最新美国发明专利第2014-03-04期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08664527B2	Cable interface furniture for a conference table The object of the invention is a cable interface furniture for a conference table, which cable interface furniture comprises at least a space enabling connections that is disposed below an openable and closable table hatch in the table. The cable interface furniture comprises a casing extending from the bottom upwards that is intended to be placed under and that stands on the floor resting on support means that are adjustable in their height, the top part of which casing contains a bed provided with at least lead-in apertures, above which is a space enabling connections, with at least the connectors of the connecting cables being supported in which bed, and which connecting cables are fitted when free to be disposed in the space below the intermediate bed in the casing.
US08664522B2	Method for producing a thin-film solar cell by use of microcrystalline silicon and a layer sequence A thin film solar cell is disclosed comprising the following layers deposited on a substrate: a microcrystalline p- or n-layer, an intermediate microcrystalline silicon i-layer applied by a hot-wire chemical-vapor deposition (HWCVD) method on the microcrystalline p- or n-layer a), an additional i-layer of microcrystalline silicon, which is formed by depositing on the intermediate microcrystalline silicon i-layer, by a plasma enhanced chemical vapor deposition (PECVD), a sputtering process, or a photo-CVD method whereby layers b) and c) together form an i-layer, and if a p-layer is present as the layer of step a), an n-layer, and if an n-layer is present as the layer of step a), a p-layer that is either microcrystalline or amorphous.
US08664520B2	Electrode of solar cell Provided is an electrode of a solar cell including a first electrode layer, a photoelectric conversion layer, an antireflective layer, and a second electrode layer. The first electrode layer is disposed on the photoelectric conversion layer. The antireflective layer is disposed on the photoelectric conversion layer to cover the first electrode layer. The second electrode layer is disposed on the antireflective layer and electrically connected to the first electrode layer, wherein a material of the first electrode layer does not react with the photoelectric conversion layer and the antireflective layer during a sintering process, and at least a material of the second electrode layer reacts with the antireflective layer during the sintering process.
US08664516B2	Structure and method of solar cell efficiency improvement by strain technology A structure and a method of the solar cell efficiency improvement by the strain technology are provided. The solar cell has a first surface and a second surfaces which at least a gasket is disposed thereon for supporting the solar cell and being the axle whiling stressing. The method includes the steps of: (a) applying at least a stress on the first surface; (b) generating a supporting force on the second surface; and (c) generating at least a strain in the solar cell. In addition, the present invention also includes a method involving a step of: (a) applying a mechanical stress to the solar cell; (b) generating a tension in the solar cell by at least two materials having different lattice constants; or (c) generating another tension in the solar cell by a shallow trench isolation filler, a high tensile/compressive stress silicon nitride layer and a combination thereof.
US08664512B2	Photovoltaic module The present invention provides a photovoltaic module with bypass diodes that has a high electricity generating capacity per unit area and high productivity. This photovoltaic module includes a photovoltaic cell assembly in which a plurality of photovoltaic cells are electrically connected in series, and a diode assembly in which a plurality of diodes are formed on a substrate in the arrangement that is consistent with the arrangement of the photovoltaic cells to which the diodes are to be attached. The diode assembly is disposed on a non-light receiving side of the photovoltaic cells, and the diodes are electrically connected to the photovoltaic cells. The photovoltaic cell assembly and the diode assembly are sealed and united by a sealant.
US08664511B2	Solar module Solar module with a plurality of lamellar solar panels, which are mounted on an elongated support to pivot around a common axis and are movable between a first position in which they are superposed to be substantially congruent and parallel to the support, and a second position in which, opened out in a fan formation, they lie substantially adjacent to one another around the said axis, wherein the support can be extended via a closable opening out of a housing, which receives it with the solar panels in the first position.
US08664509B2	Thermoelectric apparatus and method of fabricating the same A thermoelectric apparatus includes a first and a second assemblies, at least a first and a second heat conductors. The first assembly includes a first and a second substrates, and several first thermoelectric material sets disposed between the first and second substrates. The first substrate has at least a first through hole. The second assembly includes a third and a fourth substrates, and several second thermoelectric material sets disposed between the third and fourth substrates. The fourth substrate has at least a second through hole. Each of the first and second thermoelectric material sets has a p-type and an n-type thermoelectric element. The first and second heat conductors respectively penetrate the first and second through holes. Two ends of the first heat conductor respectively connect the second and fourth substrates, while two ends of the second heat conductor respectively connect the first and third substrates.
US08664507B1	Musical instrument pickup and methods Musical instrument pickups and methods of constructing same to achieve a user-desired signal output level and a user-desired tonal characteristic from a stringed instrument are disclosed. The method may include steps for selecting a coil geometry, selecting a number of coils, selecting a coil wire gauge and number of turns for each coil and selecting a pole piece. In selecting the pole piece consideration may be given to pole piece composition, pole piece thickness, height and width, and pole piece response in terms of relative inductive and relative resonant frequency characteristics and/or the shape of the frequency response in the vicinity of resonance.
US08664506B2	Electronic percussion instrument and recording medium with program recorded therein An electronic percussion instrument including: a detecting section which is provided in a stick and detects acceleration and angular speed based on movement of the stick; a first timing generating section which generates beat timing based on a predetermined tempo and beat width; a first pre-sound-production movement detecting section which detects a pre-sound-production movement that is performed prior to sound production, based on the acceleration and the angular speed detected by the detecting section; and a sound production instructing section which instructs to produce a sound at the beat timing generated by the first timing generating section, when the first pre-sound-production movement detecting section detects the pre-sound-production movement.
US08664500B2	Musical instrument stand A drum stand includes a center pipe, a fixed collar, a first movable collar, a second movable collar, legs, and stays. The fixed collar is secured to the lower end of the center pipe. The first movable collar and the second movable collar are slidably fitted to the center pipe. Legs of a first type are pivotally coupled to the first movable collar. A leg of a second type is pivotally coupled to the second movable collar. Stays of a first type are pivotally coupled to the second movable collar. A stay of a second type is pivotally coupled to the fixed collar.
US08664499B2	Nose pipe instrument capable of modulating the tone thereof Disclosed is a nose pipe instrument capable of modulating the tone thereof. The nose pipe instrument capable of modulating the tone thereof enables a modulating plate to slide to adjust the length of a sealing path for the passage of breath from the nose of a player. Thus, the nose pipe instrument of the present invention can modulate the pitch of the tone to be played, thereby enabling various notes to be played.
US08664497B2	Double keyboard piano system A double keyboard piano system is provided. The double keyboard piano system may include a first automatic player piano, a second automatic player piano, and a double keyboard console including a first keyboard and a second keyboard mounted above the first keyboard. The first automatic player piano is in communication with the double keyboard console to receive a first signal including first information describing a first key for the first automatic player piano to automatically play based on a first key of the first keyboard being played, and the second automatic player piano is in communication with the double keyboard console to receive a second signal including second information describing a second key for the second automatic player piano to automatically play based on a second key of the second keyboard being played.
US08664493B2	Plants and seeds of corn variety CV425548 According to the invention, there is provided seed and plants of the corn variety designated CV425548. The invention thus relates to the plants, seeds and tissue cultures of the variety CV425548, and to methods for producing a corn plant produced by crossing a corn plant of variety CV425548 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV425548 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV425548.
US08664492B2	Plants and seeds of corn variety CV197629 According to the invention, there is provided seed and plants of the corn variety designated CV197629. The invention thus relates to the plants, seeds and tissue cultures of the variety CV197629, and to methods for producing a corn plant produced by crossing a corn plant of variety CV197629 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV197629 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV197629.
US08664489B2	Maize inbred PH1DAY A novel maize variety designated PH1DAY and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1DAY with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1DAY through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1DAY or a locus conversion of PH1DAY with another maize variety.
US08664488B1	Maize hybrid X85C455 A novel maize variety designated X85C455 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X85C455 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X85C455 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X85C455, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X85C455. This invention further relates to methods for producing maize varieties derived from maize variety X85C455.
US08664486B2	Plants and seeds of hybrid corn variety CH332645 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH332645. The invention thus relates to the plants, seeds and tissue cultures of the variety CH332645, and to methods for producing a corn plant produced by crossing a corn plant of variety CH332645 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH332645.
US08664485B1	Maize variety hybrid X7H283 A novel maize variety designated X7H283 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X7H283 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X7H283 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X7H283, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X7H283. This invention further relates to methods for producing maize varieties derived from maize variety X7H283.
US08664484B1	Maize variety hybrid X05B914 A novel maize variety designated X05B914 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X05B914 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X05B914 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X05B914, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X05B914. This invention further relates to methods for producing maize varieties derived from maize variety X05B914.
US08664474B2	Plants and seeds of hybrid corn variety CH982859 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH982859. The invention thus relates to the plants, seeds and tissue cultures of the variety CH982859, and to methods for producing a corn plant produced by crossing a corn plant of variety CH982859 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH982859.
US08664465B2	Injection and hemostasis site A pad of elastomeric material having a softness of no more than about durometer 50 Shore 00. The pad may carry adhesive and/or a housing for adhering the pad to a surface, either directly or indirectly through an envelope which surrounds the pad and carries the adhesive. Such a pad exhibits hemostatic and leak prevention properties against needle puncture holes in the skin or the wall of a hollow medical device. Particularly, hemostasis may be prevented with low pressure application of the pad to the skin. The pad may be previously applied to the skin of the patient or a wall of a medical device such as tubing or a solution bag, and the needle may then penetrate both the pad and the skin or medical device wall, to make a resealable puncture with leakage reduction and hemostasis when the needle is withdrawn.
US08664454B2	Process for production of ethanol using a mixed feed using copper containing catalyst The present invention produces ethanol in a reactor that comprises a catalyst comprising from 40 to 70 wt. % copper and 15 to 40 wt. % zinc and a support material. The crude ethanol product may be separated and ethanol recovered.
US08664452B2	Process for preparing extra pure 2, 6-diisopropyl phenol Disclosed herein is a process for the preparation of highly pure 2,6-diisopropyl phenol (Formula I), which comprises reacting p-hydroxy benzoic acid (Formula II) with an alkylating agent in presence of aq. mineral acid followed by basification and subsequent washings to yield 4-hydroxy-3,5-diisopropylbenzoic acid (Formula III) free of dimer impurity, 4,4′-oxydibenzoic acid of Formula IV, ether impurity 3,5-di(propan-2-yl)-4-(propan-2-yloxy)benzoic acid of Formula V and the monoalkylated impurity 4-hydroxy-3-(propan-2-yl)benzoic acid of Formula VI; and decarboxylating 4-hydroxy-3,5-diisopropylbenzoic acid (Formula III) in presence of high boiling solvent and sodium hydroxide as a catalyst at high temperature to yield 2,6-diisopropyl phenol substantially free of ether impurity 1,3-di(propan-2-yl)-2-(propan-2-yloxy)benzene of Formula VII and monoalkylated phenol impurity 2-(propan-2-yl) phenol of Formula VIII. Propofol prepared by the process of the present invention is suitable for pharmaceutical use.
US08664451B2	Controlling the normal:ISO aldehyde ratio in a mixed ligand hydroformylation process by controlling the olefin partial pressure Control of an in-series, multiple, e.g., two, reaction zone, hydroformylation process for producing normal (N) and iso (I) aldehydes at a N:I ratio, the process comprising contacting an olefinically unsaturated compound, e.g., propylene, with carbon monoxide, hydrogen and a catalyst comprising (A) a transition metal, e.g., rhodium, (B) an organobisphosphite, and (C) an organomonophosphite ligand, the contacting conducted in first and subsequent reaction zones and at hydroformylation conditions comprising an olefinically unsaturated compound partial pressure in each zone, the control exercised by decreasing the olefinically unsaturated compound partial pressure in the first reaction zone to decrease the N:I ratio or increasing the olefinically unsaturated compound partial pressure in the first reaction zone to increase the N:I ratio.
US08664450B2	Manufacture of gamma-delta-unsaturated ketones A process for the manufacture of gamma-delta-unsaturated ketones of formula (R1)(R2)C═CH—CH2—CH2—CO—R3 (I), wherein R1 is methyl or ethyl; R2 is a saturated or unsaturated linear or cyclic hydrocarbon residue and R3 is methyl or ethyl, by reacting a tertiary vinyl carbinol of formula (R1)(R2)C(OH)—CH═CH2 (II) with an isopropenyl methyl or ethyl ether of formula H3C—C(OR3)═CH2 (III) in the pre-sence of an ammonium salt as catalyst.
US08664448B2	Process for the production and purification of propylene glycol The present invention relates to a process for producing an odorless and colorless industrial grade propylene glycol from glycerol obtained during the manufacturing of biodiesel. The process includes hydrogenating the glycerol to form a hydrogenated product, distilling the hydrogenated product to form a glycol product, and contacting the glycol product with a treatment bed. The propylene glycol may be used in various industrial and consumer applications and products such as personal care products.
US08664447B2	Process for the oxidation of hydrocarbons with the use of iridium metal catalyst complexes Provided is a process for effectively and efficiently oxidizing alkyl-containing molecules with the use of an oxygen-containing gas. An iridium metal catalyst complex with the iridium being coordinated with the nitrogen atoms of a benzimidazolyl-containing ligand is used as the catalyst. The process generates alcohols, ketones and aldehydes directly from alkyl-containing molecules and/or aromatic molecules.
US08664446B1	Purification of trimethylamine Methods of purifying NMe3 by removing N2, NH2Me, NH3, and H2O are disclosed.
US08664440B2	Method for preparing aliskiren and its intermediates thereof A method for preparing Aliskiren and intermediate thereof, which comprises the following steps: reacting 4-bromo-1-methoxy-2-(3-methoxypropoxy)benzene with magnesium isopropyl chloride and n-BuLi to obtain the compound of formula XXII; reacting the product of methylsulfonylation of the compound of formula XIX with anhydrous LiBr to obtain the compound of formula XXI; obtaining the intermediate of Aliskiren shown as formula XV by reacting the compound of formula XXII with the compound of formula XXI in an ether as the solvent and in the presence of a catalyst containing iron; then reacting the compound of formula XV with the compound of formula VII to obtain the compound of formula XXIII, following removing R1 from the amino group and obtaining Aliskiren shown as formula I.
US08664435B2	Liquid lactic acid composition and method for preparation thereof A method of preparing a liquid lactic acid composition that has a total acid content of at least 94% (w/w) and that does not crystallize at a temperature above 10° C. includes obtaining a starting liquid lactic acid composition that has a total acid content of at least 94% (w/w) and that crystallizes at a temperature above 10° C. and incubating said starting liquid lactic acid composition at a temperature above the crystallization point of the starting liquid lactic acid composition for a time period to obtain the liquid lactic acid composition that does not crystallize at a temperature above 10° C.
US08664433B2	Synthesis of 4-[3-(2,6-dimethylbenzyloxy)phenyl]-4-oxobutanoic acid The compound 4-[3-(2,6-Dimethylbenzyloxy)phenyl]-4-oxobutanoic acid (DPA) is synthesized from 1-[3-(2,6-Dimethylbenzyloxy)-phenyl]-ethanone (DPE) via the intermediate 4-[3-(2,6-Dimethylbenzyloxy)phenyl]-4-oxobulanoic acid ethyl ester (DPAE).
US08664431B2	Preparation method of copolymerizable photoinitiators An intermediate for preparing (meth)acrylated photoinitiators according to Formula (I): wherein: R1 is selected from the group consisting of hydrogen and a methyl group; A represents a group including at least one photoinitiating moiety; L represents a n+o-valent linking group including at least one carbon atom; n and o each independently represent an integer from 1 to 4; p is equal to 0 or 1; X represents a group selected from the group consisting of CI, Br, I, and R2SO3; and R2 represents an optionally substituted group selected from the group consisting of an alkyl group, an alkenyl group, an alkynyl group, an alkaryl group-, an aralkyl group, an aryl group and a heteroaryl group. Also, a method for the preparation of (meth)acrylated photoinitiators by β-elimination of HX from the intermediate according to Formula (I).
US08664427B2	Process for preparing highly branched polyhydroxybenzoic acid alkoxylates The invention relates to a process for preparing hyperbranched polyhydroxybenzoic acid alkoxylates, comprising the steps of: (a) reacting at least one polyhydroxybenzoic ester with one or more alkylene oxides, optionally in the presence of a basic catalyst, (b) allowing the polyhydroxybenzoic ester alkoxylates formed in step (a) to react with transesterification to form hyperbranched polyhydroxybenzoic acid alkoxylates.
US08664420B2	Process for production of zinc toluenesulfonate, zinc toluenesulfonate, and process for production of carbamate A process for producing zinc toluenesulfonate comprising reacting a zinc compound comprising Zn(OH)2 with toluenesulfonic acid and/or a salt thereof in the presence of an alcohol having 1 to 20 carbon atoms in total at a temperature higher than 60° C.
US08664419B2	Acetylene storage using metal-organic frameworks of the formula M2(2,5-dihydroxyterephthalate) This invention provides, but is not limited to, methods of using metal-organic frameworks (MOFs) having repeat units of the formula M2(DHTP) (M is a divalent metal ion; DHTP=2,5-dihydroxyterephthalate) for acetylene storage. Also provided are compositions of the same formula and acetylene, e.g., an acetylene storage material comprising [M2(DHTP)]n and acetylene.
US08664417B2	Process for the synthesis of 4-(dimethylsilyl) butylferrocene The invention provides for a process for the preparation of a silylferrocene compound, comprising the steps of treating ferrocene with a 4-chloroalkyryl chloride in the presence of an lewis acid catalyst and an organic solvent to obtain the acylated product, reducing the acylated product to obtain the 4-chloralkylferrocene, treating the 4-chloroalkylferroce with a metal under Grignard reaction conditions to form its corresponding Grignard intermediate compound; and reacting with chloroalkylsilane in-situ to give the silylferrocene compound. The silylferrocene compound 4-(dimethylsilyl)butylferrocene can be prepared by the process of the invention.
US08664413B2	High-purity epoxy compound and method of producing thereof An epoxy compound of high-purity N,N,N′,N′-tetraglycidyl-3,4′-diaminodiphenyl ether is produced by: an addition reaction step of reacting 3,4′-diaminodiphenyl ether with epichlorohydrin in a polar protic solvent at 65 to 100° C. for 12 hours or longer to form N,N,N′,N′-tetrakis(3-chloro-2-hydroxypropyl)-3,4′-diaminodiphenyl ether; and a cyclization reaction step of reacting the N,N,N′,N′-tetrakis(3-chloro-2-hydroxypropyl)-3,4′-diaminodiphenyl ether with an alkali compound for dehydrochlorination.
US08664411B2	Tetrahydropyranochromene gamma secretase inhibitors Disclosed are novel gamma secretase inhibitors of the formula. Also disclosed are methods of inhibiting gamma-secretase, methods of treating neurodegenerative diseases, and methods of treating Alzheimer's Disease. Also disclosed are processes for preparing alkenes in one reaction step using a mixture of an aldehyde (or ketone) and an alkyl substituted with two electron withdrawing groups, and reacting the mixture with: (a) a sulfonyl halide (e.g., a sulfonyl chloride) and a basic tertiary amine, or, (b) a sulfonyl anhydride and a basic amine, or (c) an aryl-C(O)-halide and a basic tertiary amine, or (d) an aryl-C(O)—O—C(O)-aryl and a basic tertiary amine, or (e) an heteroaryl-C(O)-halide and a basic tertiary amine, or (f) a heteroaryl-C(O)—O—C(O)-heteroaryl and a basic tertiary amine.
US08664409B2	Process for the preparation of (poly) aminoalkylaminoacetamide derivatives of epipodophyllotoxin useful for their applications in therapeutics as anticancer agent The present invention relates to a new process for the preparation of (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin and salts thereof, characterized in that it comprises a step of peptide coupling of 4-amino-4′-demethylepipodophyllotoxin with an amine-containing reactant having protecting groups.
US08664408B2	Synthesis process, and crystalline form of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]proxy}benzamide hydrochloride and pharmaceutical compositions containing it Industrial synthesis process for, and crystalline form I of, the compound of formula (I): and also crystalline form I of the associated free base. Medicinal products containing the same which are useful in the treatment of disorders of the histaminergic system.
US08664403B2	Process The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]2-methylthiopropionate which is useful as a pharmaceutically active compound.
US08664392B2	Pyrazine derivatives for bioconjugation Provided are compounds and compositions of general Formula IX: E1-L-Ar—X-PA, that may be utilized in bioconjugation procedures, where Ar is a chromophore and PA is a functional group capable of being attached to any bioactive molecule of interest. The present invention provides Formulas I-III that are capable of being attached to a bioactive vector for the selective delivery of said photoactive pyrazine derivatives to a desired biological target.
US08664391B2	Amide compounds as boosters of antivirals The present invention relates to compounds of formula (I) that have CYP450 inhibiting properties and are useful as boosting agents when used with HIV treatments. These compounds are represented by formula including the salts and stereoisomeric forms thereof, wherein R1 is 5-thiazolyl or 3-pyridinyl; R2 is iso-butyl, 2,2-dimethylpropyl; 2-hydroxy-2-methyl-propyl or cyclohexylmethyl; R3 is phenyl optionally substituted with one or more halogens, trifluoromethyl, C1-6-alkyl or C1-6-alkoxy wherein optionally two of said alkoxy groups are be linked to each other to form a 5 or 6-membered ring; heteroaryl; C3-7cycloalkyl optionally substituted with one or more halogens; C1-6alkyl optionally substituted with heteroaryl; —O—CH2— (heteroaryl). As boosting agents they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered, or improve the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions comprising these compounds are also provided.
US08664389B2	Process for the preparation of lapatinib and it's pharmaceutically acceptable salts The present invention relates to an improved and novel process for the preparation of high purity crystalline base of Lapatinib of formula-(1) having chemical name N-{3-chloro-4-[(3-fluorobenzyloxy]phenyl}-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl]-2-furyl]-4-quin-azolinamine and its pharmaceutically acceptable salts. The present invention further relates to intermediates according to formula (8) and formula (9) used in this process.
US08664386B2	Methods for preparing anti-viral nucleotide analogs Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
US08664380B2	Heterocyclic compound and use thereof Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
US08664376B2	Retinoid-liposomes for enhancing modulation of HSP47 expression What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1—2 (SEQ ID NOS: 60 and 127), SERPINH1—45a (SEQ ID NOS: 98 and 165), and SERPINH1—51 (SEQ ID NOS: 101 and 168), and drug carrier comprising a mixture of a retinoid and a lipid vesicle, and methods of using these pharmaceutical compositions to treat a disease associated with hsp47 espresssion, including fibrosis.
US08664375B2	Interfering RNA delivery system and uses thereof The invention provides a delivery system comprising a cell penetrating peptide, a polyarginine peptide, and an interfering RNA molecule. The system can be used for delivering interfering RNA molecules into a cell in vivo or in vitro. Therapeutic uses for the delivery system are also provided.
US08664373B2	Method for producing sophorose lipid The present invention provides a low-cost, efficient method for producing a glycolipid biosurfactant, in particular, lactonic sophorose lipids. This method is characterized by culturing a microorganism capable of producing the biosurfactant under limited oxygen supply. The present invention enables preferential production of lactonic sophorose lipids and facilitates recovery of the lactonic sophorose lipids in a solid form. Further, the present invention enables production of high purity acidic sophorose lipids by hydrolyzing high purity lactonic sophorose lipids produced by the above method. The present invention also provides lactonic sophorose lipids that possess strong antibacterial and antifungal activities, and an antibacterial and/or antifungal agent containing the sophorose lipids.
US08664372B2	Process for producing 1,2-trans-glycoside compound In preparing a glycoside compound from (a) a furanose compound or pyranose compound, and (b) an alcohol compound, a process for preparing a glycoside compound in which glycosidic bond locates selectively trans form relative to C-2 hydroxyl group, the process comprising using a furanose compound wherein the hydroxyl at the 2-position may have a substituent protected with a group A, or a pyranose compound which may have a substituent wherein R2 and R3 are the same or different and are each alkyl having 1 to 4 carbon atoms or aryl having or not having a substituent, or R2 and R3 are combined to form alkylene having 2 to 4 carbon atoms (the alkylene may be substituted with alkyl having 1 to 4 carbon atoms, or may have intervening phenylene), and m and n are each an integer of 0 or 1.
US08664369B2	LH liquid formulations The invention relates to liquid pharmaceutical formulations of luteinizing hormone (LH) for single- or multi-dose administration.
US08664365B2	Antibodies to EphA3 The current invention relates to high-affinity antibodies to EphA3 that have reduced immunogenicity when administered to a human to treat diseases and method of using such antibodies.
US08664363B2	Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease Provided herein are chimeric and humanized versions of anti-CD22 mouse monoclonal antibody, HB22.7, which comprise human or humanized framework regions of the immunoglobulin heavy chain variable region (“VH”) and light chain variable region (“VK”). The FW regions may contain one or more backmutations in which a human FW residue is exchanged for the corresponding residue present in the parental mouse heavy or light chain. The human or humanized VH framework regions may comprise one or more of the following residues: a valine at position 24 of FW1, a glycine at position 49 of FW2, and an asparagine at position 73 of FW3, numbered according to Kabat. Further provided are pharmaceutical and immunotherapeutic compositions, and methods using anti-CD22 antibodies that preferably mediate human ADCC, CDC, and/or apoptosis for: the treatment of B cell diseases in humans, including B cell malignancies, autoimmune disease, GVHD, humoral rejection, and post-transplantation lymphoproliferative disorder.
US08664361B2	Soy products with reduced levels of sulfite, free radicals and methanethiol Soy products or compositions are treated with a food grade iodate compound or a cystine compound to reduce levels of methanethiol, sulfites and sulfite free-radicals, sulfate free radicals and other free radicals generated from sulfite free radicals in the soy products or compositions by 1% to 95%.
US08664355B2	Cell-free protein synthesis method with the use of linear template DNA and cell extract therefor It is provided a simple and efficient process for producing a large amount of protein in a cell-free protein synthesis system, through a continuous synthesis reaction over a long time using a linear DNA as a template. The continuous synthesis reaction is carried out for at least one hour with a cell-free protein synthesis system comprising an extract of Escherichia coli cells cultured at any temperature between 18° C. and 36° C., and a linear template DNA encoding the protein. The continuous protein synthesis system is preferably a dialysis system or a continuous flow system. The cell-free protein synthesis system by dialysis system comprises an internal dialysate comprising the extract and the linear template DNA, an external dialysate comprising a substrate solution for protein synthesis, and a dialysis membrane through which the substrate can be transferred.
US08664349B2	Polycarbonate compositions having improved optical properties The present invention relates to polycarbonate compositions and copolycarbonate compositions having improved optical properties, and to their production and their use for the production of shaped parts, and to shaped parts which can thereby be obtained, the compositions containing a polycarbonate or copolycarbonate which comprises bisphenol-A and at least one pair of a phosphorus compound having the oxidation number +3 and a phosphorus compound having the oxidation number +5, and the phosphorus compound having the oxidation state +5 in a pair respectively corresponding to the oxidized form of the phosphorus compound having the oxidation state +3 and the amount of more highly oxidized compound contained being less than that of the compound with the lower oxidation number.
US08664346B2	Process for preparing organopolysiloxanes A targeted molecular weight of an organopolysiloxane is obtained in a two stage hydrolysis by hydrolyzing a chlorosilane with from 0.002 to 0.6 mol of water in a first step in the presence of alcohol, in which the pressure and/or temperature are adjusted such that following further hydrolysis in a second step, the targeted molecular weight is obtained.
US08664345B2	Process for the preparation of a catalyst composition for dimerization, codimerization and oligomerization of olefins This invention describes a process for the preparation of a catalytic composition that can be used for oligomerization, codimerization, or polymerization of olefins. This invention also describes the catalytic composition that can be obtained by said process for the preparation and its use for oligomerization, codimerization, or polymerization of olefins.
US08664341B2	Vinylbenzyl ethers of polycyclopentadiene polyphenol Embodiments include vinylbenzyl ethers of polycyclopentadiene polyphenol that can be obtained by reacting a polycyclopentadiene polyphenol with a vinylbenzyl halide. Embodiments also include thermosettable compositions including the vinylbenzyl ethers of a polycyclopentadiene polyphenol and products obtained by curing the thermosettable compositions. Formula (I).
US08664339B2	Organic semiconducting polymers Disclosed are new organic semiconducting polymers. The polymers disclosed herein can exhibit high carrier mobility and/or efficient light absorption/emission characteristics, and can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.
US08664338B2	Processability improver for foam molding and vinyl chloride resin composition containing same An object of the present invention is to provide a foaming vinyl chloride resin composition having excellent foaming properties and providing a foam molded product with an excellent appearance by enhancing the melt strength of the vinyl chloride resin composition. A processability improver for foam molding according to the present invention includes a (meth)acrylic polymer powder with a weight average molecular weight of 2,000,000 to 7,000,000, wherein the (meth)acrylic polymer powder includes 1 to 20% by weight of a (meth)acrylic polymer (A) with a weight average molecular weight of 10,000 to 300,000, and 80 to 99% by weight of a (meth)acrylic polymer (B) with a weight average molecular weight of 2,000,000 to 7,000,000.
US08664337B2	Thick blown films The present invention is a film having a thickness greater than 100 microns comprising from 10 to 100 percent by weight of a polyethylene polymer made by the process of a) selecting a target polyethylene resin having a density, as determined according to ASTM D792, in the range of from 0.90 g/cm3 to 0.955 g/cm3, and a melt index, as determined according to ASTM D1238(2.16 kg, 190 C), in the range of from 0.01 g/10 min to 10 g/10 min; b) reacting said target polyethylene with an alkoxy amine derivative in an amount less than 900 parts derivative per million parts by weight of total polyethylene resin under conditions sufficient to increase the melt strength of the target polyethylene resin; and c) forming a thick film from the modified target resin. The present films include those which can achieve similar processability as those containing unmodified linear polyethylene despite having at least 10% less LDPE resins in the formulation.
US08664335B2	Thermally crosslinked polymeric compositions and methods of making the same The various embodiments of the present disclosure relate generally to thermally crosslinked polymeric compositions and methods of making thermally crosslinked polymeric compositions. An embodiment of the present invention comprises a composition comprising: a first polymer comprising a first repeat unit, the first repeat unit comprising a carboxyl group, wherein the first polymer crosslinks to a second polymer formed from a second repeat unit, and wherein the first polymer crosslinks to the second polymer without formation of an ester group.
US08664333B2	Acetoacetic ester group-containing polyvinyl alcohol-based resin, resin composition, and uses thereof An object of the present invention is to provide a new acetoacetic ester group-containing polyvinyl alcohol-based resin that contains less amount of water-insoluble matter and is excellent in transparency and viscosity stability when converted into an aqueous solution, and that realizes excellent water resistance by combined use of a crosslinking agent. The invention provides an acetoacetic ester group-containing polyvinyl alcohol-based resin containing a structural unit represented by the general formula (1): wherein at least one of R1 and R2 represents an acetoacetyl group, R3, R4, R5, R6, R7 and R8 each independently represents an arbitrary substituent, and X represents a single bond or an arbitrary bonding chain.
US08664327B2	Coating composition and method for forming coating film The present invention provides a coating composition that is excellent in application workability, and that can form a cured coating film excellent in coating film performances such as scratch resistance, acid resistance, stain resistance, finished appearance, sagging resistance, etc. Specifically, the present invention provides a coating composition comprising an acrylic resin (A), a polyisocyanate compound (B) and a specific non-aqueous dispersion-type acrylic resin (C), wherein: the acrylic resin (A) is obtainable by copolymerization of a specific secondary hydroxyl group-containing monomer (a-1), a secondary hydroxyl group-containing polyoxyalkylene mono(meth)acrylate monomer (a-2), an isobornyl (meth)acrylate monomer (a-3) and at least one other copolymerizable unsaturated monomer (a-4), the unsaturated monomer (a-1) being used in an amount (mass) greater than that of the monomer (a-2).
US08664323B2	Fluorinated composition, method of coating the composition, and article thereby A fluorinated composition includes: a polyfluoropolyether silane represented by the formula: RfaO(CF(CF3)CF2O)pCF(CF3)CH2OZ1Si(Y1)3; and a polyfluoropolyether silane represented by the formula: Rfb[R5CH2OZ2Si(Y2)3]2 Rfa represents a perfluoroalkyl group having from 1 to 12 carbon atoms, optionally substituted with at least one catenated oxygen atom or —NR8— group, wherein R8 represents a perfluoroalkyl group; Z1 represents —R1SR2—, —R1S(═O)R2—, or —R1S(═O)2R2, wherein R1 and R2 independently represent alkylene groups having from 1 to 12 carbon atoms; each Y1 independently represents a hydrolyzable group; and p is a number in a range of from 3 to 50; Z2 independently represents —R3SR4—, —R3S(═O)R4—, or —R3S(═O)2R4, wherein R3 and R4 independently represent alkylene groups having from 1 to 12 carbon atoms; Y2 independently represents a hydrolyzable group; Rfb represents a perfluoroalkylene group having at least 3 carbon atoms, optionally substituted with at least one catenated oxygen atom or —NR6— group, wherein R6 represents a perfluoroalkyl group; R5 independently represents a covalent bond, or —(OR7)b—, and wherein R7 independently represents a branched perfluoroalkylene group, and b independently represents a number greater than or equal to one.
