CIST onto a mold, allowing the CIST to cure, removing the cured cover from the mold using a series of cuts if necessary, positioning the cover on a mechanical assembly whose shape is significantly identical to the mold, and fusing the cuts on the cover using heat to reform the cover on the mechanical assembly.
US10300656B2 Testing apparatus used for cured sample liners used in rehabilitation of pipeline having sample liner exposed to pressure and UV light
A testing apparatus for onsite creation of cured sample liners necessary for confirming proper rehabilitation of pipelines includes a testing box having a base with a plurality of upstanding side walls defining an open upper end of the testing box. The testing box also includes an electrical power control assembly and an ultraviolet light assembly. A liner support manifold is shaped and dimensioned for supporting a sample liner and for attachment to the open upper end of the testing box for exposing the sample liner to pressure and ultraviolet light. In practice, and with the sample liner secured to the liner support manifold and the liner support manifold secured to the testing box, the sample liner is exposed to pressure and UV light in a highly controlled manner allowing for replication of actual in-line curing processing.
US10300655B2 Tool for fixing a textile sleeve about an elongate member to be protected and method of use thereof
A tool for fixing a protective textile sleeve about an elongate member contained therein and method of use thereof is provided. The tool includes a clamp assembly having opposed clamp members attached to one another for pivotal movement relative to one another between an open state and a closed state. The clamp members have clamping surfaces, wherein at least one of the clamping surfaces has at least one outlet. A fluid source is arranged in fluid communication with the at least one outlet, and a heat source is configured to heat fluid from the fluid source to create steam. The steam is dispensed outwardly from the at least one outlet to cause an adhesive on the sleeve to become activated to bond with an adjacent abutting surface.
US10300654B2 Methods of manufacturing sequentially stretched polymer films, apparatus used for such methods, and products obtained thereby
Methods include at least one sequential stretching step between circular or spiralized grooved rollers and the sequential stretching is performed according to at least one of six aspects of the invention.
US10300652B2 Method for fabricating containers
A method for fabricating containers wherein a molding apparatus is provided having a plurality of mold segments, each of which has two substantially opposite faces that form a mold cavity when abutted against an opposite face of an adjacent mold segment. A first mold segment is passed through a manipulation zone at an increased speed to open the mold cavity between the first and second mold segments. After a preform is positioned within the mold cavity, a second mold segment is passed through the manipulation zone at an increased speed to abut a face of the first mold segment against an opposite face of the second mold segment. A volume of a liquid is next injected into the preform, expanding the preform and forming the container. These steps are repeated and a container produced during the previous iteration is removed during an extracting step in an extracting manipulation zone.
US10300649B2 Enhancing die flatness
Methods and apparatus for enhancing the flatness of a die by applying adhesive to a shim having a selected flatness, rotating the shim to spread the adhesive to a layer having a uniform thickness, evacuating a chamber to create a vacuum; manipulating a die onto the adhesive layer in the chamber; and reducing a level of the vacuum to pressure the die onto the adhesive layer such that the bow in the die is reduced as the die conforms to the shim.
US10300645B2 Injection device and axial-center position adjusting method
An injection device includes a spline supporting member rotatably supporting a spline shaft and attached to a pressure plate, and a nut supporting member rotatably supporting a spline nut and attached to a rear plate. The spline supporting member is provided with a spline positioning mechanism for adjusting the mounting position of the spline supporting member. The nut supporting member is provided with a nut positioning mechanism for adjusting the mounting position of the nut supporting member. The spline supporting member and the nut supporting member are formed with holes for axial-center checking, rods being inserted through the holes.
US10300643B2 Manufacture method of liquid supply member and manufacture apparatus
First and second constituting components are injection-molded and joined within one pair of molds. In order to join the first and second constituting components, one of the respective regions of the first and second constituting components abutted to each other is pushed into the other.
US10300639B2 Imprint method, and imprint apparatus for implementing the same
An imprint method includes, in the peeling step of peeling a mold off the material layer to be transferred, a region-of-contact recognition operation of recognizing and determining a region of contact of the mold with the material layer to be transferred, a center-of-gravity locating operation of determining a center of gravity of a morphology of the thus recognized region of contact on the basis of that morphology, and a peeling operation of determining a point of force for applying peeling force to the mold or the imprinting substrate in relation to the center of gravity determined by the center-of-gravity locating operation, thereby acting the peeling force on the point of force.
US10300632B2 Method of producing preform
A method of producing a preform, having a step for preparing a sheet-shaped prepreg and a preform mold having a forming surface and a separable portion constituting at least a portion of the forming surface, forming the prepreg using the preform mold, and then removing the preform together with the separable portion from the preform mold.
US10300631B2 Carbon fiber preforms
In some examples, a method including depositing a resin and a plurality of carbon fibers via a print head of a three-dimensional printing system to form a carbon fiber preform including a plurality of individual carbon fiber layers, wherein each individual layer of the plurality of individual carbon fiber layers includes the resin and carbon fibers, and wherein the carbon fiber preform exhibits at least one of a non-uniform composition of the resin within the preform, different types of the carbon fibers within the preform, or non-uniform fiber orientation within the preform.
US10300629B2 Method for controlling a wall saw system when making a separating cut
A method for controlling a wall system when creating a separating cut in a workpiece between a first and a second end point is disclosed. The wall saw system includes a wall saw having a saw head, a pivotable saw arm, a saw blade and a blade guard. The separating cut is carried out in a plurality of main cuts. The pivoting movement of the saw arm in a main cutting angle is carried out in at least two steps with at least one intermediate angle, where a free cut of the saw blade is carried out in the respective intermediate angle between the pivoting movements of the saw arm.
US10300628B2 Tool and machine for working natural stone, agglomerate or ceramic material
A machine (12) for working slabs of natural stone, agglomerate or ceramic material comprises: a work bench (14) adapted to receive a slab to be machined; a machining head (16) comprising a spindle (18); and movement means (20) for moving the machining head (16) above the work bench (14). The spindle (18) comprises coupling means (40) which allow a diamond chain tool (42) to be operatively fixed.
US10300621B2 Method for producing cut bodies and method for cutting fiber-reinforced resin
According to an aspect of the present invention, there is provided a method for producing cut bodies including: cutting a fiber-reinforced resin material, the fiber-reinforced resin material including reinforcing fibers and a thermoplastic resin, the reinforcing fibers having a tensile strength of 1,000 MPa to 6,000 MPa; and heating the fiber-reinforced resin material, wherein a flexural modulus of the fiber-reinforced resin material at the cutting is decreased to a value ranging from 80% to 15% of the flexural modulus of the fiber-reinforced resin material before heating.
US10300620B2 Ground anchor strap puller, tensioner and cutter
A tool for advancing and tensioning a strap of an erosion control system through an aperture of a retaining washer to provide hold down pressure to an erosion control mat is described. The tool has a foot member that is positioned atop the retaining washer and serves to hold it in place during the installation operation. An upright support bar extends above the foot member and a slide tensioning subassembly is mounted for sliding movement on the support bar. A clamp is carried on the slide tensioning subassembly for releasably grasping the strap. A handle is mounted on the upright support bar for up and down sliding movement and interconnected to the slide tensioning subassembly and the clamp so that downward movement of the handle closes the clamp to grasp the strap and pull the slide member upwardly to advance the strap through the washer.
US10300617B2 Cutting tool and manufacturing method
A cutting tool includes first and second blades attached to each other by a joint, and first and second handles. A first inlay having a protruding end protrudes into a hole in the first blade. A shaft has a first end joined to the protruding end of the first inlay, and has a second end with at least one transverse shoulder. A second inlay has a protruding end protruding into a hole in the second blade and a hole receives the second end of the shaft, and an engaging surface engages with the shoulder of the shaft. The hole of the second inlay has a shape and width allowing the second end of the shaft with the shoulder to pass into the hole in a release position, but prevents the shaft and shoulder from passing through the hole when the shaft and second inlay are not in the release position.
US10300611B2 End effector assembly and method of operation to grasp non-planar articles
An end effector is configured to grasp articles that have deviated from their original shape. The end effector can return the article to its expected condition. The end effector can include a main platform, a first sub-platform and a second sub-platform. A first suction cup extends vertically below the main platform. Each of the sub-platforms includes one or more suction cups, respectively, that protrude vertically below the sub-platforms. Each sub-platform is connected to the main platform via a bellows actuator that can be extended and retracted via positive and negative pressures. The main platform can include fittings to allow the end effector to be attached to a wide variety of robotic arms, such as a delta robot.
US10300610B1 High density container gripping system and method
A system and method for automated palletization of totes and cuboid containers includes an end effector having fingers projecting outwardly. The fingers may engage recesses in the totes. Alternatively, actuators on fixed fingers can move gripping surfaces into engagement with the totes or containers. Or actuators on a body of the end effector can move the fingers, which include gripping surfaces.
US10300609B2 Motor and controller integration for a legged robot
An example robot includes: a motor disposed within a housing at a joint configured to control motion of a member of a robot; a controller including one or more printed circuit boards (PCBs) disposed within the housing and including a plurality of field-effect transistors (FETs) disposed on a surface of a PCB of the one or more PCBs facing the motor; a rotary position sensor mounted on the controller; a shaft coupled to a rotor of the motor and extending therefrom to the controller; and a magnet mounted within the shaft at an end of the shaft facing the controller.
US10300606B2 Adapting robot behavior based upon human-robot interaction
Technologies pertaining to human-robot interaction are described herein. The robot includes a computer-readable memory that comprises a model that, with respect to successful completions of a task, is fit to observed data, where at least some of such observed data pertains to a condition that is controllable by the robot, such as position of the robot or distance between the robot and a human. A task that is desirably performed by the robot is to cause the human to engage with the robot. The model is updated while the robot is online, such that behavior of the robot adapts over time to increase the likelihood that the robot will successfully complete the task.
US10300603B2 Methods and apparatus for early sensory integration and robust acquisition of real world knowledge
The systems and methods disclosed herein include a path integration system that calculates optic flow, infers angular velocity from the flow field, and incorporates this velocity estimate into heading calculations. The resulting system fuses heading estimates from accelerometers, gyroscopes, engine torques, and optic flow to determine self-localization. The system also includes a motivational system that implements a reward drive, both positive and negative, into the system. In some implementations, the drives can include: a) a curiosity drive that encourages exploration of new areas, b) a resource drive that attracts the agent towards the recharging base when the battery is low, and c) a mineral reward drive that attracts the agent towards previously explored scientific targets.
US10300602B2 Method and means for handling an object
A method for handling an object comprises the steps: a) connecting the object (1) with a manipulator (5) and with an input tool (7) by means of which a direction ({right arrow over (d)}′) within an internal coordinate system (K′) relating to the input tool (7) can be entered, d) initiating a test movement of the manipulator (5) on the basis of a direction ({right arrow over (r)}) known in the external coordinate system (K); e) determining the direction ({right arrow over (r)}′) of a movement of the input tool (7) in the internal coordinate system (K′) resulting from the test movement of the manipulator (5); f) determining a coordinate transformation (T) which transforms the direction of the resulting movement ({right arrow over (r)}′) in the internal coordinate system into the known direction ({right arrow over (r)}) in the external coordinate system; g) detecting an internal direction ({right arrow over (d)}′) within the internal coordinate system (K′) entered by a user using the input tool (7); h) applying the coordinate transformation (T) to the detected internal direction ({right arrow over (d)}′) in order to obtain an external direction ({right arrow over (d)}); and i) controlling a movement of the manipulator (5) on the basis of the external direction ({right arrow over (d)}).
US10300601B2 Vehicle control system with task manager
A locomotive control system may include first and second robotic machines and a task manager. The first and second robotic machines have respective first and second sets of capabilities for interacting with a surrounding environment. The task manager selects the first and second robotic machines from a group to perform a task based on the first and second sets of capabilities of the robotic machines. The task involves manipulating and/or inspecting a target object of a vehicle. The task manager assigns a first sequence of sub-tasks to be performed by the first robotic machine and a second sequence of sub-tasks to be performed by the second robotic machine. The first and second robotic machines are configured to coordinate performance of the first sequence of sub-tasks by the first robotic machine with performance of the second sequence of sub-tasks by the second robotic machine to accomplish the task.
US10300597B2 Robot and method of operating robot
A robot includes a base, a body connected to the base, a pair of articulated arms rotatably connected to the body, and a moving mechanism adapted to move the body toward or away from the base. Further, a relative positional relationship with a workbench is detected by moving the body with respect to the base using the moving mechanism while keeping the articulated arms in predetermined postures while facing the workbench, and then making the articulated arms contact the workbench.
US10300588B2 Method of setting a drop-in anchor
The present invention relates in general to the field of securing structural members to masonry, and more specifically, to a drop-in anchor setting tool and method of use. The drop-in anchor setting tool includes a hands-free safety feature that allows the drop-in anchor and setting tool to remain embedded in the masonry during installation. In particular, the drop-in anchor setting tool includes a threaded portion configured to screw together the drop-in anchor and the drop-in anchor setting tool during installation. A purpose of invention is to provide a drop-in anchor setting tool and method of use that minimizes risk of injury to the operator during installation, is easy to use, and cost-effective to manufacture.
US10300587B2 Clip installation tool
Tools for installing a clip having a depressible engagement member are disclosed. In one embodiment, the tool includes a pin and a head both configured to engage the depressible engagement member. A trigger assembly is mechanically coupled to both the pin and the head. The pin is configured to actuate the trigger assembly so as to release the hear, wherein the head may actuate a counting unit so as to register a count when the pin engages the depressible engagement member, informing the installer when a clip is properly installed.
US10300585B2 Ratchet type power wrench
A ratchet type power wrench includes a housing, a pressure medium powered actuator, a ratchet mechanism included in the housing and coupled to the actuator, an open ended output socket with a constant cross sectional dimension throughout a length thereof, which is rotatably supported in the housing and engaged by the ratchet mechanism, and an angle encoder provided to indicate angular displacements of the output socket. The angle encoder has a form of a separate unit included in a casing, the casing being attachable to either side of the housing for connecting the angle encoder to either end of the output socket. The angle encoder includes a rotatable signal initiating part and a movement sensor rigidly mounted in the casing, the rotatable signal initiating part being provided with at least one coupling dog adapted to engage cavities located at both ends of the output socket.
US10300581B2 Methods of making abrasive articles and bonded abrasive wheel preparable thereby
Methods of making abrasive articles involve adhering shaped abrasive particles to a reinforcing member according to a predetermined pattern and optionally orientation, and depositing a space-filling binder precursor on the reinforcing member and shaped abrasive particles to provide a filled abrasive preform, disposing another reinforcing member onto the filled abrasive preform, and curing the abrasive article precursor to form the abrasive articles. In some aspects, multiple abrasive preforms are stacked on each other. Bonded abrasive wheels preparable according to the methods are also disclosed.
US10300579B2 Grinding coolant supplier, grinding system and grinding method
A grinding coolant supplier configured to supply a grinding coolant to a grinder configured to grind an element of a machine part having a rolling element, the grinding coolant supplier including: a grinding coolant generation apparatus configured to generate a grinding coolant which is a mixture of a water-soluble stock coolant, a first reformed water of which water particles have an average particle size of not smaller than 80 nm and not greater than 150 nm, and a second reformed water of which water particles have an average particle size of not smaller than 5 nm and smaller than 80 nm; and grinding coolant supplying device configured to supply the generated grinding coolant to the grinder.
US10300573B2 Measurement, layout, marking, firestop stick
Multiple cameras are used for tool positioning, as-built documentation, and/or personnel monitoring in construction site. A camera unit comprises one or more imaging devices, a processing computer, and a communication device. The camera units are placed at multiple locations in a construction site to cover an area. The camera units are self-positioned by detecting a calibration target that moves within a working volume. The camera units can detect and calculate positions of objects, including measurement sticks, tools, personnel, etc., in the area.
US10300569B2 Method for fabricating vacuum fixturing using granular media
A method for fabricating vacuum tooling is disclosed using porous granular media. A sheet of steel webbing is affixed to a frame. A plurality of layers of fiberglass is affixed to the webbing. A vacuum port is installed through the webbing and plurality of layers of fiberglass. A granular media is mixed with epoxy to form a granular mixture. The granular mixture is layered over the plurality of layers of fiberglass to form a flat surface and machined for uniformity before sealing.
US10300568B2 Compensating face plate vise jaws and related methods
Disclosed generally is a face plate for a vise that is capable of gripping multiple work-pieces of different sizes at the same time. In one embodiment, the disclosed subject matter may be a vise face plate comprising: a base with an upper compensation structure and a lower compensation structure; and, wherein the upper and lower compensation structures define two sets of working surfaces. In use, the plate may be secured to a movable jaw so that the working surfaces may be employed to clamp a plurality of work pieces between the working surfaces and a fixed jaw.
US10300566B2 Method and apparatus for precision alignment and tack welding of weld-neck pipe fittings to pipe
Internal clamping of a weld-neck fitting to a pipe in preparation for precision tack welding of the fitting to the pipe is established by a pair of alignment and clamping wedge members, each having alignment and gripping members and angulated reaction surfaces which are positioned within the pipe and weld-neck fitting with the angulated reaction surfaces in relatively moveable engagement. One of the alignment and clamping wedge members is moved linearly, causing the angulated reaction surfaces to translate the linear movement to lateral movement, forcing the alignment and gripping members laterally against the internal surfaces of the pipe and fitting and supporting the fitting in precision aligned relation with the pipe to facilitate tack welding. A gauge member confirms precision alignment of the fitting with the pipe before and after applying the tack welds, then the alignment and clamping apparatus is loosened by opposite linear movement of the wedge members which are removed to permit final weld connection of the fitting to the pipe.
US10300565B2 Systems and methods for welding mill scaled workpieces
This disclosure relates generally to Gas Metal Arc Welding (GMAW) and, more specifically, to Metal-cored Arc Welding (MCAW) of mill scaled steel workpieces. A metal-cored welding wire, including a sheath and a core, capable of welding mill scaled workpieces without prior descaling is disclosed. The metal-cored welding wire has a sulfur source that occupies between approximately 0.04% and approximately 0.18% of the weight of the metal-cored welding wire, and has a cellulose source that occupies between approximately 0.09% and approximately 0.54% of the weight of the metal-cored welding wire.
US10300559B2 Laser drilling method and apparatus with radiation output changes in a radial direction during drilling of a workpiece
A laser drilling method is a laser drilling method for performing drilling on a workpiece by use of a laser beam. The laser drilling method includes, after machining a through hole by radiating the laser beam to the workpiece (S100), scanning with the laser beam centered around the through hole toward a radial direction while changing a radiation output of the laser beam (S200).
US10300557B2 Hybrid substrate processing
A hybrid laser modulation and acid etch process for the creation of a patterned substrate. According to some embodiments, a hole is formed in a glass substrate by first modulating a portion of the substrate in the desired shape. A mask is coated on the glass substrate and is patterned to expose the modulated portion. The glass substrate is then acid etched to remove the modulated portion. Once the modulated portion has been etched, the desired shape may be removed from the glass substrate and the mask may be stripped.
US10300556B2 Controller with drop prevention function for gap control axis
A controller performs gap control such that a Z-axis position of a tip of a cutting head of the machine is not below a preset lower limit position while keeping the distance between the tip of the cutting head and a workpiece constant. The numerical controller calculates a substantial lower limit position based on a detected state of the workpiece and the preset lower limit position. If the Z-axis position of the tip of the cutting head is below the calculated substantial lower limit position, it is compensated so as not to be below the substantial lower limit position.
US10300555B2 Laser cutting machine and method for cutting workpieces of different thicknesses
A laser cutting machine for cutting a workpiece having a first thickness (using a first processing laser beam having a first laser beam characteristic and a workpiece having a different second thickness using at least a second processing laser beam having a different second laser beam characteristic includes a laser source for producing a unprocessed laser beam having a laser wavelength of less than 4 μm, a device which forms from the unprocessed laser beam the processing laser beams, and a control unit which controls the device in dependence on the thickness of the workpiece to be cut.
US10300554B2 Wafer alignment method and system
Wafers are aligned with one another by reference to features formed on or in each wafer. Notches are formed in each wafer, including a pivot-notch that allows for two-point contact, and a stop-notch that provides for single-point contact. A bias-notch is formed for pressing the wafers into engagement with the two-contact element when it is in the pivot-notch and with the single-contact element when it is in the stop-notch. The wafers may be bonded to one another to maintain the alignment of the referenced features.
US10300549B2 Intelligent waveform selection for a welding system having particular electrical output characteristics
Systems and methods for selecting a welding output waveform based on characterizing a welding circuit output path with respect to its electrical characteristics. At least one electrical characteristic (e.g., inductance, resistance) of a welding output circuit path connected to a welding power source is determined. A welding output waveform is selected from a plurality of welding output waveforms based on the determined electrical characteristics. As a result, the selected welding output waveform is matched to the welding output circuit path electrical characteristics to provide superior welding performance.
US10300546B2 Spherical articulating fixture
A fixture includes a base with a bottom and a rim, a clamp with an exterior in a shape of a portion of a clamp sphere and a component space that is wholly within the clamp sphere, wherein the clamp is positioned such that the clamp exterior is in contact with the rim.
US10300542B2 Wire electrical discharge machining apparatus and method of manufacturing semiconductor wafer
A controller controls cutting of simultaneously cutting wafers by performing electrical discharge machining while moving a workpiece relative to cutting wire sections in a direction at right angles to the cutting wire sections in a plane perpendicular to the axial direction of main guide rollers and leaving a connection at which a part of each wafer that has been incompletely cut is still connected to the workpiece, and shape correction of causing the cutting wire sections to perform scanning while performing electrical discharge machining along a path of the cutting wire sections in a cutting direction at the time of the cutting to simultaneously correct the shape of a plurality of cut surfaces that are cut at the time of the cutting.
US10300539B2 Rotating-cutting-edge-type milling tool and cutting method using same
A virtual plane obtained by a locus when a tangent line, which passes through a tool distal end edge, of a virtual circle formed when a tool distal end edge of a cutting edge is rotated in a tool circumferential direction is moved parallel to a tool axial line is a reference plane, an angle (ARt) at which a cross line of the reference plane and the cutting edge virtual plane, is inclined with respect to the tool axial line projected onto the reference plane, is in a range of −30 degrees to −60 degrees, an angle (RR) at which a cutting edge tangent line which passes through the tool distal end edge and extends outward in a tool radial direction, is inclined with respect to a predetermined tool radial direction, which passes through the tool distal end edge, is in a range of −30 degrees to −75 degrees.
US10300538B2 Milling insert
A milling insert, including an upperside, an underside, and a reference plane parallel thereto. A plurality of indexable cutting edges are formed along a peripheral borderline in transitions between at least the upperside and a number of clearance surfaces. Each cutting edge includes a chip-removing main edge and a surface-wiping secondary edge. The main edge, from a first end of the main edge adjacent to the secondary edge, first declines toward the underside of the milling insert and then, from a lowest part, rises toward an opposite second end of the main edge. The secondary edge is inclined at an angle (ε) in relation to the reference plane as viewed perpendicularly to the clearance surface of the secondary edge, such that a first end of the secondary edge connected to the main edge is situated on a lower level than the opposite, second end of the secondary edge.
US10300533B2 Coated cutting tool
A coated cutting tool has a substrate and a coating layer formed onto a surface of the substrate. The coating layer contains a hard layer of a composition represented by (TixM1-x)N, wherein M represents at least one kind of an element selected from the group consisting of Zr, Hf, V, Nb, Ta, Cr, Mo, W, Al, Si and Y, and x represents an atomic ratio of a Ti element based on a sum of the Ti element and an M element, and satisfies 0.45≤x≤0.9. Also, an average grain size of grains constituting the hard layer is 200 nm or more and 600 nm or less, and the grains of the hard layer satisfy predetermined conditions.
US10300531B2 Methods of manufacturing composite materials, composite wires, and welding electrodes
The present disclosure provides a method of manufacturing a composite material. The method can include compacting a copper alloy powder into a plurality of substantially uniform compressed sub-assemblies such that the copper alloy powder has a density that is greater than 50%. The plurality of compressed sub-assemblies can be layered relative one another within an aperture of a shell, the plurality of compressed sub-assemblies to form a consecutive assembly of compacted copper alloy. The shell may include one of the following: a precipitation hardened copper alloy, copper alloy, and carbon steel. The consecutive assembly can be sealed within the shell to form a billet. The billet can be hot-extruded to form a rod, and the extruded rod can be further drawn to form a composite wire of a desired diameter. The composite wire may be used to create a composite welding electrode.
US10300528B2 Ingot loading mechanism for injection molding machine
Disclosed is an apparatus for loading one or more alloy ingots into a molding machine. The apparatus includes a holder configured to hold a plurality of the alloy ingots and dispense one or more of the alloy ingots into a melt zone of the molding machine through an opening in a mold of the machine. The holder is moved in a perpendicular direction with respect to an axis along a center of the opening in the mold between a first position in line with the opening in the mold to dispense one or more of the alloy ingots and a second position away from the opening in the mold. The apparatus can carry ingots of amorphous alloy material so that when the machine melts and molds the material, it forms a bulk amorphous alloy containing part.
US10300525B2 Molten metal filtration device
This filtration device 10 has a can body 20 having a reservoir 3 that connects to an opening 9 at the top, and a filtration unit 40 which is detachably installed in the reservoir. The filtration unit has a support plate 42, and filtration tubes 41 of bottomed cylindrical shape fastened to the support plate. The side wall 22 of the can body 20 has a protruding locking part 30 for installation of the filtration unit so that the filtration tubes are suspended from the support plate 42, with the openings 43 thereof facing upward. With the support plate 42 locked into the locking part 30, pressing members 70 for pressing the support plate 42 downward from the upper surface side in sections thereof lying towards the peripheral edge S in relation to the fastening locations of the filtration tubes 41 are deployed, making it possible for the support plate 42 to be fastened in clamped fashion by the locking part 30 and the pressing members 70.
US10300521B2 Method and apparatus for curling an article
An apparatus for forming a curl on an article includes a first forming tooling having a first set of rollers mounted on a common head. The first set of rollers has a respective groove having a first groove radius. The apparatus further includes a first rotating turret configured to load the article into the first forming tooling. The apparatus further includes a second forming tooling having a second set of rollers mounted on a common head. The second set of rollers has a respective groove having a second groove radius. The second groove radius is larger than the first groove radius. The apparatus further includes a second rotating turret configured to load the article into the second forming tooling. The apparatus further includes a first transfer star wheel configured to transfer the article from the first rotating turret to the second rotating turret.
US10300517B2 Pipe end straightener
A method and apparatus for straightening a casing is provided herein. The method can include securing a casing in a pipe end straightener, where the pipe end straightener includes a mounting platform, an analog feedback device, and a hydraulic press. The method can also include measuring one or more characteristics of a bent portion of the casing with the analog feedback device. The method can also include straightening the casing by applying a calculated force to the casing with the hydraulic press.
US10300516B2 Process for producing a multilayer pipe by expansion and multilayer pipe produced by said process
A process for producing a multilayer pipe by expansion is disclosed, with or without heating, in which a multilayer pipe (1) comprises at least one outer pipe of metallic material (10) and an inner pipe of metallic material (20), the inner pipe of metallic material (20) having a yield strength lower than the yield strength of the outer pipe (23) and an external diameter smaller than the internal diameter of the outer pipe. The process for producing the multilayer pipe comprises a mounting step (34) between the pipes (10, 20), wherein the inner pipe is inserted inside the outer pipe, and at least one mechanical expansion step (36), comprising moving a mandrel (2) longitudinally and internally in the inner pipe (20) while the outer pipe and the inner pipe are held at a fixed position, wherein at least part of the mandrel (2) has a greater external diameter than the internal diameter of the inner pipe. When the pipes are subjected to a process of cold expansion, a “lined pipe” is obtained, which is characterized by mechanical bonding between the pipes. When the pipes are subjected to a process of hot expansion, a “clad pipe” is obtained, which is characterized by metallurgical bonding between the pipes.
US10300513B2 Piercing plug and manufacturing method of piercing plug
A piercing plug includes a plug main body, and a sprayed coating which is formed on a surface of the plug main body and includes iron and iron oxide. A chemical composition of the sprayed coating includes, in addition to the iron and the iron oxide, by mass %, C: 0.015% to 0.6%, Si: 0.05% to 0.5%, Mn: 0.1% to 1.0%, and Cu: 0 to 0.3%.
US10300509B2 Method and system for delivery of goods based on a virtual address
The present publication discloses a method and system for delivering goods from main system (S1) via subsystem (S2) to an end address (D1-Dn) of the customer (3). According to the invention the end address (D1-Dn) of the customer (3) is enquired (4) from the customer via telecommunications network by a multiple choice enquiry (4), the end address (D1-Dn) selected by the customer is received (5) and the goods are delivered to the selected end address (D1-Dn).
US10300508B2 Trommel screen with different sized apertures
A screening machine includes a rotary trommel screen having an overall length. The rotary trommel screen has an inlet and an outlet end. The screening machine includes a first collection area proximate to the inlet end and under the rotary trommel screen. The first collection area corresponds to at least 65 percent of the overall length of the trommel screen. The screening machine includes a second collection area proximate to the outlet end and under the rotary trommel screen. The second collection area corresponds to the remainder of the overall length of the trommel screen not corresponding to the first collection area. The first and second collection areas are configured to separate a first and second product respectively. Sections of the trommel screen corresponding to the first and second collection areas are configured such that a size of the first product is different than a size of the second product.
US10300506B2 Dispensing apparatus, dispensing system and method of dispensing
A dispensing apparatus includes a body, two inlets for flowable masses and two outlets through which the flowable masses can be dispensed, with one inlet being connected to one outlet and the other inlet being connected to the other outlet through the body. The two inlets are spaced apart from one another by a first spacing and the two outlets are spaced apart from one another by a second spacing, and with the second spacing being larger than the first spacing. A connection ring engages the body and is pre-mounted to the body. The dispensing apparatus is configured to be non-releasably connected to a two-component cartridge via the connection ring for the supply of the flowable masses to the inlets.
US10300499B2 Centrifuge with removable rotor
A centrifuge having a driveshaft that has an end section that tapers toward the central axis of the driveshaft. A rotor is removably mounted on the driveshaft such that the rotor may be axially removed in a removal direction. A bearing surface of a locking element of the rotor is connected to the driveshaft and holds the rotor against removal. A quick-action closure is integrated into the rotor and prevents removal of the driveshaft and the rotor in the removal direction. The end section of the driveshaft extends through an opening in the rotor where it is partially surrounded by multiple locking elements of the rotor for fixing the rotor and the driveshaft together. The locking elements include bearing surfaces engaging the end section and support surfaces engaging the rotor. The quick-action closure has force-transmitting elements which connect the locking elements to a handle permitting locking and/or unlocking the quick-action closure by a respective movement of the handle.
