Document Document Title
US08609715B2 Heteroarylcarboxylic acid ester derivative
Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
US08609706B2 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
US08609701B2 Pirfenidone treatment for patients with atypical liver function
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.
US08609700B2 Pyridine compounds for controlling invertebrate pests I
The present invention relates to novel pyridine compounds of the formulae I and II, to their salts, to their tautomers, to their N-oxides, and to the salts of these N-oxides or tautomers. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests. The invention also relates to a method for controlling invertebrate pests by using these compounds. The invention further relates to plant propagation material and to agricultural compositions comprising said compounds. wherein A is a radical of the formulae A1 or A2 # denotes the binding site to the remainder of formulae I or II; n is 0, 1, 2 or 3; Z is O, S or N—RN; X1 is S, O or NR1a; X2 is OR2a, NR2bR2c, S(O)mR2d; X3 is a lone pair or oxygen; R1, R2 and R3 are, inter alia, hydrogen, and RA and RN, are as defined in claim 1.
US08609691B2 Cyclohexylamin isoquinolone derivatives
The invention relates to 6-cyclohexylamine-substituted isoquinolone derivatives of the formula (I) or isoquinoline derivatives of the formula (I′) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
US08609688B2 Substituted imidazopyridinyl-aminopyridine compounds
The present invention relates to substituted imidazopyridinyl-aminopyridine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazopyridinyl-aminopyridine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
US08609687B2 Triazolopyridine JAK inhibitor compounds and methods
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.
US08609682B2 Analgesic agents
The invention provides a compound of formula (I) or a salt thereof, as well as compositions comprising such compounds. The compounds and compositions are useful as analgesics.
US08609681B2 Spirocyclic nitriles as protease inhibitors
The invention relates to substituted carbo- and heterocyclic spiro compounds of the formula Ia which inhibit thiol proteases, to processes for their preparation and to the use thereof as medicaments.
US08609679B2 2,4-diaminopyrimidines useful as kinase inhibitors
The present invention provides 2,4-diaminopyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same.
US08609675B2 Fused Tricyclic Compounds as novel mTOR inhibitors
The present invention provides Fused Tricyclic Compounds of the Formula (I) wherein Q, R1, R2, R3, and R4 are as defined herein, and pharmaceutically acceptable salts of such Fused Tricyclic Compounds. The Fused Tricyclic Compounds are useful in the treatment of cancer and other proliferative disorders.
US08609673B2 Vandetanib derivatives
This invention relates to novel quinazoline derivatives of the formula: wherein each variable is as defined herein, and their acceptable acid addition salts. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by inhibitory activity against the VEGF receptor tyrosine kinase.
US08609668B2 Substituted triazolo[1,5-A]pyrimidines as antiviral agents
A pharmaceutical composition comprising an effective amount of a compound of formulas (I-III) and a pharmaceutically acceptable carrier. Methods for treating a hepatitis virus in a patient comprising administering an effective amount of the compound of formulas (I-III) are also presented.
US08609666B2 2-morpholino-pyrido[3,2-D]pyrimidines
This invention relates to compounds of Formula (I) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other diseases like cancers.
US08609665B2 Solvate and crystalline forms of carbamoyl-cyclohexane derivatives
The present invention relates to novel solvate and crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel solvate and crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl]-cyclohexyl}-3,3-dimethyl-urea hydrochloride. Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described.
US08609664B2 Piperazinyl derivatives as modulators of chemokine receptor activity
The present application describes modulators of MIP-1α of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein m, T, W, R1, R4, R5, R5a and R5b are as defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using said modulators are disclosed.
US08609661B2 Pyrimido-pyrrolo-quinoxalinedione inhibitors of cystic fibrosis transmembrane conductance regulator protein and uses therefor
Provided herein are pyrimido-pyrrolo-quinoxalinedione (PPQ) compounds, and compositions comprising these compounds, that inhibit cystic fibrosis transmembrane conductance regulator (CFTR) mediated ion transport and that are useful for treating diseases and disorders associated with aberrantly increased CFTR chloride channel activity. The compounds, and compositions comprising the compounds, described herein are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased CFTR activity, for example, polycystic kidney disease. The compounds may be used for inhibiting expansion or preventing formation of cysts in persons who have polycystic kidney disease.
US08609659B2 Substituted 3,8-diazabicyclo[3.2.1]octane compounds
Diazapolycyclic compounds having affinity for the opioidergic receptors, preferably for the delta opioidergic receptors, with central and/or peripheral activity, having formula: A1-D1-T1  (I) wherein: A1 is a group of formula (II): wherein: R1 is phenyl wherein one of the ring hydrogen atoms is substituted with a group selected from C(O)R′, C(O)OR′, C(O)NHR′ or C(O)NR3R4, R′, R3 and R4, being as defined in the application; R2 is phenyl, optionally substituted D1 is a diazapolycyclic group T1 is a group selected from H, alkyl, alkenyl, alkynyl and from the following optionally substituted groups: cycloalkyl, heterocycloalkyl, aryl, heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, arylalkyl or heteroarylalkyl, and their hydrates and solvates and pharmaceutically acceptable salts.
US08609652B2 Method of administering a methylene blue-curcumin analog for the treatment of alzheimer's disease
A method of administering a methylene blue-curcumin hybrid useful in treating or preventing Alzheimer's Disease.
US08609649B2 Compositions and methods for the diagnosis, treatment, and prevention of amyotrophic lateral sclerosis and related neurological diseases
One aspect of the invention relates to a method of treating or preventing a neurodegenerative disease, comprising the step of administering to a patient in need thereof a therapeutically effective amount of an inhibitor of the formation of advanced glycation end products. Another aspect of the invention relates to a proteasome activity-based screening assay to select compounds which may be useful for treating or preventing a neurodegenerative disease, and the materials used therein. Yet another aspect of the invention relates to molecules, and methods of use thereof, which bind at or adjacent to SOD-I Trp32, including molecules that bind in a site adjacent to SOD-I Trp32 whether or not it is oxidized, for treating or preventing neurodegenerative disease.
US08609646B2 Enhanced erythropoiesis and iron metabolism
The present invention relates to methods and compounds for decreasing the expression of hepcidin, a protein associated with regulation of iron metabolism.
US08609639B2 Stat3 inhibitor having anti-cancer activity and methods
A small-molecule Stat3 dimerization inhibitor, S3I-M2001, is described and the dynamics of intracellular processing of activated Stat3 within the context of the biochemical and biological effects of the Stat3 chemical probe inhibitor are elucidated. S3I-M2001 is a newly-identified oxazole-based peptidomimetic of the Stat3 Src Homology (SH) 2 domain-binding phosphotyrosine peptide that selectively disrupts active Stat3:Stat3 dimers. Stat3-dependent malignant transformation, survival, and migration and invasion of mouse and human cancer cells harboring persistently-activated Stat3 were inhibited by S3I-M2001. S3I-M2001 inhibited Stat3-dependent transcriptional regulation of tumor survival genes, such as Bcl-xL. The disclosed compound is useful as a new potential treatment for certain cancers.
US08609637B2 Prodrugs of 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-(1H)-one and derivatives thereof
A prodrug can have a structure of Formula 10 or derivative thereof or stereoisomer thereof or pharmaceutically acceptable salt thereof. The prodrug can be included in a pharmaceutical composition for use in treatment of fungus, cancer, dermatitis, superficial mycoses; inflammation, tinea pedis, tinea cruris, and tinea corporis, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis, candidiasis (moniliasis), Candida albicans, tinea (pityriasis) vesicolor, Malassezia furfur, acute myeloid leukemia, acute lymphoid leukemia, chronic myelogenous leukemia, lymphoma or multiple myeloma.
US08609634B2 Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and related methods. In one embodiment, the pharmaceutically-acceptable salt is sodium hyaluronate. In another embodiment, the cationic preservative includes benzalkonium chloride (BAK).
US08609633B2 Core 2 GlcNAc-T inhibitors
A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective amount of an inhibitor of core 2 GlcNAc-T of formula I to a patient in need thereof wherein: R1 is H, C1-6 alkyl, C1-6 hydroxyalkyl, C1-6 alkoxy or C1-6-alkoxy-C1-6-alkyl; R2 is H, —OH or C1-6 alkoxy; S1 and S2 are independently selected saccharide moieties; and Z is a steroid moiety; or a pharmaceutically acceptable salt, ether or ester thereof.
US08609630B2 Vitamin B12 compositions
This disclosure provides compositions of vitamin B12, and methods of treatment or amelioration of a disease associated with vitamin B12 deficiency. The composition can take the form of a solid, semi-solid, gummy, or chewable lozenge. The composition can also take the form of a troche, a candy, a wafer, an orally disintegrating tablet, a sublingual tablet, a buccal tablet, a buccal patch, an oral dissolvable film, an aerosol or spray, a lip balm, and chewing gum.
US08609626B2 NLK as a marker for diagnosis of liver cancer and as a therapeutic agent thereof
A novel marker for diagnosis of liver cancer and use thereof are provided. To be specific, a marker for diagnosis of liver cancer using over-expression of NLK (neuro-like kinase) in liver cancer cell is provided, along with a composition for diagnosis of liver cancer, a kit, a microarray, and a method for diagnosing liver cancer using the marker. Additionally, a method for screening a substance to prevent or treat liver cancer by decreasing expression of the marker gene or protein, and a composition for preventing or treating liver cancer including such substance are provided. Accordingly, the NLK gene can be efficiently used as a target for diagnosis and treatment of liver cancer.
US08609624B2 Methods and compositions for the inhibition of Stat5 in prostate cancer cells
The present invention relates to compositions and methods for the treatment of prostate cancer. In certain embodiments, the invention relates to compositions and methods for the inhibition of prostate cancer cell growth, comprising inhibiting the activity of Stat5 in prostate cancer cells.
US08609618B2 Topical palmitoyl glutathione formulations
A topical composition for application to aging skin, comprising an effective amount of S-acyl glutathione derivative of formula (I) wherein R1 consists of an unsaturated or saturated C16 group and R2 is a hydrogen, aliphatic or aromatic acyl group; and a dermatologically acceptable carrier. Preferred compositions comprise about 1.0% to about 3.0% by weight of S-palmitoyl glutathione.
US08609617B2 KLF family members regulate intrinsic axon regeneration ability
This invention relates, to a method for promoting CNS axon regeneration, comprising (1) inhibiting the expression or activity in a neuron of one or more of the members of the Krüppel-like transcription factor (KLF) family that suppress axon growth (e.g., KLF 1, 2, 3, 4, 5, 9,12, 13, 14, 15 and/or 16), and/or (2) stimulating the expression or activity in a neuron of one or more of the members of the KLF family that promote axon growth (e.g., KLF 6 and/or 7).
US08609616B2 Strontium-containing compounds for use in the prevention or treatment of necrotic bone conditions
A method for the treatment and/or prophylaxis of an osteonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).
US08609615B2 Methods and compositions for treatment of myotonic dystrophy
In certain embodiments, the present invention provides compositions and methods for treating myotonic dystrophy.
US08609611B2 Synthesis of small particles
The invention provides an apparatus for forming fine particles of a substance in a precipitation chamber, in which the apparatus has means to convey the fine particles from the precipitation chamber to at least one particle collection chamber, downstream of the precipitation chamber, the particle collection chamber having an inlet and an outlet separate from the inlet. The invention also provides a method of forming fine particles of a substance, the method comprising contacting a non-gaseous fluid containing the substance with a dense fluid to expand the non-gaseous fluid in a precipitation chamber, conveying a resulting mixture of fluid and the fine particles from the precipitation chamber to a collection chamber, the collection chamber having an inlet and an outlet separate from the inlet.
US08609606B2 Polypeptide acting to enhance ischemic diseases
Disclosed is a polypeptide of use in the development of reagents or medicines favourable to application for prevention or treatment of ischemic disorders such as conditions caused by ateriosclerosis. The polypeptide has at least one part containing an amino acid of sequence ID 1, and also enhances expression levels of the amino acid in mammalian blood vessels removed from ischemic conditions by means of blood reperfusion.
US08609602B2 Cleaning solution
Disclosed are cleaning solutions. More particularly, non-toxic solutions of base, water, alcohol and detergent, that effectively and surprisingly eliminate contaminating aliphatic acids in aqueous solutions. When present as a foam or even a contaminating film remaining on various parts and surfaces, aliphatic acid contaminants can be present a large and costly problem in manufacturing operations, cleaning tasks, personal hygiene. The need to remove such contaminants arises in a myriad environments and situations, such as during the manufacture of detergents, pharmaceuticals, consumer products, coring and core analysis, manipulation of oils, fuels, fermentation applications, manufacture of emollients, moisturizers, liquors, foods such as seafood, milk, butter and other dairy products, water processing, paper products, tissue culture, reusable clinical equipment, and the like. Presented are cleaning compositions and methods that effectively eliminate and prevent build up of such dangerous and costly contaminants in aqueous solutions.
US08609599B2 Marine engine lubrication
Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity and a minor amount of one or more phenolic compounds comprising distilled cashew nut shell liquid or hydrogenated distilled cashew nut shell liquid. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.
US08609597B2 Estolide compositions having excellent low temperature properties
A lubricant or process fluid composition having excellent low temperature properties comprises a capped estolide ester, a polyalphaolefin, a synthetic ester and/or polyalkylene glycol, and a pour point depressant. The combination of the three base oils plus the pour point depressant produces a synergistic composition that may have a pour point less than −15° C., preferably less than −35° C., while also having more than 50 percent by weight renewable carbons and being economical and effective in a wide variety of applications.
US08609594B2 Chlorine dioxide precursor and methods of using same
According to one aspect of the invention, a method of converting an oxy halide salt into a halide dioxide in a reaction zone under certain conditions is provided. More specifically, the method includes generating chlorine dioxide from a stable composition comprising an oxy halide salt by introducing said composition to a reducing agent and minimum temperature within the reaction zone. According to another aspect of the invention, a composition for a stable chlorine dioxide precursor comprising an oxy halide salt is provided.
US08609593B2 Extremely low resistance films and methods for modifying and creating same
Operational characteristics of an extremely low resistance (“ELR”) film comprised of an ELR material may be improved by depositing a modifying material onto appropriate surfaces of the ELR film to create a modified ELR film. In some implementations of the invention, the ELR film may be in the form of a “c-film.” In some implementations of the invention, the ELR film may be in the form of an “a-b film,” an “a-film” or a “b-film.” The modified ELR film has improved operational characteristics over the ELR film alone or without the modifying material. Such operational characteristics may include operating in an ELR state at increased temperatures, carrying additional electrical charge, operating with improved magnetic properties, operating with improved mechanic properties or other improved operational characteristics. In some implementations of the invention, the ELR material is a mixed-valence copper-oxide perovskite, such as, but not limited to YBCO. In some implementations of the invention, the modifying material is a conductive material that bonds easily to oxygen, such as, but not limited to, chromium.
US08609589B2 Fungicidal agent combinations
The invention relates to novel fungicidally active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide of the formula and active compounds listed in the disclosure.
US08609587B2 Synergistic herbicidal compositions containing propyzamide and aminopyralid
An herbicidal composition containing (a) propyzamide and (b) aminopyralid provides synergistic control of selected weeds in oilseed rape and in broadleaf, grass and perennial crops.
US08609586B2 Safening composition of 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylate herbicides and cloquintocet-mexyl for cereal crops
Herbicidal injury caused by 6-(trisubstituted phenyl)-4-amino-2-pyridinecarboxylates in wheat and barley is reduced with the use of low rates of cloquintocet.
US08609585B2 Composition and method for controlling plant diseases
The present invention provides a composition for controlling plant diseases comprising, as active ingredients, a compound represented by formula (1) and ethaboxam.
US08609582B2 Thermosensitive recording medium
The present invention presents a thermosensitive recording medium having sufficient water resistance against water or moisture when the thermosensitive recording medium is used outdoors and also having a superior printing run-ability when printing at high speed (sticking resistance), color developing sensitivity, scratching resistance, plasticizer resistance and solvent resistance.The thermosensitive recording medium shows a superior water resistance and also shows a superior printing run-ability when printing at high speed (sticking resistance) etc, by installing a thermosensitive recording layer on a support and a protective layer on the thermosensitive recording layer, wherein the protective layer contains an acrylic resin with a glass transition temperature of higher than 50 degrees C. and lower than or equal to 95 degrees C.
US08609578B2 Exhaust gas purifying catalyst
An exhaust gas purifying catalyst is constituted by: noble metal particles (1); first compounds (2) which support the noble metal particles (1); second compounds (3) different in type from the first compounds (2); and oxides (4) which surround the noble metal particles (1), the first compounds (2) and the second compounds (3). A median diameter of the first compounds (2) and a median diameter of the second compounds (3) satisfy a relationship of a following inequality: median diameter of first compounds
US08609576B2 Catalysts containing tungstate for the synthesis of alkyl mercaptan and method for the production thereof
The invention relates to a catalyst containing alkali tungstate for the synthesis of alkylmercaptanes from alkanols and hydrogen sulphide, in addition to a method for the production of said catalyst, wherein the molar ratio of alkali to tungstan is <2:1.
US08609574B2 In situ olefin polymerization catalyst system
Embodiments in accordance with the present invention encompass methods of forming in situ olefin polymerization catalyst systems, catalysts encompassed by such systems and polymers made using such systems. For such in situ olefin polymerization catalyst systems, a hydrocarbyl magnesium halide is generally contacted with a halohydrocarbyl compound to form a halohydrocarbyl Grignard and such Grignard is generally contacted with a Group 10 metal compound to form an olefin polymerization catalyst which is contacted with one or more olefin monomers to form a polymer therefrom.
US08609573B2 Photocatalytic methods for preparation of electrocatalyst materials
The invention relates to methods of preparing metal particles on a support material, including platinum-containing nanoparticles on a carbon support. Such materials can be used as electrocatalysts, for example as improved electrocatalysts in proton exchange membrane fuel cells (PEM-FCs).
US08609572B2 Basic ionic liquids
Use of ionic liquids as solvents in base-catalysed chemical reactions wherein the ionic liquid is composed of at least one species of cation and at least one species of anion, characterized in that a cation of the ionic liquid comprises a positively charge moiety and a basic moiety, and further wherein such ionic liquids may be used as promoters or catalysts for the chemical reactions.
US08609568B2 Catalyst for oxidative dehydrogenation of propane to propylene
The catalyst for oxidative dehydrogenation of propane to propylene includes vanadium and aluminum incorporated into the framework of a mesoporous support, viz., MCM-41, to form V—Al-MCM-41, and nickel impregnated onto the walls of the mesoporous support. Nickel loading is preferably in the range of 5 to 15% by weight of the catalyst. A process for the production of propylene from propane includes steps of placing the catalyst in a fixed bed reactor, introducing a flow of feedstock in a propane:oxygen:nitrogen ratio of about 6:6:88 by volume, maintaining the reactor at atmospheric pressure and in a temperature range of about 400 to 550° C., collecting the product, and separating propylene from the product. The process achieves propane conversion between about 6 to 22%, and a selectivity for propylene between about 22 and 70%, depending upon percent nickel content and temperature of the reaction.
US08609567B2 OCP catalyst with improved steam tolerance
A catalyst is present for use in an olefin cracking process. The catalyst is a zeolite that has been loaded with an alkaline earth metal. The alkaline earth metal loaded catalyst has an increased steaming tolerance and increases the useful life of the catalyst during the cracking process and the regeneration cycle.
US08609562B2 Plate brick production method and plate brick
Disclosed is a method of producing a plate brick, which comprises: adding an organic binder to a refractory raw material mixture containing aluminum and/or an aluminum alloy; kneading them; forming the kneaded mixture into a shaped body; and burning the shaped body in a nitrogen gas atmosphere at a temperature of 1000 to 1400° C., wherein: when a temperature of a furnace atmosphere is 300° C. or more, the atmosphere is set to a nitrogen gas atmosphere; and when the temperature of the furnace atmosphere is 1000° C. or more, an oxygen gas concentration in the atmosphere is maintained at 100 volume ppm or less, and a sum of a carbon monoxide gas concentration and a carbon dioxide gas concentration is maintained at 1.0 volume % or less. This makes it possible to form a large amount of fine and uniform aluminum nitride in a plate brick to prevent microstructural degradation due to hydration caused by formation of aluminum carbide and suppress oxidation of a carbon bond so as to improve surface-roughening resistance.
US08609561B2 Metal colloid-colored glass ceramic and colorless glass convertible into same
A colorless transparent colloid-former-containing glass that is convertible into a colorless transparent glass ceramic or a metal colloid-colored glass ceramic via respective heat treatments contains a combination of one or more metal colloid formers and one or more redox partners. The metal colloid formers are preferably oxides containing Au, Ag, As, Bi, Nb, Cu, Fe, Pd, Pt, Sb and/or Sn. The redox partners are preferably oxides containing As, Ce, Fe, Mn, Sb, Sn and/or W, with the proviso that the redox partner must be different from the metal colloid former. The glass advantageously contains from 0.97 to 1.9 wt. % SnO2, 0.93 to 3.0 wt. % As2O3, or 1.59 to 6.0 wt. % of Sb2O3 as redox partner.
US08609560B2 Optical glass, preform for precision press molding, optical element, and method for manufacturing optical element
The present invention relates to an optical glass having a refractive index nd of 1.86 or higher and an Abbé number v(nu)d of 28 to 36; a preform for precision press molding and an optical element that are comprised of this glass; and a method for manufacturing the optical element.
US08609558B2 Tackifier composition
A tackifier composition includes a carrier solvent, a resin material, and an inorganic filler. The tackifier composition may be deposited onto at least a portion of a woven fiber structure and then dried to remove the carrier solvent. The dried woven fiber structure may then be formed into a preform.