US08664321B2	Process for the continuous preparation of high viscosity silicon compositions Organopolysiloxane compositions having a 25° C. viscosity of at least 500 Pa·s., are continuously prepared by mixing and kneading organopolysiloxanes and fillers in a first process stage, in a kneading cascade having at least two kneading chambers arranged in series each containing two kneading tools on parallel axes, capable of being driven in corotating or counterrotating directions, the chambers connected to one another by means of openings through which material can pass in a direction transverse to the axes of the kneading tools, the first kneading chamber having a feed opening and the last kneading chamber having a discharge opening, to give raw mixtures and kneading and degassing the raw mixtures, in a second process stage at from 100° C. to 250° C. in a continuously operated double trough kneader having a discharge screw.
US08664314B2	Mixtures of N-alkanols and their use Use of mixtures, comprising a total of at least 50% by weight of n-alkanols, selected from n-C24-C34 alkanols, as additive in the processing of thermoplastic polymers.
US08664309B2	Optical film and process for its production To provide an optical film wherein deterioration of a diimonium compound in an adhesive layer is prevented, and a process for its production. An optical film comprising a base film and an adhesive layer which is formed on the base film and has a massive material dispersed in an adhesive, wherein the massive material contains a diimonium compound represented by the following formula (1) and has a melting point of at least 200° C.: wherein R1 to R8 represent each independently an unsubstituted or substituted, same or different, C1-6 aliphatic hydrocarbon group, provided that from 4.9 to 8 groups among R1 to R8 are a C1-3 aliphatic hydrocarbon group (in which some of hydrogen atoms may be substituted by halogen atoms), and X− represents (R9SO2)3C− wherein R9 represents a C1-4 aliphatic hydrocarbon group which is unsubstituted or substituted by a halogen atom.
US08664308B2	Compatibilizers for producing nanocomposites, microcomposites and polymer blends and process for obtaining them The present invention relates to compatibilizers to be used for obtaining materials called polyolefin nanocomposites, microcomposites and polymer blends, and it includes the process for obtaining such compatibilizers. Such compatibilizers are obtained from the monomers of the organic compounds itaconic acid (ITA) or its monooctadecyl itaconate (MODIT) derivative. The compatibilizers are polyolefins grafted with those monomers, which are characterized by having functional groups with a hydrophilic character and a polymer backbone with a hydrophobic character. The compatibilizers of this invention are characterized by having controlled degrees of grafting of these monomers, and they can be used optimally in various applications. It also relates to the process for obtaining such compatibilizers.
US08664306B2	Liquid hardening Curing agents for air-drying alkyd-based resins, coatings, such as paint, varnish or wood stain, inks and linoleum floor coverings, based on an iron/manganese complex containing tetradentate, pentadentate or hexadentate nitrogen donor ligands are disclosed.
US08664302B2	Process of polymer modified asphalt preparation A process of preparing a polymer modified asphalt (PMA) comprising mixing a predetermined amount of a polymer-asphalt master batch with a predetermined amount of an asphalt-cross linking agent blend. The polymer-asphalt master batch comprises at least one polymer and a first asphalt. The asphalt-cross linking agent blend comprises a second asphalt and at least one cross linking agent. A predetermined amount of the polymer-asphalt master batch is blended with a predetermined amount of the asphalt-cross linking agent blend to form a PMA blend. Mixing of the PMA blend is performed without substantial delay following blending of the polymer-asphalt master batch with the asphalt-cross linking agent blend.
US08664300B2	Renewable and cost-effective fillers for polymeric materials Polymer composites are provided, and more particularly, polymer composites of ground date pits disposed in a polymer matrix. The composites can be formed by a process of preparing reinforced polymer composites having a fibril melt fracture surface, including blending a mixture of date pit particulate with a thermoplastic polymer; melting the mixture; and forcing the melt through a die to produce the polymer composite having a fibril containing surface.
US08664296B2	Ink set for ink jet recording and ink jet recording method An ink set for ink jet recording including an ink composition containing a coloring material, and a polymer particle including 65 mass % or more of a constituent unit derived from a methacrylic acid derivative, and a treating liquid which forms an aggregate when contacted with the ink composition, and an ink jet recording method using the same are provided.
US08664291B2	Ultraviolet-curable ink jet ink composition Provided is an ultraviolet-curable ink jet ink composition with excellent curability and storage stability, the composition containing a monomer A represented by Formula (I): CH2═CR1—COOR2—O—CH═CH—R3 (wherein R1 represents a hydrogen atom or a methyl group, R2 represents a C2-C20 divalent organic residue, and R3 represents a hydrogen atom or a C1-C11 monovalent organic residue); a (meth)acrylated amine compound; a hindered amine compound other than the (meth)acrylated amine compound; and a photopolymerization initiator.
US08664288B2	O-imino-iso-urea compounds and polymerizable compositions thereof The invention relates to the use of O-imino-iso-urea compounds as source of radicals to polymerizable compositions comprising these O-imino-iso-urea and to new O-imino-iso-urea compounds. The O-lmino-isoureas compounds are compounds of the Formula (I), wherein n is 1, 2, 3 or 4, R100 and R101 are independently H, C1-18 alkyl, C3-C12cycloalkyl, C6-C14aryl, C1-C14heteroaryl, C7-C15aralkyl, C2-C14heteroaralkyl, Cyano, or R100 and R101 form together with the carbon to which they are attached a mono or polycyclic C3-C18 carbocyclic or C1-C18 heterocyclic ring; R102 and R103 are independently C1-C18alkyl, C3-C12cycloalkyl, C6-C14aryl, C6-C14aryl once or more than once substituted by C1-C18alkyl; C7-C15aralkyl, (CH3)3Si—; or R102 and R103 are C1-C18alkyl, C3-C12cycloalkyl, C6-C14aryl, C7-C15aralkyl or R102 and R103 are C1-C18alkyl, C3-C12cycloalkyl which are interrupted or substituted by O or by N containing groups selected from C1-C18alkylamino, bis(C1-C18alkyl)amino or tris(C1-C18alkyl)ammonium; R104 if n is 1 is H, C1-C18alkyl, C3-C12cycloalkyl, C7-C14aralkyl, C6-C14aryl or acyl selected from the group consisting of the following acyls —C(═O)—H, —C(═O)—C1-C18alkyl, —C(═O)—C2-d18alkenyl, —C(═O)—C6-C14aryl, —C(═O)—C2-C18alkenyl-C6-C14aryl, —C(═O)—O—C1C18alkyl, —C(═O)—O—C6-C14aryl, —C(═O)—NH—C1-C18alkyl, —C(═O)—NH—C6-C14aryl and —C(═O)—N(C1C18alkyl)2; or R102 and R104 if n is 1 form together with the nitrogen atom to which they are attached a 5 to 12 membered ring which may contain additional heteroatoms, R104 if n is more than 1 is di-, tri-, tetra-C1-C18alkylidene, diacyls, triacyls or tetraacyls and salts thereof.
US08664286B2	Vibration damping composition To provide a vibration damping composition: excellent in vibration damping property and thermal drying property in a wide temperature range; and sufficiently suppressing sagging of a vibration damping coating film on the vertical surface; and therefore useful for vibration damping materials of various structures.A vibration damping composition comprising an emulsion for vibration damping materials, a foaming agent, and an inorganic pigment, wherein the emulsion for vibration damping materials comprises a particle having a core part formed from an acrylic copolymer (A) and a shell part formed from an acrylic copolymer (B), and at least one of the acrylic copolymers (A) and (B) is prepared by copolymerizing a monomer component comprising methacrylic acid.
US08664285B2	Composite material The invention relates to composite materials, containing (i) a nanoporous polymer foam, which can be obtained by reacting one or more epoxy resins with one or more amphiphilic epoxy resin hardeners in water in a phase inversion polymerization process, and (ii) one or more inorganic fillers and/or inorganic fibers, with the stipulation that hollow glass balls are excluded as fillers. Said composite materials are suitable as heat-insulating materials.
US08664284B2	Depolymerization of polymers A method of depolymerizing formulated rubbers and polymer solids is described. The method utilizes a solvent at or above the solvent's critical pressure and critical temperature with a low ratio of solvent to the solid material. The resulting depolymerized material in either substantially solid or highly viscous liquid form can be repolymerized with the addition of more monomer.
US08664280B2	Bioresorable polymer matrices and methods of making and using the same A kit for forming a bioerodible composition is provided with a first aliquot portion of a reaction mixture having an aldehydic polymer solution, and a second aliquot portion of a reaction mixture having solids which include a cross-linking hydrazide. When mixed, the first and second aliquot portions of the reaction mixture react at a pH of 4 to 6 to form a solidified bioerodible composition within about 1 to about 10 minutes, to form a hydrazide cross-linked aldehydic polymer matrix. The bioerodable composition may be usefully employed to seal and/or treat wounds (e.g., a surgical incision).
US08664274B2	Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pinchinde, and VSV), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).
US08664270B2	Clog resistant insect control formulations having terminal diyne acetylenic hydrocarbon and pyrethrin Disclosed are pyrethrin-based insect control compositions which have been formulated to reduce wick clogging. An acetylenic hydrocarbon having at least two terminal alkyne groups, such as 1,8-nonadiyne, together with an antioxidant such as dilauryl thiodipropionate, are used to reduce clogging caused by components of pyrethrum extract.
US08664264B2	Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof The present invention provides an antiproliferative compound having a structural formula where X and Y independently are oxygen, nitrogen or sulfur; R1 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, carboxylic acid, carboxylate, carboxamide, ester, thioamide, thiolacid, thiolester, saccharide, alkoxy-linked saccharide, amine, sulfonate, sulfate, phosphate, alcohol, ethers or nitriles; R2 and R3 are hydrogen or R4; R4 is methyl, benzyl carboxylic acid, benzyl carboxylate, benzyl carboxamide, benzylester, saccharide or amine; and R5 is alkenyl; where when Y is nitrogen, said nitrogen is substituted with R6, wherein R6 is hydrogen or methyl. Also provided are methods for treating a cell proliferative disease and for inducing apoptosis in a cell comprising administering this compound is also provided.
US08664260B2	De novo synthesis of bacteriochlorins A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
US08664259B2	Oil-based suspension concentrates New, oil-based suspension concentrates composed of at least one room-temperature-solid compound of the formula (I′), at least one penetrant, at least one vegetable oil, at least one nonionic surfactant and/or at least one anionic surfactant, and optionally one or more additives from the groups of the emulsifiers, foam inhibitors, preservatives, antioxidants, colorants and/or inert filler materials, a process for producing these suspension concentrates, and their use for applying the active substances comprised.
US08664258B2	Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto The present invention pertains to certain compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggreagation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, blood clot formation, asthma or symptoms thereof, agitation or a symptom thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like. The present invention also relates to the methods for the treatment of 5-HT2A serotonin receptor associated disorders in combination with other pharmaceutical agents administered separately or together.
US08664255B2	Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the enzyme. The compounds may be phenyl- naphthyl-, or thienyl-substituted diketo acids and carboxylate derivatives thereof. Also provided are methods of treating tuberculosis or other pathophysiological conditions associated with a malate synthase enzyme with the inhibitory compounds and methods of in silico design of the inhibitory compounds. In addition, the present invention provides the inhibitory compounds designed by this method. Furthermore, three-dimensional X-ray crystal structures of the Mycobacterial malate synthase complexed with the inhibitory compounds are provided. Further still a method for stabilizing an aromatic or heteroaromatic diketo acid or its prodrug or close analog in solution by derivatizing at least the ortho position on the aromatic ring is provided.
US08664253B2	Imidazole derivatives useful as modulators of FAAH and as FAAH imaging agents The present invention is directed to certain Inidazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.
US08664251B1	Ryanodine receptor inhibitors for treatment of T-cell mediated disorders This invention relates to methods of treating T-cell mediated diseases or disorders in human or animal subjects, such as autoimmune diseases and chronic graft versus host disease in humans and animals. In particular, the methods comprise administering to the human or animal patient a pharmaceutical composition comprising a ryanodine receptor inhibitor.
US08664250B1	Synergistic combination of fungicides to protect wood and wood-based products and wood treated by such combination as well as methods of making the same A wood treatment composition having a synergistic combination of fungicides which may include two or more compounds. These combinations are shown to be especially effective in providing resistance to decay, mold and mildew when wood is treated with these combinations. Also provided is wood treated by these combinations, and a method of treatment for composite wood.
US08664249B2	Tetrasubstituted benzenes Tetrasubstituted benzenes that act as modulators of gamma secretase and their use in the treatment of one or more symptoms of treating neurodegenerative disorders, e.g., Alzheimer's disease, are described.
US08664248B2	Derivatives of pyridoxine for inhibiting HIV integrase The present invention relates to methods of treating hepatitis C infection, HIV infection, AIDS, or AIDS-related complex, or inhibiting HIV replication by administering a compound of Formula I wherein: X is H or OH; Y is H or OH; R1 is H or halogen (F, Cl, Br, I); R2 is H or halogen (F, Cl, Br, I); R3 is H, C1-6 alkyl, C1-6 fluoroalkyl, or benzyl; R4 is H, C1-6 alkyl, or benzyl; and R5 is H or C1-6 alkyl; or pharmaceutically acceptable salts thereof, to a mammal.
US08664246B2	Substituted pyridines, and use thereof as GSK3 inhibitors The invention relates to substituted pyridines and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of haematological disorders, preferably of leukopenia and neutropenia.
US08664244B2	Compounds as c-Met kinase inhibitors The present invention relates to compounds, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with the inhibition of the protein tyrosine kinase activity of growth factor receptors such as c-Met, thereby making them useful as anticancer agents, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
US08664243B2	Sulfonamide compound and crystal thereof (S)-1-(4-Chloro-5-isoquinolinesulfonyl)-3-(methylamino)pyrrolidine monohydrochloride and a crystal thereof, and a crystal of the aforementioned monohydrochloride having a major peak or peaks at one or more positions selected from the group consisting of positions where 2θs are about 13.9°, 21.5°, 21.7°, 22.4°, 22.8°, 24.5° and 35.0° in a powder X-ray diffraction spectrum, which have excellent properties as active ingredient of a medicament for prophylactic and/or therapeutic treatment of glaucoma and the like.
US08664240B2	R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial Disclosed herein are R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial. Because the R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl) -1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt is more soluble and less toxic and has less side effects as an antimicrobial agent than hydrochloride and the other salts (D-aspartate and phosphate) conventionally used, the salt may be useful for oral and injectable administration.
US08664234B2	Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators The present invention is directed to dihydrobenzoquinazilinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
US08664233B2	Substituted 5H-pyrimido[5,4-B]indoles, method for the production thereof and use thereof for treating non-solid malignant tumors of the blood-producing system The invention relates to compounds of general formula 1 to processes for the production thereof, to pharmaceutical preparations containing said compounds and/or physiologically compatible salts and/or solvates which can be produced therefrom as well as to the pharmaceutical use of said compounds, the salts or solvates thereof as inductors of apoptosis in the case of non-solid malignant tumors of the hematopoietic system, in particular in the case of leukemias and lymphomas, more particularly in the case of leukemic B lymphocytes.
US08664231B2	Concentrated methotrexate solutions Concentrated methotrexate solutions are described which are suitable for the use of an active substance in the production of a parenterally administered medicament for the treatment of inflammatory autoimmune diseases. The methotrexate is added to a pharmaceutically acceptable solvent at a concentration of more than 30 mg/ml. The invention also relates to a ready-made syringe and a carpule containing such a pharmaceutical solution formulation, as well as a pen injector comprising such a carpule and/or a ready-made syringe.
US08664225B2	1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition The use of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine in the treatment of pain and residual symptoms in depression is provided.
US08664218B2	Pharmaceutical compounds The invention provides a compound of the formula (1): or a salt, solvate, N-oxide or tautomer thereof.
US08664211B2	Modified amino acid for the inhibition of platelet aggregation A method of inhibiting blood platelet aggregation in a mammal is provided. The method comprises the administration of a platelet aggregation inhibiting amount of a modified amino acid or pharmaceutically acceptable salt thereof.
US08664206B2	Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 Compounds of formula I are provided where X1, X2, and X3 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
US08664203B2	Thiazole derivatives and their use as P2Y12 receptor antagonists The present invention relates to thiazole derivatives of formula I and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
US08664199B2	Method and system for reversal of interactions between hydrophobically modified biopolymers and vesicles or cell membranes A method for reversing gelation of hydrophobically modified biopolymer attached to vesicle or cell membranes. The gelation of hydrophobically modified biopolymer attached to vesicles or cell membranes is reversed by application of a supramolecule, such as cyclodextrin, to the gelled composition. The supramolecule disrupts the interactions between the hydrophobically modified biopolymer and the vesicle or cell membrane, without affecting the structure of the membrane or the hydrophobically modified polymer to which the hydrophobic substituents are attached. A kit for treating wounds that includes a hydrophobically modified biopolymer and a supramolecule. The hydrophobically modified biopolymer is used to stop bleeding and the supramolecule is used to remove the hydrophobically modified biopolymer.
US08664194B2	Method for producing a protein of interest in a primate The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
US08664192B2	Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer Methods of reducing spontaneous mutation rate of a cell in a subject in need thereof by reducing endogenous levels of miR-155 are described.
US08664191B2	Use of two microRNA moleculars in lung cancer prognosis and medicine preparation The present invention relates to use of two microRNAs in detection of lung cancer prognosis and in medicine preparation. Particularly, the invention relates to a composition comprising two small RNA molecules microRNA-150 and microRNA-886-3p, a device comprising the composition used in detection of lung cancer prognosis and in preparation of medicaments for inhibiting mammal and human lung cancer metastasis. Specifically, the expression levels of microRNA-150 and microRNA-886-3p can be used as the prognostic criteria of lung cancer prognosis, wherein high expression level of the gene combination indicates favorable therapeutic effect. The invention also relates to a device detecting the expression levels of microRNA-150 and microRNA-886-3p in mammalian and human lung cancer and a method for detecting the expression levels of microRNA-150 and microRNA-886-3p in samples.
US08664189B2	RNA interference in skin indications The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal applications.
US08664184B2	Therapy with Clostridium perfringens enterotoxin to treat ovarian and uterine cancer The invention discloses high levels of receptors for Clostridium perfringens enterotoxin (CPE) have been found in ovarian cancer and uterine cancer tissue samples. In addition, successful in vivo treatment of a mouse model of ovarian cancer with intraperitoneal injection of CPE is disclosed. High levels of Ep-CAM protein is also disclosed in ovarian cancer tissue samples. Thus, the invention provides a method of treating ovarian cancer and uterine cancer by administering CPE. The invention also provides a method of treating cancer in a mammal involving intraperitoneal administration of CPE, where at least some cancerous cells are located in or adjacent to the peritoneal cavity of the mammal. The invention also provides a method of treating ovarian cancer involving administering an anti-Ep-CAM antibody. The invention also provides a method of treating cancers expressing claudin-3 or claudin-4 by administering an antibody against claudin-3 and/or an antibody against claudin-4. The invention also provides a method of protecting a mammal from CPE toxicity involving administering a protective agent that binds to claudin-3 and/or claudin-4 and inhibits CPE binding to claudin-3 and/or claudin-4.
US08664176B2	Treatment for age-related macular degeneration and other diseases of the eye A method is disclosed for treating diseases or disorders of the eye involving undesired neovascularization by administration of a complement inhibitory protein such as soluble complement receptor type I (sCR1). The present invention relates to the direct treatment of macular degeneration, particularly age-related macular degeneration (AMD), by administering a complement inhibitory protein intraocularly or systemically.
US08664174B2	Composition comprising microcapsules A liquid composition having a microcapsule, the microcapsule having an aldehyde-containing resin, and one or more formaldehyde scavenger which reacts with formaldehyde to achieve more than about 60% reaction completeness in about 15 minutes time at pH 8 and at about 21° C. A liquid composition having a microcapsule, the microcapsule having an aldehyde-containing resin, one or more sulfur-based formaldehyde scavenger and optionally a non-sulfur-based formaldehyde scavenger.
US08664173B2	Premoistened cleaning disposable substrate for leather and method of preserving a leather surface by contacting said surface with said substrate The present invention is directed to a premoistened, disposable, cleaning substrate to improve dirt pick-up and to retard redeposition of the dirt back onto the cleaned leather surface. The said substrate is incorporated therein with a cleaning composition to improve cleaning and impart protection and/or preservation of the leather surface or article. The said substrate is further incorporated therein with UV absorbers to further protect the leather surface, improve appearance and durability. The impregnated substrate can be employed to clean leather surfaces such as furniture, clothing, shoes, belts, automobile upholstery and the like. In addition, a method of preserving a leather surface or article by contacting said surface with said substrate is disclosed.
US08664172B2	Self-sticking disintegrating block for toilet or urinal A self-sticking disintegrating cleansing block to be attached directly to a wall of a toilet bowl or urinal, above the water-line and in the stream of flush water, by pressing the cleansing block to the wall. The cleaning block includes 25% to 99% of a solid surfactant, and 1% to 25% of a liquid component. The cleansing block may include a substrate removably attached to a surface of the cleansing block. In use, the substrate is removed from the cleansing block and the exposed surface of the cleansing block is pressed to a surface in a position above any waterline that is contacted by a rinse liquid that disintegrates the cleansing block. Rinse liquid is then allowed to contact the cleansing block such that an amount of the cleansing block is mixed with rinse fluid to clean the surface or a liquid reservoir adjacent the surface.
US08664170B2	Low temperature performance lubricating oil detergents and method of making the same The present invention is directed to a method for preparing an unsulfurized, carboxylate-containing additive for lubricating oils and the product produced by said method, wherein said method comprises a) neutralization of a mixture of at least two alkyl phenols using an alkaline earth base in the presence of a promoter, to produce a mixture of alkyl phenates, wherein the mixture of at least two alkyl phenols comprises at least a first alkyl phenol wherein the alkyl group is derived from an isomerized alpha olefin and a second alkyl phenol wherein the alkyl group is derived from a branched chain olefin; (b) carboxylation of the mixture of alkyl phenates obtained in step (a) using carbon dioxide under carboxylation conditions sufficient to convert at least 20 mole % of the starting alkyl phenols to alkyl salicylate; and (c) removal of at least about 10% of the starting mixture of at least two alkyl phenols from the product produced in step (b) to produce said additive.
US08664169B2	Lubricating compositions for transmissions The present disclosure relates to lubricating compositions for transmissions, in particular for gear boxes, and to the use thereof for limiting the fuel consumption of motor vehicles. The compositions according to the disclosure are suitable for all types of vehicles, especially light vehicles, and are particularly suitable for hybrid engine vehicles.
US08664168B2	Method of using composites in the treatment of wells A well treatment composite comprising a well treatment agent adsorbed onto a water-insoluble adsorbent may be prepared by precipitating the well treatment agent, in the presence of a metal salt, from a liquid while the well treatment agent is being adsorbed onto the water-insoluble adsorbent. After a treatment fluid containing the composite is introduced into a well or a subterranean formation, the well treatment agent is slowly released from the composite. The composite permits a continuous supply of the well treatment agent into a targeted area and is particularly effective in high pH treatment fluids.
US08664163B2	High temperature superconductive films and methods of making them Described is an article including a sapphire substrate carrying a superconductive layer of a compound of the formula YBa2Cu3O7-x (YBCO), the layer having surface area of at least 10 cm2, and critical current of at least 100 A/cm width at a temperature of 77K or higher. In one exemplary embodiment, the thickness of the superconductive layer is between 10 nm and 50 nm. In another exemplary embodiment, the thickness of the superconductive layer is more than 600 nm. In preferred embodiment, an YSZ layer and a non-superconductive YBCO layer separate between the superconductive layer and the substrate.
US08664162B2	Method for application of pesticides and plant growth regulators and nutrients to plants The present invention provides methods for applying active ingredients including pesticides, plant growth regulators and plant nutrients to plants by applying formulations comprising the active ingredients and a solvent to the soil around a plant.
US08664161B2	Method for increasing long-term storage of cut flowers A composition and method increases storage stability of cut flowers, particularly roses. A liquid composition is applied onto the cut flowers, and then it is converted to a protective polymeric film of a thickness of from about 0.001 to about 0.5 mm.
US08664160B2	Fungicidal mixtures Fungicidal mixtures, comprising (1) triticonazole of the formula I or salts or adducts thereof and (2) pyraclostrobin of the formula II and (3) at least one acylalanine selected from the group consisting of metalaxyl-M of the formula III and (4) kiralaxyl of the formula IV in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compounds I to III or I, II and IV and the use of the compounds I to III or I, II and IV for preparing such mixtures, and also compositions comprising such mixtures.
US08664159B2	Thermal transfer image-receiving sheets The present invention relates to a thermal transfer image-receiving sheet including a dye receiving layer formed of a resin composition for thermal transfer image-receiving sheets, wherein said resin composition includes a resin composition (A) containing a graft polymer (A0) which contains a main chain segment (A1) formed of a polyester resin obtained by polycondensing an alcohol component containing an alkyleneoxide adduct of 2,2-bis(4-hydroxyphenyl)propane in an amount of 50 mol % or more with a carboxylic acid component, and a side chain segment (A2) formed of an addition polymer-based resin, and has a glass transition temperature of 50° C. or higher; and a resin composition (B) containing a resin (B0) and having a glass transition temperature lower by from 10 to 80° C. than the glass transition temperature of the resin composition (A), and to a process for producing the thermal transfer image-receiving sheet.
US08664155B2	Carbon material for electric double layer capacitor and process for producing the carbon material The present invention provides a process for producing an activated carbon having a small average particle diameter, a uniform particle size and a relatively large specific surface area suitable for an electric double layer capacitor electrode, in an easy and cost effective manner. The process comprises calcining an easily graphitizable carbon material such as petroleum coke or coal coke, used as the raw material under an oxidizing gas atmosphere, adjusting the particle size of the carbon material, and then activating the carbon material. The use of the activated carbon produced by the process of the present invention in an electrode can provide an electric double layer capacitor having a large capacitance per unit volume.
US08664154B2	Methods of making and using activated carbon-containing coated substrates and the products made therefrom The present disclosure relates to methods of making and using activated carbon-containing coated substrates, and products made therefrom.
US08664150B2	Methods of producing adsorption media including a metal oxide Methods of producing a metal oxide are disclosed. The method comprises dissolving a metal salt in a reaction solvent to form a metal salt/reaction solvent solution. The metal salt is converted to a metal oxide and a caustic solution is added to the metal oxide/reaction solvent solution to adjust the pH of the metal oxide/reaction solvent solution to less than approximately 7.0. The metal oxide is precipitated and recovered. A method of producing adsorption media including the metal oxide is also disclosed, as is a precursor of an active component including particles of a metal oxide.
US08664147B2	Method for preparation of bimetallic compositions of cobalt and palladium on an inert material support and compositions obtainable by the same This invention concerns a procedure for the formation of a bimetallic composition by means of the subsequent depositing of Co(0) and Pd(0) on an inert support, a composition obtained by means of said procedure and the use of said bimetallic composition as a catalyst. Another aspect of this invention is a catalytic device that includes said bimetallic composition.
US08664146B2	Catalyst composition preparation and use A bulk metal oxide catalyst composition of the general formula (X)b(M)c(Z)d(O)e (I) wherein X represents at least one non-noble Group VIII metal; M represents at least one non-noble Group VIb metal; Z represents one or more elements selected from aluminum, silicon, magnesium, titanium, zirconium, boron, and zinc; one of b and c is the integer 1; and d and e and the other of b and c each are a number greater than 0 such that the molar ratio of b:c is in the range of from 0.5:1 to 5:1, the molar ratio of d:c is in the range of from 0.2:1 to 50:1, and the molar ratio of e:c is in the range of from 3.7:1 to 108:1; is prepared by controlled (co)precipitation of component metal compounds, refractory oxide material, and alkali compound in protic liquid. Resulting compositions find use in hydrotreatment processes involving particularly hydrodesulphurization and hydrodenitrification.
US08664145B2	Methods of preparing an aromatization catalyst A method of preparing a fresh catalyst comprising impregnating a metal into a catalyst support to produce an impregnated catalyst, dispersing the metal in the impregnated catalyst to produce an impregnated, dispersed catalyst, contacting the impregnated, dispersed catalyst with an activating composition to produce an impregnated, dispersed, activated catalyst, and thermally treating the impregnated, dispersed, activated catalyst to produce a fresh catalyst wherein the activating composition is in the liquid phase.
US08664142B2	Manufacturing method of solid catalyst for propylene polymerization Disclosed is a method for preparing a solid catalyst for propylene polymerization, specifically to a method for preparing a solid catalyst for propylene polymerization which can produce a polypropylene having high melt flow rate, a wide molecular distribution and excellent stereoregularity with a high production yield.
US08664141B2	Catalyst for cleaning up nitrogen oxides and a method for producing same Provided is a silver-supported alumina catalyst for reducing nitrogen oxides using ethanol, which has the drawbacks of the conventional silver-supported alumina catalysts improved, has high performance, is not likely to deteriorate over time, and has excellent initial performance and durability.A catalyst for purifying nitrogen oxides, which purifies nitrogen oxides in exhaust gas using an alcohol as a reducing agent, and contains alumina, aluminum sulfate and silver as main components.
US08664138B2	Regenerating method for activated alumina used in regenerating working fluid of hydrogen peroxide A regenerating method for activated alumina used in regenerating working fluid of hydrogen peroxide comprises the following steps: adding deactivated alumina discharged from a regenerating bed for working fluid of hydrogen peroxide with fire resistant alumina into a reactor through the top of the reactor and settling by gravity, oxidizing atmosphere entering into the reactor from the bottom of the reactor and running upwardly, discharging regenerated alumina and fire resistant alumina through the discharging device on the bottom of the reactor, discharging exit gas through the discharge port on the top of the reactor, the reaction temperature ranging from 360-800° C., the residence time of solid feed in the reactor ranging from 3-15 h. The method is economic, environment-protective, safe, and low-costly. The regenerated alumina will not poison palladium catalyst.
US08664136B2	Indium oxide sintered compact and sputtering target A sintered body includes an indium oxide crystal, and an oxide solid-dissolved in the indium oxide crystal, the oxide being oxide of one or more metals selected from the group consisting of aluminum and scandium, the sintered body having an atomic ratio “(total of the one or more metals)/(total of the one or more metals and indium)×100)” of 0.001% or more and less than 45%.
US08664135B2	Crucible body and method of forming same An article including a monolithic crucible body comprising silicon oxynitride (SixNyO, wherein x>0 and y>0), wherein the silicon oxynitride extends throughout the entire volume of the monolithic crucible body.
US08664132B2	High transmittance glass A high transmittance glass includes: SiO2 in the range of 65 to 75 weight percent; Na2O in the range of 10 to 20 weight percent; CaO in the range of 5 to 15 weight percent; MgO in the range of 0 to 5 weight percent; Al2O3 in the range of 0 to 5 weight percent; K2O in the range of 0 to 5 weight percent; MnO2 in the range of 0.035 to 0.6 weight percent; FeO in the range of 0.0010 to 0.0030 weight percent; and Fe2O3 (total iron) in the range of 0.001 to 0.03 weight percent. The glass has a redox ratio in the range of 0.1 to 0.4.
US08664130B2	White, opaque β-spodumene/rutile glass-ceramic articles and methods for making the same Crystallizable glasses, glass-ceramics, IXable glass-ceramics, and IX glass-ceramics are disclosed. The glass-ceramics exhibit β-spodumene ss as the predominant crystalline phase. These glasses and glass-ceramics, in mole %, include: 62-75 Si O2; 10.5-17 Al2O3; 5-13 Li2O; 0-4 ZnO; 0-8 MgO; 2-5 TiO2; 0-4 B2O3; 0-5 Na2O; 0-4 K2O; 0-2 ZrO2; 0-7 P2O5; 0-0.3 Fe2O3; 0-2 MnOx; and 0.05-0.2 SnO2. Additionally, these glasses and glass-ceramics exhibit the following criteria: a. a ratio: [ Li 2 ⁢ O + Na 2 ⁢ O + K 2 ⁢ O + MgO + ZnO ] [ Al 2 ⁢ O 3 + B 2 ⁢ O 3 ] between 0.7 to 1.5; b. a ratio: [ TiO 2 + SnO 2 ] [ SiO 2 + B 2 ⁢ O 3 ] greater than 0.04. Furthermore, the glass-ceramics exhibit an opacity ≧about 85% over the wavelength range of 400-700 nm for an about 0.8 mm thickness and colors an observer angle of 10° and a CIE illuminant F02 determined with specular reflectance included of a* between −3 and +3, b* between −6 and +6, and L* between 88 and 97.
