Document Document Title
US10023985B2 Method of controlling a washing machine
Washing machine control method including an outer tub and an inner tub containing clothes rotatably disposed therein. The method includes detecting an amount of dry clothes, supplying water between the outer and inner tub such that the clothes are not wetted, discharging water from the outer tub to a circulation channel and introducing water into the inner tub through the circulation channel to wet the clothes, discharging unabsorbed water collected in the outer tub to the circulation channel such that a water level in the outer tub becomes zero while detecting a flow rate of water, and determining an amount of circulation water discharged to the circulation channel based on the flow rate detected until a water level in the outer tub becomes zero and determining properties of the clothes based on the amount of circulation water and a predetermined anticipated amount of circulation water corresponding to the amount of dry clothes detected.
US10023974B2 Substrates for semiconductor devices
A method of fabricating a composite semiconductor component comprising: (i) providing a bowed substrate comprising a wafer of synthetic diamond material having a thickness td, the bowed substrate being bowed by an amount B and comprising a convex face and a concave face; (ii) growing a layer of compound semiconductor material on the convex face of the bowed substrate via a chemical vapour deposition technique at a growth temperature T to form a bowed composite semiconductor component comprising the layer of compound semiconductor material of thickness tsc on the convex face of the bowed substrate, the compound semiconductor material having a higher average thermal expansion coefficient than the synthetic diamond material between the growth temperature T and room temperature providing a thermal expansion mismatch ΔTec; and (iii) cooling the bowed composite semiconductor component, wherein the layer of compound semiconductor material contracts more than the wafer of synthetic diamond material during cooling due to the thermal expansion mismatch ΔTec, wherein B, td, tsc, and ΔTec are selected such that the layer of compound semiconductor material contracts on cooling by an amount which off-sets bowing in the bowed substrate thus pulling the bowed composite semiconductor component into a flat configuration, the layer of compound semiconductor material having a tensile stress after cooling of less than 500 MPa.
US10023973B2 Dopant feeding device for dispensing dopant
A dopant feeding device for releasing dopant into a feeder system during doping of a crystal growing system includes a dopant container for holding the dopant, a lower valve, and an upper valve. The dopant container includes a wall defining a lower opening for releasing the dopant therethrough. The lower valve is positioned adjacent to the lower opening and is movable between a closed position that is in contact with the wall to prevent passage of dopant through the lower opening and an open position that is spaced from the lower opening to allow passage of dopant therethrough. The upper valve is positioned above and connected to the lower valve. The upper valve is disposed within the dopant container and is movable between a first position that is spaced from the dopant container and a second position that is in contact with the dopant container.
US10023970B2 Dynamic current distribution control apparatus and method for wafer electroplating
Methods, systems, and apparatus for plating a metal onto a work piece are described. In one aspect, an apparatus includes a plating chamber, a substrate holder, an anode chamber housing an anode, an ionically resistive ionically permeable element positioned between a substrate and the anode chamber during electroplating, an auxiliary cathode located between the anode and the ionically resistive ionically permeable element, and an insulating shield with an opening in its central region. The insulating shield may be movable with respect to the ionically resistive ionically permeable element to vary a distance between the shield and the ionically resistive ionically permeable element during electroplating.
US10023966B2 Electrolytic cell equipped with concentric electrode pairs
A bipolar electrolytic cell particularly useful for electrochemical processes carried out with periodic reversal of polarity is provided. The cell is equipped with a series of concentric electrode pairs, the innermost pair and the outermost pair being connected to the poles of a DC generator and the intermediate pairs acting as bipolar electrodes. The different pairs of electrodes are arranged and connected in such a way that, at each stage of the process, the overall cathodic area is equal to the anodic area.
US10023964B2 Break-resistant anode assemblies for cathodic protection systems and methods of installing the same
Various break-resistant anode assemblies and method of installing the same in the ground are disclosed. Each anode assembly (20) basically comprises an anode (22), at least one pulling cable (24), and a protective nose cone (26). The nose cone is a hollow member receiving the leading end (22A) of the anode and from which the anode's electrical conductor (28) extends. The nose cone includes a tapered leading surface (32) that facilitates and guides the anode assembly as it is pulled through the ground, while protecting the anode. A break-away mechanism (54) may also be provided to ensure that no more than a maximum pulling force is applied to the anode assembly during its installation to ensure that the anode is not damaged.
US10023963B2 Corrosion inhibiting additive
A corrosion resistant article including an aluminum substrate and a corrosion-inhibiting cerium based corrosion inhibitor corrosion inhibiting additive on the aluminum substrate, the corrosion inhibiting additive comprising an anodic corrosion inhibitor and a cathodic corrosion inhibitor, the anodic corrosion inhibitor greater than 25 wt % of the total inhibitor.
US10023961B2 Installation for depositing films onto a substrate
An installation, comprising a chamber comprising two ends, a transport unit and a support unit which introduce a two-sided substrate into the chamber, a stabilized high-voltage high-frequency power supply of at least 200 kW, comprising an HF transformer comprising a primary and a secondary circuit connected to terminals, at least two electrodes being connected to the terminals of the secondary circuit, said electrodes being placed on each side of the substrate, at least one dielectric barrier placed between the at least two electrodes; a power supply regulation/control unit placed upstream of the HF transformer that is capable of increasing an active power/reactive power ratio, an introducing unit for introducing at least one reactive substance into the chamber, and an extracting unit for extracting residual substances, wherein an adjustable inductor is placed in the secondary circuit of the transformer in parallel with a circuit comprising the at least two electrodes, and the adjustable inductor enables a phase shift between a voltage generated between the electrodes and a total current delivered by the high-voltage source to be modulated, and the power supply regulation/control unit, placed on the primary circuit of the transformer, and/or a unit for controlling the inductor being capable of generating harmonics extending a time during which a current flows between the electrodes, wherein the installation is suitable for depositing a film onto an inorganic substrate.
US10023960B2 Process gas management for an inductively-coupled plasma deposition reactor
Embodiments related to hardware and methods for processing a semiconductor substrate are disclosed. One example film deposition reactor includes a process gas distributor including a plasma gas-feed inlet located to supply plasma gas to a plasma generation region within the film deposition reactor and a precursor gas-feed inlet located to supply film precursor gas downstream of the plasma generation region; an insulating confinement vessel configured to maintain a plasma generation region at a reduced pressure within the film deposition reactor and an inductively-coupled plasma (ICP) coil arranged around a portion of a sidewall of the insulating confinement vessel and positioned so that the sidewall separates the plasma generation region from the ICP coil; and a susceptor configured to support the semiconductor substrate so that a film deposition surface of the semiconductor substrate is exposed to a reaction region formed downstream of the process gas distributor.
US10023959B2 Anti-transient showerhead
Showerheads for semiconductor processing equipment are disclosed that include various features designed to minimize or eliminate non-uniform gas delivery across the surface of a wafer due to gas flow transients within the showerhead.
US10023955B2 Seed layer laser-induced deposition
A method of creating a layer of a target deposit-material, in a first target pattern, on a substrate surface. The substrate surface is placed in a vacuum and exposed to a first chemical vapor, having precursor molecules for a seed deposit-material, thereby forming a first substrate surface area that has adsorbed the precursor molecules. Then, a charged particle beam is applied to the first substrate surface area in a second target pattern, largely identical to the first target pattern thereby forming a seed layer in a third target pattern. The seed layer is exposed to a second chemical vapor, having target deposit-material precursor molecules, which are adsorbed onto the seed layer. Finally, a laser beam is applied to the seed layer and neighboring area, thereby forming a target deposit-material layer over and about the seed layer, where exposed to the laser beam.
US10023953B2 High purity refractory metal powders and their use in sputtering targets which may have random texture
A method for making a sputtering target including steps of encapsulating and hot isostatically pressing at least one mass of metal powder (e.g., tantalum), having a particle size ranging from about 10 to about 1000 μm, with at least about 10 percent by weight of particles having a particle size greater than about 150 μm (for example, about 29 to about 56 percent (e.g., about 35 to about 47 percent) by weight of the particles in the at least one mass of metal powder having a particle size that is larger than 150 microns, but below about 250 μm), for defining at least a portion of a sputtering target body, having an essentially theoretical random and substantially uniform crystallographic texture.
US10023950B2 Vapor deposition mask and organic el display device
The purpose is providing a vapor deposition mask with high rigidity which can evaporate a uniform thickness film. A vapor deposition mask including a mask body having a main opening, a side surface of the main opening, an upper surface intersecting the side surface, and a lower surface opposing the upper surface, a first insulator contacting the lower surface, and a second insulator contacting the upper and side surfaces, wherein the first insulator includes a first region inside the main opening, and a first opening in the first region, the second insulator includes a second region inside the main opening, and a second opening in the second region, the mask body is sandwiched between the first and second insulators, and one of the first and second insulators includes a region located inside the main opening more centrally than the other and not overlapping with the other and the mask body.
US10023949B2 Dental and medical instruments comprising titanium
Endodontic instruments for use in performing root canal therapy on a tooth are disclosed. In one form, the instruments include an elongate shank having a cutting edge extending from a distal end of the shank along an axial length of the shank. The shank comprises a titanium alloy, and the shank is prepared by heat-treating the shank at a temperature above 25° C. in an atmosphere consisting essentially of a gas unreactive with the shank. In another form, the endodontic instruments have an elongate shank having a cutting edge extending from a distal end of the shank along an axial length of the shank. The shank consists essentially of a titanium alloy selected from alpha-titanium alloys, beta-titanium alloys, and alpha-beta-titanium alloys. The instruments solve the problems encountered when cleaning and enlarging a curved root canal.
US10023926B2 Method for the production of high-wear-resistance martensitic cast steel and steel with said characteristics
The invention relates to a method for the production of martensitic cast steel of high strength and excellent abrasion- and impact-wear resistance, intended for large parts used as anti-wear cladding in crushing and grinding mining operations, having a chemical composition, expressed in percentage by weight, of between 0.35˜0.55% C, 0.60˜1.30% Si, 0.60˜1.40% Mn, 4.5˜6.50% Cr, 0.0˜0.60% Ni, 0.30˜0.60% Mo, 0.0˜0.70% Cu, 0.010˜0.10% Al, 0.0˜0.10% Ti, 0.0˜0.10% Zr, 0.0˜0.050% Nb, less than 0.035% P, less than 0.035% S, less than 0.030% N, optionally 0.0005˜0.005% B, optionally 0.015˜0.080% rare earths, and the rest being iron. The method for the production of cast steel includes smelting, pouring and heat treatment. The smelting can be performed in an electric arc furnace with acidic or basic refractory or an electric induction furnace. Smelting in an electric arc furnace as a normal operation includes melting, oxygen insufflation, blocking, refining and deoxidation. Smelting in an electric induction furnace includes melting, refining, control of nitrogen in solution and deoxidation. The heat treatment comprises hardening in forced or still air depending on the thickness of the parts, followed by a tempering heat treatment. The cast steel of the invention demonstrates excellent resistance to abrasion-/impact-wear and a suitable chemical composition balance, with the addition of microalloying agents in order to obtain high hardenability and full curing in large cast parts, typically up to 14 inches thick, with Brinell hardness preferably around 630 BHN depending on the heat treatment conditions applied.
US10023925B2 Hot stamped article, method of producing hot stamped article, energy absorbing member, and method of producing energy absorbing member
A hot stamped article has a component composition containing, in terms of % by mass, 0.002% to 0.1% of C, 0.01% to 0.5% of Si, 0.5% to 2.5% of Mn+Cr, 0.1% or less of P, 0.01% or less of S, 0.05% or less of t-Al, 0.005% or less of N, and 0.0005% to 0.004% of B which is optionally contained in a case where the Mn+Cr is 1.0% or more, the remainder being Fe and unavoidable impurities. The hot stamped article has a microstructure composed of, in terms of an area ratio, 0% or more and less than 90% of martensite, 10% to 100% of bainite, and less than 0.5% of unavoidable inclusion structures, or a microstructure composed of, in terms of an area ratio, 99.5% to 100% of bainitic ferrite, and less than 0.5% of unavoidable inclusion structures.
US10023918B2 Methods for the diagnosis and treatment of inflammatory bowel disease
There is provided methods and compositions to diagnose, classify and treat inflammatory bowel disease including ulcerative colitis and Crohn's disease by measuring the levels of certain bacterial taxa and proteins collected from the gut.
US10023913B2 SR-BI as a predictor of elevated high density lipoprotein and cardiovascular disease
The present invention relates to the field of single nucleotide polymorphisms (SNPs) and uses therefore as a predictor of diseases and conditions. Specifically, the present invention provides methods and kits useful in determining whether a subject is at increased risk for developing a cardiovascular disease by screening for the presence of a SNP in the scavenger receptor class B type I (SR-BI) gene of a subject.
US10023909B2 Methods and kits for detection of methylation status
The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA.
US10023905B2 Polymerase driven NESA
The present invention relates to a novel method for detecting a target polynucleotide having a target sequence, comprising (a) exposing the target polynucleotide to an initiating oligonucleotide; (b) extending the initiating oligonucleotide with an extended sequence complementary to the target sequence; (c) ligating the initiating oligonucleotide sequence with the extended sequence to form a circular oligonucleotide having a nicking endonuclease (NE) recognition/cutting sequence; (d) exposing the circular oligonucleotide to a DNA polymerase and a DNA synthesis primer to synthesize DNA having a NE recognition sequence; (e) exposing the synthesized DNA to a probe having the NE recognition/cutting sequence to form a double stranded DNA having a full NE site; (f) exposing the double stranded DNA to a nicking endonuclease (NE) to cleave the probe; and (g) detecting the cleaved probe. The presence of the cleaved probe indicates the presence of the target polynucleotide.
US10023902B2 Methods for detecting enzyme activity using fluorescence lifetime imaging
Disclosed are methods of detecting enzymatic activity on a fluorophore-labeled substrate using by monitoring the fluorescence lifetime of the fluorophore.
US10023896B2 Cushioning device inspection system, a sampling device for inspection of a cushioning device and a cushioning device inspection method
A system for checking interior air contamination, the system including a sealed device including twin ports, a sampling device including a pump to extract at least some of the air from the interior of the sealed device, and a microbial detect to determine if the air contains contaminants. The twin ports are removably engageable with the sampling device to allow a circuit of air between the pump unit and the sealed device, such that air extracted from one of the twin ports by the pump is returned to the other of the twin ports, allowing no escape of the air to the environment. The sealed device is sealed to prevent, except through the twin ports, exterior air to flow into the sealed device and the air from the interior to flow out.
US10023892B2 Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
The present disclosure relates to glycoproteins, particularly monoclonal antibodies, comprising a glycoengineered Fc region, wherein said Fc region comprises an optimized N-glycan having the structure of Sia2(α2-6)Gal2GlcNAc2Man3GlcNAc2. The glycoengineered Fc region binds FcγRIIA or FcγRIIIA with a greater affinity, relative to comparable monoclonal antibodies comprising the wild-type Fc region. The monoclonal antibodies of the invention are particularly useful in preventing, treating, or ameliorating one or more symptoms associated with a disease, disorder, or infection where an enhanced efficacy of effector cell function (e.g., ADCC) mediated by FcγR is desired, e.g., cancer, autoimmune, infectious disease, and in enhancing the therapeutic efficacy of therapeutic antibodies the effect of which is mediated by ADCC.
US10023891B2 Process of chiral resolution of cyclic and acyclic acetates to enantiomerically pure (R)-alcohols
The patent discloses herein a process for the chiral resolution of racemic cyclic and acyclic acetates to obtain (R)-alcohol. Further, it discloses the resolution of racemic cyclic and acyclic acetates to obtain enantiomerically pure (R)-(−)-alcohol as single enantiomer through fungal catalyzed deacylation in single fermentation, wherein fungal strains are F. proliferatum.
US10023889B2 Microbial approach for the production of 5-hydroxytryptophan
5-hydroxytryptophan (5-HTP), a precursor of serotonin, is produced in a microbial host cell. A modified bacterial phenylalanine 4-hydroxylase (P4H) catalyzes the tryptophan 5-hydroxylation reaction. Optionally the host cell includes a cofactor regeneration mechanism, allowing continuous production of 5-HTP without supplementation of exogenous cofactors.
US10023882B1 Hetero-oligomers of (S)-carbonyl reductases and their applications in catalyzing reduction of polyphenyl ketones
Provided are novel hetero-oligomers of (S)-carbonyl reductases and their application in catalyzing the reduction of polyphenyl ketones. Also provided are recombinant strains expressing hetero-oligomers of SCR/SCR2 or SCR2/SCR3, which can catalyze the reduction of polyphenyl ketones. The hetero-oligomer of SCR/SCR2 is capable of catalyzing 2,4-dichlorobenzophenone, 2-naphthalenone and [(E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester (Keto Easter M) with a specific activity of 4.55 U/mg, 2.43 U/mg and 0.86 U/mg, respectively. The hetero-oligomer of SCR2/SCR3 is capable of catalyzing 2,4-dichlorobenzophenone and [(E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester (Keto Easter M) with a specific activity of 4.42 U/mg and 1.21 U/mg, respectively. No catalyzing activities for reducing polyphenyl ketones were detected in the naturally existing homo-oligomers of SCR, SCR2 or SCR3, which can catalyze the reduction of monobenzoic cyclic compounds. The invention expands the substrate spectrum of natural (S)-carbonyl reductases (SCR, SCR2 and SCR3) and provides a novel type of oxidoreductases for catalyzing the reduction of polyphenyl ketones.
US10023878B2 Method for the alteration of plants using CLE polypeptides/peptides
The present invention relates to altering the biomass and/or structure of a plant, in order to maximize its potential as a source of feedstock or increase its potential as a feedstock for the paper industry. CLE41 and/or CLE42 are used to manipulate growth and structure of the vascular tissue of the plant. The present invention also provides plants in which the levels of CLE41 and/or CLE42 are increased compared to those of a native plant grown under identical conditions, and parts of such plants. Also provided are methods for using such plants or plant parts in the production of plant derived products such as paper or biofuels.
US10023876B2 Engineered pesticidal proteins
Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.
US10023874B2 Herbicide tolerance genes and methods of use thereof
Polypeptides and recombinant DNA molecules useful for conferring tolerance to AOPP herbicides, phenoxy acid herbicides, and pyridinyloxy acid herbicides are provided in the present invention, as well as herbicide tolerant transgenic plants, seeds, cells, and plant parts containing the recombinant DNA molecules, as well as methods of using the same.
US10023869B2 Bio-sensor for the detection of small molecules
This present invention provides methods for the detection of small molecules in samples comprising the steps a) coupling a nanoparticle (NP) or microparticle (MP) to an aptamer specific for the small molecule to be detected to form a NP-aptamer conjugate b) contacting the NP-aptamer conjugate with the sample; and c) detecting a change in the size, surface potential, or mobility of the NP-aptamer conjugate, wherein the change is indicative of the presence of the small molecule. The present invention also provides for and a biosensor comprising nanoparticles coupled to aptamers to provide nanoparticle aptamer-conjugates (NP-aptamer).
US10023868B2 MiRNA for treating diseases and conditions associated with neo-angiogenesis
The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
US10023866B2 Compositions and methods for inhibition of nucleic acids function
The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.
US10023862B2 Organic compositions to treat beta-catenin-related diseases
The present disclosure relates to RNAi agents useful in methods of treating Beta-Catenin-related diseases such as adenomatous polyposis of the colon, colorectal cancer, basal cell carcinoma, breast cancer, kidney cancer, Wilms tumors, medulloblastoma, ovarian cancer, adrenocortical tumors, gastric cancer, liver cancer, melanoma, pancreatic cancers, prostate cancer, renal cancer, ectopic teeth and taste papillae, skin cancer, pilomatrixoma, anaplastic thyroid carcinoma, and uterine carcinosarcoma, oligodontia, osteoporosis, ageing, degenerative diseases, bedsores, chronic wounds and impaired wound healing, and similar and related diseases, using a therapeutically effective amount of a RNAi agent to Beta-Catenin.
US10023856B2 Enzyme composition for DNA end repair, adenylation, phosphorylation
Enzyme compositions and their method of use that provide ready-to-use master mixtures. The compositions comprise a modified thermophilic DNA polymerase lacking 5′-3′ and 3′-5′ exonuclease activity premixed with T4 DNA polymerase, Klenow fragment and T4 polynucleotide kinase and all other necessary components, including reaction buffer and nucleoside triphosphates, required to perform DNA blunting, phosphorylation, and single nucleotide extension reactions in one tube and in two steps. Among other benefits, the mixture of different enzymes, buffers and nucleoside triphosphates is stable during prolonged storage.
US10023855B2 Fusion protein comprising C-terminal domain of RET protein and use thereof as a diagnosing marker
A fusion protein including N-terminal domain of a fusion partner at N-terminal and C-terminal domain of RET protein at C-terminal, a fusion gene encoding the fusion protein, and a use of the fusion protein or the fusion gene as a diagnosing marker for a cancer, are provided.
US10023853B1 Engineered nucleic-acid targeting nucleic acids
The present disclosure provides engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof. Nucleic acid sequences encoding the engineered cross-type-nucleic-acid targeting nucleic acids, as well as expression cassettes, vectors and cells comprising such nucleic acid sequences, are described. Also, methods are disclosed for making and using the engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof.
US10023851B2 Compositions and methods comprising a lipolytic enzyme variant
The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
US10023850B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US10023847B2 Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination
The invention describes new peptides containing epitopes recognized by CD4+ natural killer T (NKT) cells for increasing activity for use in infectious diseases, autoimmune diseases, immune reaction to administration of allofactors, allergic diseases, therapy of tumors, prevention of graft rejection and prevention of immunization against viral proteins used in gene therapy or gene vaccination.
US10023842B2 Endothelial and endothelial like cells produced from fibroblasts and uses related thereto
This disclosure relates to endothelial or endothelial like cells cultured from fibroblasts exposed to transcription factor ETV2. In certain embodiments, the disclosure relates to methods of producing endothelial or endothelial like cells comprising exposing fibroblasts with ETV2 under conditions such that the fibroblasts are modified to form a pool of cells expressing increased levels of endothelium surface markers compared to the fibroblasts. In certain embodiments, the disclosure relates to using endothelial like cells reported herein for the treatment of vascular, cardiac, and wound healing indications.
US10023841B2 Methods and compositions for treating breast cancer with dendritic cell vaccines
Disclosed are compositions and methods for treatment of breast cancer. Disclosed methods and compositions include dendritic cells loaded with cyclin B1 and WT-1 peptide antigens for immunotherapy. These dendritic cell vaccines are administered alone or in combination with other cancer therapies to improve outcomes. Disclosed methods also involve the use of therapeutic agents, such as anakinra, that block the IL-1 inflammation pathway. These agents are used in combination with chemotherapy and/or immunotherapy in treating breast cancer.
US10023838B2 Method of inducing differentiation from pluripotent stem cells to germ cells
This invention provides a method of producing a primordial germ cell-like cell (PGCLC) from an epiblast isolated from an embryo or an epiblast-like cell (EpiLC) induced from a pluripotent stem cell (PSC), which comprises allowing the epiblast or EpiLC to express exogenous transcription factor(s) selected from the group consisting of: (i) Blimp1, Prdm14 and Tfap2c; ii) Blimp1 and Prdm14; (iii) Blimp1 and Tfap2c; (iv) Prdm14 and Tfap2c; and (v) Prdm14; thereby inducing the epiblast or EpiLC into a PGC state without acquiring transient mesodermal program.
US10023837B2 Materials and methods for identifying and using yeast strains that metabolize pentose sugars in the presence of D-glucose
Disclosed herein are materials and methods for creating and/or isolating variants of yeasts especially variants of Saccharomyces cerevisiae that can grow on sugars other than D-glucose in the presence of amounts of 2-deoxy-glucose and or D-glucose that inhibit most strains of yeast from growing on sugars other than D-glucose. Selection media that can be used to isolate such variants include pentose sugars such as D-xylose, L-glutamine and 2-deoxy-glucose. Mutations in the Grr1 and Red genes in some strains also produce variants that can grow on sugars including the pentose D-xylose in the presence of 2-deoxy-glucose.
US10023835B2 Method of adjusting the conditions of biological processes and a reactor for carrying out the method
The method of pH controlling during electrolytic fermentation processes of the organic substrates includes placing the biological and chemical reagents in a fermentation tank, placing the electrodes powered by the direct current in the fermentation tank chambers, switching on the constant voltage initiating electrolytic processes with a value from 0.1 to 50 V, generating H+ or OH− ions around the electrodes, reading the data from the glass electrode, changing the power parameters of electrodes, depending on the set pH value of the reaction medium, and starting a pump metering the liquid from the auxiliary chamber into the fermentation tank chamber through a dispensing connector. The object of the invention is also the reactor for carrying out this method.
US10023834B2 Culture apparatus
A culture apparatus that cultivates a culture, which includes an outer case, an inner case configured with metal plates inside the outer case, a heater outside the inner case, and a door, which opens/closes an opening formed in front faces of the inner cases, includes: shelf rests on which side parts of a bottom plate of a shelf are to be placed, the shelf rests formed by pressing on side plates of the inner case; and a heat transfer sheet attached to an outer surface of at least one of the side plates and configured to transfer heat of the heater to the inner case, the heat transfer sheet including slits, intermittently formed, to bend the sheet to depressions of the outer surface of the side plate at positions corresponding to the shelf rests, after the heat transfer sheet is attached to the outer surface.
US10023833B2 Temperature sensor means and a bioreactor system comprising a temperature sensor means
A temperature sensor means comprising a thermally conducting layer arranged to face the surface to be measured, a thermally insulating layer attached to the thermally conducting layer on the opposite side to the surface to be measured, a temperature sensor provided between the thermally conducting layer and the thermally insulating layer and being completely surrounded on all its sides by either the thermally conducting or the thermally insulating layers.
US10023832B2 Interconnections of multiple perfused engineered tissue constructs and microbioreactors, multi-microformulators and applications of the same
The invention relates to a system of fluidic valves and pumps and associated fluidic channels integratable into a bio-object microfluidics module. The module includes input and output buses; upstream and downstream interconnection bus control valves (CVs) coupled to the input and output buses, respectively. It may include arterial, venous, wash and waste bus lines, each connecting between the upstream and downstream interconnection bus CVs. It may also include an input CV connecting to the arterial bus line, upstream interconnection bus CV, bio-object and inlets, and an output CV connecting to the bio-object, input CV, downstream interconnection bus CV and outlets; and a pump connecting between the input CV and bio-object. The system can be arranged to provide MicroFormulator functionality enabling precise mixtures of drugs, chemicals, or biochemicals to be delivered in a time-dependent fashion to biological entities housed in individual wells or chambers.
US10023829B1 Blue whiskey and method for making blue-colored whiskey
The present invention is directed to a method of preparing a blue-colored whiskey by mixing methylene blue, pure alcohol and distilled water. This process creates a staining solution and would allow the staining solution be aged in a cask prior to adding the whiskey into the cask. The stained cask colors the whiskey solution. This whiskey making method is designed to generate blue whiskey in which the color of the distillate is not directly altered. Further, this method provides a new way of presenting such beverages to potential customers in a pleasing way that could potentially enhance market share, and provides a new method to change beverages into new and unusual colors which may provide fun and additional marketing/branding opportunities.
US10023827B2 Cleaning composition for semiconductor substrate and cleaning method
A cleaning composition for a semiconductor substrate contains a solvent, and a polymer that includes a fluorine atom, a silicon atom or a combination thereof. The content of water in the solvent is preferably no greater than 20% by mass. The cleaning composition preferably further contains an organic acid which is a non-polymeric acid. The organic acid is preferably a polyhydric carboxylic acid. The acid dissociation constant of the polymer is preferably less than that of the organic acid. The solubility of the organic acid in water at 25° C. is preferably no less than 5% by mass. The organic acid is preferably a solid at 25° C.
US10023824B2 Lubricant composition
A lubricant composition and a method of lubricating off-road vehicles and/or machinery. The lubricant composition includes (i) a base oil, (ii) at least one ashless component (A) having the structure P(═S)(SR1)(OR2)(OR3), wherein R1, R2 and R3 are independently selected form the group consisting of alkyl, aryl, alkylaryl, cycloalkyl, alcohol, carboxylic acid and ester having 1 to 24 carbon atoms; and (iii) at least one component (B) being a metal dialkyl dithio phosphate salt. The total of ashless components (A) provides to the lubricant composition from 0.010 to 0.080 wt. % phosphorus based on the total weight of the lubricant composition and the total of components (B) provides to the lubricant composition from 0.010 to 0.080 wt. % phosphorus based on the total weight of the lubricant composition.
US10023822B2 Production of base oils from petrolatum
Methods are provided for producing lubricant base oils from petrolatum. After solvent dewaxing of a brightstock raffinate to form a brightstock base oil, petrolatum is generated as a side product. The petrolatum can be hydroprocessed to form base oils in high yield. The base oils formed from hydroprocessing of petrolatum have an unexpected pour point relationship. For a typical lubricant oil feedstock, the pour point of the base oils generated from the feedstock increases with the viscosity of the base oil. By contrast, lubricant base oils formed from hydroprocessing of petrolatum have a relatively flat pour point relationship, and some of the higher viscosity base oils unexpectedly have lower pour points than lower viscosity base oils generated from the same petrolatum feed. The base oils from petrolatum are also unusual in yielding both high viscosity and high viscosity index and can be generated while maintaining a high yield.
US10023820B2 Device and method for producing substitute natural gas and network comprising same
A device includes a gasifier to produce a gaseous compound from a biomass. The gasifier includes inlets for the biomass and for an oxidizing agent and an outlet for the gaseous compound including carbon monoxide. A first methanation unit to methanate the carbon monoxide to produce a substitute natural gas exiting the gasifier. The first methanation unit includes at least one inlet for water and an inlet for the gaseous compound coming from the gasifier. A second methanation unit to methanate the carbon dioxide to produce the substitute natural gas. The second methanation unit includes at least one inlet for water and one inlet for the carbon dioxide from the first methanation unit. A dihydrogen producing unit to produce dihydrogen from water and electric current. The dihydrogen producing unit includes an electrical power supply, an inlet for water and an outlet for dihydrogen supplying the second methanation unit.
US10023815B2 Process for producing high octane gasoline component from renewable raw material
This invention relates generally to a process for producing gasoline component. More particularly, the invention relates to a process for producing high octane gasoline component using renewable raw material as an additional feedstock. Further, the invention provides a gasoline fuel component having high biocontent obtainable from co-processing of vacuum gas oil and renewable feed stock material in a catalytic cracking unit.
US10023813B2 Process for selective deep hydrodesulfurization of a hydrocarbon feedstock using an unsupported nanocatalyst made by laser pyrolysis
A process for producing an unsupported molybdenum sulfide nanocatalyst comprising atomizing a molybdenum oxide solution to form a molybdenum oxide aerosol, pyrolyzing the molybdenum oxide aerosol with a laser beam to form the unsupported molybdenum-based nanocatalyst, and pre-sulfiding at least a portion of the unsupported molybdenum-based nanocatalyst to form an unsupported molybdenum sulfide nanocatalyst, wherein the unsupported molybdenum-based nanocatalyst, the unsupported molybdenum sulfide catalyst or both are in the form of nanoparticles with a diameter of 1-10 nm and in a distorted rutile crystalline structure. A method of selective deep hydrodesulfurization whereby a hydrocarbon feedstock having at least one sulfur-containing component and at least one hydrocarbon is contacted with the unsupported molybdenum sulfide nanocatalyst.
US10023811B2 Integrated gas oil separation plant for crude oil and natural gas processing
Systems and methods of integrated gas oil separation are disclosed. Systems include a high pressure production trap (HPPT), a low pressure production trap (LPPT), a low pressure degassing tank (LPDT), a first knockout drum (KOD) fluidly coupled to the LPDT and operable to accept an atmospheric pressure off-gas from the LPDT, an atmospheric pressure compressor fluidly coupled to the first KOD and operable to compress the atmospheric pressure off-gas to introduce the atmospheric pressure off-gas from the LPDT into the LPPT inlet feed stream, a second KOD fluidly coupled to the LPPT and operable to accept a low pressure off-gas from the LPPT, and a low pressure compressor fluidly coupled to the second KOD and operable to compress the low pressure off-gas to introduce the low pressure off-gas from the LPPT into the crude oil inlet feed stream.
US10023807B2 Discriminate mass transfer in a wet oxidation system
A method for treatment of a carbonaceous feedstock such as coal or biomass. The method comprises adsorbing an oxidizing agent selected from an oxygen-containing gas, hydrogen peroxide, ozone and oxidizing acids from a liquid phase of an aqueous mixture comprising water and the carbonaceous feedstock onto the carbonaceous feedstock to produce an aqueous mixture with the liquid phase having a reduced content of the oxidizing agent and the carbonaceous feedstock having oxidizing agent adsorbed on a surface thereof, and heating this aqueous mixture to a temperature and for a sufficient time to partially oxidize and solubilize at least a portion of the carbonaceous feedstock. The reaction products may be chemically or physically separated, recycled to the heating step and/or subjected to microbial digestion in order to generate one or more desirable products from the carbonaceous feedstock. The solid portion of the reaction products may be further processed to be used in the paper industry.