US08609556B2 Thin film deposition apparatus with an expanding thermal plasma source and method for depositing a thin film using the same
Assembly and method for depositing a thin film including: providing an expanding thermal plasma plume, including at least one chemical component to be deposited; designating a first and a second deposition zone within the plasma plume, such that the first and second deposition zones have a mutually different relative content of the chemical component; providing a substrate, and transporting said substrate through the plasma plume along a substrate transport path having a substrate transport path direction; and providing a mask that is at least partly disposed in the plasma plume and that shields a portion of the substrate transport path from being deposited on, wherein said shielded portion of the substrate transport path extends in the direction of the substrate transport path and bridges at least the first deposition zone, while it starts or terminates in the second deposition zone.
US08609555B2 Increased stability of a complex material stack in a semiconductor device by providing fluorine enriched interfaces
When forming complex metallization systems, a sensitive material, such as a ULK material, may be deposited on a silicon-containing dielectric material, such as an etch stop material, with superior adhesion by performing a surface treatment on the basis of fluorine radicals. Due to the fluorine treatment, silicon-fluorine bonds are generated, which are then broken up upon interacting with the chemically active component during the further deposition process. Consequently, the subsequent material layer is chemically bonded to the underlying material, thereby imparting superior stability to the interface, which in turn may result in superior robustness and reliability of the metallization system upon performing reflowing processes and operating complex packaged semiconductor devices.
US08609550B2 Methods for manufacturing integrated circuit devices having features with reduced edge curvature
A structure, such as an integrated circuit device, is described that includes a line of material with critical dimensions which vary within a distribution substantially less than that of a mask element, such as a patterned resist element, used in etching the line. Techniques are described for processing a line of crystalline phase material which has already been etched using the mask element, in a manner which straightens an etched sidewall surface of the line. The straightened sidewall surface does not carry the sidewall surface variations introduced by photolithographic processes, or other patterning processes, involved in forming the mask element and etching the line.
US08609546B2 Pulsed bias plasma process to control microloading
A method for etching a conductive layer through a mask with wider and narrower features is provided. A steady state etch gas is flowed. A steady state RF power is provided to form a plasma from the etch gas. A pulsed bias voltage is provided during the steady state etch gas flow, wherein the pulsed bias voltage has a frequency between 1 to 10,000 Hz. Wider and narrower features are etched into the conductive layer using the plasma formed from the etch gas.
US08609542B2 Profiling solid state samples
Methods may operate to position a sample within a processing chamber and operate on a surface of the sample. Further activities may include creating a layer of reactive material in proximity with the surface, and exciting a portion of the layer of reactive material in proximity with the surface to form chemical radicals. Additional activities may include removing a portion of the material in proximity to the excited portion of the surface to a predetermined level, and continuing the creating, exciting and removing actions until at least one of a plurality of stop criteria occurs.
US08609541B2 Polishing slurry for metal films and polishing method
Provided are a polishing slurry for metal films and a polishing method which restrain the generation of erosion and seams, and makes the flatness of a surface polished therewith or thereby high. The slurry and the method are a polishing slurry, for metal films, comprising abrasive grains, a methacrylic acid based polymer and water, and a polishing method using the slurry, respectively.
US08609540B2 Reliable packaging and interconnect structures
Methods and apparatus for forming a semiconductor device are provided which may include any number of features. One feature is a method of forming an interconnect structure that results in the interconnect structure having a top surface and portions of the side walls of the interconnect structure covered in a dissimilar material. In some embodiments, the dissimilar material can be a conductive material or a nano-alloy. The interconnect structure can be formed by removing a portion of the interconnect structure, and covering the interconnect structure with the dissimilar material. The interconnect structure can comprise a damascene structure, such as a single or dual damascene structure, or alternatively, can comprise a silicon-through via (TSV) structure.
US08609539B2 Embedded semiconductor device substrate and production method thereof
An embedded semiconductor device substrate having a semiconductor device integrated therein is formed by disposing a semiconductor device in an opening provided on an insulating resin, and sandwiching the semiconductor device and the insulating resin with a front surface wiring layer and a rear surface wiring layer and performing heat pressing. Connection between bumps of the semiconductor device and the front surface wiring layer is made with a connection wiring pattern. The connection wiring pattern is formed by patterning a resist film by direct exposure thereof with a light beam, and then performing etching. Thereby, it becomes possible to absorb a mounting error of a semiconductor device to a printed wiring board and a positional error of electrodes between semiconductor devices accompanying the tendency of reduction of the pitch of a semiconductor device, and to perform electric connection with a wiring pattern securely.
US08609532B2 Magnetically sintered conductive via
The present disclosure relates to the field of fabricating microelectronic packages, wherein microelectronic components of the microelectronic packages may have sintered conductive vias comprising sintered metal and magnetic particles.
US08609528B1 High-density patterning
Methods for patterning high-density features are described herein. Embodiments of the present invention provide a method comprising patterning a first subset of a pattern, the first subset configured to form a plurality of lines over the substrate, and patterning a second subset of the pattern, the second subset configured to form a plurality of islands over the substrate, wherein said patterning the first subset and said patterning the second subset comprise at least two separate patterning operations.
US08609524B2 Method for making semiconductor device comprising replacement gate electrode structures with an enhanced diffusion barrier
In sophisticated semiconductor devices, the integrity of the device level may be enhanced after applying a replacement gate approach by providing an additional diffusion barrier layer, such as a silicon nitride layer, thereby obtaining a similar degree of diffusion blocking capabilities as in semiconductor devices without performing a replacement gate approach.
US08609523B2 Method of making a memory array with surrounding gate access transistors and capacitors with global staggered local bit lines
A memory array with staggered local data/bit lines extending generally in a first direction formed in an upper surface of a substrate and memory cell access transistors extending generally upward and aligned generally atop a corresponding local data/bit line. Selected columns of the memory cell access transistors are sacrificed to define local data/bit access transistors which are interconnected with overlying low resistance global data/bit lines. The global data/bit lines provide selectable low resistance paths between memory cells and sense amplifiers. The sacrificed memory cell access transistors and staggered local data/bit lines provide increased footprints for sense amplifiers to facilitate increased circuit integration.
US08609522B2 Process for producing a conducting electrode
A process for producing a conducting electrode on a substrate, including: depositing a layer made of a dielectric; depositing a protective layer made of the nitride of a metal on the dielectric layer; depositing a functionalization layer made of a material including a chemical species, such that the free enthalpy of formation of the nitride of the species is less, in absolute value, than the free enthalpy of formation of the nitride of the metal of the protective layer over the temperature range between 0° C. and 1200° C.; and annealing the assembly including the protective layer and the funtionalization layer so that the species diffuse from the functionalization layer into the protective layer and the nitrogen atoms migrate from the protective layer into the functionalization layer.
US08609518B2 Re-growing source/drain regions from un-relaxed silicon layer
A method of forming an n-type metal-oxide-semiconductor (NMOS) field-effect transistor (FET) includes forming a silicon germanium layer, and forming a silicon layer over the silicon germanium layer. A gate stack is formed over the silicon layer. The silicon layer is recessed to form a recess adjacent the gate stack. A silicon-containing semiconductor region is epitaxially grown in the recess to form a source/drain stressor, wherein the silicon-containing semiconductor region forms a source/drain region the NMOS FET.
US08609517B2 MOCVD for growing III-V compound semiconductors on silicon substrates
A device includes providing a silicon substrate; annealing the silicon substrate at a first temperature higher than about 900° C.; and lowering a temperature of the silicon substrate from the first temperature to a second temperature. A temperature lowering rate during the step of lowering the temperature is greater than about 1° C./second. A III-V compound semiconductor region is epitaxially grown on a surface of the silicon substrate using metal organic chemical vapor deposition (MOCVD).
US08609515B2 Dicing die bonding film, semiconductor wafer, and semiconductor device
A dicing die bonding film including a bonding layer; and a pressure-sensitive adhesive layer adjoining the bonding layer, the pressure-sensitive adhesive layer having a storage modulus of about 400 to about 600 kPa at 25° C. and a peel strength of about 200 to about 350 mN/25 mm with respect to the bonding layer as measured according to KS-A-01107 standard.
US08609511B2 Semiconductor device manufacturing method, semiconductor device, and camera module
According to one embodiment, an insulation film is formed over the surface, backside, and sides of a first substrate. Next, the insulation film formed over the surface of the first substrate is removed. Then, a joining layer is formed over the surface of the first substrate, from which the insulation film has been removed. Subsequently, the first substrate is bonded to a second substrate via a joining layer.
US08609507B2 Semiconductor device and method of manufacturing the same
A semiconductor device includes gates formed over a semiconductor substrate that are spaced apart from one another and each have a stack structure of a tunnel insulation layer, a floating gate, a dielectric layer, a first conductive layer, and a metal silicide layer, a first insulation layer formed along the sidewalls of the gates and a surface of the semiconductor substrate between the gates and configured to have a height lower than the top of the metal silicide layer; and a second insulation layer formed along surfaces of the first insulation layer and surfaces of the metal silicide layer and configured to cover an upper portion of a space between the gates, wherein an air gap is formed between the gates.
US08609505B2 Method of forming MIM capacitor structure in FEOL
A capacitor structure includes a semiconductor substrate; a first capacitor plate positioned on the semiconductor substrate, the first capacitor plate including a polysilicon structure having a surrounding spacer; a silicide layer formed in a first portion of an upper surface of the first capacitor plate; a capacitor dielectric layer formed over a second portion of the upper surface of the first capacitor plate and extending laterally beyond the spacer to contact the semiconductor substrate; a contact in an interlayer dielectric (ILD), the contact contacting the silicide layer and a first metal layer over the ILD; and a second capacitor plate over the capacitor dielectric layer, wherein a metal-insulator-metal (MIM) capacitor is formed by the first capacitor plate, the capacitor dielectric layer and the second capacitor plate and a metal-insulator-semiconductor (MIS) capacitor is formed by the second capacitor plate, the capacitor dielectric layer and the semiconductor substrate.
US08609502B1 Method of manufacturing semiconductor device including insulated gate bipolar transistor and diode
In a method of manufacturing a semiconductor device, a semiconductor substrate of a first conductivity type having first and second surfaces is prepared. Second conductivity type impurities for forming a collector layer are implanted to the second surface using a mask that has an opening at a portion where the collector layer will be formed. An oxide layer is formed by enhanced-oxidizing the collector layer. First conductivity type impurities for forming a first conductivity type layer are implanted to the second surface using the oxide layer as a mask. A support base is attached to the second surface and a thickness of the semiconductor substrate is reduced from the first surface. An element part including a base region, an emitter region, a plurality of trenches, a gate insulating layer, a gate electrode, and a first electrode is formed on the first surface of the semiconductor substrate.
US08609498B2 Transistor with embedded Si/Ge material having reduced offset and superior uniformity
In sophisticated semiconductor devices, a strain-inducing embedded semiconductor alloy may be provided on the basis of a crystallographically anisotropic etch process and a self-limiting deposition process, wherein transistors which may not require an embedded strain-inducing semiconductor alloy may remain non-masked, thereby providing superior uniformity with respect to overall transistor configuration. Consequently, superior strain conditions may be achieved in one type of transistor, while generally reduced variations in transistor characteristics may be obtained for any type of transistors.
US08609496B2 Method of fabricating semiconductor device comprising a dummy well
Provided are a semiconductor device and a method of fabricating the semiconductor device. The semiconductor device can include first transistors that include a first gate insulating layer having a first thickness and second transistors include a second gate insulating layer having a second thickness less than the first thickness. At least one of the transistors formed on the first or second gate insulating layers is directly over a dummy well.
US08609495B2 Hybrid gate process for fabricating finfet device
Provided is a method of fabricating a semiconductor device that includes forming first and second fins over first and second regions of a substrate, forming first and second gate structures over the first and second fins, the first and second gate structures including first and second poly gates, forming an inter-level dielectric (ILD) over the substrate, performing a chemical mechanical polishing on the ILD to expose the first and second poly gates, forming a mask to protect the first poly gate of the first gate structure, removing the second poly gate thereby forming a first trench, removing the mask, partially removing the first poly gate thereby forming a second trench, forming a work function metal layer partially filling the first and second trenches, forming a fill metal layer filling a remainder of the first and second trenches, and removing the metal layers outside the first and second trenches.
US08609491B2 Method for fabricating semiconductor device with buried bit lines
A method for fabricating a semiconductor device includes etching a substrate to form trenches that separate active regions, forming an insulation layer having an opening to open a portion of a sidewall of each active region, forming a silicon layer pattern to gap-fill a portion of each trench and cover the opening in the insulation layer, forming a metal layer over the silicon layer pattern, and forming a metal silicide layer as buried bit lines, where the metal silicide layer is formed when the metal layer reacts with the silicon layer pattern.
US08609486B1 Methods for fabricating deep trench capacitors
Integrated circuits with transistors and decoupling capacitor structures are provided. A decoupling capacitor structure may include multiple deep trench structures formed in a semiconductor substrate. The deep trench structures may each be lined with high-κ dielectric material. A conductive metal layer for use in controlling threshold voltages associated with n-channel or p-channel devices may be formed over the high-κ dielectric liner. Conductive material such as aluminum may be used to fill the remaining trench cavity. The high-κ dielectric liner may be simultaneously deposited into the deep trench structures and gate regions of the transistors. In one suitable arrangement, the deep trench structures and transistor metal gates for at least a selected type of transistors may be formed in parallel. In another suitable arrangement, the deep trench structures and the transistor metal gates may be formed in separate steps.
US08609483B2 Method of building compensated isolated P-well devices
Electrical device structures constructed in an isolated p-well that is wholly contained within a core n-well. Methods of forming electrical devices within an isolated p-well that is wholly contained within a core n-well using a baseline CMOS process flow.
US08609478B2 Method for manufacturing semiconductor device
It is an object to provide a highly reliable semiconductor device which includes a thin film transistor having stable electric characteristics. It is another object to manufacture a highly reliable semiconductor device at lower cost with high productivity. In a method for manufacturing a semiconductor device which includes a thin film transistor where a semiconductor layer including a channel formation region using an oxide semiconductor layer, a source region, and a drain region are formed using an oxide semiconductor layer, heat treatment for reducing impurities such as moisture (heat treatment for dehydration or dehydrogenation) is performed so as to improve the purity of the oxide semiconductor layer.
US08609477B2 Manufacturing method for array substrate with fringe field switching type thin film transistor liquid crystal display
A manufacturing method for an array substrate with a fringe field switching (FFS) type thin film transistor (TFT) liquid crystal display (LCD) includes the following steps. A pattern of a gate line (1), a gate electrode, a common electrode (6) and a common electrode line (5) is formed by patterning a first transparent conductive film and a first metal film formed successively on a transparent substrate. Contact holes of the gate line in the pad area and a semiconductor pattern are formed through a patterning process after a gate insulator film, and a semiconductor film and a doped semiconductor film are formed successively. A second metal film is deposited and patterned. A second transparent conductive film is deposited and a lift-off process is performed. And then, a pattern of a source electrode, a drain electrode, a TFT channel and a pixel electrode (4) is formed by etching the exposed second metal film and the doped semiconductor film.
US08609474B2 Method of manufacturing semiconductor device
Disclosed are a semiconductor device and a method of manufacturing the same. In the semiconductor device according to an exemplary embodiment of the present disclosure, at the time of forming a source electrode, a drain electrode, a field plate electrode, and a gate electrode on a substrate having a heterojunction structure such as AlGaN/GaN, the field plate electrode made of the same metal as the gate electrode is formed on the side surface of a second support part positioned below a head part of the gate electrode so as to prevent the gate electrode from collapsing and improve high-frequency and high-voltage characteristic of the semiconductor device.
US08609471B2 Packaging an integrated circuit die using compression molding
A structure (46) for holding an integrated circuit (IC) die (50) during packing includes a flexible structurally reinforced silicone adhesive film (22) and a mold frame (44). The mold frame (44) adheres to an adhesive side (38) of the film (22). A method (20) of packaging the IC die (50) includes placing the IC die (50) on the adhesive film (22) with its active surface (52) and bond pads (54) in contact with an adhesive side (38) of the film (22). A molding compound (58) is dispensed over the IC die, and the IC die (50) is encapsulated using compression molding to form a compression molded encapsulant layer (70). IC die (50) is subsequently released from the film (22) as a panel (72) of IC dies (50).
US08609458B2 Method for producing graphene oxide with tunable gap
A method of fabricating a graphene oxide material in which oxidation is confined within the graphene layer and that possesses a desired band gap is provided. The method allows specific band gap values to be developed. Additionally, the use of masks is consistent with the method, so intricate configurations can be achieved. The resulting graphene oxide material is thus completely customizable and can be adapted to a plethora of useful engineering applications.
US08609451B2 Insitu epitaxial deposition of front and back junctions in single crystal silicon solar cells
Fabrication of a single crystal silicon solar cell with an insitu epitaxially deposited very highly doped p-type silicon back surface field obviates the need for the conventional aluminum screen printing step, thus enabling a thinner silicon solar cell because of no aluminum induced bow in the cell. Furthermore, fabrication of a single crystal silicon solar cell with insitu epitaxial p-n junction formation and very highly doped n-type silicon front surface field completely avoids the conventional dopant diffusion step and one screen printing step, thus enabling a cheaper manufacturing process.
US08609448B2 Omnidirectional reflector
A system and method for manufacturing an LED is provided. A preferred embodiment includes a substrate with a distributed Bragg reflector formed over the substrate. A photonic crystal layer is formed over the distributed Bragg reflector to collimate the light that impinges upon the distributed Bragg reflector, thereby increasing the efficiency of the distributed Bragg reflector. A first contact layer, an active layer, and a second contact layer are preferably either formed over the photonic crystal layer or alternatively attached to the photonic crystal layer.
US08609444B2 Manufacturing method of mounting part of semiconductor light emitting element, manufacturing method of light emitting device, and semiconductor light emitting element
A manufacturing method of a mounting part of a semiconductor light emitting element comprising: preparing a semiconductor light emitting element including an electrode which has a surface, and a board which has a surface; forming a plurality of bump material bodies on at least one of the surface of the electrode and the surface of the board by shaping bump material into islands, wherein the bump material is paste in which metal particles are dispersed, a top surface and a bottom surface of the bump material bodies have different areas, and the top surface is practically flat; solidifying the bump material bodies by thermally processing the bump material bodies; and fixing the semiconductor light emitting element and the board through the bumps.
US08609443B2 Semiconductor device manufacturing method
A semiconductor device manufacturing apparatus is provided with a drawing pattern printing part having a print head which injects a conductive solvent, an insulative solvent and an interface treatment solution. The print head is formed in such a way that desired circuit drawing pattern can be printed on a wafer based on information on the drawing pattern from a wafer testing part, information on the wafer from a storage part and coordinate information from a chip coordinate recognition part. In a semiconductor device manufacturing method according to the present invention, a semiconductor device is manufactured by using the semiconductor device manufacturing apparatus in such a manner that desired circuits are formed through printing process. In the semiconductor device, pad electrodes and so on are formed in such a way that trimming process can be conducted by printing circuit drawing patterns.
US08609442B2 Vapor deposition method, vapor deposition device and organic EL display device
A coating film (90) is formed by causing vapor deposition particles (91) discharged from a vapor deposition source opening (61) of a vapor deposition source (60) to pass through a space between a plurality of control plates (81) of a control plate unit (80) and a mask opening (71) of a vapor deposition mask in this order and adhere to a substrate, while the substrate (10) is moved relative to the vapor deposition mask (70) in a state in which the substrate (10) and the vapor deposition mask (70) are spaced apart at a fixed interval. A difference in the amount of thermal expansion between the vapor deposition source and the control plate unit is detected and corrected. It is thereby possible to form, at a desired position on a large-sized substrate, the coating film in which edge blur and variations in the edge blur are suppressed.
US08609440B2 Semiconductor device and method of manufacturing same
A semiconductor device includes a substrate and a ferroelectric capacitor including a lower electrode, a ferroelectric film, and an upper electrode. The upper electrode includes a first layer formed of an oxide whose stoichiometric composition is expressed as AOx1 and whose actual composition is expressed as AOx2; a second layer formed on the first layer and formed of an oxide whose stoichiometric composition is expressed as BOy1 and whose actual composition is expressed as BOy2; and a metal layer formed on the second layer. The second layer is higher in ratio of oxidation than the first layer. The composition parameters x1, x2, y1, and y2 satisfy y2/y1>x2/x1, and the second layer includes an interface layer of the stoichiometric composition formed at an interface with the metal layer. The interface layer is higher in ratio of oxidation than the rest of the second layer.
US08609438B2 Protein-immobilized electrode and method of manufacturing the same, and functional element and method of manufacturing the same
In one example embodiment, a protein-immobilized electrode is stably used for long time. In one example embodiment, a method of manufacturing the protein-immobilized electrode includes immobilizing cytochrome c552 having high stability to a chemically-stable gold electrode while maintaining electron transfer capability of the cytochrome c552. In one example embodiment, a self-assembled monolayer is formed on a gold electrode by using hydrophobic thiol and hydrophilic thiol. By dipping the gold electrode on which the self-assembled monolayer is formed in a cytochrome c552 solution, a protein-immobilized electrode in which a cytochrome c552 is immobilized to the gold electrode with the self-assembled monolayer in between is produced.
US08609437B2 Biomarkers for the diagnosis and treatment of pancreatic cancer
Compositions and methods for use in methods and kits for the detection of an increased risk of pancreatic cancer are provided. Cyst fluid samples isolated from patients that are positive for at least three of the following markers, mucin 1, mucin 2, mucin 5AC, mucin 5B, mucin 6, CEA CAM 1, CEACAM 5, CEACAM 6, CEACAM 7, CEACAM 8, S100-A6, S100-A8, S100-A9 and S100-A11 indicate that such patients are at greater risk for the development of pancreatic cancer when compared to cyst fluid samples isolated from patients lacking these markers.