US08664124B2	Method for etching organic hardmasks A method of etching or removing an organic hardmask overlying a low dielectric constant film in a lithographic process. The method includes providing a dielectric film having thereover an organic hardmask to be removed, the dielectric film having a dielectric constant no greater than about 4.0, introducing over the organic hardmask an ionizable gas comprising a mixture of hydrogen and an oxidizing gas, and applying energy to the mixture to create a plasma of the mixture. The method further includes contacting the organic hardmask with the plasma, with the organic hardmask being at a temperature in excess of 200° C., to remove the organic hardmask without substantially harming the underlying substrate.
US08664123B2	Method for manufacturing nitride semiconductor substrate There is provided a method for manufacturing a nitride semiconductor substrate, comprising: etching and flattening a surface of a nitride semiconductor substrate disposed facing a surface plate, by using the surface plate having a surface composed of any one of Ni, Ti, Cr, W, and Mo or nitride of any one of them, disposing the surface of the surface plate and a flattening surface of a nitride semiconductor substrate proximately so as to be faced each other, and supplying gas containing at least hydrogen and ammonia between the surface of the surface plate and the surface of the nitride semiconductor substrate, wherein the surface plate and the nitride semiconductor substrate facing each other are set in a high temperature state of 900° C. or more.
US08664119B2	Semiconductor device manufacturing method A semiconductor device manufacturing method, comprising: providing a semiconductor substrate, on which a gate conductor layer as well as a source region and a drain region positioned on both sides of the gate conductor layer are provided, forming an etch stop layer on the semiconductor substrate, forming an LTO layer on the etch stop layer, chemical mechanical polishing the LTO layer, forming an SOG layer on the polished LTO layer, the etch stop layer, LTO layer and SOG layer forming a front metal insulating layer, back etching the SOG layer and etch stop layer of the front metal insulating layer to expose the gate conductor layer, and removing the gate conductor layer.
US08664118B2	Semiconductor device and method for manufacturing the same An object is to provide a semiconductor device having excellent characteristics, in which a channel layer includes an oxide semiconductor with high crystallinity. In addition, a semiconductor device including a base film with improved planarity is provided. CMP treatment is performed on the base film of the transistor and plasma treatment is performed thereon after the CMP treatment, whereby the base film can have a center line average roughness Ra75 of less than 0.1 nm. The oxide semiconductor layer with high crystallinity is formed over the base film having planarity, which is obtained by the combination of the plasma treatment and the CMP treatment, thereby improving the characteristics of the semiconductor device.
US08664113B2	Multilayer interconnect structure and method for integrated circuits A multilayer interconnect structure is formed by, providing a substrate having thereon a first dielectric for supporting a multi-layer interconnection having lower conductor MN, upper conductor MN+1, dielectric interlayer (DIL) and interconnecting via conductor VN+1/N. The lower conductor MN has a first upper surface located in a recess below a second upper surface of the first dielectric. The DIL is formed above the first and second surfaces. A cavity is etched through the DIL from a desired location of the upper conductor MN+1, exposing the first surface. The cavity is filled with a further electrical conductor to form the upper conductor MN+1 and the connecting via conductor VN+1/N making electrical contact with the first upper surface. A critical dimension between others of lower conductors MN and the via conductor VN+1/N is lengthened. Leakage current and electro-migration there-between are reduced.
US08664112B2	Methods for forming interconnect structures for integration of multi-layered integrated circuit devices Semiconductor devices comprise at least one integrated circuit layer, at least one conductive trace and an insulative material adjacent at least a portion of the at least one conductive trace. At least one interconnect structure extends through a portion of the at least one conductive trace and a portion of the insulative material, the at least one interconnect structure comprising a transverse cross-sectional dimension through the at least one conductive trace which differs from a transverse cross-sectional dimension through the insulative material. Methods of forming semiconductor devices comprising at least one interconnect structure are also disclosed.
US08664107B2	Method for applying liquid material, application device and program Disclosed are an application method, device and program which enable the constant retention of a fillet shape, without altering the shape due to the speed differences associated with changes in the direction of the nozzle or differences in the degree of penetration when bumps are arranged non-uniformly. In a liquid material application method a desired application pattern is created, liquid material is discharged from a nozzle whilst the nozzle and a workpiece are moved relative to one another, and the gap between a substrate and the workpiece, the workpiece being placed above the substrate by means of at least three bumps, is filled up with liquid material by capillary action. If bumps are arranged non-uniformly, the supply quantity per unit area of the application pattern is set so that a greater quantity is supplied to application areas next to areas where the integration density of bumps is high, than is supplied to application areas next to areas where the integration density of bumps is low.
US08664104B2	Method of producing a device with transistors strained by means of an external layer A method of producing a microelectronic device with transistors wherein a strain layer is formed on a series of transistors and the strain exerted on at least one given transistor of said series is released by removing a sacrificial layer situated between said given transistor and said strain layer.
US08664102B2	Dual sidewall spacer for seam protection of a patterned structure A semiconducting device with a dual sidewall spacer and method of forming are provided. The method includes: depositing a first spacer layer over a patterned structure, the first spacer layer having a seam propagating through a thickness of the first spacer layer near an interface region of a surface of the substrate and a sidewall of the patterned structure, etching the first spacer layer to form a residual spacer at the interface region, where the residual spacer coats less than the entirety of the sidewall of the patterned structure, depositing a second spacer layer on the residual spacer and on the sidewall of the patterned structure not coated by the residual spacer, the second spacer layer being seam-free on the seam of the residual spacer, and etching the second spacer layer to form a second spacer coating the residual spacer and coating the sidewall of the patterned structure not coated by the residual spacer.
US08664098B2	Plasma processing apparatus A plasma processing apparatus includes a process chamber, a platen for supporting a workpiece, a source configured to generate a plasma in the process chamber, and an insulating modifier. The insulating modifier has a gap, and a gap plane, where the gap plane is defined by portions of the insulating modifier closest to the sheath and proximate the gap. A gap angle is defined as the angle between the gap plane and a plane defined by the front surface of the workpiece. Additionally, a method of having ions strike a workpiece is disclosed, where the range of incident angles of the ions striking the workpiece includes a center angle and an angular distribution, and where the use of the insulating modifier creates a center angle that is not perpendicular to the workpiece.
US08664094B2	Method of producing nitride nanowires with different core and shell V/III flow ratios The present invention relates to the growing of nitride semiconductors, applicable for a multitude of semiconductor devices such as diodes, LEDs and transistors. According to the method of the invention nitride semiconductor nanowires are grown utilizing a CVD based selective area growth technique. A nitrogen source and a metal-organic source are present during the nanowire growth step and at least the nitrogen source flow rate is continuous during the nanowire growth step. The V/III-ratio utilized in the inventive method is significantly lower than the V/III-ratios commonly associated with the growth of nitride based semiconductor.
US08664091B2	Method for removing metallic nanotube A method for removing a metallic nanotube, which is formed on a substrate in a first direction, includes forming a plurality of conductors in a second direction crossing the first direction, electrically contacting the plurality of conductors with metallic nanotube, respectively, forming at least two voltage-applying electrodes on the conductors, each of which electrically contacting at least one of the conductors, and applying voltages to at least some of the conductors through the voltage-applying electrodes, respectively. Among the conductors to which the voltages are respectively applied, every two adjacent conductors have an electrical potential difference created therebetween, so as to burn out the metallic nanotube.
US08664089B1	Semiconductor die singulation method In one embodiment, semiconductor die are singulated from a semiconductor wafer having a backmetal layer by placing the semiconductor wafer onto a carrier tape with the backmetal layer adjacent the carrier tape, forming singulation lines through the semiconductor wafer to expose the backmetal layer within the singulation lines, and fluid machining the semiconductor wafer to remove the backmetal layer from the singulation lines.
US08664085B2	Method of manufacturing composite substrate A composite-substrate manufacturing method is provided with: a step of carrying out implantation of ions through a surface of a bulk substrate composed of the nitride compound semiconductor; a step of setting said surface of the bulk substrate against the second substrate, and bonding the bulk substrate and the second substrate together to obtain a bonded substrate; a step of elevating the temperature of the bonded substrate to a first temperature; a step of sustaining the first temperature for a fixed time; and a step of producing a composite substrate by severing the remaining portion of the bulk substrate from the bonded substrate; characterized in that a predetermined formula as for the first temperature, the thermal expansion coefficient of the first substrate, and the thermal expansion coefficient of the second substrate is satisfied.
US08664083B2	Vertical outgassing channels InP epitaxial material is directly bonded onto a Silicon-On-Insulator (SOI) wafer having Vertical Outgassing Channels (VOCs) between the bonding surface and the insulator (buried oxide, or BOX) layer. H2O and other molecules near the bonding surface migrate to the closest VOC and are quenched in the buried oxide (BOX) layer quickly by combining with bridging oxygen ions and forming pairs of stable nonbridging hydroxyl groups (Si—OH). Various sizes and spacings of channels are envisioned for various devices.
US08664081B2	Method for fabricating 3D integrated circuit device using interface wafer as permanent carrier A computer readable medium is provided that is encoded with a program comprising instructions for performing a method for fabricating a 3D integrated circuit structure. Provided are an interface wafer including a first wiring layer and through-silicon vias, and a first active circuitry layer wafer including active circuitry. The first active circuitry layer wafer is bonded to the interface wafer. Then, a first portion of the first active circuitry layer wafer is removed such that a second portion remains attached to the interface wafer. A stack structure including the interface wafer and the second portion of the first active circuitry layer wafer is bonded to a base wafer. Next, the interface wafer is thinned so as to form an interface layer, and metallizations coupled through the through-silicon vias in the interface layer to the first wiring layer are formed on the interface layer.
US08664079B2	Method of fabricating semiconductor device by thinning hardmask layers on frontside and backside of substrate The disclosure relates to integrated circuit fabrication, and more particularly to a method for fabricating a semiconductor device. An exemplary method for fabricating the semiconductor device comprises providing a substrate; forming pad oxide layers over a frontside and a backside of the substrate; forming hardmask layers over the pad oxide layers on the frontside and the backside of the substrate; and thinning the hardmask layer over the pad oxide layer on the frontside of the substrate.
US08664075B2	High capacitance trench capacitor A dual node dielectric trench capacitor includes a stack of layers formed in a trench. The stack of layers include, from bottom to top, a first conductive layer, a first node dielectric layer, a second conductive layer, a second node dielectric layer, and a third conductive layer. The dual node dielectric trench capacitor includes two back-to-back capacitors, which include a first capacitor and a second capacitor. The first capacitor includes the first conductive layer, the first node dielectric layer, the second conductive layer, and the second capacitor includes the second conductive layer, the second node dielectric layer, and the third conductive layer. The dual node dielectric trench capacitor can provide about twice the capacitance of a trench capacitor employing a single node dielectric layer having a comparable composition and thickness as the first and second node dielectric layers.
US08664073B2	Method for fabricating field-effect transistor A method for fabricating complimentary metal-oxide-semiconductor field-effect transistor is disclosed. The method includes the steps of: (A) forming a first gate structure and a second gate structure on a substrate; (B) performing a first co-implantation process to define a first type source/drain extension region depth profile in the substrate adjacent to two sides of the first gate structure; (C) forming a first source/drain extension region in the substrate adjacent to the first gate structure; (D) performing a second co-implantation process to define a first pocket region depth profile in the substrate adjacent to two sides of the second gate structure; (E) performing a first pocket implantation process to form a first pocket region adjacent to two sides of the second gate structure.
US08664070B2	High temperature gate replacement process A method for fabricating an integrated circuit device is disclosed. An exemplary method comprises performing a gate replacement process to form a gate structure, wherein the gate replacement process includes an annealing process; after the annealing process, removing portions of a dielectric material layer to form a contact opening, wherein a portion of the substrate is exposed; forming a silicide feature on the exposed portion of the substrate through the contact opening; and filling the contact opening to form a contact to the exposed portion of the substrate.
US08664064B2	Fin field effect transistor and method for forming the same Example embodiments are directed to a method of forming a field effect transistor (FET) and a field effect transistor (FET) including a source/drain pair that is elevated with respect to the corresponding gate structure.
US08664060B2	Semiconductor structure and method of fabricating the same A semiconductor structure and a method of fabricating the same comprising the steps of providing a substrate, forming at least one fin structure on said substrate, forming a gate covering said fin structure, forming a plurality of epitaxial structures covering said fin structures, performing a gate pullback process to reduce the critical dimension (CD) of said gate and separate said gate and said epitaxial structures, forming lightly doped drains (LDD) in said fin structures, and forming a spacer on said gate and said fin structures.
US08664057B2	High-K metal gate electrode structures formed by early cap layer adaptation When forming high-k metal gate electrode structures in transistors of different conductivity type while also incorporating an embedded strain-inducing semiconductor alloy selectively in one type of transistor, superior process uniformity may be accomplished by selectively reducing the thickness of a dielectric cap material of a gate layer stack above the active region of transistors which do not receive the strain-inducing semiconductor alloy. In this case, superior confinement and thus integrity of sensitive gate materials may be accomplished in process strategies in which the sophisticated high-k metal gate electrode structures are formed in an early manufacturing stage, while, in a replacement gate approach, superior process uniformity is achieved upon exposing the surface of a placeholder electrode material.
US08664055B2	Fin field-effect transistor structure and manufacturing process thereof A fin field-effect transistor structure includes a substrate, a fin channel and a high-k metal gate. The high-k metal gate is formed on the substrate and the fin channel. A process of manufacturing the fin field-effect transistor structure includes the following steps. Firstly, a polysilicon pseudo gate structure is formed on the substrate and a surface of the fin channel. By using the polysilicon pseudo gate structure as a mask, a source/drain region is formed in the fin channel. After the polysilicon pseudo gate structure is removed, a high-k dielectric layer and a metal gate layer are successively formed. Afterwards, a planarization process is performed on the substrate having the metal gate layer until the first dielectric layer is exposed, so that a high-k metal gate is produced.
US08664054B2	Method for forming semiconductor structure The invention relates to a method for forming a semiconductor structure, comprising: providing a semiconductor substrate which comprises a dummy gate formed thereon, a spacer surrounding the dummy gate, source and drain regions formed on two sides of the dummy gate, respectively, and a channel region formed in the semiconductor substrate and below the dummy gate; removing the dummy gate to form a gate opening; forming a stressed material layer in the gate opening; performing an annealing to the semiconductor substrate, the stressed material layer having tensile stress characteristics during the annealing; removing the stressed material layer in the gate opening; and forming a gate in the gate opening. By the above steps, the stress memorization technique can be applied to the pMOSFET.
US08664053B2	Semiconductor device with isolation structures and gate insulating film that contain an element for threshold reduction and method of manufacturing the same A device isolation region is made of a silicon oxide film embedded in a trench, an upper portion thereof is protruded from a semiconductor substrate, and a sidewall insulating film made of silicon nitride or silicon oxynitride is formed on a sidewall of a portion of the device isolation region which is protruded from the semiconductor substrate. A gate insulating film of a MISFET is made of an Hf-containing insulating film containing hafnium, oxygen and an element for threshold reduction as main components, and a gate electrode that is a metal gate electrode extends on an active region, the sidewall insulating film and the device isolation region. The element for threshold reduction is a rare earth or Mg when the MISFET is an n-channel MISFET, and the element for threshold reduction is Al, Ti or Ta when the MISFET is a p-channel MISFET.
US08664044B2	Method of fabricating land grid array semiconductor package A fan-out wafer level package is provided with a semiconductor die embedded in a reconstituted wafer. A redistribution layer is positioned over the semiconductor die, and includes a land grid array on a face of the package. A copper heat spreader is formed in the redistribution layer over the die in a same layer as a plurality of electrical traces configured to couple circuit pads of the semiconductor die to respective contact lands of the land grid array. In operation, the heat spreader improves efficiency of heat transfer from the die to the circuit board.
US08664042B2	Method for fabrication of configurable systems A method to construct configurable systems, the method including: providing a first configurable system including a first die and a second die, where the connections between the first die and the second die include through-silicon-via (“TSV”), where the first die is diced from a first wafer using first dice lines; providing a second configurable system including a third die and a fourth die, where the connections between the third die and the fourth die include through-silicon-via (“TSV”), where the third die is diced from a third wafer using third dice lines; and processing the first wafer and the third wafer utilizing at least 20 masks that are the same; where the first dice lines are substantially different than the third dice lines, and where the second die includes a configurable I/O to connect the first configurable system to external devices.
US08664036B2	Semiconductor device and manufacturing method thereof An oxide semiconductor layer with excellent crystallinity is formed to enable manufacture of transistors with excellent electrical characteristics for practical application of a large display device, a high-performance semiconductor device, etc. By first heat treatment, a first oxide semiconductor layer is crystallized. A second oxide semiconductor layer is formed over the first oxide semiconductor layer. By second heat treatment, an oxide semiconductor layer including a crystal region having the c-axis oriented substantially perpendicular to a surface is efficiently formed and oxygen vacancies are efficiently filled. An oxide insulating layer is formed over and in contact with the oxide semiconductor layer. By third heat treatment, oxygen is supplied again to the oxide semiconductor layer. A nitride insulating layer containing hydrogen is formed over the oxide insulating layer. By fourth heat treatment, hydrogen is supplied at least to an interface between the second oxide semiconductor layer and the oxide insulating layer.
US08664031B2	Method of manufacturing photodiode intergrated chip A semiconductor device manufacturing method including a process of forming a silicon oxide film by thermally oxidizing silicon in the atmosphere of oxygen gas or in the atmosphere of mixed gas of oxygen and hydrogen at a temperature of 800° C. or more in the state in which at least the silicon surface serving as a light-receiving portion of a photodiode is exposed, and a process of depositing a silicon nitride film on the silicon oxide film. At least the silicon oxide film and the silicon nitride film are finally left on the surface of the photodiode as an antireflection film.
US08664030B2	Collector grid and interconnect structures for photovoltaic arrays and modules An interconnected arrangement of photovoltaic cells is achieved using laminating current collector electrodes. The electrodes comprise a pattern of conductive material extending over a first surface of sheetlike substrate material. The first surface comprises material having adhesive affinity for a selected conductive surface. Application of the electrode to the selected conductive surface brings the first surface of the sheetlike substrate into adhesive contact with the conductive surface and simultaneously brings the conductive surface into firm contact with the conductive material extending over first surface of the sheetlike substrate. Use of the laminating current collector electrodes allows facile and continuous production of expansive area interconnected photovoltaic arrays.
US08664026B2	Method for fabricating semiconductor lighting chip A method for fabricating a semiconductor lighting chip includes steps of providing a substrate with an epitaxial layer thereon. The epitaxial layer comprises a first semiconductor layer, an active layer and a second semiconductor layer successively grown on the substrate. The epitaxial layer has dislocation defects traversing the first semiconductor layer, the active layer and the second semiconductor layer. The epitaxial layer is then subjected to an etching process which remove parts of the second semiconductor layer and the active layer along the dislocation defects to form recesses recessing from the second semiconductor layer to the active layer. Thereafter a first electrode and a second electrode are formed on the first semiconductor layer and the second semiconductor layer, respectively.
US08664025B2	Substrate dicing technique for separating semiconductor dies with reduced area consumption The width of scribe lines may be reduced in semiconductor devices by applying a process technique in which trenches may be formed first from the rear side on the basis of a required width of the corresponding trenches, while subsequently it may be cut into the substrate from the front side on the basis of a reduced thickness of the corresponding saw blades, thereby also enabling a reduction of the scribe line width. Furthermore, contamination of the front side, i.e., of the metallization system, may be reduced, for instance, by performing an optional intermediate cleaning process.
US08664019B2	Vertical group III-nitride light emitting device and method for manufacturing the same A vertical group III-nitride light emitting device and a manufacturing method thereof are provided. The light emitting device comprises: a conductive substrate; a p-type clad layer stacked on the conductive substrate; an active layer stacked on the p-type clad layer; an n-doped AlxGayIn1-x-yN layer stacked on the active layer; an undoped GaN layer stacked on the n-doped layer; and an n-electrode formed on the undoped GaN layer. The undoped GaN layer has a rough pattern formed on a top surface thereof.
US08664018B2	Manufacturing method for LED package The disclosure provides a manufacturing method for an LED package. A first luminescent conversion layer comprising one first luminescent conversion element is located on an LED chip, wherein the first luminescent conversion element is precipitated via centrifugation around the LED chip without sheltering the LED chip. Thereafter, a second luminescent conversion layer is located on the first luminescent conversion layer. The second luminescent layer has a second luminescent conversion element which has an excited efficiency lower that that of the first luminescent conversion element.
US08664017B2	Method of manufacturing organic light emitting device Provided is a method of manufacturing an organic light emitting device capable of suppressing a patterning defect caused by a residue of a release layer, the method including: a first organic compound layer formation step; a first protective layer formation step; a second protective layer formation step; a second protective layer processing step; a first protective layer processing step; a first organic compound layer processing step; a second organic compound layer formation step; and a lift-off step in which the pattern of the second protective layer obtained in the second protective layer processing step is formed also in a second region.
US08664014B2	High productivity combinatorial workflow for photoresist strip applications Electrical testing of metal oxide semiconductor (MOS) high-k capacitor structures is used to evaluate photoresist strip or cleaning chemicals using a combinatorial workflow. The electrical testing can be able to identify the damages on the high-k dielectrics, permitting a selection of photoresist strip chemicals to optimize the process conditions in the fabrication of semiconductor devices. The high productivity combinatorial technique can provide a compatibility evaluation of photoresist strip chemicals with high-k devices.
US08664013B2	Continuous processing system, continuous processing method, and program In a continuous processing system, a controller of a heat treatment apparatus calculates a weight of each layer from input target film thicknesses of a phosphorous-doped polysilicon film (D-poly film) and an amorphous silicon film (a-Si film), and calculates activation energy of stacked films based on the calculated weight and activation energy. The controller prepares a stacked film model based on the calculated activation energy and a relationship of a temperature of each zone and film thicknesses of the D-poly film and the a-Si film, and calculates an optimum temperature of each zone by using the prepared stacked film model. The controller controls power controllers of heaters to set a temperature in a reaction tube to be the calculated temperature of each zone and forms stacked films on a semiconductor wafer by controlling a pressure adjusting unit, flow rate adjusting units, etc.
US08664012B2	Combined silicon oxide etch and contamination removal process A method of forming a semiconductor device. A substrate having first and second materials is provided, wherein the second material is occluded by the first material. The substrate is etched using a first non-plasma etch process that etches the first material at a higher rate relative to a rate of etching the second material. The first non-plasma etch process exposes the second material that is overlying at least a portion of the first material. The second material is then etched using a plasma containing a reactive gas, which exposes the at least a portion of the first material. The first material including the at least a portion of the first material that was exposed by etching the second material are etched using a second non-plasma etch process.
US08664009B2	Arsenical fluorescent agents and assays The invention provides methods and compositions for labeling dithiol-containing analytes.
US08664008B2	Enzymatic signal generation and detection of binding complexes in stationary fluidic chip An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.
US08664000B2	Analyte ionization by charge exchange for sample analysis under ambient conditions Electrospray ionization techniques are used to generate reagents that ionize analytes for mass spectrometric analysis by charge transfer. Such techniques may be performed under ambient conditions. Suitable precursors for such reagents include ionizable nonpolar solvents, such as toluene or xylenes, polar solvents, such as water or alchohols, inert gases, such as helium or nitrogen, or combinations thereof. Environmental conditions in the ionization chamber of the mass spectrograph can be manipulated to generate a selected ion of an analyte in preference to other ions.
US08663999B2	Characterization of N-glycan mixtures by nuclear magnetic resonance The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in characterizing monosaccharide composition, branching, fucosylation, sulfation, phosphorylation, sialylation linkages, presence of impurities and/or efficiency of a labeling procedure (e.g., labeling with a fluorophore such as 2-AB). In certain embodiments, the methods can be used quantitatively. In certain embodiments, the methods can be combined with enzymatic digestion to further characterize glycan mixtures.
US08663998B2	Color changeable dyes for indicating exposure, methods of making and using such dyes, and apparatuses incorporating such dyes According to embodiments of the present application, a color changeable dye can comprise a redox indicator, a reduction reaction initiator, an electron donor, an oxygen scavenger, an indicator barrier agent, a thickening agent and an agent to facilitate mixing. The color changeable dye is a first color in the presence of oxygen, capable of changing to a second color upon reduction in a substantially oxygen free environment, and capable of changing back to the first color after exposure to oxygen for a period of time corresponding to the intended use time of a disposable or limited use product. Methods of making and using the color changeable dye and apparatuses incorporating such dye are also disclosed.
US08663996B2	Determining oxygen concentration in ullage using catalytic oxidation A system for measuring the oxygen concentration of a gas includes a catalytic reactor, first and second temperature sensors and a control unit. The catalytic reactor includes a combustion catalyst that supports the catalytic combustion of hydrocarbon fuel vapor in a gas stream. The first temperature sensor is located upstream of the catalytic reactor for sensing an upstream temperature of the gas stream, and the second temperature sensor is located downstream of the catalytic reactor for sensing a downstream temperature of the gas stream. The control unit compares the upstream temperature and the downstream temperature to determine the oxygen concentration of the gas stream.
US08663994B2	Analysis of mannosamine-containing capsular saccharides Analysis of compositions that include saccharides having mannosamine residues, such as the capsular saccharide of N. meningitidis serogroup A, is facilitated by a method comprising the steps of: (i) hydrolysing polysaccharide in the sample, to give a hydrolysate; (ii) subjecting the hydrolysate to liquid chromatography; and (iii) detecting any mannosamine-6-phosphate separated in step (ii).
US08663993B2	Automated protein analyzer A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances. An electronic signal is created based upon the absorbance of a successive dye filtrate solution prepared from the reference dye solution and a successive protein sample, and the absorbance signal from the successive sample dye filtrate solution is sent to the processor to calculate the protein content of the successive sample based upon the difference between the absorbance of the initial reference dye solution and the absorbance of the successive dye filtrate solution.
US08663990B2	Measurement method utilizing internal standard substance A subject of the present invention is to provide a measurement method using an internal standard substance in an electrophoresis where an analyte is a protein or a compound. The present invention relates to a measurement method for an analyte by an electrophoresis, characterized in that a peak of the analyte is identified by using as an internal standard substance (1) a combination of a compound I having 3 or more anion groups in a molecule and a compound II where 1 to 3 groups of the anion groups of said compound I have been substituted by cation groups, or (2) a combination of a compound III having 3 or more cation groups in a molecule and a compound IV where 1 to 3 groups of the cation groups of said compound III have been substituted by cation groups.
US08663989B2	Retroviral vector particles and methods for their generation and use The present invention relates to methods of host cell transduction utilizing ecotropic retroviral vector particles. The retroviral vector particle may comprise an envelope of Friend murine leukaemia virus, in particular the envelope encoded by molecular clone PVC-211 and the host cell may be engineered to recombinantly express the Reel receptor. The retroviral vector particles and methods of the invention can be used to introduce expressible polynucleotide sequences of interest into host cells with high efficiency. This results in protein production methods with higher yield (mg/L) and a reduction in manufacturing costs that could be used in a range of applications including for example, the production of therapeutic proteins, vaccines and antibodies.
US08663983B2	Cells useful for immuno-based botulinum toxin serotype A activity assays The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
US08663981B2	Optimized promoter sequence A modified CAG promoter which is capable of driving high levels of expression of sequences of interest inserted downstream therefrom is herein described.
US08663974B2	Compositions and methods for capture and elution of biological materials via particulates Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. Binding of biological materials to solid surfaces may be induced by particular media. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Lysing materials may include particles of different sizes. Heating may be used. Lysing may be performed in a flow through apparatus. Surfaces of solid materials may be modified to capture bacteria with high cell wall lipid content.
US08663969B2	Hybrid mushroom strain J9277, its descendants, and related methods A mushroom culture of Agaricus bisporus produced by hybridization of a first strain and a second strain of Agaricus bisporus, wherein at least one of said first and second strains of Agaricus is a hybrid mushroom culture of Agaricus bisporus designated strain J9277. Diverse additional strains can be developed from J9277 by various means including somatic and tissue culture selection, basidiospore selection, and hybridization to other strains of Agaricus bisporus, and the resulting derivative strains can be screened for desirable commercial characteristics. One resultant class of the mushroom Agaricus bisporus (J. Lange) Imbach is the hybrid strain J10165. It exhibits an attractive appearance that includes a smooth, bright white cap, and is biologically incompatible with strains of the ‘U1’ lineage group. A method for improving facility hygiene and reducing disease incidence at any commercial Agaricus bisporus mushroom production facility is also provided.
US08663967B2	Arginine deiminase mutant and preparation and application thereof The present invention relates to an arginine deiminase mutant with partial lysine-deficient and preparation and application thereof. The arginine deiminase mutant of the present invention has enzymatic activity of degrading arginine into citruline; compared with the arginine deiminase with the amino acid sequence of SEQ ID NO: 1, the amino acid sequence comprises one or more of K9N, T, K59Q, K66R, A, K93E, A, Q, K111R, A, K119Q, L, M, K121Q, I, K122E, L, K126E, S, R, K178I, E, D, K196I, R, K209G, T, D, K243E, V, R, K249D, Q, K263N, Q, K279Y, T, K293R, H, E, K325V, I, K380T, R, E, and K406E, D, S substitutions. Compared with PEG modified natural derived arginine deiminase, the PEG modified arginine deiminase mutant of the present invention retain better bioactivity; and because the quantity of lysine in arginine deiminase is reduced, the PEG modified products are more uniform and can be applied to clinical treatment of hepatoma, melanoma and the like.
US08663959B2	Preparing biological samples for analysis Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
US08663958B2	Oxygen-resistant hydrogenases and methods for designing and making same The invention provides oxygen-resistant iron-hydrogenases ([Fe]-hydrogenases) for use in the production of H2. Methods used in the design and engineering of the oxygen-resistant [Fe]-hydrogenases are disclosed, as are the methods of transforming and culturing appropriate host cells with the oxygen-resistant [Fe]-hydrogenases. Finally, the invention provides methods for utilizing the transformed, oxygen insensitive, host cells in the bulk production of H2 in a light catalyzed reaction having water as the reactant.
US08663955B2	Method for producing carboxylic acids having 1-3 carbon atoms from renewable resources The invention relates to a method for producing carboxylic acids having 1-3 carbon atoms, characterized in that 2,3-butanediol and/or acetoin are reacted to form carboxylic acids having 1-3 carbon atoms.
US08663954B2	Fermentation of moderately thermophilic bacilli on sucrose A method for the construction of a moderately thermophilic Bacillus strain capable of utilizing sucrose as a carbon source includes the transformation of a parent moderately thermophilic Bacillus strain not capable of utilizing sucrose as a carbon source with a polynucleotide comprising a DNA sequence that encodes a polypeptide having sucrose-specific phosphotransferase activity and having i) an amino acid sequence of SEQ ID NO:1 or ii) an amino acid sequence with an identity of at least 70% to the sequence of SEQ ID NO:1 and/or comprising a DNA sequence that encodes a polypeptide having sucrose-6-phosphate hydrolase activity and having iii) an amino acid sequence of SEQ ID NO:2 or iv) an amino acid sequence with an identity of at least 70% to the sequence of SEQ ID NO:2.
US08663952B2	Method of producing corn starch by enzymatic process A method of producing corn starch by enzymatic process involving: soaking the corn; crushing the corn, separating and washing embryo; fine grinding; washing and drying fiber; separating and drying protein; washing, dewatering and drying the starch. An enzyme preparation is added before the step of washing, dewatering and drying the starch; the enzyme preparation is cellulose, or xylanase, or combination of the cellulose and the xylanase; and addition of the enzyme preparation is from 0.001% to 0.08% by weight of the corn. Based on the technology of traditional wet process, the method of the present invention comprises a step of adding enzyme preparation in the process of separating the corn, which improves the effect and the efficiency of mechanical separation, and further improves the purity and yield of the substance separated while also reducing the energy consumption.
US08663950B2	Production of a monoclonal antibody therapeutic against west nile virus in plants The present invention describes the plant-based production of a therapeutic antibody against West Nile Virus.
US08663948B2	Host, transformant and method for producing the transformant and method for producing O-glycosylated heterologous protein The object is to provide a transformant which can produce a heterologous protein having a structurally controlled O-linked sugar chain having an O-Man-Gal disaccharide structure, a method for producing the transformant by using Schizosaccharomyces pombe as the host, and provide a host for producing the transformant and a method for producing an O-glycosylated heterologous protein.An Schizosaccharomyces pombe host having no omh1 gene or an inactivated omh1 gene in its chromosomes for producing an O-glycosylated heterologous protein having an O-linked sugar chain having an O-Man-Gal disaccharide structure by expression of the heterologous protein by a genetic engineering technique and subsequent glycosylation of the expressed heterologous protein. A transformant from the host, a method for producing the transformant and a method for producing an O-glycosylated heterologous protein by using the transformant.