US10300496B2 Silicon comprising polymer coated particles
The present invention relates to core-shell-particles, wherein the core comprises at least one metal, or a compound thereof, or a mixture of at least one metal or a compound thereof and at least one semimetal or a compound thereof, and the shell comprises at least one silicon comprising polymer, to a process for the preparation of these core-shell-particles, to the use of these core-shell-particles in an agglomeration-deagglomeration process, in particular in chemical, physical or biological test methods or separation processes, decontamination processes, water purification, recycling of electrical/electronic scrap or gravity separation, and to a process for separating at least one first material from a mixture comprising this at least one first material and at least one second material.
US10300494B1 Method of plant resin separation and extraction
A process for trichome separation from plant matter deploys water slurry agitation and/or dry sieving to produce a mixture of solid trichomes and similar sized plant debris. The plant debris in each separate fraction is then removed by gravity filtration in a dense inert liquid, which is preferably a salt or brine solution. The desirable trichomes or trichome glands float on the dense liquid, while the undesirable vegetative matter sinks to the bottom of the brine containing vessel. The trichomes are readily removed and washed before further processing.
US10300493B2 Shell plate, method for making a shell plate and a grinding mill
The invention relates to a shell plate, to a method for making a shell plate and to a grinding mill for ore grinding. The shell plate is mountable to a shell of a grinding mill for grinding ore and includes a shell plate body having a first portion including a fixing surface for fixing the shell plate body to the shell, and a second portion having a wear surface facing toward an interior of the grinding mill. The first portion and the second portion form a continuous shell plate body, and the second portion includes polyurethane such that the wear surface is made of polyurethane.
US10300490B2 Rotary mill
A rotary mill for grinding recycled glass materials into particles has a housing defining an impact chamber with a rotor in the chamber at the bottom of an inclined guide wall underneath the feed opening. The rotor has a plurality of axially extending, angularly spaced massive impact hammers so that the impact hammers impact and deflect the solid materials onto a plurality of shatter bars located at the peripheral wall. Each of the impact hammers has a leading blade element of a hardened steel which has a front face inclined relative to a bottom portion of the guide surface so that an outer edge of the front face is angularly advanced relative to an inner edge thereof.
US10300487B2 Pipette holder
A holder for a pipette having a bulb is disclosed. In use, the bulb of the pipette is inserted into the holder and the user can hold the holder rather than the bulb to use the pipette. In this way, the holder enables the pipette to be held without any application of force from the user directly on the bulb. This enables the user to accurately draw a desired amount of liquid into the pipette. The holder comprises an aperture through which the bulb is accessible. The user can dispense liquid from the pipette by actuating the bulb through the aperture.
US10300478B2 Bipolar ion exchange sheet and manufacturing method therefor
The present invention relates to a bipolar ion exchange sheet and a manufacturing method therefor, the bipolar ion exchange sheet comprising: a cation exchange film comprising a cation adsorption sheet and a cation exchange coating layer formed on one side of the cation adsorption sheet; and an anion exchange film comprising an anion adsorption sheet and an anion exchange coating layer formed on one side of the anion adsorption sheet, wherein the cation exchange film and the anion exchange film are bonded so that the cation exchange coating layer and the anion exchange coating layer face each other.
US10300475B2 Circumferential coating material and circumferential coating honeycomb structure
A circumferential coating material which is coated on a circumferential surface of a honeycomb structure monolithically formed by extrusion, to form a circumferential coating layer, the circumferential coating material containing fused silica in a range of 20 to 75 mass %, containing a color developing agent in a range of 5 to 50 mass %, containing colloidal silica in a range of 5 to 30 mass %, and further containing a silicon based water repellent agent in a range of 1 to 10 mass % to a total mass of the fused silica, the color developing agent, and the colloidal silica.
US10300473B2 Catalytic composition comprising nickel and a ligand of the phosphane complexed with nickel type, and use thereof in a olefin oligomerisation method
The invention concerns a catalytic composition comprising: at least one nickel precursor with an oxidation number of (+II) containing a phosphine ligand complexed with nickel, at least one Lewis base, and at least one activating agent selected from the group formed by chlorinated and brominated hydrocarbylaluminium compounds, used alone or as a mixture, in a manner such that the molar ratio of the ensemble of the Lewis base and phosphine ligand complexed with the nickel of the composition to the nickel is in the range 5 to 30. The invention also concerns the use of said catalytic composition.
US10300471B2 Ruthenium-catalyzed synthesis of biaryl compounds in water
Using a [RuCl2(arene)]2 complex and a formate source, a directed ortho C—H insertion and aryl-aryl coupling sequence in water provides biaryl compounds useful in the preparation of biologically active molecules and intermediates. Reactions may be conducted in the ambient atmosphere. Ruthenium catalysts prepared from [RuCl2(arene)]2 and a formate source may be prepared in situ or isolated for later use.
US10300468B2 Process for the preparation of an MWW zeolitic material comprising boron and titanium
A process for the preparation of a zeolitic material having an MWW framework structure and comprising boron and titanium, the process comprising (i) providing an aqueous synthesis mixture comprising a silica source, a boron source, a titanium source, and an MWW templating agent; (ii) heating the aqueous synthesis mixture to a temperature in the range of from 160 to 190 ° C.; (iii) subjecting the synthesis mixture (ii) to hydrothermal synthesis conditions, obtaining, in its mother liquor, a precursor of the zeolitic material; (iv) separating the precursor from its mother liquor; (v) calcining the separated precursor, obtaining the zeolitic material having an MWW framework structure and comprising boron and titanium.
US10300463B2 Catalyst for manufacturing unsaturated aldehyde and/or unsaturated carboxylic acid and manufacturing method of same, and manufacturing method of unsaturated aldehyde and/or unsaturated carboxylic acid
Provided is a catalyst for manufacturing an unsaturated aldehyde and/or an unsaturated carboxylic acid, which is prepared by a method in which a molybdenum component raw material is composed of only an ammonium molybdate, the weight of water for dissolution is 8.5 times or less relative to the weight of molybdenum contained in the ammonium molybdate; and a bismuth component raw material is composed of only bismuth nitrate, the weight of a nitric acid aqueous solution for dissolution is 2.3 times or more relative to the weight of bismuth contained in the bismuth nitrate, and a nitric acid concentration in the nitric acid aqueous solution for dissolving the bismuth nitrate is 10% by weight or more.
US10300461B2 Catalytic converter
In order to specify a catalytic converter, especially SCR catalytic converter, with maximum catalytic activity, this catalytic converter has at least one catalytically active component and additionally at least one porous inorganic filler component having meso- or macroporosity. The organic porous filler component has a proportion of about 5 to 50% by weight. More particularly, a diatomaceous earth or a pillared clay material is used as the porous inorganic filler component.
US10300460B1 Aqueous methods for titanating a chromium/silica catalyst
Methods for synthesizing a water-soluble titanium-silicon complex are disclosed herein. The titanium-silicon complex can be utilized to produce titanated solid oxide supports and titanated chromium supported catalysts. The titanated chromium supported catalysts subsequently can be used to polymerize olefins to produce, for example, ethylene based homopolymer and copolymers.
US10300457B2 Fibers of variable wettability and materials containing the fibers
The present invention is directed to an absorbent material and the fibers therein, having two or more layers including an upper surface layer which has on the outer surface of the layer one or more surface area zones which are more wettable zones and adjacent thereto one or more less wettable zones, where the more wettable zones have a greater hydrophilicity than the less wettable zone. The present invention is also directed to the fibers therein, which contain polyvalent cation-containing compounds and fatty acid containing compounds. The present invention also provides for methods of treating fibers or solid materials and processes of producing the hydrophobic materials.
US10300454B2 Sulfur production
A system includes a first chamber, a second chamber, an ultraviolet light source and a microwave source. The first chamber includes an inlet. The second chamber is adjacent the first chamber and includes an outlet and a waveguide. The ultraviolet light source resides within the waveguide of the second chamber. Related apparatus, systems, techniques and articles are also described.
US10300453B2 Thin layer sonochemistry and sonoelectrochemistry devices and methods
A device which can increase the rates of interfacial reactions including heterogeneous electron transfer reactions, the device comprising at least one sono(electro)chemical cell adapted to hold a thin layer of condensed fluid which is optionally adapted to participate in a heterogeneous electron transfer reaction, wherein the cell is further adapted to provide an ultrasonic transducer face to propagate sound waves into the thin layer of condensed fluid, and wherein the cell is still further adapted with an opening to provide the thin layer of condensed fluid with at least one interface which provides for reflection of the sound waves from the interface back into the thin layer of condensed fluid. The cells are configured to provide for a thin layer operation as opposed to a bulk operation. In method embodiments, ultrasound is applied to the thin layer of condensed fluid. The application of ultrasound is carried out both without cooling of the cell and without pressurization of the cell. Methods of using the device include fuel cells and fuel cell electrodes. Systems having anodes and cathodes are also provided.
US10300451B2 Method for generating an affinity reagent library
The present disclosure provides a method for generating an affinity reagent library against a target protein which interacts with a ligand, which comprises the following steps; •i) determining one or more structural element(s) of the ligand which are involved in ligand: target protein interaction; •ii) producing a library of peptides which retain these structural element(s); and •iii) grafting each peptide from the library of peptides into a portion of the affinity reagent molecule such that it may interact with the target protein, in order to produce an affinity reagent library.
US10300450B2 Method and device for depositing a substance on a submerged surface
The present disclosure provides apparatuses, systems, and methods involving a spotter for depositing a substance on a submerged surface. The spotter comprises an outlet cavity defined at least in part by a spotting orifice, a first opening, and a second opening. The spotter also comprises a first conduit fluidly coupled to the first opening and a second conduit fluidly coupled to the second opening. The spotter is adapted so that fluid flowing through the first conduit and the second conduit is communicated among the first opening, the second opening, and a submerged deposition surface when the sealing orifice is sealed against the submerged deposition surface to form a deposition spot on the submerged deposition surface. The submerged deposition surface is within a liquid such that the liquid covers the deposition spot upon removal of the orifice from the deposition surface.
US10300449B2 Neutralization plant
The invention relates to a neutralization plant (100) comprising at least one reaction chamber (102) having a first feed (114) for an acid-containing product and at least one further feed (116) for a base-containing product, wherein at least one of the feeds (114, 116) comprises at least one valve means (118, 120) for controlling the inflow amount into the reaction chamber (102), wherein the ion controller apparatus (104, 204, 205) comprises at least one evaluation device (106, 206) set up for determining at least one actual ion concentration based on an actual pH of the mixture (122) present in the reaction chamber (102) and wherein the ion controller apparatus (104, 204) comprises at least one ion controller device (108, 208) comprising at least one ion controller (110, 210.1, 210.2, 211) set up for controlling the valve means (118, 120) according to the actual ion concentration and a target ion concentration.
US10300446B2 Catalytic reactor
A catalytic reactor may have at least one reactor module and a shell that extends about a reactor center axis. The reactor module may include a gas distribution chamber, a gas collection chamber, and a catalyst. The gas distribution chamber may be connected to a shell-side gas feed. The gas collection chamber may be connected to a shell-side gas discharge. A catalyst bed between the distribution and collection chambers may extend transversely to the reactor center axis. The gas distribution and collection chambers are bounded by the catalyst bed and reactor walls. The gas feed either opens into the gas distribution chamber on the shell side or is connected to a pipe length that extends towards the reactor center axis and opens into the gas distribution chamber in the region of the reactor center axis. A height parallel to the reactor center axis of the gas distribution chamber reduces towards the reactor center axis starting from a mouth of the gas feed in the case of a shell-side connection.
US10300443B2 Spray-drying process
The process comprises delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, atomizing the spray solution into droplets within the spray-drying apparatus to remove at least a portion of the organic solvent from the droplets to form a plurality of particles, and collecting the particles. The spray solution may be formed by forming a feed suspension comprising the active agent, the matrix material, and the organic solvent, wherein the feed suspension is at a temperature T1, and directing the feed suspension to a heat exchanger, thereby increasing the temperature of the feed suspension to a temperature T2, wherein T2 is greater than T1, and the spray solution is at a pressure greater than the vapor pressure of the organic solvent at T2, such that the active agent and matrix material are soluble in the organic solvent at T2.
US10300442B2 Air void-forming material for cementitious systems
An air void-forming agent, more particularly for cementitious systems, contains at least one air void-forming material with foaming effect, at least one air void-forming material with defoaming effect, and water.
US10300440B2 Beverage container and lid assembly
A beverage container may comprise a beverage container lid assembly comprising at least one concentrate well to hold a concentrate vessel, a concentrate vessel retainer for each concentrate well to secure the concentrate vessel in the concentrate well, a feed line for each concentrate well comprising a feed line needle to puncture the concentrate vessel in the at least one concentrate well, a Venturi mixer in fluid communication with each feed line, a mixing valve in fluid communication with each feed line, wherein fluid flows from the concentrate vessel to the Venturi mixer when the mixing valve is open and the concentrate vessel is punctured by the feed line needle. Methods of using the beverage container and beverage container lid assembly are also described.
US10300436B2 Membrane system to treat leachate and methods of treating leachate
Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.
US10300435B2 Ammonia generation apparatus and ammonia generation control apparatus
An ammonia generation apparatus is disposed in a stage after a urea water injection unit. The ammonia generation apparatus includes a main body which has an introduction opening for introducing exhaust gas, a discharge opening for discharging the exhaust gas, a first flow passage and a second flow passage which communicate with the introduction opening and the discharge opening and which are separated from each other. The ammonia generation apparatus includes a heating unit disposed in the first flow passage, and a first changeover section which is disposed on one side of the main body where the introduction opening is provided and which can switch the exhaust gas flow passage between the first flow passage and the second flow passage.
US10300433B2 Vacuum pumping and abatement system
The present invention relates to a vacuum pumping and abatement system for evacuating processing gas from a process chamber and removing noxious substances from the processing gas. The present invention also relates to a method of purging a vacuum pumping arrangement. The present invention seeks to reduce the cost of ownership and operation and carbon footprint of such systems, by providing a vacuum pumping and abatement system for evacuating processing gas from a process chamber and removing noxious substances from the processing gas, comprising a vacuum pumping arrangement for evacuating processing gas from a process chamber; a source of compressed air for purging the vacuum pumping arrangement during evacuation; and a burner for receiving processing gas and compressed air from the vacuum pumping arrangement and removing noxious substances therefrom by burning the processing gas in oxygen wherein at least some of the oxygen that supports combustion is derived from the compressed air.
US10300426B2 Filters, mounts and methods of mounting filters
A grease filter for installation within an aperture of an exhaust hood overlying kitchen equipment where heat or flame may occur, the grease filter comprising an external frame assembly, a UL 1046 listed grease filter, and a removable perforated insert. The external frame assembly defines a pathway for airflow therethrough and partially defines a first chamber of the grease filter and a second chamber of the grease filter. The UL 1046 listed grease filter being disposed within the first chamber of the grease filter and being secured within the external frame assembly. The removable perforated insert being disposed within the second chamber of the grease filter and wherein the external frame assembly is configured to allow the removable perforated insert to be removably installed within the second chamber in a spaced relation from the UL 1046 listed grease filter.
US10300425B2 Apparatus for removing oil and moisture from a gas
An apparatus removing air from pressurized gas, including a pressure housing removably securable to a connection cap, a removable filter housing in the housing with moisture removing material in the filter housing, and an external indicator indicating that the apparatus is not removing at least some moisture. The cap includes an air flow exit for air which has passed through the filter housing. The indicator is on the cap and includes visible material which changes color when moisture is present. An aspirator tube diverts some air flow from the cap air flow exit into the indicator visible color changing material. The filter housing is transparent or translucent and includes oil removing material and a sintered disk before the moisture removing material.
US10300421B1 Dust collector air inlet control system
A dust collector includes a pneumatic duct chamber and a bag house interconnected by a valve assembly to provide incremental and varying air pressure within the bag house to prevent damage to the filter bags disposed within the bag house due to sudden changes in air pressure.
US10300417B2 Filter element and filter arrangement
A filter element (3), in particular an air filter element, for a filter arrangement (1), having a frame (6) that has at least one contact surface (11) for contacting a clamping surface (30) of at least one clamping element (27, 28) of the filter arrangement (1), wherein the at least one contact surface (11) includes straight segments (12, 13, 14) and oblique segments (15, 16) arranged between the straight segments (12, 13, 14), and wherein the straight segments (12, 13, 14) are arranged such that the clamping surface (30) when the latter is displaced relative to the at least on contact surface (11) essentially exclusively contacts the oblique segments (15, 16).
US10300411B2 Filtration system and method
Method and apparatus are provided for treating and removing particulate matter from fluid or treating and removing fluid from a recoverable particulate matter from fluid circulating into, through and out of an industrial operation, and for washing a disposable cartridge filter used therein. The influent fluid is maintained at a flow rate such that the differential pressure across the cartridge filter is no greater than 10 psi to prevent the buildup of non-porous filter cake. A pressure detecting mechanism and method is also provided to detect the amount of deposited particulate matter inside the cartridge filter, so that an operator can determine whether the cartridge filter should be taken out to remove or recycle the deposited particulate matter.
US10300403B2 Sealing configuration with metal-coated structure
A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.
US10300400B2 Wet evaporation-based cold concentration system
The present invention relates to a wet evaporation-based cold concentration system, which is mainly applied to the technical field of air conditioners, and particularly applied to the technical field of heat-source tower heat-pump air conditioners. By utilizing a wet evaporation theory, a low-temperature low-concentration anti-freezing solution is enabled to contact low-temperature air in a wet evaporator to perform the heat and mass transfer, and water in the anti-freezing solution is vaporized at a low temperature into the air, thereby obtaining the high-concentration anti-freezing solution. By reasonably utilizing the concentration pool and the storage pool, the low-concentration anti-freezing solution is separated from the high-concentration anti-freezing solution, thereby achieving a purpose of simultaneously concentrating and storing the anti-freezing solution
US10300396B2 Game apparatus, controlling method for game apparatus, and program
A game apparatus is provided which promotes use of a function suitable for a user in response to a usage situation of a function provided in the game apparatus. The game apparatus includes a function usage situation management table for managing a usage situation of a function provided in the game apparatus by a user, a condition decision unit for deciding, in response to the usage situation of the function by the user, whether or not each of a plurality of messages regarding the function stored in an associated relationship with given instructions by the user is to be displayed in response to the corresponding given instruction, and a message display controlling unit for displaying one of the plurality of messages which is decided so as to be displayed in response to the given instruction by the user.
US10300394B1 Spectator audio analysis in online gaming environments
An audio analysis system that may analyze participant audio input in a game spectating environment. The audio analysis system may receive audio input for participants (broadcasters and/or spectators) in a game spectating system. The audio analysis system may analyze the audio input to generate audio analysis information for broadcasts, and provide the information to the game spectating system. The audio analysis information may be applied in the game spectating system in various ways. For example, the information may be used to determine active or popular broadcasts, broadcasters, games, and/or recordings of broadcasts, and the active or popular content may be indicated to spectators via a game spectating user interface. The audio analysis system may provide an application programming interface (API) to receive the audio input and to provide audio analysis information.
US10300392B2 Virtual golf simulation apparatus and method for supporting generation of virtual green
Disclosed herein are a virtual golf simulation apparatus and method. The virtual golf simulation apparatus includes an image processing unit, a manipulation unit, and a green setting unit. The image processing unit provides an image of a basic set green on which a user will perform putting. The manipulation unit provides an interface that enables the user to set the lie of the basic set green. The green setting unit generates a user-set green by processing received setting information via the manipulation unit. The image processing unit provides the image of the user-set green.
US10300391B2 Management device, management method, terminal device, control method, and program
A management device includes: a controller configured to control an invitation processing for introducing a first application from a first terminal of a first user to a second terminal of a second user. The first application and a second application have been executed in the first terminal. The first and second users are inter-related with respect to the second application. The controller further includes: an invitation request receiver configured to receive, from the first terminal of the first user, an invitation request information for inviting the second user to the first application; and an invitation notifier configured to transmit, to the second terminal of the second user, an invitation notification information that is based on the invitation request information for inviting the second user that has been received by the invitation request receiver.
US10300388B2 Systems and methods for improving fitness equipment and exercise
The present invention provides systems for and methods of playing a video game that includes providing a game character having a virtual appearance characteristic, receiving an input signal indicative of a user exercise performance level, and altering the virtual appearance characteristic in response to receiving the input signal. Numerous other aspects are disclosed.
US10300386B1 Content item instance scaling based on wait time
Techniques for wait time based scaling of content item instances are described herein. In some examples, a customer of a computing service provider may select a wait time threshold for joining one or more of the customer's content items that are hosted by the computing service provider. When a joining user logs-in and requests to join a content item, a calculation may be made regarding an estimated wait time for the user to join one or more existing content item instances. The estimated wait time may then be compared to the wait time threshold. A determination may then be made regarding whether or not to launch a new content item instance in response to the user's join request. In some examples, this determination may be based, at least in part, on the comparison of the estimated wait time to the wait time threshold.
US10300384B2 Game processing system, game processing program, and game processing method
A game processing system that controls a display to display a plurality of graphic forms each indicating an identifier; identifies a trajectory of a continuously drawn input selecting a plurality of the graphic forms; identifies the identifiers of the graphic forms corresponding to the input trajectory; identifies at least a first command based on an arrangement of the identifiers when detecting an end of the input; and controls a game operation of attacking an opponent based on the command.
US10300383B2 Game system, game device, storage medium storing game program, and game process method
An example game system includes a controller device, and a game process section for performing a game process based on an operation on the controller device. The controller device includes a plurality of direction input sections, a sensor section for obtaining a physical quantity used for calculating an attitude of the controller device, and a display section for displaying a game image. The game process section first calculates the attitude of the controller device based on the physical quantity obtained by the sensor section. Then, the game process section controls an attitude of a virtual camera in a virtual space based on the attitude of the controller device, and controls a position of the virtual camera based on an input on the direction input section. A game image to be displayed on the display section is generated based on the position and the attitude of the virtual camera.
US10300376B2 Display device, display method, and non-transitory storage medium
A display device comprises a display, a storage configured to store a game video of a game of baseball captured in advance and scorebook data corresponding to the game, and a controller configured to extract from the game video, when score information of a specific player included in the scorebook data is selected, a displayed video including an at-bat video of the specific player in an at-bat related to the selected score information, and when the specific player advanced to base, also a base-running video of the specific player related to the selected score information as a runner in the at-bat to cause the display to display the displayed video.
US10300371B2 Method and system for interacting with a virtual environment
A system for providing a more personalized virtual environment for a user, the system including one or more sensing devices that detect one or more physical, physiological, or biological parameters of the user and transmit the same to a game console or virtual reality controller that produces the virtual environment. The game console or virtual reality controller can analyze the sensor data and adjust one or more aspects of the virtual environment as a function of the sensor data. For example, the difficulty level or scariness level of a game can be decreased if the heart rate of the user exceeds a predetermined threshold.
US10300370B1 Advanced gaming and virtual reality control using radar
Techniques are described herein that enable advanced gaming and virtual reality control using radar. These techniques enable small motions and displacements to be tracked, even in the millimeter or submillimeter scale, for user control actions even when those actions are optically occluded or obscured.
US10300368B1 Holiday toss game
A tossing game having a tree structure with branches that extend from a tubular post and which is vertically supported by a stand such that the tree structure can rotate. Each branch has a wire-way and an external target. A light is located on the tree structure. A control module having a counter with a preset counter number and a motor and gear assembly is attached to the tree structure. The control panel is in electrical communication with each target and with the light. The counter counts the number of times a game piece strikes a target. When the counter reaches the pre-determined number the control module lights the light. The motor and gear assembly rotate the tree structure on the stand.
US10300361B2 Ball game training
A method for ball game training, the method comprising steps executed by at least one computer, the steps comprising: receiving image data of a player and a ball, the image data being captured using at least two cameras, using the received image data, tracking motion of the player and motion of the ball in three dimensions, based on the tracked motions, predicting a position of the player and a trajectory of the ball, and based on the predicted position and trajectory, generating a control command for at least one ball throwing machine.
US10300356B2 Golf club heads
Described are embodiments of golf club heads having an internal cavity and features that cause the golf club head to have an improved acoustic performance when striking a golf ball. Some embodiments include one or more weight tracks and/or weight ports formed in the sole for receiving adjustable weights. The golf club heads can include one or more internal ribs, thickened wall regions, and/or posts positioned within the cavity that increase the rigidity of the club head and improve the acoustic performance of the club head when striking a ball.
US10300355B2 Golf club heads with cavities and inserts and related methods
Golf club heads with cavities and inserts, and methods to manufacture golf club heads with cavities. Various embodiments include a golf club head comprising a body. The body comprises a strikeface at a front of the golf club head, a backface opposite the strikeface, a heel region, a toe region opposite the heel region, a sole, a rear portion at a rear of the golf club head, and a cavity located between the backface and the rear portion. In many embodiments, the body further comprises an insert within the cavity.
US10300346B2 Deformable toy
Embodiments of the present invention provide a toy deformable to several structural configurations. The toy includes two endcaps connected by a plurality of pliable ribs. The toy may be deformed into a low-profile configuration by pressing the endcaps together, the ribs bending outward to accommodate the deformation. The toy may be deformed into a high-profile configuration by squeezing the ribs together, the endcaps being pushed apart to accommodate the deformation. While pressure is not applied to the toy, the toy may enter a non-deformed configuration wherein the ribs and the toy as a whole take on a substantially spherical form. A retention device may also be utilized to confine the toy to a specific configuration.
US10300337B2 Walking training apparatus and state determination method
A walking training apparatus 1 includes a leg robot 2 attached to a leg of a walking trainee, a motor 261 configured to rotationally drive a knee joint 22 of the leg robot 2, a control unit 332 configured to control the motor 261 so that the motor 261 rotationally drives the knee joint 22 in a leg-idling period in a gait motion of the walking trainee, a motor torque detection unit 262 configured to detect a motor torque, the motor torque being a torque generated by the motor 261, and a determination unit 333 configured to determine whether or not the walking trainee is in a spasticity state or a rigidity state by using a value of the motor torque detected in the leg-idling period by the motor torque detection unit 262.
US10300320B2 Aqua exercise equipment
An aqua resistance dumbbell comprises a tubular wall that provides a bore for receiving a user's hand from each end of the bell. A rod is located within the bore and extending laterally across the bore to be gripped by a user with one or both hands from one or both ends of the bore. The dumbbell has a plurality of longitudinal fins extend along the tubular wall on an outer side of the tubular wall, and at least one lateral fin that extends laterally at least part way around the tubular wall. An aqua resistance fin assembly comprises two fin components and at least one fastening member for fitting the fin components to a user's limb in a side-by-side configuration around the limb. Each fin component comprises a base adapted to fit against a user's limb and adapted to be secured to the user's limb by the fastening member, and at least two longitudinal fins and at least one lateral fin on an outer side of the base.
US10300318B2 Fire suppression system with multi-directional pass through nozzle
A fire suppression system for a gas turbine engine includes a fire suppressant delivery circuit, a first nozzle and a multi-directional nozzle. The fire suppressant delivery circuit includes and extends between an upstream inlet and a downstream distal end. The first nozzle is fluidly coupled with the fire suppressant delivery circuit and is disposed at the downstream distal end. The multi-directional nozzle is fluidly coupled with the fire suppressant delivery circuit and is configured serially inline between the upstream inlet and the first nozzle.
US10300316B2 Method to mitigate the consequences of an unconfined or partially confined vapor cloud explosion
The present invention concerns a method to mitigate the consequences of an unconfined or partially confined vapor cloud explosion due to the accidental release of a flammable gas in an open area, wherein: means capable to release a flame acceleration suppression product are dispersed in said area, a signal is generated by a detector of said flammable gas release, or by an operator, or by an approaching flame or by the explosion itself, or by any combination thereof, said signal activates the release of the flame acceleration suppression product in said area and in a sufficient amount to transform the flammable cloud into a mixture of flammable product, air and said flame acceleration suppression product to prevent flame accelerations in an unconfined vapor cloud explosion but to let the flammable product burn in case of ignition. In a specific embodiment the release of the flame acceleration suppression product is made by a signal generated by a detector of said flammable gas release or by an operator and before ignition or beginning of an explosion.
US10300314B2 Safety anchor assembly of fall-protection lifeline system for workers
A safety-anchor assembly of a fall-protection lifeline system for workers configured to be implemented in a work area defining a lower surface and an upper surface spaced from the lower surface, the lower and upper surfaces of the work area each substantially planar and oriented substantially parallel with each other. The safety-anchor assembly includes a base tube and a staff tube adjustably attached to the base tube to form a post shore extending under compression pressure between and frictionally supported upon the lower and upper surfaces of the work area to prevent movement of the post shore with respect to the lower and upper surfaces, an acute angle of about eighty-one degrees being defined between the post shore and the lower surface of the work area and a corresponding obtuse angle of about ninety-nine degrees being defined between the post shore and the upper surface of the work area.
US10300312B2 Regulator assembly for breathing mask
Regulator assemblies for breathing masks of aircraft crewmembers are described, with such an assembly including a mode selection knob mounted on a support. The knob is movable between at least two positions, allowing an associated regulator to operate in at least two modes of supplying breathing gas to a crewmember. One or more protrusions of the knob, when contacted by fingers of the crewmember, may bias the knob toward a particular one of the at least two positions.
US10300311B2 Roses iron curtain entry tool
The iron entry tool is a multifunctional device for building and vehicle forced entry, flow path blocking, rescue tarp, patient carrier. The entry tool comprises a modular structure that can fit into a wide variety of building openings and vehicle doors that are cut out under traffic collision incidents. The power alarm system of the tool provides critical safety features for rapid egress of firefighters. The canvas of the entry tool can be conveniently rewound to provide an user an efficient way to store and carry the Roses iron entry toll.
US10300310B2 Implants using ultrasonic backscatter for sensing physiological conditions
Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.
US10300308B2 System, apparatus and method for high-intensity focused ultrasound (HIFU) and/or ultrasound delivery while protecting critical structures
A method for delivering ultrasound can include positioning at least a focal zone of a transducer of an ultrasound probe proximate to targeted tissue of a patient. The method can include supplying power to the transducer to deliver ultrasound energy from the transducer to a first portion of the targeted tissue for a predetermined amount of time to create a first focal lesion in the targeted tissue. The method can include at least temporarily ceasing power to the transducer so as to at least temporarily cease delivery of ultrasound energy from the transducer to the targeted tissue. The method can include supplying power to the transducer to deliver ultrasound energy from the transducer to the targeted tissue at least substantially continuously and along a predefined treatment path.
US10300307B2 Focused ultrasound system for small bore imaging
A focused ultrasound (“FUS”} system capable of use in a small bore imaging system, such as a small bore magnetic resonance imaging (“MRI”} system is provided. The FUS system generally includes an ultrasound transducer whose position is adjusted by a positioning system. The positioning system is sized to fit within the bore of the small bore imaging system. For instance, the positioning system can fit within a diameter of 150 millimeters or less.