US08609436B2 Method
The invention provides a method of detecting the presence of anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and detecting the binding or absence of binding of antibodies to said recombinant MHC molecules. This method allows the detection and/or identification of one or more specific MHC particularly HLA allele antibodies.
US08609434B2 Bio-disc reading apparatus and assay method using same
Provided is a bio-disc reading apparatus for reading information including product authentication of a bio-disc and assay site of a bio-disc, and an assay method using same.
US08609429B2 Methods for identifying high fouling hydrocarbon and for mitigating fouling of process equipment
Methods for determining the fouling propensity of a hydrocarbon stream and for reducing fouling are provided. In one method, the fouling propensity of a hydrocarbon stream is determined by obtaining a parameter value indicative of the fouling propensity at no less than two different temperatures, and an activation energy of fouling by the hydrocarbon stream is derived therefrom. In another method, the thus obtained parameter value at no less than two different temperatures and the activation energy are used to select proper heating fluids and operating temperature and to determine whether to add an antifoulant to the hydrocarbon stream to reduce fouling at a given temperature.
US08609428B2 Colorimetric assay for pyrethroid insecticides on solid items
The invention relates to an assay to test for pyrethroids in a sample. The assay is particularly useful for testing material treated with pyrethroids, such as bed netting and the like.
US08609421B2 Single-molecule real-time analysis of protein synthesis
The present invention is generally directed to compositions, methods, and systems for performing single-molecule, real-time analysis of analytical reactions in which protein synthesis is occurring. The ability to analyze such reactions provides an opportunity to study those reactions as well as to potentially identify factors and/or approaches for impacting such reactions, e.g., to either enhance, inhibit, or otherwise affect such reactions including, but not limited to, affecting the reaction rate, processivity, fidelity, duration, and the like.
US08609416B2 Methods and compositions comprising heat shock proteins
Compositions, and uses thereof, which are beneficial for eukaryotic cells in culture, and methods for their use in promoting cell growth, viability and recombinant protein expression. The methods disclosed in the present application are useful, for example, for improving cell viability and in accelerating the rate of cell growth of cells grown in culture. In one aspect, the supplements of the invention are useful for improving or enhancing the yield of the recombinant proteins from the cell cultures.
US08609413B2 Neurons, astrocytes and oligodendrocytes differentiated from a mammalian pluripotent or neural stem cells exposed to a pyridine deriviative
A method of preparing neural precursor cells by exposing pluripotent stem cells or neural stem cells to a differentiation agent. The agent is a pyridine analog, which in preferred embodiments is a phenylethynyl-substituted or phenylazo-substituted pyridine. In other embodiments, a method of enhancing neural precursor cell survival is provided in which the survival is enhanced by exposure to the pyridine analog. In further embodiments, a method of preparing neuronal cells is provided in which pluripotent or neural stem cells exposed to the pyridine analog are then incubated without the pyridine analog, resulting in differentiation into neurons, astrocytes and oligodendrocytes. These methods may be used in toxicological screens, e.g., to evaluate the neurotoxicity of a test compound.
US08609412B2 Mapc generation of lung tissue
The present invention relates to methods of improving function in lung tissue by administering a population of multipotent adult progenitor cells (“MAPCs”) or differentiated progeny thereof.
US08609411B2 Ex vivo expansion of human hematopoietic stem cells
Methods and kits for expanding the number of hematopoietic stem cells are provided. The methods comprise incubating cells in medium comprising isolated IGFBP-2 and an angiopoietin-like protein (Angptl). Expanded HSCs are provided as well as culture media and kits for the expansion of human HSCs in a defined medium. Methods of administering expanded human HSCs to and individual are provided as well as methods of treating an individual by administering certain growth factors and cytokines.
US08609410B2 Method for activation treatment of antigen-presenting cell
Activated antigen-presenting cells that can induce immunocytes including disease antigen-specific CD8+ CTLs and/or γδ T cells efficiently in vivo and/or in vitro, a medical composition comprising the activated antigen-presenting cells, a treatment and prevention method using the activated antigen-presenting cells, and an induction method of immunocytes including disease antigen-specific CTLs and/or γδ T cells induced using the activated antigen-presenting cell, immunocytes induced by the above-noted method, a medical composition comprising the immunocytes, and a treatment and prevention method using the immunocytes are provided. By co-pulsing antigen-presenting cells with bisphosphonate in addition to the pulse with a disease antigen, the ratio of disease antigen-specific CD8+ CTLs and/or γδ T cells and the number of the disease antigen-specific CD8+ CTLs and the γδ T cells can be increased, compared with the case where the co-pulse with bisphosphonate is not carried out.
US08609409B2 Methods and compositions for cell culture platform
The present invention provides a synthetic cell culture platform, comprising: a two dimensional and/or three dimensional surface comprising peptides conjugated to said surface and methods of using the platform for increasing cell adhesion, stable attachment and/or proliferation of cells grown on the platform and for promoting differentiation of neural stem cells into neurons.
US08609404B2 Vaccines containing canine parvovirus genetic variants
Canine parvovirus vaccines and diagnostics and methods for their use are provided. The vaccines are effective against emerging canine parvovirus variants.
US08609403B2 Polynucleotide derived from novel hepatitis C virus strain and use thereof
A polynucleotide encoding the amino acid shown in SEQ ID NO:2 or SEQ ID NO: 5, or encoding an amino acid sequence having not less than 98% identity thereto; preferably a polynucleotide comprising replacement of the amino acid corresponding to glutamic acid at position 1202 of SEQ ID NO:2 (position 177 of SEQ ID NO:5) with glycine, replacement of the amino acid corresponding to glutamic acid at position 1056 (position 31 of SEQ ID NO:5) with valine, and replacement of the amino acid corresponding to alanine at position 2199 (position 1174 of SEQ ID NO:5) with threonine.
US08609401B2 Detection of proteases secreted from a pathogenic microorganisms
A diagnostic test kit for detecting the presence or absence of a protease (e.g., aminopeptidase) within a test sample is provided. The test kit comprises a substrate that is capable of being cleaved in the presence of the protease to release a compound. The kit also comprises a lateral flow device that comprises a chromatographic medium. The chromatographic medium defines a detection zone within which is contained a first reagent (e.g., diazonium ion) that is capable of reacting with the compound to form a second reagent (e.g., aromatic azo compound). The second reagent exhibits a color that is different than the color of the first reagent. The lateral flow device also includes an absorbent material located adjacent to the chromatographic medium, the absorbent material receiving the test sample after flowing through the chromatographic medium.
US08609400B2 Apparatus and method for maintaining and/or restoring viability of organs
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate. The perfusion process can be automatically controlled using a control program.
US08609399B2 Reducing insoluble deposit formation in ethanol production
The present inventors have surprisingly discovered that phytic acid tenaciously precipitates with soluble metals in food or fuel ethanol-processing fluid, producing insoluble organometallic salt deposit or scale on the processing equipment that must be removed in order to facilitate further ethanol processing. The present invention relates to converting phytic acid salts or phytates to inorganic phosphates to improve metal solubility and reduce deposition within processing equipment.
US08609398B1 Selective biodegradation of free fatty acids in fat-containing waste
A process of selectively degrading fatty acids in fat-containing waste materials without significant degradation of triglycerides, thereby converting otherwise economically burdensome waste materials into valuable products, involves contacting a fat-containing waste comprising triglycerides and fatty acids with a bacterial culture comprising Pseudomonas bacteria capable of degrading fatty acids into water and carbon dioxide, and wherein the bacterial culture is substantially free of microorganisms capable of producing extra-cellular lipase in an amount that would cause significant degradation of the triglycerides.
US08609395B2 Agonist and antagonist peptides of carcinoembryonic antigen (CEA)
The invention provides a polypeptide comprising an agonist of a MHC Class I binding native sequence having amino acid substitution(s) and enhanced immunogenicity compared to the native sequence. The invention provides DNA encoding the polypeptide, as well as vectors and cells comprising the DNA and methods comprising the administration of the polypeptide.
US08609394B2 Biotechnological production of chondroitin
Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear chondroitin polysaccharide in a microorganism producing a fructosylated derivative of chondroitin.
US08609393B2 Fluorescent proteins and genes encoding them
Fluorescent proteins comprising the following internal amino acid sequence (SEQ ID NO: 47) Gly Tyr Xaa Xaa Xaa Gln Tyr Leu Pro Xaa Pro 1               5                   10 wherein Xaa in position 3 is Ala or Gly, Xaa in position 4 is Phe, His or Tyr, Xaa in position 5 is His, Tyr or Asn, or Xaa in position 10 is Phe or Tyr are disclosed. Such proteins are e.g. isolated or recombinant fluorescent proteins from a Cephalochordata, such as Branchiostoma floridae or Branchiostoma lanceolatum, or isolated mutants or recombinant proteins that have at least 80% amino acid sequence identity with the fluorescent proteins. Isolated and purified structural genes encoding such fluorescent proteins are also disclosed.
US08609389B2 Milk-clotting protease derived from a microorganism
The present invention provides an improved type protease which comprises an amino acid sequence that is at least 75% identical to SEQ ID NO:3, said improved type protease has at least one mutation selected from the group consisting of: (A) replacement of glutamine corresponding to glutamine at position 265 in SEQ ID NO: 3 with an acidic amino acid; and (B) replacement of glutamine at position 266 in SEQ ID NO: 3 with an acidic amino acid, and wherein said improved type protease has milk-clotting activity.
US08609388B2 Modified family 5 cellulases and uses thereof
The present invention relates to a modified Family 5 cellulase comprising a substitution of an amino acid at position 363 with a non-native alanine, serine or threonine, the position determined from alignment of the modified Family 5 cellulase with amino acids 71-397 of a Trichoderma reesei Cel5A amino acid sequence as set forth in SEQ ID NO:1 and enzyme mixtures comprising same. Additionally provided is a genetic construct comprising a nucleic acid sequence encoding the modified Family 5 cellulase and a genetically modified microbe comprising the genetic construct. The invention also provides a process for producing the modified Family 5 cellulase.
US08609379B2 Process for the production of alcohols from biomass
Alcohols useful as fuel compositions are produced from biomass by pretreating the biomass prior to hydrolysis and fermentation. In the pretreatment, the biomass is contacted with an aqueous solution containing a dilute acid with concentration of up to 10 wt % producing a predigested stream containing an aqueous liquor that contains at least a portion of hemicelluloses and a residual biomass that contains celluloses and lignin; separating at least a portion of the aqueous liquor from the residual biomass providing an aqueous liquor stream and a pre-digested biomass stream; then contacting the pre-digested biomass stream with a cooking liquor containing at least one alkali selected from the group consisting of sodium hydroxide, sodium carbonate, sodium sulfide, potassium hydroxide, potassium carbonate, ammonium hydroxide, and mixtures thereof and water. A process that allows for higher recovery of carbohydrates and thereby increased yields is provided.
US08609375B2 Method for detecting viable cells in a sample by using a virus
A method for detecting viable cells such as bacterial cells, within a sample, said method comprising (i) incubating said sample with a virus which is able to infect said cells under conditions which allow said virus to infect and replicate within any such cells which are viable; and (ii) detecting any nucleic acid obtained by replication of the virus in said cell.
US08609373B2 Fusion protein mixture for inducing human pluripotent stem cell and preparation method there of
The invention provides the protein mixture including the fusion proteins of C-myc, SOX2, KLF4, OCT-4, wherein each protein comprises a protein transduction domain (PTD) and a small ubiquitin-like modifier (SUMO) fused with the said protein. The invention further provides the preparation method of the protein mixture and its use for inducing human pluripotent stem cell.
US08609369B2 Yarrowia peroxisomal 2,4-dienoyl-CoA reductase promoter regions for gene expression in yeast
Promoter regions associated with the Yarrowia lipolytica peroxisomal 2,4-dienoyl-CoA reductase (SPS19) gene are disclosed and have been found to be particularly effective for the expression of heterologous genes in yeast. These promoter regions will be useful for driving high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids.
US08609368B2 Process for purifying vancomycin wet body
Provided is a process for purifying a vancomycin wet body, comprising: dissolving a wet body obtained from a microorganism-fermented solution containing vancomycin into a water soluble solvent to a concentration of about 1 to 40 g/L and carrying out reverse osmosis filtration; and carrying out lyophilization of the filtered vancomycin. The process for purifying a vancomycin wet body provides high-purity vancomycin, while avoiding degradation of stability during a drying step.
US08609364B2 Methods for antimicrobial resistance determination
The present invention relates to methods and systems for determining the antibiotic-resistance status of microorganisms. The invention further provides methods for determining the antibiotic-resistance status of microorganisms in situ within a single system.
US08609361B2 Real time electrophysiological testing of agents of interest for treatment of amyloid-type diseases
This invention corresponds to an in vitro method that employs an electrophysiology technique; in particular, an embodiment of the patch-clamp technique in its perforated type, which will allow us evaluating the neurotoxic capacity of protein structures associated to the generation of neurodegenerative diseases. It addition, it allows evaluating potential pharmacologic capacities of candidate molecules (drugs) in order to prevent, treat, or cure the said diseases. The invention involves the use of peptides that cause neurodegenerative diseases in order to form a spontaneous perforated recording that only occurs with peptides in the patch clamp glass pipette.
US08609357B2 Methods for detecting LP-PLA2 activity and inhibition of LP-PLA2 activity
This invention relates to methods for determining the activity of Lp-PLA2 in at least one sample from an animal. The invention also relates to methods for determining the inhibition of Lp-PLA2 activity in samples from animals that are administered an Lp-PLA2 inhibitor.
US08609355B2 Assays for the detection of microbes
Methods, devices, and kits are provided herein for the accurate and rapid detection of disease causing microbes in a sample by the detection of microbial components of which correlate to the presence of the microbe. Kits include a first binding agent operatively coupled to an immobilized support; and a second binding agent operatively coupled to one or more pH indicating moieties wherein the first and second binding agents bind with sufficient specificity to the microbial component to permit detection of that component which correlates to the presence of the microbe in the sample.
US08609354B2 Method for selecting patients for treatment with an EGFR inhibitor
The present invention relates to cancer diagnostics and therapies and to the detection of alterations in cancer cells that are diagnostic, prognostic or predictive. In particular, the present invention provides a method for detecting and analyzing whether a patient suffering from a cancer is responsive to the treatment with an EGFR inhibitor. In the method, a tissue section from a cancer sample is subjected to assays based on immunohistochemistry and enzymatic metallography.
US08609346B2 Method for diagnosing alzheimer's disease using serum glycoprotein as biomarker
It is an object of the present invention to detect a change in the metabolism of a glycoprotein having an α2,6-sialyl residue, which is contained in blood, so as to provide an agent and a method for diagnosing sporadic Alzheimer's disease. The present invention provides an agent for diagnosing Alzheimer's disease, which comprises lectin used for detecting an α2,6-sialyl residue-containing glycoprotein.
US08609345B2 Diagnosis of diseases and conditions by analysis of histopathologically processed biological samples using liquid tissue preparations
The invention provides methods for diagnosing diseases such as cancer and other conditions using biological samples. Liquid Tissue samples prepared from histopathologically prepared tissue obtained from a subject surprisingly can be used to identify and, optionally, to quantify analytes that are diagnostic of the presence of a disease, condition or syndrome in the subject.
US08609342B2 Reporter gene assay method
The invention provides a reporter gene assay method by which the sex hormone-like activity inherent in a test substance can be accurately assayed excluding the effects caused by a decrease in cell activity (protein expressing capacity). The assay method is a reporter gene assay method using luciferase-expressing cells which comprises further transferring a GFP gene into the luciferase-expressing cells, measuring the luciferase expression level and GFP expression level, and making a judgment about the thus-measured luciferase expression level using the decrease in GFP expression level as an indication of the decrease in cell activity.
US08609340B2 Control nucleic acids for multiple parameters
Methods are provided for the amplification of at least a first and a second target nucleic acid that may be present in at least one fluid sample using an internal control nucleic acid for qualitative and/or quantitative purposes.
US08609338B2 Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms
The invention provides tandem single nucleotide polymorphisms and methods for their use, for example, in diagnosing Down Syndrome.
US08609337B2 Nucleic acid detection and quantification by post-hybridization labeling and universal encoding
The present invention provides, among other things, methods and compositions for encoding a substrate for detecting and quantifying target nucleic acids.
US08609334B2 Biomarkers for painful intervertebral discs and methods of use thereof
The present disclosure provides methods of diagnosing painful intervertebral discs. The present disclosure also provides methods of treating a painful intervertebral disc.
US08609333B2 Detection of methylated DNA and DNA mutations
The present invention relates to various methods of detecting DNA methylation and defected DNA. In one embodiment, the invention provides a nanosensor bound to a probe that is complementary to a DNA methylation sequence.
US08609329B2 FRET-based assay for screening modulators of receptor cycling
Automated FRET imaging of membrane-bound receptor/ligand complexes can discriminate between a clustered organization of ligand/receptor complexes that occurs during the early endocytic stages following internalization and a random distribution characteristic of late stage disassociation of ligand from the receptor. In the case of the low density lipoprotein receptor (LDL-R) and its ligand, LDL, this feature of FRET imaging forms the basis of an assay to monitor the endosomal release of cholesterol into the cell and identify compounds which alter pH in the endosome thereby inhibiting the disassociation of ligand and cholesterol from the receptor, a mechanism that is involved in regulation of plasma/serum cholesterol.
US08609327B2 Forming sub-lithographic patterns using double exposure
Methods are presented of forming sub-lithographic patterns using double exposure. One method may include providing a photoresist layer over a layer to be patterned; exposing the photoresist layer using a first mask having a first opening; developing the photoresist layer to transfer the first opening into the photoresist layer, forming a boundary in the photoresist layer about the transferred first opening that is hardened; exposing the photoresist layer using a second mask having a second opening that overlaps the boundary; and developing the photoresist layer to transfer the second opening into the photoresist layer, leaving the boundary, wherein the boundary has a sub-lithographic dimension.
US08609318B2 Radiation-sensitive resin composition, method for forming resist pattern and polymer
A radiation-sensitive resin composition includes (A) a polymer that includes a structural unit (I) including a group shown by the following formula (i), (B) a photoacid generator, and (C) a polymer that has a fluorine atom content lower than that of the polymer (A), and includes an acid-labile group. The polymer (A) preferably includes a structural unit shown by the following formula (1) as the structural unit (I). It is preferable that X in the formula (1) represent a divalent or trivalent chain-like hydrocarbon group or alicyclic hydrocarbon group.
US08609314B2 Developing agent and method of manufacturing the same
According to one embodiment, a method of manufacturing a color erasable developing agent including preparing a dispersion containing a fine particle containing a leuco dye and a developer, a fine particle containing a color erasing agent, a toner binder resin fine particle and a medium, aggregating the fine particles in the medium, and heat fusing the aggregate to form a toner particle is provided.
US08609312B2 Toner
A toner is provided which has toner particles containing a charging component and containing an aromatic compound represented by the following formula (1): wherein R1 to R3 each independently represent a hydrogen atom, a hydroxyl group, a carboxyl group, an alkyl group having 1 to 18 carbon atom(s) or an alkoxyl group having 1 to 18 carbon atom(s); R4 to R7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group having 1 to 18 carbon atom(s) or an alkoxyl group having 1 to 18 carbon atom(s); R8 represents a hydrogen atom or a methyl group; and m represents an integer of 1 to 3.
US08609308B1 Smart subfield method for E-beam lithography
The present disclosure provides a method of improving a layer to layer overlay error by an electron beam lithography system. The method includes generating a smart boundary of two subfields at the first pattern layer and obeying the smart boundary at all consecutive pattern layers. The same subfield is exposed by the same electron beam writer at all pattern layers. The overlay error caused by the different electron beam at different layer is improved.
US08609306B2 Method for forming circular patterns on a surface
A method for fracturing or mask data preparation for shaped beam charged particle beam lithography is disclosed, in which a square or nearly-square contact or via pattern is input, and a set of charged particle beam shots is determined which will form a circular or nearly-circular pattern on a surface, where the area of the circular or nearly-circular pattern is within a pre-determined tolerance of the area of the input square or nearly-square contact or via pattern. Methods for forming a pattern on a surface and for manufacturing a semiconductor device are also disclosed.
US08609299B2 Fuel cell sealing structure and manufacture method
A fuel cell seal structure includes a GDL which is formed by a porous body and a gasket which is integrally formed with a peripheral edge of a GDL. The GDL includes a rubber impregnation portion and an impregnation stopping portion. The gasket is integrally formed with a gasket body portion having a thickness dimension larger than a thickness dimension of the GDL and an overlap portion overlapping with the GDL in a plane other than a portion impregnated by the GDL. The rubber impregnation portion of the GDL includes an inner portion which is provided between the impregnation stopping portion and an outer portion overlapping with the overlap portion of the gasket in a plane so as not to overlap with the gasket in a plane.
US08609298B2 Form and fill subgasket
A method for manufacturing a subgasket for a fuel cell stack having a pair of plates disposed in a stack includes the step of positioning a membrane between the plates. The membrane includes an inboard portion and a tortuous form portion. The inboard portion abuts a proton exchange membrane of the fuel cell, and the tortuous form portion abuts each of the plates. The tortuous form portion defines at least one cavity between one of the plates and the membrane. A viscous sealant is injected into the cavity. The sealant is cured to form a compliant bead seal on the membrane.
US08609294B2 Method to provide electrical insulation between conductive plates of a hydrogen fuel cell
A subassembly for a fuel cell includes a fuel cell plate having a first side and a second side. Each of the first side and the second side has a flow field disposed between a pair of headers. An insulating spacer abuts the first side of the fuel cell plate and is disposed adjacent a perimeter of the fuel cell plate. A unitized electrode assembly includes a subgasket, a membrane electrode assembly, and a pair of diffusion medium layers. The membrane electrode assembly has an electrolyte membrane sandwiched between a pair of electrodes. The membrane electrode assembly is sandwiched between the pair of diffusion medium layers. The subgasket surrounds, and is coupled to, the membrane electrode assembly. The subgasket abuts the insulating spacer. An elastomeric seal abuts the second side of the fuel cell plate.