US08663947B2	Nuclear localization of Src-family tyrosine kinases is required for growth factor-induced euchromatinization A method for quantitatively evaluating chromatin structural changes using pixel imaging of the nucleus is provided. Pixel imaging of the nucleus can include capturing one or more images of a nucleus of one or more nucleic acid stain treated cells. The stain intensity can be measured by quantitating the intensity. The mean and/or standard deviation of stain intensity per pixel can be used to determine chromatin condensation levels or chromatin structural change.
US08663943B2	Antibodies for discrimination of prions In the present invention, we described the use of anti-DNA antibody for the detection of prions and diagnosis of Transmissible Spongiform Encephalopathies (TSE) diseases in animals and humans.
US08663940B2	Ex-vivo passive protection bacteremia assay The present disclosure provides methods for assessing bactericidal antibodies in a biological sample by use of human fresh whole blood from a non-immune human as a reaction medium for the assay.
US08663934B2	Cloned transmembrane receptor for 24-hydroxylated vitamin D compounds and uses thereof The instant invention relates to the use of 24-hydroxylated vitamin D compounds as therapeutics in mammalian bone fracture repair. In addition, the instant invention relates to novel 24-hydroxylated vitamin D compound receptors which can be employed in the development of compounds capable of facilitating fracture repair in animals. The instant invention also relates to nucleic acids encoding such receptors as well as vectors, host cells, transgenic animals comprising such nucleic acids and screening assays employing such receptors.
US08663931B2	Method for detecting renal disease comprising measuring human megalin in urine This invention provides a diagnostic kit and a diagnostic marker used for diagnosing a renal disease. This invention also provides a method for detecting a renal disease comprising measuring at least one type of human megalin existing in urine selected from among full-length human megalin and human megalin fragments of (i) to (iii): (i) full-length human megalin; (ii) a human megalin endodomain fragment lacking a human megalin ectodomain; and (iii) a human megalin ectodomain fragment lacking a human megalin endodomain.
US08663930B2	Methods and means for treatment of osteoarthritis The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
US08663928B2	Method for the detection of post-translational modifications Method for the detection in homogeneous medium of a post-translational modification of a proteinaceous substrate catalyzed by a cell enzyme, characterized in that the post-translational modification reaction takes place in intact living cells, in that these cells comprise a heterologous expression vector coding for a fusion protein comprising the proteinaceous substrate and a first coupling domain and in that it comprises the following stages: (i) Incubation of the cells in the presence or in the absence of a compound to be tested capable of modulating the activity of said enzyme, (ii) Addition to the reaction medium of a first fluorescent compound member of a first pair of FRET partners covalently bonded to a coupling agent capable of binding specifically to the first coupling domain present on the proteinaceous substrate, (iii) Addition to the reaction medium of a second fluorescent compound member of this first pair of FRET partners, and covalently bonded to a binding domain specific to the site of the proteinaceous substrate having undergone the post-translational modification and not binding to the non-modified proteinaceous substrate, (i) Measurement of the FRET signal emitted by the sample, this signal being representative of the quantity of proteinaceous substrate having undergone said post-translational modification; and cells for the implementation of said method.
US08663916B2	Methods for producing antifungal bifunctional molecules for treating fungal infection The present invention is directed to methods of using nucleic acid molecules encoding for fusion peptides to produce the fusion peptides. The methods can include preparing or providing the nucleic acid molecules that having a fungal targeting agent (e.g., a fungal pheromone, such as alpha-mating pheromone) and a channel-forming domain consisting essentially of amino acids 451-626 of colicin Ia. The nucleic acid molecules can be transfected into host cells to produce the fusion peptide. The fusion peptides of the peptides of the present invention are particularly useful for the treatment of fungal infections in a wide variety of organisms.
US08663911B2	Method for detection of intestinal, and blood-brain barrier permeability and testing materials thereto Methods, assays, and apparatus are disclosed for testing of antigens associated with intestinal and/or blood-brain barrier permeability. For example, blood, saliva or other bodily fluid can be tested for binding (1) to a bacterial toxin (preferably a lipopolysaccharide), and (2) binding to tissue antigens selected from at least one of (a) a gut-related antigen and (b) a blood brain barrier-related antigen. Analysis of test results can be used to assist in detecting and diagnosing diseases associated with leaky gut syndrome (whether due to paracellular or transcellular pathways, and whether due to bacterial toxins or some other cause) and/or to diseases associated with excessive blood brain barrier permeability, which are contemplated herein to include both neuroinflammation and/or neuroautoimmunity conditions, and especially amyotrophic lateral sclerosis, Parkinsons disease, multiple sclerosis, Alzheimer's, or peripheral neuropathy, and major depression.
US08663909B2	Device for rapid detection and identification of single microorganisms without preliminary growth This invention describes a device consisting of a micro channel plate, filter, and porous holder for filter, which is substituted by a pure agar block during method performance, and supportive structural elements. The device is intended for rapid detection and/or identification of microorganisms. Microorganisms are trapped by filtration in long (diameter/length=1/10-1/100), cylindrical, parallel, micro-channels that are open from both sides and attached to a filter from one side. A micro channel plate houses a multiplicity of micro channels (possible diameter of each channel=1-30 μm, length 100-1000 μm, and number on centimeter2=100,000-1,000,000). The micro channel plate with cells trapped on the surface of the filter is attached to an agar block impregnated by artificial substrate(s) so that the molecules of the artificial substrates will fill all micro channels. Trapped cells produce colored or fluorescent molecules from artificial substrates. These molecules are collected in the very small volume of a micro channel. The extremely small volume of a micro channel (1/25 million part of milliliter) allows it to collect a detectable concentration of color or fluorescent substances in a very short time (several minutes). Even one cell from a filtrated sample can be detected by the enzyme—artificial substrate method and/or identified by enzyme immunoassay.
US08663907B2	Method of forming pattern Provided is a method of forming pattern including (a) forming a chemically amplified resist composition into a film, (b) exposing the film to light, and (c) developing the exposed film with a developer containing a first organic solvent, wherein in the developer, particles each having a diameter of 0.3 μm or greater amount to a density of 30 particles/ml or less.
US08663904B2	Norbornene-type polymers, compositions thereof and lithographic process using such compositions Embodiments in accordance with the present invention provide for non-self imageable norbornene-type polymers useful for immersion lithographic processes, methods of making such polymers, compositions employing such polymers and immersion lithographic processes that make use of such compositions. More specifically the embodiments of the present invention are related to norbornene-type polymers useful for forming top-coat layers for overlying photoresist layers in immersion lithographic process and the process thereof.
US08663901B2	Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same The present invention relates to a fluorine-free photoacid generator (PAG) and a photoresist composition containing the same. The PAG is characterized by the presence of an onium cationic component and a fluorine-free fused ring heteroaromatic sulfonate anionic component containing one or more electron withdrawing substituents. The onium cationic component of the PAG is preferably a sulfonium or an iodonium cation. The photoresist composition further contains an acid sensitive imaging polymer. The photoresist composition is especially useful for forming material patterns on a semiconductor substrate using 193 nm (ArF) lithography.
US08663900B2	Resist composition and method for producing resist pattern A resist composition having a resin having a structural unit represented by the formula (I), a resin being insoluble or poorly soluble in alkali aqueous solution, but becoming soluble in an alkali aqueous solution by the action of an acid and not including the structural unit represented by the formula (I), and an acid generator represented by the formula (II), wherein R1, A1, A13, A14, X12, RII1, RII2, LII1, YII1, RII3, RII4, RII5, RII6, RII7, n, s and RII8 are defined in the specification.
US08663898B2	Resist underlayer film composition and patterning process using the same There is disclosed A resist underlayer film composition, wherein the composition contains a polymer obtained by condensation of, at least, one or more compounds represented by the following general formulae (1-1) and/or (1-2), one or more kinds of a compound represented by the following general formula (2), and one or more kinds of a compound, represented by the following general formula (3), and/or an equivalent body thereof. There can be provided an underlayer film composition, especially for a trilayer resist process, that can form an underlayer film having reduced reflectance, (namely, an underlayer film having optimum n-value and k-value as an antireflective film), excellent filling-up properties, high pattern-antibending properties, and not causing line fall or wiggling after etching especially in a high aspect line that is thinner than 60 nm, and a patterning process using the same.
US08663897B2	Fluorine-containing sulfonates having polymerizable anions and manufacturing method therefor, fluorine-containing resins, resist compositions, and pattern-forming method using same According to the present invention, there is provided a polymerizable fluorine-containing sulfonic acid onium salt of the following general formula (2) and a resin obtained by polymerization thereof. It is possible by the use of this sulfonate resin of the present invention to provide a resist composition with high resolution, board depth of focus tolerance (DOF), small line edge roughness (LER) and high sensitivity. In the formula, Z represents a substituted or unsubstituted C1-C6 straight or branched alkylene group, or a divalent moiety in which substituted or unsubstituted C1-C6 straight or branched alkylene groups are bonded in series to a divalent group obtained by elimination of two hydrogen atoms from an alicyclic or aromatic hydrocarbon; R represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl or fluorine-containing alkyl group; and Q+ represents a sulfonium cation or an iodonium cation.
US08663894B1	Method to adjust the melt flow index of a toner Method of adjusting the melt flow index of a toner is described, the method including adjusting the pH of the toner after the toner particles have been coalesced and the adjusting alters the melt flow index of the toner.
US08663891B2	Toner for developing electrostatic latent image and method of preparing the same Disclosed are a toner for developing an electrostatic latent image and a method of preparing the same. The toner may include latex, a pigment and a releasing agent. The lowest crossover temperature of the toner at which the storage modulus (G′) and the loss modulus (G″) of the toner are substantially equal to each other may be in the range of about 65 to about 80° C. The weight average molecular weight (Mw) of the toner may be in the range of about 65,000 to about 75,000. The z-average molecular weight (Mz) of the toner may be in the range of about 110,000 to about 220,000.
US08663890B2	Electrostatic charge image developing toner and manufacturing method thereof, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method Provided is an electrostatic charge image developing toner, each toner particle including a core portion, a first shell layer, and a second shell layer, wherein the core portion contains a first polyester resin, a colorant, and a release agent, the first shell layer contains a second polyester resin and covers the core portion, the second shell layer contains a polymer of an aromatic vinyl monomer and a third polyester resin having an ethylenic unsaturated double bond that is polymerizable with the aromatic vinyl monomer, and covers the first shell layer, and a total amount of the first shell layer and the second shell layer is within a range of from 16% by weight to 40% by weight of the toner particle.
US08663889B2	Polyester resin for toner, toner, developer, toner cartridge, process cartridge, and image forming apparatus A polyester resin for a toner containing: a repeating unit derived from a dicarboxylic acid component; and a repeating unit derived from a dial component represented by Formula (1): wherein each of R1 and R2 independently represents a hydrogen atom or a methyl group, each of L1, L2 and L3 independently represents a divalent linking group selected from the group consisting of carbonyl groups, ester groups, ether groups, sulfonyl groups, substituted or unsubstituted chained alkylene groups, substituted or unsubstituted cyclic alkylene groups, substituted or unsubstituted arylene groups, and combinations thereof, L1 and L2 or L1 and L3 optionally forms a ring, each of A1 and A2 independently represents a rosin ester group, and the acid value is from 3 mgKOH/g to 30 mgKOH/g.
US08663888B2	Toner The present invention provides a toner including: a colorant, and a binder resin, wherein the toner is fixed on a recording medium using a fixing liquid containing a softening agent for softening the toner, and wherein a weight average molecular weight of a THF soluble fraction of the toner in a molecular weight distribution measured by gel permeation chromatography (GPC) is 3,000 to 8,300; and a glass transition temperature of the toner measured by differential scanning calorimetry (DSC) is 50° C. to 70° C.
US08663886B2	Toner compositions and processes The present disclosure provides polymeric additives for use with toner particles. The polymeric additive of the present disclosure includes a copolymer possessing at least one monomer having a high carbon to oxygen ratio, a monomer having more than one vinyl group, and at least one amine-functional monomer. Toners possessing this polymeric additive exhibit excellent stability with respect to relative humidity and excellent charging characteristics.
US08663885B2	Positively chargeable toner In a positively chargeable toner, calcium carbonate fine particles having a certain average primary particle diameter are attached to the surface of toner base particles. The toner base particles contain at least a binder resin and a colorant. The calcium carbonate fine particles are ones which had been subjected to a surface treatment with a positively chargeable surface treating agent and a silicone oil. A mass ratio of the positively chargeable surface treating agent to the silicone oil attached to the surface of the calcium carbonate fine particles is set to be 7:3 to 3:7 in terms of the positively chargeable surface treating agent:the silicone oil.
US08663884B2	Orange toner for developing electrostatic charge images An orange toner for developing electrostatic charge images includes a binder resin; and a colorant including a first color material and a second color material; wherein the first color material has a hue angle of −20° to 80° in a Lab* color system, the second color material includes C.I. Solvent Orange 63, and the second color material has a content of 0.05 to 0.2 parts by mass to 100 parts by mass of the binder resin.
US08663882B2	Electrophotographic photosensitive body, image-forming device using same and cartridge To provide an electrophotographic photoreceptor excellent in electric characteristics and various characteristics, capable of forming a uniform photosensitive layer and excellent in repetitive characteristics, an image forming apparatus using it and an electrophotgraphic cartridge.A lamination type electrophotographic photoreceptor comprising an electroconductive substrate and a photosensitive layer formed thereon, characterized in that the photosensitive layer contains a compound represented by the following formula (1), the ratio of the weight of the compound represented by the formula (1) to the weight content of all binder resins contained in the photosensitive layer is from 0.15 to 0.6, and the weight of the compound represented by the formula (1) is maximum among all charge transport materials: wherein each of Ar1, Ar2 and Ar3 is an aryl group which may have a substituent, each of Ar4 and Ar5 which are independent of each other, is an arylene group which may have a substituent, and each of n1 and n2 which are independent of each other, is an integer of from 1 to 3.
US08663881B2	Radiation source, method of controlling a radiation source, lithographic apparatus, and method for manufacturing a device A lithographic apparatus includes an illuminator for receiving a beam of EUV radiation from a radiation source apparatus and for conditioning the beam to illuminate a target area of a patterning device, such as a reticle. The reticle forms a patterned radiation beam. A projection system transfers the pattern from said patterning device to a substrate by EUV lithography. Sensors are provided for detecting a residual asymmetry in the conditioned beam as the beam approaches the reticle, particularly in a non-scanning direction. A feedback control signal is generated to adjust a parameter of said radiation source in response to detected asymmetry. The feedback is based on a ratio of intensities measured by two sensors at opposite ends of an illumination slit, and adjusts the timing of laser pulses generating an EUV-emitting plasma.
US08663875B2	Method of manufacturing a photomask A thin film composed of a material containing a metal and silicon is formed on a transparent substrate, and a thin film pattern is formed by patterning the thin film. Then, the main surface and the side walls of the thin film pattern are previously modified so as to prevent the transfer characteristics of the thin film pattern from changing more than predetermined even in the case where exposure light with a wavelength of 200 nm or less is cumulatively applied onto the thin film pattern which has been formed. The main surface and the side walls are modified by, for instance, performing heat treatment to the main surface and the side walls at 450-900° C. in the atmosphere containing oxygen.
US08663871B2	Resin composition for fuel cell separator, process for producing same, and fuel cell separator A fuel cell separator is produced by forming a fuel cell separator resin composition including, as essential components, (A) an epoxy resin; (B) a curing agent; (C) a curing accelerator; and (D) a carbon material, in which the content of the (D) is 50 to 85% by mass based on the total amount of the composition, in which the (D) includes high crystalline artificial graphite having an average particle size of 100 μm or more and less than 150 μm in an amount of 5 to 100% by mass based on the total amount of the (D), and in which the content of the (C) is 0.1 to 20 parts by weight per 100 parts by weight of the (B). The resin composition is excellent in electric conductivity and fluidity and contains little impurities, and can provide a fuel cell separator which is excellent in electric conductivity and dimensional accuracy, and has no fear of causing deterioration in performance of a solid electrolyte.
US08663867B2	Method of manufacturing a membrane electrode assembly, membrane electrode assembly and fuel cell The present invention provides an MEA which improves water retention properties of an electrode catalyst layer without inhibiting diffusion of a reaction gas and drainage of water produced by an electrode reaction etc. One aspect of the present invention is a manufacturing method of an MEA which includes coating and drying a catalyst ink to form a first electrode catalyst sub-layer, coating and drying a catalyst ink to form a second electrode catalyst sub-layer, and forming the first and the second electrode catalyst sub-layers on a polymer electrolyte membrane in this order, and has a specific feature that a solvent removal rate in drying to form the first electrode catalyst sub-layer is higher than that in drying to form the second electrode catalyst sub-layer.
US08663865B2	Method of manufacturing fuel cell, fuel cell manufacturing device, and fuel cell A method of manufacturing a fuel cell includes the steps of: (a) providing an extendable stacking reference member structured to extend and contract in a stacking direction; (b) arranging the stacking reference member in an extended setting via a first opening, such that one end of the stacking reference member is located inside a casing body and the other end of the stacking reference member is located outside the casing body; (c) after the step (b), mounting a plurality of cells of a cell laminate on the stacking reference member in a direction from inside to outside of the casing body; (d) contracting the stacking reference member and compressing the mounted cell laminate in the stacking direction, so as to locate the stacking reference member and the cell laminate inside the casing body of the fuel cell; and (e) after the step (d), attaching an end wall member to a first wall member to close the first opening and maintaining the cell laminate under a load in the stacking direction.
US08663863B2	Interconnect for a fuel cell, a method for manufacturing an interconnect for a fuel cell An interconnect for a fuel cell is made of pressed metal sheet. The interconnect integrates inlets and outlets, flow distributing inlet and outlet-zones seal surfaces and flow paths on both sides of the interconnect all formed and defined by discrete point or oblong protrusions made by the deformation of the sheet. A protrusion on one side of the interconnect corresponds to an indentation on the other side, but since the interconnect consists of three levels, the first side of the interconnect can be designed substantially independently of the second side.
US08663862B2	Fuel cell system An FC voltage increasing converter includes a plurality of converter parts having reactors. Regarding the first of the plurality of converter parts provided with a thermistor, the output starts to be limited when the temperature detected by the thermistor reaches a limitation starting temperature, which is obtained based on a reference heat-resistant temperature, which is obtained by subtracting an error of the thermistor from a specification heat-resistant temperature of each of the reactors. Meanwhile, regarding the second, third and fourth of the plurality of converter parts not provided with thermistors, the outputs start to be limited when the temperature detected by the thermistor reaches a limitation starting temperature obtained based on an allowable temperature, which is obtained by subtracting a characteristic-variation temperature of the reactor from the reference heat-resistant temperature of the reactor.
US08663856B2	Fuel cell stack A fuel cell stack is provided having a plurality of unit cells stacked in a horizontal direction. Each unit cell includes an electrolyte membrane having two surfaces and a peripheral edge, electrodes provided on both surfaces of the electrolyte membrane, frame-shaped members provided on both surfaces of the electrolyte membrane adjacent to the respective electrodes and adjacent the peripheral edge of the electrolyte membrane, separators provided on the electrodes and the frame-shaped members and having a reactant gas passage for supplying a reactant gas to each of the electrodes, and a manifold formed in the stacking direction in fluid communication with the reactant gas passage. The manifold includes a horizontal edge portion in fluid communication with the reactant gas passage.
US08663849B2	Metal halide coatings on lithium ion battery positive electrode materials and corresponding batteries Lithium ion battery positive electrode material are described that comprise an active composition comprising lithium metal oxide coated with an inorganic coating composition wherein the coating composition comprises a metal chloride, metal bromide, metal iodide, or combinations thereof. Desirable performance is observed for these coated materials. In particular, the non-fluoride metal halide coatings are useful for stabilizing lithium rich metal oxides.
US08663848B2	C2/m-structured cathode material for lithium-ion battery Disclosed is a C2/m-structured cathode material for a lithium-ion battery. The cathode material includes a lithium transition metal oxide represented by a formula of: Li(LiwNixCoyMnz)O2, wherein w+x+y+z=1, 0.42≦z≦0.60, 0.30≦x+y≦0.55, any of w, x, and y is larger than 0, and the cathode material having a single-phase structure with a space group of C2/m. A lithium-ion battery containing the C2/m-structured cathode material is also disclosed.
US08663846B2	Cathode active material, method of preparing the same, and cathode and lithium battery containing the material Composite cathode active materials having a large diameter active material and a small diameter active material are provided. The ratio of the average particle diameter of the large diameter active material to the average particle diameter of the small diameter active material ranges from about 6:1 to about 100:1. Mixing the large and small diameter active materials in a proper weight ratio improves packing density Additionally, including highly stable materials and highly conductive materials in the composite cathode active materials improves volume density, discharge capacity and high rate discharge capacity.
US08663843B2	Lithium secondary battery A lithium secondary battery (10) provided by the present invention has an iron oxide film-coated electrode employing a configuration in which an iron oxide film (144) capable of reversibly absorbing and desorbing lithium is retained on an electrically conductive base (142). The electrically conductive base (142) has a roughened surface having a surface roughness Rz of 3 μm or more, and the iron oxide film (144) is provided on the roughened surface.
US08663842B2	Silver positive electrode for alkaline storage batteries Silver positive electrode for alkali secondary batteries having an enhanced cycling capability, and consequently a longer lifetime in cycling of the storage batteries incorporating it, by optimizing, in recharge mode, the conditions for electrochemically reducing the oxidized silver species. The silver electrode according to the invention is of the plasticized type, and a high-porosity collector, such as a woven fabric, a felt or a reticulated cellular metal foam, is used. The active compound introduced into the collector is prepared in paste form, in which the active material consists of metallic silver particles and/or silver monoxide particles, and may advantageously include a metal oxide acting as pore-forming and wetting agent for the electrode. Such an electrode is particularly intended for mounting in silver-zinc storage batteries operating in open mode or sealed mode.
US08663841B2	Power storage device A power storage device in which charge capacity and discharge capacity are high and deterioration in battery characteristics due to charge/discharge is small is provided. A power storage device in which charge capacity and discharge capacity are high and output characteristics are excellent is provided. A power storage device in which charge capacity and discharge capacity are high and cycle characteristics are excellent is provided. A power storage device includes a negative electrode. The negative electrode includes a current collector, an active material including a plurality of protrusions protruding from the current collector and an outer shell in contact with and attached to surfaces of the plurality of protrusions, and graphene in contact with and attached to the outer shell. Axes of the plurality of protrusions are oriented in the same direction. A common portion may be provided between the current collector and the plurality of protrusions.
US08663840B2	Encapsulated sulfur cathode for lithium ion battery Methods of making a cathode element for an electrochemical cell. The methods comprise providing hollow carbon nanotubes and a sulfur source in a closed environment. Sulfur is deposited within an interior of the hollow carbon nanotube. The method includes cleaning an exterior surface of the carbon nanotubes and incorporating the carbon nanotubes into a cathode element. A cathodic material for a lithium-sulfur electrochemical cell is also provided. The material comprises a plurality of stacked-cone carbon nanotubes. Each nanotube defines a hollow interior and has a substantially continuous exterior surface area. Elemental sulfur is disposed within the hollow interior of each nanotube.
US08663834B2	Rechargeable battery pack and electrical hand tool device The invention relates to a rechargeable battery pack, in particular for an electrical hand tool device, comprising at least two series-connected rechargeable battery cells (20) and/or rechargeable batter cell blocks and an electronics unit having a printed circuit board (14), wherein sheet metal conductors (16) for electrically connecting the series-connected rechargeable battery cells (20) and/or rechargeable battery cell blocks are provided, wherein the sheet metal conductors (16) are connected directly to the printed circuit board (14).
US08663833B2	Bipolar secondary battery, battery assembly formed by connecting said batteries and vehicle mounting same Embodiments of a battery taught herein are directed to preventing a displacement between bipolar battery stacks or between a bipolar battery stack and an electrode tab. A bonding portion is formed at a part of a contact surface where a collector positioned at both ends in a stacking direction of a bipolar battery stack is bonded to the electrode tabs. The electrode tab and the collector are fixed by such a bonding portion. Further, the bonding portion is formed at a part of a contact surface where adjacent bipolar battery stacks are bonded to each other. Bipolar batteries positioned at upper and lower portions in the stacking direction are fixed by such a bonding portion.
US08663832B2	Cell for reducing short circuit and battery incorporating the cell Disclosed is a cell with a power-generating element and an outer package. The power-generating element includes a unit cell layer including a first electrode, a second electrode and an electrolyte layer disposed between the first and second electrodes. In the first electrode, a first collector is provided with one of a positive electrode active material layer and a negative electrode active material layer. In the second electrode, a second collector is provided with the other one of the positive and negative electrode active material layers. The first and second collectors have thicknesses such that when a conductor from outside penetrates at least two cells and a short circuit is formed between two cells via the conductor, shorted portions of the first and second collectors are fused by the heat generated by the current before the temperature of the cells reaches a predetermined value so that the short circuit is blocked.
US08663831B2	Rechargeable battery and its fabrication method A rechargeable battery and its fabrication method prevents electrical shorts between the electrode plates by decreasing shrinkage of the separator, the battery includes: an electrode assembly including: a wound electrode jelly roll having a first electrode plate with a first electrode tab attached thereto, a second electrode plate with a second electrode tab attached thereto and a separator interposed between the first electrode plate and the second electrode plate, and an upper tape arranged to surround an upper end of the electrode jelly roll where the first electrode tab and second electrode tab extend outward therefrom; a case having an upper end opening arranged to receive the electrode assembly and an electrolyte; and a cap assembly arranged to seal the upper end opening of the case after the electrode assembly has been received in the case; the upper tape is attached to the upper end of the electrode jelly roll and surrounds the separator adjacent to an end of an innermost electrode plate of the first and second electrode plates.
US08663829B2	Battery systems, battery modules, and method for cooling a battery module Battery systems, battery modules, and a method for cooling a battery module are provided. The battery module includes a first battery cell, and a first cooling fin having a first panel portion and first and second rail portions that are disposed on first and second ends, respectively, of the first panel portion. The first battery cell is disposed adjacent to a first side of the first panel portion. The first and second rail portions have a thickness greater than the first panel portion. The first cooling fin conducts heat energy from the first battery cell into the first cooling fin to cool the first battery cell. The battery module further includes first and second conduits extending through the first and second rail portions, respectively, that receive a fluid that flows through the first and second conduits to conduct heat energy from the first cooling fin into the fluid.
US08663827B2	Battery pack Provided is a battery pack, which can increase coupling force between a holder and a protection circuit board, and improve processability and productivity. The battery pack includes a bare cell, a holder disposed at one side of the bare cell and having a first fastening part, and a protection circuit assembly disposed at one side of the holder and having a second fastening part coupled to the first fastening part, wherein one of the first and second fastening parts is a protrusion and the other is a groove, and the protrusion includes a first supporting surface, a second supporting surface and a notch formed between the first and second supporting surfaces. Also, the battery pack includes a bare cell, a holder disposed at one side of the bare cell and having a first fastening part, and a protection circuit assembly disposed at one side of the holder and having a second fastening part coupled to the first fastening part, wherein the first fastening part is a first protrusion and the second fastening part is a second protrusion, and one of the first and second protrusions includes a first supporting surface, a second supporting surface and a notch formed between the first and second supporting surfaces and the other is formed in the shape of a square pillar.
US08663826B2	Battery assembly and fitting set thereof A fitting set, including a battery assembly and a receiver having a recess for receiving the battery assembly are disclosed. The battery assembly may include a casing having a top wall, a bottom wall, two first sidewalls, and two second sidewalls. The battery assembly may further include a resilient member and a self-locking block. The first sidewalls may include notches extending to the bottom wall. The recess may include lugs on one or more of the inners walls, each of which may be engaged with a corresponding notch. The second sidewalls may each include a first stopper and one or more second stoppers, the first and second stoppers having a difference in height. The resilient member at both ends may abut against the first stopper and self-locking block, respectively, and may also press the self-locking block against an edge of the recess.
US08663824B1	Battery pack exhaust nozzle utilizing an SMA seal retainer A thermal management system is provided that minimizes the effects of thermal runaway. The system includes a sealed battery pack enclosure configured to hold a plurality of batteries and at least one exhaust nozzle assembly. The exhaust nozzle assembly includes an exhaust nozzle that passes and directs the flow of hot gas from within the battery pack to the ambient environment during a thermal runaway event, a nozzle seal mounted within the exhaust nozzle that seals the exhaust nozzle during normal operation of the battery pack, and a shape memory alloy (SMA) retaining member that is configured to capture an end portion of the nozzle seal and hold the seal within the exhaust nozzle when the SMA retaining member is configured in its first shape, and that is configured to release the seal from the exhaust nozzle when the SMA retaining member is heated to its transformation temperature.
US08663821B2	Light-emitting material comprising multinuclear complexes Light emitting materials comprising multinuclear metal complexes comprising at least two metal atoms and a metal bridging ligand bound to said at least two metal atoms. It relates more particularly to a multinuclear complex of Formula (I): {-[L]2M-B-}n, wherein L is a bidentate ligand; M represents a transition metal having an atomic number of at least 40, and each M can be the same or different at each occurrence; B is a 2-connecting short metal bridging ligand bound to said at least two metal atoms, where the metal bridging ligand comprises coordinating atoms independently selected from the group consisting of nitrogen, phosphorous, carbon, oxygen, sulphur and selenium in 1,2 or 1,3 mutual position. (1,2-μ or 1,3-μ bonding mode); and n is an integer larger than 1.
US08663818B2	High corrosion resistance hot dip galvanized steel material The present invention provides a high corrosion resistance hot dip galvannealed steel material comprised of a Zn-based hot dip plated steel material achieving both a higher corrosion resistance of the plated layer itself by the added elements and sacrificial protection of iron metal by the plated layer or workability free of degradation caused of formation of intermetallic compounds by added elements, that is, a high corrosion resistance hot dip Zn plated steel material characterized in that an alloy plated layer containing Zn: 35 mass % or more, preferably 40 mass % or more, contains a non-equilibrium phase having a heat capacity by differential scanning calorimetry of 1 J/g or more. Furthermore, 5% or more, preferably 50% or more in terms of vol % is an amorphous phase. The alloy layer may contain, by mass %, Mg: 1 to 60% and Al: 0.07 to 59%, may further contain one or more elements selected from Cr, Mn, Fe, Co, Ni, and Cu in a total of 0.1 to 10%, and may in addition contain one or more elements of 0.1 to 10% of La, 0.1 to 10% of Ce, 0.1 to 10% of Ca, 0.1 to 10% of Sn, 0.005 to 2% of P, and 0.02 to 7% of Si.
US08663816B2	Hot-pressed member A hot-pressed member includes a steel sheet, a Ni-diffusion region present in a surface layer of the steel sheet, and an intermetallic compound layer and a ZnO layer which are provided in order on the Ni-diffusion region, the intermetallic compound layer corresponding to a γ phase present in a phase equilibrium diagram of a Zn—Ni alloy, wherein a spontaneous immersion potential indicated in a 0.5 M NaCl aqueous air-saturated solution at 25° C.±5° C. is −600 to −360 mV based on a standard hydrogen electrode.
US08663813B2	Seamless composite metal tube and method of manufacturing the same A seamless composite metal tube comprises an inner layer (1) consisting of copper or a copper alloy, an outer layer (5) consisting of aluminium or an aluminium alloy, and at least three different intermediate intermetallic layers (2, 3, 4) each consisting of copper and aluminium, wherein the concentration of copper decreases from the inner layer (1) to the outer layer (5) in the radial direction of the tube.
US08663810B2	Multilayer shrink films, labels made therefrom and use thereof A multilayer heat shrink film including a core layer including one or more alpha-olefin polymer and at least one skin layer including one or more cyclic olefin copolymers (COC), process for its preparation and uses thereof.
US08663809B2	Surface material substrate, surface material and molded body A surface material substrate has one surface of a fiber substrate containing cellulosic fiber is bonded with an acrylic resin binder containing a flame retardant and a thermosetting resin, a fineness of fiber constituting the fiber substrate is 2.2 dtex or less, and a mass ratio of the acrylic resin to the thermosetting resin is 80:20 to 65:35. A surface material is provided with an adhesive layer containing a resin with a melting point of 200° C. or less on a surface of the fiber substrate of the surface material substrate opposite to a facing surface, which is bonded with the acrylic binder. In a molded body, the surface material is integrated with a substrate mat by heat molding via an adhesive layer. The surface material substrate simultaneously fulfills requirements of low weight and cost, design properties, flame retardancy, mold releasability, followability and trimming properties.