US10300302B2 Particle beam transport system, and segment thereof
Provide a particle beam transport system that contribute to reduction of construction period and cost for a particle beam treatment facility including plural treatment rooms accommodating a particle-beam irradiation equipment.A particle beam transport system 10 includes: a main line 31 configured to transport a particle beam generated by an accelerator outward; a branch line 22 branching from the main line 31; irradiation equipments 30 (30a-30d) provided at respective ends of the branch line 22 and configured to irradiate a patient with the particle beam, wherein at least a part of the main line 31 and the branch line 22 is configured as plural segments 20; and beam characteristics of the particle beam of each of the plural segments 20 are substantially equal at both ends.
US10300298B2 Light therapy platform system
Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly including a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed so that the reflective surface is relatively smooth and seamless towards the patient. The walls have a malleable rigidity for flexible adjustability relative to the user, and the device is mounted to the user with a frame.
US10300285B2 Impedance-based allocation of electrical stimulation to electrode clusters
Electrical stimulation sources and amplitudes are allocated to implantable electrodes based on impedance values for controlled delivery of electrical stimulation therapy to a patient. Allocation may include assigning implantable electrodes, in a group of active electrodes, to clusters based on impedance values of the electrodes, coupling the electrode clusters to respective stimulation sources, and defining respective stimulation amplitudes delivered by the stimulation sources to the electrode clusters. Each cluster may include electrodes having relatively similar impedance values, such that electrodes in each cluster present less variation in impedance relative to impedance variation across the group of electrodes. With reduced variation in impedance, in some examples, variation in current outflow through electrodes in each cluster may be reduced, promoting more uniform distribution of stimulation current across the group of active electrodes and a more uniform stimulation field.
US10300281B2 Modulating afferent signals to treat medical conditions
This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.
US10300278B2 Systems and methods for programming a neuromodulation system
A method of operating an implantable neuromodulator includes calculating an index for each of a plurality of modulation parameter sets, wherein each modulation parameter set includes a respective plurality of modulation parameters from which the respective index is calculated, serially conveying electrical modulation energy to a patient in accordance with each of the plurality of modulation parameter sets, causing the patient to perceive paresthesia in response to the conveyance of the electrical modulation energy to the tissue in accordance with one of the plurality of modulation parameter sets, identifying the calculated index for that one modulation parameter set as a perception threshold index based on the perceived paresthesia, and storing the identified perception threshold index. The method may also include determining a new modulation parameter set based on the identified perception threshold index, and conveying electrical modulation energy to the tissue in accordance with the new modulation parameter set.
US10300275B2 Magnet installation systems and methods for use with cochlear implants
Apparatus and methods for installing a magnet into a cochlear implant.
US10300273B2 Combination therapy including peripheral nerve field stimulation
Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
US10300271B2 EMS training device, and method for protecting an EMS training device
An EMS training device includes an EMS stimulus generating unit for generating EMS stimuli following a specified excitation pattern with current pulses and/or an alternating current. EMS electrodes are attached to a living body in pairs for applying the EMS stimuli to the body. Line branches connect the EMS electrodes to the EMS stimulus generating unit to apply the EMS stimuli to corresponding EMS electrodes such that a current with a specified amplitude and frequency pattern is conducted through the body. To protect the EMS electrodes and/or other susceptible elements of the line branches from corrosion, the EMS training device has at least one measuring device for measuring a value of a resistance in the line branch, a comparison device for comparing the value with a target value, and at least one compensation device for compensating for a deviation of the actual value from the target value.
US10300258B2 Apparatus and method for natural cure of middle ear infections without antibiotics
An apparatus for natural treatment for middle ear infection has a single use sachet. The sachet has a pocket that holds a limited quantity of mustard essential oil. The sachet has a neck and a dropper and the sachet can be squeezed to flow drops for pouring into an ear canal. The sachet is put in a microwave oven just before use for only substantially 30 seconds to heat the oil and up to five drops of heated oil is squeezed into an ear canal of a person with severe ear itching indicative of a middle ear infection.
US10300256B2 Devices and methods for vascular recanalization
In some embodiments, a medical device for recanalizing a vessel having a blockage and restoring blood flow through an obstructed blood vessel includes an expandable member coupled to a core wire and a hypotube that are movable relative to each other to manipulate the expandable member between various configurations. The expandable member having a capture structure in an expanded configuration. The expandable member can include multiple interstices formed by woven mesh filaments or braided strands through which the material blocking the vessel can pass. The capture structure can include a shape on its external surface that facilitates dislodgement and capture of the material within capture spaces created by the expandable member. Some embodiments include a capture sack or cap for capturing material and preventing material from migrating down stream of the blockage. Superoxygenated blood can be infused distal to the blockage to minimize loss of function during an ischemic event.
US10300254B2 Systems and methods for treating pulmonary edema
Various systems and methods are provided for treating pulmonary edema. In general, a pump can be configured to be implanted within a patient at risk of developing edema. The pump can be configured to pump fluid out of the patient's lungs, e.g., out of the patient's interstitial and alveolar spaces. The pump can be configured to be fully implanted within the patient's body. The pump can be configured to continuously pump fluid, or the pump can be configured to be selectively actuatable in response to a trigger event. In an exemplary embodiment, the pump can include an inflow port coupled to an inflow tube in fluid communication with a lymphatic vessel of the patient, and can include an outflow port coupled to an outflow tube in fluid communication with a vein of the patient.
US10300253B2 Weeping balloon with flow channels for reduced infusion pressure
Method of forming a multiple balloon catheter includes extruding a tube and a plurality of ribs through a die to form a monolithic element that spans between first and second ends with the plurality of ribs extending along the length of the tube to define a corresponding number of a plurality of channels that extend along the length of the tube. Positioning a portion of the tube into a mold and constricting a proximal end portion and a distal end portion of the tube that is positioned in the mold. Inflating the tube to produce an inner balloon having a body portion that spans between proximal and distal end portions and cutting the inner balloon to separate the inner balloon from a remainder of the tube. Disposing an outer balloon including a plurality of holes around the inner balloon and aligning the plurality of holes with the plurality of channels.
US10300250B2 Device for the treatment of varicose veins
A device for treatment of varicose veins includes a catheter (1), which can be inserted into a vein to be treated. There is a balloon (2) with at least one cutting element (3) for cutting at least part of an inner wall of the vein arranged on a proximal end (1a) of the catheter. The catheter has side openings (7a-7c), through which a sclerosing agent can be introduced into the vein. The at least one cutting element includes a cutting edge configured to cut intima and media of the vein when withdrawing the balloon from the vein after treatment with the sclerosing agent.
US10300249B2 Guidewire for cannula placement
A guidewire for backloading and inserting a percutaneous pump affixed to a cannula includes a proximal section made of a first material, with a first diameter, a rounded proximal end, and a distal end. The guidewire also includes a distal section made of a second material, with a second diameter which is greater than the first diameter, a distal end, and a proximal end abutting the distal end of the proximal section. The first material of the proximal section is selected to be softer than a material of the percutaneous pump to reduce damage to the pump during backloading. The distal section of the guidewire is configured to be stiffer than the proximal section to insert the percutaneous pump in a desired location without damaging the guidewire.
US10300248B2 Medical line retaining device and method of using the same
The invention is directed towards a retaining device for retaining at least one medical line. The retaining device includes a flexible body having a top and bottom surface with at least one slot formed in the top surface. The at least one slot extends to a depth greater than the largest medical line the retaining device is destined to be used with. An attachment mechanism is coupled to the flexible body for securing the flexible body to a supportive surface.
US10300246B2 EM guidance device for a device enabled for endovascular navigation placement including a remote operator capability and EM endoluminal imaging technique
A method and system for placing a device enabled for endovascular navigation, specifically a PICC catheter, and more broadly any device which is manipulated in over the wire or monorail fashion. Variants of the system comprise a guidewire for navigating through a patient's vasculature, having an electromagnetic (EM) based tracking components at or near the a leading end of the guidewire; an EM positioning field generator configured on a reference gantry; a computer and display configured to output position information of the guidewire leading end; and a servomotor delivery system actuator, mechanically coupled to the guidewire and configured for controlling the position of the guidewire.
US10300245B2 Therapeutic agent applicators and methods of using the same
The present application relates to applicators and methods for administering therapeutic agents to cancerous tissue. The applicators can be used to deliver radiation and additional therapeutic agents to cancerous tissue located in a subject.
US10300244B2 Unravelable catheter
The invention is a catheter, which is formed from flexible material and has two basic configurations: An initial configuration, in which the catheter is supplied to the surgeon for insertion into the lumen of a patient, resembles a tension coil spring and a final configuration, which is an essentially linear configuration that is much longer and has a considerably smaller outer diameter than when it is in its initial configuration. The catheter is adapted to undergo a transformation from the initial configuration to the final configuration as it is pulled from its proximal end in order to withdraw it from the lumen of the patient.
US10300239B2 Device and method for assisting a cough
The invention provides a device (11) for assisting a cough, based on an oscillation pressure. The oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow. The device (10) comprises a controlling unit (11), and the controlling unit (11) comprises: a first determining unit (111) for determining whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment, a second determining unit (112) for determining whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and a detecting unit (113) for detecting the start of the oscillation exhalation airflow, so as to control the valve (13) which is to be opened for starting a cough.
US10300234B2 Endoscopic bite block
According to a preferred embodiment of the present invention there is provided a bite block assembly adapted for capnography and oxygen delivery to a subject, the bite block assembly (50) including a first capnography passageway adapted for passage therethrough of exhaled breath from the subject to a capnograph and a second oxygen delivery passageway, separate from the first passageway, adapted for passage therethrough of oxygen from an oxygen source to the mouth of the subject.
US10300224B2 Medical device notification system
A system and method for communicating data from a medical device to a lighting device is provided. The system may include the medical device, the lighting device, and/or one or more interface devices. The medical device may be configured to transmit data to the lighting device, which for example, may include information relating to the medical device, dosage information, diagnostic data, medical device training feedback, health monitoring information, and/or air quality information. The lighting device may be configured to receive data from the medical device and control one or more lighting characteristics based on the received data. A characteristic of the light may include one or more of color, color temperature, intensity, flashing or steady-state, on or off, and/or the like. The system may provide for a home based adherence and/or compliance monitoring system, in which a patient's interaction with a medical device may be monitored and an alert/indication provided.
US10300222B2 Medical spraying device with pressure reduction valve, and method for producing a spray cone
A medical spraying device and method for irrigating a wound, in particular lavage system, having a liquid reservoir for a medical irrigation liquid or a connection for such a liquid reservoir, and a compressed gas reservoir. The compressed gas reservoir is connected or connectable via a pressure line to the liquid reservoir, such that the irrigation liquid can be pushed by the gas pressure of the compressed gas reservoir acting on the irrigation liquid through a nozzle in order to produce a spray cone. A pressure reduction valve is arranged in the pressure line and limits the gas pressure acting in the liquid reservoir on the irrigation liquid. The device and method produce a spray cone of a medical irrigation liquid in which a gas pressure is limited using a pressure reduction valve, wherein the gas pressure limited by the pressure reduction valve is conveyed through a pressure line to a liquid reservoir of the medical irrigation liquid. The irrigation liquid is pushed out from the liquid reservoir through a nozzle by means of the gas pressure, wherein the spray cone is produced in that the irrigation liquid flows through the nozzle.
US10300218B2 Safety assembly for a medical delivery device
A safety assembly for a medicament delivery device is presented that prevents premature activation or firing of the device during shipping or handling. The disclosed safety assembly uses a tubular cover partially contained inside of the housing of the delivery device that is axially slidable relative to the housing from a first position to a second position and then to a third position, the tubular cover having a housing nib and a cap nib, where each of the cap nib and housing nib protrudes radially outward from an outer surface of the tubular cover and are located at a proximal end of the tubular cover. In the first position the housing nib and cap nib are located outside of the housing with the housing nib abutting the terminal proximal face of the housing to prevent axial movement of tubular cover relative the housing.
US10300215B2 Needle assembly
A needle assembly includes a needle hole having an inside diameter that is greater than an outside diameter of a needle, and by a moving-side guide integrally provided to a needle tip cover being engaged with a fixed-side guide fixedly provided to the needle, a guide mechanism is provided to guide the needle tip cover from a proximal end side towards a distal end side of the needle while maintaining a state of noncontact with the needle, and to guide the needle tip cover to a position where the needle tip cover covers the needle tip while deviating the needle tip cover in a direction in which the needle hole goes away from a center axis of the needle at a position beyond the needle tip, and avoiding contact of the needle tip with the needle hole.
US10300211B2 Injection device comprising an improved delivery element
An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.
US10300204B2 Housing blank and activation member for a medicament delivery device, a kit comprising such blanks, and a medicament delivery device
A housing blank and an activation member blank for a medicament delivery device are disclosed, with a kit including a housing blank and an activation member blank, and a medicament delivery device assembled from the kit. The housing blank includes a mid portion having a through-opening for receiving a proximal end portion of a medicament container assembly, and first and second legs foldable relative to the proximal end portion. The activation member blank includes a central portion and a first and second arm foldable relative to the proximal end portion.
US10300201B2 Plunger sub-assemblies and auto-injectors having low retraction activation force
A low retraction activation force plunger sub-assembly for an automatic injector includes: a plunger outer having one or more engagement prongs, a plunger inner having a shoulder, and a plunger biasing member retained in a first energized state between said plunger outer and plunger inner when the engagement prongs of the plunger outer are releasably engaged with the shoulder of the plunger inner. An automatic injector includes a housing, an activation mechanism, an actuation mechanism, and a syringe cartridge having the plunger sub-assembly and a needle assembly, wherein the actuation mechanism includes comprises an actuation biasing member residing in an initial energized state substantially within an upper portion of an actuation pill. A method of assembling the automatic injector includes the steps of: assembling the plunger sub-assembly and inserting the plunger sub-assembly into the housing such that a proximal end of the plunger sub-assembly contacts the actuation pill.
US10300200B2 Automatic injection device with near-field communication
A automatic injection device including a housing, a firing mechanism, a near-field communication (NFC) assembly, a syringe, and a plunger. The firing mechanism is disposed within the second end of the housing and includes an activation button moveable relative to the firing body between an initial position and an actuated position. The activation button is configured to deploy the plunger when actuated. The firing mechanism includes a piercing element extending from at least the firing body or the activation button. The NFC assembly includes a film disposed proximate the piercing element and configured to be pierced by the piercing element upon actuation of the activation button. The NFC circuit is configured to indicate a film status including at least an unpierced film status before the film is pierced and a pierced film status after the film is pierced. A method of using the automatic injection device is also disclosed.
US10300199B2 Portable drug mixing and delivery device and associated methods
A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a sliding valve and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.
US10300192B2 Device for supplying and metering a fluid for medicinal purposes
A device is described for supplying and metering a fluid for medical purposes, at least comprising one pump for pumping the fluid and at least one element through which the fluid is conveyed. At least one recess is provided in the at least one element, which is tightly covered by a sensor component composed of a pressure sensitive material, wherein a material of the at least one element is harder than that of the sensor component. The device also has a force sensor with which pressure-induced changes of the sensor component in a region of the at least one recess can be measured.
US10300189B2 Whole blood separation system
A system and method are provided for controlling fouling and complement protein activation during separation of plasma from whole blood using a spinning membrane separator. The separator includes a pair of relatively rotating surfaces spaced apart to define a gap therebetween, with at least one of the surfaces comprising a membrane that allows plasma to pass therethrough but substantially prevents the passage of red cells. In accordance with the method, the membrane material and membrane fabrication technique are selected so as that the resulting membrane both resists fouling and complement protein activation. In a specific embodiment, the membrane is has a smooth surface and substantially linear pores. The pores have a nominal diameter of less than 2 microns (so as to exclude platelets) and preferably a diameter of from 0.6 microns to 0.8 microns, as may be obtained by use of track-etching. In addition, the membrane material preferably is polycarbonate, as it has been determined that polycarbonate does not activate complement proteins.
US10300188B2 Extemporaneous preparation of autologous fibrin
An Autologous fibrin is prepared extemporaneously from either a full blood sample or a prepared sample of poor platelet plasma wherein the latter is subjected to a dedicated treatment and combined isolation process performed by a removable single-use device wherein blood or plasma components are separated and subsequently treated individually to be eventually combined by the user outside the system. The system includes a platform and a removable single-use device both being designed to cooperate mechanically.
US10300186B2 Guidable intravascular blood pump and related methods
An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
US10300184B2 Flow estimation using hall-effect sensors
Methods and apparatus for estimating flow rate in a blood circulation assist system employing impeller eccentricity. A method includes magnetically rotating an impeller within a blood flow channel of a blood pump. The impeller is levitated within the blood flow channel transverse to the impeller axis of rotation. A rotational speed for the impeller is determined. At least one impeller transverse position parameter is determined. The at least one impeller transverse position parameter is based on at least one of (1) an amount of a bearing current that is used to levitate the impeller transverse to the impeller axis of rotation, and (2) a position of the impeller within the blood flow channel transverse to the impeller axis of rotation. A flow rate of blood pumped by the blood pump is estimated based on the impeller rotational speed and the at least one impeller transverse position parameter.
US10300182B1 Antimicrobial device for wound care
A wound care device includes a flexible cover having a concave interior surface and a flange configured for sealing engagement with the skin of a patient so that the device can be affixed to the skin of the patient. An inlet tube is in fluid communication with the interior thereof and configured to deliver a fluid compound thereto. An outlet tube extends from the flexible cover and is in fluid communication with the interior thereof to allow aspiration of fluid from within the flexible cover. A programmable system delivers one or more of oxygen, saline, medicaments, UV light, and ultrasonic vibration on a schedule predetermined by a user of the device.
US10300178B2 Method for providing negative pressure to a negative pressure wound therapy bandage
A method for providing a negative pressure wherein a pump is cycled on and off to achieve a target negative pressure, which is set slightly lower than the therapeutic negative pressure. A device determines the actual pressure by averaging samples which may occur at a different rate than the pump cycle.
US10300176B2 Catheter lock solution formulations
A liquid excipient is added to a lock solution formulation containing a lower alcohol and an anti-coagulant, antibiotic, and/or anti-microbial, such as the ethanol and tri-sodium citrate lock solution formulation, to prevent citrate from crystallizing in catheters made from silicone. The locking solution could include a liquid excipient, such as glycerol, polysorbate-20, or polyethylene glycol (PEG)-400, along with a lower alcohol, such as ethanol, and an anti-coagulant, such as tri-sodium citrate, antibiotic, and/or anti-microbial.
US10300167B2 Functionalized calcium phosphate artificial bone and joint compositions and methods of use and manufacture
The present invention provides a functionalized composition and resulting functionalized body or prosthesis for in vitro and in vivo use comprising at least one calcium phosphate containing phase that is functionalized with a linker group comprising at least one of an organic acid molecule, a phosphonic acid, an amine, N,N-dicyclohexylcarbodiimide, and 3-maleimidopropionic acid N-hydroxysuccinimide ester, and combinations thereof, and one or more of a chemical and/or a biologically active moieties, wherein the linker group provides for a reactive location for the attachment of the chemical or biologically active moiety, or both, to the calcium phosphate containing phase, and optionally including an unmodified and/or modified calcium aluminate containing phase. Methods of manufacturing a functionalized artificial prosthesis and methods of repairing a bone, vertebrae, or tissue structures are provided.
US10300164B2 Absorbent article with tackifier-free adhesive
Disposable absorbent articles assembled from a collection of components using an adhesive comprising an amorphous polyolefin composition and a heterophase polyolefin composition comprising amorphous character and crystalline blocks.
US10300162B2 Disinfectant wipe dispenser
A disinfectant wipe dispenser is provided comprising a container having first and second compartments, the first compartment being dimensioned to store a supply of wipes in use; and, separated by a baffle including one or more channels communicating between the compartments. The first compartment has an outlet through which wipes may be successively drawn; and, the second compartment is dimensioned to receive one or more portions of a disinfectant composition comprising a peroxy activator, a peroxy compound and optional further excipients, selected so that addition of the dosage form to a predetermined quantity of water produces a disinfectant solution containing peracetic acid at a concentration of at least about 1000 ppm. The channels communicate between the compartments and allow flow of water and aqueous disinfectant between the compartments, and have a maximum dimension configured to prevent movement of particles of disinfectant sediment from the second compartment to the first compartment.
US10300161B2 Method and apparatus for sanitation of ice production and dispensing system
An ice maker includes an ice making unit comprising an evaporator connected to a refrigeration system, an ice holding bin, a sump, a pump, a drain valve, an ozonated water source, and a controller. The controller activates the ozonated water source supplying a first volume of ozonated water to the sump, thereafter activates the pump to circulate the first volume of ozonated water from the sump to the ice making unit, once a predetermined sterilization time has been reached, the controller turns off the pump and drains the first volume of ozonated water from the sump. The controller initiates an ice making mode, and activates the ozonated water source to supply a second volume of ozonated water to the sump, thereafter activates the pump to circulate the second volume of ozonated water from the sump to the ice making unit forming ozonated ice on the evaporator, and initiates an ice harvest mode to remove the ozonated ice from the evaporator and delivers it to the ice holding bin.
US10300151B2 Methods and systems for noninvasive fluorescence-based functional imaging of kidneys
Methods and systems for evaluating renal function of a live subject. The method includes intravenously administering nanoparticles of a noble metal to the kidney of the live subject, followed by illuminating the kidney with a near infrared excitation wavelength such that the nanoparticles in the kidney fluoresce, and finally detecting presence or absence of nanoparticle fluorescence in the kidney. Detecting presence or absence of nanoparticle fluorescence includes obtaining at least one image of the kidney through the subject's skin.
US10300148B2 Messenger RNA nanoparticles and preparation method therefor
Disclosed are nanoparticles that are introduced into cells and express a specific protein and a manufacturing method thereof. More particularly, the present invention relates to mRNA nanoparticles, which increase the expression of a specific protein capable of stimulating the cellular immune system to induce cellular immune responses and are thus applicable to treat a variety of diseases, do not require passage across the nuclear envelope because a desired gene is delivered not as plasmid DNA itself but in the form of mRNA, thus improving the efficiency of protein expression, and the nanoparticles are generated through a one-step process with a relatively small amount of plasmid DNA via rolling circle transcription (RCT), thereby providing a simple and economical process for gene delivery. The present invention is also concerned with such mRNA nanoparticles.
US10300145B2 Synthetic nanoparticles for delivery of immunomodulatory compounds
The present disclosure provides a synthetic nanoparticle comprising a peptide nucleic acid (PNA) oligomer conjugated to a lipid, wherein the PNA oligomer noncovalently complexes with an immunomodulatory compound, thereby forming a nanoparticle. The nanoparticles are useful to elicit immune responses and can be used to treat a broad range of cancers and infectious diseases.
US10300144B2 N-terminal polysialylation
The present invention relates to a composition comprising a population of polysaccharide derivatives of a protein, wherein the protein is insulin or an insulin-like protein and the polysaccharide is anionic and comprises between 2 and 125 saccharide units, and wherein the population consists of substantially only N-terminal derivatives of the protein. Typically, the polysaccharide is PSA. The present invention also relates to pharmaceutical compositions comprising the novel compounds, and methods for making the novel compounds.
US10300140B2 Sur-binding proteins against ERBB3
Embodiments concern constructs comprising surrogate light chain sequences. In particular, embodiments concern constructs that can bind to ErbB3 and aspects relating to such constructs.
US10300138B2 Selectively altering microbiota for immune modulation
The invention relates to methods of modulating immune cells in a patient by altering microbiota of the patient. The invention also relates to methods of modulating treatments or therapies in a subject organism by altering microbiota of the subject. The invention also relates to cell populations, systems, arrays, cells, RNA, kits and other means for effecting this. In an example, advantageously selective targeting of a particular species in a human gut microbiota using guided nucleic acid modification is carried out to effect the alteration.
US10300136B2 Micromolded or 3-D printed pulsatile release vaccine formulations
Emulsion-based and micromolded (“MM”) or three dimensional printed (“3DP”) polymeric formulations for single injection of antigen, preferably releasing at two or more time periods, have been developed. Formulations are preferably formed of biocompatible, biodegradable polymers. Discrete regions encapsulating antigen, alone or in combination with other antigens, adjuvants, stabilizers, and release modifiers, are present in the formulations. Antigen is preferably present in excipient at the time of administration, or on the surface of the formulation, for immediate release, and incorporated within the formulation for release at ten to 45 days after initial release of antigen, optionally at ten to 90 day intervals for release of antigen in one or more additional time periods. Antigen may be stabilized through the use of stabilizing agents such as trehalose glass. In a preferred embodiment for immunization against polio, antigen is released at the time of administration, and two, four and six months thereafter.
US10300135B2 Multivalent glycoconjugate vaccines
The present invention refers to new conjugate antigens expressing built-in multiple epitopes and to polyvalent glycoconjugate vaccines and formulations containing the same. In addition, the present invention concerns the use of these vaccines in particular for the protection of the human population, and in particular for the protection of the paediatric population from pulmonary and systemic infections due to S. pneumoniae, N. meningitidis, H. influenzae, K. pneumoniae, M. tuberculosis, S. aureus, or from intestinal infections due to S. typhi, V. cholerae and E. coli. The present invention additionally refers to new polyvalent glycoconjugate vaccines for the protection from C. albicans and E. coli systemic and genitourinary infections or for the protection from M. bovis infections in veterinary medicine.
US10300133B2 Compositions for delivery of food allergens to the stomach
The invention relates to novel compositions and methods for diagnosing or treating food allergies. The invention particularly discloses new approaches for delivering food allergens to allergic patients by oral administration of formulations which dissolve and release proteins in the stomach. The invention allows the treatment of food allergies by delivering food allergens to the gut immune system with controlled exposure of the esophagus or oral cavity. The invention also allows to perform food challenges to assess the threshold of clinical reactivity without exposing the esophagus and oral cavity. The invention may be used in any subject, particularly human subjects, and is applicable to any food allergen.
US10300127B2 Immune complex
The present invention relates to immunogenic immune complexes, related compositions, and related methods. This invention addresses the above-described un-met need by providing an immune complex (IC) or immune complexes (ICs), which take advantages of Type II Fc receptor (FcR) interactions and signaling to elicit broader and more potent protective immune responses. In one aspect, the invention provides an immune complex comprising an antigenic agent and an isolated protein. The protein comprises an IgG Fc region and is capable of binding to a Type II Fc receptor. Preferably, the protein is an antibody or an Fc region-containing fragment thereof.
US10300117B2 Methods and compositions for improved cognition
Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides.
US10300116B2 Treatment for BK polyomavirus infection
The present disclosure provides novel compositions and methods for treating infection by a viral pathogen, e.g., a BK or JC polyomavirus, using agents having sialidase activity. In particular, the present disclosure provides methods that entail administering agents having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by a pathogen.
US10300110B2 Therapy for subarachnoid hemorrhage and ischemia
The application provides data from a clinical trial of a PSD-95 inhibitor in subjects undergoing endovascular repair of an aneurysm in or otherwise affecting the CNS. The subjects were stratified by whether the aneurysm ruptured before performing the endovascular surgery. Rupture is associated with higher mortality or increased debilitation if a subject survives. The trial provided evidence of significant benefit in subjects with and without aneurysm rupture before endovascular was surgery performed. Surprisingly, the subjects benefiting most from treatment as judged both by pathology and neurocognitive outcome were those in which the aneurysm had ruptured causing a subarachnoid hemorrhage. These data constitute evidence that a PSD-95 inhibitor is beneficial not only in ischemic and hemorrhagic stroke but in forms of hemorrhage in or affecting the CNS, particularly, subarachnoid hemorrhage.
US10300109B2 Peptidomimetic macrocycles
Disclosed are peptidomimetic macrocycles comprising a helix, such as an alpha helix, and methods of using such macrocycles for the treatment of disease such as cancer. In other aspects, the peptidomimetic macrocycle comprises an α,α-disubstituted amino acid, or may comprise a crosslinker linking the α-positions of at least two amino acids or at least one of said two amino acids may be an α,α-disubstituted amino acid. Further included is the targeting of components of the Wnt signaling pathway such as the Tcf4-/3-catenin complex.
US10300106B2 Autophagy-inducing peptide analogs
An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Beclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.
US10300099B2 Composition for the treatment and prevention of urinary tract infections
A pharmaceutical composition or dietary supplement is described that is effective in the treatment and prevention of urinary tract infections, comprising a combination of D-mannose, proanthocyanidins, hydroquinone derivatives and zinc.
US10300097B2 Process for the production of an enriched natural antioxidant mixture from a single source plant
A process for extracting antioxidants from a plant, including contacting a plant material from a guayusa plant for a first time with a solvent, thereby obtaining a first slurry, filtering said first slurry, thereby obtaining a first extract, contacting said plant material for a second time with said solvent, thereby obtaining a second slurry, filtering said second slurry, thereby obtaining a second extract, combining said first extract and said second extract, thereby generating an third extract containing at least antioxidants, xanthines, and amino acids, and substantially drying said third extract.
US10300096B2 Use of adenoviruses and nucleic acids that code for said viruses
The present invention is related to the use of a virus, preferably an adenovirus, for the manufacture of a medicament, whereby the virus is replication deficient in cells which do not have YB-1 in the nucleus, and the virus codes for an oncogene or oncogene product, in particular an oncogene protein, which transactivates at least one viral gene, preferably an adenoviral gene, whereby the gene is selected from the group comprising E1B55kDa, E4orf6, E4orf3 and E3ADP.
US10300090B2 Compositions of hematopoietic stem cell transplants
The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.
US10300089B2 Methods for high scale therapeutic production of memory NK cells
Disclosed are compositions and methods relating to the expansion of memory NK cells.
US10300088B2 Method for producing eye drops
The invention relates to a method for producing eye drops, the thus obtained eye drops and to a kit which comprises the eye drops.
US10300084B2 Methods for treating pulmonary hypertension
The present invention relates to methods for treating or preventing pulmonary hypertension, reducing mortality in a subject experiencing pulmonary hypertension, or inhibiting ADP-mediated vasoconstriction of pulmonary arteries in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising a reversible P2Y12 receptor antagonist. Also provided are related medicaments, pharmaceutical compositions, and methods for preparing the medicaments.
US10300081B2 Modified release doxycycline composition
Doxycycline formulations with a reduced food effect are disclosed. Particularly disclosed are modified release formulations which can be administered once a day and exhibit a reduced food effect. Methods of treating inflammatory conductions such as rosacea or inflammatory symptoms such as the papules and pustules of rosacea or acne vulgaris are also disclosed.
US10300075B2 Compounds that inhibit MCL-1 protein
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
US10300071B2 Compositions and methods for inhibition of mycobacteria
A composition comprising a drug selected from the group consisting of an arylphenoxypropionate derivative, an aryloxyphenoxyacetate derivative, an aryloxyphenylacetate derivative, a substituted quinol, or a salt, hydrate, or prodrugs thereof, or a combination thereof, in an amount and formulation sufficient to inhibit a mycobacterium is disclosed.