US10023804B2 System and process for converting whole tires and other solid carbon materials into reclaimable and reusable components
A system and method of converting tires or other solid carbon based material is disclosed, including providing a chamber, feeding the solid carbon based material into the chamber, rotating the chamber, heating and reducing the material in the chamber, collecting solid residue from the chamber, collecting vapor from the chamber, and converting vapor collected from the chamber to a liquid. In an embodiment, the material includes a whole tire. The tire is heated in the chamber causing the tire to collapse and liquefy, exposing the metal in the tire which aids in grinding the carbon material in the tire as it tumbles, collecting solid residue, for example tire carbons, and collecting vapor, for example vaporized oil, and benzene and methane gas from the chamber and converting the oil. The chamber may be heated to a temperature from about 350° F. to about 1100° F. using gases reclaimed from the material.
US10023803B2 Method for performing pyrolysis and a pyrolysis apparatus
Solid fuel in the form of particles is supplied to a pyrolyzer, and pyrolysis conditions are maintained in the pyrolyzer for separating condensable gaseous substances from the fuel. Heat required by the pyrolysis conditions is supplied at least partly with solid fluidized bed material which passes through the pyrolyzer simultaneously as it is fluidized by fluidizing gas in the pyrolyzer. Condensable gaseous substances separated from the fuel are conveyed from the pyrolyzer to a condenser, in which they are separated as so-called pyrolysis oil in liquid form, and solid fluidized bed material taken from the pyrolyzer and containing combustible pyrolysis residue originating from the fuel is circulated through a gasifier, in which product gas, which is burnt in a boiler or a kiln, is formed from the pyrolysis residue.
US10023802B2 Alignment film material and method for producing alignment film
An alignment film material and a method of producing an alignment film are described. The alignment film material has polyimide and crosslinked polymer. The crosslinked polymer is formed from a first component through a crosslinking reaction. A crosslink density of the alignment film can be enhanced without additionally adding a catalyst, so as to increase a hardness of the alignment film.
US10023801B2 Polymerizable-compound-containing liquid crystal composition and liquid crystal display element using same
There is provided a liquid crystal display device of a PSA type or the like that uses the polymerizable compound-containing liquid crystal composition, having a sufficiently fast response speed, capable of 3D displaying. Uniform and stable orientation control can be obtained at a lower energy cost. Provided are the polymerizable compound-containing liquid crystal composition containing one or two or more polymerizable compounds represented by general formula (M) as the first component, and containing one or two or more compounds represented by general formula (Na), general formula (Nb), or general formula (Nc) having a naphthalene unit as the second component. The liquid crystal display device uses the same.
US10023800B2 Composition for manufacturing optical elements with negative optical dispersion, and optically anisotropic body manufactured therefrom
The present invention relates to a composition for manufacturing optical elements with negative optical dispersion, and an optically anisotropic body prepared therefrom. According to the present invention, the optically anisotropic body showing stable reverse wavelength dispersion can be prepared more simply by using the composition for optical elements, and it is possible to apply the same to liquid crystal display devices as an optical film such as a thin-layer broadband λ/4 plate.
US10023799B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device
To provide a liquid crystal compound satisfying at least one of physical properties such as high stability to light, a high clearing point, a low minimum temperature of a liquid crystal phase, small viscosity, suitable optical anisotropy, large dielectric anisotropy, a large dielectric constant in a minor axis direction, a suitable elastic constant and excellent compatibility; a liquid crystal composition containing the compound; and a liquid crystal display device including the composition. The compound is represented by formula (1):
US10023798B2 Liquid crystal compositions comprising mesogenic compounds, and devices for high-frequency thechnology
Disclosed are novel mesogenic compounds, liquid crystal compositions (liquid-crystalline media) comprising them and suitable for high-frequency technology, and high-frequency devices using them, such as phase shifters, antennas, tunable filters, switching devices, e.g. operated in the microwave region, to a process for preparing the compositions. The liquid crystal compositions have high optical anisotropy, a positive dielectric anisotropy and a wide temperature range of nematic phases.
US10023797B2 Liquid composition for etching oxides comprising indium, zinc, tin, and oxygen and etching method
Provided is a liquid etching composition that etches an oxide comprising indium, zinc, tin and oxygen at a preferable etching rate, without the etching rate being changed much along with the dissolution of the oxide, and with no substantial generation of deposit, and corrodes wiring materials at such a low level to be ignorable. The present invention uses a liquid etching composition comprising (A) at least one selected from the group consisting of sulfuric acid, methanesulfonic acid, and a salt of any of these acids; and water; the liquid etching composition having a pH value of −1 to 3.
US10023796B2 Illumination system comprising composite monolithic ceramic luminescence converter
An illumination system comprising a radiation source and a monolithic ceramic luminescence converter comprising a composite material of at least one luminescent compound, and at least one non-luminescent compound, wherein the material of the non-luminescent compound comprises silicon and nitrogen, is advantageously used, when the luminescent compound comprises an rare-earth metal-activated host compound also comprising silicon and nitrogen. Shared chemical characteristics of the luminescent compound and the non-luminescent material improve phase assemblage, thermal and optical behavior. The invention relates also to a composite monolithic ceramic luminescence converter.
US10023795B2 Ceramic composite systems and method
Embodiments of the invention provide a ceramic composites and synthesis methods that include providing a plurality of nanoparticles with at least one first rare-earth single-crystal compound, and mixing the plurality of nanoparticles with at least one ceramic material and at least one ceramic binder including at least one solvent. The method further includes preparing a ceramic green-body from the mixture, and sintering the ceramic green-body to form a ceramic composite of a polycrystalline ceramic with a plurality of embedded single-crystal nanorods. The embedded single-crystal nanorods include at least one second rare-earth single crystal compound. The at least one second rare-earth single crystal compound can include or be derived from the at least one first rare-earth single crystal compound.
US10023793B2 Particles with quantum dots and method of making the same
A marker composition and a package using same. The marker composition can include retroreflective particles and a dispersion medium, the blending ratio of the retroreflective particles being from 50 to 90 mass % on the basis of the total marker composition.
US10023791B1 System and method of coating a proppant
A system for adding dust control solution to a vertically falling first stream of a substantially dry particulate proppant, where the first stream has effective diameter, the system including a stationary, generally horizontal, deflector plate with drop-off edge, the plate mounted into the stream whereby the proppant collides with the plate and cascades from the plate around the drop-off edge to create a second stream of the particulate proppant having the general shape of the drop-off edge with a stream thickness and nozzles for spraying dust control solution into the second stream.
US10023790B1 Dust free proppant and method of making same
A long term dust free proppant comprising a mass of free flowing particles, where the particles are coated with a dust suppression solution containing 90 to 99.5 percent by weight water, 0.05 to 3.0 percent by weight a soluble polymer and an added, small amount of a surfactant. The mass has a very low dosage of the solution so the mass has a moisture content of less than 0.30 percent by weight. Preferably the solution is applied to the particles by an air mist jet.
US10023789B2 Enhancing complex fracture networks in subterranean formations
Methods of introducing into a subterranean formation a series of treatment fluids comprising one of micro-proppant particulates, micro-degradable particulates, branch-proppant particulates, branch-degradable particulates, main-proppant particulates, and main-degradable particulates and placing the particulates into portions of microfracture(s), branch fracture(s), and main fracture(s) to increase fracture complexity of a fracture network in the subterranean formation.
US10023787B2 Surfactant selection methods for fluid recovery in subterranean formations
Methods for selecting a surfactant for treating a subterranean formation based on the performance of the surfactant and the characteristics of the subterranean formation and the treatment fluids that may be used to treat that formation are provided. In one embodiment, the method may comprise providing a treatment fluid, formation materials, hydrocarbon, and a plurality of surfactants, wherein the hydrocarbon is acquired from a subterranean formation; selecting at least two surfactants from the plurality of surfactants by determining whether each of the plurality of surfactants separates a mixture of the treatment fluid and the hydrocarbon; and selecting at least one surfactant from the at least two surfactants by determining whether the hydrocarbon displaces the treatment fluid from the formation materials in the presence of each of the at least two surfactants.
US10023786B2 Method for making particulate slurries and particulate slurry compositions
An aqueous slurry composition for use in industries such as the petroleum and pipeline industries includes a particulate, an aqueous liquid and a chemical compound that renders the particulate surface extremely hydrophobic. The slurry is produced by rendering the surface of the particulate extremely hydrophobic during or before making the slurry.
US10023785B2 Thixotropic agents and methods of use
A thixotropic agent comprised of a gel which is comprised of a polymeric organic material cross-linked with certain boehmite aluminas having a crystallite size of less than about 100 Å as measured on the 120 plane.
US10023780B2 2,3,3,3-tetrafluoropropene compositions having improved miscibility
The use of an alcoholic compound to improve the miscibility of ammonia with 2,3,3,3-tetrafluoropropene, as well as to compositions of ammonia, 2,3,3,3-tetrafluoropropene and an alcoholic compound, and the use thereof, in particular in heat-transfer applications. A composition including 2,3,3,3-tetrafluoropropene, ammonia and an alcoholic compound having a melting point less than or equal to 0° C.
US10023777B2 Adhesive compositions and methods of adhering articles together
An adhesive composition containing cottonseed protein, and one or more of the following components: (i) soy protein, (ii) a polysaccharide, and (iii) at least one modifier selected from a carboxylic acid, a dicarboxylic acid, a phosphorus-containing acid or ester, a cationic amino acid, a quaternary ammonium salt, or mixtures thereof.
US10023773B2 Adhesives, UV-crosslinkable PSAs and bonding agents with UV-crosslinked PSAs
Adhesives and pressure-sensitive adhesives comprising polymerization products of acrylates, the adhesives being meltable and comprising polymerization products of esters of (meth)acrylic acid and (meth)acrylic acid, the polymerization product having a molecular weight Mn of greater than 50 000 g/mol and Mw of greater than 500 000 g/mol.
US10023772B2 Pressure sensitive adhesive composition
Provided are a pressure-sensitive adhesive composition, a pressure-sensitive adhesive optical laminate, a pressure-sensitive adhesive polarizing plate and a display device. The pressure-sensitive adhesive composition offers a pressure-sensitive adhesive that has excellent durability and processability in manufacturing due to increased hardness even when the pressure-sensitive adhesive layer is formed thinner than a typical adhesive composition, and that can prevent a pressure mark and leakage of the pressure-sensitive adhesive, as well as a bending problem generated when applied on an optical member such as a polarizing plate, etc.
US10023771B2 Hot melt adhesive composition
The present disclosure provides a composition. In an embodiment an adhesive composition is provided and includes A) a propylene based plastomer or elastomer (PBPE) comprising up to 10 wt % units derived from ethylene and having (i) a Koenig B-value less than 1.0; (ii) a total unsaturation per mole of propylene from 0.01% to 0.03%; (iii) a density from 0.870 g/cc to 0.890 g/cc; (iv) a melt viscosity at 177° C. from 800 mPa·s to 11,000 mPa·s; and (v) a weight average molecular weight from 20,000 to 50,000 g/mol; B) a tackifier; and C) a wax.
US10023768B2 Article comprising pressure-sensitive adhesive stripes
An article including a release liner with an adhesive layer disposed thereon, the adhesive layer including a plurality of stripes of a first pressure-sensitive adhesive and of a second pressure-sensitive adhesive, arranged in a generally alternating pattern. The first pressure-sensitive adhesive is a silicone-based pressure-sensitive adhesive that includes a silicone block copolymer elastomer comprising hard segments that each comprise at least one polar moiety, and the second pressure-sensitive adhesive is an organic polymeric pressure-sensitive adhesive.
US10023762B2 Epoxy resin-based gel coat for surface finishing of components made of fibre-reinforced plastics
A composition for the manufacture of a gelcoat includes a main component and a curing component. The main component comprises at least one epoxide resin selected from the group consisting of glycidyl ethers of bisphenol A, glycidyl ethers of bisphenol F, trimethylolpropane triglycidyl ethers, and mixtures thereof, and up to 5 wt.-% of at least one of a filler and a pigment based on a total weight of the main component. The curing component comprises at least one cycloaliphatic amine. The main component or the curing component further comprises at least one polytetrahydrofurane polyol.
US10023761B2 Coatings for plastic substrates
Disclosed is a coating composition comprising a resinous binder prepared from a reaction mixture comprising (a) a first component; (b) a second component; and (c) a third component comprising a block copolymer having (i) a first block comprising units having functional groups reactive with at least one of the first and second components and (ii) a second block comprising units having functional groups that promote adhesion to a polymeric substrate, provided that the first component, the second component, and the block copolymer differ from each other. The block copolymer may also be used as an additive in a coating composition.
US10023755B2 Solvent-based and water-based carbon nanotube inks with removable additives
In accordance with some embodiments, compositions and methods for forming solvent-based and water-based carbon nanotubes inks with removable additives are provided. In some embodiments, an ink composition is provided that includes a plurality of carbon nanotubes, a solvent, and a triazole-based removable additive, where the plurality of carbon nanotubes are dispersed within the solvent and wherein the triazole-based removable additive stabilizes the plurality of carbon nanotubes that are dispersed in the solvent.
US10023753B1 Product for reconditioning a surface and methods for reconditioning a surface
Disclosed is a product comprised of a urethane reducer and an oil.
US10023752B2 Conductive material and substrate
The present invention provides a conductive material including: (A) a π-conjugated polymer, (B) a dopant polymer which contains one or more repeating units selected from “a1” to “a4” respectively shown by the following general formula (1) and has a weight-average molecular weight in the range of 1,000 to 500,000, and (C) one or more salts selected from the group consisting of a monovalent copper salt of carboxylic acid, a monovalent copper salt of β-diketone, and a monovalent copper salt of β-ketoester. There can be provided a conductive material that has excellent film-formability and also can form a conductive film having high transparency and conductivity, superior flexibility and flatness when the film is formed from the material.
US10023750B2 Aqueous hydrophilizing surface treatment agent, hydrophilic coating film and hydrophilizing surface treatment method
A water-based surface treatment agent includes an organic-inorganic silicon compound (A) and inorganic particle (B), wherein the organic-inorganic silicon compound (A) is adapted to be a compound that is obtained by mixing a colloidal silica (C) and an organoalkoxysilane (D). In this regard, the ratio (MB/MA) between the solid content mass MA of the organic-inorganic silicon compound (A) and the solid content mass MB of the inorganic particle (B) preferably falls within the range from 0.2 or more and 2.0 or less, the average particle size of the organic-inorganic silicon compound (A) preferably falls within the range of 3 nm or more and 500 nm or less. In addition, the average particle size of the inorganic particle (B) preferably falls within the range of 10 nm or more and 600 nm or less.
US10023747B2 Active energy ray curable aqueous emulsions
The present invention relates to an aqueous radiation curable composition comprising: (I) at least one ethylenically unsaturated compound (A), and (II) at least one emulsifier (B) comprising alternating polyalkylene oxide segments, wherein said emulsifier optionally bears one or more groups selected from alkyl groups, aryl groups hydroxyl groups and/or ethylenically unsaturated groups, and wherein said emulsifier (B) has an HLB value of at least 4.5, preferably at least 7. The compositions of the invention are particularly suited for the manufacture of sprayable eco-friendly hardcoats, but they are also suitable for the making of inks, overprint varnishes and adhesives, alone or in combination with e.g. a water-borne polymer dispersion.
US10023742B2 Disperse azo dyes, a process for the preparation thereof and the use thereof
The present invention relates to azo dyes of formula wherein R1 denotes C1-C12 alkyl which is unsubstituted or substituted by one or more C1-C12 alkoxy groups, hydroxyl groups, amino groups, cyano groups or halogen atoms and which may be interrupted one or more times by the radical —O—, —S—, —NR4—, —COO— or —OOC—; R4 is hydrogen or C1-C12 alkyl; either R2 is cyano and R3 is halogen or R2 is halogen and R3 is cyano; and Ar represents a carbocyclic or heterocyclic aromatic radical, to the process for the preparation thereof, to mixtures containing said dyes and to the use thereof in dyeing or printing semi-synthetic and especially synthetic hydrophobic fiber materials, more especially textile materials.
US10023739B2 Semi-crystalline build materials
A polymeric material includes a semi-crystalline polymer and a secondary material wherein when the secondary material is combined with the semi-crystalline polymer to form a blend having an enthalpy that is between about 2 J/g heat of fusion and about 80% of the heat of fusion of the neat semi-crystalline material, as measured by differential scanning calorimetry (DSC) when cooling from a melting temperature to a hot crystalline temperature at a rate of 10° C./min.
US10023737B2 Molding material, molding method using same, method for producing molding material, and method for producing fiber-reinforced composite material
Provided is a molding material comprising a composite of 1 to 50 wt % of a continuous reinforcing fiber bundle (A) and 0.1 to 20 wt % of a poly (phenylene ether ether ketone) oligomer (B); and 30 to 98.9 wt % of a thermoplastic resin (C) adhering to the composite, wherein the component (B) has a melting point of not higher than 270° C. Also provided are a method for molding the molding material, a method for producing the molding material, and a method for producing a fiber-reinforced composite material.A molded article having high heat resistance and dynamic properties can be easily produced without impairing the economic efficiency and productivity during the process for producing a molding material. In addition, a fiber-reinforced composite material can be produced with more ease and high productivity.
US10023728B2 Latex composition for dip-forming including carboxylic acid modified-nitrile based copolymer latex and dip-formed article prepared therefrom
The present invention relates to a latex composition for dip-forming including two different types of carboxylic acid modified-nitrile based copolymer latex, and a dip-formed article prepared therefrom having excellent durability for sweat, and having high tensile strength and elongation percentage. Accordingly, the latex composition for dip-forming has excellent tensile strength, elongation percentage, stress and durability, and is useful in industries requiring these, for example, a rubber glove industry and the like.
US10023727B2 Composition for rubber bushing having vibration isolation and fatigue endurance characteristics
A rubber bushing composition and an automotive bushing manufactured by molding the composition are provided. The rubber bushing composition has advanced vibration isolation and fatigue endurance conflicting with each other.
US10023725B2 Nanocomposites containing nonspherical silica nanoparticles, composites, articles, and methods of making same
A nanocomposite is provided including nonspherical silica nanoparticles dispersed in a curable resin or a curing agent, where the nanocomposite contains less than 2% by weight solvent. A composite is also provided including from about 4 to 70 weight percent of nonspherical silica nanoparticles dispersed in a cured resin, and a filler embedded in the cured resin. Further, a method of preparing a nanoparticle-containing curable resin system is provided including mixing from 10 to 70 weight percent of aggregated silica nanoparticles with a curable resin and optionally a dispersant, a catalyst, a diluent, a surface treatment agent, and/or a curing agent, to form a mixture. The mixture contains less than 2% by weight solvent. The method also includes milling the mixture in an immersion mill containing milling media to form a milled resin system including nonspherical silica nanoparticles dispersed in the curable resin.
US10023716B2 Liquid crystalline composition having a dark black color
A shaped part that is formed from a polymer composition that contains a liquid crystalline polymer and a black pigment is provided. By selectively controlling the type and relative concentration of these components, the polymer composition and shaped parts formed therefrom can have a dark black appearance, and yet still exhibit good thermal and mechanical properties at high temperatures.
US10023714B2 Porous polymeric separation material
The present invention relates to a mesoporous polymeric separation material comprising one or more functional groups bound to metal ions from Cu, Zn, Ag, or Pd. Methods of producing the material, as well as methods for its preparation, and use of said material in separation of pesticides from food or feed products is disclosed.
US10023713B2 Hollow nano-particles and method thereof
The invention provides a hollow nano-particle comprising a crosslinked shell and a void core; and a preparation method thereof. The hollow nano-particle may be used in rubber composition, tire product, and pharmaceutical delivery system etc.
US10023710B2 Polymeric material for an insulated container
A formulation includes a polymeric material, a nucleating agent, a blowing, and a surface active agent. The formulation can be used to form a container.
US10023709B2 Multiporous hollow-fiber membrane and process for producing multiporous hollow-fiber membrane
The present invention relates to a multiporous hollow-fiber membrane containing a thermoplastic resin, in which an aspect ratio of outer surface pores is 10 or more, an aspect ratio of inner surface pores is 1 to 5, and a thickness of a polymer backbone forming the outer surface pores is 1 μm to 20 μm.
US10023704B2 Use of a fine aqueous polymer dipersion for the impregnation of natural fibres
The use of an aqueous polymer dispersion including at least one amorphous polymer having a Tg varying between 55° C. and 175° C. or a semi-crystalline polymer having a melting point varying between 70° C. and less than 220° C., the weight concentration of the polymer in the dispersion varying between 5 and 50%, with the polymer particles having an average size of less than 10000 nm, as a binder for impregnating strands or strips of natural fibers, in particular flax fibers, with said polymer being incorporated in the core of the fiber bundle forming the strand or strip and thereby binding the fibers together.
US10023703B2 Preparation method of superabsorbent polymer and superabsorbent polymer prepared thereby
Provided are a preparation method of a superabsorbent polymer, and a superabsorbent polymer prepared thereby. The preparation method of the superabsorbent polymer according to the present disclosure enables preparation of the superabsorbent polymer which is excellent in absorption properties such as centrifuge retention capacity and absorbency under pressure, and also has improved permeability. In addition, the preparation method exhibits excellent operability during the preparation (in particular, surface crosslinking of the polymer) and excellent productivity due to low production of coarse particles and fine particles.
US10023695B2 Thermoplastic structure for transporting refrigerant fluid
The invention relates to a thermoplastic structure comprising at least one layer consisting of a composition comprising a copolyamide of formula X/10.T/Y, wherein: X represents either the residues of an aliphatic amino acid comprising between 8 and 18 carbon atoms, or a lactam, or the unit X1.X2 representing the residues resulting from the condensation of an aliphatic diamine comprising between 6 and 18 carbon atoms and a (cyclo)aliphatic diacid comprising between 6 and 18 carbon atoms; 10.T represents the residues resulting from the condensation of a decanediamine and terephthalic acid; and Y represents the residues resulting from the condensation of an aliphatic diamine comprising between 9 and 14 carbon atoms and an aromatic diacid, Y being different from the unit 10.T; the molar proportion of 10.T units in the copolyamide being higher than 0%; the molar proportion of Y units in relation to the group of 10.T and Y units being between 0 and 30%; and the proportion of X units being between 0.4 and 0.8 mole for a mole of semi-aromatic units 10.T and Y.
US10023692B2 Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate
A method for the preparation of a poly(ether ether ketone) (PEEK) includes: preparing the PEEK by aromatic nucleophilic substitution in the presence of: a) particulate sodium carbonate (Na2CO3), wherein said particulate sodium carbonate has a particle size distribution as follows: D90≥45 μm and D90≤250 μm and D99.5≤710 μm, wherein said particle size distribution is measured by mechanical sieving in accordance with ASTM E 359-00 (reapproved 2005), wherein said measurement is based on the mechanical separation of various fractions on a series of superimposed sieves which are superimposed by descending order of opening mesh of 1000 μm, 500 μm, 250 μm, 180 μm, 125 μm, 90 μm, 63 μm, and 45 μm; and b) potassium carbonate (K2CO3) in an amount ranging from 0.001 to about 0.05 mol K/mol Na.
US10023690B2 Hyperbranched phosphoric acid esters
The present invention is directed to a process for preparing hyperbranched phosphoric acid esters as well as a hyper-branched phosphoric acid ester, its use for dispersing solid substances and in the production of water- and/or solvent-based coatings and paints, printing inks and/or plastics such as unsaturated polyesters, PVC or plastisols and a pigment dispersion comprising the at least one hyperbranched phosphoric acid ester or salt thereof and its use as a component in paints or lacquers.
US10023684B2 Universal spot blender for one-component and two-component clearcoatings
The invention relates to binder-free spot blender compositions for one- and two-component clearcoat materials comprising at least one isocyanate compound, to processes for producing them, and to their use in automotive refinish.
US10023680B2 Polyester polyol-containing polyurethane systems having improved hydrolytic stability
An isocyanate reactive composition for making a polyurethane foam includes a tertiary amine urethane catalyst comprising a di(C1-C4)alkyl fatty alkyl amine and a polyester polyol. The use of one or more of fatty alkyl tertiary amine serves to reduce hydrolysis of the polyester polyol in the isocyanate reactive composition.
US10023676B2 Styrene-butadiene block copolymers with an internal butadiene block for tubing applications
Conjugated diene monovinylarene block copolymers containing an internal conjugated diene block and having superior kink resistance properties are disclosed. These copolymers can be used to produce tubing and other end-use articles, and can be a replacement for flexible PVC.
US10023672B2 Polyphenylene oxide prepolymer, method of making the same, resin composition and product made therefrom
Provided is a process of making a polyphenylene oxide prepolymer, comprising a step of reacting a reactive cycloolefin and a vinyl-containing polyphenylene oxide in the presence of a ruthenium catalyst. The reactive cycloolefin may be selected from dicyclopentadiene monomer, dicyclopentadiene oligomer, dicyclopentadiene polymer, norbornene monomer, norbornene oligomer, norbornene polymer, and a combination thereof; the vinyl-containing polyphenylene oxide may be selected from divinylbenzyl polyphenylene oxide resin, vinylbenzyl-modified polyphenylene oxide resin, methacrylic polyphenylene oxide resin, and a combination thereof; the ruthenium catalyst may be a Grubbs catalyst. Also provided are a polyphenylene oxide prepolymer made by the process, a resin composition containing the polyphenylene oxide prepolymer, and a product made from the resin composition.
US10023668B2 Thickened polymer
The invention relates to a polymer which can be obtained by radical emulsion polymerization of at least one acidic vinyl monomer or salt thereof, at least one non-ionic vinyl monomer, in particular preferably a hydrophobic non-ionic vinyl monomer, at least one monomer containing an unsaturated terminal group and a polyoxyalkyene portion, at least one crosslinking monomer, optionally a protective colloid, and is characterized in that the polymerization is controlled such that the gelling effect occurs at least at times, which is achieved by the monomer addition (dosing time) taking place for 40 minutes, particularly preferably for 30 minutes.
US10023667B2 Propylene homopolymer for high-tenacity fibers and nonwovens
Propylene homopolymers having a melt flow index in the range from 3.0 dg/min to 8.0 dg/min can be particularly suited for high-tenacity fibers and yarns and nonwovens. The propylene homopolymers can be produced by a process that can include polymerizing propylene in presence of a Ziegler-Natta polymerization catalyst, an aluminum alkyl, hydrogen and an optional external donor.
US10023666B2 Process for transitioning between low percentage chrome and high percentage chrome catalysts
A method of transitioning from a first catalyst to a second catalyst in a gas phase fluidized bed reactor comprising continuously feeding the first catalyst and a recycle stream comprising olefin monomer to the reactor; wherein the monomer contacts the first catalyst in the fluidized bed and polymerizes; wherein the reactor is operating in condensing mode (withdrawing a gaseous stream comprising unreacted monomer from the reactor, cooling the gaseous stream to condense a portion thereof, and contacting the cooled gaseous stream with fresh monomer to form the recycle stream); and wherein a liquid phase of the recycle stream evaporates within the fluidized bed; discontinuing the first catalyst to the reactor while continuing to feed the recycle stream; maintaining the condensing mode in reactor at >3 wt. % liquid phase in recycle stream while no fresh catalyst is introduced to reactor; and introducing the second catalyst to the reactor operating in condensing mode.
US10023664B2 Polymer
The present application relates to a polymer and a use thereof. The present application may provide a functional polymer which expresses a low solubility to a polar solvent and a non-polar solvent. If applied to the use of cosmetics such as mascara or to medical uses, the polymer in the present application may express a tolerance to diverse solvents such as sebum, sweat, tears and the like, and thus enables makeup to last, etc. Accordingly, the polymer may be applied to diverse uses and used in film forming agents, cosmetic compositions, or cosmetics, or the like.
US10023662B2 Method for reducing odoriferous and/or toxic residual monomer in a latex
A new and efficient toxicity and/or odor reducing method for ethyl acrylate and/or acrylonitrile containing aqueous polymer dispersion is disclosed, which comprises contacting a sufficient amount of an ethyl acrylate/acrylonitrile scavenging compound with a stable aqueous dispersion of a polymer to form a polymeric dispersion that contains less than 1 ppm of ethyl acrylate and less than 1 ppm acrylonitrile; wherein the polymer contains a) polymerized units of acylonitrile and/or ethyl acrylate and b) at least 5 ppm of ethyl acrylate and/or acrylonitrile monomers; and wherein the ethyl acrylate/acrylonitrile scavenging compound are contacted with the dispersion independently from contact of the dispersion with any redox pairs.
US10023658B2 Conjugates of oligomer of hyaluronic acid or of a salt thereof, method of preparation thereof and use thereof
The invention relates to conjugates of hyaluronic acid oligomer according to the general formulae I, II III or IV, or a salt thereof, the method of preparation thereof and use thereof, where the oligomer is bonded to the respective substrate by its ending anomeric center via a bi-functional amino linker by means of an amino or imino bond. This type of conjugates allows releasing oligomers in their native form. The prepared systems exhibited an enhanced biological activity against selected lines of cancer cells.
US10023657B2 Reversible protein multimers, methods for their production and use
Some aspects of this invention are based on the recognition that reversible protein multimers in which monomeric proteins are conjugated to a carrier molecule via chelation complex bonds are stable under physiological conditions and can be dissociated in a controlled manner under physiological, nontoxic conditions. Accordingly, such protein multimers are useful for a variety of in vitro, ex vivo, and in vivo application for research, diagnostics, and therapy. Some aspect of this invention provide reversible MHC protein multimers, and methods of using such multimers in the detection and/or isolation of specific T-cells or T-cell populations. Because reversible MHC multimers can efficiently be dissociated, the time of MHC binding to T-cell receptors, and, thus, T-cell receptor-mediated T-cell activation can be minimized. The use of reversible MHC multimers as provided herein, accordingly, allows for the detection and isolation of bona fide antigen-specific CD8+ T cells without inducing activation dependent cell death, including rare, therapeutically valuable T-cells expressing T-cell receptors binding tumor antigens with high affinity. Methods for the production and use of reversible multimers are also provided.
US10023650B2 Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
The present invention provides for recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens, along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to the nucleic acids, and uses for these antibodies, nucleic acids and amino acids.
US10023649B2 Method of treating cancer with a combination of an anti-CCR4 antibody and a 4-1BB agonist
The present disclosure describes combination therapies comprising an antibody which specifically binds to human CCR4 and a selective 4-1BB agonist, and the use of the combination therapies for the treatment of cancer.
US10023645B1 Anti-CD40 antibodies
The present disclosure provides novel anti-CD40 antibodies, compositions including the new antibodies, nucleic acids encoding the antibodies, and methods of making and using the same.
US10023643B2 Antibodies against human CSF-1R and uses thereof
The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
US10023640B2 Human anti-VEGFR-2/KDR antibodies
The invention relates to antibodies that bind to VEGFR-2. The antibodies are used for treating neoplastic diseases, hyperproliferative disorders, and angiogenic disorders and can be used alone or in combination with other agents.
US10023637B2 Combination immunotherapy for the treatment of cancer
Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-1, etc.) are demonstrated herein to be useful for the treatment of tumors.
US10023636B2 Caninized murine antibodies to human PD-1
The present invention provides caninized murine anti-human PD-1 antibodies that have specific sequences and a high binding affinity for canine PD-1. The invention also relates to use of these antibodies in the treatment of dogs.
US10023634B2 Antibodies against TIM3 and uses thereof
Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
US10023633B2 Method for generation of immunoglobulin sequences
The present invention relates to a method for generating immunoglobulin sequences against cell-associated antigens, more particularly, antigens that are membrane-anchored. The invention also provides immunoglobulin sequences obtainable by the method of the invention. Specifically, the present invention relates to the generation of immunoglobulin sequences by use of DNA vaccination. More specifically, the present invention relates to generation of immunoglobulin sequences in camelids, preferably directed against cell-associated antigens, in particular antigens with multiple transmembrane spanning domains, including GPCRs and ion channels, by DNA vaccination. Furthermore, the present invention relates to said immunoglobulin sequences against cell-associated antigens, more particularly, antigens that are membrane-anchored, such as e.g. GPCRs and ion channels, more preferably ion channels.
US10023626B2 Polynucleotides encoding immune modulating polypeptides
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules encoding at least one polypeptide of interest to modulate the immune response.