US08663802B2	Substrate and method for fabricating the same A single crystal of zinc oxide which is c-axis oriented with use of electrolytic deposition method is formed on an amorphous carbon layer, after the amorphous carbon layer is provided on an inexpensive graphite substrate. The amorphous carbon layer is provided by oxidizing the surface of the graphite substrate.
US08663801B1	Organic-inorganic nanocomposite and polymer resin comprising the same The present invention relates to an organic-inorganic nanocomposite having orientation and a polymer resin comprising the same. An organic-inorganic nanocomposite according to the present invention includes inorganic nanoparticles each having one or more hydrogen bondable functional groups; first organic compounds each having two or more hydrogen bondable functional groups and one or more aromatic groups; and second organic compounds each having one or more hydrogen bondable functional groups and one or more aromatic groups, wherein the inorganic nanoparticle, the first organic compound and the second organic compound are bonded sequentially through hydrogen bonds, and the hydrogen-bonded inorganic nanoparticle, first organic compound and second organic compound, are laminated through π-π interaction to have orientation.
US08663799B2	Polypropylene based fibers and nonwovens The present invention relates to fibers and nonwovens made from plasticized polyolefin compositions comprising a polyolefin, a non-functionalized hydrocarbon plasticizer and a slip agent.
US08663798B2	Pressure-sensitive adhesive optical film and image display A pressure-sensitive adhesive optical film of the present invention comprises: an optical film comprising a transparent base film and an optical compensation liquid crystal layer provided on one side of the transparent base film; a pressure-sensitive adhesive layer provided on the optical compensation liquid crystal layer; and an undercoat layer that is interposed between the optical compensation liquid crystal layer and the pressure-sensitive adhesive layer and contains a polymer and an antioxidant. The pressure-sensitive adhesive optical film can suppress window frame unevenness when a backlight is turned on.
US08663795B2	Coated article and method for making same A process for coating articles is provided. The coated article includes a substrate, abase layer formed on the substrate; a chromium oxynitride layer formed on the base layer; and a silicon nitrogen layer formed on the chromium oxynitride layer. The chromium oxynitride layer and silicon nitride layer protect the substrate from oxidizing at high temperatures, extending the life of the coated article. A method for making the coated article is also described.
US08663792B2	Composite roofing overlay containing paint waste A composite roofing overlay containing paint waste is provided for use on a roof surface. The composite roofing overlay includes a bedding cement containing water-based paint waste and sand, a porous fabric embedded in the bedding cement, and at least one primer coat over the porous fabric and bedding cement. The composite roofing overlay may be used in combination with an overlying waterproof roofing membrane to provide an effective waterproof seal to new or existing roof structures.
US08663791B2	Composite reinforced cores and panels A composite core panel is produced by arranging a plurality of foam strips in adjacent relation and advancing the strips with one or two flexible sheets of porous reinforcement material and adhesive between platens to form a panel. The sheet on one side of the strips is folded between adjacent strips to form double wall pleats which may project either partially or fully between the strips and may have folded end portions overlying the other side of the strips. The second sheet may also form double wall pleats between the strips and be connected to the pleats in the first sheet. The core panel may be cut to form reinforced strips which are connected by adhesive in various arrangements to form other core panels. A core panel may also be formed by wrapping each foam strip longitudinally with a strip of reinforcing material and connecting the strips with adhesive.
US08663790B2	PE moulding composition for producing injection-molded screw cap closures and high-strength screw cap closure for carbonated beverages produced therewith The invention relates to a polyethylene molding composition having a multimodal molecular mass distribution and comprising a first ethylene homopolymer fraction (I), a second ethylene copolymer fraction (II) and a third ethylene copolymer fraction (III). The molding composition has a density at a temperature of 23° C. in the range from 0.945 to 0.953 g/cm3, an MFR (190° C./5 kg) in the range from 2 to 7 g/10 min and a viscosity number VN3 of the total mix of ethylene homopolymer fraction (I), copolymer fraction (II) and ethylene copolymer fraction (III), measured in accordance with ISO/R 1191 in decalin at a temperature of 135° C., in the range from 200 to 250 cm3/g. The invention further relates to the use of such a molding composition for producing high-strength injection-molded screw cap closures for bottles comprising beverages, especially carbonated beverages.
US08663786B2	Polyester film for optical application Disclosed is a polyester film for optical applications, and more specifically to a polyester film having refractive index of 1.6 to 1.7 and a film having refractive index of 1.4 to 1.6 on both surfaces of the polyester film, wherein a thickness of each coating layer is 0.03 to 0.1 μm and total light transmittance of the entire film is 93% or more. The polyester film according to the embodiment has total light transmittance higher than the polyester film without the coating layer and is more suitable to use the polyester film for optical applications due to the excellent adhesive strength between the polyester film and layer for the post-processing working.
US08663779B2	Formwork panel with frame containing an electronic identification element A shuttering element for producing concrete and reinforced concrete structures comprises a multi-layer panel and a frame element which at least partially surrounds the multi-layer panel and provides at least one identification element that can be contactlessly written on the read form. Methods for producing and repairing such shuttering elements are also provided.
US08663777B2	Aluminum-titanate-based ceramic honeycomb structure, its production method, and starting material powder for producing same A ceramic honeycomb structure having a large number of flow paths partitioned by porous cell walls, the cell walls comprising at least main crystals of aluminum titanate, in which MgO and SiO2 are dissolved to form a solid solution, and glass phases, the glass phases containing 40-80% by mass of SiO2 and 1-20% by mass of MgO, the average size of the glass phases being 30 μm or less in a cross section of the cell walls, and the area ratio of the glass phases to the total area of the main crystals of aluminum titanate and the glass phases being 2-12% in a cross section of the cell walls, and its production method.
US08663773B2	Vacuum insulation panel and method for manufacturing the same A vacuum insulation panel and to a method for manufacturing same. The method comprises: (a) a step of laminating a plurality of glass fiber boards to form a core, wherein the glass fiber boards are produced by a papermaking method using glass fiber dispersed in an inorganic binder; (b) a step of forming an outer cover having a structure in which a surface protection layer, a metal barrier layer, and an adhesive layer are laminated; (c) a step of producing a getter by packing quicklime (CaO) powder in a pouch; (d) a step of attaching the getter onto the core, or inserting the getter into the surface of the core; and (e) a step of forming the outer cover into a bag body, inserting the core from step (d) into the bag body, and sealing the bag body, thereby improving long-term durability of the vacuum insulation panel.
US08663772B2	Minute structure and information recording medium There is disclosed a minute structure including a sulfur compound and a silicon oxide. There is also disclosed a write-once information recording medium including a substrate and a recording layer formed of a mixed inorganic material and deposited on the substrate, wherein the mixed inorganic material contains a sulfur compound and a silicon oxide.
US08663767B2	Hollow profile used in the manufacture of a pipe A hollow profile used in the manufacture of a spirally wound double-walled thermo-plastic pipe, having essentially a rectangular cross section, two side walls and an outer wall and an inner wall limiting a cavity within. In the hollow profile the inner wall of the pipe is thicker than the wall of the hollow profile intended to form the outer wall of the pipe. The inner rounding radius of the edges adjacent to the thicker wall of the hollow profile is considerably larger than the rounding radius of the two other edges of the cavity and the inside surface of the thicker wall comprises a rib extending in the hollow cavity of the profile, on the side of the profile forming the inner side of the pipe, in the longitudinal direction of the profile at least essentially along the whole length of the profile.
US08663762B2	High-strength lightweight fabric for inflatable structures A high-strength, lightweight inflatable structure is formed of at least one flexible fabric member that, in an inflated condition, forms a self-supporting structure. The flexible fabric member is formed from a bare fabric having an areal weight of less than 4.5 oz/yd2. The fabric is coated with air-impervious resin coating comprising a polyurethane resin having a mixture of graphene nanoplatelets and a phosphorus-based flame retardant added thereto. The thermally exfoliated graphene nanoplatelets contain residual graphene oxide. Graphene oxide, which is a polar molecule, has an affinity for the polar molecules that make up the phosphorus based flame retardant. Accordingly, in addition to its inherent flame-retardant properties, the phosphorus based flame retardant acts as a dispersant to improve the uniform dispersion of the graphene nanoplatelets within the matrix, thus reducing or eliminating the need to use additional dispersants.
US08663761B2	Plastic preforms with marking for position detection A plastic preform, having a base body, a thread region arranged on the base body, wherein the thread region is formed in one piece with the base body, and a ring-shaped section which is arranged underneath the thread region, which extends outwards in a radial direction (R) of the plastic container and which is formed in one piece with the base body, wherein the ring-shaped section has a first surface facing the base body and a second surface facing the thread region. At least one optically perceivable marking is arranged on the surface facing the base body.
US08663757B2	Inkjet recording medium An inkjet recording medium includes a support and an ink-receiving layer which is disposed on the support and which contains an alumina pigment and an alkylsulfonic acid having the carbon number of 1 or more and 4 or less. The ink-receiving layer further contains a polymeric compound, a water-soluble zirconium compound, and boric acid or a borate. The polymeric compound is one obtained by cationizing at least one amino group of a product with acid, the product being obtained by the reaction of at least three compounds, that is, (i) a sulfur-containing organic compound containing two or more active hydrogen atoms, (ii) a polyisocyanate compound containing two or more isocyanate groups, and (iii) an amine compound containing two or more active hydrogen atoms.
US08663754B2	Pulsed laser micro-deposition pattern formation A method of forming patterns on transparent substrates using a pulsed laser is disclosed. Various embodiments include an ultrashort pulsed laser, a substrate that is transparent to the laser wavelength, and a target plate. The laser beam is guided through the transparent substrate and focused on the target surface. The target material is ablated by the laser and is deposited on the opposite substrate surface. A pattern, for example a gray scale image, is formed by scanning the laser beam relative to the target. Variations of the laser beam scan speed and scan line density control the material deposition and change the optical properties of the deposited patterns, creating a visual effect of gray scale. In some embodiments patterns may be formed on a portion of a microelectronic device during a fabrication process. In some embodiments high repetition rate picoseconds and nanosecond sources are configured to produce the patterns.
US08663753B2	High throughput multi-wafer epitaxial reactor An epitaxial reactor enabling simultaneous deposition of thin films on a multiplicity of wafers is disclosed. During deposition, a number of wafers are contained within a wafer sleeve comprising a number of wafer carrier plates spaced closely apart to minimize the process volume. Process gases flow preferentially into the interior volume of the wafer sleeve, which is heated by one or more lamp modules. Purge gases flow outside the wafer sleeve within a reactor chamber to minimize wall deposition. In addition, sequencing of the illumination of the individual lamps in the lamp module may further improve the linearity of variation in deposition rates within the wafer sleeve. To improve uniformity, the direction of process gas flow may be varied in a cross-flow configuration. Combining lamp sequencing with cross-flow processing in a multiple reactor system enables high throughput deposition with good film uniformities and efficient use of process gases.
US08663749B2	Method and device for producing polymer laminations or strand-shaped applications on a substrate A process and apparatus for the production of polymer layers or of strand-shaped applications on a substrate, in particular of FIPFG seals, by applying a reactive, foamable polymer material on the substrate, and the polymer material being subjected to a corona treatment or plasma treatment after it has been applied on the substrate.
US08663745B2	Film-forming method based on LB method Provided is a film-forming method based on an LB method by which a uniform alignment film using a helical polyacetylene can be obtained. The method based on the LB method includes: developing a helical polyacetylene onto a liquid surface; and transferring a monolayer film of the helical polyacetylene formed on the liquid surface onto a substrate to form a film, in which a compressibility P represented by the following formula (1) at a time of the film formation is 1×10−2 m/mN or less: P=(1/(dH/dS))×(1/S) (1), where H represents a surface pressure (mN/m) of the monolayer film of the helical polyacetylene, and S represents an area (m2) of the monolayer film of the helical polyacetylene developed onto the liquid surface.
US08663743B2	Release coating Described herein is the use of a modified PET in combination with a vinyl addition silicone water-based release coating to provide performance equivalent to the silicone by itself at a lower cost than the silicone by itself and resulting in a release backing paper that can be repulped and recycled in conventional recycled paper mills avoiding the additional cost of sending the scrap paper to landfill.
US08663741B2	Method for treating wheel rims and composition for use therein There is provided a method of treatment including (i) applying a treatment composition to at least a portion of the surface of a wheel rim and (ii) allowing a thus applied treatment composition to cure. There is also provided compounds and compositions useful in the method.
US08663736B2	Germanium complexes with amidine derivative ligand and process for preparing the same Provided is a germanium complex represented by Chemical Formula 1 wherein Y1 and Y2 are independently selected from R3, NR4R5 or OR6, and R1 through R6 independently represent (Ci-C7) alkyl. The provided germanium complex with an amidine derivative ligand is thermally stable, is highly volatile, and does not include halogen components. Therefore, it may be usefully used as a precursor to produce high-quality germanium thin film or germanium-containing compound thin film by metal organic chemical vapor deposition (MOCVD) or atomic layer deposition (ALD).
US08663731B2	Detachable framework used for winding optical fiber coil and a method of producing optical fiber coil A detachable framework used for winding optical fiber coils and a method of producing optical fiber coils with this framework. A framework with a suitable structure is designed considering comprehensively three factors, i.e., the window ratio of an optical fiber coil, the precision of an optical fiber gyro and the easy detachment of the framework from the optical fiber coil. A surface treatment with the framework is performed by coating a layer of thermosol on the surface of the framework so the optical fiber coil can be easily detached from the framework after curing. The required length of optical fiber is winded around the optical fiber coil framework, accompanying with vacuum pressure impregnating with curing adhesive after winding and optical fiber coil curing subsequently. The framework is taken off from the optical fiber coil under the heating circumstances, thereby completing production of the non-framework optical fiber coil.
US08663729B2	Pet food compositions Disclosed herein are pet food compositions. In one embodiment, pet food compositions which are described comprise a component selected from 2-deoxy-D-glucose; 5-thio-D-glucose; 3-O-methylglucose; 1,5-anhydro-D-glucitol; 2,5-anhydro-D-mannitol; mannoheptulose; and mixtures thereof. In yet another embodiment, pet food compositions which are described comprise an extract of plant matter selected from avocado, alfalfa, fig, primrose, and mixtures thereof. The pet food compositions may be prepared by any of a variety of processes including, but not limited to, optional processes described herein.
US08663725B2	Method for deriving a high-protein powder/ omega 3 oil and double distilled water from any kind of fish or animal ( protein) A method for deriving a protein powder from fish is presented. The method includes obtaining raw fish material and verifying the quality of the fish material. Solvents and concentrates are prepared and ground with the fish material to produce a mixture. The mixture placed in a reactor and baked. A first filtration of the mixture extracts solvents, concentrates, oil and water to produce a meal. The oil and water are separated to produce Omega 3 fish oil and water. The water is purified to produce purified water and the purified water is stored or bottled. A second filtration on the meal further extracts solvents and concentrates. The meal is ground to yield a fine texture and cured to produce the protein powder.
US08663723B2	Method for automated loading of food articles into containers The illustrative method and apparatus provides a more efficient system for automated slicing and loading of food articles into containers. The apparatus includes at least one cutting assembly and at least two chutes and depositing assemblies. The apparatus may include a positioning receptacle that aligns the food articles with a knife set and a driving arm that advances the food article into engagement with the knife set. The chutes may include a movable chute portion, which moves from alignment with the knife set to alignment with the containers, and a chute extension. Openings for the sliced food sections, which extend through the movable chute portion and the chute extension, have a cross section that changes to rotate the orientation of the food sections passing therethrough. Once deposited into the containers, the food sections are oriented with at least some cut faces of the food article adjacent the container wall.
US08663719B2	Herbal calf starter compositions The present invention relates generally to herbal calf starter compositions for feeding animals, particularly young animals, and methods of making them, and more particularly relates to shelf-stable and cheaper herbal calf starter compositions for overall development of calves to early complete functional maturity and also prevents any infection by acting as immunobooster. The herbal calf starter compositions comprise effective amount of a mixture of herbal extract and/or at least one bioactive fraction from medicinal herbs and one or more additives selected from Energy Source, Protein Source, Carbohydrate source, Chelated/organic Mineral Mixture, Vitamins, Salt, Toxin destroyer and Biocide. The invention also relates to processes for the preparation of such extracts and herbal calf starter compositions.
US08663717B2	Methods and delivery vehicles for providing throat relief A troche for providing throat relief. The troche includes a solid base containing pectin, food flavoring, aloe vera powder 200:1, malic acid, ginseng extract, natural glycerin, manuka honey, orchid extract, lysozyme, sorbitol crystals, and sorbitol base.
US08663716B2	Composition for treatment of aesthenopia This is to provide a novel medicine and a food and a drink composition for treating aesthenopia excellent in improved effect of aesthenopia.The composition for the treatment of aesthenopia comprises chondroitin sulfate or a salt thereof.
US08663714B2	Appetite regulating dietary supplement A dietary supplement for regulating the appetite of an individual is described. The dietary supplement comprises at least one mechanical satiety regulator, and at least one chemical satiety inducer, and may additionally comprise at least one thermogen, and/or at least one side effect remover. The dietary supplement induces satiety based on a combination of occupying part of the volume of the stomach, inducing sending signals to the brain in respect of satiety. Furthermore the dietary supplement may maintain or increase metabolism and reduce side effects such as the amount of produced flatulence. The dietary supplement may comprise fiber, whey, plant parts from plants e.g. of the genus Capsicum and plant parts from a species e.g. of the genus Mentha.
US08663713B2	Preparation, process and a regenerative method and technique for prevention, treatment and glycemic control of diabetes mellitus A medicinal preparation, a process, a nutritional composition and regenerative and insulin potentiating method for humans and also for mammals for prevention, treatment and management/glycemic control of diabetes mellitus by obtaining optimum glucose level in blood, by administering an extract of Costus pictus to produce above effect in a dose of 500-2000 mg/day in humans and 50-200 mg/kg/day in rats. A method for treating hyperglycemia in a patient by administering a medicinal preparation of Costus pictus D. Don. A method for long term management of diabetes by avoiding the problems associated with tight control of blood glucose concentrations, i.e., hypoglycemia tolerance and seizures, while simultaneously avoiding the problems associated with conventional moderate control of blood glucose concentrations, i.e., pathological complications associated with hyperglycemia, such as nephropathy, retinopathy, etc. The medicinal preparation further affords an insulin potentiating action in addition to decreasing blood glucose and/or glycosylated hemoglobin levels.
US08663711B2	Use of armillaridin for treating cancer Novel Uses of an aromatic ester isolated from Armillaria mellea, particularly, armillaridin, are disclosed herein. The armillaridin is useful for manufacturing a medicament or a pharmaceutical composition for suppressing the growth of cancerous cells or for enhancing susceptibility of esophageal cancerous cells to a radiation treatment, in a subject.
US08663706B2	Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08663704B2	Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans A composition and method which improves blood lipid profiles and optionally reduces low density lipoprotein (LDL) per-oxidation in humans by administering a therapeutic amount of a composition comprising krill oil in combination with astaxanthin or a mixture of fish oil derived, choline based, phospholipid bound omega-3 fatty acid mixture including phospholipid bound polyunsaturated EPA and DHA. In one embodiment, the krill oil is derived from Euphasia spp., comprising Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) fatty acids in the form of triacylglycerides and phospholipids. The krill oil includes at least 10% EPA and 5% DHA, of which greater than 50% are in the form of phospholipids and the 1-4000 mg of krill oil per daily dose is delivered.
US08663700B2	Drug loaded polymeric nanoparticles and methods of making and using same The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol.
US08663694B2	Taste masked dosage form containing roflumilast Taste masked dosage forms for oral administration of roflumilast are described.
US08663691B2	Gel composition for shower filter, method for manufacturing shower gel filter and shower filter Provided are a gel composition for a shower filter with viscosity restorability, a method for manufacturing a shower gel filter and a shower filter. More particularly, the gel composition for a shower filter includes dextrin, a fragrance, water and a water-soluble cellulose ether, and may further include vitamin C intended to remove residual chlorine and harmful substances contained in water, and a food coloring intended to allow the users to identify a particular type of fragrance.
US08663688B2	Semi-solid mucoadhesive formulations Semisolid mucoadhesive formulations for vaginal application, with improved technical and organoleptic characteristics, which contain at least two bioadhesive gelling polymers and an active ingredient, useful in the prevention and/or treatment of various pathologies and disorders in human beings or animals.
US08663685B2	Sustained release aminopyridine composition A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.
US08663682B2	Taste-masking coated particles, process for the preparation thereof and orodispersible tablets containing said coated particles The present invention relates to a coated particle of active substance comprising a core, said core comprising the active substance and an acidic compound, said core being coated with a taste masking coating based on a polymer which is soluble at pH of 5 or less, and which is permeable at pH above 5.
US08663679B2	Compositions for improving breast health in women Disclosed are compositions and corresponding methods for treating fibrocystic breast disease or other breast-related disease or condition. The compositions comprise, per serving or dose, from zero to about 400 μg selenium, from about 100 mg to about 6000 mg gamma linolenic acid, and about 0.15 mg to about 5 mg iodine, with nutritional embodiments further comprising one or more of protein, fat, carbohydrate, vitamins, and minerals and providing from about 50 to about 1000 kcal of energy per severing or dose. Also disclosed are in-vitro studies showing that certain combinations of gamma linolenic acid, iodine, and/or selenium may 1) inhibit breast cancer or fibrocystic cell proliferation, 2) reinforce the function of tight junctions of endothelial cells and of mammary epithelial cells in estrogen-sensitive conditions, and 3) reduce the risk of vascular invasion by breast cancer cells.
US08663676B2	Dehydrated granular composition and biomedical applications thereof The invention relates to a granular composition for a biomaterial, that comprises from 0.1 to 5 wt % of at least one polymer derived from cellulose, 75 to 99.9 wt % of a mineral phase containing hydroxyapatite and/or β tricalcic phosphate, and 0 to 10 wt % of water, preferably 0 to 7 wt % of water, more preferably 0 to 5 wt % of water, and even more preferably approximately 5 wt % of water.
US08663675B2	Injectable matrix having a polymer and a stem cell niche composed of cup-shaped nanoparticles containing growth factors or physiological agents for organ reconstruction The various embodiments herein relate to an injectable matrix used for regeneration, reconstruction, repair or replacement of organ or tissue. The injectable matrix consists of a synthetic and natural polymer, a stem cell niche and nanoparticles in the form of cups filled with growth factor and physiologic agent. The embodiments herein also provide a method for regeneration, reconstruction, repair or replacement of organ or tissue. In the method, an injectable matrix is injected to create three dimensional matrix system or network in an area of the desired tissue or organ, migration of blood circulatory stem cells or tissue-specific progenitor cells occur to the injected area of the tissue or organ. The growth factors and physiological agent present in the nanocups are released. The stem cells proliferate and differentiate to form the desired organ or tissue.
US08663674B2	Microparticle containing matrices for drug delivery Polymeric matrices including microparticles that provide sustained release of a hydrophilic bioactive agent are described. The matrices can be in the form of a coating on the surface of an implantable medical article or an in situ formed matrix. The microparticles of the matrix include a first polymer and a second polymer that modulates release of the hydrophilic bioactive agent from the matrix.
US08663669B2	Pesticide treatment of soils or substrates with sulphur compounds In order to replace methyl bromide in all the uses thereof in soil or substrate treatment, the invention relates to the use of at least one sulphur compound having general formula: wherein R represents an alkenyl or alkyl radical, n is equal to 0, 1 or 2, x is a number between 0 and 4 and R′ represents an alkenyl or alkyl radical or, only if n=x=0, a hydrogen or alkali-metal atom. The sulphur compounds (in particular dimethyldisulphide) can be applied according to standard soil treatment methods (by injection, spraying, dripping, sprinkling) and said compounds have no phototoxic effects.
US08663668B2	Preservative for medical devices The invention relates to the field of disinfection and preservation of surfaces of medical devices. The object of the invention is to make available a disinfectant that provides effective decontamination of medical devices while at the same time being toxicologically safe. This object is achieved through the use of solution containing biguanide. Additional advantages of using such solutions include the fact that the active ingredient used for preservation can be completely rinsed out prior to use and does not have a negative effect on the functionality of protein-containing medical devices. The thoroughness of the rinsing operation can be verified by means of a spectroscopically active additive.
US08663666B2	Water based liquid makeup cosmetic Provided is a water based liquid makeup cosmetic which is filled in an applicator for a liquid cosmetic equipped with a brush-like coating part to be suitably used for making up, particularly a water based liquid makeup cosmetic which is suited for making up around eyes, and in order to obtain the cosmetic, assumed is a formation comprising at least a tabular pigment, a pigment dispersant, a coating film-forming agent, 0.001 to 0.5 mass % of a surfactant and water and further comprising a spherical powder.According to the formation for a water based liquid makeup cosmetic, obtained is a water based liquid makeup cosmetic which makes it easy to rehomogenize (redisperse) the cosmetic by slightly shaking even after turned into an uneven state with standing still during storage and which makes fine lines liable to be drawn and is excellent in a water resistant fixing performance.
US08663664B2	Temperature sensitive state-changing hydrogel composition and method for their preparation The object of this invention is to provide a temperature-sensitive state-changing hydrogel composition and a method of producing the same. The hydrogel composition includes 1-10 wt % of branched gelation polymer, 0.5 5 wt % of electrolyte gelation polymer, 0.5-5 wt % of skin-communication enhancer, 1-10 wt % of natural biomaterial, 3-30 wt % of polyhydric alcohol, 1-10 wt % of functional additive, and 30-93 wt % of water based on a total weight of the composition. Hydrogel is transformed into a fluid state at 10-50° C. The hydrogel composition is transformed into a fluid state due to body temperature when it comes into contact with the skin to be fluidized, so that cosmetics or drugs contained in hydrogel are uniformly and quickly delivered into the skin.
US08663658B2	Revaprazan-containing solid dispersion and process for the preparation thereof The present invention provides a solid dispersion in which revaprazan particles are surface-modified with a water-soluble polymer, a water-soluble saccharide, a surfactant, or a mixture thereof and a process for preparing the same. The present invention also provides a pharmaceutical composition containing the solid dispersion and a process for preparing the pharmaceutical composition.
US08663656B2	Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages A small number of defined antigens can provide broad protection against meningococcal infection, and the invention provides a composition which, after administration to a subject, is able to induce an antibody response in that subject, wherein the antibody response is bactericidal against two or three of hypervirulent lineages A4, ET 5 and lineage 3 of N. meningitidis serogroup B. Rather than consisting of a single antigen, the composition comprises a mixture of 10 or fewer purified antigens, and should not include complex or undefined mixtures of antigens such as outer membrane vesicles. Five protein antigens are used in particular: (1) a ‘NadA’ protein; (2) a ‘741’ protein; (3) a ‘936’ protein; (4) a ‘953’ protein; and (5) a ‘287’ protein.
US08663652B2	Regeneration of endogenous myocardial tissue This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject a composition comprising an amount of a human stromal derived factor-1 and an amount of a human granulocyte-colony stimulating factor, the composition being administered in an amount effective to cause proliferation of cardiomyocytes within the subject's heart so as to thereby treat the disorder. This invention also provides a method of treating a subject suffering from a disorder of a tissue involving loss and/or apoptosis of cells of the tissue which comprises administering to the subject a composition comprising an amount of an agent which induces phosphorylation and/or activation of protein kinase B, or an agent which induces phosphorylation and/or activation of an extracellular signal-regulated protein kinase, or an agent which induces activation of CXCR4.
US08663649B2	Diagnosis and treatment of Trypanosoma cruzi infection and Chagas disease Provided herein are vaccine compositions for control of Trypanosoma cruzi infection and Chagas disease. The compositions comprise plasmids encoding o GPI-anchored genes ASP-2, TcG-1, TcG2 and TcG4 from Trypanosoma cruzi; plasmids encoding cytokines IL12 and GM-CSF; and plasmids encoding a gene expression system. Certain vaccine compositions comprise recombinant proteins, selected from TcG-1, TcG2 and TcG4 from Trypanosoma cruzi. In another vaccination strategy, the recombinant proteins are replaced by lysates comprising Trypanosoma rangeli cells. Further provided herein are diagnosis compositions comprising 1) recombinant proteins, selected from TcG-1, TcG2 and TcG4 from Trypanosoma cruzi; 2) antibodies that specifically binds the TcG-1, TcG2 and TcG4 proteins; 3) sense and antisense polynucleotide sequences that encode the TcG-1, TcG2 and TcG4 proteins. Said compositions can be used in diagnosing and/or evaluating efficacy of treatments against Trypanosoma cruzi infection. A diagnosis kit, and methods of diagnosing and/or treating Trypanosoma cruzi infection are also provided.
US08663648B2	Agents for treatment of HCV and methods of use An amphipathic helix at the approximate N-terminus of Hepatitis C virus (HCV) nonstructural proteins mediates the association of these proteins with cytoplasmic membranes in infected cells. This association is essential for replication. Thus, assessing the ability of compounds or protocols to disrupt the association of such helices with cytoplasmic membranes permits identification of compounds and protocols which are useful in the treatment of HCV infection. Also useful in the invention are mimics, or function-disrupting ligands, of an amphipathic helix of the nonstructural proteins described herein and antibodies and fragments thereof immunoreactive with said helix.
US08663647B2	Epitope peptides derived from vascular endothelial growth factor receptor 1 and vaccines containing these peptides The present invention provides immunogenic peptides comprising the amino acid sequence of SEQ ID NO: 1, 2, 13, 32, and peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for treating or preventing tumors comprising these peptides. The peptides of this invention can be used as vaccines.
US08663646B2	P53 peptide vaccine The invention relates to a peptide derived from p53 that could be used as a vaccine against cancer.
US08663643B2	Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use Combinations of the antibody-drug conjugate trastuzumab-MCC-DM1 and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by HER2 and KDR (VEGFR receptor 1). Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
US08663637B2	Methods and compositions for modulation of Olfml3 mediated angiogenesis The present invention relates to antibodies against specific domains of Olfml3 and the use of such in angiogenesis. In particular aspects, angiogenesis-related conditions, such as cancer, can be treated by the composition comprising the Olfml3 antagonists.
US08663635B2	N-cadherin: target for cancer diagnosis and therapy The present invention provides methods of diagnosis, providing a prognosis and a therapeutic target for the treatment of cancers that express N-cadherin, including prostrate and bladder cancers.
US08663634B2	Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity The present invention provides methods of treating, preventing or ameliorating the symptoms of T cell-mediated immunological diseases, particularly autoimmune diseases, through the use of anti-CD3 antibodies. In particular, the methods of the invention provide for administration of antibodies that specifically bind the epsilon subunit within the human CD3 complex. Such antibodies modulate the T cell receptor/alloantigen interaction and, thus, regulate the T cell mediated cytotoxicity associated with autoimmune disorders. Additionally, the invention provides for modification of the anti-CD3 antibodies such that they exhibit reduced or eliminated effector function and T cell activation as compared to non-modified anti-CD3 antibodies.
US08663631B2	Methods for treating lysosomal acid lipase deficiency in patients The present invention provides methods of treating LAL deficiency comprising administering to a mammal a therapeutically effective amount of lysosomal acid lipase with an effective dosage frequency. Methods of improving growth and liver function, increasing LAL tissue concentration, and increasing LAL activity in a human patient suffering from LAL deficiency are also provided.
US08663630B2	Promotion of peroxisomal catalase function in cells The molecular mechanisms of peroxisome biogenesis have begun to emerge; in contrast, relatively little is known about how the organelle functions as cells age. The present inventors characterized age-related changes in peroxisomes of human cells and showed that aging compromises peroxisomal targeting signal 1 (PTS1) protein import, with the critical antioxidant enzyme, catalase, especially affected. The number and appearance of peroxisomes are altered in these cells, and the organelles accumulate the PTS1-import receptor, Pex5p, on their membranes. Concomitantly, cells produce increasing amounts of the toxic metabolite, H2O2, and this increased load of reactive oxygen species (ROS) may further reduce peroxisomal protein import and exacerbate the effects of aging. Disclosed are novel compositions and methods for restoring catalase in peroxisomes by use of targeted catalase modified at its C-terminus and/or N-terminus, optionally in combination with polypeptides which promote cellular uptake of proteins, to prevent or overcome the changes that follows aging or that are associated with a number of diseases or disorders.
US08663629B2	Kallikrein-binding “kunitz domain” proteins and analogues thereof This invention provides: novel protein homologous of a Kunitz domain, which are capable of binding kallikrein; polynucleotides that encode such novel proteins; and vectors and transformed host cells containing these polynucleotides.