US08609279B2 Lithium secondary battery and method for producing same
A rechargeable lithium battery including a negative electrode made by depositing a noncrystalline thin film composed entirely or mainly of silicon on a current collector, a positive electrode and a nonaqueous electrolyte, characterized in that said nonaqueous electrolyte contains carbon dioxide dissolved therein.
US08609274B2 Nested heatsink housing for lithium ion cells
A cell housing includes a first half section having a longitudinal side having a first end and a second end. A first lateral side extends perpendicularly to the longitudinal side from the first end. The first lateral side has a first tongue. A second lateral side extends perpendicularly to the longitudinal side from the second end. The second lateral side has a first groove. A second half section is identical to the first half section. The first and second half sections are coupled to each other such that the first tongue of the first half section is inserted into the first groove of the second half section and the first tongue of the second half section is inserted into the first groove of the first half section, forming a closed perimeter.
US08609269B2 Cylindrical secondary battery including a cap-up
A cylindrical secondary battery including a cap-up in which a surface region of the cap-up that is to be connected to an external device is partially coated with an insulating agent. Due to the structure of the cap-up, an unusual discharge caused due to an unusual contact of the cap-up with an external conductor, or a short between a positive electrode and a negative electrode of the secondary battery may be prevented.
US08609266B2 Battery pack
A battery pack that prevents a short from being generated when an insulation film near coupling holes formed in the conforming cover is broken by the connection tab due to external impacts and penetrates into the wire while or after the connection tab is assembled with the conforming cover through the coupling holes. The battery pack includes battery cells, a connection tab connecting the battery cells to each other in series or parallel, a conforming cover having a wire and coupling holes formed at one side thereof to allow the connection tab to pass therethrough, the conforming cover electrically connected to the connection tab, a protection circuit module electrically connected to the conforming cover and controlling charging and discharging of the battery cells, and a reinforcing member surrounding at least both sides of upper and lower edges among outer peripheral portions of the coupling holes formed in the conforming cover.
US08609263B1 Systems and methods for forming magnetic media with an underlayer
Systems and methods for forming magnetic media with an underlayer are provided. One such method includes providing a non-magnetic substrate, forming a seed layer above the substrate, the seed layer including MgO, forming an underlayer on the seed layer, the underlayer including a material selected from the group consisting of Pd, Pt, W, Fe, V, Cu, and Ag, and forming a magnetic recording layer on the underlayer, the recording layer including FePt oxide.
US08609258B2 Light emitting devices and compositions
A light emitting composition includes a light-emitting iridium-functionalized nanoparticle, such as a compound of formula (I). The compound of formula (I) further comprises at least one host attached to the core. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition is also disclosed. In an embodiment, the light emitting device can emit white light.
US08609254B2 Microcrystalline anodic coatings and related methods therefor
Methods of preparing metal and metal alloys with partially microcrystalline anodic coatings are disclosed. Associated article therefrom are correspondingly disclosed. The partially microcrystalline anodic coatings exhibit steam, superheated steam, alkaline and acidic resistance. Partially microcrystalline anodic coating can be prepared by impregnation of micropores of a metal or metal substrate with metal precursor species, conversion of the metal precursor species into metal hydroxides, thermal treatment to dry out moisture and to promote phase transformation of the metal hydroxide product into metal oxides solids and bonding with metastable metal oxide substance in the pore structure of the metal or metal alloy substrate, and hydrothermal sealing to create sealed partially microcrystalline anodic coating.
US08609249B2 Thin wall expandable polymer tubes having improved axial and radial strength, and a method of manufacturing thereof
A method for making a thin walled ePTFE tube having improved axial and radial strength includes the steps of: providing an unsintered or partially sintered ePTFE membrane; wrapping the ePTFE membrane around a mandrel or form tool to form an ePTFE tube; matting the ePTFE tube; immediately thereafter, sintering the matted ePTFE tube; removing the sintered ePTFE tube from the mandrel or form tool; stretching the sintered ePTFE tube in the axial direction; stretching the ePTFE tube in the radial direction over a second mandrel that is greater in diameter than the reduced axially stretched diameter, but less than the first mandrel diameter; overwrapping the second mandrel with a second ePTFE membrane; matting the ePTFE tube; immediately thereafter, sintering the matted ePTFE tube; and removing the sintered ePTFE tube from the second mandrel or form tool.
US08609247B2 Capped particles comprising multi-block copolymers for use in lubricants
The present invention relates to additives for use in lubricant compositions to processes for producing the additives, and to the use of the additives in lubricants and in systems that are lubricated. More specifically, the additive includes a capped particle comprising: (i) one or more inorganic core particles; and (ii) one or more multi-block copolymers attached to the inorganic particles. The multi-block copolymer includes at least one nonpolar polymer block interposed between two polar polymer blocks. One polar polymer block is attached to the core particle, and at least a portion of the another polar polymer block is not directly attached to the core particle. When used in a lubricant to lubricate a metallic surface of a workpiece, the capped particle preferably adheres to the metallic surface of the workpiece.
US08609246B2 Electroconductive fine particles, anisotropic electroconductive material, and electroconductive connection structure
A conductive fine particle, which is used for conductive connection between fine electrodes and tends not to give rise to a crack in the solder layer or disconnection caused by breakage in the connection interface between an electrode and the conductive fine particle even with a drop impact and the like, and tends not to have fatigue even after repetitive heating and cooling; an anisotropic conductive material obtained by using the conductive fine particle; and a conductive connection structure.
US08609244B2 Engineered low-density heterogeneous microparticles and methods and formulations for producing the microparticles
A low density material and a method for preparing a low-density material and precursor for forming a low-density material are provided. An aqueous mixture of inorganic primary component and a blowing agent is formed, the mixture is dried and optionally ground to form an expandable precursor. Such a precursor is then fired with activation of the blowing agent being controlled such that it is activated within a predetermined optimal temperature range. The firing conditions are also controlled to provide a low density sphere containing a heterogeneous sphere wall structure comprising a combination of amorphous glass and a crystalline phase or gas phase or both.
US08609238B2 Method and material for a thermally crosslinkable random copolymer
A structure that comprises a substrate; a cross-linked random free radical copolymer on the substrate; and a self-assembled patterned diblock copolymer film on the random copolymer; wherein the random copolymer is energy neutral with respect to each block of the diblock copolymer film. A method of making the structure is provided.
US08609237B2 Composite materials and methods of making the same
The present invention provides composite materials that contain formaldehyde-free aqueous binder compositions comprising defatted soy flour of no greater than 43 micron mesh particle size and polymer particles of at least one emulsion (co)polymer. Preferably, the defatted soy flour is present as an aqueous dispersion, or is in denatured form. Also provided are methods of making and using composite materials containing the formaldehyde-free binder compositions.
US08609232B2 Low permeability rubber laminate and pneumatic tire using the same
A low permeability rubber laminate having an excellent bondability, air pressure retaining property and durability and containing (A) at least one low permeability resin layer having an average thickness d of 0.05 μm
US08609231B2 Composite laminates and uses thereof
The present invention generally relates to composite laminates and uses thereof in articles in need of protection from mechanical damage and water or oxygen based degradation.
US08609225B2 Ethylene-unsaturated ester copolymer film for forming laminate
The object of the present invention to provide an ethylene-unsaturated ester copolymer film used for forming a laminate, which is provided with emboss having effect on prevention on blocking during storage of the film, and which has good tackiness that is required for alignment in a laminating step. A film 40 for forming a laminate, which is formed from a composition comprising an ethylene-unsaturated ester copolymer and has emboss only on one surface 41 of the film, wherein a surface 42 opposite to the surface having emboss is provided with a fine asperity 43, the surface 42 provided with the fine asperity 43 having a surface roughness profile with a mean spacing between peaks (Sm) of 600 to 1600 μm and an arithmetical mean roughness (Ra) of 1.2 to 2.2 μm.
US08609223B2 Interfolded napkins and method for interfolding napkins
A rectangular stack of interfolded rectangular napkins including a plurality of napkins, each napkin in the stack comprising a first fold in a first direction, and a second fold in a second direction perpendicular to the first direction and bisecting the first fold and the napkin in the second direction, the intersecting first and second folds dividing the napkin into four panels with a pair of adjacent panels located on each side of the second fold, wherein each of the napkins within the stack includes at least one pair of panels arranged in the stack at a level between two pairs of adjacent panels of another of the absorbent napkins within the stack.
US08609214B1 Elastomeric film
A combination handheld device and anti-slip film is produced by combining a thin, dimensionally stable plastic film having a smooth surface finish with a silicone elastomer having a low durometer and a textured and polished surface finish. The film includes adhesive means for adhering the film to objects such as a handheld device.
US08609204B2 Apparatus and method for solid freeform fabrication
A Solid Freeform Fabrication system, apparatus and method is provided, that includes a movable fabrication tray adapted to hold an object being fabricated; a depositing surface to hold deposited materials, and ink jet printing heads to selectively deposit a plurality of building materials on the depositing surface; wherein the deposited materials are merged to the object being fabricated, when said fabrication tray moves said object being fabricated to be in contact with said deposited materials.
US08609203B2 Method and apparatus for plasma surface treatment of moving substrate
A method and apparatus for treatment of a substrate surface using an atmospheric pressure plasma is disclosed. The method comprises providing an atmospheric pressure plasma in a treatment space between a first electrode and a second electrode, providing a substrate in contact with the first electrode in the treatment space, and applying a plasma generating power to the first and second electrodes. The first electrode has a predefined structure of insulating areas and conductive areas for plasma treatment of surface areas of the substrate corresponding to the areas in contact with the conductive areas of the first electrode.
US08609199B2 Carbon nanotube growing process, and carbon nanotube bundle formed substrate
In the growth of carbon nanotubes, the aggregation of catalytic fine particles therefor is a problem. In order to realize the growth of carbon nanotubes into a high density, the carbon nanotube growing process includes a first plasma treatment step of treating a surface having catalytic fine particles with a plasma species generated from a gas which contains at least hydrogen or a rare gas without carbon element, a second plasma treatment step of forming a carbon layer on the surface of the catalytic fine particles by a plasma generated from a gas which contains at least a hydrocarbon after the first plasma treatment step, and a carbon nanotube growing step of growing carbon nanotubes by use of a plasma generated from a gas which contains at least a hydrocarbon after the second plasma treatment step.
US08609197B1 Preparing glass containers for electrostatic coating
A glass container and related methods of manufacturing and coating glass containers. The container includes a hot end coating that is deposited on an exterior surface and that includes a metal oxide, and a dopant to reduce electrical resistivity of the exterior surface of the container. The container also includes an organic coating electrostatically applied to the exterior surface of the container. Preferably, the organic coating is applied at an ambient temperature and without having to use grounding pins, without having to heat the container, and without having to apply an additional conductive coating layer.
US08609192B2 Method and device for controlling oxidizing-reducing of the surface of a steel strip running continuously through a radiant tubes furnace for its galvanizing
A method for guaranteeing the oxidation of a strip designed to prevent the selective oxidation of alloy elements of the steel in a continuous steel strip galvanizing annealing furnace having a pre-heating section and a hold section and provided only with radiant tubes. The oxidation of the strip is designed to prevent the selective oxidation of elements of the steel alloy. The novel method includes the following steps: installation of at least one modified tube capable of injection an oxidizing medium at least one point in the oven heating section and/or at least one point in the hold section and injection of the oxidizing medium by means of the modified tube(s), the oxidizing medium having a composition such that in the conditions of the temperature of the oxidizing medium and the steel strip and as a function of the chemical composition of the strip said medium has a dew point which guarantees an in-depth oxidation of the alloy elements of the steel strip.
US08609187B1 Method of producing an oxide dispersion strengthened coating and micro-channels
The disclosure provides a method for the production of composite particles utilizing a mechano chemical bonding process following by high energy ball milling on a powder mixture comprised of coating particles, first host particles, and second host particles. The composite particles formed have a grain size of less than one micron with grains generally characterized by a uniformly dispersed coating material and a mix of first material and second material intermetallics. The method disclosed is particularly useful for the fabrication of oxide dispersion strengthened coatings, for example using a powder mixture comprised of Y2O3, Cr, Ni, and Al. This particular powder mixture may be subjected to the MCB process for a period generally less than one hour following by high energy ball milling for a period as short as 2 hours. After application by cold spraying, the composite particles may be heat treated to generate an oxide-dispersion strengthened coating.
US08609186B2 Method for manufacturing coating film
The presently disclosed subject matter provides a method for manufacturing a coating film whereby a problem of planarity in a plastic film wound up into a roll form can be eliminated and the coating film can be formed uniformly and precisely. There is therefore provided a method for manufacturing a coating film in which a plastic film wound into a roll form is wound off to be allowed to run and is fed while winding the film around a heat roller so as to eliminate deformations in the plastic film, and then a coating liquid is applied onto the plastic film, wherein in a position where wrinkles begin to form in the plastic film due to heating by the heat roller, the plastic film is pneumatically pressed by air jetted from an air nozzle at a pressure equal to or higher than a pressure at which the wrinkles disappear.
US08609182B2 Solution containment during buffer layer deposition
Improved methods and apparatus for forming thin-film layers of chalcogenide on a substrate web. Solutions containing the reactants for the chalcogenide layer may be contained substantially to the front surface of the web, controlling the boundaries of the reaction and avoiding undesired deposition of chalcogenide upon the back side of the web.
US08609178B2 Substrates for spatially selective micron and nanometer scale deposition and combinatorial modification and fabrication
A substrate (1) for spatially selective micron and nanometer scale deposition and/or reaction, which has a support (3), a conductive layer (5) on the support, a dielectric layer (7) to hold an electrostatic charge pattern such as a photoconductive layer of a material which dissipates an electric charge upon receiving incident radiation thereon, and a chemically functional layer (9), such that electrostatic charge patterns may be formed in a predetermined manner upon the substrate to influence the movement of charged droplets in an emulsion (15) on the substrate. The chemically functional layer either provides a surface for chemical functionalization of the substrate or prevents access or reaction to the dielectric or photoconductive layer.
US08609177B2 Production of canola protein product without heat treatment (“C200CaC”)
The supernatant from the deposition of canola protein micellar mass is processed to provide a canola protein product having a protein content of about 60 to less than about 90 wt % (N×6.25) protein on a dry weight basis and which is soluble in an aqueous acidic environment.
US08609176B2 Food composition
A food composition is provided useful for decreasing the amount of sodium while maintaining a high perceived saltiness of the food composition. The food composition comprises a particulate phase and a soluble phase and a selective sodium distribution between the phases whereby the amount of sodium in the particulate phase is at least 4 wt %, more preferably at least 10 wt %, more preferably at least 15 wt % and most preferably at least 20 wt %, and preferably at most 99.99 wt %, more preferably at most 99 wt %, more preferably at most 90 wt %, most preferably at most 70 wt % by weight of the total amount of sodium in the particulate and soluble phase.
US08609175B2 Method of reducing the saturated fatty acid content of milk fat
The present invention is related to a method for reducing the saturated fatty acid content of milk fat. The milk fat is subjected to fractional crystallization to recover an olein fraction. Then the olein fraction is subjected to short path distillation to obtain a residual milk fat fraction that has not been evaporated and has a reduced saturated fatty acid content.
US08609173B2 Compositions comprising sweetness enhancers and methods of making them
The present invention provides solid and liquid compositions comprising 5-(neopentyloxy)-1H-benzo[c][1,2,6]thiadiazin-4-amino-2,2-dioxide or 3-(4-amino-2,2-dioxide-1H-benzo[c][1,2,6]thiadiazin-5-yloxy)-2′,2′-dimethyl-N-propylpropanamide, and methods of making the compositions by spray drying and spin melting. The present invention also provides ingestible compositions comprising compositions of the present invention and methods of making such foods.
US08609170B2 Method for beverage formation with automated water delivery to heating tank
A method and apparatus for forming a beverage using a beverage formation device. Opening of a brew chamber may automatically enable the provision of beverage precursor liquid from a reservoir to a heating tank that is used (heated or not) to form a beverage. For example, opening of the brew chamber may cause a valve to be opened or otherwise permit flow of beverage precursor liquid from the reservoir to the heating tank. The valve may open simultaneously and automatically with a brew chamber lid, and may close when the brew chamber lid is closed.
US08609169B2 Methods for preserving fresh produce
Methods of preserving fresh produce with a produce preservative, particularly cut fresh produce, are provided. The method comprises: providing a solution of produce preservative comprising: water; a preservative cation which is selected from the group consisting of a strontium ion, lithium ion, barium ion, aluminum ion, copper ion, ammonium ion, iron ion, manganese ion, potassium ion, or mixtures thereof; and ascorbate ions, or erythorbate ions; wherein the ascorbate ions or erythorbate ions and the preservative cation are present in an ion ratio of preferably from 0.2:1 to 8:1, more preferably 0.75:1 to 8:1, even more preferably from 1:1 to 4:1, yet more preferably 1.5:1 to 3:1; most preferably 1.1:1 to 2.5:1; and, applying said produce preservative to the produce. The invention also relates to fresh produce preserved with the produce preservatives.
US08609168B2 Food cooking control method and device
The invention relates to a food cooking control method and device. The method includes the following steps in which: at least one temperature detection device is inserted into a food; a final equilibrium temperature is defined; the detection device is positioned inside the food in a pre-determined detection zone so that a temperature (TC) can be obtained at all times during cooking; the TC temperature data obtained are processed using the detection device; the temperature of the surface through which the food receives heat (TP) is determined and processed and the variation in temperature TC is evaluated at least to the first derivative. The device includes a detection device intended to be inserted into the food, a device for determining the thickness of the food and a device for inserting the detection device into the food to a pre-determined depth.
US08609163B2 Herbal formulation advocated for the prevention and management of coronary heart disease
According to this invention there a novel herbal formulation for the prevention and management of coronary heart disease and associated CHD risk factors, comprising, preparing a hydromethanolic extract of at least two plants selected from of Withania somnifera, Costus speciosus, Hippophae rhamnoides and Terminalia arjuna at 60-80° C., maintaining the pH of the solution between 7-10, separating the active compounds chromatographically, subjecting the active compounds to the step of molecular characterization.
US08609158B2 Diane's manna
This is a potent drug with narcotic benefits made from distinctly and uniquely combined and processed interchangeable seed and seed derivatives that are so potent that it removes or alleviates depression, mood disorders, Attention Disorder symptoms, thought disorder, mental illness, pain, right lip retardation symptoms, physical problems, Lymph Node cancer and many other illness symptoms. It removes bumps in the neck within a week or two. It is interchangeable in most aspects. It can be combined and processed with Pharmaceuticals and medicines to create new drugs. These Pharmaceuticals are now long lasting. I prefer the daily dose, but this drug can last months. It is extremely strong or potent and can be made weak to make your little Attention deficit child normal. It is an incredible mood stabilizer and reduces psychosis. Use it for cancer patient and for people with pain issues. It works.
US08609156B2 Compositions and methods of treatment that include plant extracts
The present invention provides for a pharmaceutical composition that provides for the symptomatic relief to an animal (e.g., mammal, such as a human) afflicted with inflammation. The pharmaceutical composition includes a pharmaceutically acceptable carrier and at least two of: (a) sunflower extract, (b) rhubarb root extract, (c) milk thistle extract, (d) dandelion extract, (e) feverfew extract, and (f) ginger extract. The present invention also provides for a method for providing symptomatic relief to a human afflicted with inflammation. The method includes administering to a patient in need of such symptomatic relief an effective amount of the pharmaceutical composition described herein, for a period of time sufficient to provide symptomatic relief to the human.
US08609148B2 Methods of therapeutic treatment of eyes
Provided are electrokinetically-altered aqueous fluids (e.g., gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating an irritation, infection or inflammatory eye condition, comprising administering to, by contacting the eye of a subject in need thereof a therapeutically effective amount of an electrokinetically-altered aqueous fluid. The electrokinetically-altered fluids or therapeutic compositions and methods include electrokinetically-altered ioinic aqueous fluids optionally in combination with other therapeutic agents. Other embodiments include particular routes of administration or formulations for the electrokinetically-altered fluids (e.g., electrokinetically-altered gas-enriched fluids) and therapeutic compositions for use in treating eye conditions. Certain embodiments relate to cosmetic and/or therapeutic fluids and/or methods of treatment utilizing the fluids to treat a cosmetic and/or therapeutic symptom related to eye conditions and/or diseases.
US08609144B2 Sustained release intraocular implants and methods for preventing retinal dysfunction
Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and/or to lower intraocular pressure.
US08609143B2 Morphine polymer release system
A pharmaceutical composition for controlled release of an active substance is provided. The active substance is released into an aqueous medium by erosion of at least one surface of the composition. The composition comprises i) a matrix comprising a) polymer or a mixture of polymers, b) an active substance and, optionally, c) one or more pharmaceutically acceptable excipients, and ii) a coating.
US08609140B2 Calcium carbonate granulation
Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08609138B2 ω3 fatty acid compound preparation
Provided is a compound preparation including at least one selected from the group consisting of ω3 polyunsaturated fatty acids and pharmaceutically acceptable salts and esters thereof and at least one selected from the group consisting of statin compounds and pharmaceutically acceptable salts thereof. The compound preparation is in a form of a soft capsule having a capsule coating with a pH of 7.0 to 9.5. The compound preparation suppresses the decomposition of the statin compounds and/or the modification/insolubilization of the capsule coating. A medical use for the compound preparation, a method of manufacturing the compound preparation and a method of using the compound preparation are also provided.