US10023625B2 Engineered high-affinity human T cell receptors
T cell receptors (TCRs) that have higher affinity for the Survivin antigen are provided. The high affinity TCRs were engineered through the generation of mutational libraries of TCRs in a single-chain format, followed by selection for improved stability and affinity on the surface of yeast (i.e. directed evolution). In embodiments, the engineered TCRs can be used in soluble form for targeted delivery in vivo, or as genes introduced into T cells in an adoptive T cell setting.
US10023623B2 Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared to the same active protein not linked to mucin-domain polypeptide, as well as methods for making and using the fusion proteins of the invention.
US10023622B2 Method of immunization for reducing toxic damaged caused by oligomeric form of the amyloid-beta protein with stable amyloid beta monomers and oligomers
The invention provides monomeric and oligomeric amyloid beta peptide isomers that are resistant towards fibrillogenesis and their use as screening reagents or antigens in methods and pharmaceutical preparations for the treatment of Alzheimer's disease and other conditions related to protein misfolding. The invention further provides transgenic animals expressing modified amyloid precursor proteins or amyloid beta peptides.
US10023615B2 Efficient transport into white blood cells
The present invention relates to the use of specific transporter cargo conjugate molecules for the transport of a substance of interest (cargo molecule) into white blood cells. Said transporter cargo conjugate molecules may be used for the treatment, prophylaxis, attenuation and/or amelioration of a disease and/or disorder involving white blood cells. The present invention also relates to manufacture of said transporter cargo conjugate molecules, to a method of transporting a substance of interest (cargo) into a white blood cell and to a white blood cell comprising said transporter cargo conjugate molecules or fragments thereof.
US10023613B2 Peptidomimetic macrocycles as modulators of MCL-1
The disclosed peptidomimetic macrocycles modulate the activity of MCL-1. Myeloid cell leukemia 1 (MCL-1) is a protein that inhibits cell death. Peptidomimetic macrocycles, pharmaceutical compositions, and methods disclosed herein can be used for the treatment of disease in which MCL-1 is over-expressed, such as cancer. In particular, MCL-1-modulating peptidomimetic macrocycles disclosed herein can be applied in the setting of resistance to BCL-2 family inhibitors, which is often engendered by MCL-1 over-expression or hyper-activation.
US10023611B2 Process for the preparation of bortezomib mannitol ester
A novel and improved process for preparation of bortezomib mannitol ester is derived, which process avoids excessive use of solvents, involves convenient, industrially feasible and economical techniques, and provides improvements in purity over processes known in the art.
US10023606B2 19-nor neuroactive steroids and methods of use thereof
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.
US10023604B2 Non-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
US10023601B2 Hydrolysis resistant sialic acid derivatives and methods for their use
This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, improved biological stability or an improved pharmacokinetic property.
US10023599B2 Design, synthesis, and biological activity of platinum-benz[c]acridine hybrid agents and methods associated therewith
The present invention relates to the compounds of formula I, pharmaceutically acceptable salts, and solvates thereof: wherein the various substituents are as defined herein. The compounds, solvates and salts thereof of Formula I are effective as anti-cancer compounds.
US10023593B2 ALK kinase inhibitor, and preparation method and uses thereof
An ALK kinase inhibitor compound as represented by Formula I, pharmaceutical composition containing the compound, and preparation method and use thereof in the preparation of drugs serving as an ALK inhibitor for treating cancer.
US10023592B2 Bromodomain inhibitors
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
US10023591B2 Heterocyclic derivatives and use thereof
A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein.
US10023590B2 Substituted pyridine compounds having herbicidal activity
The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.
US10023589B2 Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators
Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.
US10023586B2 Enhanced regio-selectivity in glycol acylation
A method for acid-catalyzed acylation of an isohexide is described. The method involves a reaction of an isohexide and an excess of carboxylic acid in the presence of a Lewis acid or a Brnsted acid catalyst. One or more Lewis acid or Brnsted acid can facilitate conversion of isohexides to their corresponding mono and diesters with a pronounced greater regio-selectivity of exo-OH over endo-OH of the isohexide in the product. Particular catalytic acid species include zirconium chloride (ZrCl4) and phosphonic acid (H3PO3), which manifest a ratio of exo:endo regioselectivity of about 5.0≠3:1 and about 4.00.3:1, respectively.
US10023582B2 6-aryl amino pyridone formamide compound crystal and preparation method therefor
The present invention provides a crystal of 6-arylamino pyridone carboxamide compound and a preparation method thereof. The crystal is obtained by dissolving 6-(2-chloro-4-iodophenylamino)-N-(2-hydroxylethyoxyl)-5-methyl-4-oxo-4,5-dihydrofuro[3,2-c]pyridin-7-carboxamide in an aprotic polar solvent and adding a second solvent thereto. The crystallization method has the advantage of simple and convenient operations, and is beneficial to an industrial production. The resulting crystal has the advantage a high purity and good stability, and is benefit to the manufacture and storage of a medicament containing the same.
US10023578B2 Crystals of dispiropyrrolidine derivatives
Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of (3′R,4′S,5′R)—N-[(3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl]-6″-chloro-4′-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2″-oxo-1″,2″-dihydrodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indole]-5′-carboxamide or a salt thereof which inhibits Mdm2 and has anti-tumor activity. The present invention also provides a medicament comprising the same.
US10023573B2 Beta-lactamase inhibitor and process for preparing the same
A process for preparing a diazabicyclooctane compound represented by the following formula (I): wherein A represents RcO—; B represents NH or NC1-6 alkyl; C represents a benzyl group; Rc represents a C1-6 alkyl group; A is substituted with one substituent Fn1, wherein Fn1 represents an azetidine group; the process including: (a) silylating the compound represented by the following formula (IV-c): wherein in the formula (IV-c), OBn represents benzyloxy, and (b) carrying out an intramolecular urea formation reaction.
US10023568B2 Naphthyridine derivatives useful as αvβ6 integrin antagonists
A compound of formula (I) or a salt thereof wherein R1 represents a hydrogen atom, a methyl group or a ethyl group R2 represents a hydrogen atom or a fluorine atom R3 represents a hydrogen atom, a methyl group or an ethyl group.
US10023566B2 Dasatinib salts
The invention relates to normal or acidic salts of dasatinib and the hydrate and solvate forms thereof. More specifically the invention concerns: dasatinib cyclamic acid salt, dasatinib cyclamic acid (1:1) salt Form I, dasatinib cyclamic acid (1:1) salt Form II, dasatinib hydrogen bromide (1:2) salt, dasatinib methane sulfonic acid (1:2) salt, dasatinib p-toluenesulfonic acid (1:1) dihydrate salt, anhydrous dasatinib p-toluenesulfonic acid (1:1) salt Form I, anhydrous dasatinib p-toluenesulfonic acid (1:1) salt Form II, dasatinib p-toluenesulfonic acid (1:1) salt methanol solvate. Moreover the invention relates process for preparing dasatinib salts, pharmaceutical compositions comprising thereof and the use of dasatinib salts the treatment of cancer.
US10023564B2 G protein-coupled receptor kinase 2 inhibitors and methods for use of the same
Disclosed herein are novel GRK2 inhibitors and methods for their use in treating or preventing heart disease, such as cardiac failure, cardiac hypertrophy, and hypertension. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salt thereof: wherein the substituents are as described.
US10023561B2 Fumagillol heterocyclic compounds and methods of making and using same
Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
US10023560B2 Crystalline salt form of (S)-(2-(6 chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone as orexin receptor antagonist
The invention relates to a crystalline form of (S)-(2-(6-chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone hydrochloride, processes for the preparation thereof, pharmaceutical compositions containing said crystalline form, and its use as medicament, especially as orexin receptor antagonist.
US10023557B2 Therapeutic inhibitory compounds
Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting plasma kallikrein. Furthermore, the subject compounds and compositions are useful for the treatment of diseases wherein the inhibition of plasma kallikrein inhibition has been implicated, such as angioedema and the like.
US10023555B2 NSAIDs derivatives and uses thereof
The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof.
US10023554B2 Halogen-substituted heterocyclic compound salt
The invention provides a novel α-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a medicament.The salt is represented by the general formula (I): (wherein R is a hydrogen atom or a methoxy group; X is a halogen atom; A is selected from the group consisting of: M is an alkali metal or an alkaline earth metal; and n is 1 when M is an alkali metal and is 2 when M is an alkaline earth metal).
US10023546B2 Acesulfame potassium compositions and processes for producing same
Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.
US10023542B2 Ibrutinib intermediate compounds, preparation methods and uses thereof
The present invention relates to the technical field of ibrutinib, particularly to the technical field of ibrutinib intermediate compounds and preparation methods thereof. The intermediate compounds are represented by formula A, wherein, the dotted line represents a double bond or a single bond between carbon and oxygen.
US10023539B2 Aryl-cyanoguanidine compounds
The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (I) wherein R1, R2, R3, R4, R5, X and r have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyper-proliferative disorders, in particular for cancer, respectively tumor disorders. The present invention furthermore relates to the use of SMYD2 inhibitors for benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, neurodegenerative disorders, inflammatory disorders, atherosclerotic disorders and the control of male fertility.
US10023537B2 Heterocyclic compounds for the treatment of neurological and psychological disorders
Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
US10023528B2 Branched 3-phenylpropionic acid derivatives and their use
The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
US10023525B2 Preparation of 18F-fluciclovine
The present invention provides a method for the production of [18F]-FACBC which has advantages over know such methods. Also provided by the present invention is a system to carry out the method of the invention and a cassette suitable for carrying out the method of the invention on an automated radiosynthesis apparatus.
US10023523B2 Systems and methods for making bioproducts
Processes for continuous preparation of bioproducts are described herein. The processes include contacting fatty acid glycerides with alcohols in the presence of an acidic heterogeneous catalyst and separating the fatty acid alkyl esters from the reaction products.
US10023522B2 Hydroxyalkyl acrylate and method for producing same
The hydroxyalkyl acrylate according to the present invention is characterized in that a content amount of an ester generated from acrylic acid dimer and an alkylene oxide is not more than 0.10 mass %. The method for producing a hydroxyalkyl acrylate according to the present invention is characterized in comprising the step of reacting acrylic acid with an alkylene oxide in the presence of a catalyst, wherein a content amount of acrylic acid dimer in the raw material acrylic acid is not more than 3.00 mass %.
US10023521B2 Process and intermediates for preparing poly(anhydride-esters)
Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a solvent, to provide a diacid of formula (II), wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
US10023519B2 Cyclobutane containing carboxylic acid GPR120 modulators
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
US10023515B2 Method for preparing cyclohexanone by hydrogenating phenol
A method of preparing cyclohexanone by hydrogenating phenol is provided. The method includes a step of introducing an additional flammable gas to dilute hydrogen gas concentration, so as to increase the throughput and decrease energy consumption. Further, the discharged residual gases from the hydrogenation of phenol have a calorific value. Also provided is a system for generating cyclohexanone by hydrogenating phenol.
US10023514B2 Odorants of the violet type
The present invention relates to the use as perfuming ingredient, in particular to confer odor notes of the violet, violet leaves type, of a compound of formula (I), wherein n represents 1 or 2, A represents CH2 or CO; and R represents a C1-4 alkyl or alkenyl group or a C3 cycloalkyl group, or when A is a CH2 group R may also represent a C1-3 acyl group. Moreover, following what is mentioned herein, the present invention comprises the invention's compound as part of a perfuming composition or of a perfuming consumer product.
US10023513B1 Telomerization methods of using ethylene and/or propylene to make telomers of limited molecular weight
The principles of the present invention are useful in telomerization reactions in which ethylene and/or propylene taxogen is used in free radical reactions to make telomers of limited molecular weight, e.g., those in which a major portion of the telomer products are telomers incorporating 1 to 12 moles of ethylene and/or propylene per mole of telogen (i.e., a major portion of the telomer products incorporate telomers for which n is 1 to 12). The present invention is based at least in part upon the discovery that using a very large stoichiometric excess of C1 to C12 telogen(s) (i.e., telogens incorporating 1 to 12 carbon atoms per molecule) in combination with using very low concentrations of initiator provides telomerization reactions that are selective for producing lower molecular weight telomers. In many embodiments, the present invention provides a product mixture of telomers in which a major portion of the product mixture contains telomers that incorporate 1 to 12, preferably 1 to 7, more preferably 1 to 5, even more preferably 1 to 3 moles of ethylene and/or propylene per mole of telogen.
US10023509B2 Processes and apparatuses for production of aromatic products
Processes and apparatuses for producing a C8 aromatic isomer product are provided. The apparatus comprises an isomerization unit to provide an isomerized stream. An isomerate stripper column is in communication with the isomerization unit to provide an isomerate stripper overhead stream comprising C6− hydrocarbons in an isomerate overhead line and an isomerate stripper bottoms stream in an isomerate bottoms line. A dividing wall naphthene splitter column is in communication with the isomerate bottoms line to provide an overhead naphthene splitter stream comprising the C8 naphthenes and C7 aromatic hydrocarbons in a naphthene splitter overhead line and a naphthene splitter sidedraw stream comprising C8 aromatic isomers in a naphthene splitter sidedraw line. An extractive distillation column is in communication with the naphthene splitter overhead line to provide a recycle feedstream comprising the C8 naphthenes in a recycle line and an extract stream comprising the C7 aromatic hydrocarbons in an extract line.
US10023508B2 Viscosity modifiers for decreasing the viscosity of ionic liquids
A process utilizing an ionic liquid is described. The process includes contacting a hydrocarbon feed with an ionic liquid component, the ionic liquid component comprising a mixture of a first ionic liquid and a viscosity modifier, wherein a viscosity of the ionic liquid component is at least about 10% less than a viscosity of the first ionic liquid.
US10023505B2 Method of producing solid propellant element
A method of producing a propellant material element, such as an electrically-operated propellant material, includes extruding a propellant material through a heated nozzle. The nozzle may be heated to a temperature that is above the boiling point of a solvent that is part of the propellant material, yet is below a decomposition temperature of the propellant material. This allows some of the solvent to be driven off during the extruding process, while still preventing initiation of an energy-creating reaction within the material. The heating of the material in the extruding process, and especially the heating of the nozzle that the material is extruded through, may be controlled to remove an amount of solvent that results in the extruded material having desirable properties.
US10023495B2 Glass containers with improved strength and improved damage tolerance
The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. A compressively stressed layer may extend from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa. A lubricous coating may be positioned around at least a portion of the outer surface of the body. The outer surface of the body with the lubricous coating may have a coefficient of friction less than or equal to 0.7.
US10023494B2 Coated article having low-E coating with absorber layer(s)
A coated article is provided, having a coating supported by a glass substrate where the coating includes at least one color and/or reflectivity-adjusting absorber layer. The absorber layer(s) allows color tuning, and reduces the glass side reflection of the coated article and/or allows sheet resistance of the coating to be reduced without degrading glass side reflection. In certain example embodiments the absorber layer is provided between first and second dielectric layers which may be of substantially the same material and/or composition. In certain example embodiments, the coated article is capable of achieving desirable transmission, together with desired color, low reflectivity, and low selectivity, when having only one infrared (IR) reflecting layer of silver and/or gold. Coated articles according to certain example embodiments of this invention may be used in the context of insulating glass (IG) window units, monolithic windows, or the like.
US10023493B2 Temperable enamelled glass
A colored lacquered substrate made of glass or glass-ceramic includes a mineral coating based on alkaline silicate, which achieves the required performance in terms of color and of change in color during tempering, and in terms of adhesion and of mechanical strength at low temperatures without requiring a high-temperature baking step.
US10023492B2 Bismuth borate glass encapsulant for LED phosphors
Embodiments are directed to glass frits containing phosphors that can be used in LED lighting devices and for methods associated therewith for making the phosphor containing glass frit and their use in glass articles, for example, LED devices.
US10023488B2 Synthetic amorphous silica powder and method for producing same
The synthetic amorphous silica powder of the present invention is characterized in that it comprises a synthetic amorphous silica powder obtained by applying a spheroidizing treatment to a silica powder, and by subsequently cleaning and drying it so that the synthetic amorphous silica powder has an average particle diameter D50 of 10 to 2,000 μm; wherein the synthetic amorphous silica powder has: a quotient of 1.00 to 1.35 obtained by dividing a BET specific surface area of the powder by a theoretical specific surface area calculated from the average particle diameter D50; a real density of 2.10 to 2.20 g/cm3; an intra-particulate porosity of 0 to 0.05; a circularity of 0.75 to 1.00; and an unmolten ratio of 0.00 to 0.25. This synthetic amorphous silica powder is less in amount of gas components adsorbed to surfaces of particles of the powder and in amount of gas components within the particles, so that a synthetic silica glass product manufactured by using the powder is remarkably decreased in amount of generation or degree of expansion of gas bubbles even upon usage of the product in a high temperature and reduced pressure environment.
US10023482B2 Method and system for injecting RF signal into a fluid-containing system
A method and system for injecting a pulsed radio frequency signal into a fluid-containing system in order to create and propagate an electromagnetic field throughout the fluid-containing system. The electromagnetic field may be used to prevent the formation and build-up of scale in the fluid-containing system and/or to prevent the proliferation of bacteria within the fluid-containing system. The method and system may also be used to inject a pulsed radio frequency signal at a number of points in a fluid-containing system, or to inject a pulsed radio frequency signal to a number of independent fluid-containing systems.
US10023477B2 Treatment solution supply method, treatment solution supply apparatus, and non-transitory computer-readable recording medium
A treatment solution supply method of supplying a treatment solution to a substrate, the method includes the steps of: applying a DC voltage to the treatment solution; detecting a potential difference between two points in the treatment solution in a state where the DC voltage is applied to the treatment solution; and increasing the DC voltage when the detected potential difference is less than a predetermined reference value.
US10023472B2 Aluminum oxide production method
The invention pertains to methods of producing aluminum trioxide in the form of powders or agglomerations with particles having a porous honeycomb structure, which can be used as catalyst substrates, adsorbents and filters for the chemical, food, and pharmaceutical industry. The method of production of aluminum oxide in the form of powders or agglomerations with particles having a porous honeycomb structure involves the treatment of the aluminum salt with a solution of an alkaline reagent, washing of the sediment and thermal treatment thereof. The technical result of the invention is the production of aluminum oxide in the form of separate particles with given structure and properties, specifically, with particle porosity of 60-80% and a porous structure represented by extensive parallel channels with near hexagonal packing, with dimension of the channels at the diameter of 0.3 to 1.0 micron and length up to 50 microns. For this, the aluminum salt used is crystals of aluminum chloride hexahydrate, which are treated with an excess aqueous solution of ammonia at temperature of 20-80° C. to form boehmite, and the heat treatment is done at 450-650° C. until aluminum oxide is formed.
US10023471B2 Precipitated silica and paper industry/other applications thereof
Precipitated silica specifically useful in the paper industry and in particular in paper-coating applications for inject printing, is characterized by an uptake of DOP oil lower than 260 ml/100 g, a pore volume (Vd25) of greater than 0.8 ml/g formed by pores having a diameter of less than 25 nm, a CTAB specific surface area of greater than 280 m2/g.
US10023470B2 Process for preparing octachlorotrisilane and higher polychlorosilanes with utilization of hexachlorodisilane
A controlled preparation of octachlorotrisilane and higher polychlorosilane such as DCTS and DCPS from monomeric chlorosilane, proceeds by exposing the chlorosilane to a nonthermal plasma and recycling chlorosilane that has not been converted to octachlorotrisilane into the plasma.
US10023464B2 Production of phosphate compounds from materials containing phosphorus and at least one of iron and aluminium
A method for concentration of phosphate compounds comprises dissolving (205) of sludge ash in hydrochloric acid. Insoluble residues are separated (210), thereby forming a first leach solution. A mole ratio of phosphorus to a sum of ferric iron and aluminum in the first leach solution is controlled (215) to be larger than 1. A base is added (220) to the first leach solution in an amount causing precipitation of phosphate compounds. The precipitated phosphate compounds are removed (225) from the first leach solution. Sulphuric acid is added (240) to the first leach solution, causing precipitation of sulphate compounds. The precipitated sulphate compounds are separated (245) from the first leach solution. At least a part of the leach solution is recycled (248) as the hydrochloric acid used for the dissolving of sludge ash. Further methods for processing the precipitated phosphate compounds are presented as well as arrangements for performing the methods.
US10023459B2 MEMS and method for forming the same
A method and apparatus are provided to prevent or reduce stiction of a MEMS device. The MEMS device may include a protrusion extending from a surface of the MEMS device. During manufacture, the protrusion may be connected across an opening in the MEMS device to a sidewall of the substrate. Before manufacture of the MEMS device is completed, at least a portion of the protrusion connecting the MEMS device to the substrate may be removed. During operation, the protrusion may provide stiction prevention or reduction for the surface from which the first protrusion may extend. A plurality of protrusions may be formed along a plurality of surfaces for the MEMS device to prevent or reduce stiction along the corresponding surfaces. Protrusions may also be formed on devices surrounding or encapsulating the MEMS device to prevent or reduce stiction of the MEMS device to the surrounding or encapsulating devices.
US10023457B2 Conversion fitting
A conversion fitting configured to matingly engage with a conduit coupler having conduit coupler thread configured as American Standard hose coupling thread or American Standard hose coupling thread for garden hose applications and a container aperture element having container aperture element internal thread configured as bunghole thread to facilitate the transfer of fluid therebetween.
US10023454B2 Multichannel liquid delivery system
A system includes rigid reservoirs, each divided by a flexible diaphragm into a hydraulic chamber and a delivery chamber. The hydraulic chamber is connected to a hydraulic liquid conduit via a valve and the delivery chamber is connected to a delivery conduit. A hydraulic actuator is operable to apply pressure to the hydraulic liquid so as to force the hydraulic liquid into a hydraulic chamber whose valve is open, pushing the diaphragm distally to force the delivery liquid from the delivery chamber into the connected delivery conduit. The actuator is also operable to apply suction to the hydraulic liquid in the hydraulic liquid conduit so as to draw hydraulic liquid from the hydraulic chamber, proximally pulling the flexible diaphragm to draw the delivery liquid from the delivery conduit into the delivery chamber.
US10023449B1 Skid loader attachment
An apparatus generally directed to a skid loader attachment, which includes at least, but is not limited to, a universal mounting structure, a pair of slide shaft support flanges secured to and protruding from a proximal end of the universal mounting structure, a slide shaft attached to and disposed between the pair of slide shaft support flanges, the slide shaft spaced apart from and in non-contact adjacency with the universal mounting structure, and a tine adjustment structure secured to and protruding from a distal end of the universal mounting structure.
US10023448B2 Lift truck with mast
A lift truck includes an operator compartment and a pair of forks extending away from said operator compartment in a forward direction. A pair of mast columns are interposed between the operator compartment and the forks. Components mounted on at least one of the mast columns are arranged to fall within a viewing shadow so as not to obstruct the operator's field of view.
US10023443B2 Tower crane and method of mounting a wind turbine rotor blade
The invention relates to a tower crane comprising a tower of at least one tower element, in particular a lattice piece, and a structural guying device having at least one guying rod for the horizontal anchorage of the tower at a structure. In accordance with the invention, the tower has a vertically adjustable guide frame, wherein at least one positioning rope is adjustably fastened to the guide frame. The invention furthermore relates to a method of mounting a wind turbine rotor blade.
US10023441B2 Gripping device for handling reinforcement cages for tower segments of a wind turbine
A gripping device for handling reinforcement cages for tower segments of a wind turbine, comprising a gripper arm holding fixture and multiple gripper arms arranged radially on the gripper arm holding fixture. In particular, it is proposed that there is a coupling mechanism that can be connected with the reinforcement cage on each gripper arm, the length of the gripper arms can be telescopically motor-adjusted, the gripping device can be coupled with a lifting device that can be moved horizontally and vertically, and is adapted to move a reinforcement cage from apparatus for manufacturing reinforcement cages and/or to put a reinforcement cage down in a casing for creating a tower segment.
US10023440B2 System and method for measuring safety clearance between the steps and skirt panels of an escalator and positioning hidden dangers
The present disclosure discloses a system and method for measuring safety clearance between the steps and skirt panels of an escalator and positioning hidden dangers and, which improves the working efficiency of the detecting personnel and reduces labor intensity; the system and method of the present disclosure has high accuracy, and eliminates the detection error caused by manual observation and the sense of responsibility, thus helping the detecting personnel to comprehensively detect the hidden dangers to minimize the escalator safety accidents caused by such hidden dangers; and its accurate hidden danger positioning function can help the maintenance personnel to carry out maintenance and adjustment faster. Therefore, the present disclosure is of great significance to the safe operation of the escalator and the personal safety of the passengers, and plays a positive role in promoting the development of the whole quality supervision.
US10023438B2 Conveying system for open-cast mining
A conveying installation that is positionable over an oblique slope of an opencast mine pit may be used to convey raw materials from a lower height level on an extraction level of the opencast mine to an upper height level at a ground level adjacent to the opencast mine pit. At least one conveying container can be loaded with raw materials at the lower height level and unloaded at the upper height level. At least one bearing cable for load-bearing and control and one traction cable for moving the conveying container may be provided. At least at the upper height level, a support element may be disposed, to which the bearing cable is attached and on which the traction cable is guided.
US10023436B2 Drive with multiple looping for an elevator installation
A drive unit for an elevator installation having a first traveling body and a second traveling body, which traveling bodies are supported by a support device, drives the support device and thus the two traveling bodies. The two traveling bodies each have at least one first support roller by which the support device supports the traveling bodies, at least partially. The drive unit includes at least one first and one second roller arranged on a common axis of rotation of the drive unit, wherein at least one of the first or second rollers is a drive unit roller for driving the support device. On the way from the first traveling body to the second traveling body, the support device is guided over the first drive unit roller and over the second drive unit roller. The guidance is hereby such that the circumferential speeds of the two drive unit rollers vary.
US10023435B2 Hoisting apparatus with enclosure and lifting platform
The hoisting apparatus includes a climbing rail, which is adapted to be suspended on and translated vertically along a construction at a distance from the ground. There is an enclosure supported by the climbing rail. There is also a lifting platform that is housed within the enclosure and is vertically movable relative to the enclosure.
US10023429B2 Brake for elevator systems
A brake unit for a safety brake of an elevator system has a rolling element on a rolling disk, which rolling element rolls on a stationary rolling track of a braking and guiding rail at least in some sections in the event of an activation of the safety brake. A brake lining of the brake unit interacts with a stationary braking track on the rail as a result of the rolling of the rolling element on the rolling track. At least one marking element on the rolling element produces a start marking and an end marking on the rolling track and/or the braking track when the rolling element rolls on the rolling track. Then the braking distance of the associated elevator car can be determined from the distance between the start marking and the end marking.
US10023427B2 Touchless gesture recognition for elevator service
A method for provisioning elevator service includes sensing, by a gesture interface including a sensor, a region in proximity to the gesture interface to obtain data; determining, by the gesture interface, that a first pattern in the data corresponds to a first gesture; and initiating a request for elevator service in response to determining that the first pattern corresponds to the first gesture.
US10023426B2 Coil making apparatus and method
An apparatus (1) and a method for coiling a cable (2) or a wire into a coil (3) having a plurality of turns (3a) and two free ends (4, 5) formed by a leading end (4) and a trailing end (5) of said cable are disclosed. The apparatus comprises a rotatable coil former (6) around which a cable is coiled; means (9) to measure the length of the coiled cable (2) or wire; first holding means (10) positioned on said coil former (6) for holding the leading end (4) of the cable, second holding means (12), separate from said coil former (6) for receiving and holding the leading end (4) of the cable (2), which are movable. Cutting means (14) for cutting the coiled cable to provide a trailing end (5) of the cable are also provided. The apparatus further comprises means (7) to adjust the diameter (D1, D2) of the coil former (6) and control means (18) to set said adjusting means (7) of the diameter of the coil former (6), to provide the required length of the cable and the required length of the said free ends (4, 5) of the coiled cable.
US10023423B2 Sheet processing apparatus, image forming system, and method of additionally folding sheet bundle
A sheet processing apparatus includes a pressing unit including a first pressing member and a second pressing member. The pressing unit is configured to sandwich and press a fold part of a folded sheet bundle between the first pressing member and the second pressing member. The sheet processing apparatus also includes a moving unit configured to move a position pressed by the pressing unit in a direction of a fold of the sheet bundle. A position pressed by the first pressing member on the sheet bundle and another position pressed by the second pressing member on the sheet bundle are shifted with respect to each other in the direction of the fold of the sheet bundle.
US10023422B2 Sheet processing device and image forming device provided with the sheet processing device
A sheet processing device performs saddle stitching binding a bundle of stacked paper sheets, and includes a stacker section temporarily stacking conveyed paper sheets substantially vertically; a stopper regulating the paper sheets stacked in the stacker section; a first binding section provided in the stacker and saddle-stitching a paper sheet bundle regulated by the stopper at a binding position around a center of the paper sheet bundle in a sheet conveying direction; a folding section folding in half the paper sheet bundle regulated by the stopper; and a conveying section conveying the paper sheet bundle that has been folded in half by the folding section with a back side of the folded paper sheet bundle as a leading end in the conveying direction. The conveying section includes a second binding section binding the folded paper sheet bundle at the back side thereof.
US10023420B2 Paper-sheet counting machine
A paper-sheet counting machine (10) includes: a recognition and counting unit (24) configured to count paper sheets; a stacking unit (26) configured to stack therein the paper sheets that have been counted by the recognition and counting unit (24), an opening being provided in a front face of the stacking unit (26); a rotary guide unit (28) provided to the stacking unit (26) and configured to allow the paper sheets that have been counted by the recognition and counting unit (24) to be stacked in the stacking unit (26); a shutter (40) configured to close the opening provided in the front face of the stacking unit (26); a shutter drive unit (50) configured to drive the shutter (40) to open and close the opening provided in the front face of the stacking unit (26); and a control unit (70) configured to control the shutter drive unit (50).
US10023418B2 Reception apparatus
A reception apparatus that receives an article discharged from a processing apparatus includes a first rod, second rod and a reception sheet. The first rod extends in a direction crossing a direction of the discharge below a discharge port of the processing apparatus in a gravity direction. The second rod extends in the direction crossing the direction of the discharge at a position farther away from the discharge port than the first rod. The reception sheet has flexibility, is supported by the first rod and the second rod, and receives the article discharged between the first rod and the second rod. The first rod is capable of being disposed at a first position and a second position which are different from each other in the gravity direction.
US10023416B2 Inter-roller conveyance control device
An inter-roller conveyance control device conveying an object to be conveyed between a speed shaft roller driven by a speed shaft motor and a tension shaft roller driven by a tension shaft motor while providing tension to the object includes a gain table that stores a plurality of pairs of a conveyance condition variable changing while the object to be conveyed is conveyed and affecting an appropriate value of a control parameter and a control parameter candidate value that is an appropriate control parameter where, when the conveyance condition variable is changed, the device performs calculation on the basis of the conveyance condition variable and a gain calculation result and writes, into the gain table, the control parameter candidate value and the conveyance condition variable in association with each other when the calculation is completed.
US10023411B2 Sheet conveyance apparatus
A sheet conveyance apparatus includes a conveyance roller, a first rotary member forming a first nip portion conveying a sheet in a first conveyance direction, a rotation axis of the first rotary member being inclined with respect to a rotation axis of the conveyance roller such that a center of one end of the first rotary member is positioned at a different position in the first conveyance direction with respect to a center of the other end, and a second rotary member forming a second nip portion conveying a sheet in a second conveyance direction, a rotation axis of the second rotary member being inclined with respect to the rotation axis of the conveyance roller such that a center of one end of the second rotary member is positioned at a different position in the second conveyance direction with respect to a center of the other end.
US10023404B2 Workpiece handling systems and related devices and methods
In some aspects, an unloading device for a pipe processing system includes a depositing carriage having a depositing surface for depositing a pipe during and/or after a pipe processing operation, the depositing carriage being configured to move in a longitudinal direction of the pipe, and a supporting carriage having a supporting member for the pipe, the supporting member having a wall for radially supporting the pipe, and the supporting carriage being configured to move in a longitudinal direction of the pipe, where the depositing surface of the depositing carriage and/or the supporting member of the supporting carriage is configured to move in at least one other direction in addition to the longitudinal direction of the pipe so that the depositing carriage and the supporting carriage can be at least partially moved past each other along the longitudinal direction of the pipe.
US10023402B2 System and method for carrier identification in a pneumatic tube system
A system and method provides for the identification and monitoring of carriers within a pneumatic carrier system. Each carrier which is to be employed within the system includes an identification device such as a radio frequency identification (RFID) chip which has stored thereon identification information for the carrier. Positioned throughout the system are communications devices such as antennas and readers which are employed to read and/or write identification information on the chip. When a carrier is put in the system, a destination location can be associated with the particular carrier ID. This associated information is then employed to, among many things, monitor and confirm identity of the carrier as it moves to its destination.