US10300069B2 Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof
Carbon monoxide-releasing organic molecules are described herein. The molecules can be synthesized prior to administration (e.g., ex vivo) or formed in vivo. In those embodiments where the molecules are formed in vivo, reactants are administered under physiological conditions and undergo a cycloaddition reaction to form a product which releases carbon monoxide. In applying such reactions for therapeutic applications in vivo, the cycloaddition and CO release typically occur only under near-physiological or physiological conditions. For example, in some embodiments, the cycloaddition reaction and/or release of carbon monoxide occur at a temperature of about 37 C and pH of about 7.4. Pharmaceutical compositions and methods for release carbon monoxide are also described.
US10300066B2 Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors
Described herein is a novel series of multi-fluoro-substituted pyrazolopyrimidine compounds or salts thereof. These compounds are Bruton's tyrosine kinase (BTK) inhibitors. These compounds may possess better BTK inhibition selectivity and pharmacokinetic properties. Disclosed herein are the synthesis methods of these compounds. Disclosed herein are novel synthesis methods of the multi-fluoro-substituted benzophenone and substituted phenoxy benzene. Also disclosed are pharmaceutical compositions comprising the BTK inhibitors described herein. The present invention also relates to pharmaceutical formulations comprising the compounds described herein as active ingredients. The present invention also includes the therapeutic methods by administering the BTK inhibitors and their formulations to treat and inhibit autoimmune disease, hypersensitivity disease, inflammatory diseases and cancer.
US10300065B2 Method of treating or prevention of atherothrombotic events in patients with history of myocardial infarction
The present disclosure relates to methods for reducing the rate of cardiovascular death, myocardial infarction, or stroke in a patient in recognized need thereof, comprising administering to the patient a pharmaceutical composition comprising 60 mg ticagrelor twice daily.
US10300064B2 Organic compounds
The present invention relates to certain PDE2 inhibitory compounds, in free or salt form, pharmaceutical compositions containing such compounds and methods for the treatment of PDE2 mediated disorders.
US10300063B2 Pharmaceutical composition not containing antioxidant and preparation method therefor
Provided are a composition containing an unstable drug against oxidation like pemetrexed with improved stability and a preparation method thereof, by removing oxygen during the preparation without use of an antioxidant. The method is readily applicable for manufacturing by freezing and degassing in a sealed chamber, and can provide formulations with significantly increased stability for the unstable drug against oxidation.
US10300062B2 Bicyclically substituted uracils and the use thereof
The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
US10300043B2 Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof
This document provides materials and methods related to bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity. For example, bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity and methods for using such bacterial compositions to improve gastrointestinal epithelial function and/or to treat gastrointestinal disorders are provided.
US10300039B2 Ferric citrate dosage forms
Disclosed herein are ferric citrate-containing tablets. In various embodiments, the tablets include ferric citrate formulations that meet certain dissolution, tableting and disintegration standards. In various aspects, the tablet formulations can include ferric citrate as the active ingredient and a binder. The formulations also can include a lubricant and/or a disintegrant (which, in some embodiments, can be the same as the binder).
US10300032B2 Controlled release dosage form
The present invention provides a simple and improved dosage form that is capable of providing a controlled release of GABAB receptor agonist contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to GABAB receptor agonist.
US10300029B2 Organ protection solutions and method of use
An organ protectant solution which is intravenously administered includes at least one oncotic agent and optionally a high concentration of cell-impermeant molecules. Together, they promote transfer of water from cells to interstitium and into the capillaries, thereby preventing or reducing cell swelling, maintaining blood circulation and oxygenation of tissues, and extending the “Golden Hour” for traumatic and/or hemorrhagic shock patients. In addition, compositions comprising PEG-20k and methods of their use for preserving and/or reanimating harvested organs ex vivo for lengthy periods of time (e.g. at least about 8-24 hours) are also provided.
US10300027B2 Effective sensitizing dose of a gelled immunomodulating topical composition
The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.
US10300023B1 Stabilized assembled nanostructures for delivery of encapsulated agents
A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as safe (GRAS), materials assemble in the presence of a stabilizing agent at an appropriate molar percentage, forming hydrogel or organo-gel with nanostructures that resist disassembly or destabilization in serum for an extended period of time. The composition is used to deliver one or more therapeutic, prophylactic, or diagnostic agents, allowing for controlled release in response to biological stimuli such as enzymes and a greatly improved dosing efficacy.
US10300017B2 Method and composition for treating cystitis
A medicament for treating cystitis and a method of treatment are provided. An agent to repair the damaged glycosaminoglycan (“GAG”) layers lining the urothelium, noted in cystitis, such as pentosan polysulfate, hyaluronic acid, chondroitin, etc., is provided in a liposomal carrier. Cystitis is treated by intravesically administering to a patient a therapeutically effective dose of the medicament.
US10300013B2 Intra-amniotic administration of EDI200 for the treatment of ectodermal dysplasias
The invention relates to methods for the intra-amniotic administration of EDA agonists, in particular EDI200. Use of the methods described allow for the design of targeted therapeutic dosing and administration regimens in order to correct or alter abnormal phenotypes associated with ectodermal dysplasias, in particular, XLHED.
US10300003B2 Hair shaping composition
The invention provides a hair shaping composition suitable for topical application to hair, the composition having a pH of 4 or less and comprising, in an aqueous continuous phase: (i) at least 0.5% (by weight based on the total weight of the composition) of one or more polyhydroxy acid lactones; (ii) at least 0.5% (by weight based on the total weight of the composition) of one or more aliphatic di- or tricarboxylic acids, and (iii) at least 0.1% (by weight based on the total weight of the composition) of glyoxylic acid or a salt or hydrate thereof.
US10299999B2 Flavour composition comprising menthol and menthane carboxamides
The invention relates to flavor compositions comprising a mixture of coolant compounds comprising menthol and a menthane carboxamide selected from N-(4-cyanomethylphenyl) p-menthanecarboxamide, 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide, or a mixture of N-(4-cyanomethylphenyl) p-menthanecarboxamide and 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide, wherein the total amount of menthane carboxamide is about 0.1 to 10%.
US10299998B2 Single phase whitening dentifrice with high purity metaphosphate abrasive
Provided is a single phase oral care composition having a whitening agent; a first abrasive selected from calcium pyrophosphate, calcium carbonate, and dicalcium phosphate; a second abrasive that may include sodium metaphosphate; an anticalculus agent; and a substantially anhydrous carrier that may include an ethylene oxide/propylene oxide copolymer. In the composition, a wt % of the second abrasive is equal to or greater than a wt % of the first abrasive.
US10299996B2 Active ingredient capsules
Active ingredient capsules are proposed which are obtainable by, with the input of mechanical and thermal energy, (a) dissolving and/or dispersing proteins, polysaccharides and cellulose derivatives in water, (b) adding the active ingredients to be encapsulated, (c) hardening the resulting coacervates with the addition of tannins and optionally (d) then subjecting them to a spray drying.
US10299989B2 Pressure-regulating vial adaptors
In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. The regulator assembly can include a valve configured to transition between a closed configuration and an opened configuration.
US10299988B2 Acupressure walking machine applying pressure to foot reflex zones
An acupressure walking machine for applying pressure to foot reflex zones is disclosed. The present invention relates to an acupressure walking machine for applying pressure to foot reflex zones, the walking machine additionally providing an embossing belt, which is made from an elastic material and circulating in a caterpillar form, to the lower side of a running belt circulating in a caterpillar form so as to restrain acupressure stones from rapidly gathering at a curved turning section, such that the uniform dispersion of the acupressure stones is induced, thereby uniformly distributing the acupressure stones placed on the running belt.
US10299980B2 Rehabilitation exercise device
A mouse-type rehabilitation exercise device includes a mouse body on which a hand is mounted, a wheel moving the mouse body, a first motor aligning a position of the wheel such that the mouse body moves to a desired direction, a second motor rotating the wheel such that the wheel aligned by the first motor moves to a desired position, a clutch disposed between the second motor and the wheel to enable and disable a power transmitting to the wheel from the second motor, and a controller controlling a driving of the first motor, the second motor, and the clutch.
US10299977B2 Multi-functional and multipositional bed
A bed includes a telescoping foot-end leg at a first end; a telescoping head-end leg at a second end opposite from the first end; a rotating frame that rotates on a lateral first axis extending between an upper portion of the foot-end leg and an upper portion of the head-end leg; and a tilting frame supported by the rotating frame. The rotating frame tilts on a second axis perpendicular to the first axis. The tilting frame is configured to support the patient's entire body. The foot-end leg and the head-end leg are configured to be telescoped while the patient is on the bed such that the height of the foot-end leg is lower than the height of the head-end leg and a slope of the first axis is at least 15 degrees.
US10299976B2 Bed for patients
An electric bed includes a basic unit and a lift unit. The basic unit includes a base, a sliding frame supported on the base, a backrest frame pivotally connected to the sliding frame, a headrest frame pivotally connected to the backrest frame, and a restraint including an end pivotally connected to the base and another end pivotally connected to the backrest frame. The backrest frame includes a lug that includes a slot. The lift unit includes a power element pivotally connected to the sliding frame, a rod operatively connected to the power element, a backrest driver pivotally connected to the rod, a headrest driver pivotally connected to the backrest driver, a backrest lever for pivotally connecting the backrest driver to the backrest frame, a roller supported on the backrest lever, and a threaded bolt inserted in the backrest driver and the slot of the lug of the backrest frame.
US10299969B2 Diaper
A diaper includes a medical pad including a piece of substrate with a major surface and an electric circuit on the major surface, a sensor connected with the electric circuit for measuring the electrical resistance of the electric circuit, and a wireless data transceiver or a radio frequency identification (RFID) tag electrically connected with the sensor for receiving results of the measuring from the sensor for subsequent transmission. The system carries out real time self-calibration to adaptively monitor the condition of the medical pad even in the face of changing environment and changing material properties.
US10299968B2 Wireless incontinence detection apparatus
A moisture management apparatus monitors an area for moisture events and wirelessly transmits moisture-related information to one or more notification devices. An embodiment of the moisture management apparatus includes a substrate and one or more sensors supported by the substrate. The sensor(s) emit wireless signals indicative of the moisture-related information. A sensor event communication system forwards the sensor signals to another device, such as a notification device. The sensor event communication system may monitor other types of patient events. Portions of the moisture management apparatus and/or the moisture event communication system may be embodied in a patient support apparatus, such as a bed.
US10299967B2 Methods and apparatuses for moving and/or transferring multiple discrete articles
Methods and apparatuses for moving and/or transferring discrete articles are described. In particular, the methods and apparatuses relate to flexible arrangements to move and/or transfer discrete articles that vary in size and/or shape with minimal to no change in equipment.
US10299961B2 System for neuroprotective therapy for glaucoma
Providing neuroprotective therapy for glaucoma includes generating a micropulsed laser light beam having parameters and characteristics, including pulse length, power, and duty cycle, selected to create a therapeutic effect with no visible laser lesions or tissue damage to the retina. The laser light beam is applied to retinal and/or foveal tissue of an eye having glaucoma or a risk of glaucoma to create a therapeutic effect to the retinal and/or foveal tissue exposed to the laser light beam without destroying or permanently damaging the retinal and/or foveal tissue and improve function or condition of an optic nerve and/or retinal ganglion cells of the eye.
US10299960B2 Customized laser epithelial ablation systems and methods
Systems and methods to treat a region of a cornea of an eye having an epithelial layer disposed over a stromal layer. The system comprises a device to map a thickness of the epithelial layer over the region of the cornea to generate a map of epithelial thickness over the region, and a laser to generate a laser beam of an ablative radiation. A movable scan component is coupled to the laser to scan the laser beam over the region. A processor system is coupled to the laser and the movable scan component, and the processor system is configured to arrange pulses of laser beam to ablate the epithelial layer of the region in response to the map of epithelial thickness.
US10299953B2 Material including pre-cut anatomical supports
A material includes a support layer comprising a single layer of woven fabric less than 30 mils thick. The support layer includes a plurality of anatomical supports each having a pair of substantially straight sides and rounded end portions and all of a substantially same size and shape. Each of the plurality of anatomical supports is at least partially disconnected from a remaining portion of the support layer. The support layer has a ratio of elongation to tensile strength (lb/in-width) that is less than 0.9 in at least one direction. The material additionally includes an adhesive layer on said support layer for adhesive attachment of said support layer to the outer skin surface of a user and a removable cover layer on said adhesive layer. The plurality of the anatomical supports in the support layer is attached to an at least partially continuous portion of the removable cover layer.
US10299952B2 Supports including dual pivot axes for hinge joint
A support for an area of a body having a hinge joint includes: a flexible, elastically stretchable framework configured to extend across the hinge joint of the area of the body; and a hinge mechanism affixed to the framework. The hinge mechanism includes a strut component and a first arm component connected to the strut component such that the first arm component is rotatable relative to the strut component only about a first pivot axis. A second arm component is connected to the strut component such that the second arm component is rotatable relative to the strut component only about a second pivot axis. The strut component is configured to extend with the framework across the hinge joint such that the first pivot axis is located on a first side of the hinge joint and the second pivot axis is located on a second, opposite side of the hinge joint.
US10299951B2 Vascular prosthetic delivery device and method of use
Methods for delivering a vascular prosthesis to a treatment site of a subject include advancing the vascular prosthesis, rotating a proximal handle in a first direction about a handle body, shifting the position of a first locking component securing the proximal handle to the push rod from a first position to a second position, rotating the proximal handle in a second direction, releasing the proximal end of the prosthesis from the apex delivery device, shifting the second locking component to disengage the push rod from the handle body; and withdrawing the push rod and the guidewire catheter from within the prosthesis, thereby delivering the vascular prosthesis to the treatment site.
US10299949B2 Release device for releasing a medical implant from a catheter, and catheter
A release device for releasing a medical implant from an insertion device, in which the implant can be released by a relative movement between a first and a second insertion element, wherein the insertion device has a proximal end, which faces the user during use, and a distal end, which is distanced from the user during use. Between the proximal and the distal end, a shortening region is provided, in which, when generating a targeted relative movement between the first and the second insertion element of the insertion device, a length of at least one of the insertion elements between the proximal end and the distal end can be shortened.
US10299945B2 Method of treating atherosclerotic occlusive disease
A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease can be formed as a thin, annular band of durable, flexible material. The tack device may also have a plurality of barbs or anchoring points on its outer annular periphery. The annular band can have a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface, in order to avoid the need to install a stent and thereby maintain a ‘stent-free’ environment.
US10299942B2 Prosthetic foot insert and prosthetic foot
A prosthetic foot insert with upper attachment member, a roof spring extending forwards from the upper attachment means, and a base spring coupled to the roof spring at least two points. A rear coupling element is provided for supporting the base spring, and a free space is formed between the coupling element, the roof spring and the base spring. The base spring, in the heel area, protrudes rearwards as a free lever beyond the rear coupling element.
US10299939B2 Bone joint replacement and repair assembly and method of repairing and replacing a bone joint
A bone joint repair and replacement assembly. A first portion comprising a bone plate is configured to attach to a distal or proximal end of a bone proximate the joint, generally coaxially with an axis defined by the bone. A second portion comprising an articular surface is configured to attach to the first portion, generally normal with respect to the axis, and inserted into the joint. Although versions of the assembly can be configured for use with several different pivotal joints, the invention is particularly suitable for full or partial replacement of an elbow, wherein the articular surface is pivotally attached to the first portion. Another embodiment of the invention is provided to repair a fractured bone head proximate the joint, and still another embodiment of the invention is provided to repair rotator cuff-related shoulder injuries.
US10299938B1 Dynamic intervertebral spacer implant
Intervertebral spacer implants with dynamic load spreading features responsive to external loads and having attachment mechanisms. The dynamic load spreading features having a native state and a loaded state, which complements vertebral end plate geometry and disperses load to the epiphyseal rim.
US10299936B2 Distance interbody device for introducing a biomaterial to a vertebral body and a method of its use
A distance interbody device for introducing a biomaterial to a vertebral body includes a shaped body and a dispense mechanism operable to dispense biomaterial. The shaped body includes a top side, a bottom side, and a lateral wall forming a peripheral wall that extends between the top and bottom sides. The shaped body is provided with at least one through channel and at least one anchoring element. The through channel includes an internal reservoir for the biomaterial. The through channel passes through the anchoring element to at least one outlet opening located in the at least one anchoring element.
US10299935B2 Adjustable arcuate implant
An expanding implant (10, 10′, 10″) includes a base (12) having a contact surface (14) for contacting a first region of tissue and a displaceable portion. (24) having a contact surface (26) for contacting a second region of tissue. The base (12) has a proximal portion (16) in sliding engagement with, a distal portion (18) so as to define an arcuate path of relative motion between the proximal and distal portions. The base assumes an initial state with a first arcuate extent and is adjustable towards a second State by changing an: extent of overlap between the proximal and distal portions to vary an. arcuate extent of the base. First and second rigid linking segments (20, 22) are in articulating connection with the distal and proximal portions of the base, and with the displaceable portion such that adjustment of the base from the initial state towards the second state causes an increase in a distance between the contact surfaces of the base and the displaceable portion.
US10299933B2 Artificial disc replacements with natural kinematics
This invention improves upon prior art total disc replacements (TDRs) by more closely replicating the kinematics of a natural disc. The preferred embodiments feature two or more fixed centers of rotation (CORs) and an optional variable COR (VCOR) as the artificial disk replacement (ADR) translates from a fixed posterior COR that lies posterior to the COR of the TDR to facilitate normal disc motion. The use of two or more CORs allows more flexion and more extension than permitted by the facet joints and the artificial facet (AF). AF joint-like components may also be incorporated into the design to restrict excessive translation, rotation, and/or lateral bending.
US10299932B2 Elbow prosthesis
The present invention concerns an elbow prosthesis, including: at least one ulnar section, including a stem portion extending along a substantially longitudinal axis (x-x) between a proximal end and a distal end; at least one humeral section, including a stem portion extending along a substantially longitudinal axis (y-y) between a proximal end and a distal end, the distal end of the humeral section delimiting an engagement seat with the proximal end of the ulnar section; articulation pin between the distal end of the humeral section and the proximal end of the ulnar section, available along an axis (z-z) perpendicular with respect to the substantially longitudinal axis (y-y) of the humeral section. The proximal end of the ulnar section is engageable in the housing seat.
US10299929B2 Bone void forming apparatus
A bone void forming assembly includes a support member having a head portion and an elongate portion extending therefrom. A guide member is connected to the support member and has a guide body including a channel extending therethrough. The channel defines an axis offset and obliquely angled relative to an axis of the elongate portion. The assembly also includes reamer having a cutting head and a stop member. A bushing is slidably connected to the reamer between the stop member and cutting head and is slidably connectable to the guide body via the channel.
US10299926B2 Transcatheter valve with paravalvular leak sealing ring
A prosthetic heart valve includes a collapsible and expandable stent extending from an inflow end to an outflow end and a plurality of prosthetic valve leaflets coupled to the stent. The prosthetic heart valve may also include a sealing ring coupled to the inflow end of the stent, the sealing ring comprising a tube extending circumferentially around the inflow end of the stent. The tube may be formed from a wire coiled into a repeating shape, such as a rectangle or a diamond, so that the tube is collapsible. A covering may at least partially surround the tube. The sealing ring may include a first filler positioned within the tube and/or a second filler positioned between the tube and the covering.
US10299925B2 Collapsible prosthetic heart valves
A prosthetic heart valve includes a collapsible and expandable support frame extending between an inflow end and an outflow end and a plurality of commissures, wherein each commissure is formed with an elongate opening. A plurality of leaflets are supported inside the support structure and operative for allowing flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end. Each of the plurality of leaflets includes tabs. The prosthetic heart valve includes at least a first panel of fabric covering the opening of a first commissure. The first panel of fabric is attached to a first tab of a first leaflet via a suture extending orthogonal to the first panel of fabric, wherein the first panel of fabric is positioned radially outwardly of the first tab.
US10299918B2 Vena-caval device
Apparatus and method are described including identifying a subject as suffering from a condition that causes the subject to have elevated central venous pressure. In response thereto, a device is placed inside the subject's vena cava such that an upstream end of the device is placed at a location upstream of junctions of the vena cava with all of the subject's renal veins. The device defines a passage through the device, at least a portion of the passage converging in a direction from an upstream end of the device to downstream end of the device. Other applications are also described.
US10299917B2 Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.
US10299911B2 Aspherical multifocal intraocular lens
A multifocal intraocular lens has an anterior lens surface which includes a first optic of a first radius and a second optic of a different radius. The posterior surface of the lens include an aspheric surface.
US10299909B2 Optical device and method for modifying the refractive index of an optical material
An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
US10299906B2 Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
A blood filter delivery system for delivering a filter into a vein from either a femoral or jugular access. The preferred system includes an introducer and a push-rod with a spline member disposed along the push-rod and a pusher member disposed on a distal end. The spline member has a main body, first and second boss portions spaced apart along the longitudinal axis to provide a gap for retaining anchor members of the filter during delivery via the introducer. In an alternative embodiment, a preferred filter includes first and second filter structures diverging in opposite directions. A link is connected to portions of each of the first and second filter structures so that each filter structure can be independently collapsed into a generally cylindrical shape.
US10299891B2 System and method for ordering and manufacturing customized orthodontic appliances and product
A prescription management system is used by an orthodontic or dental lab and a plurality of prescribing users who send prescriptions for customized orthodontic or dental appliances to the lab. The prescriptions are stored in a database selectively accessible by the lab and plurality of prescribing users. A digital workspace is provided in the system in which the lab or prescribing users may create designs for the customized appliances. The designs of the appliances are stored in the database. A tracking record of fabrication of the appliances is stored in the database. A plurality of billings are simultaneously generated in response to the submissions and storage of the prescriptions, the designs of the customized appliances and the fabrication of the designed customized appliances.
US10299890B2 Dental wedge
Disclosed is a dental wedge and system comprising a dental wedge and a tool. The dental wedge includes a spherical gripping portion at an end, which provides surfaces extending generally transverse relative to a longitudinal axis of the dental wedge. A tool is configured to engaged with the spherical gripping portion so that a user may manipulate the tool in order to manipulate the dental wedge.
US10299889B2 Dental wedges and matrix bands for use in direct composite restoration techniques for anterior teeth
A wedge for use in a dental restoration procedure for an anterior tooth. The wedge includes a handle portion, a body portion coupled to and extending outward from the handle portion, and a matrix band coupled to the body portion. The body portion is adapted to be disposed in an approximal space between the anterior tooth and a tooth adjacent the anterior tooth. The matrix band is adapted to contact the anterior tooth when the body portion is disposed in the approximal space.
US10299887B2 Atmospheric non-thermal gas plasma method for dental surface treatment
The provision of dental restorations can be improved by generating a cold atmospheric plasma inside the mouth of the patient and then applying that cold atmospheric plasma onto a dental restoration site. The dental restoration site can be composed of either or both of dentin and enamel. Further, the provision of dental restorations can also be improved by introducing a dental adhesive onto a dental restoration site and treating it with a cold atmospheric plasma.
US10299884B2 Spring driven pump for dispensing discrete bursts of liquid
An oral care appliance (10) having a pump assembly (14) for delivering discrete bursts or shots of liquid. The pump assembly includes a pump housing (36) and an inlet/outlet assembly (38) at a forward end of the housing, including one-way valves (80, 82) in the inlet and outlet openings. A plunger sleeve (44) is positioned within the housing with a central opening (48) in a fluid-tight relationship with the inlet and outlet assembly. A plunger (52) includes a center portion (56), positioned in the central opening of the plunger sleeve in a fluid-tight relationship therewith. The plunger sleeve includes an outer member (54) between the plunger sleeve and the internal surface of the housing. A compressible spring (64) is positioned between a forward end of the outer member of the plunger and the rear end of the housing. A drive mechanism (72) moves the plunger rearwardly, resulting in the plunger sleeve filling with liquid by vacuum action from a reservoir (26) in the appliance, and then releases the plunger, allowing the spring to move the plunger quickly forward, forcing liquid in the plunger sleeve out through the fluid outlet in a direct burst.
US10299881B2 Marker or filler forming fluid
A solution for forming a marker or filler mass for an intracorporeal site. The solution contains a polar, water soluble non-aqueous solvent such as dimethyl sulfoxide and a bioabsorbable, essentially water insoluble polymer such as polylactic acid, or copolymers of lactic acid and glycolic acid. The solution may be delivered to the biopsy site by a suitable syringe and delivery tube. The delivery tube is preferably provided with a releasable radiopaque element on the distal tip which can be released within the polymeric marker mass formed in the biopsy cavity.
US10299879B2 System and method for aligning an elongated tool to an occluded target
Systems and methods for aligning an elongated tool to an occluded target and for striking the occluded target using the elongated tool are disclosed. The system for aligning an elongated tool to an occluded target includes an adjustment mechanism configured to adjust an angular orientation of the elongated tool relative to a pivot point spaced from the target; a 3-dimensional (3D) imaging device configured to capture a 3D image of the elongated tool and the occluded target; and a processor communicatively coupled with the adjustment mechanism and the 3D imaging device. The processor is configured to process the 3D image received from the 3D imaging device to obtain location data of the target and the pivot point; and based on the location data of the target and the pivot point, control the adjustment mechanism to adjust the angular orientation of the elongated tool relative to the pivot point to align a longitudinal axis of the elongated tool with the target and the pivot point.
US10299877B2 Package for medical device
A package including at least one bumper having an elliptical shape that extends from a first end to a second end along a first plane and having a protrusion that extends from a first front along a second plane; and a first tray having a first cavity that extends from a second front along the second plane, wherein the first cavity includes at least one groove configured and dimensioned to receive the at least one bumper is disclosed.
US10299875B2 Devices for mobility assistance and infusion management
Provided are mobility assistance devices, particularly useful in medical settings where a patient ambulation is desired but the patient remains connected to one or many medical components. The system comprises a mast connected to a base, wherein the mast is angled with respect to the base and from which any number of medical components is supported. The device geometry and connections ensure the device is extremely stable and tip-resistant. Also provided are oxygen tank holders to reliably and conveniently hold oxygen tanks and power management systems that reliably provide electrical power without impacting device performance or mobility. The device is deployable to permit conversion between a compact storage configuration and a stable deployed configuration.
US10299873B2 Surgical instrument driving mechanism
A robotic surgical instrument comprising a shaft, an articulation attached to the distal end of the shaft, and a driving mechanism at the proximal end of the shaft. The articulation comprises a plurality of joints for articulating an end effector, the plurality of joints driveable by at least first and second pairs of driving elements. The driving mechanism comprises a pulley arrangement and a pulley drive. The pulley arrangement comprises first and second pulleys attached together such that their separation is fixed, wherein the first pair of driving elements is constrained to move around the first pulley, and the second pair of driving elements is constrained to move around the second pulley. The pulley drive is configured to linearly displace the pulley arrangement, such that a linear displacement in one direction away from the distal end of the shaft causes the first pair of driving elements to be tensioned and the second pair of driving elements to be de-tensioned, and a linear displacement in an opposing direction towards the distal end of the shaft causes the second pair of driving elements to be tensioned and the first pair of driving elements to be de-tensioned.
US10299871B2 Automated system and method for hair removal
Automated systems and methods for removing hair from a body surface is provided. The methods and systems are semi- or fully automated. Some of the steps of the methods comprise determining a hair growth phase and selecting hair follicles for depilation based at least in part of the identified hair growth phase. The energy delivery device may be attached to the robotic arm and directed to align with the hair follicle to be depilated.
US10299869B2 Input device assemblies for robotic surgical systems
A reaction torque transducer for mounting a motor of an instrument drive unit includes a motor plate, a mounting plate, and a flex ring. The motor plate is fixed to the motor and the mounting plate is fixed to a fixed structure. The flex ring is positioned between the motor plate and the mounting plate. The flex ring includes a body having a first end and a second end that are moveable relative to one another. The first end of the body is fixed to the motor plate and the second end of the body is fixed to the mounting plate. The body is configured to flex in response to the first and second ends moving with respect to one another. A strain gauge is positioned on the body of the flex ring and is configured to measure flexation of the body.
US10299868B2 Robot arm apparatus, robot arm control method, and program
A medical support arm apparatus including: an arm unit including a plurality of links joined to each other by one or a plurality of a joint unit; and a driving control unit that drives the arm unit by controlling driving of the joint unit. If a malfunction is detected in at least one of the joint unit, the driving control unit controls the driving of the joint unit in a state in which a certain restriction is imposed on motion of the arm unit, and drives the arm unit to avoid the malfunction.
US10299866B2 Multiple-joint input arm for control of a surgical mechanical arm
A surgical system for control of a surgical mechanical arm, which system comprises: at least one input arm comprising: a plurality of sections; a plurality of joints sequentially coupling said plurality of sections; at least one sensor configured to measure movement of one or more of said sections; and a weight attached to one of said plurality of sections which biases said one of said plurality of sections to a null configuration, by movement under gravity of said one of said plurality of sections about one or more of said joints; and circuitry configured to receive a measurement signal from said at least one sensor and to generate a control signal, based on said measurement signal for control of movement of said surgical mechanical arm.
US10299865B2 3D system and method for guiding objects
A method for providing a guided relative movement of a first object and a second object includes obtaining the first object; obtaining the second object and a 3D model of the second object, and deriving from the 3D model a first preferred relative arrangement between the first and second objects; obtaining a pre-process plan describing a preferred path for the relative movement of the first and second objects towards the first preferred relative arrangement; performing a movement procedure that includes 3D scanning at least a region of said second object using the 3D scanner and determining a present relative arrangement of the first and second objects from a result of the 3D scanning; calculating information for correcting in real-time for deviation in the relative movement from the preferred path; and providing a relative movement of the first and second objects towards the first preferred relative arrangement.
US10299861B2 Basket and everting balloon with simplified design and control
Disclosed systems, methods, and devices may include a system for removing a kidney stone from a ureter. The system may have an inner shaft extending coaxially within an outer shaft, a stone retention member shaft having a stone retention member and extending coaxially within the inner shaft, a wall protection member coupled to the outer shaft and the inner shaft, and a handle coupled with proximal ends of the outer shaft, the inner shaft, and the stone retention member shaft. The handle may include an eversion mechanism coupled to the inner shaft and configured to actuate the inner shaft, thereby everting the wall protection member to form a pocket adapted to receive a kidney stone. The system may also include a retention member mechanism coupled to the stone retention member shaft and configured to actuate the stone retention member shaft.
US10299856B2 Systems and methods for performing endometrial ablation
A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. If it is determined that the uterus is not perforated, a patency test can be performed to determine that the uterine device is not clogged or embedded in tissue. If the uterus is intact and the device is not clogged or embedded in tissue, the uterus can be treated with the uterine device, e.g., uterine ablation. Systems for performing these methods are also disclosed.