US08609137B2 Soft capsule of butylphthalide and a process for preparing the same
The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0˜10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2˜0.4:0.8˜1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavor of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.
US08609134B2 Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same
Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin receptor agonist to an individual in need thereof, are provided. Also provided are transdermal formulations of indole serotonin receptor agonists that find use in practicing the subject methods.
US08609130B2 Method for activating hemostatic systems by applying a hemostatic textile
The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.
US08609128B2 Cyanoacrylate-based liquid microbial sealant drape
The invention relates to methods of using compositions for forming microbial sealant drapes. In particular, the invention relates to the use of compositions of combinations of cyanoacrylates for the in situ formation of drapes that can be used in surgery to protect patients from surgical site infections.
US08609124B2 System and methods of maintaining space for augmentation of the alveolar ridge
An implantable screw for maintaining space during bone grafting procedures is provided, where the screw has a highly-polished contoured head having a region adapted to support soft tissue, a threaded shaft and a tip adapted to penetrate bone tissue. Also provided, a device combining multiple implantable screws in series in order to increase the available space to grow new bone and a method for implanting the implantable screw. The implantable screws provided may be used in conjunction with bone graft materials and are removable once a desired amount of new bone is generated.
US08609123B2 Derivatized poly(ester amide) as a biobeneficial coating
A derivatized poly(ester amide) (D-PEA) and coatings and medical devices formed therefrom are provided. The coatings and medical devices may optionally include a biobeneficial material and/or a biocompatible polymer and/or a bioactive agent. The medical devices can be implanted in a patient to treat, prevent, or ameliorate a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
US08609120B2 Use and generation of ozone as a disinfectant of dairy animal tissues, dairy equipment, and infrastructure
An ozone delivery system, method, and apparatus are disclosed. Ozonated water can be used to disinfect and clean various surfaces, equipment, and animals in a dairy setting. Animals can be disinfected and protected from disease through the use of wash-pen and sprayer injections, and other footbath products. Ozone can be educted into a drop hose and a pre-dip line at periodic intervals and into a foot bath to provide refreshed ozonated water. The ozone delivery system and method sterilizes all equipment and floor surfaces without damaging diary equipment components. The system can incorporate computer-controlled options such as maintaining off gas levels, maintaining cleaning and disinfecting records, monitoring ozonated water levels, monitoring concentrations of ozone in said ozonated water, controlling entry and exit gates, controlling a drainage system, and monitoring and educting ozone in a foot bath and wash pen.
US08609112B2 Botulinum toxin treatments of depression
Methods for preventing or treating depression including a depression mediated by the thalamus. Depression, including a thalamically mediated depression, can be treated by peripheral administration of a botulinum toxin to or to the vicinity of a trigeminal sensory nerve, thereby preventing or treating the depression.
US08609111B2 Antibodies against clostridium difficile toxins and uses thereof
Antibodies that specifically bind to toxins of C. difficile, antigen binding portions thereof, and methods of making and using the antibodies and antigen binding portions thereof are provided herein.
US08609110B2 Citrobacter freundii antibacterial agents and their use
Provided herein are methods for treating planktonic bacteria or a biofilm. The methods include contacting the planktonic bacteria or biofilm with an effective amount of an isolated Citrobacter freundii colicin A polypeptide, wherein the polypeptide has an antibacterial activity against the planktonic bacteria or the biofilm. Methods are also provided herein for treating a subject that has a bacterial infection, for example caused by a biofilm. The methods can be used to treat a biofilm on a living or non-living surface. Also provided herein are Citrobacter freundii colicin A polypeptides that have an antibacterial activity against planktonic bacteria or surface attached bacteria, and nucleic acid sequences encoding the polypeptides. Medical devices comprising a surface having an antimicrobial effective amount of a Citrobacter freundii colicin A polypeptide, or a nucleic acid molecule encoding the polypeptide, are also disclosed.
US08609109B2 HIV vaccine formulations
Provided herein are HIV vaccines comprising HIV polypeptide-encoding DNA adsorbed to PLG and/or HIV proteins. Also provided are methods of using these vaccines to generate immune responses in a subject.
US08609108B2 Gamma-glutamyl transpeptidase attenuated Francisella
The present invention relates to a mutated Francisella bacterium, wherein the ggt gene is silenced or deleted; pharmaceutical compositions comprising the same, in particular, vaccine compositions, and use of the bacterium and compositions for treatment and/or prophylaxis, and in particular, the treatment or prophylaxis of tularemia.
US08609107B2 Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
The invention provides methods of treating subject with polypeptides having at least 80% identity to SEQ ID NO: 5326. The methods stimulate an immune response in the subject and provide methods for prevention and treatment of pathological conditions resulting from bacterial infection.
US08609104B2 Treatment of B-cell cancers with anti-CD70 antibody-drug conjugates
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of a CD70-expressing cancer, comprising administering to a subject the disclosed pharmaceutical compositions.
US08609100B2 Method for inhibiting dendritic cell immunoreceptor (DCIR)-mediated human immunodeficiency virus infection comprising administering anti-DCIR antibodies
A cell surface molecule designated DCIR (for dendritic cells ImmunoReceptor), a member of a recently described family of DC-expressing C-type lectin receptors, has been shown to participate to the capture of human immunodeficiency virus (HIV) and promote infection in trans and in cis of autologous CD4(+) T cells from human immature monocyte-derived DC. The contribution of DCIR to these processes was revealed using DCIR-specific siRNAs and a polyclonal antibody specific for the carbohydrate recognition domain of DCIR. Therapeutic agents for HIV infection are therefore provided herein. These therapeutic agents are useful for impairing the interaction between DCIR and HIV and as such may be useful for treatment or prevention of HIV infection. Also provided are assays for identifying additional therapeutics agents for treatment or prevention HIV infection.
US08609096B2 Monoclonal antibodies against PCBP-1 antigens, and uses therefor
The present invention provides and includes monoclonal antibodies (MoAbs or mAbs) specific or preferentially selective for PCBP-1 antigens, hybridoma lines that secrete these PCBP-1 antibodies or antibody fragments, and the use of such antibodies and antibody fragments to detect PCBP-1 antigens, particularly those expressed by cancer cells. The present invention also includes antibodies that are specific for or show preferential binding to a soluble form of PCBP-1. The present invention further includes chimeric and humanized antibodies, processes for producing monoclonal, chimeric, and humanized antibodies using recombinant DNA technology, and their therapeutic uses, particularly in the treatment of cancer. The present invention further includes methods and kits for the immunodetection and immunotherapy of cells for samples which express PCBP-1 antigens.
US08609095B2 Anti-HER2 antibodies and compositions
The present invention relates to novel therapeutic antibodies directed against HER2 (ErbB2), as well as recombinant polyclonal anti-HER2 antibody compositions comprising at least two of said recombinant anti-HER2 antibodies, and use of the antibodies and antibody compositions for treatment of cancer.
US08609089B2 Compositions of PD-1 antagonists and methods of use
Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such as cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.
US08609087B2 Compounds and methods for identifying compounds which inhibit a new class of aspartyl proteases
Compounds and methods for designing and identifying compounds which inhibit TFPP-like aspartyl protease enzymes by targeting the aspartic acid residues of the active site or mimicking peptides corresponding to the region surrounding the substrate's cleavage site are provided. Agents identified as inhibitors of TFPP-like aspartyl proteases such as type 4 prepilin peptidases are expected to be useful as anti-bacterial agents and in inhibiting development of drug resistant strains of bacteria.
US08609085B2 Use of gingival fibroblasts for vascular cell therapy
The invention relates to the use of gingival fibroblasts for obtaining a cellular composition for treating arterial-remodelling pathology, for example an aneurysm, post-cryoplasty stenosis and restenosis, an aortic dissection or atherosclerosis.
US08609082B2 Administering bone marrow progenitor cells or myoblasts followed by application of an electrical current for cardiac repair, increasing blood supply or enhancing angiogenesis
A method is provided including selecting a patient suffering from a condition, administering cells to the patient selected from the group consisting of: progenitor cells and genetically-modified cells, applying an electrical current to a site of the patient in a vicinity of nervous tissue, and configuring the current to stimulate the nervous tissue. Other embodiments are also described.
US08609079B2 Longwearing, transfer resistant cosmetic compositions having a unique creamy texture and feel
The present invention is directed to a long wearing, transfer resistant cosmetic composition which is waterproof, comfortable and has a unique creamy texture and feel containing: (a) a reaction product of (i) at least one polyamine and (ii) at least one oil soluble high carbon polar modified polymer; (b) water; (c) at least one volatile solvent capable of solubilizing the polar modified polymer; (d) optionally at least one non-volatile solvent; and (e) optionally, at least one colorant.
US08609078B2 Composition for shaping keratin fibers containing starches modified with propylene oxide
Cosmetic agents for temporary deformation of keratinic fibers containing, in a cosmetic carrier, at least one starch modified with propylene oxide and having an average molecular weight (weight average) of from 50 to 2500 kDa, the agents enabling a hairstyle with strong hold and high flexibility. Starches modified with propylene oxide are based on renewable raw materials. In this way, effective styling products for hair are provided without having to use raw materials based on fossil fuels.
US08609075B2 Heparanase activity inhibitor
A heparanase activity inhibitor comprising, as an active ingredient, a cyclic carboxamide derivative represented by formula (I): wherein n is an integer of 1 to 3, R1 is hydrogen or a C1-6 hydrocarbon group optionally substituted with hydroxyl, X is —CH2— or a group represented by —N(R2)—, and R2 is hydrogen or a C1-6 hydrocarbon group optionally substituted with hydroxyl, or a salt thereof.
US08609060B1 Method of producing carbon coated nano- and micron-scale particles
A method of making carbon-coated nano- or micron-scale particles comprising entraining particles in an aerosol gas, providing a carbon-containing gas, providing a plasma gas, mixing the aerosol gas, the carbon-containing gas, and the plasma gas proximate a torch, bombarding the mixed gases with microwaves, and collecting resulting carbon-coated nano- or micron-scale particles.
US08609056B2 Iron(III) orthophosphate for Li ion accumulators
Iron(III) orthophosphate of the general formula FePO4×nH2O (n≦2.5), prepared by a process in which iron(II)-, iron(III)- or mixed iron(II, III) compounds selected from among hydroxides, oxides, oxidehydroxides, oxide hydrates, carbonates and hydroxidecarbonates are reacted with phosphoric acid having a concentration in the range from 5% to 50%, any iron(II) present after the reaction is converted into iron(III) by addition of an oxidant and solid iron(III) orthophosphate is separated off from the reaction mixture.
US08609055B2 Method of producing fluoroapatite, fluoroapatite, and adsorption apparatus
A method of producing fluoroapatite by using a calcium-based compound containing calcium, hydrogen fluoride and phosphoric acid is provided. The method can be produced fluoroapatite having improved acid resistance by reducing an amount of an impurity derived from a raw material to a low or very low level, and ability capable of separating a large amount of a protein due to a large specific surface area thereof. Further, fluoroapatite having high acid resistance and a large specific surface area is also provided. Furthermore, an adsorption apparatus using such fluoroapatite is also provided.
US08609054B2 Hydrogen production from borohydrides and glycerol
A method of forming hydrogen gas comprises the steps of providing a reactor and providing a hydrogen-generating composition to the reactor. The hydrogen-generating composition consists essentially of a borohydride component and a glycerol component. The borohydride, e.g. sodium borohydride, and glycerol components are present in a generally three (3) to four (4) stoichiometric ratio, prior to reaction. The borohydride component has hydrogen atoms and the glycerol component has hydroxyl groups with hydrogen atoms. The method further comprises the step of reacting the borohydride component with the glycerol component thereby converting substantially all of the hydrogen atoms present in the borohydride component and substantially all of the hydrogen atoms present in the hydroxyl groups of the glycerol component to form the hydrogen gas. The reaction between the borohydride component and the glycerol component is an alcoholysis reaction. Reactors and reaction systems employing the method of the present invention are also described.
US08609053B2 Process for preparing of nanowires of metal oxides with dopants in lower valence state
The present invention provides a process for the preparation of nanowires of metal oxides with dopant elements in lower valence state. The nanomaterials/materials with dopants in lower valence state are important as these exhibit markedly different characteristics than higher valence state materials of same composition. Nanowires show markedly enhanced properties in lateral direction. The invented process presents a procedure for preparation of different types of nanowires in oxide form that are useful for different applications. In this a precursor is ignited in a specially designed container/enclosure that produces the product with the described features. The process is simple and involves a single step/stage is of very short time per batch. The invention provides a process, which gives controlled size of nanowires and is suitable for the production of nanowires/nanomaterials of desired metal oxides with dopant elements in valence state.
US08609051B2 Catalyst composition useful in the catalytic reduction of sulfur compound contained in a gas stream and a method of making and using such composition
Disclosed is a composition useful in the hydrolysis of sulfur compounds that are contained in a gas stream. The composition comprises alumina, a group VI metal component and a group VIII metal component. The composition has a pore structure such that a large percentage of its total pore volume is contained within the pores having a pore diameter greater than 10,000 angstroms.
US08609049B2 Vapour suppression additive
A process for removing CO2 from a CO2 containing gas stream in which the CO2 containing gas stream is contacted with an aqueous ammonium solution. The aqueous ammonia solution comprises 0.1-40% w/v, v/v/w/w ammonia, and a soluble salt at a concentration range of 0.01%-10% wt or v/v or w/v, the soluble salt having cations selected from the group of group IA, IIA, IIIA and IVA metals with counter anions selected from the group of anion of group VIIA elements, NO3−, SO42−, OH−, PO43− and HCO3−. The invention also extends to a CO2 capture solvent comprising an aqueous ammonia solution and the above soluble salt.
US08609048B1 Process for reducing corrosion, fouling, solvent degradation, or zeolite degradation in a process unit
A process for process for reducing one or more of corrosion, fouling, solvent degradation, or zeolite degradation in a process unit is described. The process includes introducing the hydrocarbon feedstream containing oxygen to an adsorbent bed containing copper and reacting the oxygen with the copper to form copper oxide and a reduced oxygen feedstream, and introducing the reduced oxygen feedstream into the process unit. A process for reducing one or more of corrosion, fouling, solvent degradation, or zeolite degradation in an aromatics extraction unit is also described.
US08609045B1 Mercury monitoring system and reaction chamber for enhancing conversion of elemental mercury gas into oxidized mercury
A reaction chamber enables a reaction between received elemental mercury gas and an oxidizing agent gas. The reaction chamber includes a porous (or permeable) medium through which to pass the elemental mercury gas and the oxidizing agent gas. Passing of the elemental mercury gas and the oxidizing agent gas through the porous medium supports a number of useful functions. For example, the porous medium enhances mixing of the elemental mercury gas with the oxidizing agent gas to enhance a reaction. Also, the porous medium increases an amount of surface area in a reaction chamber on which reactions (e.g., heterogeneous surface reactions) can take place between the elemental mercury gas and the oxidizing agent gas to form oxidized mercury gas. Accordingly, the reaction chamber configured to include a porous medium enhances a conversion of elemental mercury gas into oxidized mercury gas.
US08609032B2 Porous ceramic honeycomb articles and methods for making the same
A porous ceramic honeycomb article comprising a honeycomb body formed from cordierite ceramic, wherein the honeycomb body has a porosity P %≧55% and a cell channel density CD ≧150 cpsi. The porous channel walls have a wall thickness T, wherein (11+(300−CD)*0.03)≧T≧(8+(300−CD)*0.02), a median pore size ≦20 microns, and a pore size distribution with a d-factor of ≦0.35. The honeycomb body has a specific pore volume of VP≦0.22. The porous ceramic honeycomb article exhibits a coated pressure drop increase of ≦8 kPa at a flow rate of 26.5 cubic feet per minute when coated with 100 g/L of a washcoat catalyst and loaded with 5 g/L of soot.
US08609028B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
US08609027B2 Air cleaning filter comprising protein deactivating agent and process for producing same
The present invention relates to an air cleaning filter including a carrier provided therein including a protein deactivating agent coated thereon for removing or sterilizing bacteria, fungi, or virus in the air. The present invention also relates to an air cleaning filter further including kimchi lactic acid bacteria and a disinfectant. The present invention also relates to an air cleaning filter further includes fermented Ecklonia cava extract in addition to kimchi lactic acid bacteria and a disinfectant. The air cleaning filter according to the present invention is produced by a method including the step of coating and immobilizing a protein deactivating agent on a carrier, or depending on need, the step of coating and immobilizing a protein deactivating agent, kimchi lactic acid bacteria and a disinfectant on a carrier, or the step of coating and immobilizing a protein deactivating agent, kimchi lactic acid bacteria, a disinfectant and fermented Ecklonia cava extract on a carrier. Or, the air cleaning filter of the present invention includes the step of coating a coating solution on the carrier, the coating solution including protein deactivating agent; the protein deactivating agent, kimchi lactic acid bacteria and disinfectant; or the protein deactivating agent, kimchi lactic acid bacteria, disinfectant, fermented Ecklonia cava extract, wherein the binder is selected from a group including the silicon modified acryl resin, silicon modified epoxy resin, urethane resin, acryl resin, and silicon resin, and, the step of drying the carrier coated thus, whereby permitting to clean air effectively by removing or sterilizing bacteria, fungi, and virus in the air.
US08609026B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
US08609024B2 System and method for automatically venting and sampling a culture specimen container
Apparatus for automated venting and/or sampling of a specimen container is disclosed. The apparatus includes a rack holding the specimen container; a venting and/or sampling device having a needle, a chamber in fluid communication with the needle and a port in fluid communication with the chamber; a robotic transfer mechanism moveable relative to the rack; a sample removal apparatus attached to the robotic transfer mechanism having gripping features for gripping the venting device. The sample removal apparatus and robotic transfer mechanism are moveable relative to the specimen container so as to automatically insert the needle of the venting device through the closure of the specimen container to thereby vent the interior of the specimen container and obtain equilibrium between the interior of the specimen container and the atmosphere and withdraw a portion of the sample from the specimen container into the venting and/or sampling device.
US08609018B2 Electrode for supercapacitor having manganese oxide-conductive metal oxide composite layer, fabrication method thereof, and supercapacitor comprising same
The present invention provides an electrode for a supercapacitor, a fabrication method thereof, and a supercapacitor comprising the same. The electrode exhibits enhanced specific capacitance and electrical conductivity, among others, due to the fact that it comprises a porous composite metal oxide layer which has the structure of a web of entangled nanofibers or has a nanoparticle network structure.
US08609017B2 Electronically tunable, low-loss ceramic materials including a tunable dielectric phase and multiple metal oxide phases
Electronically tunable dielectric materials having favorable properties are disclosed. The electronically tunable materials include an electronically tunable dielectric phase such as barium strontium titanate in combination with at least two additional metal oxide phases. The additional metal oxide phases may include, for example, oxides of Mg, Si, Ca, Zr, Ti and Al. The electronically tunable materials may be provided in bulk, thin film and thick film forms for use in devices such as phased array antennas, tunable filters and the like. The materials are useful in many applications, including the area of radio frequency engineering and design.
US08609016B2 Refoldable balloon and method of making and using the same
The present invention relates to a method of improving balloon refoldability by molding a preformed balloon into a larger, predetermined shape at a lower temperature and higher pressure than that with which the balloon was originally formed.
US08609013B2 Method of fabricating a microfabricated structure
Disclosed herein may be a photosensitive composition, a microfabricated structure including the same, a device including the microfabricated structure, and methods of fabricating the microfabricated structure and the device. The photosensitive composition, including a multifunctional photosensitive resin, a two-photon photosensitizer, an organic solvent, and a silver compound, may be subjected to two- or three-dimensional microfabrication, thus realizing the microfabricated structure containing silver nanoparticles.
US08609006B2 Pattern transfer apparatus and pattern forming method
The pattern transfer apparatus includes: a liquid ejection device having liquid ejection ports through which droplets of liquid are ejected and deposited onto a substrate surface while the liquid ejection device relatively moves to scan the substrate surface in a relative scanning direction; and a stamp having a stamp surface on which a pattern is formed, the stamp surface being applied to the droplets of the liquid on the substrate surface in a stamp application direction while the stamp is relatively moved with respect to the substrate, wherein when defining, on the substrate surface, strips which are straight and parallel to the stamp application direction and have widths substantially equal to diameters of the droplets deposited on the substrate surface, at least one of the strips includes the droplets which are ejected respectively from at least different two of the liquid ejection ports of the liquid ejection device.
US08609005B2 Stretched film of addition polymer consisting of norbornene compound, process for producing the same and use thereof
[Problems] To provide a stretched film of an addition polymer consisting of norbornene compounds favorable for use in manufacturing steps of electric insulating parts and optical parts that exhibits excellent film stability, does not suffer from coloration and has a low linear expansion coefficient.[Means for Solving Problems] A stretched film of an addition polymer consisting of norbornene compounds produced by stretching a film of the addition polymer consisting of norbornene compounds and having a linear expansion coefficient of at most 50 ppm/° C. The draw ratio is preferably from 1.2 times to 10 times. The stretched film is preferably a non-crosslinked film. A method for producing the stretched film comprises stretching a film of the addition polymer consisting of norbornene compounds at least in one direction in an inert gas atmosphere within a temperature range of the glass transition temperature (Tg) thereof ±50° C., or stretching a film of the addition polymer consisting of norbornene compounds containing an organic compound having a specific boiling point at least in one direction.
US08608996B2 Composite sheet materials and processes for manufacturing same
Provided are, among other things, systems, methods and techniques for manufacturing sheet material. In one representative embodiment, a sheet of fabric material is positioned across a patterning template that has a number of openings; and the sheet of fabric material and the patterning template are fed through an extrusion device in which extrusion material coats the fabric material and forces the fabric material into the openings in the patterning template, thereby producing a composite sheet material.