US10023396B2 Device for separating piece goods to be stored in an automated storage facility
A device for separating piece goods to be stored in an automated storage facility is provided. The device includes a conveyor for conveying piece goods from a stock to a support surface of a collecting device, a controller for controlling the conveyor, a sensor, to detect the striking of the support surface by piece goods. The detector has an imager, which produces at least one recording of the underside of the support. A handling device is configured to remove a piece good from the support surface for further transport into the storage facility is coupled to the controller, which is further configured to control the handler according to the information.
US10023393B2 Robotic tossing of items in inventory system
Robotic arms or manipulators can be used to toss inventory items within an inventory system. Tossing strategies for the robotic arms may include information about how a grasped item is to be moved and released by a robotic arm to achieve a trajectory for moving the item to a receiving location. A tossing strategy may also use a trajectory that avoids time and/or space reserved for a trajectory of another tossed item. The receiving location can include surfaces and/or other features that can be manipulated for receiving the item based on one or more characteristics of the tossed item and/or a trajectory of the tossed item.
US10023392B2 Belt driven linear actuator
A belt driven linear actuator includes: a base, a linearly movable unit, a belt driven unit, a first cover, a second cover, a drive source, and a slide block. With the first and second covers removably disposed on the base, the first and second covers can be located at different positions to define different gaps in different directions, so as to allow the slide block to be assembled in different directions, and reduce the restriction on the assembling direction of the drive source. Besides, the width of the base is equal to the height of the base, and the height of the cover portion is equal to the height and the width of the base, which allows the base to be assembled in the same position while in different directions.
US10023388B2 Positive-drive spiral conveyor
A spiral conveyor for positively driving a conveyor belt along a helical path. The spiral conveyor includes a rotating cylindrical tower with parallel drive members extending from the bottom to the top of the tower on its periphery. Each drive member includes an outwardly protruding ridge that varies in height from the bottom to the top of the tower. The variations in height facilitate the belt's entry onto and exit from the tower and robust, positive driving engagement with the inside edge of the belt along the majority of its path along the tower.
US10023381B2 Textile silica reduction system
Apparatus for reducing airborne proppant adjacent a fracking material handling system. In some embodiments, a proppant reduction cover is mounted over a first aperture of a proppant storage chamber and has a permeable filter material adapted to facilitate a first flow of displaced air therethrough as proppant is loaded into the chamber. A vent sock is mounted over a second aperture of the chamber and has a permeable filter material facilitate a second flow of displaced air therethrough during the loading of the proppant. A vacuum adapter is mounted over a third aperture of the chamber to apply a negative pressure to an interior of the proppant storage chamber during said loading of the proppant.
US10023380B2 Flexible intermediate bulk container with induction control
A method, apparatus and system is provided for both (1) decreasing electrostatic discharges to reduce the potential for incendiary discharges caused by electrostatic charges in flexible containers such as flexible intermediate bulk containers (FIBCs) and (2) decreasing the induction on isolated conductors nearby the container to reduce the potential for incendiary discharges from the isolated conductors.
US10023372B2 Carton with handle and dispenser
A carton for holding a plurality of containers. The carton comprises a plurality of panels extending at least partially around an interior of the carton and a dispenser comprising a dispenser panel. The dispenser panel is at least partially defined by a tear line extending in at least one panel of the plurality of panels. The dispenser panel can be at least partially removable from the carton to create a dispenser opening. The carton also can comprise a handle for grasping and carrying the carton. The handle comprises a handle feature extending in at least the dispenser panel, and at least a portion of the handle can be removable from the carton with the dispenser panel.
US10023370B2 Dispensing device having a peripheral outer wall
A simple, cost-effective dispensing device is proposed which can be independent of a container. The dispensing device has a peripheral outer wall which defines a dispensing space. The dispensing space is closed by a tear-resistant film on the push-open side, whereas the cover side is closed by a cover plate which can be formed in one part with the peripheral outer wall. The dispensing space can be subdivided into chambers by connecting walls. The plunger can be used to successively push open the tear-resistant film and the active ingredients in the chambers are thus dispensed.
US10023369B2 Attachment for a liquid container
An attachment (1) for a liquid container with a container outlet, wherein the liquid container is surrounded by a container wall and is intended to receive a first liquid, wherein the attachment (1) has a bearing surface (2), which defines a bearing plane (A), for bearing in a sealing manner against the liquid container a reservoir (4) for a second liquid, a channel (6), which connects the container outlet to an outlet (10) of the attachment (1) and a passage (44), which connects the reservoir (4) to the channel (6), wherein the attachment (1) is equipped with a clamping lever (14), which extends in a use position through the bearing plane (A) and the container outlet and which has a pressing surface (32) facing the inner side of the liquid container in the use position.
US10023366B2 Beverage container closure
A beverage container closure or lid that is adapted for closing an open end of a beverage container. The lid is selectively couplable to the beverage container and includes a selectively openable stopper that when closed, creates a fluid-tight seal between the beverage container and the environment. The stopper may be selectively opened by a user by the user pressing a button disposed on a side of the beverage container closure. The stopper is subsequently automatically closed when the user releases the button. Thus, a user may open and close the beverage container closure using a single hand without the need to remove the beverage container closure from the beverage container.
US10023365B2 Drink bottles
Drink bottles, or drink containers with cap assemblies that include a drink spout. In some embodiments, the drink spout is pivotally coupled to a base of the cap assembly. In some embodiments, the drink spouts include mouthpieces, including self-sealing and/or bite-actuated mouthpieces. In some embodiments, the cap assembly includes a handle, which may include at least one guard for the drink spout and/or mouthpiece. In some embodiments, the drink containers include a manual on/off valve. In some embodiments, the dispensing spout includes a mount for the mouthpiece and/or cooperates with the cap to provide a manual on/off valve to selectively restrict flow of drink fluid from the drink container regardless of the drink spout's and/or mouthpiece's configuration. In some embodiments, the drink containers include a drink tube extending from external of the drink containers and/or an air return system.
US10023363B2 Lid and container assembly
A thermoplastic container assembly includes an improved means of attachment between lid, base and container which meets paint industry drop test standards and includes tamper evidence, a transparent lid and improved means to prevent leakage between the base, lid and container. The container includes an upper extending tubular wall element extending from the perimeter of a bottom wall to an upper rim, the upper rim including an annular inward facing cavity formed by a reduced thickness area, which includes an annular inward facing upper bead positioned above the inward facing cavity. A base includes an annular portion having an outwardly directed resilient exterior annular wall which engages the inward facing cavity of the rim of the tubular element in snap fit engagement. A lid includes a plurality of spaced apart resilient flange/protrusion elements extending outwardly from a bottom portion of an annular portion of the lid; the flanges/protrusion elements being snap-fit engageable within an upward facing annular groove of the base.
US10023362B2 Tube cosmetic container
The present invention provides a tube cosmetic container that can be used by a user effectively and comfortably in a process of grasping a container main part, a process of turning a cap, and a process of turning the cap again to close an opening of the container main part. A profile of a tube cosmetic container of the present invention is formed in a substantially spindle shape.
US10023360B2 Sealing bag for hydrogen gas, and method for dissolving hydrogen gas
The present invention aims at dissolving hydrogen gas in a liquid and maintaining the solubility of the hydrogen gas in the liquid at a high state.A sealing bag 1 that dissolves hydrogen gas in a liquid by being put into the liquid includes a hydrogen permeable film that can permeate hydrogen gas that is sealed and filled in the sealing bag to outside. By sinking this sealing bag 1 into the liquid in advance, the hydrogen gas that is permeated through the hydrogen permeable film is dissolved in the liquid. Furthermore, since the hydrogen gas is continuously permeated little by little through the hydrogen permeable film, the solubility of the hydrogen in the liquid can be maintained at a high state.
US10023358B2 Packaging for containers
This packaging is for containers having each a cylindrical body and an upper surface located at or near an extremity of the body, said packaging comprising a nest, a tub and a sealing cover; the nest having a nesting structure to receive the containers and comprising at least one first supporting surface, to be received on at least one corresponding supporting surface of the tub, the tub having a bottom wall, lateral walls forming an upper opening, and a peripheral flange leveled with said upper opening, for the sealing of said sealing cover thereon; said nest includes at least one second supporting surface rigidly connected to said at least one first supporting surface and so positioned with respect to this at least one first supporting surface that this second supporting surface is located, when the nest is placed in the tub, at the level of said peripheral flange.
US10023354B2 Pallet with extruded composite support blocks and associated methods of making the same
A pallet includes a cargo layer and a base layer, and a plurality of support block assemblies separating the cargo and base layers. Each support block assembly includes a first support block with a first opening extending therethrough in a horizontal direction, and a second support block inserted into the first opening of the first support block.
US10023348B2 Stackable container
A container for receiving foodstuff or dried beverages comprising a surrounding container wall, an upper container opening and a bottom part opposite to the container opening and connected to a lower end section of the container wall, wherein the bottom part includes an essentially flat bottom section and an abutment flange which protrudes at least in some locations from the bottom section in the direction of the container opening, and the lower end section of the container wall includes a support ring protruding radially inwards from the end section. The bottom part and the lower end section is connected between the abutment flange, an inner side of the container wall, and between the lower side of the bottom section and an upper side of the support ring.
US10023343B2 Automatic taking-out method and device for packaged contents
An automatic taking-out device is configured by providing a package holding unit that holds the package; a cutting unit that cuts the two packaging sheet materials of the package in a held state in two cutting spots that are respectively present between the joining portions and the contents and that face each other with the contents therebetween; a pair of suction units that respectively suction and hold the two packaging sheet materials inside the two cutting spots; a driving unit that moves at least one of the suction units in a direction separated from the contents; and an inclining unit that inclines the two packaging sheet materials inside the two cutting spots and the contents in a state where a positional deviation in an up-down direction occurs with respect to the two cutting spots, and drops the contents out of the two packaging sheet materials.
US10023340B2 Paper sheet processing device
Disclosed herein is a paper sheet processing device 100 including: a hopper unit 2 configured to take in paper sheets; a recognition unit 3 configured to read serial numbers of the paper sheets taken in through the hopper unit 2; a database 1202 configured to store the serial numbers read by the recognition unit 3; and a control unit 120 configured to process the paper sheets. The control unit 120 searches the serial numbers stored in the database 1202 for any duplicated serial number, and detects, when finding any duplicated serial number, that duplicate processes have been performed on a paper sheet identified by the duplicated serial number.
US10023334B2 Full motion wrapping apparatus
A full motion wrapping apparatus includes a wrapper unit and a product support unit. The wrapper unit is configured for stretch wrapping a product. The product support unit includes a plurality of supports. The supports are movably disposed in, on or around a track with the wrapper unit. The wrapper unit may be positioned between corresponding pairs of the supports. The product support unit permits the stretch wrapping of the product while the product remains in a substantially stationary position.
US10023333B2 Vacuum assisted nozzle and apparatus
An apparatus having a nozzle, a fluid flow conduit, a fluid flow discharge opening, a fluid flow discharge opening area, a fluid flow valve, a vacuum, a vacuum conduit, a vacuum opening, a vacuum valve, and a vacuum opening area wherein the vacuum opening is spatially proximate to the fluid flow discharge opening, the vacuum opening area to the fluid flow discharge opening area has a ratio of less than or equal to 1, and the fluid flow valve and vacuum valve are coupled.
US10023332B2 Continuous rotary machine for filling capsules with pharmaceutical products
A continuous rotary machine for filling capsules with pharmaceutical products is provided with at least one dosing wheel having a plurality of pockets each defined by a respective upper seat, which is suited to receive and hold a closing cap of a capsule and by a respective lower seat, which is suited to receive and hold a bottom of the capsule, and is provided with a measuring device to measure the weight of the bottom or of the bottom and of the pharmaceutical product contained in the lower seat itself; the upper seat being radially mobile between a forward position, in which the lower and the upper seats are vertically aligned with each other, and a retracted position, in which the lower and the upper seats are vertically staggered with respect to each other.
US10023331B2 Continuous conveying type bag filling and packaging machine
A continuous conveying type bag filling and packaging machine including multiple groups of grippers (2) continuously traveling along a racetrack-shaped annular path and, as the grippers (2) complete a single revolution, carries out various packaging operations, wherein a measuring hopper (42) is provided above each elevating hopper (37) and is continuously rotated in conjunction therewith. The measuring hopper (42) has a shutter (44). A weight detector (46), along with a shutter actuation mechanism (47), is provided so as to correspond to each measuring hopper (42) and is continuously rotated in conjunction therewith. If, based on a detection signal from the weight detector (46), it is determined that the weight of the material to be packaged that is supplied to the measuring hopper (42) exceeds the upper limit value of the allowable range, the corresponding shutter actuation mechanism (47) is not actuated, and the shutter (44) is maintained closed.
US10023330B2 Yarn packaging and delivery system
Included are apparatus and methods for preparing a yarn package for a small portion of yarn that provides substantially uniform tension on removal. The method includes providing an amount of yarn up to two pounds which is introduced to a small package with vacuum applied at the bottom of the container and vibration to assist yarn uniform packing of the yarn.
US10023321B1 Method and apparatus for forming barriers within cavities
A barrier is installed within an elongate cavity in a structure. Spaced apart walls are installed within the cavity, and the cavity between the walls is filled with a sealant. The sealant is allowed to cure, following which the walls are removed.
US10023317B2 Flight deck takeoff duct and trim air mix muff
An exemplary ventilation air mixer includes a branch air duct and a trim air mixer. The branch air duct has an inlet that is configured to be coupled to a takeoff port of a main air source duct. The branch air duct has multiple holes arranged about a wall of a mixing portion. The trim air mixer at least partially surrounds the branch air duct and forms a cavity extending from the inlet of the branch air duct to at least the mixing portion. The trim air mixer has a trim air source duct connection coupled at an angle about a midsection. The angle is substantially acute relate to a longitudinal axis of the branch air duct such that trim air entering into the trim air mixer via the trim air source duct connection is directed toward the inlet of the branch air duct.
US10023310B2 Unmanned flying object and flight control method thereof
A flight control method of an unmanned flying object includes acquiring first positional information indicating a position of the unmanned flying object using a position sensor, receiving a position reset command and second positional information that indicates a position of an operation device from the operation device used to operate the unmanned flying object, determining a rotation angle needed to orient a movement direction of the unmanned flying object in a predetermined direction in accordance with the first positional information and the second positional information, and performing control to orient the movement direction of the unmanned flying object in the predetermined direction in accordance with the rotation angle.
US10023308B1 Tethering system and method for remote device
A tethering system for a remote-controlled device includes a tether line having a first end adapted to be connected to a ground support and a second end adapted to be connected to the remote-controlled device. The system further includes an anchor-point disposed between the first and second ends of the tether line, the anchor point having an eyelet for securing the tether line and allowing the tether line to slide through the eyelet during use. The anchor-point and eyelet enable the tether line to flex or bend and the remote-controlled device to maneuver one or more of over or around the target area without interfering with any nearby obstructions.
US10023299B2 Propeller blade for an aircraft engine
The disclosure refers to a propeller blade for an aircraft engine that includes an airbag system contained inside the blade and comprising at least one bag and at least one gas generator, the at least one gas generator in fluid communication with at least one bag for inflating the bag, a detecting system for detecting a rupture of a part of the blade, a trigger for activating the at least one gas generator when the rupture is detected by the detecting system, and the blade skin being configured for allowing the at least one bag to pass through the blade skin for being expanded outside the blade upon the bag inflation by the gas generator.
US10023296B2 Inlet duct selector for tiltrotor barrier filter
The present invention includes an air flow bypass for a tiltrotor engine comprising: a ram air inlet comprising bypass door(s) capable of at least partially or fully blocking a ram air flow through the ram air inlet; a barrier filter inlet positioned in a side, a bottom, and/or a top of a tiltrotor engine nacelle; a filter plenum; a selector duct comprising one or more openings; and one or more selector duct doors or covers over the one or more openings; wherein the barrier filter inlet, the filter plenum, the one or more openings in the selector duct, the selector duct, and an engine are in fluid communication and the bypass door(s) in the ram inlet are closed and the barrier filter inlet provides filtered air flow to the engine when the aircraft is in hover operations.
US10023294B2 Tail spar spring
According to one embodiment, an empennage attachment system features an aft attachment mechanism and a forward attachment system. The aft attachment mechanism is configured to be coupled to a tail section of a body of an aircraft and to an empennage proximate to an aft spar of the empennage. The aft attachment mechanism defines a pitch axis such that the aft attachment mechanism allows the empennage to rotate about the pitch axis. The forward attachment system is configured to be coupled to the tail section of the body and to the empennage proximate to a forward spar of the empennage. The forward attachment system is configured to restrict rotation of the empennage about the pitch axis to an allowable range of motion.
US10023287B2 Method for manufacturing a shell element reinforced with support elements
A method for manufacturing a shell element reinforced with support elements comprises providing a skin element that has an outer surface and an inner surface opposite the outer surface, providing a first support element that has an attaching side and a free side opposite the attaching side, attaching the first support element on the skin element such that the attaching side of the first support element faces the inner surface of the skin element. A first recess is introduced into the first support element that proceeds from the free side of the first support element and extends transversely to the first axis. A second support element is provided that has a support side and a front side opposite the support side. The second support element is inserted into the first recess of the first support element such that the support side faces the inner surface of the skin element.
US10023286B2 Aircraft bay blankets that provide enhanced drainage features
Systems and methods are provided for insulation and moisture drainage. One exemplary embodiment is an apparatus comprising a bay blanket configured to insulate an aircraft. The bay blanket includes insulation, and a first waterproof lip that protrudes from the insulation in an outboard direction towards a frame of the aircraft and extends along a length of a leftward side of the bay blanket. The bay blanket also includes a second waterproof lip that protrudes from the insulation in an outboard direction towards the frame of the aircraft along a length of a rightward side of the bay blanket.
US10023284B1 Outboard motor
An outboard motor includes an electric power source, a mechanical power source auxiliary machine, an electric circuit, an electric supply port, and a switch. The mechanical power source auxiliary machine assists driving a mechanical power source. The electric circuit electrically connects the electric power source and the mechanical power source auxiliary machine. The electric supply port is electrically connected to the electric power source through the electric circuit, and supplies an electric power to an accessory device to be connected thereto. The switch is disposed between the electric power source and the electric supply port in the electric circuit, and is switchable between an on state and an off state. The switch allows a flow of an electric current when switched to the on state, and interrupts the flow of the electric current when switched to the off state.
US10023280B2 Device for winding and unwinding a cable around a drum
A device for winding and unwinding a cable including a winch comprises a chassis, an electric motor for driving a drum in rotation in relation to the chassis, locking/unlocking means comprising a first induction coil and configured such as to immobilize the drum in relation to the chassis when the first coil is not being powered electrically, the device including a second induction coil that is powered electrically, dimensioned and arranged such that the magnetic field generated by the assembly formed by the first and second coils, when the first coil is powered electrically, is less than the magnetic field generated by the first coil at a point located at a distance from the winch that is greater than a predetermined threshold, the electrical energizing and de-energizing of the second coil being synchronized with the electrical energizing and respectively de-energizing of the first coil.
US10023276B1 Canoe outrigger with built-in storage capacity
A canoe outrigger with built-in, covered, storage capacity. Unlike a typical pontoon type outrigger, this device is a miniature canoe form that has an open interior. The top of the outrigger has three doors allowing for storage and access within the form that holds many supplies, such as camping and fishing gear, food, water and other items. The outrigger is connected to a canoe, or other small boat, by a pair of telescoping arms. Each arm has clamps that secure the arms the gunwales of the vessel. The other end of each arm is bolted into position on the outrigger. In this way, the outrigger is securely attached for use.
US10023275B2 Selectively deployable fin system for watercraft and method of use
The present application is directed to a selectively deployable fin system which includes at least one housing positioned within a body of a standup paddleboard, the housing defining at least one housing passage therein, at least one actuator is positioned within the housing. The actuator is configured to be operable by a user positioned on the standup paddleboard or similar watercraft during use. At least one linkage system, in communication with the actuator, is positioned within the housing. In addition, at least one fin is in communication with the actuator via the linkage device. The fin is configured to be selectively positioned within the housing in a retracted configuration and selectively extending from the housing in a deployed configuration.
US10023268B2 Moonpool work table
A moonpool work table able to provide an opening to a moonpool including a first set of opposing table doors having opposing vertical faces and moveable between an open position and one or more closed positions, and a second set of opposing table doors moveable between an open position and one or more closed positions in a transverse direction to that of the first set of table doors. In this way, the first and second set of table doors are able to define a “box” that can more closely and tightly define the area or envelope through which a conduit or the like can pass.
US10023267B2 Polymer drag reduction systems on vehicle surfaces
Systems and methods of reducing drag on outer surfaces of vehicles that are in contact with water using a polymer solution that reduces the drag on the outer surfaces of the vehicles as the vehicles travel through water. A polymer solution is passively ejected into the boundary layer of the water flowing past the outer surface of the vehicle. The polymer solution is mixed and introduced into the boundary layer passively with minimal or no usage of electrical energy. The passive mixing and ejection of the polymer solution minimizes energy consumption, thereby maximizing electrical energy consumption efficiency during operation of the vehicle.
US10023261B2 Motorcycle trailer
A motorcycle trailer that includes a box trailer bed. The motorcycle trailer also includes a hinged lift lid, the lift lid including aerodynamic curvature on the front top and rear top. The motorcycle trailer additionally includes at least one lid latch positioned and structured on the off-road side of the hinged lift lid for fastening and unfastening the hinged lift lid closed selectively and the hinged lift lid having lid curvature corresponding to the aerodynamic curvature of the front top and the aerodynamic curvature of the rear top of the box trailer bed. The motorcycle trailer also includes the box trailer bed being affixed to a trailer frame, a road-side wheel suspended from the roadway side of the trailer frame with a road-side spring member and an off-road-side wheel suspended from the off-road side of the trailer frame with an off-road-side spring member.
US10023259B2 Accessory for a self-balancing board
An accessory for a self-balancing board is provided. The self-balancing board comprises a foot-deck having two lateral foot-deck ends. Each lateral foot-deck end is coupled to a motor that drives a wheel in response to an orientation of the lateral foot-deck end relative to a horizontal plane. The accessory includes a chassis, at least one travel surface-contacting element coupled proximal to a first longitudinal end of the chassis to facilitate travel of the chassis over a travel surface, and a seat coupled to the chassis and configured to support a person. The accessory further includes a first foot-deck engagement element proximal to a second longitudinal end of the chassis distal to the first longitudinal end and constructed to engage the foot-deck of the self-balancing board proximal to the first lateral foot-deck end, and a second foot-deck engagement element proximal to the second longitudinal end of the chassis and constructed to engage the foot-deck of the self-balancing board proximal to the second lateral foot-deck end. At least one control member coupled to the first foot-deck engagement element and the second foot-deck engagement element controls the orientation of the lateral foot-deck ends relative to a horizontal plane via the first foot-deck engagement element and the second foot-deck engagement element.
US10023257B2 Waterproof end cap for bicycle frame member
A waterproof end cap for covering and closing an end hole of a bicycle head tube includes a threaded locking base, a locking member, and a sealing cover. The threaded locking base is engaged in the end hole. The locking member has large- and small-diameter portions. The end of the large-diameter portion that faces away from the small-diameter portion has an outwardly extending annular plate. The small-diameter portion is externally threaded, extends into the end hole, and threadedly connects with the threaded hole of the threaded locking to base such that the annular plate is pulled to cover the end hole. The sealing cover is larger than the annular plate in diameter and has opposite first and second sides. The first side is free of water-holding spaces. The second side covers the annular plate detachably through elastic engagement. Water can neither accumulate on nor leak through the sealing cover.
US10023256B2 Streamline storage system
Disclosed is a streamlined storage system for use with a motorcycle or other similar vehicle seat that does not detract from the riding experience, that is easy and convenient for the rider to access while riding, and that does not substantially increase the overall cost of the vehicle.
US10023253B2 Bicycle fork protector
A bicycle fork protector and stand comprising a wheelset having at least one or two miniature wheels and an axle on the wheelset for engaging a bicycle fork at the bicycle dropouts to protect the fork from damage and maintain the fork blades in a correct spatial arrangement for storage and/or transport of the bicycle.
US10023250B2 Multi-tread vehicles and methods of operating thereof
Provided are multi-tread vehicles and methods of operating such vehicles to access small interior spaces. A multi-tread vehicle may include two or more tread sections such that each pair of adjacent tread sections is interconnected by a connector section. Furthermore, each pair may have one or more degrees of articulations, such as being pivotable with respect to each other around one or more axis and/or being bendable with respect to each other around one or more axis. These articulation degrees may be provided by the connector section and/or by couplings between the connector section and each tread section. In some embodiments, each tread section may include two portions detachably coupled to each other. This detachable coupling may be used for disassembly of the multi-tread vehicle after or even during its use, for example, when only a portion of the vehicle needs to be retrieved from an interior space.
US10023246B2 Press-formed product, automobile structural member including the same, production method and production device for the press-formed product
A bulkhead, which is a press-formed product, includes a top plate part, side flange parts and corner flange parts. The side flange parts each extend from respective sides of the top plate part. The corner flange parts each extend from respective corner parts of the top plate part. The corner flange part connects the side flange parts to each other. In the corner flange part, a part having a minimum value of plate thickness is present in a central portion in a circumferential direction, and parts having a maximum value of the plate thickness are present on both sides thereof. A ratio of the maximum value and the minimum value is in a range of more than 1.0 to 1.6 or less.
US10023234B2 Arcuate frame for a vehicle
An All-Terrain Vehicle with a frame comprising an arcuate shape or an elevated portion with an apex. In one embodiment, the arcuate shape or elevated portion with an apex is located between a rear axis and a front axis such that there is additional clearance over a typical non arcuate frame or a flat frame for a given ride height. The arcuate shape may be a lateral arcuate shape. The frame may also provide for additional structural strength. The frame may also include the ability to attach periphery accessories such as an engine cage, a passenger cage, trailing arms, power train and transmission.
US10023233B2 Auxiliary frame for supporting a front suspension of a motor-vehicle
An auxiliary frame for supporting elements of a front suspension of a motor-vehicle includes two end supports for connection thereto of suspension elements and a structure which connects the end supports to each other. The connecting structure has a front beam and a rear beam which connect the end supports to each other. The rear beam has an arch-like configuration which extends substantially in a horizontal plane, with a central portion arranged in a forwardly spaced position. The front beam of the connecting structure has a configuration which is substantially straight and perpendicular to a vertical median plane of the auxiliary frame. The front beam and the rear beam are longitudinally spaced from each other and connected to each other by at least two lateral longitudinal arms spaced from each other and which have a configuration substantially straight and parallel to the vertical median plane of the auxiliary frame.
US10023232B2 Vehicle body front structure
A vehicle body front structure includes: a bracket 21 that is placed on a lower portion of a front side frame 12; and a front subframe 16 that is attached to a lower portion of the bracket with a bolt 22. The bracket includes: a closed-end hollow bracket body 30 that is suspended from the front side frame; a bulkhead 40 that is located above a bottom plate 31 of the bracket body and vertically partitions the bracket body; and a collar 50 that extends from the bulkhead to the bottom plate of the bracket body. A thickness t2 of the bulkhead is smaller than a thickness t1 of the bracket body. The bulkhead joined to the bracket body has a bulkhead-side flange 44 joined to the front side frame.
US10023231B2 Parking autonomous vehicles
Technology is described for parking autonomous vehicles. An autonomous vehicle may receive an instruction to park the autonomous vehicle. The instruction may be received when the autonomous vehicle is in a preselected location. The autonomous vehicle may select at least one parking area that potentially has available parking spaces to park the autonomous vehicle using, in part, a defined set of parking criteria. Commands may be provided to drive the autonomous vehicle to the parking area. The autonomous vehicle may be configured to select an available parking space within the parking area to park the autonomous vehicle. The autonomous vehicle may send a confirmation message after the autonomous vehicle is parked in the available parking space within the parking area. The confirmation message may include a parking location associated with the autonomous vehicle.
US10023227B2 Steering assistance control apparatus
A steering assistance control apparatus includes a positional deviation calculator, a relative yaw angle calculator, a target value calculator, and a steering driver. The positional deviation calculator calculates a lateral positional deviation between an own vehicle and a preceding vehicle, based on a detection signal by a sensor. The relative yaw angle calculator calculates a relative yaw angle, in which the relative yaw angle is an angle formed by a traveling direction of the own vehicle and a traveling direction of the preceding vehicle. The target value calculator calculates a steering-related control target value, based on the lateral positional deviation and the relative yaw angle. The steering driver that drives a steering mechanism, based on the control target value.
US10023225B2 Apparatus and method for controlling motor-driven power steering system
An apparatus and a method for controlling a motor-driven power steering system can inhibit a change in steering feeling which may be caused by abrasion and degradation of components in the motor-driven power steering system, and maintain initial steering feeling. The method determines a torque compensation amount by comparing a reference value with change ratio average data of steering torque with respect to a steering angle, and compensates for driver input torque in accordance with the determined torque compensation amount, such that it is possible to effectively inhibit the change in steering feeling which may be caused by abrasion and degradation of components, and maintain the initial steering feeling.
US10023220B1 Cart ski system
A cart ski system for urging a cart along a granular support surface includes a cart that may be rolled along a support surface. The cart has a set of rear wheels and a set of front wheels. A pair of skis is provided and each of the wheels is positioned in a corresponding one of the skis. Each of the skis slides along the support surface when the support surface is comprised of a granular material thereby enhancing urging the cart along the granular material.
US10023219B2 Snow surface skimmer
The snow surface skimmer is provided with: a skimmer body; a steering handle, which extends upward at a slant from the skimmer body; a seat installed on a region of the skimmer body that is behind the steering handle; and a skimming board. The skimming board is detachably attached to the bottom surface of the skimmer body by a skimmer attachment mechanism so that the attachment position in the front-back direction is adjustable. A skimming board suited to the skimming person's body type, build, etc. can be attached to the skimmer body at the appropriate position in the front-back direction.
US10023216B2 Cart monitoring system capable of authorizing cart exit events
A system for monitoring shopping carts or other human-propelled carts includes wireless access points that communicate on a wireless network with wheel assemblies of the carts. The system is capable of monitoring a path followed by a cart in a store or building, and using the path (optionally together with other criteria) to determine whether to authorize the cart to exit. For example, if a shopping cart fails to pass through a checkout lane of a store, the system may perform an action that blocks or inhibits the shipping cart from exiting the store.
US10023213B1 Disc golf transport system
A disc golf transport system to allow the movement of disc golf paraphernalia about a course utilizing existing or specialized backpacks. The system uses a three wheeled manual pull cart that has a five point adjustable suspension system incorporating two adjustable, lockable upper arms with peg horns extending therefrom; two pivotable lower arms with length and angle adjustable means for attachment; and a central attachment member. All of the five attachment points allow an attached packpack to be drawn taut from five different points so as to secure, and position the bag in the cart for both easy content access and maximum transit stability.
US10023212B2 Hand truck with an adjustable wheel axle
Hand truck with an adjustable wheel axle suitable for manual transport of heavy objects, comprising: an elongate and substantially planar main frame, a load plate fixedly connected to the front side of the main frame and at the lower end, an axle suspension comprising a rigid body which is fixedly connected to the rear side of the main frame and close to the lower end; a wheel axle, both ends of which are provided with a wheel and which is disposed rotatably inside the axle suspension, wherein the axle suspension comprises a guide for guiding the wheel axle over a path between a low and a high stop.
US10023211B2 Train position detecting device
A train position detecting device includes: a GPS position guarantee range calculation part for calculating, based on a result of measurement of a position of a train by GPS signals; a tachogenerator-position guarantee range calculation part for calculating, based on a result of measurement of a position of the train by a tachometer generator that measures a relative distance from a measurement carried out previously; and a position determination part that determines, between an end part of the GPS position guarantee range in the first-direction and an end part of the tachogenerator-position guarantee range in the first-direction, a position of an end part on the positive side of the second direction to be a position of the end part of the train in the first-direction.
US10023206B2 Railroad hopper car and door mechanism therefor
A railroad hopper car discharge outflow is controlled by closure members, at least one of which is movable. The closure members (or doors) are hingeless, being mounted on four bar linkages, such that the distal edge of the doors sweeps predominantly horizontally while the proximal edge of the door moves predominantly upwardly. The doors move through noncircular arcs, such that the size of the vertically projected door opening is abnormally large compared to the clearance heights of the door during opening and closing. The doors are driven by a transverse drive linkage that is driven by a transversely mounted actuator. The actuator may be mounted in an accommodation in the lee of slope sheets between adjacent hoppers in a mid-span portion of the car. Drive from the actuator is carried to a pair of symmetrically mounted doors through drive train linkages.