US08663628B2	Solid phase glycerolysis An enzymatic solid phase reaction for preparing a solid having greater than 40% monoglyceride from a reaction mixture; wherein the reaction mixture comprises: (i) lipase; (ii) at least 14 weight % glycerol; and (iii) glyceride; and optionally (iv) lecithin; such that if (iv) is not present then the glyceride (iii) has an iodine value of between about 5 and about 35, and a solid fat content of more than about 75% at 20° C. The present invention further relates to a process of preparing an enzymatic solid phase reaction mixture for preparing a solid having greater than 40% monoglyceride.
US08663626B2	Vascularized islets and methods of producing same An isolated composition of matter is provided comprising a heterogeneous population of cells seeded on a surface of a scaffold, wherein the heterogeneous population of cells comprises at least one pancreatic islet, endothelial cells and fibroblast cells. Methods of generating same and uses thereof are also provided.
US08663624B2	Adeno-associated virus virions with variant capsid and methods of use thereof The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
US08663617B2	Wound healing peptides and methods of use thereof The current invention relates to methods and compositions for the treatment of wounds in a mammalian subject. Particularly, the invention relates to novel polypeptides and encoding nucleic acids that stimulate keratinocyte and endothelial cell motility and/or proliferation.
US08663616B2	Enzymatic peracid generation for use in oral care products Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
US08663608B2	Hydroxytyrosol compounds A hydroxytyrosol polymer formed by either C—C coupling or C—O—C coupling is provided. Preferred polymers are formed by C—C coupling and the dimer has the following structure: Compounds of the invention have been found to have antioxidant properties and their use in antioxidant compositions forms a further aspect of the invention.
US08663607B2	Ferrate(VI)-containing compositions and methods of using ferrate(VI) Compositions containing ferrate(VI) are disclosed. Also, methods are disclosed that utilize ferrate(VI).
US08663605B2	Agent for fibers containing keratin, comprising at least one specific amphiphilic cationic polymer, at least one cationic styling polymer that is different therefrom and at least one film-forming non-ionic and/or stabilizing non-ionic polymer Agent for treating fibers containing keratin, in particular human hair, having in a cosmetically acceptable carrier, (a) at least one amphiphilic, cationic polymer comprising at least one structural unit of formulae (I) to (IV), wherein R1 and R4 are independently hydrogen or a methyl group; X1 and X2 are independently oxygen or a NH group; A1 and A2 are independently ethane-1,2-diyl, propane-1,3-diyl or butane-1,4-diyl; R2, R3, R5 and R6 are independently a (C1 to C4)-alkyl group; R7 is a (C8 to C30)-alkyl group; (b) at least one other film-forming cationic and/or stabilizing cationic polymer; and (c) at least one film-forming non-ionic and/or stabilizing non-ionic polymer. The invention also relates to the use of the agent for temporarily styling hair and for haircare, particularly as an aerosol hairspray or aerosol mousse.
US08663604B2	Method for measuring neurotransmitters in vivo A method is provided for in vivo detection of a biochemical substance in an animal by culturing neurofluocytes that stably express a receptor of the biochemical substances by transfecting cells with cDNA of the receptor and a tag that will emit a detectable energy in the presence of the biochemical substance, implanting the neurofluocyte into the animal's brain; and detecting the energy emission of the tag. In a first embodiment, the biochemical substance is a neurotransmitter, the tag is a fluophore, and the step of detecting includes forming an opening in the animal's skull and optically detecting fluorescent emissions using a two-photon laser scanning microscope. Multiple biochemical substances can be simultaneously detected by culturing neurofluocytes that express different receptors and have different fluophor tags that produce fluorescent signals at distinguishable wavelengths.
US08663600B2	Diagnosis of prostate cancer Methods for diagnosing prostate cancer, and differentiate prostate cancer from other prostate complications, and use of said method, and diagnosing and monitoring lymph gland metastasis, post operative examinations, and examinations during or after radiation, cytostatic, and androgen treatments are disclosed. The methods comprise injecting tracer-labelled PSA or hK2 specific antibodies, visualising PSA or hK2 producing tissue with the aid of a visualization method, and diagnosing prostate cancer from the difference in visualization.
US08663596B2	Reactor, a structure packing, and a method for improving oxidation of hydrogen sulfide or polysulfides in liquid sulfur Disclosed is a reactor, a structured packing, and a method for increasing the rate of decomposition of polysulfides and oxidation of polysulfides and hydrogen sulfide in liquid sulfur. The reactor, the structured packing, and the method involve a structured packing for contacting a first stream and a second stream in a reactor including a catalyst. The catalyst increases the rate of decomposition of polysulfides and oxidation of polysulfides and hydrogen sulfide in the liquid sulfur of the first stream with the second stream. The first stream includes liquid sulfur containing polysulfides and dissolved hydrogen sulfide. The second stream includes an oxygen-containing gas.
US08663591B2	Method of preparing graphene shell and graphene shell prepared using the method Provided are a method of preparing a graphene shell and a graphene shell prepared using the method. A first heat treatment is performed on a mixture of an organic solvent and a graphitization catalyst so as to carburize the graphitization catalyst with carbon decomposed from the organic solvent. The graphitization catalyst is in the form of particles. A second heat treatment process is performed on the carburized graphitization catalyst in an inert or reductive gas atmosphere to thereby form graphene shells on surfaces of the carburized graphitization catalyst.
US08663589B2	CO2 recovery using the sure process The invention relates to a method for recovering sulphur from a sour gas containing hydrogen sulphide and carbon dioxide, comprising: oxidation of the sour gas, wherein a part of the hydrogen sulphide is oxidized to sulphur dioxide and water, reaction of the resulting sulphur dioxide with the residual hydrogen sulphide to elementary sulphur, and removal of elementary sulphur. According to the invention carbon dioxide and/or carbon dioxide generated by oxidation of the sour gas is compressed, and at least a part of the carbon dioxide is injected into an oil well. Furthermore, the invention relates to a plant suitable for performing the above method.
US08663587B2	Catalyzed soot filter and emissions treatment systems and methods Catalysts, catalytic articles, and catalyst systems and methods for treating exhaust gas streams utilizing the catalytic articles are described. In one or more embodiments, a catalytic article includes a first SCR catalyst permeating the porous walls of a substrate and a second SCR catalyst coating the walls of the substrate. Methods for treating an exhaust gas stream are also provided. Methods of making and using such catalysts and catalytic articles are also described.
US08663580B2	Dried biological fluid spot punch device and related methods A dried biological fluid spot punch device includes a tube, a frit, and a filter disposed on the frit. The tube includes a main section and a distal section adjoining the main section. The main section includes a proximal tube end circumscribing a proximal tube opening, and the distal section includes a distal tube end circumscribing a distal tube opening. The distal section further includes a distal tube having a tapered inside diameter that reduces from the main section to the distal tube opening. The frit is disposed in the distal section at a distance from the distal tube opening and fixed in position by frictional contact with the distal tube wall. The punch device may also include a punching tool. The punching tool may include a body engaging the tube at the proximal tube end and an ejection mechanism configured for disengaging the body from the tube.
US08663576B2	Detection of intraamniotic infection The present invention concerns the identification of biomarkers and groups or combinations of biomarkers that can be used for non-invasive diagnosis of intra-amniotic infection, and diagnostic assays using such biomarkers.
US08663575B2	Sample holder for dynamic light scattering There is described a sample holder and associated fluid container assembly for optical analysis of a fluid sample within a translucent container of the fluid container assembly. The sample holder includes clamping members rotatably mounted to a frame for rotation, about parallel axes spaced apart from each other, between a container accepting position in which the clamping members are spaced apart from the translucent container, and an analysis position in the clamping members abut the translucent container. The clamping members each define an optical waveguide slot extending therethrough that is substantially aligned with the translucent container when the clamping members are disposed in the analysis position, to thereby provide optical access to the translucent container for optical analysis of the fluid sample therein.
US08663572B2	Micro plasma jet generator The present invention provides a microplasma jet generator capable of stably generating a microplasma jet in a microspace at atmospheric pressure with low electric power.The microplasma jet generator is driven with a VHF power supply to generate an inductively coupled microplasma jet and includes a substrate, a micro-antenna disposed on the substrate, and a discharge tube located close to the micro-antenna. The micro-antenna has a flat meandering shape with plural turns.
US08663571B2	Method and apparatus for making uniform and ultrasmall nanoparticles A system comprising: a plasma production chamber configured to produce a plasma; a reaction chamber vaporize a precursor material with the plasma to form a reactive mixture; a quench chamber having a frusto-conical surface and a quench region formed within the quench chamber between an ejection port of the reaction chamber and a cooled mixture outlet, wherein the quench region configured to receive the reactive mixture from the ejection port, to cool the reactive mixture to form a cooled mixture, and to supply the cooled mixture to the cooled mixture outlet; and a conditioning fluid injection ring disposed at the ejection port and configured to flow a conditioning fluid directly into the reactive mixture as the reactive mixture flows through the ejection port, thereby disturbing the flow of the reactive mixture, creating turbulence within the quench region and cooling the reactive mixture to form a cooled mixture comprising condensed nanoparticles.
US08663570B2	Sterilizing apparatus and ion generating apparatus A sterilizing apparatus and an ion generating apparatus, which generate sufficient amount of cations in a short period of time and also maintain the amount of ions generated at a level that is harmless to the human body. The sterilizing apparatus and the ion generating apparatus optimize the position of an electrode to maximize the generation of active hydrogen. The ion generating apparatus includes a first electrode for generating hydrogen ions and a second electrode located such that the second electrode is separated from the first electrode by a designated distance for generating electrons and superoxide anions. The hydrogen ions generated from the first electrode react with the electrons generated from the second electrode to produce hydrogen atoms, and the hydrogen atoms react with the superoxide anions generated from the second electrode to sterilize the air.
US08663568B2	Apparatus and system for handling photocurable fluid waste An apparatus for disposal of photocurable fluid waste may include a conduit for conducting photocurable fluid waste from a source of photocurable fluid waste; a dispenser for automatically dispensing a receptacle made of material that is impermeable to the photocurable fluid waste and that transmits radiation capable of curing; a welder or other sealing device for welding the receptacle to form a bag with a portion of the photocurable fluid waste inside; and a source of radiation for curing the photocurable fluid waste in the bag.
US08663564B2	Sequestration of carbon dioxide using metal oxides Embodiments of the present invention relate to carbon dioxide sequestration systems and methods. In an embodiment, the invention includes a method of sequestering carbon dioxide. The method can include mixing carbon dioxide with an alcohol to form a reaction mixture and contacting the reaction mixture with a metal oxide catalyst under reaction conditions sufficient to produce a carbonate as a reaction product. In an embodiment, the invention includes a carbon dioxide sequestration system. The system can include a carbon dioxide supply source, an alcohol supply source, and a reaction vessel. A metal oxide catalyst can be disposed within the reaction vessel. The system can be configured to mix carbon dioxide from the carbon dioxide supply source with an alcohol from the alcohol supply source to form a reaction mixture and contact the reaction mixture with the metal oxide catalyst. Other embodiments are also described herein.
US08663562B2	Flow cell for measuring electromagnetic radiation absorption spectra in a continuously flowing immiscible liquid(s) or liquids with entrained gas phases An apparatus and method for spectral analysis of immiscible phases are disclosed. A flow cell for online absorption measurements of immiscible process phases can comprise: a body containing an inlet window and an outlet window in operable communication with a measurement instrument; and a series of partitions that divide the inside of the flow cell into three (3) or more vessels that have an inlet and an outlet, wherein the vessels are connected in series with one another. Optionally, the first vessel is equipped with a porous membrane to facilitate the separation of immiscible process phases.
US08663560B2	Flow cell and liquid delivery method A flow cell includes: a flow channel through which a sample solution flows; an inlet section which communicates with the flow channel and to which the sample solution is supplied; a transfer section which includes a plurality of opening sections, one end side of which communicates with the flow channel and an other side of which opens to outside air, and which communicates with the flow channel, and draws in and guides the sample solution supplied into the inlet section to the flow channel; a detecting section which faces the sample solution in the flow channel; and a sealing member which unsealably seals at least either one of the opening section or the inlet section.
US08663559B2	Sample analyzer, sample analyzing method, and computer program product A sample analyzer that includes a sample preparing section operative to aspirate a sample from a sample container and a measuring section operative to prepare a plurality of measurement samples from the aspirated sample. A control unit is configured to sequentially measure the plurality of prepared measurement samples, obtain a plurality of measurement data for the respective measurement samples, and obtain an analysis result of a predetermined item of the sample based on the plurality of measurement data.
US08663557B2	Analyzer An analyzers that comprise a container holder for placing containers; a detector for detecting whether or not a container is placed at the container holder; a controller for acquiring the status of the container holder based on the output of the detector; and a display for displaying the status of the container holder is disclosed.
US08663554B2	Method for fabricating a biosensor chip and the biosensor chip made thereby A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
US08663551B1	Animal containment facility ventilation system The containment facility ventilation system comprises a two stage scrubber configuration. Exhaust air flows out of an animal containment facility and into a particulate scrubber, which removes particulates and reduces the alkalinity of the exhaust air. The particulate scrubber also reduces the carbon dioxide in the exhaust air. The air then flows into a chemical scrubber which effectively removes ammonia from the exhaust air. The chemical scrubber comprises a potassium bisulfate scrubber solution, and the particulate scrubber comprises a neutral calcium salt scrubber solution.
US08663549B2	Heat-resisting steel for engine valves excellent in high-temperature strength To provide an inexpensive heat-resisting steel for engine valves by causing Fe-based heat-resisting steel to exhibit high temperature strength not inferior to that of Ni-based heat-resisting steel. A heat-resisting steel for engine valves excellent in high temperature strength containing, in % by mass, C: 0.20 to 0.50%, Si: 1.0% or less, Mn: 5.0% or less, P: 0.1 to 0.5%, Ni: 8.0 to 15.0%, Cr: 16.0 to 25.0%, Mo: 2.0% or less (including 0%), Cu: 0.5% or less, Nb: 1.0% or less (including 0%), W: 2.0% or less (including 0%), N: 0.02 to 0.30%, B: 0.01% or less, and remnants of Fe and impurities, wherein the heat-resisting steel for engine valves satisfies formulae below: 156.42P(%)+0.91Mo(%)+0.73W(%)−12.27Nb(%)+220.96N(%)+120.59≧170 Formula (1) 13.70P(%)−6.97Mo(%)−4.32W(%)−3.29Nb(%)+119.10N(%)+27.75≧25 Formula (2).
US08663547B2	High pressure heat treatment system A furnace for heat treating a metal workpiece is provided. A method and system for processing a workpiece also are provided.
US08663546B2	Cellular ceramics apparatus and methods of production Cellular ceramic materials, for example closed cell glass ceramic materials, for use in construction of buildings comprising a clay material, carbon, and water used to form the cellular ceramic blocks, slabs and beams by expansion of the particles inside the ware. The cellular ceramic materials are produced by first mixing the clay, carbon and about 40% to about 70% water by weight of the clay in the mixture, allowing the mixture to cure, drying the cured mixture, then firing the dried mixture at a temperature and for a period of time sufficient to melt the surface of the mixture. The clay material can be, for example, surface clays, ball clays, kaolin, shale, fly ash and/or bentonite. In another embodiment a mixture of volcanic ash, carbon and water can be formed and layered with the mixture of clay, carbon and water. The cellular ceramic materials are, in most cases, impervious to liquid, are capable of supporting substantial loads in tension and compression without reinforcement, and require no additional insulating material. Such cellular ceramic material may also be used in the construction of buildings with a metal skeleton comprising metal bars forming a structure for supporting the cellular ceramic building material.
US08663541B2	Method of forming a tubular membrane on a structural frame The present invention relates to a medical device and method of forming the medical device. In particular, the present invention relates to a medical device having a tubular membrane structure over a radially expandable structural frame, and to a method of forming the tubular membrane on the radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electro-statically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.
US08663539B1	Process of making a three-dimentional micro-truss structure A three-dimensional micro-truss structure includes: a plurality of first struts extending along a first direction; a plurality of second struts extending along a second direction; a plurality of third struts extending along a third direction; and a plurality of fourth struts extending along a fourth direction, wherein the first, second, third, and fourth struts interpenetrate one another at a plurality of nodes and wherein at least one of the first, second, and third directions extends at a non-perpendicular angle with respect to a plane, the plane being substantially perpendicular to the fourth direction.
US08663537B2	Injection molding apparatus and method A heatsink for use in injection molding, with at least one load-bearing path with a rearward segment, wherein at least a portion of at least one non-load-bearing, dynamic heat-transfer zone of the heatsink is laterally offset from the rearward segment of the load-bearing path.
US08663535B2	Integrated sunshade design A trim panel for a door of a vehicle that wherein both sunshade and non-sunshade versions of the trim panel are manufactured on the same equipment, thus eliminating the need to prepare separate molds for each trim panel. Both the sunshade and non-sunshade versions of the trim panel share essentially the same components and dimension except that the sunshade trim panel has an upper surface that terminates prior to a corresponding surface of the non-sunshade trim panel. This feature allows both trim panels to be made on the same equipment and then installed as needed depending on whether a given door will include a sunshade assembly.
US08663530B2	Water-proof sound-transmitting membrane, method for producing water-proof sound-transmitting membrane, and electrical appliance using the membrane A water-proof sound-transmitting membrane 10 includes a polytetrafluoroethylene porous membrane 1 and has a surface density of 1 to 20 g/m2. The polytetrafluoroethylene porous membrane 1 includes a first porous layer 1a, and a second porous layer 1b stacked on and integrated with the first porous layer 1a by a binding force acting between polytetrafluoroethylene matrices.
US08663529B2	Holder and method for shaping a sound tube The present invention relates to a simplified manufacturing method for provision of a sound tube with a pre-formed shape, especially a sound tube for use in a BTE (Behind-The-Ear) hearing aid utilizing a holder with an external surface for imparting the shape of the surface to the sound tube, a first attachment element that is adapted to receive and hold a first connector at a first end of the sound tube, and a second attachment element that is adapted to receive and hold a second connector at a second end of the sound tube thereby keeping the sound tube in abutting contact with at least parts of the external surface whereby the external surface imparts the shape of the surface to the sound tube.
US08663527B2	Method for arranging engagement means in a concrete part A method for arranging engagement means in a concrete body. These engagement means can come into contact with securing means, resulting in a coupling of considerable strength between the concrete part and the said securing means. The engagement means may comprise a screw thread, bayonet-like structure or the like arranged in the concrete. However, it is also possible for the engagement means to be designed as a separate component which is placed into the concrete material. This separate component is then provided with the engagement means proper in that it is provided with a screw thread, bayonet catch or the like. In this way, it is possible to secure construction parts to the concrete part, to hoist the concrete part and to carry out further actions with this part. It is also possible to adjust the concrete part with the aid of adjustment bolts which engage in the engagement means.
US08663518B2	Methods of producing a titanium dioxide pigment and improving the processability of titanium dioxide pigment particles A method of producing a titanium dioxide pigment is provided. Also provided is a method of improving the processability of titanium dioxide particles without adversely affecting the rheological properties of the titanium dioxide particles.
US08663516B2	Process for manufacturing a block of material that imitates natural stone and the block of material obtained by the implementation thereof A process for manufacturing a block of material that imitates natural stone. The manufactured stone not only looks and appears like natural stone, but is also consistent with the composition of natural stone. The process comprises forming an aqueous mixture of limestone aggregates, treating the mixture with carbon dioxide under pressure and then highly compressing the treated mixture in a sealed mold. This process recreates the endogenous matrix of the natural stone and its original composition. The block of material is intended for construction and decoration purposes.
US08663513B2	Foam earplug extrusion Foam earplugs (90) are produced by extruding foamable material through a nozzle (12) having a throat (30) where the nozzle diameter is smallest, to produce an extrusion (34) that expands in diameter along an expansion zone (D) as the extrusion moves forward. Applicant moves dies (70, 72) against opposite sides of the extrusion and then moves the dies forward with the moving extrusion while the foam solidifies into earplugs. The earplugs to be formed have sealing portions that seal to a person's ear canal, of a maximum diameter G of about 0.4 inch, and the nozzle throat has a diameter B no more than 0.1 inch to provide a long expansion zone so the dies can begin to mold the extrusion while the extrusion is still expanding in diameter.
US08663511B2	Encapsulated materials and methods for encapsulating materials A system that incorporates teachings of the present disclosure may include, for example, a method for applying a force to at least one of an inner stream, an outer stream or both of a combined stream to produce a plurality of capsules, receiving image data, processing the image data, detecting undesirable capsules from the processed image data, applying a bias charge only to the detected undesirable capsules, and segregating the biased undesirable capsules from the unbiased desirable capsules. Additional embodiments are disclosed.
US08663506B2	Process for uniform and higher loading of metallic fillers into a polymer matrix using a highly porous host material A method relating to making a metal coated filler includes mixing a solution of an organic diol with a plurality of porous filler particles to obtain a support mixture; contacting a metal salt solution with the support mixture forming a reaction mixture; and heating the reaction mixture to a temperature within a temperature range from about 50 degrees Celsius to about 200 degrees Celsius. The metal cations in the metal salt solution are reduced to metal particles by the organic diol and are disposed on the porous filler particles and on filler particle pore surfaces. The metal coated filler may then be optionally isolated. Electrically and/or thermally conductive articles including the metal coated fillers and methods for their manufacture are also disclosed.
US08663505B2	Process for producing conducting polymers The present invention relates to novel processes for preparing an aqueous or nonaqueous dispersion or solution comprising at least one conductive polymer and at least one polyanion, characterized in that the polymerization is performed at a pressure below atmospheric pressure, to aqueous or nonaqueous dispersions or solutions prepared by this process and to the use thereof.
US08663500B2	α-sialon phosphor, method for producing same, and light-emitting device α-sialon phosphor that is α-sialon represented by a general expression: (M)x(Eu)y(Si, Al)12(O, N)16 (where M is one or more types of elements selected from a group consisting of Li, Mg, Ca, and Y as well as lanthanide element (except for La and Ce) and including at least Ca), the α-sialon phosphor being structured so that an oxygen content is 1.2 mass % or less and primary particles constituting the α-sialon have a columnar shape. When the α-sialon phosphor receives ultraviolet rays or visible light having a wavelength from 250 to 500 nm as an excitation source, the α-sialon phosphor shows a fluorescent characteristic having a peak in a wavelength region from 595 to 630 nm.
US08663499B2	Luminophores and core-shell luminophore precursors A novel type of green luminophore containing mixed rare-earth phosphates is produced from precursor particles having a mean diameter ranging from 1.5 to 15 microns; such particles have an inorganic core and a shell of a mixed lanthanum and/or cerium phosphate, optionally doped with terbium, evenly covering the inorganic core with a thickness greater than or equal to 300 nm.
US08663494B2	Terpene, terpenoid, and fullerene stabilizers for fluoroolefins The present invention relates to compositions comprising at least one fluoroolefin and an effective amount of stabilizer that may be a terpene, terpenoid or fullerene; or a mixture of a terpene, terpenoid or fullerene with other stabilizers. The stabilized compositions may be useful in cooling apparatus, such as refrigeration, air-conditioning, chillers, and heat pumps, as well as in applications as foam blowing agents, solvents, aerosol propellants, fire extinguishants, and sterilants.
US08663490B2	Semiconductor wafer handler A semiconductor wafer handler comprises a ring (70) attached to a hub (80) by a plurality of spokes (90). Vacuum is applied to the surface of the semiconductor wafer through orifices (100) containing in the ring (70). Water and/or nitrogen can be applied to the surface of the semiconductor wafer through orifices (110) contained in the spokes (90).
US08663486B2	Method of manufacturing a magnetic recording medium A method of manufacturing a magnetic recording medium, includes, in the order recited, the steps of forming a mask protective film composed of carbon on a magnetic layer; forming a resist with a predetermined pattern on the mask protective film; forming a protective mask by etching the mask protective film using the resist as a mask; forming protrusions and recesses on a magnetic layer by etching the magnetic layer using the resist and the protective mask as masks; removing the protective mask, including removing the mask protective film comprised of carbon, using ultraviolet light with a principal wavelength not longer than 340 nm; and forming a protective layer on the magnetic layer having the protrusions and recesses formed thereon.
US08663484B2	Method for manufacturing a printed circuit board and a printed circuit board obtained by the manufacturing method A method for manufacturing a printed circuit board enables a metal residue between wirings to be removed inexpensively without side etching of a copper layer while having sufficient insulation reliability for micro wiring working. The method includes forming a base metal layer directly at least on one face of an insulator film without an adhesive, and a copper coat layer formed on the base metal layer to form adhesiveless copper clad laminates, then forming a pattern on the adhesiveless copper clad laminates by an etching method. The etching method includes a process of etching treatment for the adhesiveless copper clad laminates with an iron (III) chloride solution or a copper (II) chloride solution containing hydrochloric acid and then, a process of treatment with an acid oxidant containing potassium permanganate.
US08663483B2	Radial vane pack for rotary separators Apparatus and methods for separating a fluid, with the apparatus including an inner drum wall disposed around and coupled to a shaft. The apparatus also includes an outer drum wall disposed around the inner drum wall, the outer drum wall being configured to rotate to separate a higher-density component of the fluid from a lower-density component of the fluid. The apparatus further includes a first radial vane disposed between the inner drum wall and the outer drum wall and having first contours configured to turn the fluid in at least one of a radially-inward direction and a radially-outward direction. The apparatus also includes a housing at least partially surrounding the outer drum wall and configured to receive the high-density component of the fluid therefrom.
US08663473B2	Digestion of biosolids in wastewater A method enhancing biological digestion of wastewater sludge is provided. The method uses chlorine dioxide to accelerate and improve the efficiency of aerobic or anaerobic digestion.
US08663471B1	Apparatus and method for treating aqueous solutions and contaminants therein The present disclosure is generally directed to devices and methods of treating aqueous solutions to help remove or otherwise reduce levels, concentrations or amounts of one or more contaminants. The present disclosure relates to a apparatus including a substantially self-contained housing or container which is adapted to receive components including at least one counterelectrode (e.g. cathode) and at least one photoelectrode (e.g. anode) provided or arranged around at least one UV light source, and/or receive, contain and/or circulate fluid or aqueous solution.
US08663469B2	Strainer wall structure including curved sections A strainer wall structure includes curved sections, a method of manufacturing the same, and a filtering method using the strainer wall structure to provide a substantially larger effective filtering area in the same length and width, substantially reducing foreign substances covering a suction surface and flow resistance of the foreign substances, and reducing pressure drop at a cooling water pass corresponding thereto. The strainer wall structure includes an inlet side through which cooling water is introduced and an outlet side through which the filtered cooling water is discharged, includes a body having openings in directions of the inlet side and the outlet side, and a first filter plate inserted into the body and including curved sections formed by alternately bending a first punched plate having filtering holes in opposite directions and at a predetermined interval.
US08663468B2	Reactor for anaerobic purification of waste water including multi-phase separator devices A reactor for anaerobically purifying waste water, such as waste water from the paper industry, includes a reactor vessel that has at least one inlet for supplying waste water to be purified into the reactor, at least one outlet for discharging purified water, at least one sediment filter and at least two multi-phase separator devices arranged on top of one another.
US08663461B2	Extraction process with novel solvent regeneration methods Solvent regeneration to recover a polar hydrocarbon (HC) selective solvent substantially free of hydrocarbons (HCs) and other impurities from a solvent-rich stream containing selective solvent, heavy HCs, and polymeric materials (PMs) generated from reactions among thermally decomposed or oxidized solvent, heavy HCs, and additives is provided. A combination of displacement agent and associated co-displacement agent squeezes out the heavy HCs and PMs from the extractive solvent within a solvent clean-up zone. Simultaneously, a filter equipped with a magnetic field is positioned in a lean solvent circulation line to remove paramagnetic contaminants. The presence of the co-displacement agent significantly enhances the capability of the displacement agent in removing the heavy HCs and PMs from the extractive solvent. As a result, the solvent regeneration system operates under milder conditions and minimizes or eliminates the need for including a high temperature, energy intensive and difficult-to-operate thermal solvent regenerator.
US08663460B2	Process, method, and system for removing heavy metals from fluids Trace element levels of heavy metals such as mercury in crude oil are reduced by contacting the crude oil with an iodine source, generating a water soluble heavy metal complex for subsequent removal from the crude oil. In one embodiment, the iodine source is generated in-situ in an oxidation-reduction reaction, by adding the crude oil to an iodine species having a charge and a reductant or an oxidant depending on the charge of the iodine species. In one embodiment with an iodine species having a positive charge and a reducing reagent, a complexing agent is also added to the crude oil to extract the heavy metal complex into the water phase to form water soluble heavy metal complexes which can be separated from the crude oil, for a treated crude oil having reduced levels of heavy metals.
US08663457B2	Methods and compounds for improving sulfide scavenging activity Methods for reducing sulfides from fluid streams are provided. The methods comprise adding secondary amine-formaldehyde adduct (SAFA) scavengers to fluid streams. The SAFA scavengers added comprise less than about 40 wt % N-methyl secondary amines of the total weight of SAFA scavengers. Methods for distilling N-methyl secondary amines from secondary amine-formaldehyde adduct (SAFA) scavengers are also provided. Purified SAFA scavengers are also disclosed.
US08663452B2	Electrolytic cells and methods for the production of ammonia and hydrogen A method using an electrolytic cell to electrolyze urea to produce at least one of H2 and NH3 is described. An electrolytic cell having a cathode with a first conducting component, an anode with a second conducting component, urea and an alkaline electrolyte composition in electrical communication with the anode and the cathode is used to electrolyze urea. The alkaline electrolyte composition has a hydroxide concentration of at least 0.01 M.
US08663451B2	Linker, impedance biochip, and method of quantitatively detecting target analyte in fluid sample using the biochip The present invention provides a linker for joining an electrode and a capture probe on a biochip, and a biochip comprising the linker. The impedance baseline of the linker of the present invention is three orders lower than the conventional long chain thiol linker when adopting in a fadaraic impedance biochip construction. With lower impedance baseline, the device designed to measure the signal of the biochip of the present invention could be further simplied on the electrical circuit design and be made in lower cost, compacter size and get the potential to be used in point-of-care applications. The present invention also provides a method of quantitatively detecting a concentration of a target analyte in a fluid sample by adopting the biochip and the linker of present invention.
US08663450B1	Guide bore electrical machining methods A method of electrically machining a hole in a conductive work piece may include providing a tool having a conductive tool head in close proximity to the conductive work piece. A voltage may be applied across the tool head and the work piece to create an electric field in the hole at the tool head. The electric field may be asymmetric with respect to the centerline of the hole. The orientation of the hole may be altered by removing material from the work piece using the asymmetric electric field.
US08663449B2	Feed control method for wire cutting electrochemical discharge machining and apparatus thereof A feed control method for wire cutting electrochemical discharge machining is disclosed. The method determines whether a contact event has occurred using a wire electrode, based on variations in wire tension when being cut. A wire is cut with an ideal feed speed when the wire electrode is not in contact with a workpiece.
US08663439B2	Sputtering target for producing metallic glass membrane and manufacturing method thereof A sputtering target for producing a metallic glass membrane characterized in comprising a structure obtained by sintering atomized powder having a composition of a ternary compound system or greater with at least one or more metal elements selected from Pd, Zr, Fe, Co, Cu and Ni as its main component (component of greatest atomic %), and being an average grain size of 50 μm or less. The prepared metallic glass membrane can be used as a substitute for conventional high-cost bulk metallic glass obtained by quenching of molten metal. This sputtering target for producing the metallic glass membrane is also free from problems such as defects in the metallic glass membrane and unevenness of composition, has a uniform structure, can be produced efficiently and at low cost, and does not generate many nodules or particles. Further provided is a method for manufacturing such a sputtering target for forming the metallic glass membrane.
US08663438B2	Target arrangement The invention relates to a target arrangement comprising a tubular-shaped carrier element and a hollow-cylindrical target having at least one target material, said target comprising at least one one-piece tube segment which at least partially surrounds the carrier element. Said carrier element and the tube segment are partially interconnected in a material fit by at least two plastically deformable compensating means. The invention also relates to a method for producing said type of target arrangement and a tubular segment.
US08663436B2	Water electrolysis system A water electrolysis system includes a high-pressure water electrolysis apparatus and a gas-liquid separation device. The gas-liquid separation device includes a block member which includes a gas-liquid separation opening and a water-level detection opening. The gas-liquid separation opening and the water-level detection opening extend substantially vertically and includes respective bottom portions which integrally communicate with a discharge pipe. The discharge pipe is disposed at a lower side portion of the block member. The water-level detection opening includes a top portion and a top water-level detection section. The block member further includes an inlet hole in which the hydrogen is introduced from the high-pressure water electrolysis device. The inlet hole is disposed at an upper side portion of the block member. The inlet hole is positioned above the top water-level detection section of the water-level detection opening.