US08608988B2 Curable photochromic compositions and optical articles prepared therefrom
The present invention provides a curable, organic polymeric photochromic composition comprising: a photochromic amount of at least one photochromic material; a polymeric polyol having carbonate groups along its backbone and having a number average molecular weight greater than 5000 g/mole; and a curing agent having reactive functional groups capable of reacting with hydroxyl groups on the polymeric polyol. After curing and after the Photochromic Performance Test the composition demonstrates a T1/2 fade rate of less than 200 seconds.Also provided is a photochromic article comprising a rigid substrate and a photochromic organic polymeric coating applied to a surface of the substrate. The photochromic organic polymeric coating comprises the composition described above.
US08608987B2 High density lithium cobalt oxide for rechargeable batteries
The disclosure relates to positive electrode material used for Li-ion batteries, a precursor and process used for preparing such materials, and Li-ion battery using such material in its positive electrode. The disclosure describes a higher density LiCoO2 positive electrode material for lithium secondary batteries, with a specific surface area (BET) below 0.2 m2/g, and a volumetric median particle size (d50) of more than 15 μm. This product has improved specific capacity and rate-capability. Other embodiments of the disclosure are an aggregated Co(OH)2, which is used as a precursor, the electrode mix and the battery manufactured using above-mentioned LiCoO2.
US08608986B2 Metal complex, polymer compound and device containing those
Disclosed is a metal complex represented by the following formula (1). In the formula, M represents a metal atom; R1-R8 respectively represent a hydrogen atom, a halogen atom or a monovalent group; or alternatively R3 and R4, or R5 and R6 may combine together to form a ring.
US08608985B2 Anisotropic conductive film, composition for the same, and apparatus including the same
An anisotropic conductive film includes a binder part, a curing part, an initiator, and conductive particles, wherein the binder part includes at least one of a nitrile butadiene rubber (NBR) resin and a urethane resin, the binder part having an ion content of more than 0 ppm to about 100 ppm.
US08608984B1 Polymer nano-composites as dry sensor material for biosignal sensing
A multifunctional polymer nano-composite sensor system for detecting various biosignals like ECG and other kinds of signals for sensing strain, temperature and moisture has been disclosed. This sensor system includes (1) a polymer nano-composite sensor material that is flexible, elastic, soft, and conductive, (2) a sensor material fabricated into a desired shape or form, and (3) a signal capturing interface for collecting, transmitting and processing the signals. This sensor system can easily be integrated into a user environment for various user-transparent sensing applications. The present invention more specifically reveals a multi-functional nano-composite sensor for detecting biologically generated electrical signals which is comprised of a polymeric composition having an electrically conductive wire embedded therein, wherein the polymeric composition has a dispersion phase and a dispersed phase, wherein the dispersion phase is comprised of a thermoplastic polymer or a thermoset polymer, wherein the dispersed phase includes an electrically conductive filler, wherein the polymeric composition is gel-free, and wherein the electrically conductive wire is adapted for conveying an electrical signal to a signal processing device. The present invention further discloses a polymeric composition which is comprised of a thermoplastic polyurethane, a styrenic polymer, and at least one electrically conductive filler wherein the styrenic polymer is present in the composition at a level which is within the range of 10 weight percent to 50 weight percent and wherein the electrically conductive filler is present at a level which is within the range of 0.5 weight percent to 40 weight percent, based on the total weight of the polymeric composition.
US08608981B2 Methods for sulfate removal in liquid-phase catalytic hydrothermal gasification of biomass
Processing of wet biomass feedstock by liquid-phase catalytic hydrothermal gasification must address catalyst fouling and poisoning. One solution can involve heating the wet biomass with a heating unit to a pre-treatment temperature sufficient for organic constituents in the feedstock to decompose, for precipitates of inorganic wastes to form, for preheating the wet feedstock in preparation for subsequent removal of soluble sulfate contaminants, or combinations thereof. Processing further includes reacting the soluble sulfate contaminants with cations present in the feedstock material to yield a sulfate-containing precipitate and separating the inorganic precipitates and/or the sulfate-containing precipitates out of the wet feedstock. Having removed much of the inorganic wastes and the sulfate contaminants that can cause poisoning and fouling, the wet biomass feedstock can be exposed to the heterogeneous catalyst for gasification.
US08608979B2 Luminescent particles, methods and light emitting devices including the same
A luminescent particle includes an interior portion of the luminescent particle comprising a luminescent compound that reacts with atmospherically present components and a passivating layer on an outer surface of the luminescent particle that is operable to inhibit the reaction between the luminescent compound and the atmospherically present components.
US08608976B2 Photo alignment material and method of manufacturing display substrate using the same
A photo alignment material includes a photo alignment polymer and an organic solvent. The photo alignment polymer is prepared by polymerizing a diamine monomer including at least two photo reactive parts represented by the following Chemical Formula 1. In Chemical Formula 1, R1 represents —(CH2)n—, —O(CH2)n— or R2, R3 and R4 each independently represent —H, —O(CH2)m—1—CH3 or and n and m independently represent an integer of from 1 to 8. Thus, change of the orientation of the alignment layer due to the action of an electric stress may be prevented and/or reduced. Therefore, an after—image may be reduced, and display quality is improved.
US08608971B2 Method of manufacturing a display substrate
A method of manufacturing a display substrate includes forming a first metallic pattern including gate and storage conductors and a gate electrode of a switching device on a base substrate, forming a gate insulation layer, forming a second metallic pattern and a channel portion including a source line, source and drain electrodes of the switching device, forming a passivation layer and a photoresist film on the second metallic pattern, patterning the photoresist film to form a first pattern portion corresponding to the gate and source conductors and the switching device, and a second pattern portion formed on the storage line, etching the passivation layer and the gate insulation layer, and forming a pixel electrode using the first pattern portion. Therefore, excessive etching of the stepped portion may be prevented, so that a short-circuit defect between a metallic pattern and a pixel electrode may be prevented
US08608970B2 System and method for conditioning a hardwood pulp liquid hydrolysate
A system and method for hardwood pulp liquid hydrolysate conditioning includes a first evaporator receives a hardwood mix extract and outputting a quantity of vapor and extract. A hydrolysis unit receives the extract, hydrolyzes and outputs to a lignin separation device, which separates and recovers a quantity of lignin. A neutralization device receives extract from the lignin separation device and a neutralizing agent, producing a mixture of solid precipitate and a fifth extract. The solid precipitate is removed from the fifth extract. A second evaporator removes a quantity of acid from the fifth extract in a vapor form. This vapor may be recycled to improve total acid recovery or discarded. A desalination device receives the diluted extract, separates out some of the acid and salt and outputs a desalinated solution.
US08608966B2 Method and apparatus for dewatering a mixture of ethanol and water
The invention relates to a method and an apparatus for dewatering mixture of ethanol and water. The method comprises steps for feeding mixture of ethanol and water (1) into an evaporator (2), evaporating said mixture of ethanol and water (1) and feeding a stream of vaporized mixture of ethanol and water (3) to a vapor recompression unit (4), pressurizing vaporized mixture of ethanol and water (3) in the vapor recompression unit (4) and feeding a stream of pressurized vaporized mixture of ethanol and water (5) to a membrane unit (6), and dividing said stream of pressurized mixture of ethanol and water (5) in to a stream of mixture of ethanol and water (8) and into a stream of dewatered mixture of ethanol and water (7).
US08608965B2 Gas actuated mixing system and method
A gas bubble agitated mixing system for viscous fluids comprising: a container (1) in which a viscous fluid (2) may be held; one or more gas pipes (6), each gas pipe having an outlet (8) arranged to introduce gas bubbles (9) into the base region of the container (1), said gas bubbles (9) being of a size suitable to agitate the viscous fluid (2). The system also comprises a moveable carrier arm (4) upon which said one or more gas pipe outlets (8) are mounted; and wherein the movement of the carrier arm (4) causes the position at which each outlet (8) introduces gas bubbles (9) into the container (1) to vary over time.
US08608961B2 Method for affinity chromatography of antithrombin III
The present invention is directed to an affinity chromatography column comprising the antithrombin III (ATIII) protein bound to a solid support, characterized in that: a. the ATIII protein is the wild-type protein or a variant thereof, b. the ATIII protein has been first activated by incubation with an unmodified low-molecular-weight heparin (LMWH) rich in active species, and c. the ATIII protein is covalently bound to a resin in a ratio of less than approximately 2 mg of protein per ml of hydrated resin. The invention is also directed to the use of the aforesaid column for purifying species having an affinity for ATIII in a sample comprising species having affinity and not having affinity for ATIII.
US08608960B2 Method of purifying polypeptides by simulated moving bed chromatography
Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed (“SMB”) system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the SMB methods and apparatus and methods of treatment with the purified immunoreactive compounds.
US08608959B2 Device for picking up objects floating on the water, such as hydrocarbons
A device for picking up floating objects on the water, such as hydrocarbons, has an envelope made of a flexible material impervious to water and to the floating objects, having a mouth at the upstream end and a discharge orifice at the downstream end, a folding rigid framework, arranged inside the envelope and attached thereto at the mouth and at the discharge orifice, at least one inflatable tube attached to the envelope and running along the length of the envelope, and a compressed-gas generation device designed to inflate the or each inflatable tube.
US08608958B2 Flowing water splitting apparatus, flowing water splitting method and sewage system
A flowing water splitting apparatus includes a first flowing water channel including a weir defining a water quantity of the flowing water flowing in from a confluent pipe and leading the flowing water flowing in from the confluent pipe to a dirty water pipe; a second flowing water channel leading flowing water flowing over the weir to a rainwater pipe; a partition wall portion provided to block the flowing water flowing through the first flowing water channel to form a plurality of water diversion chambers partitioned in the first flowing water channel; and a flow throttle portion formed in the partition wall portion to throttle a flow quantity of the flowing water flowing from one water diversion chamber into another water diversion chamber.
US08608957B2 Oil tank
An oil container has a container housing receiving an oil filter and fittings for an oil inlet, an oil outlet, for filling the oil container, and for an opening that can be closed by a cover for temporarily removing or replacing the oil filter, as well as, an air outlet opening. The container housing is divided into at least two chambers by a partition, each chamber including an oil filter. Each chamber has an oil inlet fitting, an oil outlet fitting, and an opening that can be closed by a cover for filling with oil and/or for removing the oil filter. The partition includes an oil overflow opening located above a minimum oil filling level height relative to a rest state determined for the individual oil circuits. A leak occurring in one of the oil circuits does then not affect the operational reliability of the other oil circuit(s).
US08608956B2 Curb inlet catch basin filtration apparatus
A filtration apparatus for curb vaults may be installed in existing vaults through manhole access openings whenever the smallest dimension of the access opening is greater than the smallest dimension measured across a support plate assembly of the filtration apparatus. An adjustable attachment system allows installation of the filtration apparatus by inserting the apparatus through the access opening.
US08608951B2 Process for removing metals from crude oil
A process for removing a metal from a crude oil includes contacting the crude oil containing the metal with a crude-immiscible ionic liquid to produce a crude oil and crude-immiscible ionic liquid mixture, and separating the mixture to produce a crude oil effluent having a reduced metal content relative to the crude oil feed. Optionally, a de-emulsifier is added to at least one of the contacting and separating steps.
US08608946B2 Systems, methods, and catalysts for producing a crude product
Methods and systems for contacting of a crude feed with one or more catalysts produces a total product that includes a crude product are described. The crude product is a liquid mixture at 25° C. and 0.101 MPa. One or more properties of the crude product may be changed by at least 10% relative to the respective properties of the crude feed. The produced crude product may include oxygen, sulfur, residue, or mixtures thereof.
US08608942B2 Systems and methods for residue upgrading
Systems and methods for processing hydrocarbons are provided. A hydrocarbon can be distilled to provide a distillate, a gas oil, and a residue. The residue can include, but is not limited to asphaltenes and non-asphaltenes. The residue can be mixed with a solvent to provide a mixture. The asphaltenes can be selectively separated from the mixture to provide a deasphalted oil. At least a portion of the deasphalted oil and at least a portion of the gas oil can be hydroprocessed to provide a hydroprocessed hydrocarbon. At least a portion of the distillate and at least a portion of the hydroprocessed hydrocarbon can be cracked in a first reaction zone to provide a first cracked product comprising C2 hydrocarbons, C3 hydrocarbons, C4 hydrocarbons, and naphtha.
US08608938B2 Crude product composition
The present invention is directed to a crude composition comprising hydrocarbons having a boiling range distribution of from 30° C. to 538° C., the crude composition having, per gram of crude composition, from 0.01 grams to 0.2 grams of hydrocarbon having a boiling range distribution of at most 204° C., where benzene comprises at most 0.005 grams per gram of the hydrocarbons having a boiling range distribution of at most 204° C., and from 0.000001 grams to 0.05 grams of hydrocarbons having a boiling range distribution of greater than 538° C.
US08608935B2 Apparatus and method for synthesis of alane
One embodiment of the invention includes an electrochemical cell and an externally applied electrical potential used to drive a direct synthesis reaction to produce alane.
US08608931B2 Anti-displacement hard gold compositions
Anti-displacement hard gold compositions are disclosed for inhibiting displacement of metal from substrates which are plated with the hard gold. The anti-displacement hard gold compositions may be used to spot plate substrates with hard gold.
US08608930B2 Electro-blotting devices, systems, and kits and methods for their use
The invention provides an electroblotting system for blotting gels, in which the system includes an electroblotting transfer stack that comprises an analysis gel and a blotting membrane, an anode, an ion source juxtaposed with the anode between the anode and the transfer stack, a cathode, and another ion source juxtaposed with the cathode between the cathode and the transfer stack, in which the each ion source is sufficient for electrophoretic transfer. The anode, the cathode, or both can be separate from a power supply and provided as part of a disposable electrode assembly that also includes a body of gel matrix that includes ions for electrophoretic transfer.
US08608926B2 Amperometric in-pipe electrochemical sensing probe
A sensing probe intended to measure the content of an oxygen reducible substance in a fluid, includes: a probe body containing an interface and processing circuit, a dry sensing head including an amperometric sensor intended to measure the content of the oxygen reducible substance. The sensing head is removable. The sensing head and the probe body include respectively coupling elements cooperating with each other and able to be separated, and the sensing probe furthermore includes connecting elements designed to connect the removable sensing head to the interface and processing circuit of the probe body.
US08608921B2 Layered enzyme compositions for use with analyte sensors
Embodiments of the invention provide amperometric analyte sensors having optimized elements such as electrodes formed from sputtered platinum compositions as well as layers of material selected to optimize the characteristics of a wide variety of sensor elements and sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.
US08608920B2 Electrochemical biosensor strip and method for identifying a corresponding biosensing device by said strip
The present invention relates to an electrochemical biosensor strip comprising a base which has a front side and a back side, an electrode system on the front side of said base, a code-recognition element on one end of the back side of said base, a cover which is located on said electrode system, and a reaction area which is in touch with said electrode system for a reaction to take place. By forms of said code-recognition element provided in the present invention, a biosensing device will automatically choose a specific set of calibration code corresponding to a particular batch of the electrochemical biosensor strip while coupling to the strip. Hence, the present invention eliminates the calibration step carried out by users and simplifies the measuring procedure, avoiding the inaccurate results due to the omission or improper operation of the calibration step by users. The present invention further relates to a method for identifying a corresponding biosensing device by using a ratio of lengths of each length-changeable area of the strip.
US08608910B2 Coal reforming apparatus
A coal reforming apparatus includes: a dryer body provided to dry low-quality coal; a pyrolysis body which pyrolyzes the dried coal thus dried; and a briquetter which compression-molds the pyrolyzed coal thus pyrolyzed. The coal reforming apparatus has a radical scavenger supplier which supplies drying gas with a radical scavenger so that the low-quality coal can be dried in an atmosphere containing the radical scavenger, the drying gas being supplied from a drying gas supply source and heated by a heater, the radical scavenger being formed of an organic compound having a hydroxyl group.
US08608909B2 Advanced dewatering system
A permeable belt for use in a system for dewatering and/or drying a fibrous web. The permeable belt capable of being subjected to a tension of at least approximately 30 kN/m, the permeable belt having at least one side having an open area of at least approximately 25% and a contact area of at least approximately 10%.
US08608908B2 Method and system using low fatty acid starches in paper sizing composition to inhibit deposition of multivalent fatty acid salts
A method for inhibiting deposition of multivalent saturated fatty acids on paper sizing equipment and/or devices which use a paper surface sizing composition containing higher starch solids levels of surface sizing starches and a source of multivalent cations, such as a multivalent metal drying salt, by including (wholly or partially) one or more low fatty acid surface sizing starches in the paper surface sizing composition. Also, a paper surface sizing system for carrying out this method.
US08608907B2 Fluorescent whitening agent compositions
A composition suitable for paper brightening, wherein the composition contains one or more specified fluorescent whitening agents with taurine groups. The composition is used for whitening paper, in particular at the wet-end, in the size press or by coating.
US08608902B2 Plasma processing apparatus
A vertical plasma processing apparatus for performing a plasma process on a plurality of target objects together at a time includes an activation mechanism configured to turn a process gas into plasma. The activation mechanism includes a vertically elongated plasma generation box attached to a process container at a position corresponding to a process field and confining a plasma generation area airtightly communicating with the process field, an ICP electrode disposed outside the plasma generation box and extending in a longitudinal direction of the plasma generation box, and an RF power supply connected to the ICP electrode. The ICP electrode includes a separated portion separated from a wall surface of the plasma generation box by a predetermined distance.
US08608898B2 Multilaminar wood veneer block, multilaminar wood veneers and method for the manufacture thereof
Multilaminar wood block from which to obtain multilaminar wood veneers by means of a slicing operation comprising a plurality of superimposed wood veneers (2), and a plurality of layers (3) of adhesive alternating with the veneers (2) to stably connect a veneer (2) with an adjacent veneer (2). The layer (3) of adhesive is formed from a glue free from formaldehyde.
US08608896B2 Liquid adhesive lamination for precision adhesive control
Methods for liquid adhesive lamination for precision adhesive control are provided. Precision liquid adhesive control can be obtained by first patterning liquid adhesive in a thin pre-coat layer on a substrate. A second adhesive layer can then be patterned on top of the pre-coat layer. When the second substrate is pressed onto the first substrate, the second substrate first comes into contact with the second adhesive layer. The adhesive can then be spread uniformly across the two substrates without forming voids. Alternatively, a single liquid adhesive layer can be formed in a three dimensional gradient pattern.
US08608892B2 Method for making a color display device
A method of making a color display device and color display device are provided for the display of metallic or special effect pigmented paint using commercially available or the manufacturer's paint. In the method provided herein, the metallic or special effect pigmented paint is sprayed onto a web behind a knife or onto a first roller which is a part of a roller roller coater.
US08608890B2 Reconfigurable shape memory polymer tooling supports
A method and support apparatus for providing structural support to a mold or mandrel, such as a shape memory polymer (SMP) apparatus configured for shaping a composite part. The support apparatus may comprise a rigid structural member and a plurality of SMP cells attached thereto and configured to inflate or deploy in a malleable state toward and against a surface of the SMP apparatus, mold, or mandrel. Then the SMP cells may be returned to a rigid state while still pressed against this surface, thereby providing structural support when composite material is applied to an opposite surface of the SMP apparatus, mold, or mandrel. After the composite material is cured into the finished composite part, the SMP cells may be deflated or otherwise collapse toward the structural member to provide enough clearance to be removed from the cured composite part.
US08608889B2 Method for handling adhesive laminate sections
A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method.
US08608887B1 Slip-on corner protectors for picture frames and machine and method of making same
A slip-on corner protector for rectangular picture frames includes a flat cardboard pre-form which is bent into the shape of a hollow prism having right triangularly-shaped front and rear frame face cover panels joined at vertical and horizontal sides thereof by a vertical and horizontal rectangularly-shaped frame edge cover panel, respectively. Triangularly-shaped spring flaps bent inwardly from hypotenuse edges of the front and rear triangular panels are pressed against and thus grip a frame inserted between the front and rear triangular panels because of the elasticity of the cardboard pre-form. A machine and method for manufacturing corner protectors from a stack of pred-forms bends panels perpendicularly upwards from a pre-form by linear actuators, spays a hot melt adhesive blob onto an upright panel, and presses it against another upright panel to form an adhesive bond.
US08608886B2 Method for connecting a first component to a second component
A method for connecting a first component to a second component, the method including: applying a fastening dome composed of material in a viscous state to the first component, hardening the fastening dome on the first component, and then inserting a connecting element through the first component, second component, and at least partially through the fastening dome.
US08608885B2 Substrate heat treatment apparatus
A substrate heat treatment apparatus includes a heat-treating plate having a flat upper surface, support devices formed of a heat-resistant resin for contacting and supporting a substrate, a seal device disposed annularly for rendering gastight a space formed between the substrate and heat-treating plate, and exhaust bores for exhausting gas from the space. The support devices are formed of resin, and the upper surface of the heat-treating plate is made flat, whereby a reduced difference in the rate of heat transfer occurs between contact parts and non-contact parts on the surface of the substrate. Consequently, the substrate is heat-treated effectively while suppressing variations in heat history over the surface of the substrate.
US08608883B2 Adherent layer
The present disclosure describes embodiments of an adherent layer that may be used to attach a geo-membrane to a concrete slab and methods that include installation of the adherent layer. The adherent layer can be used to inhibit the geo-membrane from becoming disengaged with the concrete slab and can thereby help prevent water from penetrating the geo-membrane and causing moisture damage to the structure above.
US08608881B2 Method of forming a breast prosthesis
A breast prosthesis is formed by providing a core of low density foam, shaping the core in the general form of a breast, and applying an outer layer of resilient skin to an outer side of the core to substantially resemble a breast. The inner side of the core opposite the outer side is shaped for mating engagement with a user. A plurality of interchangeable covers of flexible material are each arranged to releasably span the inner side of the core. Typically, coloring is provided on the outer side to resemble an areola of the breast and a protrusion arranged to resemble a nipple of the breast is releasably adhered to the outer side at various positions relative to the areola.