US10023202B2 Steering and traction applications for determining a steering control attribute and a traction control attribute
Based on a steering control input, a measured value of the steering control attribute and a measured value of the traction control attribute received by a steering application, determining: a first setpoint value of the steering control attribute; a target steering angle of the steered wheel of the vehicle. Based on receiving, by a traction application executing on the vehicle control module of the vehicle: a traction speed control input to control the traction wheel of the vehicle, and the target steering angle, from the steering application, determining, by the traction application: a second setpoint value of the traction control attribute.
US10023201B1 Systems and methods for proximate event capture
A method includes collecting first data from a first sensor associated with a vehicle and determining, based on the first data, that an event involving the vehicle may occur. The method includes identifying a second sensor located within a proximity of the vehicle and causing the second sensor to collect second data. The method also includes associating the first data and the second data with a first event associated with the vehicle.
US10023199B2 Method and device for ascertaining a state of drowsiness of a driver
A method for ascertaining a state of drowsiness of a driver of a motor vehicle, movements of at least one eyelid of one eye of the driver being detected, and the state of drowsiness of the driver being determined as a function of the detected movements. It is provided that an instantaneous normal degree of eye opening is determined, that closing movements of the eyelid are monitored based on the normal degree of eye opening, and that the state of drowsiness is determined as a function of the detected closing movements.
US10023198B2 Method for determining a relative gradient of a roadway
A method for determining an incline in a road that is some distance ahead of a motor vehicle relative to the section of road that is currently being driven on by the motor vehicle, wherein images of the road that is ahead of the motor vehicle are recorded by a camera, road path lines are identified ahead of the motor vehicle in the recorded images and the relative incline is calculated with reference to the differences in the courses of the road path lines at different distances.
US10023195B2 Powertrain operation and regulation
One or more powertrains can include a motor-generator disposed therein that is electrically coupled to an energy storage device through an inverter gate. A regulation strategy can monitor operation of the powertrain to regulate the inverter gate to selectively discharge energy from the energy storage device to the motor-generator to assist the powertrain or to charge energy from the motor-generator to the energy storage device for future use. In an aspect, the regulation strategy may maintain a consistent speed of an internal combustion engine associated with the powertrain. In another aspect, the regulation strategy may regulate simultaneous operation of first and second powertrains disposed a parallel relation.
US10023194B2 Method and system for controlling a vehicle powertrain
The invention relates to a method of controlling a vehicle powertrain including determining that a performance feature associated with the powertrain is outside of a desired performance range. A plurality of operation parameters that are associated with the powertrain are identified that have a relationship to the performance feature. An adjustment is automatically made to at least one of the identified operation parameters to thereby bring the performance feature closer to the desired performance range. Preferably, the relationship comprises a mathematical model that corresponds to how the operation parameters influence whether the performance feature is within the desired performance range, the method further comprising identifying an actuator failure associated with the powertrain; determining at least one of the operation parameters corresponding to the actuator failure; determining a value of the corresponding operation parameter that is indicative of the actuator failure; and using the determined value as a fixed value for the corresponding operation parameter in the mathematical model.
US10023192B2 Vibration control device and vibration control system
A vibration damping control device that controls drive output of a vehicle so as to suppress pitch/bounce vibration of the vehicle includes a vibration damping control unit that controls driving torque of the vehicle so as to reduce an amplitude of the pitch/bounce vibration, based on wheel torque applied to wheels of the vehicle and generated at a location where the wheels contact with a road surface, and a compensation component adjusting unit that reduces an amplitude of a compensation component that corrects the wheel torque calculated by the vibration damping control unit so as to suppress the pitch/bounce vibration, as the magnitude of the steering angle velocity of the vehicle increases.
US10023190B2 Method and control for operating a transmission in neutral
A vehicle powertrain includes an engine and a transmission coupled to the engine. The transmission has a first neutral state in which a first combination of clutches are engaged and a second neutral state in which a second combination of clutches are engaged. A vehicle controller is programmed to, in response to the transmission being in the first neutral state and an engine-torque request exceeding a threshold value, shift the transmission to the second neutral state.
US10023183B2 Method of controlling engine speed of hybrid vehicle
A method of controlling an engine speed of a hybrid vehicle including a motor that is connected to a transmission, a battery that provides a driving voltage to the motor, an engine that is selectively connected to the motor through an engine clutch, and a hybrid starter-generator (HSG) that is connected to the engine includes: comparing, when the engine is started, an external air temperature to a setting temperature; setting a battery rated derating factor based on the comparison of the external air temperature to the setting temperature; determining an output area of the HSG according to a battery voltage; and outputting an available torque of the HSG based on the set battery rated derating factor and the determined HSG output area.
US10023180B2 Control device and control method for vehicle
A control device for a vehicle includes an electronic control unit. The electronic control unit is configured to set a share ratio of driving force of the first electric motor and the second electric motor. The electronic control unit is configured to set the share ratio of the driving force such that when the temperature of a pinion gear in a planetary gear mechanism is higher than a specified temperature, the share ratio of the driving force of the first electric motor is lower than the share ratio when the temperature is lower than the specified temperature.
US10023177B2 System and method for engine starting in a hybrid vehicle based on engine stop position
A system and method for controlling engine starting in a hybrid vehicle having an engine, a first electric machine selectively coupled to the engine by a first clutch, a second electric machine coupled to the engine, a step-ratio transmission selectively coupled to the electric machine by a second clutch include starting the engine using either the first electric machine or the second electric machine based on engine stop position. The first electric machine may be a low voltage starter motor or integrated starter-generator. The system and method may use the first electric machine when the engine stop position is within a specified range of positions relative to a piston top dead center position associated with higher cranking torques.
US10023176B2 Method and device for forecasting the range of a vehicle with an at least partially electric drive
A method for predicting a range of a vehicle having an at least partially electric drive. When a first operating mode of the vehicle is ended at a time, the vehicle switches into a second operating mode when the first operating mode ends. The range of the vehicle is determined when the first operating mode ends. Starting at the time at which the first operating mode ends, the temporal development of a parameter from the surroundings of the vehicle is determined for a certain duration, wherein the vehicle is in the second operating mode for at least a portion of the certain duration. Also disclosed is a device for predicting a range of a vehicle having an at least partially electric drive.
US10023175B2 Optimal engine operating power management strategy for a hybrid electric vehicle powertrain
A method for managing power in a hybrid electric vehicle powertrain having multiple components including at least two of a group comprising an engine, a motor, a generator and a high voltage battery includes computing power losses for the individual components. An engine operating speed and torque for a given vehicle speed and total power command is determined so that total power losses for powertrain components are minimized.
US10023174B2 Methods and systems for hybrid vehicle power delivery
Methods and systems are provided for adjusting engine operation of a hybrid vehicle to increase power output and fuel efficiency. In one example, a method may include operating the engine using an Atkinson cycle during a lower than threshold engine torque demand and a lower than threshold battery state of charge, and operating the engine using an Otto cycle during a higher than threshold torque demand. During operation in the Otto cycle, an octane booster is injected to the fuel line to increase the octane level in the fuel, if desired.
US10023173B2 Electromotive drive system for engine-driven vehicle
An electromotive drive system including a small motor and a small-capacity battery more effectively improves the fuel economy of an engine-driven vehicle. An electromotive drive system includes: a motor for driving a vehicle; a battery storing electrical energy to rotate the motor; an inverter; a converting mechanism transmitting rotation of the motor to a drive shaft at a predetermined conversion ratio independently of a conversion ratio at which an engine is driven; and a control unit controlling an operation of the inverter. The control unit is configured so that upper vehicle speed limits, to which the motor is allowed to operate, can be set separately during powering and during regeneration, respectively.
US10023172B2 Method of starting a combustion engine of a driving vehicle
In a method for controlling a vehicle with a drive system comprising an output shaft of a combustion engine and a planetary gear with a first and a second electrical machine, connected via their rotors to the components of the planetary gear, the combustion engine is started while the vehicle is driven by ensuring that the rotor of the second electrical machine is connected with the output shaft of the combustion engine, and controlling such electrical machine's rotational speed towards the combustion engine's idling speed, whereupon fuel injection into the combustion engine is carried out to start the latter.
US10023168B2 Hydraulic power unit and braking system for a vehicle
A hydraulic power unit for a braking system of a vehicle, including a first sub-brake circuit or brake circuit and a second sub-brake circuit or brake circuit, a first supply line branching into a first line section having a first circuit separating valve situated therein, and a second line section having a first electrically controllable reservoir separating valve and/or first check valve situated therein, and a second supply line branching into a third line section having a second circuit separating valve situated therein and a fourth line section having a second electrically controllable reservoir separating valve and/or second check valve situated therein.
US10023161B2 Braking control system for vehicle
An automatic emergency braking system for a vehicle includes a forward viewing camera and a control. At least in part responsive to processing of captured image data, the presence of another vehicle closing on the subject vehicle is determined, and a relative speed of the subject vehicle relative to the other vehicle is also determined. Responsive at least in part to a speed of the subject vehicle and the determined relative speed, the control controls the subject vehicle's brake system. Responsive to determination that the driver of the subject vehicle is impaired, the automatic emergency braking system does not allow the driver to override the control's control of the subject vehicle's brake system. Responsive to a determination that the driver of the subject vehicle is not impaired, the automatic emergency braking system allows the driver to override the control's control of the subject vehicle' brake system.
US10023158B2 Anti-theft vehicle brake
An anti-theft vehicle brake including a lockable restraining hub coupled to a wheel. The lock's default state being engaged and preventing rotation of the wheel. The lock including a solenoid bolt controlled through the communication of authenticating information sent from a transmitter and recognized by a receiver, triggering the disengagement of the bolt from the restraining hub allowing rotation of the wheel.
US10023156B2 Washing tunnel for motorcycles
Washing facility for two- or three- wheeled vehicle where the vehicle is conveyed longitudinally by mechanical means opposite washing devices, where the facility comprises a lower longitudinal guiding device in order to guide a wheel of the vehicle on the floor along the longitudinal displacement thereof and an upper guiding device made firmly connected to the handlebars of the vehicle in order to keep the vehicle in vertical position.
US10023154B2 Universal connector for attachment of a windshield wiper blade with multiple types of windshield wiper arms
A connector for connecting a wiper blade and multiple types of wiper arms, the connector including a base for attachment to a wiper blade. The connector further includes a receiving element attached to the base, the receiving element having a structure to receive and be connected to at least six different wiper arms.
US10023152B2 Method of preventing a windshield wiper from freezing to a windshield and related circuit
A method of preventing a windshield wiper from freezing to a windshield of a vehicle is provided. The method broadly includes the steps of: (a) receiving information relating to an ambient condition of the vehicle; (b) switching power to a motor for driving the windshield wiper in a first direction if the received information indicates an adverse ambient condition of the vehicle; (c) sensing current drawn by the motor; (d) comparing an initial sensed current drawn by the motor when power is initially switched to the motor to a subsequent sensed current drawn by the motor a period after power is initially switched to the motor; and (e) periodically reversing the motor for driving the windshield wiper in a second direction or the first direction until the subsequent sensed current is less than the initial sensed current.
US10023151B2 Autonomous vehicle security
Various implementations include unmanned autonomous vehicles (UAVs) and methods for providing security for a UAV. In various implementations, a processor of the UAV may receive sensor data from a plurality of UAV sensors about an object in contact with the UAV. The processor may determine an authorization threshold based on the received sensor data. The processor may determine whether the object is authorized based on the received sensor data and the determined authorization threshold.
US10023149B2 Vehicle occupant protection device
A vehicle occupant protection device includes a front airbag and a lateral airbag. The front airbag is provided in a vehicle body and deploys in front of an occupant boarding the vehicle body so that at least a head of the occupant hits against the front airbag. The lateral airbag is provided in the vehicle body so as to deploy at a lateral side of the occupant. The lateral airbag has a protrusion that deploys toward a middle of the vehicle body in a width direction. The protrusion is deployed together with the front airbag so that the head of the occupant hitting against the front airbag is supported from front and lateral sides.
US10023140B2 Bumper assembly with closing plate
A bumper assembly for a motor vehicle comprising a cross member that extends transverse the motor vehicle, and has an open hat-shaped hollow profile with a rear-sided web and legs, extending from the web, wherein flanges extend from a free end of the legs in the vertical direction; and an opening pointing away from the motor vehicle, in the longitudinal direction. At least one closing plate is arranged allowing the opening to be completely closed in the vertical direction and arranged allowing a partial length of less than 50% of the length of the opening to be closed in the transverse direction; and that the flanges are offset from each other with an offset in the longitudinal direction; and that the cross member has a varying cross section over its length, wherein a central region is offset upwards from the end regions with a height offset to the vertical direction.
US10023137B2 Cable assembly for an electric vehicle that includes floor supported and sub-floor components
A power supply cable including high voltage wires and connectors for a traction motor, charger, upper battery pack and lower battery pack. The power supply cable includes a clamshell shield housing that protects the cable as it is routed over a rear seat pedestal. A two-piece grommet is provided to seal between the passenger compartment and the underbody of the vehicle and includes a rigid attachment ring and a seal that seals the passenger compartment from the environment below the vehicle.
US10023134B2 Wiring harness attaching structure
An object of the present invention is to provide a wiring harness attaching structure aiming at improvement in attaching workability and aiming at thinning of a vehicle door. Provided is a wiring harness attaching structure for attaching a wiring harness to a vehicle interior outer surface of a door trim constituting a vehicle door. The wiring harness is a flat cable whose width dimension is longer than a thickness dimension, is located inside a structure body containing gas phase, and is provided integrally with the structure body containing gas phase. The structure body containing gas phase is attached along the vehicle interior outer surface of the door trim. The wiring harness is attached to the door trim together with the structure body containing gas phase.
US10023133B2 On/off switch arrangement for a pivotable display screen in a motor vehicle
An ON/OFF switch arrangement is for a display screen pivotably mounted within a motor vehicle. The arrangement includes a mounting bracket retaining the display screen and pivotably attached to the motor vehicle such that the mounting bracket may be pivoted about an axis. A switch assembly includes a rotor attached to the mounting bracket. A contactor is attached to the rotor. A base is attached to the motor vehicle such that the rotor and the contactor rotate about the axis relative to the base when the mounting bracket is pivoted. The base has two spaced apart electrical contacts. The contactor electrically interconnects the two contacts within a first range of rotational positions of the rotor, and the contactor does not interconnect the two contacts within a second range of rotational positions of the rotor.
US10023127B2 Vehicle interior component
A vehicle interior component is disclosed. The vehicle interior component is an overhead console assembly for a vehicle interior. The overhead console may comprise a bezel/base and a storage member coupled to the bezel. The storage member is configured to move between a retracted/closed position and an extended/open position. The bezel provides a resilient member to aid/facilitate installation/attachment of the storage member to the bezel.
US10023123B2 Image display mirror for a vehicle
Provided is an image display mirror that includes a half mirror and an image display apparatus, reduces an influence of a reflected image provided by the half mirror, and is excellent in visibility of an image displayed on the image display apparatus. The image display mirror for a vehicle includes: a circularly polarizing plate arranged attachably and removably; a half mirror; and an image display apparatus in the stated order from a viewer side. In one embodiment, attached and removed states of the circularly polarizing plate are switched when an image is displayed on the image display apparatus and when the image is not displayed thereon, and when the image is displayed, the circularly polarizing plate is arranged between the half mirror and a viewer.
US10023121B1 Rear vision camera switching
Methods and systems are provided for controlling camera images of vehicle cameras. In one example, a camera, a radio system, a processor, and a display are disposed onboard a vehicle. The camera is configured to generate camera images. The radio system is configured to process the camera images. The processor is configured to at least facilitate determining whether a radio system of the vehicle is functioning properly; processing the camera images through the radio system prior to displaying the camera images within the vehicle, if the radio system is functioning properly; and providing instructions for displaying the camera images within the vehicle without processing the camera images through the radio system, if the radio system is not functioning properly. The display is configured to display the camera images in accordance with the instructions provided by the processor.
US10023115B2 Autonomous vehicle handoff alert
A vehicle alert system includes a processor programmed to receive a handoff request indicating a transition of a host vehicle from an autonomous mode of operation to a non-autonomous mode of operation. The processor is further programmed to output a notification signal in response to receiving the handoff request. A vehicle component is configured to deliver an electrical current to a vehicle driver in response to the notification signal.
US10023111B2 Illumination device, in particular in a vehicle
Illumination device, in particular in a vehicle, wherein certain areas in the interior of the vehicle, such as center console, dashboard, and/or side doors, are at least partially covered by real wood elements that are translucent. Illumination units are arranged on the underside of the wood elements and the wood elements can be used to produce differently shaped illuminations with a defined orientation in the vehicle interior. The wood elements have a thickness such that the illumination units are not visible to an occupant when switched off, i.e., not emitting light.
US10023108B2 Vehicle lamp with light module fixing portion
A vehicle lamp includes a housing where a lighting device is disposed, and a fixing unit pressing the lighting device against the housing. The lighting device has a flange, a storage portion protruding from one surface of the flange, and a light-emitting module received in the storage portion opposite to the flange. The storage portion is received in a hole of the housing such that the fixing unit presses the flange against the housing in a peripheral edge of the hole.
US10023106B2 Arrangement for controlling a lighting device of a working vehicle
In accordance with an example embodiment, an arrangement for controlling a lighting device of a working vehicle where the lighting device is directed toward an adjustable operating element of the working vehicle. A control device is connected to the lighting device. The control device is operated to switch the lighting device on according to a detected adjustment of the operating element.
US10023099B2 Structure and method for securing and transporting equipment racks
A shipping apparatus utilizes logistic bars attached laterally across a carrier shipping enclosure such as truck trailer or shipping container. The logistic bars can engage tracks attached to lateral sidewalls of the carrier shipping enclosure. One or more equipment racks are positioned behind one of the lateral logistic bars. Another logistic bar is placed behind the one or more equipment racks. Each of the equipment racks are secured in place by clamping devices positioned along a respective lateral logistic bar to be proximate to a respective corner of the equipment rack. Longitudinal logistic bars are engaged to a pair of the clamping devices that are on opposing lateral sides of the equipment rack. The shipping apparatus provides a rigid structure that is appropriately positioned without damaging components within the equipment rack and preventing swaying during transport of the equipment rack.
US10023098B1 Cargo transport system for a truck
A vehicle includes a truck bed, first docking plate, second docking plate, first bracket, and second bracket. The truck bed has first and second side panels extending upward from a floor panel. The first and second docking plates are secured to opposing internal surfaces of the first and second side panels, respectively. The first and second brackets have upright members secured to the first and second docking plates, respectively, and horizontal members extending from the upright members inward relative to the truck bed.
US10023097B1 Tie down assembly for cargo bed
A tie down assembly for a vehicle cargo bed. The tie down assembly is structured to be coupled to a sidewall of a vehicle cargo bed. The assembly includes a mounting bracket structured to be positionable and securable along the sidewall. The assembly also includes a tie down member rotatably coupled to the mounting bracket and including an indexing member. The mounting bracket has a first indexing cavity structured for receiving the indexing member therein, and a second indexing cavity angularly spaced apart from the first indexing cavity and structured for receiving the indexing member therein. The tie down assembly is structured such that the tie down member is secured in a first angular orientation when the indexing member resides within the first indexing cavity, and in a second angular orientation different from the first angular orientation when the indexing member resides within the second indexing cavity.
US10023096B2 Vehicle roof pillars with receptacles for connectors on an outer side
A vehicle roof structure including a plurality of roof support pillars that include a plurality of receptacles on an outer surface of the pillars. The receptacles are adapted to receive a connector for securing an article to a vehicle either directly or by means of a tie down strap. A spider roof structure or conventional roof structure are disclosed that may include either X-shaped receptacle openings or a T-track slot. Articles may be directly secured to the receptacles or slots on the outer surface of the pillars or may be connected to the roof or side outer walls of the pillar by tie down straps.
US10023094B2 Debris shield adaptable for use with a variety of boats and trailers
Disclosed herein is a debris shield adaptable for use with a boat and a trailer. The debris shield includes a frame assembly, and a canvas. The frame assembly includes a frame and at least one adjustable arm with one end suitable to be connected to either the side portion of the boat that sits above the trailer or the base of the trailer, and another end suitable to be connected to the frame. The adjustable arm is adjustable in length to adapt the frame to at least one of the height of the boat and the width of the trailer base. The canvas includes a substantially rectangular part. The rectangular part has a trailer side, a stern side, a boat side and a bow side. The trailer side is fastenable to the frame. The debris shield is adjustable to at least one of the height of the boat and the width of the trailer.
US10023087B2 Vehicle seat
A vehicle seat (10) comprising a seat cushion frame (72) that configures a seat cushion (70); a seat back frame (14) that configures a seat back (12), the seat back frame (14) being formed in a panel shape and having, on a lower portion thereof on both sides in a seat width direction, coupling portions (46) that are coupled to the seat cushion frame (72); fixing portions (20) that are formed in an upper portion of the seat back frame (14) and fix a headrest (60); and load transmitting portions (40) that are disposed in the seat back frame (14), are each formed in a substantially L-shape opening toward the seat rear side and outward in the seat width direction, and couple together the fixing portions (20) and the coupling portions (46).
US10023081B2 Vehicle seat
A vehicle seat capable of housing a seat main body includes a seat pivot shaft to which the seat main body is connected to be pivotable, and a detachable leg whose upper end is mounted to the seat main body and whose lower end is detachably held onto a leg holding member on a vehicle body floor. When the seat main body moves from a housed state side to a usage state side, a leg guide portion causes a cushion abutting portion to abut a base abutting portion in advance, thereby guiding the detachable leg moving together with the seat main body to pass above a leg movement inhibiting portion which is a portion of a support base.
US10023076B2 Backrest adjuster for a vehicle seat, and vehicle seat
A vehicle seat and a backrest adjuster (1) for a vehicle seat are provided in order to adjust the inclination of a backrest (2.1) of a vehicle seat (2). The backrest adjuster includes a transmission element (5) that is coupled to a fitting (4) and to a pivot bearing (3). A clamping element (11) is mounted in the region of the pivot bearing (3) and in the region of the fitting (4) lying opposite the pivot bearing. In the region between the pivot bearing (3) and the fitting (4), the clamping element (11) is arranged at least in part in the transmission element (5).
US10023072B2 DC-DC converter for vehicle
A method and apparatus for converting dc power from one voltage to another, in a mHEV includes an input filter, a converter circuit, and an output filter. the circuit is implemented with wide band gap devices, and may be a full bridge, half bridge, or push pull circuit. The size is preferably 120 cc, and the output power is preferably at least 500 W, 1 KW or up to 3 KW. The efficiency is preferably at least 80% or 90%, and the converter operates at a frequency of at least between 20 KHz and 2 MHz.
US10023069B2 Battery pack for electric vehicle
A battery pack for an electric motor comprises a base plate, a plurality of rectangular battery modules positioned laterally one next to another, a securing strap provided for each battery module and including an upper portion extending along an upper surface of the corresponding battery module in a fore and aft direction, a front portion extending downward from a front end of the upper portion along a front surface of the corresponding battery module, a rear portion extending downward from a rear end of the upper portion along a rear surface of the corresponding battery module, a front mounting portion formed in a lower end of the front portion and secured to the base plate, a rear mounting portion formed in a lower end of the rear portion and secured to the base plate. A connecting plate extends laterally and is fixedly connected to the securing straps.
US10023066B2 Method and apparatus for determining the status of a battery in a vehicle
A method for determining a status of a vehicle battery includes determining an initial temperature and an initial state of charge of the battery, determining a current threshold value based on the initial temperature and the initial state of charge of the battery, starting the vehicle engine, charging the battery for a predetermined charging period t1, measuring two charging currents, I1 and I2, to the battery at two predetermined points in time during the charging period t1, determining an expected current value at a time t3=t1+t2 based on the measured charging currents, comparing the expected current value with the current threshold value, and determining the battery is faulty if the expected current value is lower than the current threshold value.
US10023057B2 Contactless charger and battery management
An apparatus comprising a contactless battery synchronous power and a battery management system (BSP-BMS) is disclosed. This system includes a battery monitoring unit for monitoring the state of the batteries and a synchronous power unit for controlling the intensity and direction of current during both, charging and discharging processes, including one or several opto-inductive discs for the wireless energy transfer and fast and a lightweight communication scheme. The full system disclosed in this invention is very small in size, lightweight, cost effective and reliable due to its scalable structure, easy parallelization of current control elements and paths, and local and reliable opto-inductive coupling. The invention is aimed at universal, fast and automated charge processes and internal stored energy management for unmanned autonomous vehicles (UAVs) but it can be an effective solution for manned electric vehicles like electric bikes, electric motorcycles or other electric powered vehicles.
US10023056B2 Integrated trailer hitch and jump start system
The present disclosure relates to devices, systems, and methods for jump starting an electric vehicle. In some embodiments, an electric vehicle includes battery charging circuitry electrically connected to a high voltage storage system and a low voltage storage system mounted in the vehicle. The high voltage storage system may be configured to drive a motor for propelling the vehicle. The low voltage storage system may be configured to drive a contactor electrically connected between the high voltage storage system and a drive train of the vehicle. In some implementations, the vehicle may include an electrical connection that is easily accessible and configured to supply power from an external power source to the low voltage system. The electrical connection may be integrated into a standard trailer wiring system.
US10023055B2 Motor control device and motor control method
A rotational speed command output unit receives and outputs a command value of a motor rotational speed inputted from outside. A PWM duty calculator calculates a PWM duty based on the command value and an actual rotational speed of a motor. A maximum speed estimator estimates, based on the actual rotational speed measured, a parameter representing a controlled state of the motor, a current PWM duty and a predetermined upper limit of the PWM duty, a maximum rotational speed of the motor to be reached under PWM control with the upper limit of the PWM duty. The command value inputted from outside is restricted not to exceed the maximum rotational speed. In this way, when a motor is PWM-controlled, abrupt changes in the rotational speed of the motor due to supply voltage fluctuations can be suppressed.
US10023053B2 Battery management system and method
Disclosed is a battery management system, the battery management system including: a module control unit (MCU) which includes a communication module, a capacitor which is connected to the communication module, and a charging module which is connected to the capacitor to charge the capacitor; and a battery control unit (BCU) which transmits a square wave clock signal which enables a communication module of the MCU and controls the MCU, in which when the capacitor is charged with a voltage which is equal to or higher than a predetermined reference voltage, the MCU turns on the communication module.
US10023050B1 Transfer case
A transfer case for a vehicle having a selective four wheel drive mode of operation is provided. The transfer case includes a front shell boltably connected with a rear shell, a front axle output shaft and sprocket, and a main input shaft torsionally connected with a transmission and rear axle of the vehicle. A main sprocket is provided, rotatably mounted on the main input shaft. The sprocket has an axial extension. A chain torsionally connects the main sprocket with the front axle output sprocket. A clutch housing having a splined opening is torsionally connected with the main sprocket extension. A hub is spline connected on the main input shaft. A clutch pack is selectively torsionally connected with the clutch housing and with the hub. A pressure plate is provided to actuate the clutch pack. An electrically powered ball ramp mechanism is provided for axially displacing the pressure plate to torsionally join the main input shaft to the front axle input shaft causing the main sprocket extension to contact the hub.
US10023049B2 Power transfer structure of vehicle
In a transfer structure of a vehicle according to one aspect of the present invention, a drive shaft includes: a first power transfer shaft including a first end coupled to a differential device; a second power transfer shaft including a first end coupled to a second end of the first power transfer shaft through a first universal joint; and a third power transfer shaft including a first end coupled to a second end of the second power transfer shaft through a second universal joint and a second end to which a driving wheel is coupled, and dampers are provided on at least two respective power transfer shafts. Among these dampers, a predetermined damper arranged on the longest power transfer shaft out of the at least two power transfer shafts functions in a frequency region lower than a frequency region in which a remaining damper functions.
US10023047B2 Four-wheel vehicle
A four-wheel vehicle includes an engine at least a portion of which is located farther forward than a seat, a fuel tank located above the engine and forwardly of the seat, a fuel filler including a fuel filler neck and a filler cap, a breather channel connected to the fuel filler, and an outflow prevention valve in the breather channel to prevent outflow of liquid fuel. The outflow prevention valve is located higher in a side view of the vehicle body than both of a lower end of the fuel tank and an upper end of the engine.
US10023041B1 Electric drive system for independent wheel drive
A drive unit includes a housing, a main shaft, an output shaft, an electric motor, a first planetary gear set, and a second planetary gear set. The main shaft is rotatably disposed in the housing, and with the housing cooperatively defines an axis of rotation. The output shaft is disposed at least in part in the housing and is rotatable about the axis. The electric motor is disposed in the housing and has a rotor centered on and rotatable about the axis. The first planetary gear set is centered on the axis and provides a first speed reduction ratio between the rotor and a second planetary gear set. The second planetary gear set provides a second speed reduction ratio between the first planetary gear set and the output shaft.
US10023039B2 Work vehicle with a power-travel drive unit
A work vehicle comprises: a vehicle frame; a driving portion in which a driver seat is provided; an electric motor for driving the vehicle to travel; and a battery for supplying electric power to the electric motor, the battery including a plurality of battery modules accommodated in a single battery pack. Each of the battery modules is formed as a rectangular box whose longitudinal length is different from its lateral length in a planar view, and the battery modules are arranged adjacent to each other with a short side of one of the battery modules opposing a long side of the other of the battery modules. The battery pack is also formed to conform to the contour of the aggregate of the battery modules.
US10023036B2 Vehicle door seal apparatus and method of use
Some embodiments are directed to a seal assembly including a main door seal that extends around a vehicle door interior surface and that is spaced from a door perimeter. A first seal portion extends from an inward end thereof disposed along the main door seal to an outward end thereof disposed along the vehicle door perimeter. The first seal portion forms a barrier vertically above a latch slot, is capable of intercepting substances disposed above and traveling downward toward the latch slot, and facilitates transport of the intercepted substances to the door perimeter. A second seal portion is disposed between the latch slot and the vehicle door perimeter, and extends downwardly from the outward end of the first seal portion. The second seal portion is configured to impede travel toward the vehicle door interior surface of the intercepted substances that have been transported to the vehicle door perimeter.
US10023031B2 Pulley apparatus
A pulley apparatus has: a pulley case (CA) disposed on one side of a vehicle body panel (11a) forming part of the vehicle; a pulley (80) disposed rotatable in the pulley case (CA); and a cable guide disposed in the pulley case (CA), wherein the cable guide is in sliding contact with a cable (18) which is led into an interior of the vehicle through the vehicle body panel (11a), and guides the cable (18) along vehicle body panel (11a) to direct the cable (18) to the pulley (80). As a result, when a load is applied to the cable (18), a case body of the pulley case (40) is pressed against the vehicle body panel (11a), thereby suppressing rattling noise and vibration of the pulley case (CA).
US10023028B2 Switchable variable transmittance window assembly
An autodimming window assembly for a vehicle such as an aircraft includes a UI devoid of movable elements and integrated with a dust cover of the window assembly. A dust cover optionally includes a lightguide configured to deliver light from a light source associated with the assembly and indicia representing an operational characteristic of the UI and articulated to the dust cover.
US10023026B2 Vehicle rear slider window assembly with enhanced rail attachment
A slider window assembly for a vehicle includes at least one fixed window panel and a frame portion attached at the at least one fixed window panel. A movable window panel is movable along upper and lower rails of the frame portion and movable between a closed position and an opened position. At least one of the upper and lower rails includes a recess for receiving adhesive therein and a tapered end region at an end of the recess. The tapered end region includes at least one notch or groove through a wall that at least partially circumscribes the recess, with the notch or groove configured to allow excess adhesive to escape during the adhesive bonding of the at least one of the upper and lower rails to the at least one fixed window panel. The tapered end region has an outer tapered surface opposite the recess.
US10023021B2 Air vent
An air vent with an adjustment insert for adjusting an air stream flowing out through the air vent, can be adjusted by rotating the adjustment insert. A first light guide and a second light guide are provided, with the first light guide being firmly attached to a housing of the air vent and the second light guide being firmly attached to the adjustment insert. The first light guide and the second light guide are rotatable with respect to each other, and the second light guide can be illuminated by the first light guide. A backlightable portion of the adjustment insert can be illuminated by the second light guide.