US10299853B2 Electrosurgical forceps
An electrosurgical forceps includes a housing having a shaft extending distally therefrom. The shaft defines a longitudinal axis therethrough and a knife blade shaft is operably disposed within the shaft. An end effector is operably disposed at a distal end of the shaft. The end effector includes a pair of spaced-apart first and second jaw members that are movable from an open configuration to a clamping configuration. An electrode assembly includes first and second electrode housings and a knife blade. The first and second electrode housings are operably coupled to one another and are configured to selectively couple to respective first and second jaw members to electrosurgically treat tissue clamped between the first and second jaw members. The knife blade is configured to selectively couple to the knife blade shaft.
US10299851B2 Dissection scissors on surgical device
A surgical instrument includes an end effector and a housing mechanically coupled to the end effector. The end effector includes a first actuating device configured to perform a first surgical procedure and a second actuating device integrally associated with the first actuating device and configured to perform a second surgical procedure, the second surgical procedure being independently operable and different than the first surgical procedure. An outer portion of the first actuating device and an outer portion of the second actuating device form a portion of an outer housing of the end effector. The housing includes a first actuator, mechanically coupled to the first actuating device and configured to impart movement to the first actuating device and a second actuator, mechanically coupled to the second actuating device and configured to impart movement to the second actuating device.
US10299847B2 Systems and methods for intramedullary nail implantation
Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail. In some embodiments, the proximal end may further include a cross-locking feature, which includes a second bone anchor that interlocks with a first bone anchor, for example, for enhanced bone purchase and bony fixation.
US10299844B2 Osteosynthesis screw with reduced radial compression
The invention concerns an osteosynthesis screw (1) formed from a core (2) externally provided with a helical thread (3), said screw comprising a distal penetration portion and a proximal portion forming the head of the screw (6) and having a conical longitudinal section characterized in that the proximal portion comprises annular notches which are formed in the thickness of the core (2) and in the gaps between the threads of said proximal portion in such a way as to reduce the radial pressure during screwing.—Surgical device.
US10299842B2 Bone plates with dynamic elements
Bone fixation systems include various combinations of stabilizing members, dynamic elements, fasteners, and locking mechanisms. Bone plates receive dynamic bone staples and bone screws. Other dynamic elements include elbow pegs, straight pegs, and wire pegs.
US10299839B2 Percutaneous access devices and bone anchor assemblies
A percutaneous access device includes an inner tube and an outer tube disposed about at least a portion of the inner tube. The outer tube may be sized to span from a skin incision in a patient to a site proximate the spine of the patient. The distal end of the outer tube may be adapted to releasably engage a bone anchor. The inner tube may be adjustable relative to the outer tube between a first position and a second position in which the distal end of the inner tube contacts the bone anchor. A bone anchor assembly includes a bone anchor having a distal bone engaging portion and a receiving member having a recess for receiving a spinal fixation element. The proximal end of the receiving member may have an arcuate groove formed on an exterior surface thereof to facilitate connection of an instrument to the receiving member.
US10299836B2 Bottom loaded pedicle screw
A pedicle screw includes a tulip head, a rod seat, a screw shank, and a retainer collar. The tulip head has an upper opening disposed in a top end of the tulip head and a lower opening disposed in a bottom end of the tulip head opposite the upper opening. The upper and lower openings form a single cavity extending through the tulip head from a top end to the bottom end. The rod seat is disposed within the cavity of the tulip head and engages a stop extending inwardly from an interior wall of the cavity. The screw shank has a thread disposed along a length of the screw shank and a connector positioned at an upper end. The retainer collar has a pass through aperture, an expansion slit, and is disposed about the connector of the screw shank. Other embodiments are described and claimed.
US10299834B2 Polyaxial screw
The present invention generally is directed toward a spinal fixation system whereby a coupling element allows the physician to selectively lock or unlock either the connection between the coupling element and a fastener, such as to allow for repositioning of the coupling element, or the connection between the coupling element and an elongate rod. The locking or unlocking of these connections may be made independently and as desired by the physician.
US10299833B2 Splay control closure for open bone anchor
Open implant closure structures include a helically wound guide and advancement flange form having splay control surfaces. Multi-start closures and closures with inner set screws have splay control contours for interlocking with cooperating flange forms of bone anchor receivers. Flange form heights, thicknesses and other geometry, such as splay control ramp angle may be varied.
US10299829B2 Tissue repair system
An apparatus for repairing an anatomical tear, such as a tear in the meniscus of a human knee. The apparatus includes a guide cannula directing a penetrating shaft through the meniscal tear and through the outer skin layer of the knee. The penetrating shaft pulls a line to the outside of the skin layer of the knee where it is used to pull or kedge a repair implant into position across the meniscal tear.
US10299826B2 Needle for invasive medical use and needle assembly
A needle for invasive medical use includes a long extended cylindrical needle shaft having an axis and an outer surface area, with a short shaft end at a first end of the shaft with a beveled tip with a pointed end, and a needle hub attached to a second end of the shaft including a device to indicate the location of the shaft end during use inside a body. The needle has a flexible joint with a notch within the shaft at the beginning of the shaft end. The device is a displacement sensor for detecting a displacement of the shaft end relative to the rest of the shaft resulted from a force applied to the shaft end when the needle hub is moved and a signal conductor to transmit the detected signals. The invention further describes a needle assembly comprising such a needle and a syringe attached to said needle hub, whereas an evaluation unit is connected to the signal conductor.
US10299823B2 Scoring balloon catheter
A scoring balloon catheter includes a scoring balloon, a distal control balloon positioned distal of the scoring balloon, a proximal control balloon positioned proximal of the scoring balloon, and a scoring element coupled to the proximal and distal control balloons. The scoring balloon is configured to expand radially and contact the scoring element.
US10299822B1 Double bladed surgical tool in combination with a targeting guide
An apparatus for creating minimal skin incisions and soft tissue tunnels, particularly useful in the insertion of transverse or oblique screws through a bone and the holes in a locking nail embedded within the intra-medullary cavity of the bone. A unique surgical tool, as described herein, is used in conjunction with a targeting guide and targeting guide tunnel to create skin and soft-tissue tunnels that are precise, of minimal size, and minimally traumatic for the patient, and very quick and easy for the surgeon to create and to repair.
US10299819B2 Reciprocating rotary surgical cutting device and system for tissue resecting, and method for its use
An endoscopic tissue resecting system that includes a reciprocating rotary surgical instrument for cutting tissue that includes a planetary gear assembly to vary rotational speed. A method of cutting and detaching tissue includes positioning an outer member such that tissue is located within a window in the outer member, engaging the tissue with an inner member, and simultaneously rotating at an increased speed relative to a rotary driver and translating the inner member to cut the tissue. A tangential cutting force is applied to the tissue with the inner member to mechanically cut and detach the tissue.
US10299817B2 Motor-driven fastening assembly
In various embodiments, a fastening assembly comprising a first jaw, a second jaw, a closure member, a rotatable drive shaft, a firing member, an electric motor, a sensing device, and a control system is disclosed. The second jaw is movable between an open position and a closed position relative to the first jaw. The closure member is movable between a first position and a second position. The second jaw is in the closed position when the closure member is in the second position. The electric motor is operable to rotate the rotatable drive shaft and advance the firing member through a firing stroke. The sensing device is configured to sense when the closure member is in the second position. The control system is configured to prevent advancement of the firing member through the firing stroke until after the second jaw is in the closed position.
US10299814B2 Flexible transoral endoscopic gastroesophageal flap valve restoration device and method
A transoral gastroesophageal flap valve restoration device has sufficient flexibility and dimension to be passed through the mouth, throat, and esophagus of a patient into the patient's stomach. The device includes a first member and a second member hingedly coupled to the first member. The first and second members are configured to flex in a direction to follow the esophageal path into the stomach and to be substantially rigid when forming the restored gastroesophageal flap valve.
US10299813B2 Surgical apparatus for endoscopic inferior turbinate lateralization
A surgical apparatus is provided for performing turbinate lateralization including a pair of levers connected at a fulcrum, each lever including a handle connected to a bend portion, a pair of shafts, each shaft connected to the bend portion of each of the levers on first side of the fulcrum, where each shaft is dilated laterally with a substantially parallel displacement along a shaft length in response to the pair of levers being brought together on a second side of the fulcrum; a limiter connected to the pair of levers and configured to limit a dilation of the pair of levers in response to the pair of levers being brought together on the second side of the fulcrum; and a limiting bridge configured to attach between the shafts at a predetermined distance from the distal end of each shaft and press against a columella of the patient.
US10299812B2 Medical device snare
According to one example a medical device snare is described that may comprise a first strip and a second strip, each having an interlock feature. The first interlock feature configured as a groove and the second interlock feature configured as a rail may be interlocked such that the first strip and the second strip are slidable parallel to one another so a snare portion may form a loop.
US10299811B2 Clot retrieval device for removing clot from a blood vessel
A clot retrieval device (9501) for removing clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.
US10299809B2 Method for reducing biofilm formation
A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.
US10299807B2 Method and apparatus for determining acetabular component positioning
An instrument for establishing orientation of a pelvic prosthesis comprises a tripod having an angularly adjustable guide rod on it. The tips of the legs define a plane, and the guide rod is set by the surgeon to a defined orientation with respect to this plane on the basis of preoperative studies. In use, two of the legs of the instrument are positioned by the surgeon at defined anatomical locations on the pelvis (e.g., a point in the region of the posterior/inferior acetabulum and a point on the anterior superior iliac spine). The third leg then lands on the pelvis at a point determined by the position of the first two points, as well as by the separations between the third leg and the other two legs. The position of the guide rod then defines with respect to the actual pelvis the direction for insertion of a prosthesis.
US10299806B2 Bone clamp
A bone clamp having a first jaw, an opposed second jaw and a drill guide, the drill guide being attached to the first jaw so that bone held between the first jaw and the second jaw can be drilled by a drill inserted through the drill guide, the first jaw having a longitudinal axis. The drill guide can be ball shaped at one distal end thereof that is positioned sufficiently within and retained within a corresponding cavity of the first jaw so that the angle of the drill guide can be adjusted to compound angles in the longitudinal and transverse directions in relation to the longitudinal axis of the first jaw. The bone clamp preferably comprises an organic polymer that is relatively transparent to X-rays.
US10299805B2 Systems for treating a vertebral body
Methods and devices that displace bone or other hard tissue to create a cavity in the tissue. Where such methods and devices rely on a driving mechanism for providing moving of the device to form a profile that improves displacement of the tissue. These methods and devices also allow for creating a path or cavity in bone for insertion of bone cement or other filler to treat a fracture or other condition in the bone. The features relating to the methods and devices described herein can be applied in any region of bone or hard tissue where the tissue or bone is displaced to define a bore or cavity instead of being extracted from the body such as during a drilling or ablation procedure.
US10299801B2 Distal femoral jig assembly
A cutting apparatus for resecting a distal face of a femur prior to implanting a femoral component of a total knee prosthesis, comprises an elongate rod adapted for inserting into an intramedullary canal of the femur, a distal femoral cutting block, and a distal femoral jig assembly. The jig assembly can position the distal femoral cutting block on either left leg or right leg. It includes a distal femoral jig having at least one passage for slidingly receiving the rod with a preset valgus angle and a distal end face being adapted for abutting against on the distal face of the femur of either left leg or right leg dependent on its two flip orientations.
US10299800B2 Surgical instrumentation and methods of use for implanting a prosthesis
In one embodiment, the present invention includes a method of alignment for resection of tissue including obtaining a surgical device comprising an alignment guide, a first guide structure and a second guide structure; securing the alignment guide to a bone, the alignment guide including a positioning block; placing the first guide structure onto the positioning block of the alignment guide; viewing a target location of a first resection plane on the bone using the first guide structure; adjusting the target location of the first resection plane by adjusting a position of the first guide structure; attaching the second guide structure to the first guide structure; viewing a target location of a second resection plane on the bone using the second guide structure; and adjusting the target location of the second resection plane by adjusting a position of the second guide structure.
US10299799B1 Micro-macro endovascular occlusion device and methodology
A vascular plug comprises a superstructure expandable from a collapsed percutaneous insertion configuration to an expanded deployment or use configuration. The superstructure is comprised of both primary and secondary three-dimensional shapes allowing for the occlusion of a wide range of vessel sizes from small to large through a disproportionately small delivery catheter. The plug includes a shape memory element for the generation of radial force and the creation of the larger secondary three-dimensional twisting or helical superstructure as is needed for target vessel occlusion.
US10299798B2 Packing coil
An occlusion device formed of a microcoil having a three-dimensional relaxed state employing open looped portions interposed between closed loop portions. Planes defined by sequentially formed open looped and closed loop portions are neither coincident nor parallel to one another.
US10299797B2 Occlusion device and methods of using the same
An occlusion device for occluding a body vessel and methods of using the device are disclosed.
US10299796B2 Endoscopic plication devices and methods
Described herein are endoscopic plicators passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed plicators allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver sutures, staples or other means for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications is formed, medical devices may be coupled to the plication(s) for retention within the stomach.
US10299795B2 Devices and methods for esophageal lengthening and anastomosis formation
Devices and methods can be used to treat long gap esophageal atresia, while obviating much of the delay and complexities associated with current procedures. The devices and methods involve actively stretching the esophagus portions with traction to promote growth of the esophagus portions. Moreover, the devices and methods provided allow for a compression anastomosis to occur between the esophageal ends. This eliminates the need for a second operation to suture the esophageal ends together.
US10299790B2 Adapter with centering mechanism for articulation joint
A joint assembly of an adapter defines a first longitudinal axis and includes first and second hinges, first and second rings, a joint cover, and a biasing mechanism. The joint cover has first and second cover portions. The first ring is pivotally coupled to the first hinge and the first cover portion is pivotally coupled to the first hinge to define a first joint center. The second ring is pivotally coupled to the second cover portion and the second hinge is pivotally coupled to the second ring to define a second joint center that is spaced from the first joint center. The first and second joint centers define a cover axis of the joint cover. The biasing mechanism is engaged with the first ring and the joint cover to bias the joint cover towards an aligned configuration in which the cover axis is aligned with the first longitudinal axis.
US10299782B2 Meniscal repair devices, systems, and methods
Meniscal repair devices, systems, and methods are provided.
US10299780B2 Apparatus and method for manipulating or retracting tissue and anatomical structure
Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes.
US10299774B2 Dual insufflation and wound closure methods
A dual functioning instrument set, comprising a needle and guide, has not only the capabilities to enter and insufflate the abdominal cavity but also the ability of a suture passer to carry and retrieve suture for closure of the incision sites at the end of the procedure. The needle contains a deployable snare that is used to pass and retrieve suture. The guide is used to repeatedly locate the needle relative to the inner abdominal wall allowing for consistent placement of sutures. For insufflation purposes, obturator tips having different distal structures are provided for shielding the sharp needle tip after insertion through a body wall.
US10299771B2 Minimally invasive surgical devices and methods
Surgical tools for use during scarless or near scarless surgical procedures. At least some of the surgical tools can include a handle portion and a working end removably connected to the handle portion.
US10299770B2 Endoscopic vessel harvesting system components
Components for an endoscopic vessel harvesting system include a vessel dissector and a vessel harvester. In this case, a vessel dissector is provided that is used in conjunction with an endoscope, and comprises: an elongated cannula including a lumen therein for receiving the endoscope; a blunt dissecting tip provided on a distal end of the elongated cannula that permits an operator of the vessel dissector to dissect tissue while viewing internal body structures via an objective lens of the endoscope; and a vessel severing tool extending through at least a portion of the elongated cannula, wherein the vessel severing tool is capable of translating longitudinally relative to the elongated cannula, and wherein the vessel severing tool comprises an electrode-carrying member that is capable of translating circumferentially within an arcuate slot extending through an outer surface of the vessel dissector.
US10299768B2 Biopsy sampler and sample collector
A biopsy sampler comprising a penetration zone for receiving a part of an organism, a ram actuated to move along a path between a withdrawn position and an advanced position, a sample collector that cuts a biopsy sample from tissue in the penetration zone, and a container that receives the sample collector, the sample collector and the container being initially located on opposite sides of the penetration zone, a disposable shield initially located between the ram in the withdrawn position and the penetration zone, advance action of the ram to the advanced position bringing together the sample collector and container, and bringing the disposable shield into the penetration zone, withdrawal action of the ram to the withdrawn position withdrawing the disposable shield, leaving the tissue free to leave the penetration zone, such that in use in collecting a sample the shield contacts tissue surfaces and while the ram does not.
US10299767B2 Sample collection apparatus
The present disclosure describes a sample collection apparatus for collection of biological samples, such as fecal material. The sample collection apparatus includes at least one coupling mechanism to couple a sample collection device to a cap, and includes at least one release mechanism to release at least a part of the sample collection device from the cap. The sample collection device in a first configuration is coupled to the cap and in a second configuration is displaced from the cap.
US10299763B2 Ultrasound imaging apparatus and method of controlling the same
Disclosed herein is an ultrasound imaging apparatus for dividing obtained ultrasound image information into pieces of image information in units of regions of a human body, mapping a body marker to the pieces of image information corresponding to the body marker, and outputting a result of mapping the body marker to the pieces of image information; and a method of controlling the same. The ultrasound imaging apparatus includes an image processor configured to obtain image information from an object, a controller configured to divide the obtained image information into pieces of image information in units of regions of a human body and map a body marker to the pieces of image information corresponding to the body marker, and a user interface unit configured to output a result of mapping the body marker to the pieces of image information.
US10299761B2 Biopsy probe mechanism having multiple echogenic features
A biopsy probe mechanism and method includes an elongate sample receiving member having a longitudinal axis and having a sample receiving notch. The elongate sample receiving member and a cutting cannula are movable relative to one another along a longitudinal axis. A first echogenic feature and a third echogenic feature are established on the elongate sample receiving member and a second echogenic feature and a fourth echogenic feature are established on the cutting cannula. The elongate sample receiving member and the cutting cannula have a first position in which the first echogenic feature is in longitudinal alignment with the second echogenic feature, and in which the third echogenic feature is in longitudinal alignment with the fourth echogenic feature.
US10299760B2 Ultrasonic imaging system with body marker annotations and method of use
An ultrasonic diagnostic imaging system is operated to acquire an ultrasound image of a region of the body containing suspect anatomy such as a suspected lesion. A body marker template of the region of the body is displayed on a touchscreen display of the imaging system. The operator records the location of the suspect anatomy by touching a corresponding point on the body marker template displayed on the touchscreen display. The mark on the template can be finely adjusted by one or more controls on the imaging system control panel. The body marker template can also record a graphic indicating the orientation of the ultrasound probe relative to the body when the suspect anatomy was imaged. A report generator produces a report containing both the ultrasound image of the suspect anatomy and the body marker template with the indicated location of the suspect anatomy.
US10299759B2 Ultrasound system control panel and display lift
The control panel and display of a cart-borne ultrasound system are support by a lift which can be controlled to allow the control panel and display to be raised, lowered, and rotated. The lift has a first pivot elbow mounted to the ultrasound system cart and a second pivot elbow on which the control panel and display are mounted. A four-bar linkage is coupled between the pivot elbows which enables to control panel and display to be raised and lowered while maintaining the inclination of the control panel. The pivot elbows allow the control panel and display to be turned and rotated. A pair of hydraulic struts are mounted to the four-bar linkage to support the weight of the control panel and display. When a control button on the handle of the control panel is depressed the control panel and display can be freely raised, lowered and rotated. When the control button is released the pivot elbows and four-bar linkages are locked in their current positions.
US10299757B2 Medical tube, catheter, and method for producing medical tube
A first tube is a medical tube provided with a first portion, a second portion and a third portion in this order from the proximal end side toward the distal end side and is made of a resin. At the second portion, the outer diameter is smaller than the outer diameter of the first portion and the inner diameter is substantially equal to the inner diameter of the first portion. At the third portion, the outer diameter and the inner diameter are respectively smaller than the outer diameter and the inner diameter of the second portion. In this manner, a medical tube in which the outer diameter of the proximal end side is relatively large and the outer diameter of the distal end side is relatively small while securing the inner diameter having a sufficient size at the distal end side can be provided.
US10299752B2 Medical image processing apparatus, X-ray CT apparatus, and image processing method
A medical image processing apparatus according to an embodiment includes storage circuitry, image data processing circuitry, and association circuitry. The storage circuitry stores therein pieces of image data on a subject obtained at a plurality of time phases from a medical image diagnostic apparatus. The image data processing circuitry calculates an index value obtained by comparing a pixel value of image data of a reference time phase among the pieces of image data of the time phases and a pixel value of each of the pieces of image data of the time phases. The association circuitry selects at least one of the pieces of image data of the time phases based on the index value calculated for each of the time phases and associates the one piece of image data with a breathing time phase in at least one of inspiration and expiration of the subject.
US10299749B2 Mammography device, radiographic imaging method, and program
An irradiation condition setting section 52 sets irradiation conditions corresponding to the emission angle of radiation emitted from a radiation source 26. The radiation source 26 emits radiation to a breast at a plurality of different emission angles based on the set irradiation conditions. A radiation detector 36 generates a plurality of projection images corresponding to the plurality of emission angles. An image correction section 56 corrects each projection image such that a difference between at least either contrasts or density values in the plurality of projection images is reduced. A reconstruction unit 58 reconstructs a tomographic image based on the plurality of corrected projection images.
US10299747B2 Device having a C-arm and X-ray imager
The disclosure provides a device having a C-arm, the C-arm including a main body of which the cross-sectional profile is formed as a double H, an outer wall, an inner wall and two side walls of the main body forming a rectangular cavity. The device also includes running wires arranged on the main body and running rollers, on which the C-arm is movably mounted, rolling on the running wires. The running wires and the running rollers are arranged in such a way that at least 50 percent of the mounting forces acting on the running wires due to the running rollers is introduced into the side walls of the main body. The disclosure also provides an x-ray imager having such a device. The disclosure offers the advantage that undesired oscillations of the C-arm are avoided.
US10299746B2 Radiation imaging apparatus
A radiation imaging apparatus provided with a detector capable of improving correction accuracy at a high counting rate. The present invention is provided with: grids that remove scattered beams that emanate from an object; and a plurality of detector sub-pixels arranged so as to divide the gap between the grids into three or more segments, wherein the area of each of the detector sub-pixels located below the wall surface of the grids is larger than that of each of the other detector sub-pixels in a planar view. The size of each of the detector sub-pixels not located below the wall surface of the grids is expressed as (Pg−Tg−Lsplit×2)/N, where Pg represents the pitch between the grids, Tg represents the thickness of each of the grids, and N represents the number of segments formed by the detector sub-pixels between the grids.
US10299742B2 Multiple-dimension imaging sensor with fault condition detection
Methods and systems are described for operating an imaging system that includes an intra-oral imaging sensor, an image sensing component, a multi-dimensional sensor, and an electronic processor. The intra-oral imaging sensor includes a housing and the image sensor component and the multi-dimensional sensor are at least partially housed within the housing. The multi-dimensional sensor includes a three-dimensional accelerometer, a three-dimensional gyroscope, and a three-dimensional magnetometer. The electronic processor is configured to execute one or more error condition check routines to determine whether an error condition is present based on an output received from the multi-dimensional sensor.
US10299729B2 Heart rate detection with multi-use capacitive touch sensors
This document describes heart rate detection with multi-use capacitive touch sensors. Fluctuations in capacitance are detected (802) using capacitive touch sensors. These capacitive touch sensors are also used to detect touch inputs to control operations of a computing device. When contact of a person's hand with the computing device is detected, the capacitive touch sensors produce raw capacitance data that indicates detected capacitance fluctuations. The raw capacitance data is extracted (902) from the capacitive touch sensors using a modified device driver that bypasses default driver configurations that ignore fluctuations in capacitance due to heartbeats. Times during which the person's hand contacts the computing device and locations of the contact are determined (804) from the raw capacitance data indicative of the fluctuations. The extracted raw capacitance data is then processed to determine the person's heart rate (806, 808).
US10299728B2 Methods and systems for automatically identifying detection parameters for an implantable medical device
An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spike activity, and power changes in the sensed signals, etc. A detection tool may be selected, and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.
US10299727B2 Coronary sinus inspiration catheter
The present invention provides a coronary sinus inspiration catheter comprising a catheter head section and an extension tube, which are hollow tubular structures, the catheter head section and a distal section of the extension tube are substantially arc-shaped, the catheter head section comprises an arc section and a bend section, and its length is about 4-10 cm, the distal end is small (3-6 F) and the tube diameter of the catheter head section increase gradually toward the proximal end (6-12 F), the catheter head section is bent at a 15-45° angle at the position which has a distance of 0.5-1.5 cm from the distal end, the bend section is a straight or slightly arc-shaped structure. The catheter head section is provided with an end hole and a plurality of side holes, and is equidistantly provided with radiopaque markers from the distal end to the proximal end.
US10299725B2 Positioning a wearable device for data collection
Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target.
US10299724B2 Wristwatch including an integrated pulse oximeter or other modules that sense physiological data
A wristwatch includes a case containing electronic components of the wristwatch. An optoelectronic module including at least one light emitting element and at least one light sensing element is disposed within the case or within a fastener for the wristwatch. The optoelectronic module is operable to obtain physiological data of a person wearing the wristwatch by using the light emitting element and the light sensing element.
US10299719B2 Systems and methods for establishing the stiffness of a bone using mechanical response tissue analysis
Parametric model based computer implemented methods for determining the stiffness of a bone, systems for estimating the stiffness of a bone in vivo, and methods for determining the stiffness of a bone. The computer implemented methods include determining a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f) and fitting a parametric mathematical model to Y(f) and to H(f). The systems include a device for measuring the stiffness of the bone in vivo and a data analyzer to determine a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f). The methods for determining the stiffness include fitting a parametric model to stiffness of the skin-bone complex as a function of frequency H(f) and the compliance of the skin-bone complex as a function of frequency Y(f).
US10299717B2 Detecting stress based on thermal measurements of the face
Described herein are systems and methods for detecting a stress level of a user. In one embodiment, a system includes an inward-facing head-mounted thermal camera (CAM) and a computer. CAM takes thermal measurements of a region on a periorbital area (THROI1) of the user. The computer generates feature values based on THROI1, and utilizes a model to detect the stress level based on the feature values. The model was trained based on: previous THROI1 taken while the user was under elevated stress, and other previous THROI1 taken while the user was not under elevated stress. Some embodiments may utilize additional thermal cameras that take thermal measurements of other regions on the face, which may be utilized to detect the stress level.
US10299715B2 Stress monitoring for individuals in moving structures
Method and device for monitoring stress of an individual in a moving structure by estimating and monitoring a mental component of a total heart rate of the individual, wherein the total heart rate comprises the mental component, a mechanical component, a component relating to heat balance and a component relating to basic metabolic functions, wherein the total heart rate and movements of the individual and the moving structure are measured in real-time, wherein the mechanical component is estimated in real-time based on the real-time movement of the individual and the moving structure, wherein the mental component is obtained by subtracting the mechanical component, the component relating to the heat balance and the component relating to basic metabolic functions from the total heart rate.
US10299710B2 Organism optical measurement device
An organism optical measurement device having a light transmitter/receiver control unit for obtaining measurement data concerning brain activities and a measurement data display control unit for displaying the measurement data. The organism optical measurement device is further provided with a head surface appearance image acquiring unit for acquiring a head surface appearance image of a subject, a head surface appearance image display control unit for displaying the head surface appearance image, and a measurement-related position calculating unit for calculating the measurement-related position in the head surface appearance image from which the measurement data is obtained when an input device specifies the positions in the head surface appearance image corresponding to the positions of a light transmitting probe and a light receiving probe disposed on the head surface of the subject. The measurement data display control unit displays the measurement data in the measurement-related position in the head surface appearance image.
US10299708B1 Multi-stream data collection system for noninvasive measurement of blood constituents
The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
US10299707B2 Compact biosensor of matrix metalloproteinase with cadmium free quantum dots
The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.
US10299704B2 Method for monitoring of activity and fall
A method for monitoring activity of a subject in an environment, comprising providing at least one sensing assembly in the environment of the subject; providing a server communicating with at least one of: i) the subject and ii) the at least one sensing assembly; generating property vectors from data collected by the at least one sensing assembly; characterizing activity of the subject from the property vectors; and having a result of said characterizing step accessible to the server.
US10299703B2 Monitoring a neuromuscular blockade status
The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro-stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.
US10299701B2 On-airway pulmonary function tester
A compact, on-airway, respiratory gas analyzer for performing pulmonary function tests incorporates an IR spectroscopy light guide having a curved, rather than linear, sample chamber that lies transverse to a direction of respiratory gas flow. Cooperating with the sample chamber is an impact plate that functions to steer respiratory and test gases impinging on the impact plate into the curved sample chamber. A source of IR energy is at one end of the sample chamber and an electro-optical sensor responsive to IR energy is disposed at an opposite end of the chamber. The respiratory gas analyzer also includes gas flow paths and valving for carrying out lung capacity and lung diffusion tests.
US10299700B2 Voice control system for an implant
A system for supplying energy to a medical device implanted in a mammal patient. The system comprises an external energy source adapted to be externally arranged to the patient's body and configured to wirelessly transmit energy for powering the medical device. The system further comprises an internal energy receiver adapted to be implanted in the patient's body and configured to receive energy, transmitted from the external energy source, for supplying energy or control signals to the medical device, and a control unit configured to control the amount of energy received by the internal energy receiver, wherein said control unit is configured to control based on a parameter indicating a characteristic of the medical device or a characteristic of the patient's condition.
US10299699B2 Computerized tomography image correction
Methods, apparatuses and computer program products implement embodiments of the present invention that include receiving, from an imaging system operating in an image coordinate system, a three-dimensional image of a body cavity including open space and body tissue, and receiving, from a medical probe having a location sensor and inserted into the body cavity, a signal indicating a location of a distal tip of the medical probe in a sensor coordinate system. The image coordinate system is registered with the sensor coordinate system so as to identify one or more voxels in the three-dimensional image at the indicated location, and when the identified voxels have density values in the received three-dimensional image that do not correspond to the open space, the density values of the identified voxels are updated to correspond to the open space.
US10299698B2 Systems and methods for registration of a medical device using a reduced search space
A method comprises identifying connected anatomical structures in stored images of a patient anatomy and generating a first three-dimensional model of anatomic passageways including a set of anatomical centerlines of the anatomic passageways, and generating a second three-dimensional model of the anatomic passageways including a plurality of linkage elements each including two base points defining a linkage element centerline spanning a shortest distance between the two base points. The method also comprises receiving tracking data corresponding to a point on an instrument positioned within the connected anatomical structures, matching the point on the instrument to one of the plurality of linkage elements representing one of the connected anatomical structures to locate the instrument relative to the connected anatomical structures in the stored images of the patient anatomy, and updating the matching of the point on the instrument to one of the plurality of linkage elements.