US08608879B1 Environmentally friendly flare illuminant composition
The present invention is a flare illuminant composition, useful in hand-held signals, which composition is environmentally friendly and economical, containing a commercially available, aromatic, high energy, amine-based organic compound, 5-aminotetrazole, in place of the conventional and toxic KClO4, or, for the known alternative to KClO4, expensive, strontium bis-(1-methyl-5-nitriminotetrazolate)monohydrate.
US08608876B2 AA7000-series aluminum alloy products and a method of manufacturing thereof
An AA7000-series alloy including 3 to 10% Zn, 1 to 3% Mg, at most 2.5% Cu, Fe<0.25%, and Si<0.12%. Also, a method of manufacturing aluminum wrought products in relatively thick gauges, i.e. about 30 to 300 mm thick. While typically practiced on rolled plate product forms, this method may also find use with manufacturing extrusions or forged product shapes. Representative structural component parts made from the alloy product include integral spar members, and the like, which are machined from thick wrought sections, including rolled plate.
US08608875B1 Sponge-iron alloying
A steel manufacturing process can include forming an iron oxide layer on a hot band during hot rolling; reducing the iron oxide layer on the hot band to form a sponge iron layer that includes pores; the sponge-iron layer having a thickness in a range of about 0.05 μm to about 1000 μm, about 0.1 μm to about 100 μm, or about 5 μm to about 25 μm; and depositing an alloying element into the pores of the sponge iron layer to form an impregnated sponge-iron layer. The process can further include annealing the impregnated sponge-iron layer to produce an iron alloy layer carried by the substrate.
US08608874B2 Spring steel and method for manufacturing the same
Disclosed is high strength spring steel that can limit the depth of pitting occurring when corroded and therefore possesses high strength as well as excellent pitting corrosion resistance and corrosion fatigue property, with a composition containing: C: greater than 0.35 mass % and less than 0.50 mass %; Si: greater than L75 mass % and less than or equal to 3.00 mass %; Mn: 0.2 mass % to 1.0 mass %; Cr: 0.01 mass % to 0.04 mass %; P: 0.025 mass % or less; S: 0.025 mass % or less; Mo: 0.1 mass % to 1.0 mass %; and 0: 0.0015 mass % or less, under a condition that a PC value calculated by PC=4.2×([C]+[Mn])+0.1×(1/[Si]+1/[Mo])+20.3×[Cr]+0.001×(1/[N]) is greater than 3.3 and equal to or less than 8.0. Also disclosed is a preferred method for manufacturing the same.
US08608872B2 High-strength stainless steel pipe excellent in sulfide stress cracking resistance and high-temperature carbonic-acid gas corrosion resistance
The problem to be solved is the provision of a high-strength stainless steel pipe having a sufficient corrosion resistance in a high-temperature carbonic acid gas environment and having an excellent sulfide stress cracking resistance at normal temperature. A high-strength stainless steel pipe consist of, by mass %, C: 0.05% or less, Si: 1.0% or less, P: 0.05% or less, S: less than 0.002%, Cr: more than 16% and 18% or less, Mo: more than 2% and 3% or less, Cu: 1% to 3.5%, Ni: 3% or more and less than 5%, Al: 0.001% to 0.1% and O: 0.01% or less, Mn: 1% or less and N: 0.05% or less, and Mn and N in the above ranges satisfy formula (1), and the balance being Fe and impurities; and the metal micro-structure of the stainless steel pipe mainly includes a martensitic phase and comprises 10 to 40% of a ferritic phase by volume fraction and 10% or less of a retained γ-phase by volume fraction. [Mn]×([N]−0.0045)≦0.001  (1) wherein the symbols of elements in formula (1) respectively represent the contents (unit: mass %) of the elements in the steel.
US08608870B2 Carburization heat treatment method and method of use
Disclosed is a carburization heat treatment method including carburizing a workpiece at a relatively low temperature within a temperature range of A1˜A3 using a vacuum carburizing furnace and then performing quenching using a high-pressure gas, in which the workpiece is made of typical carburizing alloy steel having a carbon content of about 0.10˜0.35 wt %. This method can be applied to carburization heat treatment of a steel workpiece sensitive to heat deformation, such as an annulus gear, in lieu of a conventional gas carburization method using plug quenching.
US08608867B2 Individualized jewelery alloys and method for their production
A method for the individualization of a metallic material by means of a carbon-containing basic material of organic origin is proposed. The novel method makes it possible to produce individualized ornamental alloys and individualized symbolic articles, such as pieces of jewelry, in a first step a carbon-containing organic basic material, which originates from at least one specific clearly identifiable person or a clearly identifiable group of persons, being converted into a carbonized initial material, and, in a second step, a physical and chemical incorporation of at least a fraction of the carbonized initial material into the metallic material taking place. The novel method and the novel ornamental alloys make it possible to produce symbolic articles with a direct material or substantive relation to a desired person by simple means, without creative freedom being restricted.
US08608866B2 Detergent dispenser for improved detergent removal
Embodiments of the present invention are related to a detergent dispenser configured to attach to an interior surface of a dishwasher door. The detergent dispenser may comprise a reservoir configured to hold detergent, wherein a portion of the upper wall of the reservoir has been removed to reduce a cross-sectional length thereof such that water flowing down the dishwasher door is encouraged into the reservoir. The detergent dispenser may also comprise a dispenser door comprising a closed configuration and an open configuration, wherein the dispenser door is configured to cover the reservoir in the closed configuration. The detergent dispenser may be configured to encourage water flowing down the interior surface of the dishwasher door to enter the reservoir when the dispenser door is in the open or closed configuration.
US08608864B2 Substrate treating method
A substrate treating method for treating substrates with a treating liquid includes a deionized water cleaning step for supplying deionized water from an injection pipe and cleaning the substrates inside a cleaning tank with deionized water, then a replacing step for injecting a solvent from a solvent injector and replacing the deionized water with the solvent, a separating and removing step for switching a channel to a branch pipe and causing a separator to remove the deionized water from the treating liquid, and an adsorbing and removing step for switching the channel to another branch pipe and causing a deionized water remover to adsorb and remove the deionized water from the treating liquid.
US08608862B2 Clean in place gassing manifold
A method for cleaning a gassing manifold includes providing a gassing module and a complementary clean in place module for coupling to the gassing module. Cleaning solution is pumped from the clean in place module to the gassing module above a minimum flow rate and velocity for effective cleaning.
US08608860B2 Adhesive compositions capable of completely removing acari, bacteria, moths, ticks, fleas from fabrics and animal's hair
A method for removing microorganisms and small insects from fabric or animal's hair comprising applying and removing an adhesive composition comprising at least one adhesive polymer and a plasticizer, wherein the amounts of this plasticizer range from about 5 to about 45% by weight of the total weight of the wet adhesive composition.The adhesive composition used in the method of the invention thanks to the presence of high plasticizer concentrations are very fluid to allow said micro-organisms or small insects to be removed and, at the same time, they leave no residue on the fabric, or animal's hair.The present invention further relates to adhesive compositions to be used in the method of the invention further containing active ingredients which are released from the adhesive composition during the step of removing the organisms from the fabric or the animal's hair.
US08608858B2 Substrate cleaning apparatus and method for determining timing of replacement of cleaning member
A substrate cleaning apparatus includes a cleaning apparatus 10 including an abutting member which is to be pressed against a cleaning member to clean the cleaning member, a drive control device for controllably driving the abutting member, and a cleaning tank which contains a cleaning liquid and allows a portion of abutment between the cleaning member and the abutting member to be impregnated with the cleaning liquid. The substrate cleaning apparatus also includes an image capturing device which captures a surface image of the cleaning member and an image processing device. A surface condition of the cleaning member is monitored to determine the timing of replacement of the cleaning member. The substrate cleaning apparatus further includes a measurement device which measures the number of particles and/or a concentration of a component in the cleaning liquid in the cleaning tank. Results of measurement by the measurement device are fed back to a drive control device, to thereby prevent contamination of the cleaning member.
US08608853B2 Thermal reactor with improved gas flow distribution
Embodiments of the present invention provide apparatus and method for improving gas distribution during thermal processing. One embodiment of the present invention provides an apparatus for processing a substrate comprising a chamber body defining a processing volume, a substrate support disposed in the processing volume, wherein the substrate support is configured to support and rotate the substrate, a gas inlet assembly coupled to an inlet of the chamber body and configured to provide a first gas flow to the processing volume, and an exhaust assembly coupled to an outlet of the chamber body, wherein the gas inlet assembly and the exhaust assembly are disposed on opposite sides of the chamber body, and the exhaust assembly defines an exhaust volume configured to extend the processing volume.
US08608851B2 Plasma confinement apparatus, and method for confining a plasma
A plasma confinement apparatus, and method for confining a plasma are described and which includes, in one form of the invention, a plurality of electrically insulated components which are disposed in predetermined spaced relation, one relative to the others, and surrounding a processing region of a plasma processing apparatus, and wherein a plurality of passageways are defined between the respective insulated components; and at least one electrically conductive and grounded component forms an electrical field shielding for the processing region.
US08608850B1 Low-energy, hydrogen-free method of diamond synthesis
Diamond thin films were deposited on copper substrate by the Vapor Solid (VS) deposition method using a mixture of fullerene C60 and graphite as the source material. The deposition took place only when the substrate was kept in a narrow temperature range of approximately 550-650° C. Temperatures below and above this range results in the deposition of fullerenes and other carbon compounds, respectively.
US08608849B2 Method for making zinc oxide nano-structrure
A method for making zinc oxide nano-structure, the method includes the following steps. Firstly, providing a growing device, the growing device comprising a heating apparatus and a reacting room. Secondly, providing a growing substrate and forming a metal layer thereon. Thirdly, depositing a catalyst layer on the metal layer. Fourthly, placing the growing substrate into the reacting room together with a quantity of zinc source material. Fifthly, introducing a oxygen-containing gas into the reacting room. Lastly, heating the reacting room to a temperature range of 500˜1100° C.
US08608846B2 Liquid silicone rubber coating composition, curtain airbag, and its production method
A liquid silicone rubber coating composition exhibiting high adhesion for an airbag base fabric; a curtain airbag having a silicone rubber coating layer of the cured composition formed on at least one surface of the base fabric; and a method for producing such curtain airbag are provided. The composition comprises (A) an organopolysiloxane having at least 2 alkenyl groups bonded to the silicon atoms per molecule; (B) an organohydrogenpolysiloxane having at least 2 structural units represented by formula (1) per molecule, the structural units being linked by a non-siloxane structural unit not containing SiH group; (C) an addition catalyst; (E) an organosilicon compound having an epoxy group and an alkoxy group bonded to the silicon atom in the molecule; and (F) a titanium compound and/or a zirconium compound; and preferably (D) a fine powder silica having a specific surface area of at least 50 m2/g.
US08608845B2 Cutback asphalt compositions and products comprising an extender derived from tall oil, and methods for making and using same
Cut back asphalt compositions and product wherein the cutting solvent comprises a tall oil based solvent and optionally other renewable solvents.
US08608840B2 Choke assembly
A choke assembly comprises an inlet (48) for a multiphase fluid stream, the stream comprising a first relatively heavy fluid phase and a second relatively light fluid phase; a first fluid outlet (116); a choke element (22) disposed between the inlet and the first fluid outlet operable to control the flow of fluid between the inlet and the first fluid outlet; a separation chamber (40, 114) disposed to provide separation of phases in the fluid stream upstream of the choke element; and a second outlet (118) for removing fluid from the separation cavity. The choke assembly is of particular use in the control of fluid streams produced from a subterranean well, in particular oil and gas produced from a subsea well.
US08608838B2 Tubing air purification system
The invention provides an air purification system in form of tubing, by which particulates of various sizes in the air flow can be collected. The system includes an air inlet, an air outlet and a particulate removing unit located therebetween, the particulate removing unit including a tubing array of material having low dielectric constant, when an air flow passes through the system electrostatic effect is created between the air flow and the tubing material so as to remove the particulates entrained within the air flow. The invention also provides a method for removing particulates from air flow using the electrostatic effect created between the air flow and said material.
US08608836B2 Integral hydrogen and air purifier
A gas purifier assembly for providing first (50) and second (38) purified gas streams having an integral heater (54). The assembly can have two separate chambers for gaseous fluid flow for the purpose of purifying a gas stream of hydrogen (34), for example, and a separate distinct stream of gas such as compressed air (46). A centrally located heater heats the first chamber to effect purification of the first gas. Waste heat from the first chamber is transferred to the second chamber via conduction to effect purification of the second gas stream.
US08608835B2 Exhaust gas purification system for an internal combustion engine
An exhaust gas purification system for an internal combustion engine of a motor vehicle is provided. The system includes a first particulate filter element and a second particulate filter element, which is connected downstream of the first particulate filter element and through which flows the exhaust gas that emanates from the first particulate filter element. The first particulate filter element operates as a system filter and the second particulate filter element operates as a diagnostic filter. A charge of the diagnostic filter can be determined, and the functional capability of the system filter can be deduced based thereon.
US08608832B2 Apparatus for concentrating and diluting specific gas and method for concentrating and diluting specific gas
One ozone concentrating chamber is provided therein with a part of a cooling temperature range where ozone can be selectively condensed or an oxygen gas can be selectively removed by transmission from an ozonized oxygen gas, and a part of a temperature range where condensed ozone can be vaporized, and condensed ozone is vaporized by moving condensed ozone with flow of a fluid or by gravitation to the part where condensed ozone can be vaporized, whereby the ozonized oxygen gas can be increased in concentration. Such a constitution is provided that a particle material 13 for condensation and vaporization filled in the ozone concentrating chambers 11 and 12 has a spherical shape of a special shape with multifaceted planes on side surfaces, or an oxygen transmission membrane 130 capable of selectively transmitting an oxygen gas in an ozone gas is provided.
US08608826B2 Method of modeling fly ash collection efficiency in wire-duct electrostatic precipitators
The method of modeling fly ash collection efficiency in wire-duct electrostatic precipitators provides for the optimization of fly ash collection through the generation of numerical solutions to the electrostatic and electrodynamic equations associated with the particular geometry of the wire-duct electrostatic precipitator. Particularly, the solutions are developed through use of the finite element method and a modified method of characteristics.
US08608824B2 Integrated method for producing carbonyl iron powder and hydrocarbons
Integrated process, in which pure carbonyl iron powder (CIP) is prepared by decomposition of pure iron pentacarbonyl (IPC) in a plant A, carbon monoxide (CO) liberated in the decomposition of the IPC is used in plant A for the preparation of further CIP from iron or is fed to an associated plant B for the preparation of synthesis gas or is fed to an associated plant C for the preparation of hydrocarbons from synthesis gas, and the CIP prepared in plant A is used as catalyst or catalyst component in an associated plant C for the preparation of hydrocarbons from synthesis gas from plant B.
US08608821B2 Method for the production of fertilizer and CO2
The invention provides a method for the combined production of (i) a fertilizer selected from the group consisting of ammonium nitrate, ammonium phosphates or a combination thereof, (ii) a concentrated stream of CO2 through an indirect neutralization of ammonia with an acid selected from the group consisting of nitric acid, phosphoric acid, a salt thereof and a combination thereof; said method comprising: (I) reacting a carbonate product with a reagent selected from the group consisting of nitric acid, phosphoric acid, a salt thereof, and a mixture thereof to form CO2, and a fertilizer containing an ammonia component; and (II) separating at least a portion of said carbon dioxide from said fertilizer in a condensed and relatively concentrated stream.
US08608820B2 Filter for filtering particulate matter from exhaust gas emitted from a compression ignition engine
A filter for filtering particulate matter (PM) from exhaust gas emitted from a compression ignition engine, which filter comprising a porous substrate having inlet surfaces and outlet surfaces, wherein the inlet surfaces are separated from the outlet surfaces by a porous structure containing pores of a first mean pore size, wherein the porous substrate is coated with a wash coat comprising a plurality of solid particles comprising a molecular sieve promoted with at least one metal wherein the porous structure of the wash coated porous substrate contains pores of a second mean pore size, and wherein the second mean pore size is less than the first mean pore size.
US08608818B2 Filter element having sealing members and methods
A filter arrangement includes a media construction comprising a corrugated sheet secured to a flat sheet rolled into a coiled construction. A frame and a first seal member are provided. The frame secures the first seal member to the coiled construction. The first seal member is preferably oriented to form a radial seal with a housing. A second seal member is secured to the outer annular surface of the coiled construction. The second seal member includes a gasket extension having first and second opposite ends; an attachment portion; and a protrusion extending from the attachment portion. The second seal member is preferably oriented to form an axial seal with a housing. Air cleaners preferably utilizing filter arrangements as described herein operably installed within housings. Methods of installing, filtering, assembling, and servicing preferably include arrangements as described herein.
US08608816B2 Fluid filtration device and system
A medical fluid filter system is provided having a housing having: a liquid trap chamber having a volume; a filter media chamber; a filter media arranged within the filter media chamber; the liquid trap chamber having a liquid trap outlet port in fluid communication with the filter media chamber; the liquid trap outlet port configured and arranged within the liquid trap chamber to inhibit flow of liquid from the liquid trap chamber to the filter media chamber and configured and arranged to allow gas to flow from the liquid trap chamber to the filter media chamber; a filter system inlet passing through the housing for intake of fluid originating from a surgical site; and a filter system outlet passing through the housing for fluid exhaust.
US08608815B2 Methods of fabricating polycrystalline diamond compacts
Embodiments relate to methods of manufacturing polycrystalline diamond compacts (“PDCs”). In an embodiment, a method of fabricating a PDC includes positioning a plurality of diamond particles adjacent to a cemented carbide material. The cemented carbide material includes one or more types of tungsten-containing eta phases. The method further includes subjecting the plurality of diamond particles and the cemented carbide material to a high-pressure/high-temperature process effective to sinter the plurality of diamond particles so that a polycrystalline diamond table is formed without tungsten carbide grains of the cemented carbide material exhibiting abnormal grain growth that project into the polycrystalline diamond table.
US08608814B2 Systems and methods for reliable feedstock delivery at variable delivery rates
Hydrogen-producing fuel processing assemblies and methods for delivering feedstock to a hydrogen-producing region of a hydrogen-producing fuel processing assembly. In some embodiments, the fuel processing assemblies include a feedstock delivery system that includes a pump assembly and a stall prevention mechanism that is adapted to reduce pressure in an outlet conduit during periods in which the pump assembly is not emitting a liquid outlet stream within or above a hydrogen-producing pressure range. In some embodiments, pressure in the outlet conduit is isolated from pressure in the hydrogen-producing region of the fuel processing assembly and is reduced during periods in which a liquid stream is not being pumped within or above a hydrogen-producing pressure range.
US08608813B2 Method of manufacturing solid fuel mainly including synthetic resin-pulp scrap
Disclosed are eco-friendly and low-price solid fuel, which is naturally dried, and a method of manufacturing the same. Disposable diapers or disposable sanitary pads, which are failed during the manufacturing process, are used to produce industrial alternative fuel having a low price through a predetermined process, so solid fuel having no pollution problem in combustion is provided. The solid fuel is mainly made of synthetic resin-pulp scrap including synthetic resin integrated with pulp like the disposable diapers or the disposable sanitary pads. The method includes introducing a scrap, such as the wasted disposable diaper or the wasted disposable sanitary pad, including synthetic resin integrated with pulp into a crusher to break the scrap into fragments, adding a slight amount of waste cooking oil serving as a binding agent to the fragments, performing an extrusion-molding with respect to the fragments, cutting the extrusion-molded fragments to make pallets, and then drying pallets.
US08608811B2 Composition and process for oxidative colouring keratin fibers
The present invention relates to a process for oxidative coloring keratin fibers especially human hair wherein dyeing composition comprises a cross linked copolymer. The objective of the present invention is a process for oxidative coloring hair wherein compositions A and B are mixed, composition A comprises at least one oxidative dye precursor and optionally at least one coupling agent and optionally at least one direct dye in a cosmetically acceptable medium and composition B comprises at least one oxidizing agent in a cosmetically acceptable medium, and applied onto hair and processed for 1 to 45 min at a temperature range of 20 to 45° C. and rinsed off from hair, wherein at least one of the two compositions A and B comprises a cross linked copolymer of vinylpyrrolidone, vinylimidazol, 3-methyl-1-vinylimidazolium and methacrylic acid.
US08608810B2 Hair colorant compositions comprising 3-amino-2,6-dimethylphenol and 1,4-phenylenediamine-type developers, methods, and kits comprising the compositions
A hair colorant composition comprises 3-amino-2,6-dimethylphenol in combination with a second dye coupler selected from the group consisting of 2,6-dihydroxyethylaminotoluene, 2,6-diaminopyridine and a developer selected from the group consisting of 2-methyl-1,4-benzenediamine, 2-methyl-1,4-benzenediamine sulfate salt, p-phenylenediamine, p-toluenediamine, hydroxyethyl-p-phenylenediamine, N,N-bis(hydroxyethyl)-p-phenylenediamine, 2-methoxymethyl-1,4-benzenediamine. A kit for coloring hair comprises the hair colorant composition. A method of treating hair comprises applying the hair colorant composition to hair.
US08608803B2 Implant derived from bone
An implant which is particularly suitable for the repair and/or replacement of a skeletal joint, e.g., a vertebral joint, includes a unit of monolithic bone possessing at least one demineralized region exhibiting properties of flexibility and resilience, the demineralized region having diminished or insignificant capacity for promoting new bone growth.
US08608802B2 Implantable devices for subchondral treatment of joint pain
Devices and associated methods are disclosed for treating bone, and particularly bone tissue at the joints. Disclosed are implantable devices that can be used either alone or in combination with this augmentation or hardening material for the repair of bone defects and which are particularly suited for use at the joints, and even more particularly, suited for use at the subchondral bone level.