US10023015B2 Heavy vehicle tire bead
Heavy vehicle tire with two beads (2) contacting rim (3) an outer face (21), radial carcass reinforcement (4) having carcass layer (41) wound within each bead (2) around bead wire (5) having center (O) to form turnup (411), additional circumferential reinforcement (6), in each bead (2), having additional layer (61, 62), additional reinforcement (6) extending radially from radially inner end (E1) to radially outer end (E2) and axially on outerside of axially outermost turnup (411). The orthogonal projection (P1) of radially inner end (E1) of additional circumferential reinforcement (6) onto axially outer face (21) of bead (2) is radially on outside of center (O) of bead wire (5), the orthogonal projection (P2) of radially outer end (E2) of additional circumferential reinforcement (6) onto axially outer face (21) of the bead (2) contacting point (P′2) of rim (3) that is axially on inside of point (C) of last contact of rim (3) when tire (1) is mounted and inflated, and radial distance (d) between end (E1) and end (E2) of additional circumferential reinforcement (6) is at most 20 mm.
US10023014B2 Bicycle tire
Bicycle tire (1) comprising a continuous toothing (5) having a substantially radial generatrix (G) with respect to the rotation axis of the tire in the axial direction (YY′), said toothing (5) being positioned circumferentially on an axially outer face (21) of at least one sidewall (2) and comprising an elastomeric material. A retroreflective strip (6) is positioned circumferentially on the sidewall (2), axially on the outside of the axially outer face (21) of the sidewall (2) and radially on the outside of the toothing (5), a strip support (7) is interposed axially between the retroreflective strip (6) and the axially outer face (21) of the sidewall (2), and an axially outer face (71) of the strip support (7), to which the retroreflective strip (6) is applied, forms an angle (A) of at most equal to 30° with the radial direction (ZZ′) of the tire.
US10023011B2 Tire comprising a tread made up of several elastomeric compounds
A tire the tread of which contains at least three circumferential grooves, having at least three radially superposed layers of elastomeric compounds.A first elastomeric compound constituting the first layer forming the radially outer part of the tread has a maximum value of tan(δ)max, greater than 0.110, a second elastomeric compound constituting the second layer radially on the inside has a tan(δ)max at least 10% lower than the first elastomeric compound, the radially innermost third layer of the tread consists of at least two first parts and of at least three second parts axially, each one in contact with at least one of the at least two first parts, the at least two first parts axially centered on a radial plane passing through one of the at least three circumferential grooves consisting of the second compound and the at least three second parts consisting of a third elastomeric compound having a maximum value of tan(δ), denoted tan(δ)max, at least 10% lower than the second elastomeric compound.
US10023003B2 Damper assembly
A damper assembly for a bicycle wheel assembly may include a first damper configured to be disposed about a hub assembly of the bicycle wheel assembly. The first damper is configured to apply a first damping force against a spoke segment of at least one spoke of a plurality of spokes of the bicycle wheel assembly. The spoke segment is spaced apart from a spoke attachment member.
US10023000B2 Security threads and stripes
The present invention relates to the field of the protection of value documents and value commercial goods against counterfeit and illegal reproduction. In particular, the present invention relates to security threads or stripes comprising a holographic metallic layer; a first transparent substrate; a second transparent substrate; a first hardened coating and a second hardened coating, wherein a first plurality of non-spherical magnetic or magnetizable pigment particles of the first hardened coating are oriented so as to follow a convex curvature and wherein the second plurality of non-spherical magnetic or magnetizable pigment particles of the second hardened coating are oriented so as to follow a concave curvature so as to form a plural rolling bar effect.
US10022997B2 Decoloring apparatus and sorting method for paper discharge in decoloring apparatus
In accordance with one embodiment, a decoloring apparatus comprises a processor, a decoloring section, a shift roller, a paper discharge section and a paper discharge roller. The processor determines whether or not to execute either a decoloring job or a non-decoloring job. The decoloring section decolors an image on paper formed with decolorable coloring agent. The shift roller moves paper for decoloring job or paper for non-decoloring job in a direction orthogonal to a paper discharge direction of the paper on a same plane for a given distance to sort it. The paper discharge section stacks discharged papers. The paper discharge roller discharges the paper sorted by the shift roller to the paper discharge section.
US10022996B2 Infrared sensitive color-forming composition, infrared curable color-forming composition, lithographic printing plate precursor and plate making method
The invention is directed to an infrared sensitive color-forming composition containing a compound having an infrared absorbing skeleton and a thermochromic skeleton in a molecule thereof wherein the infrared absorbing skeleton and the thermochromic skeleton are connected with a covalent bond or an ionic bond and a binder; an infrared curable color-forming composition wherein the infrared sensitive color-forming composition further contains a radical initiator and a polymerizable compound; a lithographic printing plate precursor having an image-recording layer containing the infrared curable color-forming composition on a support; a plate making method including imagewise exposing the lithographic printing plate precursor and conducting on-press development processing by supplying printing ink and dampening water on a printing machine to remove a non-image area; a compound represented by the formula (7) as defined herein; and a compound represented by the formula (8) as defined herein.
US10022995B2 Thermally printable paper article with elastic underlayer
The present invention relates to a thermally printable paper article with an elastomeric underlayer, which imparts improved printing performance.
US10022993B2 Media guides for use in printers and methods for using the same
A media guide is provided for use in printer. Media guide includes main body portion having internal bore configured to be disposed around media spindle and guide member connected to main body portion. Guide member is configured to extend outwardly from main body portion to extended position and to retract toward main body portion to collapsed position. Method for using media guide is also provided. Media guide is disposed on media spindle such that media spindle extends through internal bore of main body portion and is positioned and locked at selected position along length of media spindle. When media roll is disposed on media spindle, guide member is extended to extended position. When media roll is configured to be one of loaded onto or unloaded from media spindle, guide member is retracted to collapsed position.
US10022989B2 Printing apparatus and printing method
A printing apparatus includes: a driving roller configured to drive a recording medium by rotation thereof while being in contact with the recording medium; a discharging head configured to discharge liquid onto a recording medium; a driven rotational member configured to be driven to rotate as a result of transport of the recording medium while being in contact with the recording medium; a rotation position detection unit configured to detect a rotation position of the driven rotational member; and a control unit configured to rotate the driving roller to transport the recording medium and adjust a timing of discharging the liquid from the discharging head in accordance with a detection result of the rotation position detection unit. The control unit adjusts a rotational speed of the driving roller in accordance with a linear pressure applied to the recording medium on the driving roller.
US10022981B2 Ink, ink cartridge, and ink jet recording method
An aqueous ink for ink jet containing a self-dispersible pigment, a compound represented by General Formula (I): where in General Formula (I) each R1 independently represents a hydrogen atom or an alkyl group.
US10022976B2 Controlling an ink flow to a print head
Controlling an ink flow to a print head includes using a diaphragm positioned within a pathway to obstruct the ink flow.
US10022975B2 Liquid cartridge having detection member movable in accordance with deformation of deformable member
A liquid cartridge includes: a cartridge body defining a liquid chamber; a liquid-supply part; a deformable member protruding upward relative to the cartridge body; and a detection member having a detected part. The liquid chamber is configured such that an internal pressure thereof is reduced in accordance with outflow of liquid from the liquid chamber. The deformable member defines an inner space communicating with the liquid chamber, the deformable member being deformable such that a volume of the inner space is reduced in accordance with the reduction in the internal pressure of the liquid chamber. The detected part is movable from a first position to a second position, the detected part at the second position being in contact with the deformable member, the detected part being further movable from the second position to a third position below the second position in accordance with deformation of the deformable member.
US10022972B2 Waste liquid container and attachment
A waste liquid container includes an accommodating case which includes a mounting surface which is an external surface that faces internally in a mounting direction and a first side surface and a second side surface which are outside surfaces extending in a direction intersecting a width direction, a waste liquid introducing portion which is connected to a discharging portion, and a circuit board including a connecting terminal which is electrically connected to a substrate connecting portion. The accommodating case includes a recessed portion which opens on the mounting surface and the first side surface and allows a projecting portion to be inserted therein, when being mounted on the mounting portion, and a notch which opens on the mounting surface and the second side surface vertically below the waste liquid introducing portion. The connecting terminal is disposed inside the recessed portion.
US10022967B2 Liquid jetting apparatus
A liquid jetting apparatus jetting a liquid onto a recording medium conveyed in a first direction includes head units arranged in a second direction orthogonal to the first direction. One head unit includes nozzle chips; one nozzle chip has a nozzle arrangement area wherein nozzles are aligned in a third direction crossing the first and second directions. The nozzle chip is arranged to be shifted relative to another nozzle chip in a direction crossing the first and second directions and different from the third direction. The head unit has a first overlapping portion wherein nozzle arrangement areas of first and second nozzle chips included in the nozzle chips partially overlap with each other in the first direction. The liquid jetting apparatus has a second overlapping portion wherein nozzle arrangement areas of third and fourth nozzle chips included in the head units partially overlap with each other in the first direction.
US10022966B2 Face-down printing apparatus and method
Film-forming apparatuses, systems, and methods are provided. The apparatus can include a substrate positioning system and a printing array that includes an inkjet printing array and/or a thermal printing array. The positioning system can be a gas-bearing plate system. The positioning system can be configured to move a substrate between a first position, away from the printing array, and a second position, above the printing array. The apparatuses, systems, and methods can be used to manufacture organic light emitting devices (OLEDs), for example, flat panel displays.
US10022964B2 Head module and liquid jetting apparatus including the same
There is provided a head module including: a head which has an inlet, a plurality of nozzles, and a plurality of driving elements, and in which the nozzles are aligned in rows in a longitudinal direction of a nozzle surface orthogonal to a attaching/detaching direction of the head module; a plurality of driver ICs; a heat spreader; a flexible substrate; and a rigid substrate. In the attaching/detaching direction, the driver ICs are arranged between the head and the heat spreader; the rigid substrate and the head are arranged side by side in the attaching/detaching direction; the rigid substrate and the heat spreader are arranged side by side in a short direction of the nozzle surface; and the rigid substrate has a thickness along the short direction of the nozzle surface.
US10022958B2 Inkjet head and inkjet recording apparatus
An inkjet head contains a piezoelectric member which alternately includes plural first grooves and plural second grooves respectively constituted by a pair of side surfaces and a bottom surface; a first electrode on at least one of a pair of the side surfaces of each first groove; a second electrode on the side surface to face the first electrode across the piezoelectric member of each second groove; and a driving circuit including plural first drivers for each first electrode and inputting a common first driving waveform to each first electrode, and plural second drivers for each second electrode and inputting a second driving waveform of each second electrode corresponding to print data to each second electrode.
US10022952B1 Mask screen for UV curing
A print system and a method for curing marking material on an object using a mask screen are disclosed. For example, the print system includes a plurality of printheads, a curing light source, a movable member to hold an object, a mask screen and a controller to control movement of the movable member to move the object past the array of printheads, to operate the plurality of printheads to eject the marking material onto the object as the object passes the two-dimensional array of printheads, to control movement of the movable member to catch the mask screen and to operate the curing light source to cure the marking material, wherein the amount of energy that is applied to the object is controlled by the mask screen.
US10022935B2 Air permeable sun shading fabric
An air permeable sun shading fabric for provision of shade while allowing air to permeate the fabric includes a panel that is flexible and comprises a plurality of layers. The plurality of layers comprises an inner layer and an outer layer. Each of the layers has a plurality of openings. The openings are consistently sized and equally spaced, thus defining a band around each of the openings. The opening and a respective one of the bands define a unit. The openings of each of the layers are positioned in rows that are parallel. Each of the rows is offset by one half of the unit from adjacent rows. The layers are mutually coupled, such that each of the pluralities of openings is offset from the pluralities of openings positioned in adjacent layers.
US10022934B2 Heat recoverable tube assembly and adhesive composition for heat recoverable tube assembly
A tube assembly includes glass fiber, a heat-recovered heat recoverable tube surrounding at least a portion of the glass fiber, an adhesive having an adhesive composition comprising a reactive polyethylene and a reactive propylene copolymer. The adhesive adhesively couples the heat-recovered heat recoverable tube to the glass fiber. The adhesive composition includes a reactive polyethylene, such as, a maleic anhydride modified linear low density polyethylene resin, and a reactive propylene copolymer, such as, a maleic anhydride grafted polypropylene copolymer. The adhesive composition is capable of adhering to glass fiber with an axial load of 5 N at 70° C. for a period of at least 60 seconds.
US10022932B2 Container, forming tool, and method for forming a container
A container formed from a blank, a forming, tool and a method of forming a container are disclosed. The container includes features that are formed by a plurality of score lines in a marginal portion of the blank. The container has a bottom wall, a side wall, and a flange extending from the side wall. The flange has a thickness that is greater than a thickness of the blank.
US10022931B2 Arrangement and method for handling a load for isostatic pressure treatment
There is provided an arrangement and a method for handling a load for isostatic pressure treatment in a high-pressure arrangement. The arrangement includes a transportation unit including at least one track for transporting the load into a treatment position for isostatic pressure treatment of the load from a working space outside the high-pressure arrangement. Furthermore, the transportation unit is further arranged for transporting the load from the treatment position to the working space after pressure treatment of the load. The arrangement further includes a partition plane arranged at least partially above the high-pressure arrangement, wherein the working space is provided above the partition plane. The partition plane is arranged to shield the working space from the high-pressure arrangement in the event of a gas leakage of the high-pressure arrangement.
US10022927B2 Method of manufacturing optical waveguide device and laser processing apparatus
An optical waveguide having a plurality of optical paths is formed on a substrate. A reflection mechanism is arranged above the optical waveguide. The reflection mechanism includes mirror components, each of which has an inclined reflective surface, and a mask having a plurality of openings. Laser is irradiated to the mirror components and optical path conversion inclined surfaces are formed in the plurality of optical paths at the same time by the laser reflected on the mirror components.
US10022922B2 Bonded patches with bond line control
A patch may be used to rework a composite structure in the field. The patch is bonded to the structure by a layer of adhesive and includes perforations that allow the escape of air from the adhesive as the patch is compressed against the structure. A spacer may be introduced between the patch and the structure to control the thickness of the adhesive layer.
US10022919B2 Method for impregnating fiber rovings
A die and method for impregnating at least one fiber roving with a polymer resin are disclosed. The die includes an impregnation section. The impregnation section includes an impregnation zone configured to impregnate the roving with the resin. The impregnation zone includes a plurality of contact surfaces. At least one of the plurality of contact surfaces is configured such that a normal force of the roving is less than or equal to a lift force of the resin at an impregnation location on the contact surface during impregnation of the roving with the resin by the contact surface.
US10022917B2 Color switching for three-dimensional printing
By reversing the direction of a first build material fed into an extruder, the first build material can be wholly or partially evacuated from the extruder before a second material is introduced. This approach mitigates transition artifacts and permits faster, more complete changes from one build material to another.
US10022912B2 Additive manufacturing of a unibody vehicle
Methods for manufacturing structures are provided. The methods include manufacturing a shell structure by additive manufacturing methods and sectioning panels with predetermined shapes from the shell structure. The panels are subsequently coupled to shell structure. Devices for performing various steps of the methods are also provided.
US10022911B2 Three-dimensional modeling apparatus, object, and method of manufacturing an object
Provided is a three-dimensional modeling apparatus including a stage, a constraining body, a supply nozzle, an irradiation unit, and a movement mechanism. The constraining body includes a surface including a linear region along a first direction, and is opposed to the stage so that the linear region is the closest to the stage. The supply nozzle supplies a material curable by energy of an energy ray into a slit region between the stage and the linear region. The irradiation unit irradiates the supplied material with the energy ray through the constraining body. The movement mechanism moves the stage relative to the constraining body along a second direction for forming a cured layer of the material for one layer, and moves the constraining body and the stage relative to each other along a stacking direction for stacking the cured layers.
US10022909B2 Systems and methods for manufacturing structural materials
In accordance with embodiments of the present disclosure, a method for forming a structural member may include providing a sheet of structural material and compression molding an in-mold decoration film to a side of the sheet of structural material.In accordance with these and other embodiments of the present disclosure, a method for forming a structural member may include providing a sheet of structural material and adhesively bonding a chassis attachment frame to the sheet of structural material, the chassis attachment frame having one or more attachment features for mechanically coupling the structural member to other one or more other components.In accordance with these and other embodiments of the present disclosure, a method for forming a structural member may include providing a sheet of structural material and molding a chassis attachment frame comprising sheet molding compound to the structural material.
US10022908B2 Resin sheets exhibiting enhanced adhesion to inorganic surfaces
Resin layers and interlayers exhibiting enhanced adhesion to inorganic surfaces, such as glass, are provided. In some cases, the layers and interlayers may comprise at least one adhesion stabilizing agent for improving adhesion to various surfaces, even in the presence of moisture. Such layers and interlayers may be useful, for example, in multiple layer panels, such as, for example, safety glass used in automotive and architectural applications.
US10022905B2 Adiabatic high pressure generation
The invention relates to a system for transforming plastics material preforms into plastics material containers having a plurality of blow molding stations which are arranged on a carrier and in each case comprise a blow mold for expanding plastics material preforms into plastics material containers inside this blow mold by means of a pressurized pneumatic medium which is supplied to the respective blow molding station via a pressure supply device and which is at least partially extracted again from the respective blow molding station after the expansion operation via a pressure extraction device. According to the invention it has an energy conversion device, with the aid of which at least part of the potential energy stored in an energy store can be turned into an increase in the potential energy of a pneumatic medium associated with at least one blow mold, wherein the energy conversion device has an intermediate energy storage device, and at least part of the potential energy extracted from the energy store, and the energy transmitted by the energy conversion device, can be stored in the form of kinetic energy in the intermediate energy storage device.
US10022904B2 Blow molding process and apparatus
In at least some implementations, a blow molding apparatus provides that portions of the parison are engaged by one or more clamping devices disposed on or adjacent to the blow mold parts, and that the blow mold is opened whereby the parison is torn apart between the clamping devices, into two or more pieces of the parison. In other implementations, the clamping devices may be moved relative to the blow mold to tear the parison, or the parison may be torn by a combined movement of the blow mold parts and clamping devices.
US10022901B2 Method for forming a fire-resistant and thermal-resistant glass fiber product, and associated apparatus
A method is provided for forming a glass fiber product, by forming a first mixture including dry melt-resistant filiform glass fibers, a fire-retarding solution, and a thickening agent; forming a second mixture including the first mixture and a binding agent, wherein the first mixture and the binding agent being configured to form an expanding foam; and applying the second mixture to a surface prior to the second mixture forming the expanding foam. A method is also provided for forming a glass fiber product, by adding a thickening agent to a fire-retarding solution to form a first mixture; adding a hardening agent to the first mixture to form a second mixture; and adding dry melt-resistant filiform glass fibers to the second mixture to form a paste mixture. Associated apparatuses are also provided.
US10022900B2 Application device, imprinting apparatus, and method for manufacturing object
Provided is an application device capable of extracting an imprinting material in which impurities are mixed from a container of the application device and supplying new imprinting material to the container of the application device. An application device according to the present disclosure is used to supply an imprinting material to a substrate in an imprinting apparatus that forms a pattern on the imprinting material on the substrate by using a mold. The application device includes a container unit that contains the imprinting material, and an ejecting unit that is provided on the container unit and that ejects the imprinting material contained in the container unit toward the substrate. The application device is detachably attachable to the imprinting apparatus.
US10022899B2 Method for producing a plate-like product using a double-belt press
A double belt press having a first, lower circulating plastic belt and a second, upper circulating plastic belt. The plastic belts have a first, low flexural strength, and a product gap is formed between facing strands of the plastic belts for forming a plate-like product. A first circulating lower steel belt and a second circulating upper steel belt are provided and have a second flexural strength which is high in comparison to the flexural strength of the plastic belts. A forming section is formed between the facing strands of the steel belts, which forms part of the product gap. The first, lower steel belt runs parallel and bears against a rear face of the first plastic belt in the forming section during operation, and the second upper steel belt runs parallel and bears against a rear face of the second plastic belt in the forming section during operation.
US10022898B2 Method for molding fiber-reinforced plastic, and molding device for same
A method for molding fiber-reinforced plastic. A core is formed in a desired shape by accommodating, in a flexible bag, a grain group containing plurality of grains. The core is placed inside a prepreg containing resin and fibers, and the prepreg, in which the core is housed is placed in a molding die and compression molded. When doing so, the grain group contains first and second grains (a,b) that satisfy the equation (1). (1) 1.1≤(Da/Db)≤2.0 In the equation Da is the grain diameter of the grains (a), and Db is the grain diameter of the grain (b). When using a molding die to mold a molded article having a cavity, the above mentioned molding method enables an increase in the internal pressure of the core in order to change the peripheral surface area of the core, without using a pressurized gas and/or pressurized liquid.
US10022890B2 In situ carbonization of a resin to form a carbon-carbon composite
In some examples, the disclosure describes a method including depositing a first layer including a resin and at least one of a carbon fiber or a carbon fiber precursor material on a work surface of a three-dimensional printing system, carbonizing at least the resin of the first layer using a carbonizer attached to the three-dimensional printer to form a first layer of carbon-carbon composite including carbon fibers and carbonized matrix material, depositing an additional layer including a resin and at least one of a carbon fiber or a carbon fiber precursor material of material on the first layer of carbon-carbon composite, and carbonizing at least the resin of the additional layer using the carbonizer to form an additional layer of carbon-carbon composite on the first layer of carbon-carbon composite.
US10022886B2 Rotary cutting die for cutting corrugated board and including a product ejector with integral glue tabs
A rotary cutting die apparatus is provided for die cutting corrugated board. The apparatus comprises a die board having one or more openings formed therein. A product ejector is secured in the one or more openings for engaging a portion of a die cut product and separating the die cut product from the cutting die. Each product ejector comprises compressible material and includes a main body and one or more tabs integral with the main body or operatively associated with the main body, wherein the tabs are secured to the openings or to another portion of the die board.
US10022884B1 Systems and methods for alignment techniques for magnetic cards and devices
Cards may be populated with components and alignment cues. A fully populated card may then be laminated using either of a clear (e.g., transparent) laminate or an obscure (e.g., opaque) laminate. Visual and/or non-visual alignment cues within a card may be utilized to align a trimming and/or singulation device to the card. The card may be singulated and/or trimmed with the aligned singulation and/or trimming device to position one or more components of the card.
US10022882B2 Shaving systems
Replaceable shaving assemblies are disclosed that include a blade unit, an interface element configured to removeably connect the blade unit to a handle, on which the blade unit is pivotably mounted, and an return element disposed between the blade unit and interface element. The return element serves as interface piece, connector and pivot all in one. Shaving systems including such shaving assemblies are also disclosed, as are methods of using such shaving systems.
US10022880B2 Disposable plastic knives with serrated cutting edge
A plastic knife is provided comprising a handle, a blade, and a cutting edge. The blade may include a first surface and an opposite second surface, and integrally formed with and extending longitudinally from the handle. The cutting edge may be formed along one edge of the blade, the cutting edge comprising: (a) a first plurality of teeth integrally connected to and extending from the first surface, each tooth in the first plurality of teeth separated by a first concave groove; and (b) a second plurality of teeth integrally connected to and extending from the second surface, each tooth in the second plurality of teeth separated by a second concave groove. The first plurality of teeth and the second plurality of teeth may be integrally formed together while teeth in the first plurality of teeth and teeth in the second plurality of teeth are offset by a distance.
US10022878B2 Robot
A robot includes a supporting unit that rotatably supports a first passive shaft part, and a first arm fixed to the first passive shaft part, wherein the first arm has an internal space overlapping with the first passive shaft part in a direction orthogonal to a center shaft of the first passive shaft part.
US10022876B2 Joint structure for robot
Provided is a joint structure for a robot which can prevent leakage of a lubricant which is charged to the interior of the joint structure while improving a drip-proof property. The joint structure for the robot includes: a first arm which is hollow; a second arm which is rotatably mounted to the first arm; a power transmission mechanism which is provided adjacent to the outside of the first arm, the power transmission mechanism including a gear and an inner space which houses the gear and is charged with a lubricant; a booster section which increases a pressure in an interior of the first arm to be higher than an outside pressure; and a one-way communication section which allows the interior of the first arm and the inner space to communicate with each other and a gas in the interior of the first arm to flow into the inner space, while preventing the lubricant in the inner space from flowing out to the interior of the first arm.
US10022875B1 Hand tool for attracting and releasing magnetically attractable items
A handheld magnetic tool includes a body having a top arm and a bottom arm connected via a spring, the spring allows the top arm and the bottom arm to open and close; a magnet holder secured to a first end of the top arm; a first magnet secured to the magnet holder; a plate secured to a first end of the bottom arm to close against the first magnet; the first magnet attracts metal items to be secured to a bottom surface of the plate; and opening the top arm from the bottom arm separates the first magnet from the plate, thereby allowing the metal items to release from the plate.
US10022873B2 Apparatuses, systems, and methods for transformable living spaces
The present disclosure provides apparatuses, methods and systems operable to provide transformable living spaces. The system includes a chassis and a configurable unit movably coupled to the chassis for at least one of translation and rotation with respect to the chassis. The system also includes at least one drivetrain assembly movably coupling the configurable unit to the chassis. The system includes at least one actuator coupled to the configurable unit by the at least one drivetrain assembly. The system also includes at least one robotic controller communicatively coupled to the at least one actuator.
US10022870B2 System and method for flexible human-machine collaboration
Methods and systems for enabling human-machine collaborations include a generalizable framework that supports dynamic adaptation and reuse of robotic capability representations and human-machine collaborative behaviors. Specifically, a method of feedback-enabled user-robot collaboration includes obtaining a robot capability that models a robot's functionality for performing task actions, specializing the robot capability with an information kernel that encapsulates task-related parameters associated with the task actions, and providing an instance of the specialized robot capability as a robot capability element that controls the robot's functionality based on the task-related parameters. The method also includes obtaining, based on the robot capability element's user interaction requirements, user interaction capability elements, via which the robot capability element receives user input and provides user feedback, controlling, based on the task-related parameters, the robot's functionality to perform the task actions in collaboration with the user input; and providing the user feedback including task-related information generated by the robot capability element in association with the task actions.
US10022868B2 Inverse kinematic solution for multi-joint link mechanism, and teaching-data creating device using the inverse kinematic solution
This multi-joint link mechanism has a driving joint driven by a driving source and a follower joint driven by the movement of the driving joint. First, an open-loop link mechanism that allows the position and pose of a workpiece to be varied is selected from a multi-joint link mechanism. The amount of movement/rotation of each of the joints constituting the selected open-loop link mechanism is derived. The derived amounts of movement/rotation of each of the joints of the open-loop link mechanism are set as fixed values to derive the amount of movement/rotation of each of the joints of a closed-loop link mechanism composed of non-selected joints and at least some of the joints of the open-loop link mechanism.
US10022862B2 Control-command architecture for a mobile robot using articulated limbs
The present invention applies to a mobile robot which can have a human appearance and sophisticated functions enabling it to execute missions. To enable communications internal to the robot to be optimized and allow for a versatility that is both physical (possible substitution of parts of the robot) and software (replacement of programs to adapt it to new missions), an architecture with three computer levels is provided. The highest level comprises the intelligence of the robot which generates commands which are transmitted by an intermediate computer to low-level cards which control the sensors and actuators. Communication between the intermediate computer and the low-level cards is managed by at least one specific secure communication protocol.
US10022860B2 Rotational driving mechanism in a robot
A rotational driving mechanism for driving a rotary member mounted on a rotatable base member includes: a first link unit that has a first link body and is mounted through a first support part on the base member, the first link unit further having an input part to which an output of the linear motion actuator is inputted at one side of the first link body, and an output part located in the first link body at an opposite side of the input part across the first support part; and a second link unit that has a second link body and is mounted through a second support part on the output part of the first link unit, the second link unit being further mounted through a third support unit on the rotary member or a connecting member joined thereto in such a manner as to be free to rotate.
US10022853B1 Power tools having integral GPS-based locating means
The power tools having integral GPS-based locating means is configured for use as a power tool. The power tools having integral GPS-based locating means is configured for use with the global positioning system (GPS). The power tools having integral GPS-based locating means comprises a power tool, a tracking device, an appropriate authority, and a plurality of messages. The tracking device: 1) is contained within the power tool; and, 2) communicates with the appropriate authority by exchanging a plurality of messages. The tracking device: 1) tracks the GPS location of the power tool; and, 2) provides the GPS coordinates of the power tool to the appropriate authority through the plurality of messages.
US10022846B2 Screwdriver
The present invention provides a screwdriver which includes a shaft, a handle and a speed increasing mechanism, in which the speed increasing mechanism includes a central axle connected to the shaft and provided with a toothed part on its periphery, a first member is disposed in the interior of the handle, at least one gear is connected to the first member, and a geared sleeve is sheathed outside the gear, in which the inner side of the geared sleeve has teeth on corresponding positions, engaging with the gear which is disposed at a side part of the central axle and is engaged with the toothed part of the periphery of the central axle. The present invention also includes a locking mechanism addressing the problem of torque being not high.
US10022843B2 Methods of fabricating a polycrystalline diamond compact
Embodiments of the invention relate to methods of forming polycrystalline diamond compacts (“PDCs”), wherein the PDC includes a polycrystalline diamond (“PCD”) table in which at least one Group VIII metal is at least partially alloyed with phosphorus and/or at least one other alloying element to improve the thermal stability of the PCD table. The disclosed PDCs may be used in a variety of applications, such as rotary drill bits, machining equipment, and other articles and apparatuses.
US10022842B2 Method and systems to control optical transmissivity of a polish pad material
A method and systems for controlling optical transmissivity of a polish pad material are provided. The method and systems may include adjusting control parameters to determine the optical transmissivity of a polish pad material. The control parameters may also include pre-processing controls, casting controls, and/or curing controls. Methods and systems also provided for assembling a polish pad that controls the optical transmissivity of the polish pad. Additionally, a polish pad with a controlled optical transmissivity is provided.
US10022836B2 Polishing pad, polishing apparatus and method for manufacturing polishing pad
The present invention relates to a polishing pad comprising a base sheet containing a restriction layer. The invention also relates to a polishing apparatus and a method for manufacturing a polishing pad.
US10022832B2 Fine-tuning speed application interface
A system, method and computer-readable medium for fine-tuning speed selection for reducing machine chatter. The system includes circuitry configured to determine a predetermined speed of the machine. The circuitry identifies a stability lobe based on the predetermined speed of the machine and selects a first set of fine-tuning speeds from a range of machine speeds corresponding to the determined stability lobe. Further, the circuitry causes the machine to operate at one or more of the first set of fine-tuning speeds.
US10022831B2 Industrial machine provided with foreign matter expulsion mechanism
A foreign-substance discharge mechanism includes: a lubricating-liquid groove provided on a sliding surface of a wedge member and configured to receive a lubricating liquid; and a foreign-substance collector provided to the lubricating-liquid groove and configured to collect foreign substances existing in the lubricating-liquid groove. A first end and a second end of the lubricating-liquid groove are spaced apart from each other in a relative movement direction of the wedge member and the table bed. Disadvantages caused by the presence of the foreign substances between the sliding surfaces can be easily avoided by reliably collecting the foreign substances existing between the sliding surfaces using the lubricating-liquid groove and the foreign-substance collector.
US10022829B2 Apparatus and method for discharge and comminution of a chip
In order to minimize the maintenance effort that accompanies discharge and comminution of a chip, an apparatus for discharge and comminution of a chip has a chip guide and a comminution apparatus, to which the chip guide guides the chip along a chip path. The chip guide has a guide channel that circumferentially surrounds the chip path having a channel inlet and a channel outlet, wherein the guide channel has a maintenance opening in addition to the channel inlet and the channel outlet. Furthermore, a method for discharge and comminution of a chip for this purpose services the guide channel by way of the maintenance opening after discharge and comminution of a chip having a predetermined chip length.
US10022828B2 Zero-point fixture
A zero-point fixture is a means for securing a component in place during machining. The fixture features a base plate that is placed onto a machining surface and a mounting plate to which the component may be attached. The mounting plate and the component are secured to the base plate by operatively engaging a plurality of retention knobs on the mounting plate into a plurality of pressurized clamps on the base plate. A plurality of mounting holes and a plurality of mounting channels allow the component to be mounted in a number of positions and orientations that may be reproduced for subsequent components to be machined. A plurality of risers serves to offset the component from the mounting plate while a plurality of elongated fasteners is inserted into the component to prevent movement of the component during machining.
US10022825B2 Method for restoring, repairing, reinforcing, protecting, insulating and/or cladding a variety of structures
Methods and apparatus are provided for repairing existing structures. A portion of the existing structure is covered with the repair structure. One or more standoffs are coupled to the existing structure to project outwardly away from a surface of the existing structure. One or more cladding panels are coupled to the standoffs by forcing the one or more panels in a direction normal to the surface of the existing structure and into engagement with a standoff connector component of the standoff at a location spaced apart from the existing structure. Curable construction material and/or insulation may be introduced into the space between the cladding panels and the existing structure to provide a repair structure.