US10299697B2 Microelectrode for measuring EMG of laboratory microfauna and method for manufacturing the same, and system for measuring EMG of laboratory microfauna using microelectrode
The present disclosure relates to a microelectrode for measuring EMG signals of a laboratory microfauna. The present disclosure includes a metal plate with an insulating plate deposited on a surface, a plurality of silicon substrates disposed on the insulating plate, the silicon substrates being electrically connected to the metal plate, covered with an insulator, and adjacent to one another, and a plurality of needle electrodes, each formed on the respective silicon substrates as an integral part thereof, wherein the needle electrodes have the same predetermined length, have a tapered shape from the respective silicon substrates, are spaced apart from each other by a predetermined distance, and wherein a metallic layer is formed on each of the needle electrodes by depositing metal materials, the insulator is formed on the metallic layer, and a portion of the metallic layer at a tip is exposed.
US10299694B1 Method of classifying raw EEG signals
The method of classifying raw EEG signals uses a classification method based on nuclear features extracted as dominant singular values from an EEG signal segment using singular value decomposition (SVD) and a class means-based minimum distance classifier (CMMDC) to classify a patient's EEG signals. From a mean EEG signal, a set of zero-centered EEG signals are calculated, and from the zero-centered EEG signals and a standard deviation of the EEG signals, a unit variance is calculated for each component. Using the standardized component signals a nuclear matrix is calculated, to which singular value decomposition is applied to generate a set of singular values. The CMMDC is applied to class means associated with first and second classes and a nuclear feature vector to classify the patient's EEG signals as belonging in either the first or second class.
US10299692B2 Systems, components, devices and methods for cardiac mapping using numerical reconstruction of cardiac action potentials
Disclosed are various embodiments of invasive and non-invasive systems for electrophysiological mapping of a patient's heart, where cardiac action potentials (APs) on a myocardial surface of a human heart are reconstructed. In one embodiment, the APs are reconstructed using known electrical potentials on the myocardial surface in combination with known geometries of the heart and/or the torso. A mathematical model of cardiac electrical activity may be employed that takes into account homogeneous and isotropic intracellular, extracellular, and human body electrical conductivities.
US10299690B2 Electronic device and method for measuring biometric information
An electronic device for measuring biometric information is provided. The electronic device includes a sensor unit configured to detect an attitude of the electronic device, a biometric information measurement unit configured to detect biometric information on an examinee through a plurality of electrodes formed on at least one surface of the electronic device, a switch unit including a plurality of switches electrically connected to the plurality of electrodes and a controller configured to recognize an array of the plurality of electrodes based on the detected attitude of the electronic device and control the switch unit such that the recognized electrode array corresponds to a preset electrode array.
US10299689B2 System and method of determining a risk score for triage
The present disclosure provides a system and method of determining a risk score for triage. In particular, a system is provided for providing an assessment of risk of a cardiac event for a patient, for example an incoming patient to a hospital emergency department complaining of chest pain. In the disclosure, the system includes an input device for measuring physiological data based vital signs parameter of the patient, a twelve-lead electrocardiogram (ECG) device for establishing an ECG obtained from results of the electrocardiography procedure, and determining an ECG parameter and a heart rate variability (HRV) parameter therefrom. An ensemble-based scoring system is further provided, establishing weighted classifier based on past patient data and where the vital signs parameter, the ECG parameter and the HRV parameter are compared to corresponding weighted classifiers to determine a risk score. A corresponding method to determine a risk score for triage is also provided.
US10299688B2 Multi-vector sensing in cardiac devices with signal combinations
Methods and devices for combining multiple signals from multiple sensing vectors for use in wearable or implantable cardiac devices. Signals from multiple vectors may be combined using weighting factors and/or by conversion to different coordinate systems than the original inputs, which may or may not be normalized to patient anatomy. Signals from multiple sensing vectors may be combined prior to or after several analytical steps or processes including before or after filtering, and before or after cardiac cycle detection. Cardiac cycle detection information may be combined across multiple sensing vectors before or after analysis of individual vectors for noise or overdetection. Cardiac cycle detection information may also be combined across multiple sensing vectors to identify noise and/or overdetection.
US10299683B2 System and method for differentiation of normal myocardium from diffuse disease using T1 mapping in non-ischemic cardiomyopathies and others
A method for differentiation of normal myocardium from diffuse disease using T mapping includes acquiring one or more images of a patient by an imaging apparatus, generating a T1 map from the one or more images, defining a region of interest within the one or more images, determining the average T1 value within the region of interest, comparing the average T1 value within the region of interest to a cut-off T1 value, and determining a diagnosis of the region of interest from the comparison.
US10299681B2 Implantable medical device system with lead conductor antenna and filter
The invention relates to an implantable medical device system comprising an active medical device having or connected to at least one electrode and circuitry connected to the electrode. The active medical device comprises a telemetry unit. The circuitry connected to the electrode comprises at least one single conductor that provides a radio frequency antenna for the telemetry unit. The implantable medical device system further comprises at least one electronic filter that is arranged between the single conductor of circuitry connected to the electrode and the telemetry unit. The least one electronic filter comprises at least one inductor having a core that comprises a ferromagnetic material with saturating behavior when exposed to an external magnetic field.
US10299673B2 Method and system of enhancing ganglion cell function to improve physical performance
A method and a system of enhancing ganglion cell function using a gaming environment corresponding to a physical activity. The method and system may be used to implement one or more processes to improve a person's visual processing profile. In particular, the method and system may be used to improve a player's skill in the corresponding physical activity.
US10299672B2 Subjective optometric apparatus
A subjective optometric apparatus includes: a projection optical system that includes a target presenting unit configured to emit a target light flux, the projection optical system being configured to project, onto an examinee's eye, the target light flux emitted from the target presenting unit; a housing configured to accommodate the projection optical system; a presentation window configured to project the target light flux onto the examinee's eye by transmitting the target light flux emitted from the projection optical system and outputting the target light flux from an inside of the housing to an outside of the housing; and an observation unit configured to observe, via the presentation window, a positional relationship between the examinee's eye and an eye refractivity measuring unit configured to change an optical property of the target light flux output from the inside of the housing to the outside of the housing.
US10299669B2 Light-guided joint access
A method for accessing the interior of a joint, wherein the joint comprises tissue which defines a boundary of the joint, the tissue comprising an interior surface facing toward the interior of the joint and an exterior surface facing away from the interior of the joint, the method comprising: providing a light-emitting needle assembly comprising a hollow needle having a light source at the distal end thereof; and observing the interior surface of the tissue from the interior of the joint as the needle approaches the exterior surface of the tissue.
US10299668B2 Laryngoscope with handle-grip activated recording
Disclosed are embodiments of a laryngoscope that facilitates targeted recording (video, or audio, or both video and audio) of time intervals associated with active laryngoscopy. In accordance with the teachings of the disclosure, a characteristic that reliably defines the interval of active laryngoscopy is used to trigger recording. One such characteristic is that the operator's hand is gripping the handle of the laryngoscope. Accordingly, preferred embodiments implement a laryngoscope having a handle so designed that when the handle is gripped by the operator's hand, recording is initiated and continued for as long as the operator's hand maintains a grip on the laryngoscope handle.
US10299666B2 Endoscope system
An endoscope system is provided by which observation image brightness can be suppressed from irregularly fluctuating before and after changing of an observation mode and observer's discomfort feeling can be reduced. The endoscope system includes an imaging element, an image processing section that generates an observation image from an imaging signal, a display section that displays the observation image, an illumination mode changing section that changes illumination modes of a light source device, an image processing mode changing section that changes an image processing mode, and a light source control section that controls the light source device.
US10299664B2 Solid-state imaging device and endoscope system
The solid-state imaging device includes a semiconductor layer, an electrode, a wiring layer, a plurality of filters, an input terminal, and a voltage generation circuit. The voltage generation circuit generates a first voltage and a second voltage. The plurality of filters include a first filter and a second filter. The light transmittance of the first filter has a peak in a wavelength range corresponding to blue. The light transmittance of the second filter has a peak at a wavelength of 450 nm or more, and in the second filter, the transmittance of light having a wavelength of 450 nm or less is greater than the minimum value of the transmission of light having a wavelength longer than 450 nm. The first voltage and the second voltage are selectively applied to the electrode.
US10299663B2 Wide-angle illumination device
A wide-angle illumination device includes a base, a first light guiding module and two second light guiding modules. The base includes a central region and two lateral regions, and the two lateral regions are respectively located on opposite positions of the central region. A first light emitting module is disposed on the central region, and two second light emitting modules are disposed on the two lateral regions. The first light guiding module is disposed on the central region and matched with the first light emitting module, to guide a first optical signal of the first light emitting module toward a front of the base. The two second light guiding modules are disposed on the lateral regions and matched with the second light emitting modules, to guide a second optical signal of the second light emitting module out of an end of the base.
US10299656B2 Vent outlet for appliance having adjustable kickplate
A vent outlet for an appliance having an adjustable kick plate configured to enclose a base portion of the appliance is provided. In an example embodiment, the vent outlet comprises a top portion, a vent cover, a bottom portion, and a conduit portion. The top portion comprises a planar portion and an angled portion. The front surface of the vent cover is coplanar with the front surface of the planar portion. The bottom portion that is recessed with respect to the front surface of vent cover. The planar portion, the vent cover, and the bottom portion are generally aligned along a first axis. The conduit portion extends backward from a plane defined by the vent cover and is configured to secure the vent outlet to a vent conduit of the appliance.
US10299647B2 Vacuum cleaner
A vacuum cleaner including a cleaner body; and a dust collector provided in the cleaner body, wherein the dust collector includes a first cyclone provided within an outer case to filter foreign matter and dust from air introduced into the dust collector; a second cyclone accommodated within the first cyclone to separate fine dust from the air introduced into the first cyclone; and a rotatable shell provided at a lower side of and surrounding the first cyclone so as to define a first storage section configured to collect foreign matter and dust filtered by the first cyclone between the rotatable shell and the outer case, wherein the rotatable shell includes a skirt having a plurality of steps arranged along a circumference of the rotatable shell.
US10299645B2 Vacuum cleaner
A vacuum cleaner, including a cleaner body; and a dust collector provided in the cleaner body, wherein the dust collector includes a first cyclone provided within an outer case to filter foreign matter and dust from air introduced into the dust collector; a second cyclone accommodated within the first cyclone to separate fine dust from the air introduced into the first cyclone; a screw provided at a lower side of and surrounding the first cyclone, and having at least one vane spirally extended along a flow direction of the air introduced into the outer case to induce the inflow of foreign matter and dust filtered by the first cyclone into a first storage section.
US10299641B2 Toilet seat having an automatic cleaning device
A toilet seat (1) with an automatic cleaning device (10), the toilet seat (1) including: a first assembly (2) with a mounting panel (7) that can be secured to a rear section of a lavatory body (8); and a second assembly (3) which includes a lavatory seat ring (9) able to be driven in the peripheral direction, a bearing frame (29) for the lavatory seat ring (9), a drive device (26) for the lavatory seat ring (9), secured to the bearing frame (29), and a cleaning device (10) for the lavatory seat ring (9), likewise secured to said bearing frame (29). The first and second assembly (3) are pivotally interconnected by means of hinge joints (4).
US10299637B2 Toilet-paper-roll holder
A holder (10) for at least two toilet-paper rolls (12, 14) which are arranged one above the other and consist of a paper web (56) wound up on a sleeve (52, 54) or a shaft, having a first and a second wall (28, 30) which are arranged at a distance parallel to each other, wherein each of the walls (28, 30) has a guide (40, 42) for receiving one end each of the shaft or of a shaft journal, which can be received in an opening in the sleeve, wherein the guide (40, 42) has a substantially vertically running supply portion (40b) for supplying a toilet-paper roll (12, 14), the supply portion merging into an unrolling portion (40c) running at an inclination with respect to the vertical in the direction of at least one first tear-off element (60, 62) or a stop (72).
US10299635B2 Pre-formed shower pan systems and methods
A shower pan has a first portion having a drain hole and a bottom flat surface to contact a floor and a top surface having a predetermined slope toward the drain hole; and a second portion coupled to the first portion at the drain hole, the second portion having a bottom surface with the predetermined slope and adapted to gaplessly fit with the first portion through a waterproofing pan liner.
US10299616B1 Zipper assistant device
A zipper assistant device that provides consumers with an accessory to help conveniently zip-up their zippers which are often located on the back of clothing. The zipper assistant device includes an on and off switch having a casing, an ON button and an OFF button, the casing having a front facing and contains a battery to power the on and off switch, an elongated handle having a first end and a second end, the on and off switch attached to the first end of the elongated handle, a handle base attached to the second end of the elongated handle and a bulb-shaped magnetic field element attached to the handle base opposite the elongated handle.
US10299614B2 Door hook
A door hook includes a top member, a back member, a front member, a hook and a leg. The back member is attached to the first end of the top member and the front member is attached to the opposite end of the top member. The leg and hook are also attached to the front member. The leg extends below the hook. A resilient foot is attached to the leg such that the resilient foot is below the hook. The front member is configured to flex into a generally convex shape after a downward force acts on the hook and the resilient foot is configured to flex after the downward force is exerted on the hook.
US10299613B2 Flexible straw and system and method of manufacturing the same
A corrugating machine for forming a flexible paper drinking straw by forming annular corrugations in a tube, including a plurality of corrugating elements and means for moving the tube against the corrugating elements. Each of the corrugating elements is spaced apart from each other in both a lateral direction and a forward direction. The corrugating machine includes an assembly spool and a drum mounted to a side of the assembly spool for rotation about a common axis. A mandrel is mounted to the drum for reciprocation into and out of the spool assembly, to carry the tube against the corrugating elements mounted in an arc defined about the common axis.
US10299608B1 Child bed fall blocking system
A Child Bed Fall Blocking System is an apparatus that offers safety barriers to prevent small children from falling out of a child's or adult's bed by providing full protection on all 3 exposed sides of the bed. The barriers can be raised and lowered easily to provide easy ingress and egress for adults, and can be collapsed and hidden when not in use. The Child Bed Fall Blocking System that can be installed easily, consists of 4 base plates connected with 3 wires and 2 separate reinforcing wires along the headboard side of the bed, a set of 2 tabs attached to each base plate, 6 vertical height-adjustable telescopic pole sets attached to the base plates, 3 sets of length-adjustable tube sets connecting the inner telescopic poles with hinges, 6 lock systems, and 3 adjustable fabric panels, each secured by a flat bar on the bottom of the panel.
US10299607B2 Convertible high chair
Various embodiments of the present invention are directed to a convertible children's high chair. According to various embodiments, the convertible high chair generally comprises a first child seat supported above a floor by a high chair frame, and a second child seat configured for being removably coupled to first child seat. The second child seat is configured such that, when detached from the high chair's first child seat, it can be used apart from the high chair as a booster seat (e.g., secured to the seating surface of a standard chair or another support surface). In certain embodiments, the second child seat includes a base surface configured to stably support the second child seat on a separate support surface (e.g., without the need to be attached to or mounted on a separate base or support member).
US10299599B2 Collapsible swivel chair
A chair including a swivel assembly. The chair can include three or more arms pivotally connected to the swivel assembly and selectively moveable between an open position and closed position. The chair can also an arm lock disposed on top of the swivel assembly, where the arm lock is selectively moveable between a locked position and unlocked position. The chair can also include a seat removably connected to a distal end of each arm.
US10299598B2 Hub construction for a rotatable chair
The invention relates to a hub construction for a rotatable chair, whereby an uncomplicated and robust plain bearing design is provided. The plain bearing parts are manufactured of metal in such a way that the bearing surface on the underlying pin is softer than that of the overlying sleeve. A plain bearing according to the invention may be provided with an adjustable device for obtaining higher friction and thus an increased rotational resistance. In the upper part of the pin is arranged a horizontal bore, into which is fitted a plug shaped body, the ends of which extend outside the mouths of the bore in the bearing surface as an adjusting screw in the upper end of the pin is tightened against the middle section of the plug-shaped body.
US10299595B2 Chair with articulating backrest
A chair having an articulating backrest that deforms when reclined to support an occupant's head or shoulders. A backrest assembly includes a mesh insert secured to a frame, which includes an upper frame section and a lower frame section interconnected by a pair of articulated joints. A push arm pivotally connects to the chair's seat assembly and to the backrest's upper frame section. As the chair reclines, the push arm restricts the angular movement of the upper frame section relative to a floor. The lower frame section moves forward relative to the upper frame section. Consequently, an angle formed between the lower frame section and the upper frame section decreases during recline, thereby supporting the chair occupant's head or shoulders. Optionally, a tensioning member may connect the mesh insert to the push arm to offset any loss of tension caused by the deformation of the frame during reclined.
US10299591B1 Corner shelf installation tool
Disclosed is a shower corner shelf installation tool that includes a first and second arm that are pivotally connected to one other and are configured to support a shower corner shelf thereon when the shower corner shelf installation tool is in use, the first and second arms each have an upper sidewall connected to a lower sidewall by an outer sidewall positioned there between; anchor members protruding from the outer side wall of each arm that are configured to grip a shower corner to temporarily affix the shower corner shelf installation tool thereto while in use; leveling members extending above the first and second arm that are independently configured to selectively adjust the shower corner shelf during installation; and a tensioning member configured to extend between the first and second arm and apply force to the first and second arms and anchor members while the shower corner shelf installation tool is in use to temporarily affix the shower corner shelf installation tool to shower corner.
US10299587B2 Device and method for fixing a movable furniture part
A device for fixing a push element, in particular a drawer box to a rail of a pull-out guide, the device comprising a clamping mechanism with a receptacle, into which a web-shaped holding part can be inserted, wherein a self-locking clamping element is provided at the receptacle, by means of which the holding part is secured in a clamping manner against being pulled out. As a result, a particularly stable fixation of the drawer box to a pull-out guide can be achieved.
US10299584B2 Adjustable desk
A desk has a base that rests on an underlying floor surface, a work surface that is supported by the base, and a seat that is rotatably connected to the base for rotation between a first position, located in a conventional position behind the desk so a person may sit at the desk, and a second position, located to one side of the desk so that a person may instead stand at the desk. The seat is adjustable radially relative to its axis of rotation, vertically up and down relative to the floor surface, and angularly toward its axis of rotation.
US10299582B2 Accessory cart
In the specification and drawings an accessory cart is described and shown with a base, a housing element that is connected to the base and extends upward from the base, and a platform, which is connected to the housing element with the height of the platform being automatically adjustable.
US10299581B2 Furniture composition with height-adjustable partition
A furniture composition comprises a first workstation having a first worktop adjustable in a vertical direction, a second workstation having a second worktop adjustable, independently of the first worktop, in the vertical direction, and a height-adjustable partition which extends in the vertical direction between the first and second workstation. A first support element is provided on the first worktop, by means of which the partition can be supported in the vertical direction, and a second support element on a second worktop, by means of which the partition can be supported in the vertical direction.
US10299579B2 Oral care implement having collapsible elastomeric element
An oral care implement having a collapsible elastomeric element. The oral care implement may include a body having a handle portion and a head portion. Furthermore, an elastomeric element may extend from the body. The elastomeric element may comprise a hollow body that has an internal cavity, the hollow body having a base section, a middle section, and a distal section that includes a free distal tip, each of the base, middle, and distal sections coupled together by a pre-weakened section. The elastomeric element may be configured to alternate between a collapsed state and a normal state.
US10299578B2 Oral care implement
Disclosed is an oral care implement, comprising: a body comprising a handle and a head at an end of the handle; the body having a cavity therein for storing an oral care fluid; the head having at least one oral care element extending therefrom, and a fluid outlet through which the oral care fluid is dispensable to an exterior of the oral care implement; a passageway fluidly connecting the cavity with the fluid outlet; a mechanism for introducing air into the cavity from the exterior of the oral care implement; and a control valve on the head movable relative to the head between a first position for preventing fluid flow from the cavity through the fluid outlet and a second position for permitting fluid flow from the cavity through the fluid outlet.
US10299577B2 Method for producing brushes, in particular interdental brushes, and brush, in particular interdental brush, and product group comprising a plurality of brushes
The invention relates to a brush, in particular an interdental brush, which comprises a bristle-carrying stem defining a longitudinal direction and having an elongate support core, a bristle area having bristles projecting from the bristle-carrying stem, and a neck element connecting the support core to a handle, wherein the handle, the support core and the neck element are injection molded integrally from a first plastics component, and wherein a second plastics component in the form of an integral layer and the bristles projecting therefrom is mounted on the support core. The invention also relates to corresponding product groups and to a corresponding method.
US10299576B2 Strap for retaining articles
A strap for releasably retaining one or more articles. The strap includes a flexible elongate body and a buckle coupled to the first end. The body has a first region adjacent a first end of the body, a second region adjacent a second end of the body, and a central region positioned between the first and second regions. The central region of the body defines a plurality of spaced apart fastening holes. The first region defines a strap opening for receiving the second end of the strap and releasably engaging a portion of the body. The buckle includes a frame including a proximal region coupled to the first end of the body, a distal region, and first and second side regions between the proximal and distal region. The second side region includes a gateway for releasably receiving any region of the body.
US10299572B2 Pouch or holster coupled with a retracting device
Holstering retractor devices or systems for securing a device or instrument when not in use, such that the instrument does not have to be held or slid into a pocket. The systems are coupled with a retracting device, integrated into the holster, such that if said instrument or device pops out of holster, or is dropped while in use, it is not lost or damaged. The present invention is also directed to systems utilizing the holster retractors, such as vest system having the holster retractor mounted to the vests.
US10299567B2 Mirror with zone of selected magnification and discretionary illumination
A method and a mirror selectively magnify an image reflected by a discrete portion of a reflective area of the mirror while an image reflected by the remainder of the reflective area outside the discrete portion remains unchanged. A light-transmitting area is placed within the reflective area, outside of and adjacent to the discrete portion, and a light source is located for directing light through the light-transmitting area to illuminate a space adjacent to and confronting at least the discrete portion of the reflective area.
US10299566B2 Cosmetic product applicator and associated applicator assembly
An applicator (10) for a cosmetic product has a core (12) and protrusions (20) projecting from the core (12). Each protrusion (20) has a reservoir (21) for the cosmetic product, and a articulation (22) of the reservoir (21) on the core (12). The articulation (22) formed by a narrowed portion. The reservoir (21) extends from the articulation (22) transversely to the articulation (22) and on either side of the articulation (22). An assembly has a receptacle having a body which forms a container intended to hold the cosmetic product. An applicator assembly has a wiper capable of scraping off excess product when the applicator (10) moves from inside the container to outside the container.
US10299563B2 Rotary airless compact
A rotary airless compact including facing concentric arcuate inner and annular outer walls which are manually rotatable relative to each other, and a flexible tube extending between the walls and secured to the inner wall. The outer wall has radial ribs projecting inwardly to crimp the tube at spaced locations against the inner wall, providing successive seals between which the tube has internally open regions for holding fluid product. As the outer wall rotates relative to the inner wall in a direction from a first to a second end of the tube, product is drawn from a supply pouch at the first end into successive open regions of the tube in discrete quantities separated by the seals, and the ribs advance the seals and open regions to the second end, where a nozzle or other dispensing element discharges the quantities of product into a pan area of the compact.
US10299557B2 Lightweight cloth cover suitcase
A lightweight cloth cover suitcase includes a cloth cover, a skeleton including a rectangular metal frame, top and bottom supporting plates respectively mounted at opposing top and bottom sides of the metal frame and adapted to support the top and bottom sides of the cloth cover, a slotted back panel adapted to support the back side of the cloth cover and a honeycomb panel mounted between the bottom supporting plate and the metal frame to enhance the mounting strength of wheel modules that are arranged at the bottom side of the cloth cover.
US10299555B1 Luggage cover
A luggage cover includes a front panel; a back panel; a top panel coupled to the front panel and the back panel; a first side panel coupled to the front panel and the back panel; a second side panel coupled to the front panel and the back panel; a zipping mechanism formed along at least one of the first and second side panels and the top panel; and a plurality of flexible loops, wherein an opening is formed at an opposite side of the top panel to receive a luggage container.
US10299552B2 Collapsible luggage
A collapsible luggage includes a base, a flexible body connected to the base, a telescopic rod unit coupled to the flexible body, and a foldable support coupled to the flexible body, disposed opposite to the telescopic rod unit, and including a first support member that has a buckle member, and a second support member that has a protrusion. When the foldable support is in an unfolded state, the buckle member partially overlaps the protrusion to maintain the foldable support in the unfolded state. When a force is applied to move the foldable support from the unfolded state to the folded state against a resilient force of the buckle member, the buckle member is urged to deform resiliently so the protrusion is permitted to pass over the buckle member.
US10299549B1 Jewelry setting
A jewelry snap setting for supporting a jewel and that includes a one-piece support member having a base portion having multiple sides and a plurality of elongated prongs with one extending from each respective side of the base portion. Each elongated prong includes contiguous respective proximal biasing and distal retaining portions. Each proximal biasing portion extends integrally from a respective side of the base portion, and at least said proximal biasing portion has an arcuate cross-section in a direction that is transverse to the longitudinal axis of the proximal biasing portion.
US10299546B2 Wristbands for securing implements and tools and methods of using
A band adapted for holding implements and tools when the band is secured around a user's arm. The band includes a body delimited by oppositely-disposed longitudinal ends configured to be secured together and by edges that are laterally spaced apart from each other. The edges each have arcuate portions and, upon fastening the longitudinal ends together, the body acquires a circular shape having one axial end that is larger than the other. The band further includes sleeves located on an outer surface of the body and arranged side-by-side so that each sleeve extends laterally across the outer surface, and straps secured to the body and sized to accommodate and secure implements or tools of different sizes. At least some of the straps span one or more of the sleeves, and the straps are disposed at different angles so as not to be parallel to each other.
US10299545B2 Belt adjustment system
Disclosed are belt adjustment systems, particularly for wearing around a user's waist, that permit a continuum of belt loop sizes or a larger selection of belt loop sizes. The belt adjustment system includes an elongate belt member having a first end, a second end and a series of teeth positioned on an inner surface near the second end and a fixation member having first and second adjustment elements.
US10299544B2 Last system for articles with braided components
A last system and a method of making the last system are disclosed. The last system includes a last member and an exterior layer. The exterior layer becomes deformable when heated above a characteristic temperature. The method can include forming a braided footwear component on the last system. The exterior layer may be joined with the braided footwear component by heating the last system above the characteristic temperature.
US10299540B2 Strap systems for articles of footwear and other foot-receiving devices
Strap systems for securing feet into articles of footwear or other foot-receiving devices include one or more strap members formed or engaged together in a continuous path along an upper for an article of footwear or other foot-receiving device. One or more structures for applying a force to the strap member(s) is provided so as to shorten a length of the continuous path and thereby apply tension to the strap member(s). Such strap systems can be arranged so that the strap tightens during plantar flexion or dorsiflexion. Additional aspects of this invention relate to bootie members for supporting such strap systems, upper members or bootie members including such strap systems, and articles of footwear and other foot-receiving devices including such strap systems.
US10299535B2 Sole structure with alternating spring and damping layers
A sole structure may include multiple macrolayers. Each of those macrolayers may include a spring plate and a layer of damping material. Macrolayers may be bonded or otherwise fixed relative to one another and provide constrained layer damping in response to impact forces occurring as a result of activity of a wearer of an article of footwear incorporating the sole structure.
US10299529B2 Helmet comprising surface reinforcing component with embedded anchors
Described herein are helmets comprising at least one surface reinforcing component. In some embodiments the surface reinforcing component comprises at least one anchoring feature embedded in a structural feature of the helmet, such as a force absorbing element. In other embodiments, the surface reinforcing component comprises fasteners configured to mate with a respective fastener on a shell of the helmet.
US10299524B2 Garment having a drawstring closure assembly
A closing and tightening system for the waistband of a garment is provided. Two drawstrings are fed through four grommets. When both strings are pulled tight, both sides of the garment are pulled towards each other, and are secured on top of each other when tied down. The strings are woven through the grommets to allow the garment to be tightened on both sides, creating a secure attachment suited to use on athletic wear.
US10299522B2 Humanized care clothing
A humanized care clothing includes: a coat body, a front body thereof including left and right front side sheets spaced a full open vacancy and a detachable connecting sheet covering the vacancy, two shoulders of the connecting sheet being connectable with or detachable from two shoulder portions of a rear body, and left and right sides thereof the two opposite sides of the left and right front side sheets; a pair of restricting sleeve, two receiving pockets, two limiting pockets, a lower body clothing, the pair of buttoning sleeves being detachable from and connectable with the respective left and right front side sheets, the receiving pocket for each restricting sleeve being sewn below it, the limiting pocket being respectively overlapped with the outer parts of the receiving pockets and capable of connecting the clothing sleeve with the lower body clothing; and a collar member.
US10299519B2 Variable compression garment
Variable compression garments may use an elastomer such as silicone printed on a textile to create a varying amount of compressive force along a limb. Greater amounts of elastomer may be used to create greater amounts of compressive force.
US10299514B2 Heater management
An electrically operated aerosol-generating system may be configured to detect adverse conditions (e.g., a dry heater). The system may comprise an electric heater comprising at least one heating element for heating an aerosol-forming substrate, a power supply, and electric circuitry connected to the electric heater and to the power supply and comprising a memory. The electric circuitry may be configured to measure an initial electrical resistance (R1) of the electric heater; measure a subsequent electrical resistance of the electric heater after the measurement of the initial electrical resistance; determine the difference (ΔR) between the initial electrical resistance and the subsequent electrical resistance; determine that an adverse condition is present if the difference is greater than a maximum threshold value (ΔRmax) or less than a minimum threshold value (ΔRmin) stored in the memory; and control a power to the electric heater and/or provide an indication if the adverse condition is present.
US10299513B2 Disposable tank electronic cigarette, method of manufacture and method of use
An electronic cigarette device having a disposable tank are described. The disposable tank may have a sealed liquid chamber, an atomizer element and a tank well. An electronic cigarette device, comprising: a housing having a power source; a disposable tank capable of holding an electronic cigarette liquid; the housing having a tank receptacle into which the disposable tank is removable attachable; and a connection mechanism that is part of the disposable tank and the tank receptacle that securely connects the disposable tank to the tank receptacle and provides power from the housing to the disposable tank.
US10299506B2 Method for inspecting an elongated element
A method is proposed for inspecting cylinder-shaped elongated elements for smoking articles that provides projecting from a first half-space a first stripe of light onto an external face of a first elongated element and projecting from a second half-space onto the first elongated element a second stripe of light. The method reconstructs, by means of a first identified curved line and a second identified curved line respectively in a first acquired view and in a second acquired view of the first elongated element, a first closed curved section profile of the first elongated element and identifies possible deformations of the reconstructed first closed curved profile with respect to an ideal section profile. The method further includes the step of arranging an ideal elongated element alongside the first elongated element, respectively in a reference position and in a first position, inspecting simultaneously the first elongated element and the ideal elongated element by the first stripe of light and the second stripe of light; reconstructing, by a first identified curved line and a second identified curved line respectively in the first view and in the second view a first closed curved section profile of the ideal elongated element; monitoring the reconstructed closed curved profile of the ideal elongated element generating a warning if the reconstructed closed curved profile of the ideal elongated element is different from an ideal section profile, for example circular.