US08663421B2	Apparatus and method of manufacturing absorbent article An apparatus that manufactures an absorbent article includes a rotating member that rotates in a state where the rotating member is opposing one face of a continuous sheet that is moving, the rotating member having an arcuate retaining surface that retains a work, the rotating member causing the work to be moved to a position where the work is nipped between the one face and the arcuate retaining surface by rotating in a state where the work is retained on the arcuate retaining surface; and a pressing member that bonds a continuous sheet and a work together by coming into contact with another face of the continuous sheet when the work reaches the position and pressing the continuous sheet towards the arcuate retaining surface.
US08663419B2	Manual container assembly and liner integration fixture for pulp-molded shell with polymer liner container systems A method of using a assembly facilitator for a pulp-molded shell with polymer liner containing systems to precisely create a integral pulp molded shell is disclosed along with the assembly facilitator itself.
US08663418B2	Method of forming a roofing product including a ceramic base material and recycled roofing material A method of forming a roofing product can include providing a ceramic base material having an open structure, and filling the open structure of the ceramic base material with a bituminous material. In a particular embodiment, the bituminous material has no greater than approximately 5 weight % of abrasive particles or has a first particle size distribution. The method can further include applying a recycled roofing material. In an embodiment, the recycled roofing material is applied along a principal surface of the ceramic base material or adjacent to the ceramic base material. In a particular embodiment, the recycled roofing material has at least 2 weight % acid-insoluble solids or has a second particle size distribution that is narrower than the first particle size distribution.
US08663414B2	Polyurethane-based pultrusion resin system The present invention relates to a pultrusion resin system, comprising (a) di- or polyisocyanates, (b) compounds having at least two groups reactive toward isocyanates, (c) catalyst, (d) polybasic acid with functionality greater than or equal to 2 and, optionally, (e) further auxiliaries and additives, where the boiling point of the polybasic acid is at least 200° C. at standard pressure and it is soluble in the compound having at least two groups reactive toward isocyanates. The invention further relates to a process for producing a pultrudate, and also to this pultrudate.
US08663413B1	White and black ply laminate and methods According to one embodiment, a method of making a roofing membrane is provided. According to the method, an ethylene propylene diene monomer rubber (EPDM) material sheet is provided and a thermoplastic polyolefin (TPO) material sheet is extruded onto the EPDM material sheet. The EPDM material sheet and TPO material sheet are then pressed together via one or more rollers. The EPDM material is uncured and has a thickness of between about 50 mils and 70 mils. The extruded TPO sheet has a temperature of at least 150 degrees Celsius and a thickness of between about 15 mils and 35 mils. The heat of the TPO material sheet causes a top portion of the EPDM material sheet to cure such that crosslinking of the TPO and EPDM material sheets occurs at an interface of the sheets to bond the sheets together.
US08663410B2	System for finishing printed labels using multiple X-Y cutters A label finishing station receives a web carrying printed images for labels arranged so there are a plurality of images formed in rows or ranks across the width of the web. The images are also arranged in longitudinal columns along the length of the web. A cutting station carries a plurality of cutter heads to cut out the plurality of labels forming each row or rank simultaneously. The web, with the label peripheries cut out, may be slit longitudinally and formed into finished rolls of labels.
US08663409B2	Touch fastening Touch fastener products (10) are made by distributing a multiplicity of discrete fastening bits (14, 14a, 14b) over a support surface (12) and fixing the distributed bits (14, 14a, 14b) to the support surface (12), such as by an adhesive (32). Each bit (14, 14a, 14b) has opposite side surfaces (24, 24b, 26, 26b) forming boundaries of surfaces defining projections (16) extending in different directions from the fastening bits (14, 14a, 14b), at least one of the opposite side surfaces (24, 24b, 26, 26b) being non-planar, and each projection (16) has an overhanging head (18). As fixed, each bit (14, 14a, 14b) is oriented with at least one of its projection heads (18) raised from the support surface (12) to releasably engage fibers (30). Bits (14, 14a, 14b) are made by pelletizing shaped rails (36). Applications include securing floor coverings (150).
US08663406B1	Melt cast insensitive eutectic explosive A insensitive explosive comprises: 34.9 wt % diethylenetriamine trinitrate (DETN), 33.4 wt % ethylenediamine dinitrate (EDD), 25.4 wt % methyl-guanidine (MeNQ), and 6.3 wt % guanidine (NQ). This quaternary eutectic is used in combination with a sensitive explosive. A low melting temperature facilitates melt casting to fill 155 mm artillery shells.
US08663401B2	Degradable compositions, apparatus comprising same, and methods of use Compositions, apparatus incorporating a composition, and methods of use are described, one composition embodiment consisting essentially of one or more reactive metals in major proportion, and one or more alloying elements in minor proportion, with the provisos that the composition is high-strength, controllably reactive, and degradable under defined conditions. Compositions of the invention may exist in a variety of morphologies, including a reactive metal or degradable alloy processed into an alloy of crystalline, amorphous or mixed structure that may constitute the matrix of other composition, for instance a composite. Methods of using apparatus comprising a composition, particularly in oilfield operations are also described (e.g. flow and displacement control, sensors, actuators). This abstract allows a searcher or other reader to quickly ascertain the subject matter of the disclosure. It will not be used to interpret or limit the scope or meaning of the claims.
US08663399B2	Iron-based high saturation induction amorphous alloy An iron-based amorphous alloy and magnetic core with an iron-based amorphous alloy having a chemical composition with a formula FeaBbSicCd, where 81
US08663396B2	Method for cleaning oil soaked bonded panels and laminates A method of cleaning a contaminated composite part, so as to provide a surface suitable for adhesive bonding. The method includes applying a wicking medium adjacent to a surface of the contaminated composite material. Then applying a solvent medium soaked in a cleaning solution adjacent to the wicking medium. Then vapor barrier is applied adjacent to the solvent medium. Next a breather material is applied adjacent to the vapor barrier. Then a vacuum bagging film with a vacuum port is applied and sealed against the composite part. The composite part is then heated and vented to remove contaminates from the composite material.
US08663395B2	Warewasher including heat recovery system with hot water supplement A warewasher for washing wares includes a housing defining an internal space with at least one spray zone for washing wares. A liquid delivery system provides a spray of liquid within the spray zone. A tank includes an inlet that is connected to a hot water source for filling the tank with hot water. The liquid delivery system receives water from the tank. An exhaust vents heated air from the housing. A final rinse system is connected to a cold water source. A heat recovery system is located between the final rinse system and the cold water source. The heat recovery system transfers heat from the exhaust air to the cold water provided from the cold water source. A valve associated with the hot water source selectively supplements the water exiting the heat recovery system with hot water from the hot water source.
US08663394B2	Dishwasher including additive feeder used in conjunction with setting a pressure for washing dishes, and method thereof A dishwasher, in particular a domestic dishwasher, having a dishwashing compartment and apparatuses for washing tableware using washing liquor, wherein it is possible to set the pressure in the apparatuses for washing tableware. A feed apparatus for an additive is provided, and the pressure in the apparatuses for washing tableware can be set as a function of the metering of the additive in the feed apparatus.
US08663391B2	Electrostatic chuck having a plurality of heater coils An electrostatic chuck for receiving a substrate in a substrate processing chamber comprises a ceramic puck having a substrate receiving surface having a plurality of spaced apart mesas, an opposing backside surface, and central and peripheral portions. A plurality of heat transfer gas conduits traverse the ceramic puck and terminate in ports on the substrate receiving surface to provide heat transfer gas to the substrate receiving surface. An electrode is embedded in the ceramic puck to generate an electrostatic force to retain a substrate placed on the substrate receiving surface. A plurality of heater coils are also embedded in the ceramic puck, the heaters being radially spaced apart and concentric to one another.
US08663390B2	Independent radiant gas preheating for precursor disassociation control and gas reaction kinetics in low temperature CVD systems A method and apparatus for delivering precursor materials to a processing chamber is provided. In one embodiment, a deposition apparatus is provided. The apparatus includes a chamber having a longitudinal axis, and a gas distribution assembly coupled to a sidewall of the chamber. The gas distribution assembly comprises a plurality of plenums coupled to one or more gas sources, an energy source positioned to provide energy to each of the plurality of plenums, and a variable power source coupled to the energy source, wherein the gas distribution assembly provides a flow path through the chamber that is normal to the longitudinal axis of the chamber.
US08663388B2	Method of manufacturing single crystal wire and other single crystal metallic articles Disclosed are a single crystal wire and other single crystal articles, and a manufacturing method thereof. The method comprises the steps of: placing into a growth crucible at least one metal selected from the group consisting of gold, copper, silver, aluminum and nickel; heating and melting the metal placed in the growth crucible; growing a single crystal using metal crystal as a seed by Czochralski or Bridgman method; cutting the grown single crystal by electric discharge machining; and machining the cut single crystal and producing a wire or other articles such as a ring. In the method, the grown metal single crystal is cut into a disc-shaped piece by electric discharge machining. The piece is transformed into a single crystal wire or other articles by wire-cut electric discharge machining, and the single crystal wire can be used as a ring, a pendant, or a wire for high-quality cables for audio and video systems. Also, the single crystal formed into the disc-shaped piece by electric discharge machining can be used as a substrate and a target for deposition.
US08663386B2	Dry cement mix for forming light concretes with low thermal conductivity, and concretes thus obtained A dry cement mix based on a hydraulic binder and a glass aggregate for forming light concretes with low thermal conductivity, characterized in that said glass aggregate comprises a fine fraction consisting of granulated aggregate with a particle size from 0.5 to 2 mm, and a coarse fraction consisting of crushed aggregate with a particle size from 4 to 20 mm, obtaining for said glass aggregate a well-defined overall particle size distribution.
US08663385B2	Montan wax substitute for gypsum products A method of manufacturing a water-resistant gypsum product including forming an aqueous mixture of gypsum, water and a wax mixture, wherein the wax mixture includes a hydrocarbon wax, and a substitute material selected from the group consisting of (a) an asphaltite, (b) a polyolefin homopolymer, (c) a polyolefin copolymer, and (d) combinations thereof; and forming the mixture into a structure, and drying the structure while permitting hydration of the gypsum to form a gypsum product.
US08663383B2	Expansive material and its preparation process The invention provides an expansive material that allows for large expansion of concrete at a material age of 2 to 7 days after pouring and permits concrete to have higher initial compressive strength and makes sure good storage stability, and a process for preparing that expansive material.The invention provides an expansive material and a process for preparing that expansive material, characterized in that clinker or pulverized clinker containing free lime, a hydraulic compound and calcium sulfate anhydrite is heat treated in a carbon dioxide gas atmosphere to form calcium carbonate in it. Preferably, the expansive material contains a particle in which the free lime, hydraulic compound, calcium sulfate anhydrite and calcium carbonate are all present; the content of calcium carbonate is 0.5 to 10% by mass; and the expansive material has a Blaine's specific surface area of 1,500 to 90,000 cm2/g. The expansive material is blended with cement into a cement composition. The preparation conditions are preferably a carbon dioxide gas flow rate of 0.01 to 0.1 L/min. and a temperature of 200 to 800° C., under which conditions there is calcium carbonate formed.
US08663382B2	High strength phosphate-based cement having low alkalinity A mixture for making a high strength phosphate cement includes monopotassium phosphate, a Group IIA metal oxide in amounts of about 20 to about 100 parts per 100 parts of the monopotassium phosphate and monocalcium orthophosphate in amounts of from about 3 to about 30 parts per 100 parts of the monopotassium phosphate. Products made from the phosphate cement have a pH of less than about 9 and the product develops a compressive strength greater than 2000 psi in 24 hours.
US08663378B2	Asphalt mix workable at ambient temperatures with only biodegradable solvents and method of manufacturing the same A method of manufacturing an asphalt mix comprising: heating aggregate; introducing RAP to the aggregate; dry mixing the RAP and aggregate; forming a coating of AC on all aggregate during the step of dry mixing by extending the length in time of the dry mixing step; separately blending AC, biodegradable solvents, and anti-stripping agent to produce a blend; and wet mixing the blend into the RAP and aggregate mix. The biodegradable solvents are capable of making the asphalt mix workable at ambient temperatures and comprise pine extract and biodiesel. The length of the dry mixing is extended to at least about 35 seconds. The aggregate comprises coarse and fine virgin aggregate. RAP is about 40% of the final product. The asphalt mix is stockpiled and bagged. The method further comprises manipulating encrusted material on the outside of the stockpiled cold asphalt mix back into the stockpile.
US08663374B2	Electrostatic aerosol concentrator An apparatus for concentrating aerosol particles can include: a sample air inlet; an enriched aerosol outlet; an aerosol lean outlet; a flow path connecting the air inlet and aerosol rich and aerosol lean outlets; and a plurality of alternately energized and grounded electrode pairs along the flow path. The aerosol rich outlet can be in fluid communication with an aerosol particle capture device. The apparatus can include a sheath air inlet providing a flow of aerosol free air over surfaces of the alternately energized and grounded electrode pairs. The apparatus can include an elongate focusing chamber having a cylindrical shape containing the alternately energized and grounded electrode pairs that are configured as circular rings. The apparatus can include one or more structures configured to impart tangential, spiral or helical flow to a stream entering through the sample air inlet.
US08663370B2	Breather for crankcase ventilation system An engine crankcase breather for oil segregation, from blow-by gases, in an engine. The engine crankcase breather includes a housing with an inlet located in a downstream direction of the blow-by gases and an outlet. The breather also includes a baffle within the housing which poses a tortuous path for the blow-by gases, in order to segregate oil particles from the blow-by gases. The baffle includes a hook-shaped portion, in which the oil segregation takes place. The engine crankcase breather further includes a trough extending within the housing. The trough is aligned with the hook-shaped portion of the baffle, to collect the segregated oil from the blow-by gases.
US08663369B2	Separation of gases produced by combustion The present invention is directed to a method and a system for separating gas components of a combustion gas. A compressible feed stream derived from a combustion gas that contains at least one target compressible component and at least one non-target compressible component is mixed in a substantially co-current flow with an incompressible fluid stream comprising an incompressible fluid in which the target component(s) is/are capable of being preferentially absorbed. Rotational velocity is imparted to the mixed streams, separating an incompressible fluid in which at least a portion of the target component is absorbed from a compressible product stream containing the non-target compressible component(s). The compressible feed stream may be provided at a stream velocity having a Mach number of at least 0.1.
US08663366B2	Device and method for removing humidity/moisture from a closed container or area The invention is directed to a device that removes humidity/moisture from a container or enclosed area. The device includes a plastic housing having a cavity chamber. A silica desiccant is in the cavity chamber. A color indicator indicates if the silica desiccant is active. A polyester screen/filter is heat welded to the raised circles on the bottom inside of the cavity chamber of the plastic housing. The polyester screen/filter ensures that the silica desiccant stays inside the housing even when the device is reactivated in a microwave or oven. A cover with a number of holes may be placed over the screen/filter and the screen/filter may be welded to the cover. The cover and housing may be made out of food safe polypropylene.
US08663361B1	Methods of recovering alkali metals Approaches for alkali metal extraction, sequestration and recovery are described. For example, a method of recovering alkali metals includes providing a CST or CST-like (e.g., small pore zeolite) material. The alkali metal species is scavenged from the liquid mixture by the CST or CST-like material. The alkali metal species is extracted from the CST or CST-like material.
US08663356B2	Honeycomb structure A honeycomb structure wherein the thickness of each partition wall is 50.8 μm inclusive to 161.5 μm exclusive, the cell density is 15.5 to 62.0 cells/cm2, the cell opening ratio of the honeycomb structure body is 76 to 91%, the porosity of the partition walls is 35 to 45%, the average pore diameter of the partition walls is 2 μm inclusive to 10 μm exclusive, the material for the partition walls includes at least one member selected from the group consisting of cordierite, aluminum titanate, silicon carbide, alumina and mullite, and the value obtained by dividing the average pore diameter of the partition walls by the thickness of the partition walls is larger than 0.04 but smaller than 0.065.
US08663355B2	Air filter arrangement; assembly; and, methods Air cleaner assemblies and components therefor are described. An example first or main filter cartridge is described which includes a media pack comprising strips of fluted material secured to facing sheets, oriented in a stack. The media pack defines opposite inlet and outlet flow faces, with flutes extending in a direction therebetween. The media pack is non-removably secured within a filter cartridge housing, at a location between opposite sections of a shell, typically secured thereto with an adhesive. The shell also defines a closed end, spaced from, but in overlap with, the outlet end face of the media pack. The closed end is typically curved and the shell typically provides either a d/b-shape or a u-shape.
US08663349B2	Polycrystalline diamond compacts, and related methods and applications Embodiments of the invention relate to polycrystalline diamond compacts (“PDCs”) and methods of fabricating polycrystalline diamond tables and PDCs in a manner that facilitates removal of metal-solvent catalyst used in the manufacture of polycrystalline diamond tables of such PDCs.
US08663347B2	Fire log A fire log is provided which is comprised of a mixture of ground mature sweet corn kernels and water. A second embodiment is disclosed wherein the fire log is comprised of ground mature sweet corn kernels, chopped or ground corn cobs and water. A third embodiment is disclosed wherein the fire log is comprised of ground mature sweet corn kernels, chopped or ground sweet corn cobs and chopped or ground sweet corn stalks mixed with water. A fourth embodiment of the fire log is disclosed wherein the fire log is comprised of ground mature sweet corn kernels, water and conventional combustible petroleum materials such as used in conventional fire logs. The mixture is pressed, formed or extruded to form cylindrical fire logs or block fire logs.
US08663345B2	Production of biodiesel and glycerin from high free fatty acid feedstocks A system and method for the conversion of free fatty acids to glycerides and the subsequent conversion of glycerides to glycerin and biodiesel includes the transesterification of a glyceride stream with an alcohol. The fatty acid alkyl esters are separated from the glycerin to produce a first liquid phase containing a fatty acid alkyl ester rich (concentrated) stream and a second liquid phase containing a glycerin rich (concentrated) stream. The fatty acid alkyl ester rich stream is then subjected to distillation, preferably reactive distillation, wherein the stream undergoes both physical separation and chemical reaction. The fatty acid alkyl ester rich stream is then purified to produce a purified biodiesel product and a glyceride rich residue stream. Neutralization of the alkaline stream, formed during the alkali-catalyzed transesterfication process, may proceed by the addition of a mineral or an organic acid.
US08663342B2	Process for producing nitrogen-containing composition The invention provides a process comprising: a crystallization step of concentrating and crystallizing the ammonium salt of sulfuric acid from an aqueous solution that contains the ammonium salt of sulfuric acid; a solid-liquid separation step of solid-liquid separating the ammonium salt of sulfuric acid obtained in the crystallization step, and a crystallization mother liquid recycling step of recycling a crystallization mother liquid obtained in the solid-liquid separation step to at least one step selected from the crystallization step and one or more steps that precede the crystallization step, in which not all of the crystallization mother liquid is recycled.
US08663341B2	Hair colorant compositions comprising 2-Methoxymethy1-1,4-diaminobenzene, methods, and kits comprising the compositions A hair colorant composition comprises 2-methoxymethyl-1,4-diaminobenzene developer in combination with other p-phenylenediamine developers and selected couplers. A kit for coloring hair comprises the hair colorant composition. A method of treating hair comprises applying the hair colorant composition to hair.
US08663339B2	Adjusting device and method for operating an adjusting device The invention relates to an adjusting device for a prosthetic device, having a drive (1) for adjusting at least one first component of the prosthetic device relative to a second component, wherein the drive (1) is designed as a permanent magnet electric motor and comprises a stator (4) having exciter coils (3) and a rotor (2) having at least one permanent magnet is an armature magnet (5). At least one holding magnet (6) in the form of a permanent magnet is arranged on the stator (4) to form a cogging torque for the rotor (2).
US08663338B2	Pyloric valve obstructing devices and methods Methods, devices and systems facilitate intermittent and/or partial obstruction of a pyloric valve. Devices generally include a support portion for preventing the device from passing through the pyloric valve and a tissue engagement portion for contacting tissue adjacent the pyloric valve to obstruct the valve. Some embodiments also include a positioning member extending from the tissue engagement portion for helping position the device for obstructing the valve. A retaining member may optionally be included on the distal end of the positioning member for further maintaining a position of the device in the stomach. Some embodiments are deliverable into the stomach through the esophagus, either by swallowing or through a delivery tube or catheter. Some embodiments are fully reversible. Some embodiments self-expand within the stomach, while others are inflated or otherwise expanded.
US08663332B1	Bone graft distribution system A system for distributing bone graft material in an intervertebral disc space is provided having a central beam having a proximal portion having an end, a grafting portion having a top and a bottom, a distal portion having a end, a central beam axis, a graft distribution channel having an entry port at the end of the proximal portion, a top exit port at the top of the grafting portion, and a bottom exit port at the bottom of the grafting portion. These systems can also include a laterovertically-expanding frame operable for a reversible collapse from an expanded state into a collapsed state. The expanded state, for example, can be configured to have an open graft distribution window that at least substantially closes upon the reversible collapse.
US08663327B2	Modular junction seal of an orthopedic implant A seal for preventing a bodily fluid from penetrating an orthopedic implant comprising a tapered section adapted to conformingly mate to a stem of a first implant component, and a collar section extending from and circumferentially surrounding a portion of the tapered section, the collar section adapted to mate to a base of a second implant component such that the tapered section and collar section define an opening therethrough configured to receive the first implant component.
US08663321B2	Minimally invasive method for coronary bypass and other treatments Treatment methods and devices are provided for percutaneously accessing a patient's thoracic region via a controlled opening in the aorta, so that cardiac procedures, such as a coronary bypass procedure, can be performed in a minimally invasive manner. Advantageously, it may be possible to perform the procedure without placing the patient on cardiopulmonary bypass. The method may include percutaneously delivering at least one catheter into an aorta of a heart, forming a controlled opening in the aorta and pericardium via the at least one catheter to access a thoracic region within the patient's chest, and performing at least one coronary bypass graft procedure through the controlled opening.
US08663319B2	Methods and apparatus for percutaneous aortic valve replacement A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve including a reversibly expandable occluding means surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The stent(s) displace the native tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the stent(s) at the aortic annulus with precision and relative ease.
US08663315B2	Stent for protecting bifurcated blood vessels in bifurcation lesion The present invention relates to a stent for protecting a branch blood vessel at a branch-point lesion. The stent is inserted into and widened in a main blood vessel having the branch blood vessel extending in a slant from the branch-point lesion, thereby simultaneously expanding the main blood vessel and providing a smooth flow of blood towards the branch blood vessel. As a result, it is possible to simultaneously expand the main blood vessel and to sufficiently secure a passage from the main blood vessel towards the branch blood vessel. As such, the flow of blood is kept smooth. Further, after the stent is inserted into the main blood vessel, another stent, a guide wire, and related tools and catheter can be inserted in the direction of the branch blood vessel in a more accurate manner.
US08663311B2	Device comprising biodegradable bistable or multistable cells and methods of use Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable configuration having a smaller diameter than the expanded configuration.
US08663310B2	Hybrid type A dissection device A hybrid stent graft device for treatment of a Type A dissection having a first tubular portion for placement into the ascending aorta and a second tubular portion for extending around the thoracic arch and down the descending aorta is disclosed. The first tubular portion is connectable to the aorta between the sinotubular junction and the brachiocephalic artery so that it essentially replaces the ascending aorta. A temporary bypass tube allows perfusion during an operation. The second tubular portion has an elongate recess outside of the second tubular portion and an aperture defining a fluid flow path into the recess. The recess is intended to engage an outer curve of the thoracic arch to enable blood flow into the arteries of the thoracic arch. An introduction device in combination with the hybrid stent graft described above is also disclosed.
US08663308B2	Graft with bioabsorbable support frame The medical devices, such as stent grafts, described herein preferably include a tubular remodelable graft material attached to a support frame formed at least in part from a metallic bioabsorbable material. The remodelable graft material preferably includes an extracellular matrix material such as small intestinal submucosa (SIS). The support frame attached to the graft is preferably a bioabsorbable magnesium alloy. The devices may be implanted within a peripheral vascular body vessel from a percutaneous delivery catheter.
US08663307B2	Endoluminal prosthesis An endoluminal prosthesis is provided that includes a tubular graft and an expandable annular support structure for use in a body lumen through which body fluids flow. The annular support structure is coupled to the tubular graft where it is to be sealingly engaged with the inner wall of a body lumen so that the graft and support structure, in combination, provide an improved seal. An embodiment according to the invention provides an annular structure with longitudinally staggered apices providing multiple levels of contact with the inner body lumen wall to provide a seal at multiple levels along the length of the prosthesis. One embodiment relates to tubular grafts for endoluminal placement within blood vessels for the treatment of abdominal and other aneurysms.
US08663306B2	Introducer with extension A stent graft delivery device (1) has an elongated extension piece (20) extending from its proximal end of the introducer portion (3). The elongate extension piece is selectively separable from the introducer portion. A plurality of auxiliary guide wires (50) extend from through the stent graft delivery device and through the elongate extension piece. The auxiliary guide wires can cross over at the proximal end of the extension piece and return. The stent graft delivery device can be introduced into a patient via a femoral artery and the elongated extension piece can extend out an artery of the thoracic arch whereby to extend the auxiliary guide wires out of such an artery to give through and through guide wires. Catheterization of pararenal arteries is then possible via a brachial route.
US08663296B2	Bone anchored surgical mesh A bone-anchored surgical mesh has slot-like anchoring members that allow for the variable placement of screws and other bone fasteners. This permits the surgeon discretion in the placement of bone fasteners used to attach the mesh to the patient's bone. The elongate openings of the anchoring members allow for a sliding motion between the bone fasteners and the anchoring members, and facilitates positioning and articulation of the mesh. The anchoring members may include bushings to aid the sliding motion of the anchoring member on the bone fastener. In one embodiment, the mesh consists of shorter modular strips that overlap each other such that a single bone fastener is passed through two overlapping anchoring members to lock the two modular mesh strips together. Additional modular mesh strips can be added on at either end, as desired, to provide the desired length of dural coverage.
US08663295B2	Posterior spinal prosthesis A posterior spinal prosthesis is configured to cover exposed portions of a spinal column especially, but not necessarily, as a result of a medical spinal procedure and particularly, to provide posterior coverage of an exposed spinal cord, soft tissue, Foramen and/or adipose tissue, associated with one or more vertebrae as a result of the removal the spinous processes and/or the spinous process and laminar hoods from the one or more vertebrae of the spine as a result of a spinal decompression procedure or other reason. A plate forming the prosthesis is connectable to spine rod constructs implanted on lateral sides of the vertebrae and projects in the posterior direction relative to the connection. The plate is generally curved in the superior/inferior direction to provide either a lordotic or kyphotic curvature depending on the portion of the spine to which the prosthesis is utilized. As such, the posterior spinal prosthesis may be used on any portion of the spine such as the cervical vertebrae, the thoracic vertebrae and/or the lumbar vertebrae. The present posterior spinal prosthesis also provides posterior stabilization of the associated vertebrae as well as aiding in preventing post operative soft tissue cavitation at the decompression site.
US08663294B2	Apparatus and methods for vertebral augmentation using linked expandable bodies Implants and methods for osteopathic augmentation and repositioning of vertebrae may comprise a chain having one or more beads or bodies configured for insertion into a vertebral body. The one or more bodies may be expandable. As the chain is inserted into the vertebral body, it may fill a central portion thereof and can push against the inner sides of the endplates of the vertebral body, thereby providing structural support and tending to restore the vertebral body to its original height. The one or more bodies may have a first configuration dimensioned to pass through a catheter or other introducer, and may expand to a second, larger configuration after insertion into the bone in order to secure the chain within the bone.
US08663289B2	Pedicle screw head extender The present invention relates to pedicle screw spinal rod connectors and more specifically, a pedicle screw head extender for use with a pedicle screw to ease connection to a spinal rod. The pedicle screw head extenders provided herein can be used with either fixed head pedicle screws or multi-axial head pedicle screws. The pedicle screw head extenders can either be threaded to or snapped into place within the various pedicle screws. It may also be possible to use the present invention with other types of spinal screws that may be connected to spinal rods without the screw actually being implanted through the pedicle of the spine.
US08663286B2	Compliant dynamic spinal implant and associated methods A spinal implant comprises a plurality of contiguous segments, said plurality of contiguous segments configured to apply a torque to a degenerate spinal segment in any of three orthogonal axes. At least one mounting connection is configured to connect said spinal implant to a mounting mechanism, said mounting mechanism being configured to attach said spinal implant to said degenerate spinal segment.
US08663284B2	Spinal column stabilization system, connecting element for a spinal column stabilization system and method of manufacturing such a connecting element A connecting element for a spinal column stabilization system includes a first attachment section for fixing to a first bone attachment device, a second attachment section for fixing to a second bone attachment device and an at least partially flexible intermediate section. The intermediate section is arranged between the first and the second attachment section and is in the form of a strip-like, winding leaf spring element having at least one recess. A desired spring stiffness is maintained as precisely as possible, especially in the intermediate section independently of possible manufacturing tolerances arising from the manufacturing process. At least one of the two leaf spring element surfaces of the leaf spring element includes at least one stiffness-modifying element. The connecting element may be part of an improved spinal column fixation system and made by an improved method of manufacturing a connecting element.
US08663282B2	Advanced intra-spinal decompression implant A new intra-spinal decompression implant is introduced. One example for our presentation is a device with 2 or 3 pieces, with each piece with 2 clamps, symmetrically located on each side of each piece. The main piece has at least 2 screws which engage into 2 or more grooves in the side piece, to get attached to the side piece. The 3rd piece, as an optional piece, is the bottom piece, which is similar to the side piece, and gets attached to the main piece, using same or different screws. Each piece is attached to the human body, during back surgery, with corresponding clamps. This improves the quality of the surgery and the result for the patient. More examples are given here.
US08663279B2	Swivel anchor for knotless fixation of tissue A method and device for knotless fixation of tissue. A swivel anchor having a rotatable implant is used to capture suture for surgical tissue repair without requiring suture knots. The implant may be provided with a conical metal tip which is self-punching and avoids the need for pre-drilling a hole in bone. The implant includes a closed aperture to allow free sliding of a suture strand. The swivel anchor is secured in a hole in bone by advancing a fixation device, such as a cannulated interference screw, over the body of the implant.
US08663277B2	Braided barbed suture A suture assembly and a method for making the same is provided. The suture assembly includes a plurality of unbarbed filamentary elements intertwined with one another and at least one barbed filamentary element having a longitudinal axis and having plurality of barbs extending outwardly therefrom in a first direction less than 90 degrees from the longitudinal axis. According to exemplary embodiments, the at least one barbed filamentary may be intertwined along its length with the plurality of unbarbed filamentary elements, and the plurality of barbs extending outwardly beyond the unbarbed filamentary elements, or the primary outer periphery of the at least one barbed filamentary element may be contained within the intertwined unbarbed filamentary elements with the plurality of barbs extending through and outwardly from the plurality of unbarbed filamentary elements.
US08663272B2	Biodegradable adhesive film for vascular closure Devices and methods for sealing an opening in a blood vessel are disclosed. A device can include: an elongate, tubular non-stick outer sheath, the non-stick outer sheath having a distal end that is insertable into a vessel of a patient through the opening in the vessel wall, and having a proximal end remaining outside the patient; an elongate, tubular non-stick inner sheath disposed within the non-stick outer sheath; and an elongate, tubular adhesive film disposed between the non-stick outer sheath and the non-stick inner sheath, the adhesive film having both inward-facing and outward-facing adhesive surfaces and being supportable by the non-stick inner sheath during insertion into the vessel of the patient.
US08663269B2	Pivot tipped rod forceps A pivot tipped rod forceps instrument for surgical procedures is provided. The rod forceps has handle members attached at a pin. A pivoting jaw assembly having a pivoting tip is disposed at a distal end of each handle member. The pivoting jaw assembly is opened to receive a surgical rod or other object to be placed by the surgeon. The jaw assembly is then closed to engage the object. The pivoting tips are contoured to tightly engage the surgical rod. Once the rod is held by the tips, the whole pivoting jaw assembly can be rotated to a desired angle to aid the surgeon in manipulating the rod or other item as desired.
US08663268B2	Method for accessing the left atrial appendage with a balloon-tipped transseptal sheath A method for accessing the left atrial appendage with a balloon-tipped transseptal sheath is disclosed. A transseptal sheath is delivered to the left atrium through the intraatrial septum from the right atrium. The balloon tip may be inflated to prevent the transseptal sheath from falling proximally into the right atrium. The inflated balloon tip permits safe probing and exploration of the left atrial appendage and facilitates safe maintenance of the position of the transseptal sheath within the left atrial appendage while delivering an implantable device to the left atrial appendage.