US10022824B2 Nickel-iron-phosphorus brazing alloys
Disclosed is a semi-amorphous, ductile brazing foil with a composition consisting essentially of NibalFeaCrbPcSidBeMof with approximately 30 atomic percent≤a≤approximately 38 atomic percent; approximately 10 atomic percent≤b≤approximately 20 atomic percent; approximately 7 atomic percent≤c≤approximately 20 atomic percent; approximately 2 atomic percent≤d≤approximately 4 atomic percent; e≤approximately 2 atomic percent; f≤approximately 5 atomic percent; and the balance being Ni and other impurities; where c+d+e
US10022823B2 Erosion resistant hard composite materials
A hard composite composition may comprise a binder and a polymodal blend of matrix powder. The polymodal blend of matrix powder may have at least one first local maxima at a particle size of about 0.5 nm to about 30 μm, at least one second local maxima at a particle size of about 200 μm to about 10 mm, and at least one local minima between a particle size of about 30 μm to about 200 μm that has a value that is less than the first local maxima.
US10022821B2 Bonding method and bonding device
To provide a wire bonding method and a wire bonding device capable of stably forming a free air ball having a large ball diameter while suppressing oxidation of the free air ball, in addition to supply of an oxidation prevention gas from gas supply means (10) into an insertion portion (32), an oxidation prevention gas is supplied from a gas supply nozzle (40), which is arranged outside the insertion portion (32), so as to cover an inlet of the insertion portion (32). Under a state in which a leading end of a wire (74) is positioned inside the insertion portion (32), and in which a leading end of a capillary (3) is positioned outside the insertion portion (32), spark discharge is generated. With this, a free air ball (75) having a large ball diameter can be formed while suppressing oxidation of the free air ball (75) and stabilizing the free air ball (75).
US10022818B2 Methods and systems for coherent imaging and feedback control for modification of materials
Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light. A feedback controller controls at least one processing parameter of the material modification process based on an interferometry output generated using the imaging light. A method of processing interferograms is provided based on homodyne filtering. A method of generating a record of a material modification process using an interferometry output is provided.
US10022815B2 Drawback valve systems and methods for coolant drawback
A first electrode coolant path is configured to cool a first welding electrode by liquid coolant flowing from a supply path through the first electrode coolant path to a return path. A second electrode coolant path is configured to cool a second welding electrode by liquid coolant flowing from the supply path through the second electrode coolant path to the return path. Three or more valves are configured to stop or reduce liquid coolant flow through the first or second electrode coolant path and configured to stop or reduce liquid coolant backflow from the return path when the first or second welding electrode is at least partially detached. At least one valve is coupled in the first or second electrode coolant path. A drawback apparatus generates a suction force to draw liquid coolant away from a gap formed when the first or second welding electrode is at least partially detached.
US10022814B2 Method and welding apparatus for the determination of the strength of the welding current to be used in the welding of container bodies
For the determination of the welding current to be used for the resistance welding of the overlap seam of container bodies, welding with a test body is carried out with a changing strength of welding current which in the test body produces a varying welding of the seam. The current strength varies from welding of this seam with a too high temperature to welding with a too low temperature. Along with this the welding current strength used in the welding is determined so that it is further determined at which point of the seam the welding has been accomplished and with what strength of welding current. By means of a mechanical and/or optical investigation of the welded seam it can then be easily determined where the seam has been correctly welded for the series production of container bodies from the same sheet material as the test bodies. When such a point or such a region of the seam is known the welding current used in the test welding can be taken as the welding current for serial production.
US10022813B2 Short arc welding system
A system for controlling a weld-current in an arc welding apparatus for short arc welding comprising a current regulator included in a voltage feedback loop from a power supply to a welding electrode and a ramp generator arranged to provide current ramps during a short circuit phase at said welding electrode.
US10022812B2 Methods for the electroerosion machining of high-performance metal alloys
A method of machining a work-piece formed of titanium-based material, using a machining apparatus, is described. The method includes the steps of providing an electrically-conductive electrode contained within a spindle assembly, in a pre-selected distance and position relative to the titanium-based work-piece; while electrically powering the electrode and the work-piece with a power supply. In the process, fluid electrolyte is circulated through at least two pathways in the machining apparatus—an internal conduit within the spindle assembly; and an external conduit. The charged electrode is moved relative to the work-piece in a plunging motion, to remove material from the work-piece at a relatively high rate, using a high-speed electro-erosion (HSEE) process.
US10022806B2 Damping elements for tool chucking systems
Damping elements for tool chucking systems for damping vibrations and shocks that occur during machining in the case of force-fitting clamping of tools in a tool receptacle or on the tool itself. At least one damping element consisting of a shape memory alloy having a mechanical effect is provided in a tool chucking system or on the tool itself, such that the damping element provided in the chucked state in the force flow of the chucked elements is present in a reversible and hysteresis-dependent state by way of a mechanical force action and the associated crystalline conversion via the pretensioning of said damping element and leads to dissipation of mechanical energy. The mechanical energy to be damped is a cyclical vibration or represents a non-cyclical overload which is transmitted in the form of shocks.
US10022803B2 Cutting insert having constant-width wiper surface and cutting tool
An indexable cutting insert has opposing first and second polygonal end surfaces (2, 3) connected by a peripheral side surface (4). Sets of cutting edges (5) are formed at the intersection of each end surface with the peripheral side surface. Each set of cutting edges includes a corner cutting edge (6), first and second cutting edges (7), (8) on opposite sides of the corner cutting edge (6) and a wiper edge (9) formed between the second cutting edge (8) and the corner cutting edge (6). The peripheral side surface (14) includes a wiper-edge side surface (14) having constant width as it extends between the first and second end surfaces (2, 3). A boundary of the wiper-edge side surface (14) with a second side surface below the second cutting edge (8) is inclined with respect to a direction perpendicular to the first end surface.
US10022800B2 Simultaneous turning device for fabrication of eyeglass lenses
A turning device has two turning stations, each with a rotatable work piece spindle to hold a lens blank and each with a turning tool for the machining of a lens blank. A fabrication mechanism for the manufacturing of eyeglass lenses from lens blanks includes a milling device and the turning device, wherein the milling device has at least one milling station with a work piece holder to hold a lens blank and a milling tool for the machining of the lens blank. A loading device is configured to remove lens blanks from the milling device and load them into the turning device. A method for operating such a fabrication mechanism includes simultaneous machining of a third lens blank with the milling tool and a first and a second lens blank with the turning tools.
US10022792B2 Process of dough forming of polymer-metal blend suitable for shape forming
Processing of polymer-metal blend composition involving viscosity control under ambient conditions suitable for shape forming and homogeneous green body preparation. The advancement involves effective controlling of the rate of settling of the metal particles in polymer-metal blend under ambient conditions to generate a cost effective and simple process for producing shape formable dough. Advantageously, the present invention provides a rapid, energy saving process involving minimum material loss and utilizing non hazardous solvent system such as water.
US10022791B2 Method for synthesizing self-assembling nanoparticles
Embodiments disclosed herein relate to a method for synthesizing self-assembling nanoparticles with defined plasmon resonances. More particularly, certain embodiments disclosed herein relate to an improved method for synthesizing self-assembling gold nanoparticles by dialyzing samples during the self-assembly process or in presence of a surface to reduce certain subpopulations.
US10022786B2 Ultrasonic grain refining
A molten metal processing device including an assembly mounted on the casting wheel, including at least one vibrational energy source which supplies vibrational energy to molten metal cast in the casting wheel while the molten metal in the casting wheel is cooled, and a support device holding the vibrational energy source. An associated method for forming a metal product which provides molten metal into a containment structure included as a part of a casting mill, cools the molten metal in the containment structure, and couples vibrational energy into the molten metal in the containment structure.
US10022785B2 Method of continuous casting
A method of controlling the amount of hydrogen in steel for consistent heat transfer in continuous casting by adding a hydrocarbon to the molten metal. A heat of molten steel is formed in a ladle metallurgy furnace adapted for use in continuous casting. Then, a hydrocarbon is added to the molten metal in the ladle metallurgy furnace in an amount sufficient to increase hydrogen levels in the molten steel for casting. And finally, the molten steel with a desired level of hydrogen is delivered to a caster to continuously cast a steel product.
US10022779B2 Mechanically tuned rapid discharge forming of metallic glasses
A mechanically tuned rapid capacitive discharge forming apparatus and methods that utilize compliant and shock absorbing components in electrode assemblies in order to accommodate the stresses and strains of the thermally-expanding feedstock and maintain continuous electrical contact between the electrodes and the feedstock throughout the duration of the electrical discharge.
US10022776B2 Panel forming method and apparatus
Embodiments of the present invention provide a method of forming a feature line in a motor vehicle body panel. The method may comprise: in a first press operation, forming the panel into a first shapeform, the first shapeform having at least one feature line having a first radius of curvature; and in a second press operation, forming the panel into a second shapeform in which the at least one feature line has a second radius of curvature lower than the first.
US10022774B2 Embossing method and apparatus
A method of embossing a crown cap comprises the steps of: detecting a pre-printed drawing on the bottom of the crown cap, varying the angular positioning of the crown cap so as to position the drawing according to a preset positioning, and impressing a raised/recessed pictogram on the bottom of the crown cap. The pre-printed drawing and the embossed pictogram will have a desired reciprocal position.
US10022773B2 Aluminum sheet with enhanced formability and an aluminum container made from aluminum sheet
In some embodiments of present disclosure, a method includes: obtaining an aluminum sheet comprising a 3xxx or a 5xxx alloy having a tensile yield strength as measured in the longitudinal direction of 27-33 ksi and an ultimate tensile strength; wherein the ultimate tensile strength minus the tensile yield strength is less than 3.30 ksi (UTS-TYS<3.30 ksi); and forming a container having a dome from the aluminum sheet.
US10022770B2 Method and tool for precision cutting
A method and tool for producing workpieces with small corner radii in relation to the cutting thickness and with greatly reduced draw-in by precision cutting in a precision cutting tool includes clamping the workpieces between two tool parts consisting of a respective top and bottom cutting dies and of a top and a bottom cutting punch. The workpiece is machined in a one-stage arrangement in at least two successive cutting sequences in different cutting directions with the following partial steps: (A) cutting out a semifinished product, matched to the workpiece geometry, in a first cutting operation in a vertical working direction with slight draw-in, and (B) finish cutting of the semifinished product, produced in step (A), in at least one further cutting operation in a working direction opposed to step (A), wherein the draw-in of partial step (A) is filled again at least in the corner region.
US10022760B2 Cut-to-length steel coil processing line with stretcher leveler and temper mill
A cut-to-length steel coil processing line has an un-coiling reel, a temper mill, a stretcher leveler, a shearer, and a stacking apparatus arranged to sequentially process a continuous length of sheet metal. The line may be configured such that the continuous length of the sheet metal is directed from the uncoiling reel through the temper mill to the stacking apparatus without processing through the stretcher leveler when a determined thickness of the continuous length of sheet metal is at or below a selected measurement criteria. In the alternative, the line may be configured such that the continuous length of the sheet metal is directed from the uncoiling reel through the stretcher leveler to the stacking apparatus without processing through the temper mill when the determined thickness of the continuous length of sheet metal is greater than the selected measurement criteria.
US10022755B2 System for pipe treatment
A pipe treatment system for a supply unit is provided. The pipe treatment system comprises a fresh water inlet pipe, a tap for fresh water, a controllable tap valve, and a control device for the pipe treatment control system. The controllable tap valve is arranged between the fresh water inlet pipe and the tap for fresh water. The control device for the pipe treatment control system is connected to the controllable tap valve so as to place the controllable tap valve in a pipe treatment state when there is a pipe treatment signal at the control device, so as to provide a more reliable pipe treatment system, for example for disinfection or descaling.
US10022747B2 Fabrication assembly and methods for fabricating composite mirror objects
A fabrication assembly comprises an apparatus that receives a composite substrate and a glass substrate having a surface with a release coating layer. A resin layer is deposited between the composite and glass substrates such that a first portion of the resin layer is positioned adjacent to a surface of the composite substrate and a second portion of the resin layer is positioned adjacent to the surface with the release coating layer to prevent aperture(s) from forming. A curing of the resin layer is conducted using electromagnetic radiation. A post-processing chamber receives the resin layer positioned between the composite substrate and the glass substrate and conducts another curing of the resin layer. The resin layer and the composite substrate are released from the glass substrate. Another deposition apparatus receives the resin layer and the composite substrate. A metallic coating is deposited to form a composite mirror object.
US10022746B2 Apparatus and method for treating a substrate
In apparatus and method according to example embodiments of the inventive concept, a substrate may be treated using two or more treatment solutions. The substrate treating apparatus may include a treatment vessel providing a treatment space, a substrate supporting unit provided in the treatment vessel to support a substrate, and a solution supplying unit supplying a treatment solution on the substrate supported by the substrate supporting unit. The solution supplying unit may include an etching solution supplying nozzle supplying an etching solution on an edge region of the substrate supported by the substrate supporting unit and an etch prevention solution (EPS) supplying nozzle supplying an etch prevention solution on a center region of the substrate supported by the substrate supporting unit. Accordingly, it is possible to prevent the center region of the substrate from being dried.
US10022743B2 Coating film production method, coating film production apparatus, coating film, nonaqueous secondary battery electrode plate, and mobile body
When a coating material is rolled between rolls to generate a a coating film, and the coating film is transferred onto the coating object, at first, a residual coating material layer based on a residual coating material is formed on each of the surfaces of the rolls, and supply of the coating material and transfer of the coating film are carried out in a state where the residual coating material layer is retained on each of the surfaces of the rolls, thereby suppressing abrasions between the rolls and the coating material.
US10022739B2 Fluid dispensing apparatus and method
A fluid dispenser for containing and dispensing metered amounts of fluid that includes a reservoir for containing fluid and a chamber positioned substantially within the reservoir for containing a quantity of the fluid. The fluid dispenser additionally includes a piston that is moveable within the chamber to draw fluid into the chamber when the piston is moved in a first direction with respect to the chamber, and to discharge fluid from the chamber when the piston is moved in a second direction opposite the first direction. Further, the fluid dispenser includes a user-manipulatable control coupled to the piston and rotatable about an axis to select one of at least two different metered quantities of fluid to be dispensed. The user-manipulatable control is further movable to move the piston relative to the chamber along the axis to selectively dispense the selected metered quantity of fluid.
US10022729B2 Method for continuously clarifying a flowable suspension with a centrifuge, which involves a time-limited solid-matter discharge by opening and closing solid-matter discharge openings of the centrifuge to discharge the solid matter
A method is provided for continuously clarifying a flowable suspension with a discontinuously solid-discharging—self-discharging—separator, which has a rotatable drum with a vertical axis of rotation, a feed for the suspension to be clarified and at least one liquid discharge for continuously discharging at least one clarified liquid phase, and discontinuously openable solid-discharge openings for discontinuously discharging the solid phase. The method involves a) measuring one or more of the suspension parameters mass, mass of solid substance in the suspension, mass flow, temperature, density, cumulative density; and b) initiating a time-limited discharge of solid substance as a result of a repeated determination on the basis of step a) in the event of or after the exceeding of a limit value.
US10022716B2 Method for producing ionic polymer membrane
To provide a simple method whereby an ionic polymer membrane having a high ion exchange capacity and a low water uptake can be produced by converting a —SO2F group in a polymer to a pendant group having multiple ion exchange groups, while preventing a cross-linking reaction.At the time of obtaining an ionic polymer membrane by converting —SO2F (group (1)) in a polymer sequentially to —SO2NZ1Z2 (group (2)), —SO2N−(Mα+)SO2(CF2)2SO2F (group (3)), —SO2N−(H+)SO2(CF2)2SO2F (group (4)) and —SO2N−(Mβ+)SO2(CF2)2SO3−Mβ+ (group (5)), the polymer is formed into a polymer membrane in the state of any one of the groups (1) to (4), and the polymer membrane is thermally treated in the state of group (4). Here, Z1 and Z2 are hydrogen atoms, etc., Mα+ is a monovalent cation, and Mβ+ is a hydrogen ion or a monovalent cation.
US10022714B2 Catalyst and method for producing maleic anhydride
The invention relates to a catalyst molded body for preparing maleic anhydride by gas-phase oxidation of a hydrocarbon having at least four carbon atoms using a catalytically active composition containing vanadium, phosphorus and oxygen. The shaped catalyst body has an essentially cylindrical body having a longitudinal axis. The cylindrical body has at least two parallel internal holes which are essentially parallel to the cylinder axis of the body and go right through the body. The catalyst molded body has a large outer surface area, a lower pressure loss and sufficient mechanical stability.
US10022710B2 Method of forming a catalyst with an ion-modified binder
An alkylation catalyst having a zeolite catalyst component and a binder component providing mechanical support for the zeolite catalyst component is disclosed. The binder component is an ion-modified binder that can include metal ions selected from the group consisting of Co, Mn, Ti, Zr, V, Nb, K, Cs, Ga, B, P, Rb, Ag, Na, Cu, Mg, Fe, Mo, Ce, and combinations thereof. The metal ions reduce the number of acid sites on the zeolite catalyst component. The metal ions can range from 0.1 to 50 wt % based on the total weight of the ion-modified binder. Optionally, the ion-modified binder is present in amounts ranging from 1 to 80 wt % based on the total weight of the catalyst.
US10022707B2 Sulfur-tolerant CO shift conversion catalyst and preparation method thereof
The present invention discloses a sulfur tolerant carbon monoxide shift conversion catalyst, prepared by the following materials: magnesium source, aluminum source, oxide flux, crystal growth agent, rare earth additive, CoO, MoO3 and an acidic aqueous solution. A preparation method of the catalyst is provided, comprising the steps of: S1, Adding an aqueous acidic solution and a specific amount of rare earth additive to a specific amount of magnesium source, aluminum source, oxide flux and crystal growth agent, followed by kneading to produce a mixture; S2, Extruding the mixture to obtain an extruded strip product; S3, Drying the extruded strip product to give a semi-finished product; S4, Calcining the semi-finished product to obtain a catalyst carrier; S5, Impregnating the catalyst carrier with the active components CoO and MoO3 by an incipient-wetness impregnation method to obtain an impregnated product; and S6, Calcining the impregnated product to obtain the catalyst. The oxide flux and crystal growth agent can participate in a solid phase reaction between the magnesium source and aluminum source to form spinel structure, thereby improving the mechanical strength and stability of the spinel. The nano-sized active component can effectively improve the dispersion of the active component, and improve the catalytic activity of the granular boundary of the active component.
US10022703B2 Method of preparation of nanoparticular metal oxide catalysts
The disclosure concerns an improved method of preparation of nanoparticular vanadium oxide/anatase titania catalysts having a narrow particle size distribution. In particular, the disclosure concerns preparation of nanoparticular vanadium oxide/anatase titania catalyst precursors comprising combustible crystallization seeds upon which the catalyst metal oxide is coprecipitated with the carrier metal oxide, which crystallization seeds are removed by combustion in a final calcining step.
US10022701B2 Coating methods using organosilica materials and uses thereof
Methods for coating a substrate with a coating including an adsorbent material and a binder comprising an organosilica material which is a polymer comprising independent units of Formula [Z3Z4SiCH2]3 (I), wherein each Z3 represents a hydroxyl group, a C1-C4 alkoxy group or an oxygen atom bonded to a silicon atom of another unit or an active site on the substrate and each Z4 represents a hydroxyl group, a C1-C4 alkoxy group, a C1-C4 alkyl group, an oxygen atom bonded to a silicon atom of another unit or an active site on the substrate are provided. Methods of gas separation are also provided.
US10022699B2 Furnace coil fins
The present invention provides low profile, thick (“stubby”) longitudinal fins having a cross section which is a parallelogram, trapezoid or a triangle extending from 10% to 100% of a coil pass and comprising from 3 to 45 weight % of a coil in a radiant section of a furnace for thermally cracking one or more of paraffins and naphtha. The fins provide an additional surface through which heat may be transferred to the coil making the coil more efficient reducing greenhouse emissions.
US10022698B2 Ethylene oligomerization process
An ethylene oligomerization system is useful for creating 1-butene from ethylene in the presence of an ethylene oligomerization catalyst. The ethylene oligomerization system includes an internal baffle single pass reactor, a separation system and an external motion driver. The external motion driver is operable to induce unsteadiness in the flow of the process fluid contained in the internal baffle single pass reactor by transferring motion into the process fluid. An ethylene oligomerization process is useful for creating a refined 1-butene product from ethylene using the ethylene oligomerization system.
US10022694B2 Calibration device for a thermal cycler
The present invention relates to a calibration device and method for use in calibrating a thermal cycler having a reaction zone (140), an excitation light source (120) and an optical detector (110), the device comprising one or more ambient condition sensors (210″, 230″), each adapted to sense an ambient condition at a respective position within said reaction zone, one or more emission light generators (220″) adapted to be in optical communication with the optical detector (110), and control circuitry coupled to the one or more ambient condition sensors and to the one or more emission light generators, wherein the control circuitry is configured to alter the emission light generated by the one or more emission light generators based on the ambient condition sensed by the one or more ambient condition sensors.
US10022692B2 Fischer-Tropsch catalyst activation procedure
A Fischer-Tropsch catalyst activation system including separation apparatus configured for separating a product gas comprising primarily hydrogen from a gas stream comprising hydrogen, an activation reactor fluidly connected with the separation apparatus via an activation gas inlet line whereby the product gas may be introduced into the activation reactor, and a circulation loop fluidly connecting a gas outlet of the activation reactor with the activation gas inlet line or with another gas inlet of the activation reactor and fluidly connecting the activation reactor with one or more apparatus configured for removal of H2O. A method of activating a Fischer-Tropsch catalyst is also provided.
US10022691B2 Wetting and anti-foaming agent
A wetting agent according to Formula (I): wherein R1 is selected from a branched alkyl group or linear alkyl group or a cycloaliphatic group or an aromatic group, each having 6 to 15 carbon atoms; R2 is selected from hydrogen, methyl, or ethyl; R3 is selected from hydrogen, methyl, or ethyl; R4 is selected from hydrogen, methyl, or ethyl; R5 is selected from methyl or ethyl; x ranges from 0 to 5; y ranges from 0 to 10; z ranges from 1 to 10; with the proviso that when x ranges from 1 to 5, R2 is different from R3; and with the proviso that when x=0, R3 is different from R4. The wetting agent also imparts anti-foam properties to aqueous solutions while reducing surface tension.
US10022686B2 Utilizing wet fracturing sand for hydraulic fracturing operations
A system and a method that utilizes wet proppants when creating fracturing fluid by receiving wet fracturing sand at a surge tank, vibrating the wet fracturing sand located within the surge tank, liquefying the wet fracturing sand within the surge tank based on the vibration, and metering the liquefied wet fracturing sand from the surge tank to a blending tub.
US10022682B2 Super-micro bubble generator
To generate homogenized super-micro bubbles of nano-scale in a simple structure and at a low cost, a super-micro bubble generator has a cylindrical casing provided with an opening for the introduction of a liquid at one end and an outlet for delivery of the liquid at the other end, and the cylindrical casing includes: a flow speed increasing part for increasing the flow speed of the liquid introduced from the introduction opening; a gas suction part for drawing gas from the outside into the casing, wherein the pressure is decreased by a liquid flow whose flow speed is increased in the flow speed increasing part; and a super-micro bubble-containing liquid producing part for shearing, by the liquid flow whose flow speed is increased in the flow speed increasing part, the gas that is sucked by the gas suction part and generating a liquid including super-micro bubbles, in this order, from the introduction opening to the delivery opening.
US10022681B2 Pressurized liquid stream with dissolved gas
A system and method of injecting a gas enriched and/or emulsified first liquid into a second liquid is disclosed. The injection can cause generation of a high density of bubbles having a mean diameter of a selected size. The mean diameter of the bubbles can be selected and varied based on the characteristics of the injection system.
US10022674B2 Filter device
A filter device including a stationary head piece and a movable end piece and a pack of adjacent elements including a recess plate, wherein the pack is arranged between the stationary head piece and the movable end piece, wherein the recess plate includes a base element including a recess forming a filter chamber between the adjacent elements, wherein the filter device includes a filter membrane between the adjacent elements, wherein the filter membrane retains a solid content of a suspension as a filter cake and allows a remaining liquid fraction of the suspension to pass as a filtrate, wherein the recess plate includes a fluid pipe discharging the filtrate, which fluid pipe runs along a narrow edge of the base element, wherein the recess plate includes a fluid duct that connects the fluid pipe to the filter chamber.
US10022673B2 Manifolds for use in conducting dialysis
The present application discloses novel systems for conducting the filtration of blood using manifolds. The manifolds integrate various sensors and have fluid pathways formed therein to direct fluids from various sources through the requisite blood filtration or ultrafiltration system steps.
US10022671B2 Exhaust gas purification device
An exhaust gas purification device includes: a wall-flow-structured base material having input-side cells, output-side cells, and a porous partition wall; and a catalyst layer formed inside the partition wall contacting the input-side cells or the output-side cells. The catalyst layer is formed in a region extending from the surface of the partition wall and covering at least 90% of the thickness of the partition wall, and is held by the surfaces of the inside pores of the partition wall in the region. Further, the average filling ratios A, B, and C of the catalyst layer held by pores in respective pore size ranges satisfy a specific relationship.
US10022670B2 Vehicle air supply system
A vehicle air supply system, in particular in automotive vehicles. The essence of the air supply system according to the vehicle air supply system is that inside the system there is a photocatalyst between at least one air intake (1,2) and at least one supply port (5). The photocatalyst may be deposited on inner surfaces of at least one element selected from the group including vehicle's ventilation/air conditioning system (3), inlet ducts (4), supply ports (5), dampers (7) and filters (9). Preferably, the photocatalyst is given in the form of a bypass (6) or an insert (10) or an adapter (8).
US10022669B2 Process and apparatus for eliminating NOX and N2O
A process for removing N2O and NOx from offgases by catalytic decomposition of N2O by means of iron-containing zeolite catalysts and catalytic reduction of the NOx by means of reducing agents, the deNOx stage connected downstream of the deN2O stage being operated at inlet temperatures of T<=400° C., and the inlet gas for the deN2O stage comprising water and having a selected N2O/NOx ratio, and the operating parameters of temperature, pressure and space velocity of the deN2O stage being selected so as to result in an N2O degradation of 80 to 98%. Under these conditions, a degree of NOx oxidation of 30-70% is established at the outlet of the deN2O stage, which is defined as the ratio of the molar amounts of NO2 to the total molar amount of NOx. The result of this is that the downstream deNOx stage can be operated under optimal conditions. Also provided is an apparatus for carrying out the process.
US10022668B2 Self-regenerative integrated device for synergetic oxidation of low-concentration gas and ventilation gas in coal mine
Disclosed is a self-regenerative integrated device for the synergetic oxidation of low-concentration gas and ventilation gas in a coal mine. The integrated device comprises a metal shell (5). A honeycomb ceramic oxidation bed (13) is arranged within the metal shell (5) and divided into a regenerative section (40) and an oxidation section (41) by a heat exchange chamber (14). A first cavity between the regenerative section (40) and the inner wall of the metal shell (5) is divided into a first inlet chamber (6) and an exhaust chamber (8) by an inlet partition plate (7), a second cavity between the oxidation section (41) and the inner wall of the metal shell (5) is divided into a second inlet chamber (22) and a mixing chamber (20) by a partition plate (21) for averaging gas, and a plurality of gas nozzles (28) are provided on the partition plate (21) for averaging gas. An internal heat exchanger (35) is arranged within the heat exchange chamber (14), and a heat exchanger inlet (16) and a heat exchanger outlet (15) of the internal heat exchanger (35) are respectively connected with a boiler drum (18). The first inlet chamber (6) is connected with an inlet (1) of the ventilation gas through a proportional control valve (38), the second inlet chamber (22) is connected with an inlet (31) for extracting the low-concentration gas through a proportional mixer (33), and the proportional control valve (38) is connected with the proportional mixer (33) through a connecting pipeline (36). The two ends of an inlet preheating pipe (9) on the honeycomb ceramic oxidation bed (13) are respectively communicated with the first inlet chamber (6) and the mixing chamber (20).
US10022667B2 Systems and methods for increasing nitrogen dioxide fraction in exhaust gas at low temperature
An aftertreatment system includes a first oxidation catalyst, a second oxidation catalyst, and a turbocharger. The first oxidation catalyst is upstream of the turbocharger and includes a first oxidation catalyst formulation. The second oxidation catalyst is downstream of the turbocharger and includes a second oxidation catalyst formulation different than the first oxidation catalyst formulation. The second oxidation catalyst formulation is configured to promote conversion of nitric oxide (NO) to nitrogen dioxide (NO2).
US10022666B2 Kiln baghouse with dynamically selectable and reconfigurable polishing and non-polishing operations
The present invention is an apparatus and method having dynamically reconfigurable air flow paths for supporting polishing and non-polishing operations. The invention includes a first baghouse section and a second baghouse section coupled to the first baghouse section via conduit. A set of valves is disposed along the conduit to direct air flow through the baghouse apparatus. A controller configures the baghouse apparatus by actuating at least one valve in the set of valves. The controller automatically configures the baghouse apparatus in either a polishing operation or a non-polishing operation based on a predetermined criteria.
US10022664B2 Canister for vehicle having auxiliary canister
Disclosed is a canister for a vehicle having an auxiliary canister, which includes: a main canister that has an inlet and an outlet formed therein, an evaporation gas being introduced into the main canister through the inlet from a fuel tank and the evaporation gas introduced through the inlet being discharged through the outlet to the intake side of an engine when the engine is driven, and has a trapping member therein; and an auxiliary canister that is installed to communicate with the main canister to allow external air to be introduced into the main canister or to allow the evaporation gas to flow when the engine is turned off, and has a second trapping member therein, wherein the auxiliary canister includes the second trapping member therein, which has a plurality of pores in the form of a honeycomb.
US10022663B2 Oxygen sensor protection
An air separation system includes an air separation module configured to receive feed air and separate the feed air into nitrogen-enriched air and oxygen-enriched air, a nitrogen-enriched air line for transporting the nitrogen-enriched air from the air separation module to a fuel tank for inerting, an oxygen sensing line connected to the nitrogen-enriched air line, a gas adsorption filter located in the oxygen sensing line, and an oxygen sensor downstream of the gas adsorption filter in the oxygen sensing line.
US10022658B2 Water filter system
A water filter system includes a removable filter unit having a body portion including a proximal end and a distal end. The proximal end is adapted to be inserted into a filter head assembly. A laterally extending key member is disposed on the body portion and adapted to engage a key slot in the filter head assembly. An engagement protrusion extends from the proximal end. The engagement protrusion includes a first portion that has a first radius of curvature and a second portion opposing the first portion that includes a second radius of curvature that is larger than the first radius of curvature.
US10022657B2 Filter media suitable for hydraulic applications
Filter media, including those suitable for hydraulic applications, and related components, systems, and methods associated therewith are provided. The filter media described herein may include two or more layers, at least one of the layers having a relatively high percentage of microglass fibers. Additionally, the filter media may be designed such that the ratio of average fiber diameters between two layers is relatively small, which can lead to a relatively low resistance ratio between the layers. The filter media has desirable properties including high dirt holding capacity with low basis weight and a low resistance to fluid flow. The media may be incorporated into a variety of filter element products including hydraulic filters.
US10022653B2 Water catchment and soil treatment system
A water catchment and lawn edging system includes a cap, a channeled drain fixture, and at least one base clip. The base clip, which connects the system to the ground surface, is connected to a bottom end of the channeled drain fixture. Depending upon the length or the profile of the channeled drain fixture, the system can utilize a single base clip or a plurality of base clips to properly support the system. The cap is continuously connected along the channeled drain fixture from a top end of the channeled drain fixture. The cap may include a plurality of drain openings to provide additional drainage for the system. Collectively, the cap, the channeled drain fixture, and the base clip function as a water catchment and lawn edging system so that surface and ground water can be drained and filtered away from a collecting area and discharged into an outfall.
US10022652B2 Solution treatment apparatus and solution treatment method
A solution treatment apparatus connected to a supply nozzle that supplies a treatment solution to a substrate, includes: a supply pipeline connecting a treatment solution storage container and the supply nozzle; a filter apparatus provided in the supply pipeline; a pump on a secondary side of the filter apparatus; a circulation pipeline connecting a discharge side of the pump and an intake side of the filter apparatus; a supply control valve provided in the supply pipeline on a secondary side of the pump; a circulation control valve provided in the circulation pipeline; and a control unit, wherein the control unit opens the circulation control valve and drives the pump when supply of the treatment solution from the supply nozzle to the substrate is stopped by closing the supply control valve, to thereby circulate the treatment solution between the supply pipeline having the filter apparatus and the circulation pipeline.