US10299502B2 Method for producing an extract of a matrix of vegetable origin with a non-ionic amphiphilic compound as extraction adjuvant in an aqueous medium
The invention relates to a method for producing an extract of a matrix of vegetable origin, particularly a plant, involving a solid-liquid extraction by means of an aqueous solution containing at least one, preferably agro-sourced, non-ionic amphiphilic compound, at a concentration at least equal to the minimum hydrotrope concentration thereof.
US10299501B2 Stabilizer composition of microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
The subject matter of this invention is a composition and method of making a water-dispersible, stabilizing colloidal microcrystalline cellulose:carboxymethylcellulose composition. The method of making the composition does not require a salt solution as an anti-slip agent.
US10299497B2 Method for discharge control of a separator
A method for discharge control of a separator including an inlet for a dairy product, a first outlet conduit for a first processed dairy product, and a second outlet conduit for a second dairy product. The first processed dairy product having a higher fat concentration than the second processed dairy product. The method involves detecting a flow rate of the first processed dairy product in the first outlet conduit, controlling the flow rate of the first processed dairy product in the first outlet conduit by regulating an opening degree of a regulating valve connected to the first outlet conduit, detecting the opening degree of the regulating valve, and discharging the separator when the opening degree of the regulating valve exceeds a predetermined value. The invention also relates to a separator for separating a dairy product into a first processed dairy product and a second processed dairy product.
US10299492B2 Dietary supplement compositions with enhanced delivery matrix, gummies, chocolates, atomizers and powders containing same, and methods of making same
A dietary supplement composition having a dispersion including a plurality of liposomal vesicles, includes an active ingredient, phospholipid contained in the liposomal vesicles, and a coating material. The active ingredient is incorporated within the liposomal vesicles having a barrier coating of the coating material including one of a biopolymer, polyethylene glycol, chitosan and a combination thereof. The coating material is free flowing in the dispersion such that the liposomal vesicles are surrounded by the coating material without being attached to the liposomal vesicles and without forming part of the liposomal vesicles and without affecting weight of the liposomal vesicles. The dispersion is filtered using a tangential flow technique, which washes out outer periphery of liposomal vesicles for removing inactive ingredients contained outside the liposomal vesicles without washing out the coating material surrounding the liposomal vesicles. The dietary supplement composition may be incorporated in gummies, chocolates, atomizers or powders.
US10299491B2 Beverage
A method of producing tea syrup comprises contacting a plant material and/or plant extract with hot water to produce a tea. The method comprises filtering the tea to produce a tea filtrate, adding sugar to the tea filtrate, and then reducing the pH of either the tea or the tea filtrate, and thereby producing a tea syrup.
US10299486B2 Portable stunner
A portable pneumatic stunner for stunning or euthanizing an animal has a piston slideable within an inner chamber, a housing with a front portion being moveable toward and away from its rear portion, a stunning rod driven by the piston forward towards the front end of the housing, a catch system for alternately holding and releasing the stunning rod, and a regulator for regulating the pressure received from a fluid container for operating the stunner. The stunning rod is driven along a longitudinal axis upon exposure of a pressurized fluid to the piston, and the stunning rod is retracted back into the stunner after firing by exerting a manual inward force on the stunning rod and housing. The catch system comprises a plurality of arcuate sections substantially forming a cylinder. The regulator determines the allowable pressure levels of the fluid the stunner is subjected to.
US10299485B2 Method for preparing a flour tortilla
The disclosure defined by this invention describes a method for preparing a flour tortilla (including whole wheat or multi grain) which utilizes a fatty substance in the form of a powder, granulate or crystal to improve the properties of the tortilla.
US10299484B2 Composition essentially free of water and comprising at least one spore forming fungal biological control agent, a polyether-modified trisiloxane and fumed or precipitated silica
The present invention relates to a liquid composition comprising at least one biological control agent wherein said biological control agent is spores of a spore forming fungus, a polyether-modified trisiloxane and fumed silica or precipitated silica, wherein said composition is essentially free of water, said composition being useful in plant protection.
US10299481B2 Methods for treating arthropods
Methods for treating arthropods comprising depositing at least one drop of a liquid formulation containing at least one surfactant on a solid surface of an arthropod at a contact angle sufficient to cause rapid and enhanced knockdown (KD) of the arthropod. The contact angle comprises an angle formed between a resting drop of the liquid formulation and the solid surface on which the drop rests measured, after a period of about 80 milliseconds (ms) or more from the time that a drop of the liquid formulation is deposited on the solid surface, at a contact point between a tangent line drawn on a liquid/vapor interface surface of the resting drop in contact with the solid surface and a tangent to the solid surface on which the drop rests.
US10299480B2 Antiviral agent
The invention relates to antiviral agents and specifically to synthetic biologically-active derivatives, and can be used in the pharmaceutical industry, in medicine, in plant husbandry and in biotechnology. The antiviral agent is based on poly-N1-hydrazino(imino)methyl-1,6-hexanediamine-poly-N1-amino(imino)methyl-1,6-hexane diamine of general formula (1), where: HX is an acid, n=3-20, and m=4-20, and which is active against viruses of humans, animals, plants, bacteria and fungi, said viruses being non-enveloped and enveloped and containing RNA or DNA. The antiviral agent exhibits a broad range of effectiveness, and is active against viruses both in intracellular and extracellular locations.
US10299478B2 Pyrazolyltriazolylpyridines as pesticides
The invention encompasses novel pyrazolyltriazolylpyridines of the general formula (I) in which the radicals A1-A4, W, Q, R1, R5 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (I). The compounds according to the invention are especially suitable for controlling insects and arachnids in agriculture, and ectoparasites in veterinary medicine.
US10299473B2 Low pH phenolic disinfectant without para tertiary amylphenol
The present invention relates to phenol containing disinfectants that have superior broad-spectrum antimicrobial efficacy versus traditional chemistry such as quaternary ammonium-containing disinfectants or aliphatic alcohols. Hydrotropic surfactants are utilized in combination with generally environmentally friendly phenol containing compounds such as ortho-benzyl parachlorophenol (OBPCP), ortho phenylphenol (OPP), or parachloro-meta-cresol (PCMC) in the presence of suitable solvents such as an aliphatic alcohol and also in the presence of an inorganic acid, such as phosphoric acid. The solutions are free of para tertiary amylphenol (PTAP), have a low pH and are very stable with respect to gamma irradiation. They can be used with respect to hard surface disinfection, and also as a tuberculocide, a fungicide, a bactericide, and a virucide.
US10299472B2 Coating material
The invention relates to an antimicrobial and preferably non-cytotoxic coating material and to use of said coating material.
US10299467B2 Animal model for type 2 diabetes and obesity
The present invention relates to the use of a genetically modified non-human animal as an animal model for obesity or obesity-related disorders, wherein the amount of Lysine-specific Demethylase 1 (LSD1) in at least one tissue or at least one cell type of said animal is reduced.
US10299464B2 Therapeutic toy device for an animal
A therapeutic toy device for an animal user. The device comprises an internal spine simulator comprising a plurality of weighted vertebra simulators, all coupled together in a manner intended to somewhat resemble the spine of a prey animal. The toy device is configured so that when the animal user plays with the toy, the act mimics the sensation of tackling an actual prey animal. This satisfies the animal's predator instincts, and thus gives the animal a more meaningful and satisfying sensory motor experience, thus improving well-being. The device, preferably produced from synthetic materials, will be surrounded by a synthetic covering, and optionally configured with other elements such as limb simulators, internal stuffing, and other features. The toy device will be offered in varying weights and configurations based on the size, weight and play-drive of an animal user.
US10299463B2 Grooming tool and methods
A grooming tool includes a handle and a head attached to the handle. The head has curved blades adjustable in at least an extended position and a non-extended position. Methods of grooming an animal can include selecting the length of the curved blades by adjusting the blades in at least an extended position or non-extended position.
US10299460B1 Alfalfa variety 68M802
The invention relates to the alfalfa variety designated 68M802. Provided by the invention are the seeds, plants and derivatives of the alfalfa variety 68M802. Also provided by the invention are tissue cultures of the alfalfa variety 68M802 and the plants regenerated therefrom. Still further provided by the invention are methods for producing alfalfa plants by crossing the alfalfa variety 68M802 with itself or another alfalfa variety and plants produced by such methods.
US10299453B2 Tomato line FIRXM12-4131
The invention provides seed and plants of tomato line FIRXM12-4131. The invention thus relates to the plants, seeds and tissue cultures of line FIRXM12-4131, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US10299452B2 Tomato hybrid SV8516TM and parents thereof
The invention provides seed and plants of tomato hybrid SV8516TM and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid SV8516TM and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US10299451B2 Tomato hybrid SV4483TD and parents thereof
The invention provides seed and plants of tomato hybrid SV4483TD and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid SV4483TD and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US10299450B2 Tomato hybrid SV6100TD and parents thereof
The invention provides seed and plants of tomato hybrid SV6100TD and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid SV6100TD and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US10299449B2 Vegetable carrying box
A vegetable carrying box includes a solution carrying box provided with a high-level liquid inlet and a low-level liquid outlet that are opposite to each other, where an area between the liquid inlet and the liquid outlet in the solution carrying box is provided with protruding diversion partitions to form a zigzag flow passage, and an atomizer is disposed in the flow passage.
US10299447B2 Targeted irrigation using a central pivot irrigation system with a sensor network
A system includes a plurality of optical sensors located along at least one pipe segment of a rotating arm that pivots around an irrigation area of a field, the plurality of optical sensors continuously monitors soil and vegetation conditions and transmits sensed data to a central computer, and a plurality of in-ground sensors scattered in the irrigation area of the field, the plurality of in-ground sensors continuously monitors soil conditions and transmits sensed data to a plurality of gateway devices located in the rotating arm, the plurality of gateway devices transmits data from the plurality of in-ground sensors to the central computer where data from the plurality of optical sensors and the plurality of in-ground sensors is integrated with external data to determine water and fertilizer needs based on which an irrigation schedule is created.
US10299446B2 Sealed connection for fluid conduit parts
An assembly of fluid conduit parts is disclosed along with a method of assembling, a method of manufacturing and an apparatus for manufacturing the one of the fluid conduit parts. The assembly includes a blow molded part having a first portion. A second part includes a tapered section and a sealing flange extends from the first portion towards a central axis of the first portion at a distance, an end of the sealing flange defines an opening. The second part inserts into the opening and at least part of the tapered section is of a size larger than the opening. The sealing flange flexes upon insertion of the second part into the opening to define a contact surface between the tapered section and the sealing flange that extends around a perimeter of the tapered section where the sealing flange contacts the tapered section.
US10299445B2 Center pivot irrigation system with uniformity of application of water under the corner arm
A center pivot irrigation system adapted for more uniform application of water. The system includes a pivot sprinkler arm with a first set of spaced apart nozzles. The system includes a first set of control valves each provided on the pivot sprinkler arm upstream of a nozzle. The irrigation system includes a corner sprinkler arm pivotally coupled to an end of the pivot sprinkler arm. The corner sprinkler arm includes a second set of spaced apart nozzles and a second set of control valves each provided upstream of a nozzle. The irrigation system includes a controller transmitting control signals to the first and second sets of control valves to open and close in a pattern defined by a valve pulsing pattern for the pivot sprinkler arm and a valve pulsing pattern for the corner sprinkler arm, whereby input water is applied in a uniform manner under the corner sprinkler arm.
US10299442B2 Rotary plant growing apparatus
A rotary plant growing apparatus is disclosed having a light emitting source operable to emit light. The apparatus also has at least one retaining component and a support operable to support the at least one retaining component in spaced relation to the light emitting source. A rotation mechanism is operable to rotate the at least one retaining component in a path around the light emitting source. A position adjustment mechanism is operable to move the at least one retaining component along a path extending between the at least one retaining component and the light emitting source so to adjust the distance between the at least one retaining component and the light emitting source.
US10299441B2 Horticulture lighting device and a method to stimulate plant growth and bio-rhythm of a plant
The present invention relates to a lighting device (100) to stimulate plant growth and bio-rhythm of a plant. The lighting device (100) comprising a solid state light source (102) arranged to emit direct red light having a wavelength of 600 to 680 nm, preferably 640 to 680 nm, and a wavelength converting member (106) arranged to receive at least part of said direct red light emitted from said solid state light source (102) and to convert said received direct red light to far-red light having a maximum emission wavelength of 700 to 760 nm, preferably 720 to 760 nm.
US10299436B2 Integrated reversing system with belt engagement
An agricultural harvester has a header and feeder drive system including a forward belt drive arrangement and a reverse belt drive arrangement. The forward belt drive arrangement includes a forward drive belt and a forward belt drive tensioner operated by an actuator. The reverse belt drive arrangement includes a reversing motor and a reverse drive belt selectively engaged with the feeder drive system by operation of the same actuator.
US10299435B2 Self-storing header auger
An agricultural vehicle including a chassis, a feeder housing supported by the chassis, and an attachment. The attachment includes a header coupled to the feeder housing. The header has a top support beam and a pair of lateral ends. The attachment also includes an auger that has an axis of rotation and is configured to rotate about the axis of rotation. The auger is pivotally connected to the header and is pivotable about a pivot axis. The auger is selectively pivotable between a stored position and an operating position such that in the stored position the auger does not obstruct a line of sight of an operator.
US10299425B2 Seed meter
A seed meter for an agricultural planter in which the seed disc is rotatably mounted within a seed meter housing. As the seed disc rotates, the apertures in the disc rotate along a seed aperture path through a horizontally adjacent seed pool area. The seed disc includes cavities disposed along the seed aperture path to agitate the seeds in the seed pool area. A singulator having multiple co-planar singulator surfaces is biased against the seed side surface of the seed disc.
US10299423B2 Computer controlled hydraulic bleed sequence
An agricultural machine or implement has a main frame section and at least one wing section, each having lift cylinders. A main shank frame may be pivotally attached to the main frame section and may have hydraulically adjustable gauge wheels. Wing shank frames may be pivotally attached to the wing sections and may also have hydraulically adjustable gauge wheels. Bypass circuits may be used to individually adjust the lift cylinders and gauge wheel cylinders. A controller or controllers is used to purge air from the lift cylinders, gauge wheel cylinders, cylinders used to raise the shank frames for transport, and from the bypass circuits. The purge routine may be selectable as individual steps, hydraulic subsystem purges, or as one automatic purge routine.
US10299421B2 Biasing system for harrows
A harrow implement comprises a tool bar and harrow sections extending rearward therefrom. Each of a plurality of hydraulic cylinders is connected between the tool bar and a corresponding harrow section. A hydraulic control is operative to supply pressurized hydraulic fluid such that the hydraulic cylinders exert a substantially constant selected bias force on the harrow sections. The hydraulic control is operative to direct pressurized hydraulic fluid into a first port on each hydraulic cylinder to exert a downward bias force on the plurality of harrow sections, and operative to direct pressurized hydraulic fluid into a second port on each hydraulic cylinder to exert an upward bias force on the plurality of harrow sections. The hydraulic cylinder can be configured to raise the harrow sections to an idle position above the ground, and to a transport position extending up from the tool bar.
US10306820B2 Systems for packaging electronic devices
A packaging system of an electronic device, in which the electronic device is mounted on a circuit board, may comprise: a first jig having a groove configured to contain the electronic device, the first jig having a surface on which a plurality of aligning posts are prepared to protrude; a circuit board supporting member connected to the circuit board to support the circuit board, the circuit board supporting member including a plurality of first guide holes into which the aligning posts are inserted; and/or a second jig configured to apply pressure to the circuit board and including a plurality of second guide holes into which the aligning posts are inserted.
US10306813B2 Apparatus with motor drive device, to which motor drive device can be easily attached
An apparatus with a motor drive device is provided with a support plate including an opening part for supporting the motor drive device. The support plate includes a first edge part around the opening part and a second edge part on the opposite side of the first edge part. The motor drive device includes a first recessed part formed on one end part in a predetermined direction, and a second recessed part formed on the other end part on the opposite side of the one end part. The first edge part is inserted into the first recessed part, and the second edge part is inserted to the second recessed part.
US10306807B2 Enhanced cooling design for computing device
Enhanced cooling for electronic components within a computing device is provided. Blowers are preferably leveraged as air movers, and an airflow deflection surface (preferably configured as a ramp) is disposed within a plenum to guide airflow under an electronic component (such as a hard disk drive or solid state drive), the electronic component being placed in an inverted alignment whereby a surface having a higher heat transfer rate is facing down (toward the blower), and then into an intake of the blower. Air output from the blower may then pass into a downstream plenum formed at least in part by the blower, an inverted downstream electronic component, and a support member thereof, thus providing serial cooling of the downstream component. Anti-recirculation flaps are preferably disposed at the air output of the blower.
US10306800B2 Cooling trough, cooler and power module assembly
The present invention discloses a cooling trough comprising an unflat surface, surrounding an opening of the cooling trough, configured with a height essentially decreasing inwardly. At least one supporting line, running around the opening of the cooling trough, is formed on the unflat surface. The at least one supporting line contacts a baseplate of a power module after the baseplate is attached to the unflat surface of the cooling trough. In addition, the present invention also discloses a cooler comprising the cooling trough and a power module assembly comprising the cooler.
US10306793B2 Longitudinal radial seal
Aspects and techniques of the present disclosure relate to an enclosure (20) that can include first and second housing pieces (22, 24) that cooperate to define an enclosed interior (26) of the enclosure (20). The first and second housing pieces (22, 24) mate at an interface (28) that extends about a continuous sealing loop (30). The enclosure (20) may include a seal (44) that extends about the continuous sealing loop (30) of the enclosure (20) at the interface (28) between the first and second housing pieces (22, 24). The seal (44) can include a retention portion (46) positioned within a channel (36) of the first housing piece (22) and a sealing flap (48) connected to the retention portion (46). The second housing piece (24) may include an outer flange (50) that extends about the continuous sealing loop (30) of the enclosure (20). The sealing flap (48) of the seal (44) can be compressed between the outer flange (50) and a rim element (32) of the enclosure (20).
US10306791B2 Flash drive packages and devices
A device configured to be coupled to a flash drive is described. The flash drive has a first attachment element coupled to the flash drive. The device comprises a housing having a recess configured to receive the flash drive. The recess has a plurality of contacts configured to interface with a plurality of standard contacts of the flash drive. The device also comprises a second attachment element configured to be magnetically attracted to the first attachment element of the flash drive. The first attachment element and the second attachment element have magnetic properties. The first attachment element and the second attachment element are capable of seating the flash drive in the recess.
US10306788B2 Flexible bottom shell and flexible display device
The present disclosure provides a flexible bottom shell, where the flexible bottom shell includes a first half shell, a second half shell, and a bendable part connected the first half shell and the second half shell, where the bendable part includes a plurality of connection plates, the plurality of the connection plates are successively bonded and are successively hinged together. Hinge pieces include a fixed plate, a fixed axle, and a pin axle. The fixed axle and the pin axle are perpendicular to a surface of the fixed plate. The fixed axle is connected to the fixed plate, and the pin axle is connected to the adjacent connection plates.
US10306787B2 Display device
A display device including a first supporter; a second supporter located opposite the first supporter; a display panel extending between the first supporter and the second supporter and extending to side parts of the first supporter and the second supporter; a third supporter; a fourth supporter located opposite to the third supporter; and a first pivotable strut bar pivotally connected to the first supporter and the second supporter.
US10306786B2 Mobile terminal comprising lid unit with key device
The invention relates to a mobile terminal comprising a lid unit arranged to substantially block an opening in a mobile terminal housing in an assembled state of the mobile terminal and arranged to allow access through the opening into the interior of the mobile terminal when removed from the opening, wherein the mobile terminal lid unit comprises at least one key device for controlling at least one function on the mobile terminal.
US10306779B2 Semiconductor support frame and storage device having the same
A substrate support frame includes a body having an upper surface for supporting a first module substrate and a lower surface for supporting a second module substrate, and including a plurality of extending portions that define a cavity for receiving semiconductor devices mounted on first and second module substrates, a curved portion protruding outwardly from a first one of the extending portions of the body corresponding to a position of a flexible substrate that electrically connects the first and second module substrates to each other, the curved portion having a curved sectional shape protruding toward the flexible substrate, and a fastening hole penetrating through the first one of the extending portions of the body and configured to receive a screw to couple the body to at least one of the first and second module substrates.
US10306777B2 Wiring board with dual stiffeners and dual routing circuitries integrated together and method of making the same
A wiring board with dual stiffeners and integrated dual routing circuitries is characterized in that first and second routing circuitries are positioned within and beyond a through opening of a first stiffener, respectively, and an array of vertical connecting channels are disposed on the second routing circuitry and laterally surrounded by a second stiffener. The mechanical robustness of the first and second stiffeners can prevent the wiring board from warping. The vertical connecting channels can offer electrical contacts for next-level connection. The first routing circuitry, positioned within the through opening of the first stiffener, can provide primary fan-out routing, whereas the second routing circuitry not only provides further fan-out wiring structure for the first routing circuitry, but also mechanically binds the first routing circuitry with the first stiffener.
US10306776B1 Substrate processing system printed-circuit control board assembly with one or more heater layers
A substrate processing system includes a processing chamber, a pedestal arranged in the processing chamber, and an electrostatic chuck (ESC) arranged on the pedestal. The ESC contains a printed circuit board assembly (PCBA) made up of a plurality of printed circuit board layers to mount circuitry that controls operation of the ESC. One or more of the printed circuit board layers includes a heater layer having one or more metal traces, which may be copper, to cover some or all of a surface of the heater layer sufficiently to provide heat to one or more of the remaining printed circuit board layers, to maintain the circuitry within a predetermined temperature range. The heat may be conducted directly among the various other printed circuit board layers, or may be conducted through vias in various ones of the printed circuit board layers.
US10306770B2 Thin-film capacitor manufacturing method, integrated circuit mounting substrate, and semiconductor device equipped with the substrate
A method for manufacturing a thin-film capacitor in a circuit substrate includes: forming, on a dielectric film formed on a surface of a support member, a first electrode layer of the thin-film capacitor; forming, on the dielectric film and the first electrode layer, an insulating base material of the circuit substrate so as to bury the first electrode layer; removing the support member and exposing a surface of the dielectric film on a side opposite to the first electrode layer; patterning the dielectric film so as to leave a dielectric layer overlapping the first electrode layer; forming a first through hole in the dielectric layer so as to expose a part of a surface, on a dielectric layer side, of the first electrode layer; and forming a second electrode layer of the capacitor so as to overlap the dielectric layer including the inside of the first through hole.
US10306764B2 Variable sensor interface for a control unit
The invention relates to a variable sensor interface for a control unit, this variable sensor interface including a circuit board which is provided with components. In a sensor interface which can easily be used for the use of different sensor types, the circuit board has a predefined conductive track layout having a plurality of predefined mounting locations, the mounting locations being provided with components in a sensor-specific manner.
US10306763B2 Electronic component, electric device including the same, and bonding method thereof
Provided is an electronic component including a pad region including a plurality of pads extending along corresponding extension lines and arranged in a first direction, and a signal wire configured to receive a driving signal from the pad region, wherein the plurality of pads include a plurality of first pads arranged continuously and a plurality of second pads arranged continuously, and extension lines of the plurality of first pads substantially converge into a first point and extension lines of the plurality of second pads substantially converge into a second point different from the first point.
US10306757B2 Circuit board and electronic device
A circuit board includes an insulation layer, a signal line formed over the insulation layer and extending in a direction X, and a conductor layer formed under the insulation layer. The insulation layer has periodic dielectric-constant distribution in a direction Y orthogonal to the direction X. The conductor layer includes a slit at a position corresponding to the signal line. The slit expands an electric field produced between the signal line and the conductor layer; causes less difference in dielectric constants of the insulation layer in the vicinity of the signal line (the difference is caused by the positional relationship between the signal line and the dielectric-constant distribution of the insulation layer); and reduces difference in signal transmission speeds caused by the positional relationship.
US10306755B2 Stretchable board
A stretchable board includes: a base material having stretchability; first and second electronic components mounted on the base material; a wire arranged on the base material; and first and second connectors for connecting the first and second electronic components and the wire to each other. At least a portion of the first electronic component and at least a portion of the second electronic component face each other in a planned stretching direction in which the base material includes: a facing zone interposed between the first and second electronic components in a planned stretching direction and a non-facing zone other than the facing zone on the base material, in which at least a portion of the first connector or at least a portion of the second connector are arranged in the non-facing zone, and in which at least one of the wires is arranged in the non-facing zone.
US10306752B2 Transparent conductor and device
According to one embodiment, a transparent conductor includes a transparent substrate; a metal nanowire layer disposed on the transparent substrate and including a plurality of metal nanowires; a graphene oxide layer covering the metal nanowire layer; and an electrical insulating resin layer disposed in contact with the graphene oxide layer.
US10306745B2 Accelerator and particle beam irradiation system
An accelerator 4 includes a circular vacuum container including circular return yokes 5A, 5B. An injection electrode 18 is disposed closer to an inlet of a beam extraction path 20 in the return yoke 5B than a central axis C of the vacuum container. Magnetic poles 7A to 7F are radially disposed from the injection electrode 18 at the periphery of the injection electrode 18 in the return yoke 5B. Recessions 29A to 29F are disposed alternately with the magnetic poles 7A to 7F in the circumferential direction of the return yoke 5B. In the vacuum container, a concentric trajectory region, in which multiple beam turning trajectories centered around the injection electrode 18 are present, is formed, and an eccentric trajectory region, in which multiple beam turning trajectories eccentric from the injection electrode 18 are present, is formed around the region.
US10306742B2 Droplet dispensing device, method for providing droplets, and light source for providing UV or X-ray light
The invention relates to a droplet dispensing device (4) comprising a reservoir (9) for containing a liquid medium (10), an outlet (11) for dispensing droplets of said liquid medium (10) from said reservoir (9), an actuation means (12) for generating and transmitting a mechanical oscillation at an excitation frequency, and a resonant structure comprising a piston (15) coupled to said actuation means (12) for transmitting said mechanical oscillation to the liquid medium (10) contained in said reservoir (9) such that droplets are formed from said liquid medium (10), wherein a resonance frequency of said resonant structure is sufficiently close to said excitation frequency, such that resonance occurs.The invention further relates to a UV or X-ray light source, comprising a droplet dispensing device (4) according to the invention, and a method for providing a stream, in particular a monodisperse stream, of droplets by means of the droplet dispensing device (4).
US10306741B2 Illumination system and mobile body
An illumination system includes: an illumination device; a time setter that sets a target time; and a controller that controls a color temperature of light emitted by the illumination device. The controller determines a target color temperature according to the target time, and causes the color temperature of the light emitted by the illumination device to be the target color temperature at the target time.
US10306733B2 Methods, systems, and apparatus for intelligent lighting
An ambient light sensor measures an ambient light level at one point in an illuminated environment, such as a warehouse, office, shop, cold-storage facility, or industrial facility, and provides an indication of the measured ambient light level to a processor. The processor maps the measured ambient light level to an estimated ambient light level at a different point in the illuminated environment from the measured ambient light level (e.g., a “task height” about three feet from a warehouse floor). The processor may determine the difference between the estimated ambient light level and a desired light level at the task height, and may change the artificial illumination provided by a light fixture to make the actual ambient light level at task height match the desired light level at the task height.
US10306729B2 Display with ambient-adaptive backlight color
An electronic device may be provided with a display having a backlight with light sources of different colors. The electronic device may include a color ambient light sensor that measures the color of ambient light and control circuitry that adjusts the color of light emitted from the backlight based on the color of ambient light. The light sources may include at least first and second light-emitting diodes that emit light having different color temperatures. The control circuitry may adjust the intensity of light emitted from the first light-emitting diode relative to the intensity of light emitted from the second light-emitting diode to produce a backlight color that more closely matches the color of ambient light. The first and second light-emitting diodes may include an ultraviolet light-emitting diode die and a blue light-emitting diode die that are mounted in a common semiconductor package.
US10306728B2 Color tunable light with zone control
A lighting system and method features full gamut color and white color correlated temperature (CCT) control of independently controlled zones. Each zone may be tuned to any color and/or white CCT. The result is a lighting system and method with a light-emitting face having zones of different colors and intensities that may be independently controlled in real time. The lighting system and method enables improved lighting effects for film, television, and still photography as compared to traditional panel lights that are uniform in color over the entire emission surface.
US10306727B2 Lighting apparatus and mobile terminal for controlling the same
A lighting apparatus and a mobile terminal controlling the same are disclosed. The lighting apparatus comprises a light source module generating light; and an electrochromic module varying a wavelength of light incident from the light source module, wherein the electrochromic module absorbs light of a specific one among wavelength ranges of the light incident from the light source module, in accordance with a lighting mode which is input. The mobile terminal controlling a lighting apparatus, which includes a light source module and an electrochromic module, comprises an input module receiving a user input; a communication module transmitting a lighting control signal to the lighting apparatus; a display module displaying a setup window for setting a lighting mode of the lighting apparatus; and a controller controlling the input module, the communication module and the display module.
US10306725B2 Light source drive device and vehicle lamp
Provided is a light source drive device including: a current supply device; and a light source device including a light emitting element that emits light by receiving drive current supplied from the current supply device, a temperature sensor that performs temperature detection at a position closer to the light emitting element than the current supply device, and a signal generation unit that outputs a control signal for controlling the drive current depending on a detected value of the temperature sensor to the current supply device. The signal generation unit generates a control signal for reducing the drive current depending on a temperature when the temperature detected by the temperature sensor is equal to or higher than a predetermined temperature.
US10306723B2 Load control device for a light-emitting diode light source having different operating modes
A load control device for regulating an average magnitude of a load current conducted through an electrical load may operate in different modes. The load control device may comprise a control circuit configured to activate an inverter circuit during an active state period and deactivate the inverter circuit during an inactive state period. In one mode, the control circuit may adjust the average magnitude of the load current by adjusting the inactive state period while keeping the active state period constant. In another mode, the control circuit may adjust the average magnitude of the load current by adjusting the active state period while keeping the inactive state period constant. In yet another mode, the control circuit may keep a duty cycle of the inverter circuit constant and regulate the average magnitude of the load current by adjusting a target load current conducted through the electrical load.
US10306716B1 Control signal switching system
A control signal switching system generates a light emitting module control signal for controlling a light emitting module, and the control signal switching system has a switching module and a transmission module. The switching module receives a switching control signal, a first control signal and a second control signal and output one control signal selected from the first control signal and the second control signal according to the switching control signal. The transmission module is connected to the switching module for receiving the one control signal selected from the first control signal and the second control signal and generates the light emitting module control signal for transmitting to the light emitting module. Therefore, the light emitting module is in operation according to the light emitting module control signal.