US08663266B1	Device and method to protect needle localization wire A wire protector to cover an exposed portion of a device inserted into an organism comprises a removable backing layer removably joined to an attachment layer, and a transparent covering layer. The wire protector has a first end and a protector strip, the first end including a site wall and a connector wall, the site wall defining an insertion site therein, the site wall further comprising one or more prongs, the prongs facing the insertion site, the protector strip comprising one or more strip walls, such that when the backing layer is removed from the attachment layer, first end is positioned over the device insertion site, the protector strip is positioned over the exposed portion of the device, the protector device covers the exposed device portion. The wire protector stabilizes and protects needle localization wires used in breast biopsies, and can be used for other implanted devices. Also disclosed is a method for covering such exposed portion of such inserted device.
US08663264B2	Reciprocating rotary arthroscopic surgical instrument A surgical instrument includes a cutting member with an implement for cutting tissue, and a drive coupled to the cutting member to simultaneously rotate and translate the cutting member in response to a force applied to the drive. A method of cutting tissue includes positioning an outer member such that tissue is located within the outer member, engaging the tissue with an inner member, and simultaneously rotating and translating the inner member to cut the tissue. A tangential cutting force is applied to the tissue with the inner member to mechanically cut the tissue. The inner member is mechanically driven to undergo simultaneous rotation and translation.
US08663259B2	Rotational thrombectomy wire A rotational thrombectomy wire for breaking up vascular thrombus or other obstructive material having a core having a proximal portion and a distal portion. The distal portion has a smaller diameter than the proximal portion. A cable extends distally of the core. The cable has a first covering material positioned external thereof. A first coil is attached to a distal portion of the cable and has a diameter larger than a diameter of the cable and has a second covering material positioned thereover. The wire is rotatable by a motor.
US08663250B2	Suturing instrument with dual needles and method of passing suture An apparatus and method for passing suture in tissue repair and other surgical procedures. The apparatus includes a pair of jaws mounted on a distal end of a shaft, a handle assembly mounted on a proximal end of the shaft, and two needles mounted on the handle assembly and through a cannulation of the shaft. A dual-needle actuator communicates with the two needles. A suture is placed at the tip of the lower jaw. By advancing the dual-needle actuator relative to the body of the instrument, the two needles are pushed forward to capture the suture and advance it through the tissue to be sutured.
US08663247B2	Hemostatic clipping devices and methods A tissue clipping apparatus, comprises a flexible, elongate member, a proximal end of which remains external to the body accessible to a user while a distal end of the flexible member is inserted into the body to a location adjacent to target tissue to be clipped and a control wire extending through the flexible member in combination with a capsule releasably coupled to a distal end of the flexible member and a clip a proximal portion of which is received within the capsule. A joint releasably coupling the clip to the control wire, includes a yoke extending around a proximal end of the clip and a frangible link which fails when subject to a predetermined force to separate the clip from the control wire.
US08663246B2	Anastomosis instrument and method for performing same A method of deforming a plurality of surgical fasteners is provided. The method includes the step of providing a surgical instrument having a loading unit supporting the plurality of surgical fasteners in an array, the surgical instrument having a handle, a distal link, an intermediate link, and a proximal link. The method further includes the steps of moving the handle in a direction to pivot the intermediate link to a position in which the distal link, intermediate link, and proximal link have a fully-extended position, compressing a spring disposed adjacent the proximal link, deforming the surgical fasteners, moving the handle further in the direction, pivoting the intermediate link to another position in which the distal link, intermediate link, and proximal link have a deflected position and releasing the surgical fasteners from the loading unit.
US08663241B2	Device for full thickness resectioning of an organ A full-thickness resection system is disclosed. In an embodiment for the resection system, the system may include a flexible shaft, a flexible guide member disposed within the flexible shaft, a stapling mechanism disposed around the flexible guide member, and a grasper. The stapling mechanism has an elongated portion that is at least partially disposed within the flexible shaft. The stapling mechanism includes a stapling arm and an anvil arm. The stapling arm has a longitudinal axis and includes a stapling head having a longitudinal axis. The anvil includes an anvil head. The stapling arm and anvil arm extend from the elongated portion of the stapling mechanism and are moveable with respect to each other between a tissue receiving position and a stapling position. The grasper extends through the flexible shaft and is adapted to grasp a portion of a tissue that is to be excised from an organ in the patient's body. The grasper is movable on an axis that is perpendicular to the longitudinal axis of the stapling head.
US08663232B2	Apparatus and method for creating an implantation space in a spine An apparatus used in spinal surgery for creating a space of selected shape and dimensions across the disc space between adjacent vertebral bodies of the spine.
US08663231B2	Apparatus and methods for introducing portals in bone An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.
US08663229B2	Instruments and method for preparing an intervertebral space for receiving an artificial disc implant Instruments and methods for preparing an intervertebral space for receiving an implant. An adjustable trial implant has an adjustable stop mechanism having a stop member connected thereto to vary the distance that a body portion of the trial implant can move into the intervertebral space. Cutting tools for forming cutouts in the adjacent vertebrae use the trial implant and/or a guide to position a cutting tool which may be a burr or a chisel. The chisel cutting tool can be moveable relative to a selected trial implant or the chisel cutting tools can be fixed onto a trial implant shaped body portion.
US08663227B2	Single-unit cutting head systems for safe removal of nucleus pulposus tissue Single-unit cutting head systems for safe removal of nucleus pulposis tissue are provided. The cutting heads compose a part of the systems that are provided to address several problems, including clogging of state-of-the-art systems during removal of such tissue, for example. The target tissue can include any tissue that is accessible through a small surgical opening, for example, a joint tissue such as a meniscus or an intervertebral tissue, such as a nucleus pulposus. The devices can be referred to as orthopedic tissue removal devices having cutting heads associated with vacuum systems, making the systems useful in several procedures, including X-LIF (lateral approach to an intervertebral fusions) procedures, T-LIF (transforaminal approach to intervertebral fusions) procedures, P-LIF (posterior approach to intervertebral fusions), and a percutaneous, transforaminal approach (Kambin triangle access).
US08663222B2	Dynamic and static bipolar electrical sealing and cutting device An end effector assembly includes opposed jaws moveable from an open to a closed position for grasping tissue therebetween. Each jaw includes an electrically conductive surface adapted to conduct electrosurgical energy through tissue disposed between the jaws. A static bipolar cutting portion including at least one electrically conductive cutting element and at least one insulating element having a first configuration is disposed on at least one of the jaws. The static cutting portion is configured to electrically cut tissue disposed between the jaws upon activation of the cutting element and at least one of an opposing sealing surface and an opposing cutting element. A dynamic cutting portion including at least one electrically conductive cutting element and at least one insulating element having a second configuration is disposed on at least one of the jaws. The dynamic cutting portion electrically transects tissue during movement relative to tissue.
US08663214B2	Method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm A system for performing an electrosurgical procedure at a surgical site is disclosed. The system includes a sensor configured to continually sense an electrical and/or a physical property of tissue at a surgical site and to generate a sensor signal as a function thereof. The system also includes a control module configured to process the sensor signal using a processor, an algorithm, and a map having one or more predetermined values. The control module is further configured to compare the sensor signal to a predetermined level to determine reliability of the sensor signal and to signal an electrosurgical generator in response to a reliable sensor signal such that the electrosurgical generator enters energy control mode, wherein the electrosurgical generator matches an output of the control signal with a predetermined value from the map.
US08663205B2	Laser procedure for treatment of presbyopia and other eye disorders A segmented scleral expansion band adapted for implantation within or fastening to a segment of the sclera of an eye lying outside of and adjacent to the ciliary body of the eye, is formed from a number of arcuate segments, curved to match the curvature of the globe of the eye, and joined together at each end to form a complete scleral expansion band. The band is implanted in the sclera of the eye by forming circumferential tunnels, inserting the band segments through the tunnels, and joining the ends of the segments to form a complete scleral expansion band. The scleral expansion band is useful in treating presbyopia and other ocular disorders.
US08663204B2	Medical instrument comprising a separate transmitter unit which can be exteriorly fastened The invention relates to a medical instrument, comprising a signal transmitter and at least one activating device for activating the transmitter which is provided on a transmitter unit which is separate from the instrument, wherein the transmitter unit is a unit which can be fastened to the exterior of the instrument. It also relates to a method for controlling a treatment-assisting medical software by means of a signal transmitter which is arranged on a medical instrument, wherein the instrument is positionally detected by means of a medical tracking system, and wherein the software assigns a different significance to the signal output by the transmitter depending on the position of the instrument.
US08663200B2	Control circuit and method for negative pressure wound treatment apparatus A negative pressure wound therapy apparatus can include a wound dressing, a fluid collection container, a vacuum pump comprising a pump motor, and tubing. Additionally, the apparatus can include a pressure sensor that measures a pressure in the tubing. One or more tubes can channel a fluid between the wound dressing, the fluid collection canister, and the pump. In addition, first and second control circuits can be provided for controlling the pump motor without using a processor. The first control circuit can generate a difference signal between a desired pressure input and a pressure sensor input, and can further generate a motor control signal responsive to the difference signal. Moreover, a second control circuit can provide an override signal based at least in part on the difference signal and at least one reference signal. The override signal beneficially overrides the motor control signal to prevent the pump motor from stalling.
US08663197B2	Flexible channel for use on endoscope A flexible channel to be incorporated into an endoscopic insertion portion having a flexible portion at least in part of its length, for the purpose of providing a flexible passage internally of the endoscopic insertion portion. The flexible channel is composed of a flexible tube with a helical groove on and around its outer periphery, and a reinforcing coil fitted in the helical groove on the flexible tube. At the root of the helical groove, angular projections are formed at intervals in the longitudinal direction and the reinforcing coil is tightly pressed tightly against the angular projections.
US08663195B2	Rotational atherectomy device with fluid inflatable support elements and distal protection capability A rotational atherectomy device for abrading a stenotic lesion from a vessel of a patient comprises a flexible drive shaft which extends towards a distal end of the device, a distal fluid inflatable support element located at a distal end of the drive shaft and an abrasive element mounted to the drive shaft proximal to and spaced away from the distal fluid inflatable support element. Both the abrasive element and the distal fluid inflatable support element are rotatable together with the drive shaft.
US08663194B2	Intraocular drug delivery device and associated methods The present invention provides devices, systems, and methods for delivery of an active agent into the eye of a subject. In one aspect, for example, an ocular active agent delivery device (10) can include an active agent reservoir (14) disposed in an annular housing (12), the annular housing (12) being configured to fit inside of a lens capsule and at least partially encircling a line of sight of an intraocular lens within the lens capsule. The device (10) can further include a semipermeable membrane (16) operatively coupled to the active agent reservoir (14), where the semipermeable membrane (16) is configured to allow diffusion of an active agent from the active agent reservoir (14). Additionally, a valve (18) can be operatively coupled to the active agent reservoir (14), where the valve (18) is configured to allow filling of the active agent reservoir (14) with an active agent.
US08663193B2	Disposable injector with a manually actuated piston and with a twin chamber system A method for preparing a solution from a solvent and an active substance in and on a disposable injector with a housing, with an at least intermittently fillable cylinder/piston unit which is arranged thereon and has a manually movable piston, and with a detachable container adapter mounted upstream of the cylinder/piston unit, wherein the container adapter supports a container which can be filled at least temporarily with active substance and which is closable by an openable stopper.
US08663192B2	Devices and methods for treating pain associated with tonsillectomies Described here are devices and methods for treating one or more conditions or symptoms associated with a tonsil procedure. In some variations, a drug-releasing device may be at least partially delivered to one or more tonsillar tissues before, during, or after a tonsil procedure. In some variations, the drug-releasing device may be configured to be biodegradable. In other variations, the drug-releasing device may comprise one or more hemostatic materials or one or more adhesives. The drug-releasing device may be configured to release one or more drugs or agents, such as, for example, one or more analgesics, local anesthetics, vasoconstrictors, antibiotics, combinations thereof and the like.
US08663190B2	Expandable catheter system for peri-ostial injection and muscle and nerve fiber ablation At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension.
US08663185B2	Wearing article The present invention aims to provide a wearing article improved so that various types of nonwoven fabrics can be effectively used for target nonwoven fabric without anxiety that the target nonwoven fabric once engaged with hook elements might be readily torn. As an outer sheet 8 defining a garment-facing side of a chassis 2, a commonly-used nonwoven fabric is used and this nonwoven fabric is oriented in a longitudinal direction Y. Rear waist region's side edges 14 of the chassis 2 are provided with flaps 16 attached thereto. Each of the flaps 16 has a joint region 19 along which the flap 16 is joined to the chassis 2 and first and second hook elements 21, 22. Between the joint region 19 and the first and second hook elements 21, 22 as viewed in the transverse direction X, a contractible region 23 adapted to be contractible in the transverse direction X. The contractible region 23 is provided with a plurality of flap's elastic members 24. The joint region 19 provided with none of the flap's elastic members 24 define a non-contractible region. The first and second hook elements 21, 22 of the flap 16 may be put in engagement with the outer sheet 8 to connect the front and rear waist regions 4, 5 to each other in a circumferential direction.
US08663183B2	Absorbent articles with comfortable elasticated laminates A disposable absorbent article is claimed that comprised a backsheet and an absorbent core and a core coversheet or topsheet, that in use faces the wearer, and one or more cuffs (25, 26), comprising one or more longitudinally extending elastic laminate portion(s) (10), formed by at least an elastic material (12) attached to a supporting sheet (20) of said cuff (25, 26), said laminate portion(s) (10) comprising in at least relaxed and partially contracted state a body-facing surface with a multitude of wrinkles, and whereby said elastic laminate portion (10) has an absolute contracted length Lc and a fully stretched absolute length Ls, whereby at a partial elongation of the elastic laminate potion (10) of ε=0.5: a) said wrinkles have an average wrinkle height Hw of less than 600 micrometers; and b) said laminate portion (10) has an average wrinkle density Dw between 5 and 10 wrinkles per cm.
US08663179B2	Wound treatment system and method of use A wound treatment system including a treatment chamber, a source of an aqueous antibiotic, a source of an oxygen-enriched gas, and a control system adapted to alternately surround a human limb with antibiotic mist and the oxygen enriched gas, which can be used to heal lesions such as foot ulcers. A method of treating lesions such as foot ulcers is also disclosed, that includes bathing the lesion in antibiotic mist and contacting it with oxygen gas.
US08663178B2	Reinforced stocking or sock for the prevention and/or treatment of hallux valgus A stocking or sock with a foot portion includes a pocket for containing the big toe that is separate from the pocket(s) for the other toes. At least one medial reinforcement, integrally attached to the foot portion, entirely or partially surrounds the big toe pocket, while the medial part of the foot portion, and the posterior part or heel of the foot portion are anchored to the posterolateral or lateral part of foot portion, coming to bear on the anterior part of said pocket, counteracting any lateral deflections, and on the medial part, corresponding to the metatarsophalangeal joint and the first metatarsal of the foot, counteracting any medial deflections.
US08663174B2	Hub assembly having a hidden needle for a drug delivery pen A hub assembly for a pen injection device allows a needle to be disposed in at least one of a plurality of positions prior to an injection. A hub of the hub assembly is connected to the pen injection device, and the needle is received by the hub. A shield is movably connected to the hub and allows the needle to be disposed in at least one of several positions prior to an injection, such as a position in which the needle is visible for priming and a position that prevents the needle from being visible. A tab connected to the hub is received by a channel formed in the shield to control movement of the shield.
US08663170B2	Rotating valve assembly including multi-lumen spherical valve A valve assembly includes a valve housing having an upper body portion and a lower body portion that define an internal chamber for accommodating a valve member. The housing has axially aligned inlet and outlet ports. The valve assembly includes a generally spherical valve member seated within the internal chamber that defines first and second bores. The first bore defines a first longitudinal axis and the second bore defines a second longitudinal axis offset relative to the first longitudinal axis. The valve member is mounted for movement between a first position and a second position. The valve assembly includes a caroming mechanism for moving the valve member between the first position and the second position, including cam surfaces formed on the exterior surface of the valve member and a cam pin formed on the interior surface of the upper body portion of the housing.
US08663169B2	Needle for bloodless IV An intravenous catheter system having a retractable needle system and a body system is disclosed. The retractable needle system includes a housing, a needle, a docking feature, and an optional anti-shearing mechanism. The body system includes a body, at least one hub, a catheter connector, at least one plug, a plug recoil mechanism, a locking mechanism, a flash chamber, and a flash window.
US08663166B2	Powerhead control in a power injection system A dual head contrast media injection system performs a patency check or test injection, determining flow rate and/or flow volume from the programmed protocol. The tubing that connects syringes to a patient shares only a short common section near to the patient. Appropriate injection steps are taken to compensate for tubing elasticity. A wireless remote control and a touch screen control are provided, improving functionality and information delivery. The display brightness is controlled based on the ambient light, and the display panel includes a double swivel permitting re-orientation. The orientation of the display may also be controlled based on, e.g., the current step, the tilt angle of the powerhead, or a manual control. Furthermore, the display is customizable to identify the type of fluid (contrast, saline, etc.) on either side of the injector, to provide matched color coding, and to provide a folder/tab analogy for retrieving injection protocol parameters.
US08663161B2	Neonatal fluid tubing heater A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.
US08663160B2	Device to indicate priming of an infusion line A priming indicator for a fluid infusion system includes a luer cap or other component of the infusion system having an indicator surface covered by a membrane. The membrane exhibits a first visual characteristic, such as being opaque, when dry and exhibits a second characteristic, such as becoming less opaque, when wet. Once the membrane becomes wet, indicia on the surface, which may be provided on a rod at least partially covered by the membrane, becomes visible, thereby indicating an intravenous tube to which the luer cap is secured has been primed or is nearly primed. The indicator may alternately be employed at an upstream end of an infusion set, such as at the port of a medical bag providing a supply of fluid, to indicate a low level of fluid in the medical bag.
US08663158B2	Needleless injector drug capsule and a method for filling thereof A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules.
US08663156B2	System and method for providing servo-controlled resuscitation The present invention provides a system and method for controlling resuscitation in a patient. In at least one embodiment, the invention includes a fluid rate measurer, a controller electrically coupled to the fluid rate measurer, and a pump. The controller is adapted to receive signals from a physiological monitor and controls the pump.
US08663155B2	Transdermal drug delivery devices having coated microprotrusions A device (12) and method are provided for percutaneous transdermal delivery of a potent pharmacologically active agent. The agent is dissolved in water to form an aqueous coating solution having an appropriate viscosity for coating extremely tiny skin piercing elements (10). The coating solution is applied to the skin piercing elements (10) using known coating techniques and then dried. The device (12) is applied to the skin of a living animal (e.g., a human), causing the microprotrusions (10) to pierce the stratum corneum and deliver a therapeutically effect dose of the agent to the animal.
US08663154B2	Electrosurgical method and system for treating foot ulcer An electrosurgical method for treating foot ulcer, including diabetic foot ulcer, comprising: positioning an active electrode in close proximity to the ulcer, the active electrode being disposed on a distal end of an electrosurgical shaft; applying a high-frequency voltage potential difference across the active electrode and a return electrode in the presence of an electrically conductive fluid, the voltage potential being sufficient to generate plasma at the active electrode; and stimulating the ulcer with the active electrode to increase blood flow, remove unhealthy tissue and induce the body's natural healing response.
US08663148B2	Device and method for restoration of the condition of blood The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.
US08663145B2	Myofascial strap A method of treating a patient with a strap is provided. The method includes providing a strap including a retainer portion, a base portion opposing the retainer portion, a foam layer having a first surface, and a fabric layer having a second surface, the foam layer having an elasticity greater than the fabric layer, contacting a body portion of a patient with the first surface, and retaining the strap against the body portion by connecting the retainer portion to the second surface.
US08663144B2	Modular compression device and method of assembly An apparatus for applying pressure to a body part comprising multiple interconnectable bands of compressible or noncompressible material. Optional spine to further interconnect the bands. Interconnectable pieces designed for covering specific body areas. Modular arrangement of the individual components. Customized or off-the-shelf availability of the apparatus.
US08663140B2	Analgesic implant device and system Techniques associated with an implant system for imparting vibratory massage to tissue within a body is disclosed. Methods include placing an implant device near tissue in a pelvic region, the implant device configured to produce and communicate a vibration to the tissue, the implant device including a case forming a portion of an exterior of the implant device and defining an interior of the implant device, a vibration generator mounted on the case to vibrate the implant device, and a tissue engaging structure located on the exterior surface of the case to engage the tissue, and activating the vibration generator of the implant device to cause the implant device to vibrate against the tissue, wherein the vibration stimulates a nerve to treat sexual dysfunction.
US08663138B2	Data handling for high frequency chest wall oscillation system A HFCWO apparatus includes a housing having a port, a therapy system carried by the housing and operable to deliver HFCWO therapy to a patient in accordance with a set of operating parameters, and a memory device couplable to the port for storing at least a portion of the set of operating parameters. The therapy system may be operable in accordance with the portion of the set of operating parameters stored in the memory device. The apparatus may comprise a wireless transmitter carried by the housing and operable to wirelessly transmit data relating to HFCWO therapy to a wireless device, such as a printer, PC, a PDA, and the like.
US08663135B2	Belt buckle device In a belt buckle device including a tongue piece (75, 76; 210; 310) connected to an end of a belt extending in a longitudinal direction and a hook member (68, 70; 220; 320) configured to be selectively connected to the tongue piece by engaging a first lateral bar of the tongue piece in a hook opening (111; 226; 326) defined by a hook portion (71, 72; 225; 324) thereof, a longitudinal dimension (B) between the free end of the tongue piece and a base end side of the first lateral bar is substantially equal to or smaller than a width (A) of the entrance of the hook opening, and the effective thickness (C) of the first lateral bar is greater than the width (A) of the entrance of the hook opening. Thus, the first lateral bar is held inside the hook opening as long as the tongue piece is kept in a flat position in a reliable manner. In particular, the first lateral bar can be freely introduced into the hook opening simply by raising the base end of the tongue piece while the first lateral bar is applied to the entrance of the hook opening so that the belt buckle device can be readily fastened even when the belt buckle device cannot be viewed from a proper viewing angle. Also, the belt buckle device can be readily fastened with a minimum dexterity requirement and very quickly.
US08663134B2	Walking assistance device In a walking assistance device (10) including a main frame (22) supporting a power generator (26, 28) and worn on a pelvic part of a user, the main frame is provided with an opening (23) in a middle part thereof, and an electronic unit (25) is received in the opening. As the electronic unit is placed in the middle part of the main frame which is relatively free from deformation, the electronic unit is protected from deformation or stress that could impair the reliability of the electronic unit. To achieve both an easy access to the electronic unit, and an attractive appearance, the opening may be provided with a lid (24) that selectively closes the opening from a side adjacent to the user, and the lid may be formed as a back support member for supporting a back part of the user. As the lid serves the dual purposes, the weight and cost of the device can be minimized. For the convenience of the handling of the lid, the lid may be supported by the main frame via a hinge (121) provided adjacent to an upper or lower part of the opening.
US08663132B2	Reduced-pressure treatment systems and methods employing a variable cover A system, dressing, and method for providing reduced pressure treatment to a tissue site on a wound bed of a patient includes a variable wound dressing having a variable cover that is pliable at ambient pressure and less-pliable when placed under reduced pressure. The variable wound dressing has a first side and a second, patient-facing side, and in use, a treatment space is formed between the second, patient-facing side of the variable dressing and the wound bed. One or more ports are used to supply reduced pressure within the variable cover and to the wound site. A reduced-pressure subsystem is also included that is operable to supply reduced pressure to the one or more ports.
US08663131B2	Tongue strength evaluation system and method An apparatus for evaluating the tongue strength of a subject during a sucking event includes an insert positioned within a nipple element to provide an output in response to deformation of the nipple element during a sucking event. The output is at least one of resistive force exerted against the subject's tongue and movement measurement of deformation force exerted on the nipple element during the sucking event. The apparatus is configurable to evaluate nutritive sucking (NS) or non-nutritive sucking (NNS) capabilities of the subject. The insert may be a sensing device, a compliance element, an intermediate device or a combination of these. A coupling device is configured to position the insert relative to the nipple element and/or to receive output from the insert. A method includes evaluating tongue strength of a subject during NS or NNS and using inserts providing increasing levels of resistive force to exercise the subject's tongue.
US08663119B2	Wrist sphygmomanometer A wrist sphygmomanometer includes an operation unit operable by a user. A manometer measures blood pressure. A detector detects the posture of the user. A storage stores an optimum posture for the user. A comparator compares the posture detected by the detector and the optimum posture stored beforehand in the storage to generate posture information. A communication unit communicates the posture information to the user. A setting unit sets the optimum posture in the storage. The storage includes a first storage section, which stores a fixed optimum posture corresponding to an unspecified user, and a second storage section, which stores a second optimum posture corresponding to a specified used. The setting unit stores the second posture based on a value detected by the detector as the second optimum posture in the second storage section in accordance with an operation of the operation unit.
US08663117B2	System and method for diagnosing a fluid status of a patient A system and method for diagnosing a fluid status of a patient includes non-invasively determining a left ventricular pressure of blood within a left ventricle of a heart of the patient. The left ventricular pressure is compared to a predefined pressure value to diagnose the fluid status.
US08663116B2	Methods, assemblies, and devices for positioning a catheter tip using an ultrasonic imaging system A catheter assembly includes an elongated member having an ultrasonic beacon disposed adjacent to a distal end portion of the elongated member, a power supply releasably attachable adjacent to the proximal end of the elongated member, and a catheter. The distal end portion of the elongated member with the ultrasonic transmitter is inserted into an anatomical structure of the human body, and the ultrasonic transmitter is powered by the power supply. Using conventional medical ultrasonography equipment, a technician is able to observe and/or track on a display an image of the internal structure of the human body and an image such as an illuminated bright spot representing the energized ultrasonic beacon. After locating the elongated member, the power supply is removed, and the catheter is slid onto the elongated member to locate the catheter tip. Thereafter, the elongated member is removed.
US08663112B2	Methods and systems for fat reduction and/or cellulite treatment A method can include targeting a region of interest below a surface of skin, which contains fat lobuli and delivering ultrasound energy to the region of interest. The ultrasound energy generates a conformal lesion with said ultrasound energy on a surface of a fat lobuli. The lesion creates an opening in the surface of the fat lobuli, which allows the draining of a fluid out of the fat lobuli and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.
US08663110B2	Providing an optimal ultrasound image for interventional treatment in a medical system Embodiments for providing an optimal ultrasound image for interventional treatment in a medical system are disclosed. In one embodiment, by way of non-limiting example, a medical system comprises: a medical device that is inserted into a target object and configured to remove a lesion within the target object; an ultrasound data acquisition unit configured to transmit and receive ultrasound signals to and from the target object to output ultrasound data; and a processing unit in communication with the ultrasound data acquisition unit, the processing unit being configured to form a plurality of ultrasound images based on the ultrasound data and perform an image processing upon each of the ultrasound images to detect a position of the medical device.
US08663108B2	Method and system for rapidly and passively identifying changes in number of open pores in the skin of an individual In one aspect, there is disclosed a system and method for rapidly and passively identifying changes in the number of open pores in the skin of an individual in response to a stimulus without contacting the individual. This is accomplished by using a thermal camera that is sensitive in the mid-wave or long-wave infrared (3-5 or 8-14 μmeters) to observe and/or count the number of skin pores opening in response to questions being asked of the individual.
US08663106B2	Non-invasive temperature monitoring device A monitoring system comprises a module having at least one sensor and preferably skin and ambient temperature sensors within a housing. The device may be durable or disposable. The housing may be provided with certain surface features and shapes to facilitate mounting on and interface with the skin of the wearer for more accurate temperature measurement. A receiver may be provided to obtain and display data from the module. The module may also display the output data. The output data comprises both detected and derived data relating to physiological and contextual parameters of the wearer and may be transmitted directly to a local recipient or remotely over a communications network. The system is capable of deriving and predicting the occurrence of a number of physiological and conditional states and events and reporting the same as output data.
US08663104B2	Disease management system and method including therapeutic alterations permission level A system and method for allowing a patient to access an automated process for managing a specified health problem called a disease. The system performs disease management in a fully automated manner, using periodic interactive dialogs with the patient to obtain health state measurements from the patient, to evaluate and assess the progress of the patient's disease, to review and adjust therapy to optimal levels, and to give the patient medical advice for administering treatment and handling symptom flare-ups and acute episodes of the disease. The medical records are updated, the progression of the disease is stored and tracked, and the patient's preferences for treatment are stored and then used to offer medical advice based on the current state of the disease. A prestored general disease trend curve is compared against a patient specific disease trend curve, and the system makes an automated response such as adjusting therapy.
US08663100B2	Surgical access system and related methods A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
US08663095B2	Marker and guide sheath system for endoscopic treatment tool A marker to be attached to an endoscopic treatment tool for precisely directing a tip of the treatment tool to a target site with no additional physical burden to the patient is provided. A marker 1 used in an endoscopic treatment tool to be inserted in a guide sheath, the marker including: a body 2; and a tip section 4A for removably fixing the body 2 to a middle section of the endoscopic treatment tool, wherein the distance between the body 2 and a tip of the endoscopic treatment tool can be determined freely.
US08663094B2	In-vivo information acquiring system An in-vivo observation system provided with a capsule endoscope including an in-vivo observation section, a battery, a magnetic field detection section, a power supply switch that controls a power supply and a power supply control section that causes the power supply switch to operate according to an internal signal from the magnetic field detection section, and a magnetic field generating apparatus including a magnetic field generating section, an operation section that outputs an operation signal according to an operation by a user and a masking section that masks an operation signal inputted to the magnetic field generating section for a predetermined period.
US08663091B2	Medical robotic system having entry guide controller with instrument tip velocity limiting A medical robotic system includes an entry guide with articulatable instruments extending out of its distal end, an entry guide manipulator providing controllable four degrees-of-freedom movement of the entry guide, and a controller configured to limit joint velocities in the entry guide manipulator so as to prevent movement of tips of the articulatable instruments from exceeding a maximum allowable linear velocity when the entry guide manipulator is being used to move the entry guide.
US08663088B2	System of accessories for use with bronchoscopes A clip or flexible handles extension facilitate simultaneous retention and operation of a bronchoscope and associated bronchoscopic tools held in one hand to allow operation by a single practitioner. Also provided is an adapter for the connection port of the working channel of a bronchoscope which performs both sealing and tool-locking functions. Also disclosed is a guide sheath arrangement with a reduced flexibility proximal portion to facilitate insertion of tools into the guide sheath.
US08663085B2	Methods, devices and systems for counterpulsation of blood flow to and from the circulatory system Counterpulsation methods and systems for assisting the heart of a patient involve, for example, coordinating the operation of a pulsatile pump to suction blood from an artery through a blood flow conduit while the heart is in systole and expel the blood into the blood flow conduit and the artery while the heart is in diastole.
US08663083B2	System, method, computer-readable medium, and use for planning combined therapy A system and method for planning a necrosis-inducing therapy and subsequent administration of a necrosis-targeting agent are described. The system takes into account the effect of necrosis-induction therapy as a basis for the biodistribution estimate of the necrosis-targeting agent. This interaction between the different calculation steps is essential for an accurate planning result. A computer-readable medium and use are also provided.
US08663080B2	Apparatus for forming aseptic containers An apparatus for obtaining containers from a sheet material includes an operating unit for processing the sheet material. The operating unit includes an upper operating part for interacting with an upper surface of the sheet material and a lower operating part for interacting with a lower surface of the sheet material. The apparatus further includes a sterilizing arrangement for sterilizing a space adjacent to the upper operating part and to the lower operating part, so as to create a substantially aseptic environment above and below the sheet material.
US08663074B2	Exercise apparatus with a pull cord central pulley attached to a carriage and a pulley locking mechanism An exercise apparatus including a frame, a carriage, a central pulley, first and second frame pulleys, a pull cord, and a locking mechanism. The frame defines a longitudinal axis. The carriage is mounted on the frame and movable along the longitudinal axis. The central pulley is attached to the carriage. The first and second frame pulleys are attached to the frame. The pull cord has first and second handle portions. The pull cord is looped about the pulleys. The central pulley is between the first and second frame pulleys along the pull cord. The first frame pulley is between the first handle portion and the central pulley along the pull cord. The second frame pulley is between the second handle portion and the central pulley along the pull cord. The locking mechanism is configured to engage the central pulley.
US08663072B2	Exercise apparatus with flexible element An exercise device includes first and second coupling systems at each comprise a flexible element. In one implementation, the exercise device further comprises a step height adjustment mechanism. The flexible element of the first and second coupling systems couples at least one crank to a right foot support and a left foot support. The step height adjustment mechanism allows a person to adjust a step height of a path through which the left and right foot supports move.
US08663071B2	Device and method for limiting travel in an exercise device, and an exercise device including such a limiting device A method and/or a device may limit a distance traveled by a treadle assembly in an exercise device. For example, the distance traveled by the treadle assembly may be limited by limiting a distance that a resistance element operably coupled to the treadle assembly may travel. An exercise apparatus may include a travel-limiting device or capability.

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