US10022649B2 System, and associated method, for recovering water from air
A system for recovering water from air includes a base plate having an upper surface having a substantially non-reflective surface to absorb heat energy from the sun. A column is positioned on the base plate and has at least one wall through which heat energy from the sun may pass to the base plate to heat the base plate, and the base plate heats air in the column. An upper thermally conductive plate is secured at an angle between horizontal and vertical within an upper end of the column. A lower plate is secured within the column parallel to and spaced beneath the upper plate to define a flow channel between the upper plate and the lower plate. A thermoelectric cooler is connectable to a power source for cooling the upper plate. An accumulator is positioned for collecting and accumulating water that condenses on and flows through the flow channel.
US10022648B2 System for separating and concentrating a liquid component from a liquid multi-component mixture, comprising a heat pump
In order to separate and concentrate a liquid component from a liquid multi-component mixture formed of several liquid components with different boiling temperatures, e.g. an ethanol-water mixture, a concentration apparatus (3) is proposed, with its separation section and concentration section designed as separate columns (5, 7) with different operating energy requirements.The column (7) with the higher operating energy requirements is designed for a lower temperature difference between the boiling temperature of the top of the column (29) and the boiling temperature of the bottom of the column (21) than the column (5) with lower operating energy requirements. Separate mechanical vapour compressors (15, 27) are assigned to the two columns (5, 7), said vapour compressors compressing the vapours from the top of the associated column (5, 7) and supplying the operating energy to the bottom region (11, 21) of the respective column (5, 7) by means of separate sump evaporators (9, 23) which act as, reboilers.
US10022646B1 Solar cooling and water salination system
The solar cooling and water desalination system is a roof-mounted system having a refrigeration unit driven by electricity produced by solar panels to chill water, which is stored in a first tank and used to cool living spaces. Seawater is preheated in a first heat exchanger by waste heat from operation of the refrigeration unit, and heated further in a second heat exchanger by hot distilled water. A field of solar collectors heats oil, which is stored in a hot oil tank and then powers a first boiler to produce high pressure and temperature steam for a steam ejector vacuum system connected to a desalination water boiler that desalinates the seawater, which is condensed by a condenser and stored in a distilled water tank, where it is stored at about 80° C.
US10022645B2 Information providing system and information providing program
[Problem] To provide an educational toy which allows an observed action to be experienced artificially. [Solution] A toy system (900) is used by bringing a magnifying-glass type hand-held instrument (930) into contact with a page (912) of a main body portion (910) having a picture portion (914). The magnifying-glass type hand-held instrument (930) captures an image of the picture portion (914), and determines the location, within the image in said picture portion, that has been captured. From pre-stored image data of a picture image that is the same as the picture portion (914), image data for a part (a partial image) corresponding to the location being captured are then read out and are displayed on a touch panel (942). If the location being captured fulfills certain location conditions, one image element from image elements W41 to W49 is also selected as a special image and is displayed superimposed on the partial image.
US10022643B2 Magnetically coupled accessory for a self-propelled device
A system comprising a self-propelled device and an accessory device. The self-propelled device includes a spherical housing, and a drive system provided within the spherical housing to cause the self-propelled device to roll. When the self-propelled device rolls, the self-propelled device and the accessory device magnetically interact to maintain the accessory device in contact with a top position of the spherical housing relative to an underlying surface on which the spherical housing is rolling on.
US10022639B2 Model vehicle control device and computer program for model vehicle control
A model vehicle control device and method to realize section block control with high extensibility, which can flexibly support various layouts. A section determination unit determines whether a preceding vehicle exists in a section that a vehicle is about to enter. An entry condition determination unit determines, when the vehicle is about to enter a section with constraint, whether a current state in the section satisfies an entry condition. When the current state of the section with constraint does not satisfy the entry condition, a section control unit does not allow entry of a target vehicle to the section, regardless of a determination result of the section determination unit, until the section becomes a state that satisfies the entry condition.
US10022637B2 Hand-held yo-yo ball capable of manually storing energy
The present invention discloses a hand-held yo-yo ball capable of manually storing energy, comprising two rotating bodies and a connecting shaft, where each rotating body comprises a disk body and a shell; one disk body is internally provided with a clutch mechanism, the other disk body is internally provided with an energy storage mechanism; two ends of the connecting shaft are respectively connected with the clutch mechanism and the energy storage mechanism; the rotating body at the end where the clutch mechanism is located is manually rotated, energy is stored in the energy storage mechanism, then the meshing state of the clutch mechanism is manually removed, so that the energy storage mechanism releases the energy to drive the two rotating bodies to rotate synchronously. In this way, the yo-yo ball can be rotated without throwing a ball body of the yo-yo ball by a rope.
US10022636B2 Device for spatial movement of at least one person
A flight simulator, motion simulator or orientation simulator for the spatial movement of at least one person, and in particular for the simulation of acceleration sequences, has a holding device for holding a person in a region of the center. The holding device is mounted on a carriage via a movement device. The carriage can be displaced, in particular linearly, along a horizontally oriented main carrier. The main carrier is rotationally driven about a vertically oriented major axis of rotation and the center is displaceable between a first outer maximum position and a second outer maximum position by moving the carriage along a trajectory on the main carrier. A normal distance between the first outer maximum position of the center and the major axis of rotation is greater than the normal distance between the second outer maximum position of the center and the major axis of rotation.
US10022632B1 Online computer game systems and methods for facilitating financial investment
A computer game system in which real-world financial investment by the player of the computer game is incentivized, and such real-world financial investment is realized as a secondary benefit of game play.
US10022629B2 Information storage medium and game system
A game system includes a character setting section that sets a plurality of characters selected by a player from among a plurality of characters possessed by the player to be battle characters, a game processing section that executes a battle between the characters that have been set to be the battle characters and an enemy character that appears in a stage selected by the player, and an information presentation section that, when a number of times that the player failed to clear the stage has reached a predetermined number, extracts a plurality of characters recommended to be the battle characters from among the characters possessed by the player when the number of times that the player failed to clear the stage has reached a predetermined number, determines whether or not the player can clear the stage when the extracted characters are set to be the battle characters, and presents information that corresponds to the determination result to the player.
US10022627B2 System and method of displaying device information for party formation
A virtual space is provided to users via client computing devices. Device information related to a client computing platform used by a user to interact with the virtual space may be obtained. Customized in-game capabilities available for the user may be determined based on the device information, which may include a description of or otherwise identify the client computing platform. The device information may include or otherwise by used to obtain device capabilities such as hardware, software, network, and/or other specifications. Different users using different client computing platforms may be provided with different in-game capabilities such as user roles, content items, levels, and/or other content or actions available for the user in the virtual space based on the client computing platform used by the users to access the virtual space. The device information may be used to facilitate enhanced party formation between users of the virtual space.
US10022623B2 Ergonomically correct game controller
A hand operated game controller for controlling a game console. Multiple push buttons are arranged on the surface of the game controller. The push buttons are placed in an arrangement that approximately matches the natural position of the fingers of the user's hands. As the user presses the buttons, control signals are sent from the buttons to the game console via wiring.
US10022620B2 Handheld information processing apparatus, storage medium and information processing method
A game apparatus as a handheld information processing apparatus includes a CPU, and when the game apparatus is closed, the CPU shifts to a sleep mode. When a user carries the game apparatus in the sleep mode, a micon measures step counts according to a magnitude of accelerations indicated by acceleration data from an acceleration sensor. When a main power of the game apparatus is turned on to display a main menu screen, the step counts are converted into earned coins, for example. In each of a plurality of applications to be executed by the game apparatus, a special item is purchased, or game playing on a special course is permitted by utilizing the earned coins.
US10022616B1 Digital video recorder for skateboard riser
A skateboard riser is described. The skateboard riser housing and a camera assembly disposed in the housing. A skateboard is also described. The skateboard includes a skateboard deck, a truck, and a riser coupled between the skateboard deck and the truck. The riser includes a camera assembly and a digital video recorder.
US10022610B2 Pole mounted safety restraint for use in mobile fitness vehicle
A pole-mounted individual safety restraint system that incorporates a self-retracting lanyard, suitable for installation and use in vehicles so as to allow exercise or other activity on the vehicle while the vehicle is in motion.
US10022607B1 Row boat for rowing training
A row boat for rowing training includes a hull including a bottom and four sidewalls, and a pair of oars connected to opposing sidewalls, each oar including a handle and an oar scoop disposed as an end of the handle, wherein the oars are configured to rotate about a first axis of rotation to move the oars during a pull phase and a flex phase of a rowing stroke, and wherein the oars are configured to rotate about a second axis of rotation to change an angular orientation of the oar scoop in water during the pull phase and the flex phase.
US10022605B2 Training device for improving reaction capabilities, reflexes, speed and further associated, sports-related, physical and cognitive skills of a user in training
A training device, including: at least two respective response target (7); at least two elastic holder cords (6), each holding said at least one respective response target, wherein each said elastic holder cord (6) is located, in a taut state, between at least one attachment point above a training area and a floor attachment, wherein said at least two holder cords (6) are placed at a distance from one another, with response targets (7) placed thereon, and are connected by a momentum coupling.
US10022602B2 Golf club head with adjustable weighting
A golf club head comprising a means for adjusting the location of the center of gravity and a slidable weight assembly are disclosed herein. The club head comprises two channels, each having at least one shoulder portion, a floor, and a rail extending upwards from the floor. The channels intersect at a junction, and a slidable weight comprising a top portion, a mechanical fastener, a clamping structure, and a keyed, anti-rotation structure is disposed within at least one of the channels. When the mechanical fastener is tightened, the top portion presses against the at least one shoulder portion and pulls the clamping structure upward so that the clamping structure grips the rail. The rails are spaced from one another at the junction, and the clamping structure allows the slidable weight to be moved into either of the channels without being indexed.
US10022599B1 Golf club head with interchangeable rail system
A golf club head with an interchangeable or reversible sole rail system having a rail member configured to be received within one or more channels formed on the club head. The rail system allows the player to employ rails along a surface of the club head to improve the interaction between the club head and the ground during the swing.
US10022597B2 Adjustable length golf clubs and methods of manufacturing adjustable length golf clubs
Embodiments of adjustable length golf clubs and methods of manufacturing adjustable length golf clubs are generally described herein. Other embodiments may be described and claimed.
US10022596B2 Side swing putter
Provided is a putter in golf clubs for use in swinging and putting beside a golf ball while looking at front and keep watching the moving trace of the golf ball, which is titled as a look & watching side swing putter by which a golfer stands at the same point of place where he examined the green grass state and the distance previously, and practices swings while checking the estimated imaginary putting line of the golf ball, and executes putting of the golf ball on the side thereof like bowling while keep watching the golf ball, thereby reducing the putting errors or strokes to wrong directions due to the differences in views direction depending on putting posture and improving straight-line movement of the golf ball at putting.
US10022592B2 Dimple patterns for golf balls
The present invention provides a golf ball wherein each hemisphere has a dimple pattern based on a pyramid having dissimilar sides. The resulting overall dimple pattern is not based on preexisting polyhedral, and is not attainable using conventional dimple packing methods.
US10022591B2 Exercise assistance apparatus determining assistance force and physical fitness equipment having the same
An exercise assistance apparatus includes a mounting unit, a power transmission unit, and an exercise assistance unit. The mounting unit is capable of detaching from a first direction frame of a weight training rack. The mounting unit is mounted on the first direction frame in parallel. The power transmission unit generates a power and transmitting the power. The power transmission unit is arranged at the mounting unit. The exercise assistance unit is coupled movably to the power transmission unit. The exercise assistance unit receives the power and exerting an external force on an exercise assistance and an exercise. The exercise assistance unit includes a housing case, at least one load detection member, a cover member and a microcomputer. The microcomputer calculates an external force value of the power transmission unit based on the calculated value and transmitting a control signal to the power transmission unit based on the external force value.
US10022589B2 Multi-sensor monitoring of athletic performance
Athletic performance monitoring systems and methods, many of which utilize, in some manner, global positioning satellite (“GPS”) data, provide data and information to athletes and/or to equipment used by athletes during an athletic event. Such systems and methods may provide route information to athletes and/or their trainers, e.g., for pre-event planning, goal setting, and calibration purposes. Such systems and methods optionally may provide real time information to the athlete while the event takes place, e.g., to assist in reaching the pre-set goals. Additionally, data and information collected by such systems and methods may assist in post-event analysis for athletes and their trainers, e.g., to evaluate past performances and to assist in improving future performances.
US10022577B2 Pilates machine tension device support system
A Pilates machine tension device support system for efficiently providing a tension force to a movable platform of an exercise machine. The Pilates machine tension device support system generally includes a frame, a platform movably positioned upon the frame and a tension assembly connected between the frame and the platform to provide selective tension upon the platform in a first direction. The tension assembly is comprised of a plurality of pulleys and a plurality of tension devices positioned upon the pulleys, wherein the tension devices are attached between a frame and the platform. The tension members are selectively engaged to the platform to increase or decrease the tension applied to the platform for varying levels of workouts.
US10022575B2 Antifreeze sprinkler system
An antifreeze fire protection sprinkler system is provided including a water supply and a water distribution pipe system having a plurality of segments disposed in a potentially freezing environment and having a check valve and a plurality of fire protection sprinklers disposed in each segment wherein the plurality of fire protection sprinklers are designed to limit the atomization of the antifreeze solution. A pressure regulating device is disposed in the water distribution pipe system for limiting a maximum pressure of water supplied to the water distribution pipe system.
US10022571B2 Rescue descender system
A descender system, typically for use in a fall arrest system, for enabling a suspended body to be lowered includes a rotatable descent line drum, and a release element arranged in a restraint configuration to inhibit the descent line from being deployed and in a release configuration to permit the descent line to be deployed. A rotating brake applies a braking force to the rotatable descent line drum; a gear train connects the brake to the drum. The gear train is provided in a substantially watertight sealed space. Typically, a substantially watertight seal is provided between a backplate of the rotating drum and a chassis of the device. Typically, the substantially watertight seal is of a material that is deformable/compressible, preferably at temperatures at or below −20 Celsius.
US10022565B2 External beam radiotherapy and imaging with radioactive isotope
A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.
US10022563B2 Image-guided radiotherapy
A radiotherapy apparatus comprises a rotatable gantry, supporting a source of therapeutic radiation and a source of diagnostic radiation, the two sources being rotationally (or angularly) spaced apart around a rotation axis of the gantry, with at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a control means arranged to conduct a treatment fraction using the apparatus by causing the apparatus to i. acquire images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. subsequently, after further rotation of the gantry, select a retained image acquired when the source of diagnostic radiation was at a rotational position corresponding to the instantaneous rotational position of the source of therapeutic radiation, and iv. control the beam relative to the patient using information derived from the selected image. The corresponding rotational position is ideally one in which the source of therapeutic radiation is at the same or substantially the same rotational position as was the source of diagnostic radiation at the point in time when the image was acquired. An alternative a radiotherapy apparatus comprises a rotatable gantry supporting a source of therapeutic radiation and a source of diagnostic radiation, at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a reconstruction means arranged to i. obtain two-dimensional images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. apply a recency threshold to the retained images thereby to exclude images less recent than the threshold, iv. select at least three such retained images meeting the recency threshold and reconstruct a CT volume or tomographic image using the selected images, and a control means arranged to conduct a treatment fraction or treatment session using the apparatus, controlling the collimator using information derived from the CT volume.
US10022559B2 Method and device for improved radiation therapy treatment of a set of targets
A medical data processing method for determining a target set comprising at least one irradiation target in a patient's body for radiation therapy treatment by means of a treatment device constituted to treat the at least one target by means of one or more sub-beams during a treatment time, the one or more sub-beams constituting at least one treatment beam which is to pass through the at least one target in accordance with a treatment plan during the treatment time, the method comprising the following steps and being constituted to be executed by a computer: a) acquiring (S 1.1) critical area; b) acquiring (S 1.2) target data; c) acquiring (S 1.3) treatment beam constraint data; d) acquiring treatment beam criteria data (S 1.4); and e) determining (S4), based on the critical area data, the target data, the treatment beam constraint data and the treatment beam criteria data, target set data describing spatial information on at least one irradiation region.
US10022558B1 Methods and devices for minimally-invasive delivery of radiation to the eye
Methods and devices for minimally-invasive delivery of radiation to the posterior portion of the eye including a cannula comprising a distal portion connected to a proximal portion and a means for advancing a radionuclide brachytherapy source (RBS) toward the tip of the distal portion; a method of introducing radiation to the human eye comprising inserting a cannula between the Tenon's capsule and the sclera of the human eye and emitting the radiation from the cannula.
US10022557B2 Using a guided member to facilitate brachytherapy device swap
A guide member facilitates a device swap for brachytherapy treatment. A cavity evaluation device is introduced during surgery such that a distal end of the device is disposed in a resected cavity of the patient. The cavity evaluation device includes a shaft in which is disposed an elongated guide member. In a subsequent out-patient procedure the cavity evaluation device is removed from the resected cavity. If a brachytherapy treatment is to be performed then the cavity evaluation device is removed without removing the elongated guide member such that position of a portion of the elongated guide member in the resected cavity is maintained relative to the resected cavity. An anchor member helps to maintain the position of the guide member. Introduction of a brachytherapy catheter is then facilitated by introducing the elongated guide member into an opening of the brachytherapy catheter and using the elongated guide member to guide the brachytherapy catheter to the resected cavity.
US10022556B1 Computer controlled solid state lighting assembly to emulate diurnal cycle and improve circadian rhythm control
A light system can simultaneously emulate more than one different diurnal cycle to individually improve circadian rhythm control for more than one observer by having each light fixture autonomously self-controlled. Each light fixture is mountable in respective locations to individually treat respective observers. Each light fixture includes one or more light elements mounted to a housing and are controllable to emit a selected light intensity at a selected light temperature. A micro controller is contained in the housing and includes memory containing instructions for one or more automatic diurnal cycle protocols. The micro controller is in communication with the memory and the one or more light elements to execute the instructions to configure the light fixture to vary the light intensity and the light temperature of the emitted light.
US10022555B2 Light therapy bandage system
A radiant energy bandage system is disclosed including a plurality of therapeutic lamps and a controller for operating the lamps. Batteries power the lamps and are secured to a wearable fabric layer supporting the lamps and the controller. According to an exemplary embodiment, provided is a phototherapy device comprising a stretchable and/or flexible wearable therapeutic lamp platform including a plurality of radiant lamps configured to provide radiant energy to a user treatment area, a stretchable and/or flexible reflective wall including a plurality of radiant energy communication areas aligned with the radiant lamps and disposed to communicate the radiant energy to the user treatment area; and a stretchable and/or flexible adhesive layer including a first surface and a second surface, the first surface removably attached to the reflective layer and the second surface operatively associated with removably attaching the wearable therapeutic lamp platform to the user treatment area.
US10022554B2 Light therapy bandage system
The radiant energy bandage system is disclosed including a plurality of therapeutic lamps and a controller for operating the lamps. Batteries power the lamps and are secured to a flexible fabric layer supporting the lamps and the controller. A foam and reflective layer includes a spacer foam and radiant energy reflector. A plurality of spacer windows are aligned with the lamps for communicating lamp radiation therethrough. A sheer mesh fabric layer is supposed to cover the foam and reflective layer.
US10022552B2 System and method for optogenetic therapy
Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.
US10022542B2 Low power cochlear implants
In one aspect, the disclosure features systems for providing auditory signals to a subject. The systems include a sensor front-end circuit configured to be connected to an acoustic sensor and to convert analog signals received from the acoustic sensor to digital electric signals. The systems further include a sound processor circuit configured to be connected to the sensor front-end circuit and receive the electric signals provided by the sensor front end circuit. The sound processor includes multiple filters that spectrally decompose the received electrical signals into multiple spectral channels during operation of the system. The multiple spectral channels include at least a low frequency channel and a high frequency channel and the sound processor circuit is configured to operate the low frequency channel at a sample rate lower than a sample rate of the high frequency channel.
US10022541B2 Electro-stimulation device and method of systematically compounded modulation of current intensity with other output parameters for affecting biological tissues
A non-user controllable electro-therapy device has a housing for a microprocessor, power source, status indicator, activation switch, and one or more channels for electrode contact. Only the activation switch is user-accessible. The microprocessor generates a non-user controllable frequency dependent mixed electrical signal through the electrodes, wherein the mixed electrical signal is a combination of at least two different frequencies, a first frequency having a first minimum and maximum microamp range and a second frequency having a different second minimum and maximum microamp range. The higher of the two frequencies is superimposed on the lower frequency, creating a current intensity window as an envelope along a profile of the lower frequency. The mixed electrical signal is automatically applied for a pre-determined period of time, and amplitude and/or duration and/or frequencies is varied according to a pre-set schedule programmed into a controller coupled to the one or more electrodes.
US10022536B2 Electrode structure and method for producing
One aspect relates to a method of producing an electrode structure, including producing a longitudinal body having a core and at least one layer made of an electrode material surrounding the core. A part of the layer made of electrode material is removed while forming a plurality of electrodes that are arranged such as to be distributed in the longitudinal direction and which are separated from each other, and contact paths that extend in the longitudinal direction and adjoin the electrodes, each, as the same part. A layer made of a polymeric material is applied while embedding, at least in part, the electrodes and/or contact paths.
US10022517B2 System, and process, and device for emission or augmentation of energy affecting the human body
A chip may be programmed to emit and/or augment energy tuned to interact with bodily functions through transdermal contact. The chip may be programmed by using a pair of Tesla pancake coils, each coupled to a spherical electrode and driven to create an energetic field between the electrodes. Embodiments may include systems that include the programmed chip in a fabric body. The systems may be wearable so that the effects of the programmed chip may be applied to selected areas of the human body. Some embodiments may be useful for augmenting healing of ailments.
US10022516B2 Apparatus and method for treating a neuromuscular defect
A method is provided for treating a neuromuscular defect in a subject. One step of the method includes locating a target nerve. After locating the target nerve, a treatment probe is provided. The treatment probe includes an elongated body member having a proximal end portion and a distal end portion. The distal end portion includes an energy delivery mechanism for stimulating or ablating the target nerve, a monitoring mechanism, and a fluid aspiration/delivery mechanism. Next, the target nerve is verified as an appropriate target for ablation by stimulating and then monitoring the target nerve via the energy delivery mechanism and the monitoring mechanism, respectively. After verifying the target nerve, a tumescent fluid is injected into the tissue surrounding the target nerve. An electric current is then delivered to the energy delivery mechanism to substantially ablate the target nerve.
US10022512B2 System and method for synchronization of breathing in a mechanical ventilator
Example embodiments presented herein are directed towards a system, and corresponding method, for providing ventilation synchronization between breathing gas supplied by a mechanical ventilator and the breathing needs of a patient. In providing the ventilation synchronization, a total amount of energy required during an inspiratory phase of breathing is calculated. Based on the calculated energy, a decay factor is determined. The decay factor is supplied to an inspiratory triggering system in order to provide the ventilation synchronization.
US10022507B2 Intravenous fluid warming system
A fluid warming device may include a housing comprising a main body, a heat exchange body receiving compartment, and a cover movably coupled to the main body between an open position and a closed position; a heater assembly disposed within the main body and having a heat conducting surface disposed proximate the heat exchange body receiving compartment; and a heat exchange body removably disposable in the heat exchange body receiving compartment of the main body and having an input port and an output port to couple the heat exchange body to tubing to flow a fluid to be warmed through the heat exchange body. In another aspect, a fluid warming system increases or decreases power to a heater assembly to adjust the fluid temperature to ensure that the fluid is at an appropriate temperature when it reaches the patient.
US10022504B2 Separable hub post of pen needle
A pen needle (101) for use with a drug delivery device (100) includes a hub body (113) having internal threads (216) to receive the drug delivery device (100). A post (121) is connected to the hub body (113). A needle (103) is rigidly fixed to the post (121). The post (121) is separable from the hub body (113) such that the needle (103) is removed with the post (121). The fluid path is not disturbed by such removal because the entire needle (103) is removed with the post (121). Removal of only the post (121) and needle (103) reduces the volume of waste required for disposal, thereby increasing the effective capacity of a sharps container.
US10022496B2 Sensor device for use in a medical fluid delivery system
A sensor device for use in a medical fluid delivery system, or an infusion pump device, comprises a fluidic chamber with a deformable cover closing at least an area of the chamber and an optical detection system comprising at least one light emitter for emitting one or more incident light beams and a sensor unit for monitoring one or more reflected light beams is presented. In a pressurized state of the fluidic chamber, the deformable cover is deformed such that it forms an inflexion point area within the deformed cover. The one or more incident light beams emitted by the light emitter are directed on the cover such that the one or more incident light beams are reflected essentially in the inflexion point area.
US10022495B2 Fluid line occlusion detection system and methods
The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.
US10022491B2 System and method for insulin pump medical device including a slider assembly wherein images on display allow for highlighting and magnifying images
A medical system includes an input assembly for receiving one or more user inputs. The input assembly includes at least one slider assembly for providing an input signal. Processing logic receives the input signal from the input assembly and provides a first output signal and a second output signal. A display assembly is configured to receive, at least in part, the first output signal from the processing logic and render information viewable by the user. The second output signal is provided to one or more medical system components. The information rendered on the display assembly may be manipulatable by the user and at least a portion of the information rendered may be magnified.
US10022488B2 Systems and methods for cleaning body cavities
Systems and methods for cleaning body cavities are presented. Some embodiments reduce size of fecal matter pieces within an evacuation conduit. Some comprise devices and methods for purging an evacuation conduit. Some comprise reduced cross-sectional profiles of a cleaning device. Some protect intestinal tissue by preventing exposure to excessively high and low pressures.
US10022487B2 Single collection bag blood collection system, method and apparatus
A blood or blood component collection and processing system, apparatus and method are disclosed. One embodiment includes a vascular access device and a blood collection container having a blood inlet and first and second blood component outlets. The outlets are located at opposite ends of the container, and a blood flow conduit extends between the vascular access device and collection container. The collection container is free of attachment to other blood collection containers when in an initial collection configuration at the time of collection.
US10022486B2 Device, system, and method including micro-patterned cell treatment array
Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types.
US10022485B2 Device and method for monitoring an extracorporeal blood treatment
A device and method for monitoring an access to a patient, an extracorporeal blood circuit and/or a dialyzing fluid system includes a centrifugal pump for conveying blood or dialyzing fluid instead of an occluding pump. Centrifugal pumps bring about a large change in flow rate by even a small change in pressure difference across the pump. The device includes a measuring unit for measuring the flow rate of blood or dialyzing fluid conveyed by the centrifugal pump, and a control and computing unit configured to determine an incorrect vascular access or malfunction if a change in measured flow rate Q is more than a predetermined amount. For example, a small drop in pressure in the venous blood line leads to a marked increase in the flow rate of the centrifugal pump, which is used as a basis for the detection of an incorrect vascular access.
US10022480B2 Ventricular assist device and method of controlling same
The invention relates to a method of controlling the speed of a ventricular assist device, in particular the rotational speed of a rotary blood pump, wherein at least temporarily the speed of the device is modulated around a mean speed and a response of the native heart to this modulation is measured to determine the ventricular function/contractile state of the heart, in particular to determine whether the aortic valve opens and closes at the instant mean speed, and the mean speed is set, in particular a new mean speed is set in dependence of the measured response. The invention furthermore relates to a device performing the method.
US10022479B2 Suction device for surgical instruments
A suction device is shown and described. The suction device includes a body, an input port configured to receive a flow of matter, a suction port, and a suction lumen that couples the suction port to the input port. In some embodiments the suction device is configured to couple with a surgical instrument for use in a surgical procedure.
US10022471B2 Calcium phosphate cements and methods for using the same
Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a setting fluid to produce the flowable composition. A feature of the subject methods is that the dry reactants include a particulate calcium and/or phosphate reactant having a mean particle size of less than about 8 μm and narrow size distribution. Also provided are the compositions themselves as well as kits for use in practicing the subject methods. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g., bone defects.
US10022470B2 High-strength and bio-absorbable magnesium alloys
A microalloyed magnesium material for absorption in the body of a human or animal. The microalloyed magnesium material consists of: 0.85 to 1.4 percent by weight of zinc (Zn), 0.2 to 0.5 percent by weight of calcium (Ca), 0.2 to 0.5 percent by weight of manganese (Mn) with the remainder being magnesium (Mg) and inevitable impurities.
US10022469B2 Microspheres useful for therapeutic vascular embolization
Provided herein, for example, are microspheres comprising a gelatin or gelatin substitute and a copolymer of a N-tris-hydroxymethyl methylacrylamide monomer unit, a diethylaminoethylacrylamide monomer unit and a N,N-methylene-bis-acrylamide monomer unit. Also provided are methods of producing microspheres comprising a gelatin or gelatin substitute and a copolymer of a N-tris-hydroxymethyl methylacrylamide monomer unit, a diethylaminoethylacrylamide monomer unit and a N,N-methylene-bis-acrylamide monomer unit. Further provided herein, for example, are compositions comprising the microspheres and methods of using the microspheres and compositions thereof.
US10022468B2 Absorbent articles containing a multifunctional gel
Improved skin-adhesive compositions for bonding a substrate, such as an absorbent article, to skin are disclosed. More particularly, the skin-adhesive composition has an improved, yet gentle, adhesion to the skin of a user, while maintaining strong, effective bonding to various inanimate, non-skin substrates. In one embodiment, the skin-adhesive composition can provide one or more skin benefit agents to the user. The skin-adhesive composition may be applied to an absorbent article, such as a panty-liner, sanitary napkin, or an incontinence article, for directly adhering the article to the skin of a user.
US10022466B2 Synchronous control of lamp brightness and sample diffusion
In response to user interaction, a signal is generated from a control element of a sample diffuser assembly. The sample diffuser assembly comprises a sample container, wherein the sample container is configured to receive a sample to be diffused; a motor operative to assist in diffusing the sample at a selectable transformation rate; a light source, wherein the light source comprises an AC lamp; and control circuitry operatively coupled to the motor and the light source. A set of signals is generated, via the control circuitry in response to the signal generated by the control element, wherein the set of signals simultaneously control the light intensity of the AC lamp based on the transformation rate produced by the motor to diffuse the sample in the sample container.
US10022464B2 Sterilization tray
An apparatus for sterilizing items and storing the sterilized items prior to use includes a container configured to receive items to be sterilized, a trap door coupled with the container, and a mechanism operatively coupled with the trap door and the container. The trap door is reconfigurable between an open configuration providing a fluid passage into the apparatus and a closed configuration in which the items are hermetically sealed within the apparatus. The mechanism is configured for selective reconfiguration of the trap door from the closed configuration to the open configuration and to automatically reconfigure the trap door from the open configuration to the closed configuration after completion of a sterilization of items disposed within the apparatus.
US10022463B2 Device and method for continuous virus inactivation
The invention provides an apparatus and a process for continuous virus inactivation. The apparatus for continuous virus inactivation in a product stream comprises a tube or hose 1 having an inlet 4 and an outlet 5 in each case connected to a product flow line 8 for conveying the product stream, where the tube or the hose 1 is curved and/or helically coiled with a number n of windings around a coil axis h and has one or more changes in direction and/or bends 2 in the coil axis h having an angle α of from 45° to 180° to alter the direction of action of the normals of the centrifugal force and the apparatus is characterized by a Dean number>0 and a torsion parameter>0.
US10022459B2 Medical tissue-marker and manufacturing method for the same
A medical tissue-marker which enables the identification of a location even from the outside of an organ, can remain topical over a long period, and enables the easy identification of a marked location within the whole organ; also a manufacturing method for the medical tissue-marker. The medical tissue-marker includes a vesicle formed by the synthesis of a phospholipid and a near infrared fluorescent dye, and an emulsion formed by the synthesis of the phospholipid and an X-ray contrast medium, and has agglomerated clusters wherein the vesicle and the emulsion are contained in a hydrophilic solvent and a plurality of capsules are formed by use of an emulsifier.
US10022455B2 Biodegradable lipids for delivery of nucleic acids
The present invention provides, in part, a biodegradable compound of formula I, and sub-formulas thereof: Formula (I) or a pharmaceutically acceptable salt thereof, where each X independently is O or S, each Y independently is O or S, and each R1 independently is defined herein; and a liposome composition comprising the cationic lipid of formula I or a sub-formula thereof, and methods of delivering agents, such as nucleic acids including mRNA, in vivo, by administering to a subject the liposome comprising the cationic lipid of formula I or a sub-formula thereof, where the agent is encapsulated within the liposome.
US10022453B2 Antibody drug conjugates (ADCs) with kinesin spindel protein (KSP)
The present application relates to novel antibody drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.
US10022450B2 Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
US10022448B2 Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent
A composition comprising: a benefit agent; at least one polymer including a polycaprolactone polymer; at least one lower alcohol; and at least one co-solvent; and a method for enhancing topical delivery of a benefit agent is disclosed.
US10022444B2 Combination therapy involving antibodies against Claudin 18.2 for treatment of cancer
The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.
US10022432B2 Malaria antigens and methods of use
The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.