US10306715B2 Assembly with control gear for lamps
The invention relates to an assembly which consists of control gear for lamps and an electric circuit, said control gear comprising at least one energy transmission element, for example a transformer. The electric circuit has an inductive coupling element arranged in a stray magnetic field of the energy transmission element. The electric circuit comprises a voltage supply unit designed to produce a supply voltage for the electric circuit from energy absorbed from the stray magnetic or electromagnetic field of the energy transmission element.
US10306711B2 Microwave oven with dual doors
Novel microwave ovens and methods of using and manufacturing the same. Some microwave ovens include multiple doors and/or control keypads.
US10306707B2 Shaped heater for an aerosol generating system
A heater for heating an aerosol-forming substrate includes a plurality of elongate heating elements arranged in an elongate array. The elongate array has a support end with a first dimension, a heating end with a second dimension and a middle portion with a third dimension. The array is arranged to heat the substrate to form an aerosol. The third dimension is greater than the first dimension and greater than the second dimension. An electrically heated aerosol generating system can include the heater.
US10306704B1 Method and apparatus for retransmission
Aspects of the disclosure provide an apparatus for wireless communication. The apparatus includes a transceiver and a processing circuit. The transceiver is configured to transmit and receive wireless signals. The processing circuit is configured to detect an error of a previous scheduled transmission of data units from the apparatus to another apparatus. The other apparatus provides scheduled resources for transmission between the two apparatuses. Further, the processing circuit is configured to determine resources that are scheduled by the other apparatus for the apparatus to perform retransmission, and provide one or more of the data units in the previous scheduled transmission to the transceiver for retransmission using the scheduled resources.
US10306698B2 Method for setting up and operating a wireless network
A method is disclosed for establishing and operating a wireless network with a first communication unit, a second communication unit and a mobile communication unit. The first and second communication units are configured in each case as a server and the mobile communication unit is configured as a client. The mobile communication unit acquires connection set-up data of the first and second communication units. A wireless connection is established from the mobile communication unit to the first communication unit. The latter receives an instruction from the mobile communication unit via the wireless connection for configuration as a client of the second communication unit and the mobile communication unit transfers the connection set-up data of the second communication unit to the first communication unit. A wireless connection is then established from the mobile communication unit to the second communication unit.
US10306697B2 Apparatus and method for utilizing a radio access technology to connect to a telecommunication network
An apparatus, computer program, and method are provided for utilizing a particular radio access technology to connect to a telecommunication network before an expiration of a timer. A wireless communication device is provided including at least one hardware processor configured for sending a first request from the wireless communication device for connecting to a telecommunication network via a first base station for a first area. Such first base station implements a first radio access technology that has a first priority and a first data rate. In response to detecting a failure of the first request, a second radio access technology is utilized to connect to the telecommunication network before an expiration of a timer. Such second radio access technology has a second priority that is lower than the first priority and a second data rate that is lower than the first data rate. Further, in response to detecting that the wireless communication device has moved to a second area associated with a second base station before the expiration of the timer, a second request is sent via the second base station that implements the first radio access technology for utilizing the first radio access technology to connect to the telecommunication network before the expiration of the timer.
US10306696B2 Method and apparatus for handling RAN assistance information for radio link failure in wireless communication system
A method and apparatus for handling radio access network (RAN) assistance information in a wireless communication system is provided. A user equipment (UE) discards first broadcast RAN assistance information when a radio link failure (RLF) occurs, and applies second broadcast RAN assistance information after a specific time. That is, upon RLF, until when received broadcast RAN assistance information is not applied is defined.
US10306695B2 Procedures for managing secondary eNB (SeNB) radio link failure (S-RLF) in dual connectivity scenarios
Certain aspects of the present disclosure provide procedures for managing secondary eNB (SeNB) radio link failure (S-RLF) in dual connectivity scenarios. A user equipment (UE) may establish communication with a Master Evolved Node B (MeNB) and a Secondary eNB (SeNB). The UE may detect a Radio Link Failure (RLF) of a connection with the SeNB and may transmit an indication of the RLF to the MeNB, in response to the detection. The MeNB may take at least one action to manage the RLF, in response to receiving the indication of the RLF, for example, including transmitting a reconfiguration command to the UE. The SeNB may also detect the RLF and transmit an indication of the RLF to the MeNB over a backhaul connection, in response to the detection.
US10306694B2 Method and arrangement for connection re-establishment in a telecommunication system
The invention relates to a method in a user equipment and a user equipment (700) for controlling connection re-establishment between said user equipment and a network. The method comprises the steps of—receiving (501) a configuration message from the network defining at least one condition;—upon detection of connectivity problems (503) towards the first cell, evaluating said at least one condition (504);—if said at least one condition is fulfilled for a neighboring cell (B), applying at least one special criterion for initiating connection re-establishment to said neighboring cell (505), said at least one special criterion being different from at least one criterion that is applied if said at least one condition is not fulfilled. The invention furthermore relates to a method and an arrangement in a network node (800) for controlling connection re-establishment between the network and a user equipment (700).
US10306693B2 Service communication method, terminal and network device
Embodiments provide a service communication method. The method uses multiple Radio Access Technologies (RATs), and includes that: a terminal receives network capabilities of the multiple RATs; the terminal selects at least two RATs for a service of the terminal from the multiple RATs according to the network capabilities; and the terminal performs communication of the service by using the at least two RATs. In the embodiments, the terminal selects the at least two RATs for the service, so that manual setting of a user can be avoided, and thereby performance and convenience of the multiple RATs can be improved.
US10306692B2 Multi-path transmission control protocol
It is disclosed a MPTCP capable system for reducing disconnection time for a MPTCP capable UE (702), when it is leaving a coverage area of a second radio access type, when the second RAT typically has priority over the first RAT. This disclosure further comprises a controller of the second RAT (706), a MPTCP capable network proxy node(708), as well as a MPTCP network system therefore. In addition, methods and computer program in the respective arrangement are also presented.
US10306691B2 Method of providing services to user equipment having multiple antenna units
The present document is for a wireless communication using multiple antenna units based on new virtual user equipment (virtual UE) concept. A user equipment (UE), according to the present invention, receives service from a network in a wireless communication system by registering multiple antenna units of the UE as two or more virtual UEs with a first network entity of the network, wherein the first network entity is a network node for physical radio link control; and receiving the service from the network by the two or more virtual UEs. The two or more virtual UEs of the UE are recognized as one UE by network entities of the network other than the first network entity.
US10306687B2 Transmitting athletic data using non-connected state of discovery signal
Systems and methods for locating a wireless device in a “noisy environment” is provided. Embodiments relate to locating and wirelessly transmitting signals to a fitness device located proximate to other electronic devices is disclosed. In one embodiment, advertisement tokens and RSSI can be used for signal strength indication and then transmit a specific signal to the device. Examples include imprinting the fitness device to have a unique wireless identifier.
US10306683B2 Transmission opportunity scheduling
Scheduling of transmission opportunities to prevent collisions is contemplated. The transmission opportunities may be scheduled for terminal units where transmissions of one terminal unit may collide or otherwise interfere with transmissions of another terminal unit. The transmission opportunities may be scheduled according to a time-frequency grid to prevent collisions in a time domain and/or a frequency domain.
US10306681B2 Method and apparatus for signaling usable downlink subframes for low cost user equipment in wireless communication system
A method and apparatus for signaling usable downlink (DL) subframes for a low cost user equipment (UE) in a wireless communication system is provided. The low cost UE receives information on usable DL subframes for the low cost UE from a network, and performs reception by using the usable DL subframe from the network.
US10306678B2 Wireless communication system and method of controlling a transmission power
A base station is provided which notifies a mobile station of transmission power information for an uplink RACH, the mobile station transmits transmission delay estimation information on the RACH to the base station over the RACH at a transmission power based on the transmission power information, and the base station changes the transmission power information according to the transmission delay estimation information and notifies the mobile station of the changed transmission power information. The mobile station retransmits data or a preamble if the mobile station does not receive a notification that the base station has received the data or the preamble correctly after a predetermined time. The base station transmits the transmission power information over a BCH and a CPICH transmitted to a plurality of mobile stations.
US10306670B2 Systems and methods for a smart gateway SDN-based backhaul architecture for small cells
A new access networking framework is provided for supporting small cell deployments based on the sharing of network resources. A smart gateway framework flexibly accommodates eNB connections and dynamically assigns uplink transmission resources to the eNBs. Novel techniques are also introduced for sharing the small cell infrastructures among multiple operators through virtualization and SDN based reconfiguration.
US10306669B2 Physical uplink control channel (PUCCH) resource allocation
Systems and methods for determining an uplink control channel resource to use for transmitting uplink control information to a network node are disclosed. In some embodiments, a method performed by a wireless device comprises receiving a first downlink control channel message that schedules a first downlink shared channel transmission, receiving a second downlink control channel message that schedules a second downlink shared channel transmission, and determining an uplink control channel resource to use for transmitting uplink control information to a network node. The uplink control information comprises Hybrid Automatic Repeat Request (HARQ) feedback for both the first downlink transmission and the second downlink transmission, and determining the uplink control channel resources for transmitting the uplink control information comprises determining the uplink control channel resources based on: (a) signaling received from the network node and (b) resource determination performed by the wireless device based on a latest received one of the first downlink control channel message and the second downlink control channel message. The method further comprises transmitting the uplink control information using the determined uplink control channel resource.
US10306665B2 Bundling data transfers and employing tail optimization protocol to manage cellular radio resource utilization
To facilitate increasing power and resource efficiency of a mobile device, in the mobile device, with regard to periodic or one-time data transfers, a communication management component can analyze information comprising data transfer parameter information, including jitter information, associated with each application of a subset of applications used by the device and can desirably schedule and/or bundle data transfers associated with the applications to reduce the number of separate data bursts to transfer that data to thereby reduce use of wireless resources and power consumption by the device. A push notification system can receive respective jitter information associated with each application from the mobile device, and the push notification system can desirably schedule and/or bundle push notifications to reduce the number of separate data bursts sent to the device to reduce use of wireless resources and power consumption by the device.
US10306662B2 Method for configuring and scheduling partial subframe in wireless access system supporting unlicensed band, and device for supporting same
The present invention relates to, in a wireless access system supporting an unlicensed band, methods for configuring and scheduling a partial subframe (pSF) and devices for supporting same. A method for receiving data through a cell (U cell) configured in an unlicensed band in a wireless access system for supporting an unlicensed band comprises the steps of: a terminal receiving control information from a base station through a primary cell (P cell) which is configured in a licensed band; and the terminal receiving, on the basis of the control information, downlink data from the base station through an unlicensed band cell (U cell) which is configured in an unlicensed band, wherein, if cross-carrier scheduling is configured in the terminal, the terminal not anticipating, as the subframe for receiving the downlink data, a partial subframe (pSF) which is transmitted in a state of having the first part of symbol emptied, wherein the pSF is configured to be smaller than one subframe.
US10306659B2 Data transmission method and device
The present invention relates to the communications field, and discloses a data transmission method and device, so as to resolve a problem of low efficiency and excessively much power consumption when user equipment performs blind detection on a scheduling control channel. A specific solution is: receiving, by a first device, scheduling control channel length information, performing, by the first device, blind detection in a preset search space according to the scheduling control channel length information, and after detecting a scheduling control channel corresponding to the scheduling control channel length information, obtaining, by the first device, resource allocation information carried on the scheduling control channel. The present invention is applied to data transmission.
US10306656B2 Resource management method and apparatus
The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). The base station determines a cell edge user, receives information of a cell edge user in an adjacent cell; according to the information of cell edge users in the cell and the adjacent cell, establishes a virtual cell including the cell edge users, transmits configuration information of the cell edge user in the cell and configuration information of the cell to base stations each of which a cell edge user in the virtual cell is located at, and receives configuration information of each cell edge user and configuration information of a cell where the each cell edge user is located from a base station where the each cell edge user is located, and configures uplink-downlink resources and a transmission mode for the virtual cell.
US10306651B2 Method and network node for scheduling
A method (20) of scheduling performed by a network node (3) is disclosed. The network node (3) comprises a distributed local oscillator architecture in which elements (181, . . . , 18i, . . . , 18N) of an antenna array (14) have at least partly uncorrelated local oscillator signals, and the network node (3) has wireless connectivity to at least two transmitter nodes (2a, 2b). The method (20) comprises calculating (21) a phase noise value between one or more layers received in each element (181, . . . , 18i, . . . , 18N) from a first transmitter node (2a) and one or more layers received in each element (181, . . . , 18i, . . . , 18N) from a second transmitter node (2b), and determining (22) a scheduling allocation for the at least two transmitter nodes (2a, 2b), taking the calculated phase noise value into account. A network node (3), computer program and computer program product are also provided.
US10306649B2 Methods for identifying mobile stations that are near neighbor cells
Uplink signals transmitted from each of a plurality of UE devices being served by a serving eNB are received at a neighbor cell eNB. Information regarding the uplink signals received by the neighbor cell eNB is then sent to the serving eNB. The UE devices are identified based on the information. An aggregate load level of the UE devices is determined based on resource load requirements of each UE device. In some instances, it is determined which of a plurality of deactivated neighbor cells should be activated based on load levels associated with one or more UE devices that are determined to be near each of the plurality of deactivated neighbor cells.
US10306648B2 Communications system, infrastructure equipment, communications devices and method
A method of transmitting/receiving data between a communications device and a mobile communications network including a wireless access interface providing communications resources within a system bandwidth and in time divided units allocated to communications devices of first and second types having different capabilities. The method generates, at the communications device, a random access message, by selecting a sequence from a predetermined set of sequences, which have been allocated to the communications devices of the second type and transmitting the random access message from the communications device to the wireless communications network, and in response to the random access message, receives a random access response at the communications device transmitted according to the capability of the communications device of second type, the random access message being recognized as from a communications device of second type from the selected one of the predetermined sequences allocated to the communications devices of second type.
US10306642B2 Telecommunications apparatus and methods
A wireless telecommunications system in which downlink communications are made using a radio interface that spans a system frequency bandwidth (host carrier) and supports at least some communications from a base station to least some terminal devices within a plurality of restricted frequency bands (virtual carriers) which are narrower than and within the system frequency bandwidth. A terminal device conveys an indication of its identity, e.g. an IMSI, to the base station during an initial connection procedure as the terminal device seeks to access the radio interface. The terminal device and the base station both determine a selected restricted frequency band from among the plurality of restricted frequency bands based on the identity of the terminal device in the same way. Thus the terminal device and the base station select the same restricted frequency band and can accordingly configure their respective transceivers to allow for downlink communications between them within the selected restricted frequency band.
US10306637B2 Radio base station and user terminal
A radio base station according to an embodiment is a radio base station configured to use a specific frequency band which includes a plurality of component carriers having a predetermined bandwidth and which is allowed to be utilized by a plurality of network operators or a plurality of communication systems. The radio base station comprises: a controller configured to select, from among the plurality of component carriers, a target component carrier in which a reference signal used in the specific frequency band should be transmitted; and a transmitter configured to use the target component carrier to transmit the reference signal. The controller selects, as the target component carrier, a first component carrier that satisfies a first condition. The first condition is that an interference power amount falls below a predetermined threshold value.
US10306636B2 Method and device for carrier aggregation configuration based on multi-band capability
A frequency band basis for access of user equipment (UE) to a serving cell is determined. Configuration information for an inter-frequency neighbor cell, at a preset physical frequency point, of the frequency band basis for the access of the UE to the serving cell, and one or more carrier aggregation combinations supported by the UE are acquired. A target frequency band of a secondary carrier required to be configured by the UE is determined according to the configuration information for the inter-frequency neighbor cell and the one or more carrier aggregation combinations supported by the UE. A corresponding reconfiguration message is sent to the UE and an inter-frequency neighbor cell, at the preset physical frequency point, of the target frequency band is used as a secondary serving cell according to a carrier aggregation capability of the UE in the target frequency band.
US10306634B2 Communication device and method for processing a signal
According to an example, a communication device is described comprising a receiver configured to receive a signal, a divider configured to divide the signal into signal components, an estimator configured to estimate, for each signal component, an expected processing error which is made when, instead of a first processing scheme, a second processing scheme is used to process the signal component, wherein the first has a higher processing effort than the second, a determiner configured to determine, for each signal component, whether to process the signal component by the first or by the second processing scheme based on the expected processing errors.
US10306633B2 Apparatus and method for operating resource in wireless communication system
A method for operating a resource in a base station (BS) in a wireless communication system supporting multi-carrier is disclosed. The method includes acquiring reference information related to at least one resource block (RB) to be allocated to a user equipment (UE), determining a RB type to be used in the at least one RB based on the reference information, and transmitting, to the UE, information related to the RB type to be used in the at least one RB. The present disclosure relates to a communication method and system for converging a 5th-generation (5G) communication system for supporting higher data rates beyond a 4th-generation (4G) system with a technology for internet of things (IoT), which may be applied to intelligent services based on the 5G communication technology and the IoT-related technology.
US10306632B2 Techniques for transmitting channel usage beacon signals over an unlicensed radio frequency spectrum band
Techniques are described for wireless communication. A first method includes winning a contention for access to an unlicensed radio frequency spectrum band, and transmitting at least a portion of a channel usage beacon signal (CUBS) over the unlicensed radio frequency spectrum band. The at least portion of the CUBS is transmitted in a number of frequency interlaces of the unlicensed radio frequency spectrum band. A second method includes winning a contention for access to an unlicensed radio frequency spectrum band; determining whether the contention is won within a threshold time before a next symbol period boundary; and transmitting at least a portion of a CUBS over the unlicensed radio frequency spectrum band. The at least portion of the CUBS is transmitted during a preamble including a fractional period of a first symbol period. The at least portion of the CUBS may be based at least in part on the determining.
US10306631B2 Communication apparatus, communication method and communication system
Communication operations are optimally conducted by applying space-division multiple access in which wireless resources on a spatial axis are shared among a plurality of users. By applying an RD protocol to a communication system that conducts space-division multiple access, spatially multiplexed frames in a TXOP are made more efficient. By specifying a frame length for reverse direction frames with reverse direction permission information and having respective transmitters of reverse direction frames make their frame lengths uniform while respecting the specification, AGC operation stabilizes. Also, a transmit start time for reverse direction frames can be specified by reverse direction permission information, and respective transmitters of reverse direction frames can transmit frames at the same time while respecting the specification.
US10306630B2 Systems and methods for determining frame structure and association timing
A user equipment (UE) is described. The UE includes a processor. The UE also includes memory in electronic communication with the processor. Instructions stored in the memory are executable to determine a radio frame structure based on a self-contained subframe pattern. The instructions are also executable to receive a downlink data assignment and decode downlink data. The instructions are further executable to determine a hybrid automatic repeat request acknowledgement/negative acknowledgement (HARQ-ACK) feedback timing of the downlink data. The instructions are additionally executable to transmit HARQ-ACK feedback of the downlink data based on the determined HARQ-ACK feedback timing. The instructions are also executable to receive uplink scheduling information. The instructions are further executable to determine an uplink scheduling timing for a scheduled uplink transmission. The instructions are additionally executable to transmit uplink data in a scheduled subframe.
US10306629B2 Wireless communication device, wireless communication system, and computer program product
According to an embodiment, a wireless communication device is one of a plurality of wireless communication devices constituting a wireless communication system. The device includes one or more processors configured to have a network topology construction mode and a time-division wireless communication mode. A first cycle as a communication cycle in the network topology construction mode is shorter than a second cycle as a communication cycle in the time-division wireless communication mode.
US10306628B2 Method and apparatus for determining control channel search space
Embodiments of the present disclosure provide a method for determining a control channel search space. The method includes: determining numbers of at least two physical resource sets; determining, according to the numbers, location offsets of search spaces corresponding to the at least two physical resource sets, wherein the determined location offsets of the search spaces comprises at least two different location offsets of the search spaces; and determining, according to the location offsets of the search spaces corresponding to the at least two physical sets, the search spaces corresponding to the at least two physical resource sets. By grouping and numbering resources, and determining different location offsets for different search spaces, a probability of control channel search space conflict can be reduced. Thereby, resources of control channels can be maximized in a case of multiple users, and communication efficiency can be improved.
US10306627B2 Techniques for allocating resources in low latency wireless communications
Various aspects described herein relate to receiving wireless communications from an access point, determining resources of the wireless communications associated with a search space for control information in the received wireless communications, and performing one or more of a set of blind decodes over the search space to decode at least low latency control information associated with a low latency communication technology, wherein the low latency communication technology utilizes a transmission time interval (TTI) having a duration that is less than a subframe of a legacy communication technology.
US10306626B2 Device
[Object] To enable a terminal device to more easily maintain synchronization for communication of a cellular system in a frequency band shared between the cellular system and a wireless LAN.[Solution] There is provided a device including: a communication processing unit configured to perform communication of a cellular system in a frequency band shared between the cellular system and a wireless LAN within a first period and stop the communication of the cellular system in the frequency band within a second period. The first period is one or more subframes including a subframe in which a synchronization signal of the cellular system is transmitted, and the second period is one or more other subframes not including the subframe in which the synchronization signal is transmitted.
US10306625B2 Methods and network nodes for use in a communication network
According to an aspect, there is provided a method of operating a network node in a communication network. The method comprises determining (121) a preferred configuration for one or more flexible subframes in a frame, the frame comprising one or more subframes allocated to uplink transmissions, one or more subframes allocated to downlink transmissions and one or more flexible subframes that can each be dynamically allocated to either uplink transmissions or downlink transmissions; and transmitting (125) a message to a neighbouring network node in the communication network through an inter node interface, the message indicating the preferred configuration for the one or more flexible subframes.
US10306621B2 Transmitting device, receiving device, transmitting method, and receiving method
In a transmitting device, each of the plurality of mapping candidates that make up the search space is configured from the same number of control channel elements as an aggregation level value, the control channel elements are obtained by dividing each physical resource block into a predetermined number, and the quantity of resource elements contained in each of the predetermined number of control channel elements in each physical resource block adopts at least two types of values. A search space setting unit sets a search space of which the aggregation level value is 2 or more so that, between a plurality of mapping candidates, variation in the total quantity of resource elements contained in the control channel elements that make up the mapping candidates is as small as possible.
US10306618B2 Method and wireless device for receiving downlink control channel
The disclosure of the present specification provides a method for receiving a downlink control channel, which is repeated on a plurality of downlink subframes, by a wireless device in a wireless communication system. The method may comprise the steps of: attempting, by the wireless device, blind decoding of the downlink control channel, using one or more of multiple scrambling codes; when the blind decoding is successful, determining, by the wireless device, a repetition level for the downlink control channel on the basis of a scrambling code by which the wireless device has been successful in the blind decoding; and determining, by the wireless device, the number of repetitions of the downlink control channel according to the repetition level.
US10306617B2 Terminal device, integrated circuit, and communication method
Provided is a terminal device communicating with an EUTRAN. The terminal device simultaneously receives, in the same subframe, a PBCH, a PDCCH, and a PDSCH in a downlink in a serving cell, a PBCH, a PDCCH, and a PDSCH in the downlink in a non-serving cell, and a physical channel in the non-serving cell in a sidelink, and monitors the PDCCH in a common search space in the downlink of the non-serving cell upon being configured to decode the physical channel in the sidelink in the non-serving cell.
US10306616B2 Control data transmission over a data channel by a controlling base station
A controlling base station sends, to a wireless communication device, control data related to communication between a communication base station and the wireless communication device. The control data is transmitted in accordance with a communication specification and is transmitted to allow reception by the wireless communication device of the control data within a data channel having a frequency and time allocated by the communication specification for the wireless communication device to receive data transmissions from the communication base station.
US10306610B2 Method for receiving control information in wireless communication system and apparatus therefor
The present invention relates to a method and an apparatus for a terminal for receiving control information in a wireless communication system. More specifically, the method comprises a step for monitoring an enhanced physical downlink control channel (EPDCCH) set comprised in an EPDCCH, wherein an aggregation level for monitoring the EPDCCH set is determined according to the configuration regarding the EPDCCH set.
US10306609B2 Method and apparatus for controlling uplink control information in wireless communication system
Provided is a method and an apparatus for transmitting uplink control information by a terminal in wireless communication system. When a PUCCH resource used for transmitting only periodic CSI from a subframe, the resource is a first resource, and a resource indicated by ARI is a second resource, when a setting allows transmitting together ACK/NACK and the periodic CSI through a PUCCH from the same subframe, the first resource and the second resource are mutually exclusive, and the second resource that is used for transmitting together the ACK/NACK and the periodic CSI uses the resource indicated by the ARI from resources determined by an RRC.
US10306604B2 Method for acquiring system frame number by terminal, terminal, and mobile communication system
A System Frame Number (SFN) acquisition method is provided. The System Frame Number (SFN) acquisition method of a terminal according to the present invention includes receiving a first message for adding a secondary cell of a secondary base station from a primary cell of a primary base station, receiving a Master Information Block (MIB) broadcast in the secondary cell, and acquiring a SFN information for the secondary cell from the MIB, and applying the SFN information to at least one cell of the secondary base station.
US10306602B2 Data transmission method and apparatus
Embodiments of the present invention provide a data transmission method and apparatus. The data transmission method includes: receiving, by a third site, a first transmit frame transmitted by a first site to a second site, and acquiring a transmission end moment of the first transmit frame; transmitting, by the third site, a second transmit frame to a fourth site, and instructing the fourth site to delay returning a response frame; and receiving, by the third site after at least one preset time length after transmission of the second transmit frame ends, the response frame transmitted by the fourth site; where a transmission end moment of the second transmit frame is not later than the transmission end moment of the first transmit frame. The embodiments of the present invention implement that the third site can also transmit data when the first site transmits data, which improves system transmission efficiency.
US10306601B2 Handling the ambiguity of the sending of HS-SCCH order in node B
A method in a network node is disclosed. The method comprises receiving, from a radio network controller (RNC), a request to send a high speed signaling control channel (HS-SCCH) order to a user equipment (UE) according to one of a first or second fast Transmission Time Interval (TTI) switching mode, the HS-SCCH order indicating that the UE should perform TTI switching. The method further comprises communicating, to the RNC in response to receiving the request to send the HS-SCCH order to the UE, feedback indicating a fast TTI switching mode supported by the network node.
US10306600B2 Method for limiting use of exceptional resource performed by user equipment in wireless communication system and user equipment using method
The present invention provides a method for the performance of a device-to-device (D2D) operation by a user equipment (UE) in a wireless communication system, the method comprising the steps of: starting to use an exceptional resource; determining whether a condition for suspending the use of the exceptional resource is satisfied; and when the condition for suspending the use of the exceptional resource is satisfied, suspending the use of the exceptional resource, wherein the condition for suspending the use of the exceptional resource is a suspension condition in an RRC idle state.
US10306599B2 Method and device for allocating resources in wireless communication system supporting D2D communication
A resource allocation method and device capable of preventing resource conflict in a wireless communication system supporting device-to-device (D2D) communication is provided. The resource allocation method includes transmitting to a base station, by a relay user equipment (UE) located within a coverage of the base station, a message comprising indication information related to the relay UE, and performing, by the relay UE, D2D communication with a remote UE located out of the coverage by using a first resource, the first resource being allocated by the base station based on the indication information.
US10306597B2 Method and apparatus for beam-level radio resource management and mobility in cellular network
Methods and apparatuses for beam-level radio resource management and mobility are provided. A user equipment (UE) includes a transceiver and at least one processor operably connected to the transceiver. The transceiver is configured to receive measurement resource configuration information that includes at least one measurement reference signal (RS) resource configuration, transmit a trigger request, and receive a measurement report trigger. The at least one processor is configured to calculate, in response to receipt of the measurement report trigger, a measurement report from a measurement RS. The transceiver is further configured to transmit the measurement report. The RS resource configuration is associated with a radio resource unit.
US10306596B2 Method and system for connectionless transmission during uplink and downlink of data packets
A method and system for uplink-downlink transmission of data packets in a wireless cellular network, during idle state of User Equipment (UE) using connectionless transmission is disclosed. The method establishes S1 common bearer between a Radio Access Network (RAN) node and Serving Gateway (SGW) and S5 common bearer between the SGW and Packet Data Network Gateway (PGW). The method defines a modified Uu interface between the UE and the RAN node. The method appends data packets with UE Identifier (ID) and routing information as packet header information to independently route data packets through wireless cellular network in a self-sustainable manner using the established common bearers and the modified Uu interface. The method secures data packets by providing integrity and ciphering protection. The method eliminates cost of dedicated bearer set up and reduces signaling overhead on the Uu interface thereby improving network efficiency and battery life of the UE.
US10306594B2 Uplink coverage enhancements
Aspects of the present disclosure provided techniques for enhancing uplink coverage. A method for wireless communications by a wireless device is provided. The method generally includes obtaining a payload of data to be transmitted to a base station, selecting at least one uplink control channel and a number of transmission time intervals (TTIs), and conveying the data in the at least one uplink control channel over the number of TTIs, wherein different portions of the data are conveyed in different TTIs.
US10306590B2 Paging for mmW shared radio frequency spectrum bands
Methods, systems, and devices for wireless communication are described. The described techniques provide for transmitting, at a base station, a contention exempt broadcast paging message that includes partial paging information for a user equipment (UE), receiving a random access request message transmitted by a UE in response to the broadcast paging message, and transmitting a unicast paging message which includes complete paging information. The described techniques further provide for determining, at a base station, a first paging opportunity window (POW) and a second POW for a UE, performing a LBT procedure during the first POW, transmitting a broadcast paging message including partial paging information for the UE during the first POW, performing a second LBT procedure during the second POW, transmitting a unicast paging message to the UE during the second POW, the unicast paging message including complete paging information for the UE.
US10306584B2 User equipment, computer readable medium, and method to determine the mobility of user equipment in a long-term evolution network
User Equipment (UE), computer readable medium, and method to determine a mobility of the UE are disclosed. The UE may include circuitry configured to determine a plurality of signals from a serving cell. The each signal of the plurality of signals may be one or more of: a reference signal receive power (RSRP), a reference signal receive quality (RSRQ), a received signal strength indicator (RSSI), a signal-to-noise ratio (SNR), a signal-to-interference-ratio (SIR), a signal-to-interference-plus-noise ratio (SINR), and a CQI. The circuitry may be configured to determine a measure for each of a window size of the plurality of signals. Each measure may be a variance of the plurality of signals, a standard deviation of the plurality of signals, a percent confidence interval (CI) of a mean of the measure, and a linear combination of measures. The circuitry may determine whether the UE is stationary based on one or more measures.
US10306583B2 Systems and methods to evaluate accuracy of locations of mobile devices
Systems and methods to identify a region in which a mobile device is located, by: applying device attributes of the mobile device and region attributes of coordinates of the mobile device to a predictive model to generate an accuracy indicator, identifying a plurality of locations from the coordinates of the mobile device that represent one point and the accuracy indicator, converting coordinates of the locations to cell identifiers of a grid reference system, determining region(s) containing the locations by finding matching cell identifiers that are pre-associated with the region(s), and determining a confidence level of a region that contains at least a portion of the locations based on the weights of locations in the portion. The region is identified in response to a determination that the confidence level is above a threshold.