US08608801B2 Osteochondral implants, arthroplasty methods, devices, and systems
Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
US08608800B2 Switchable diffractive accommodating lens
A lens in accordance with the present invention includes an accommodating cell having two chambers with at least one chamber filled with optical fluid with the refractive index matching the refractive index of the accommodating element separating them. The accommodating element has a diffractive surface with surface relief structure that maintains its period but changes its height due a pressure difference between the chambers to redirect most of light that passes through the lens between different foci of far and near vision. The invention also includes a sensor cell that directly interacts with the ciliary muscle contraction and relaxation to create changes in pressure between the accommodating cell chambers that results in changing surface relief structure height and the lens accommodation.
US08608799B2 Umbrella-shaped accommodating artificial ocular lens (AAOL) device
An accommodating artificial ocular lens (AAOL) device including a lens optic portion connected to a pleated lens haptic portion to provide accommodation of vision of the eye.
US08608797B2 Mitral valve treatment techniques
Apparatus (20) is provided for treating mitral valve regurgitation, including a band (30) having distal and proximal ends, the band (30) adapted to be placed: around between 90 and 270 degrees of a mitral valve (58), including around at least a portion of a posterior cusp (56) of the valve (58), in a space defined by (a) a ventricular wall (70), (b) a ventricular surface of the posterior cusp (56) in a vicinity of an annulus (60) of the mitral valve (58), and (c) a plurality of third-order chordae tendineae (74). The apparatus (20) further includes distal and proximal coupling elements (32, 34), coupled to the band (30) at the distal and proximal ends thereof, respectively, and adapted to be coupled to a first chorda tendinea and a second chorda tendinea, respectively, each of the first and second chordae tendineae selected from the group consisting of: one of the plurality of third-order chordae tendineae (74), and a first-order chorda tendinea that inserts on a commissural cusp (78) of the mitral valve (58). Additional embodiments are also described.
US08608794B2 Flexible stent with improved axial strength
A stent comprises a generally cylindrical band having a pattern of alternating first and second struts, the first struts being wider than the second struts, the first and second struts being of substantially the same length.
US08608793B2 Energized stents and methods of using the same
The present disclosure relates to surgical systems including energized/energizable stents, and methods of using the same in the prevention of restenosis. A surgical system for treating a stenosis and/or a restenosis site s provided. The surgical system includes an electrosurgical generator; an energy transmitting conduit connectable to the electrosurgical generator; and a stent positionable in a body lumen at a site of a stenosis. The stent is fabricated from an electrically conductive material and adapted to electrically communicate with the electrosurgical generator, and the energy transmitting conduit delivers electrosurgical energy to the site of the stenosis.
US08608790B2 Bifurcation catheter and method
A catheter assembly for treatment of a vessel bifurcation. The catheter assembly is adapted for use with a single guidewire, wherein the guidewire is used to both position the catheter assembly within a main vessel of the vessel bifurcated and then be advanced into a branch vessel of the vessel bifurcated. A guidewire lumen of the catheter assembly is defined by a portion of a catheter shaft of the catheter assembly and a portion of a side catheter branch of the catheter assembly. The side catheter branch extends from a distal end of the catheter shaft at a proximal location and is connected at a distal location to a main catheter branch. After the catheter assembly has been advanced over the guidewire to a position within the main vessel at the vessel bifurcation, the guidewire is retracted, a portion of the side catheter branch is advanced into the branch vessel, and the guidewire is advanced into the branch vessel.
US08608786B2 Apparatus for delivering multiple forms of electromagnetic radiation and method for its use
An apparatus for delivering multiple forms of electromagnetic radiation and methods for its use are disclosed. An example embodiment may comprise a radiation unit having one or more light emitting diodes that emit electromagnetic radiation in continuous wave form and one or more laser diodes that emit electromagnetic radiation in continuous wave form. The radiation unit may be connected to a frequency generator that provides a waveform. The waveform may convert the continuous wave output of the laser diodes to pulse wave output, while leaving the continuous wave output of the light emitting diodes unaffected. The frequency generator may cause the emission of an additional electromagnetic field proximate the radiation unit. Associated apparatuses and methods for their use are also provided.
US08608785B2 Hammer toe implant with expansion portion for retrograde approach
An implant for fusing adjacent bones is disclosed. The implant includes an elongate threaded member and a flexible portion extending from the elongate threaded member. The flexible portion includes a plurality of prongs configured to be reversibly compressed toward an axis defined by the elongate threaded member.
US08608783B2 Bone plate with flange member and methods of use thereof
Aspects of the present disclosure include a bone plate and/or a bone plate system. The bone plate includes an elongate body, which elongate body includes a top and a bottom surface as well as a distal portion, a proximal portion, and an intercalating portion disposed between the distal and proximal portions. The elongate body also includes a flange member, which flange member is configured for contacting a bone portion, e.g., a fractured bone portion, so as to aid in the stabilization and correct anatomical reduction thereof.
US08608778B2 Intervertebral stabilization system
An intervertebral stabilization system for at least three vertebraecomprising pedicle screws attachable to the vertebrae; at least one rod for the connection of at least two pedicle screws to form a rigid stiffening system; and at least one band which is capable of being pre-stressed in tension and which is surrounded in the implanted state of the stabilization system by at least one compressible pressure member arranged between two adjacent pedicle screws for the connection of the pedicle screws to form an elastic support system, wherein a common pedicle screw is associated both with the stiffening system and with the support system and the band is can be connected or is connected to the rod by means of a band attachment.
US08608777B2 Method and apparatus for coupling soft tissue to a bone
A method for coupling soft tissue to bone including: positioning a first anchor in a first bone bore, the first anchor having a first self-locking adjustable suture construct including a first adjustable loop, a second adjustable loop, and a pair of first ends; positioning a second anchor in a second bone bore, the second anchor having a second self-locking adjustable suture construct including a third adjustable loop, a fourth adjustable loop, and a second end; positioning the first adjustable loop relative to the soft tissue; positioning the second adjustable loop about the third adjustable loop; and tensioning the pair of first ends and the second end to pull the first adjustable loop against the soft tissue, couple the second adjustable loop to the third adjustable loop, pull the second adjustable loop against the soft tissue, and pull the third adjustable loop against the soft tissue.
US08608776B2 Reduced-pressure, abdominal treatment systems and methods
A reduced-pressure abdominal treatment system has an open-cavity treatment device for providing reduced-pressure treatment proximate a patient's abdominal contents; a deep-tissue closure device for applying a closing force on a deep-tissue wound on a patient's fascia; a surface-wound closure subsystem for providing a closing force on a surface wound on the patient's epidermis; and a reduced-pressure supply subsystem operable to develop a reduced pressure. Methods are also included.
US08608775B2 Two part tape adhesive for wound closure
A wound closure device includes a first applicator including a handle portion and a substrate engaging portion and a second applicator including a handle portion and a substrate engaging portion. A first substrate is releasably couplable to the substrate engaging portion of the first applicator and includes a tissue reactive surface and a self-reactive surface. A second substrate is releasably couplable to the substrate engaging portion of the second applicator and includes a tissue reactive surface and a self-reactive surface. The self-reactive surfaces of the first and second substrates each possess reactive groups known to have complementary functionality for bonding the first and second substrates together.
US08608774B1 Bifurcated forceps
The bifurcated forceps is a tweezers-like instrument having two elongate, flattened arms joined at their mutual proximal ends, and each arm extends to a distal end having two laterally separated tines extending therefrom. The mutually facing surfaces of the corresponding tines of each arm are provided with serrations or teeth along the majority of their lengths, the facing serrations meshing with one another. The bifurcated forceps may have laterally straight arms, or laterally curved arms. Reusable forceps may be formed of surgical steel, and disposable forceps may be formed of a suitable plastic. The laterally separated tines enable the bifurcated forceps to grip a portion of tissue or other matter simultaneously at two separate points, thereby holding a greater span of the tissue clear of the underlying structure to facilitate surgical procedures and the like.
US08608771B2 Vascular occlusion device with enhanced feedback
A vascular occlusion device for occluding a body cavity includes an elongate member, a deflecting device and an indicator device. The elongate member includes a proximal end and a distal end. An embolization material is injected into the body cavity through the distal end. The deflecting device is disposed at the distal end of the elongate member and configured to be deflected by the embolization material. The indicator device is disposed at the proximal end of the elongate member. The indicator device indicates a status of occlusion of the body cavity based on deflection of the deflecting device by the embolization material.
US08608770B2 Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.
US08608763B1 Method for minimally invasive tendon sheath release
A device and method for minimally invasive tendon sheath release. The device and method that enables a surgeon to cut (“open”) a pulley that is obstructing a nodule and keeping a tendon from sliding smoothly. A ball tipped guide probe goes through a small incision and is used to find the edge of the pulley. Once found, the probe is guided to an end of the pulley. After proper position is assured, a cutting blade is deployed by pushing and holding a blade deployment switch. This deploys the sharp end of a retractable cutting shaft beyond the sheath. The entire device is then pushed or pulled using the device handle along the pulley until the pulley is completely released or where resistance is no longer felt. In an alternate embodiment, the cutting blade is static.
US08608762B2 Translaminar approach to minimally invasive ligament decompression procedure
Provided herein is a method for treating spinal stenosis comprising percutaneously accessing the epidural space from a first side of the spine. The first side of the spine is located on one side of the medial plane with respect to the spinal cord. A tissue removal tool is then advanced through the first side of the epidural space into the other side of the epidural space, where the other side of the epidural space is located on the other side of the medial plane of the spinal cord. Once the tissue removal tool is located on the second side of the medial plane, stenosis can be reduced using the tissue removal tool.
US08608759B2 Medical devices for suturing biological tissue
Medical devices for cutting and suturing biological tissue generally include a shaft and first and second guide members each including a first portion coupled to the shaft at a first location and a second portion coupled to the shaft at a second location. The first portions are movable along the shaft relative to the second portions, and the first and second guide members define an arcuate profile and are configured to flex in response to such movement. When used to cut tissue, the medical device may further include a blade positioned between the first and second guide members. When used to suture tissue, one or more suture guides may be provided on the first guide member for directing a suture needle through tissue proximate the first guide member. Methods of repairing and replacing a meniscus using the medical devices are also provided.
US08608757B2 Apparatus and method for hair removal
An apparatus and method for removing hair from the surface of skin may include two elongate elements entwined with one another whereby a local mutual twist is formed along the length of the elements. Each of the elements may be held in place and put into tension by a respective one of two structural members. A method for removing hair may include moving the two structural members with the elements in tension, bringing the bottom end of one member closer to the bottom end of the second member such that the coil travels toward the bottom ends of the elements, and then bringing the top end of one member closer to the top end of the second member, such that the coil travels toward the top ends of the elements. As the coil travels between the top and bottom ends of the elements, it extracts hairs from the skin.
US08608756B2 Disc for an epilating apparatus disc assembly
A disc for an epilating apparatus disc assembly includes at least one clamping portion intended to interact with a further clamping portion of a neighboring disc when the disc and the epilating apparatus are arranged as the epilating apparatus-disc assembly, with a radially outward region of the clamping portion. The radially outward region and a radially inward region are harder than a radially intermediate region of the clamping portion.
US08608755B2 Dermatome with width plate captures
A dermatome having a main body, a blade assembly and a bottom member, where the main body includes a bottom surface and at least one capture extending from the bottom surface. The bottom member may be inserted into the at least one capture and fastened to the main body, where the blade assembly may be mounted between the fastened bottom member and the bottom surface of the main body. The captures of the main body may limit the movement of the inserted bottom member in at least three general directions and the fastener may limit the movement of the bottom member in at least a fourth general direction.
US08608753B2 Retractable tip for vitrectomy tool
A probe for a vitrectomy tool is provided having a vitreous cutter tube having a blunt tip at a distal end and adapted to be coupled at a proximal end to a handpiece of a vitrectomy tool; a retractable outer trocar tube surrounding the vitreous cutter tube having an open distal end with a sharpened edge; and a retraction mechanism coupled to a proximal end of the outer trocar for selectively extending and retracting the outer trocar tube between a first extended position wherein the sharpened edge of the outer trocar is extended beyond the blunt tip of the vitreous cutter tube to facilitate insertion into the eye and a second retracted position wherein the sharpened edge of the outer trocar is retracted behind the blunt tip of the vitreous cutter tube to facilitate safe operation of the probe.
US08608750B2 Surgical device for injecting cement in a bone cavity
A surgical device and method for injecting cement in a bone cavity includes an elongated, hollow body to be inserted partially into the cavity. The body has an inner lumen with a distal opening to expel cement therefrom. An entry plug for the cement is connected to a cement pressurized supply. The entry plug is in fluid communication with the lumen to deliver cement through the entry plug, wherein the entry plug is movably mounted on the hollow body.
US08608746B2 Derotation instrument with reduction functionality
Instruments and methods are provided for manipulating a bone anchor and a spinal fixation element. The instruments and methods disclosed herein are particularly suited to facilitate rotation of a bone anchor relative to another bone to correct the angular rotation of the vertebrae attached to the bone anchor. The instrument does not require the spinal fixation element to be inserted into the bone anchor prior to manipulation. The instrument further may be used in the insertion of the spinal fixation element into the bone anchor.
US08608744B2 Methods and apparatus for acetabular arthroplasty
A method for performing an acetabular arthroplasty in an acetabulum of an ilium may include locating an iliac canal of the ilium. The iliac canal extends from the surface of the acetabulum generally toward a portion of the iliac ridge. An impacting step impacts a non-rotating bone removal tool aligned along the iliac canal such that the non-rotating bone removal tool removes bone within the iliac canal and forms a bone void. Another step secures a fixation implant within the canal void. An acetabular implant is installed within the acetabulum over the fixation implant.
US08608738B2 Apparatus for treating a portion of a reproductive system and related methods of use
A medical device for performing a surgical procedure may include an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The medical device may also include a handle connected to the proximal end of the elongate member, an end effector assembly connected to the distal end of the elongate member, and a cutting device configured to extend from the end effector assembly, wherein the cutting device has a retracted configuration in which the cutting device is withdrawn into the end effector assembly and a deployed configuration in which the cutting device extends from the end effector assembly.
US08608737B2 Methods for applying energy to tissue using a graphical interface
The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.
US08608736B2 Steerable catheters and methods for making them
Apparatus are provided for performing a procedure within a patient's body that include a tubular member including proximal and distal ends, a central axis or region extending therebetween, and a distal portion extending distally from an intermediate portion to the distal end. One or more accessory lumens and a steering element lumen extend between the proximal and distal ends, the steering element lumen offset from the central region within the distal portion such that a steering plane intersects the steering element lumen and the central axis. The distal portion includes a core member extending between the intermediate portion and the distal end, and stabilization elements embedded in the core member adjacent the accessory lumen and defining a stabilization plane that intersects the steering plane at a location offset from the central region, e.g., closer to the accessory lumen than the steering element lumen.
US08608733B2 Electrosurgical apparatus with predictive RF source control
An electrosurgical generator is disclosed, which includes a closed loop control system having a sensor system configured to sense tissue and/or energy properties at a tissue site and to generate a sensor signal representative of the tissue and/or energy properties. The control system includes a controller configured to select an electrosurgical operational mode from a plurality of electrosurgical operational modes in response to the sensor signal. A radio frequency arbitrary source is also included which generates a radio frequency input signal corresponding to the selected electrosurgical operational mode and a radio frequency output stage configured to generate a treatment signal corresponding to the electrosurgical operational mode. The system includes a predictive signal processor configured to adjust the radio frequency output stage in response to the radio frequency input signal, such that the radio frequency output stage alters the treatment signal in real time based on the selected electrosurgical operational mode.
US08608732B2 Flammable substance sensing during a surgical procedure
A surgical safety apparatus for use in connection with an energizable surgical device minimizes inadvertent activation of a surgical tool when the oxygen or flammable gas level is too high. An activation circuit is connected with an energy source and with a hand piece of the tool. A sensor measures the oxygen or flammable gas near the tool and can operate in a first state to disconnect the energy source from the hand piece. In a second state the source of energy is connected to the hand piece. The sensing element is connected to the activation circuit. The sensing element signals the activation circuit to convert the activation circuit from the first state to the second state provided the oxygen or flammable gas level is safe.
US08608728B2 Delivery system and method
A connector and method of connecting are described for connecting a first and second catheter at an overlap area where the first catheter fits within the second catheter. The connector includes a collar that surrounds a portion of the overlap area and a clamp that applies a radially inward force to the collar and encircles a portion of the overlap area.
US08608727B2 Delivery system and method
A connector and method of connecting are described for connecting a first and second catheter at an overlap area where the first catheter fits within the second catheter. The connector includes a collar that surrounds a portion of the overlap area and a clamp that applies a radially inward force to the collar and encircles a portion of the overlap area.
US08608726B2 Vascular guidewire control apparatus
A controller for use with a guidewire, such as a vascular guidewire, provides a mechanism for gripping and applying a torque to the guidewire without the need to thread the guidewire axially through the controller and at a location close to a point of access of the guidewire. In one embodiment, the controller includes a side-access, multi-part assembly including a collet or other gripping element that applies a uniform radially inward force on the guidewire. In another embodiment, for use with guidewires having active electrically controllable elements, the controller integrally or removably incorporates a switch or other mechanism to initiate an energized state. The controller thereby permits ergonomic, single-handed control of an electronically steerable guidewire, including axially displacing, torquing and steering the guidewire.
US08608725B2 Eluting coils and methods of deploying and retrieving
Embodiments are directed to eluting coils having a relaxed coiled state and a straightened state that may be deployed at a fixed location within a patient's body and may accurately dispense and distribute fluids and or dissolvable substances at site specific locations of the body. Some embodiments of eluting elements are configured to be subsequently retrieved from a delivery site.
US08608722B2 Container for an anal irrigation system
The present invention relates to a container for anal irrigation. In particular it relates to a rigid container which is easy to operate and which easily is transformed from a storage configuration to a ready-to-use configuration. In one aspect the invention relates to a container for an anal irrigation system. The anal irrigation system comprises an anal probe; a reservoir for holding an irrigation liquid (e.g. water); a pump mechanism for pumping a fluid (e.g. air) into the reservoir; and a liquid tube connecting the reservoir with the anal probe. The container comprises an outer chamber wall, defining at least partly the outer dimensions of the container and an inner chamber wall arranged within the outer chamber wall, said outer chamber wall and inner chamber wall defining the reservoir. This provides a reservoir having a small surface area when filled with irrigation liquid. Thus only a low pressure is necessary to evacuate the irrigation liquid from the reservoir and out through the anal probe.
US08608718B1 Urine collection bag holder
A urine collection bag holder including a fabric strip having a hip portion and a leg portion depending therefrom and a pouch removably attached to the leg portion wherein the pouch receives a urine collection bag therein, in order to conceal the urine collection bag beneath a user's clothes. A belt that slidingly engages a continuous belt opening within the hip portion and a pair of leg straps secure the device to a user. A plurality of slits and a tube opening disposed in the leg portion receive and guide a cathether tube therethrough to connect with an upper receptacle.
US08608717B2 Urine collection apparatus
A urine collection apparatus includes a urine cover, a buffer member, and a pipe. The urine cover has an edge, a room therein, and an opening and an aperture communicated with the room, and a user's penis enters into the room via the opening. The buffer is connected to the edge of the urine cover with a connecting surface thereon to be in touch with the user's skin. The pipe is connected to the aperture of the urine cover to direct urine to a desired location.
US08608715B2 System and method to vent gas from a body cavity
One aspect of the invention is a method to vent gas from a body cavity during an endoscopic procedure. A body cavity is in fluid communication with an exhaust gas inlet of a vacuum break device. The vacuum break device has a chamber in fluid communication with both the inlet and an outlet. The chamber may comprise one or more openings in fluid communication with the atmosphere. A conduit in fluid communication with the exhaust gas outlet may be connected directly or indirectly to a suction source. The suction source may be activated.
US08608713B2 Septum feature for identification of an access port
An access port for providing subcutaneous access to a patient, and a method of identifying a subcutaneously implanted access port. The access port includes a body capturing a septum that covers a cavity defined by the body, and a pattern of protrusions extending from an outer surface of the septum away from the cavity, the pattern of protrusions detectable through palpation to identify the access port as a power-injectable port.
US08608711B2 Infusion port
Disclosed is an infusion port for regulating the inflow of an aqueous solution of an aqueous-solution pack into an external ringer spike as at least part of the ringer spike is inserted or withdrawn. The infusion port comprises an inflow part, a securing part, and a cover part. The inflow part is formed with at least one first inflow hole into which the ringer spike is inserted, so as to allow the inflow of the aqueous solution of the aqueous-solution pack as the ringer spike is inserted. Consequently, as the first inflow hole of the inflow part moves outside or inside the securing part, it is possible to regulate the flow of the aqueous solution of the aqueous-solution pack through the first inflow hole and into the ringer spike disposed inside the inflow part.
US08608709B2 Injection device for apportioning set doses
The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a dose setting member (20, 70) which is screwed out from the housing (30) to set a dose and pushed axially back to the housing (30) in order to expel the set dose. A scale drum (80) is axially and inrotatable coupled to the dose setting member (20, 70) such that the scale drum (80) is rotated up a thread (34) when the dose setting member (20, 70) is rotated to set a dose. When the dose setting member (20, 70) is pushed axially back to its initial position to inject the set dose, the scale drum (80) is released from its inrotatable connection in order to allow the scale drum (80) to rotate down the thread (34) and back to its zero position.
US08608705B2 Catheter securement device
A securement system (100) includes a device which permits a portion of a catheter or similar medical article to be easily anchored to a patient, desirably without the use of tape or needles and suture. A securement system for an elongated medical article comprises an anchor pad (110) and a retainer (120) mounted upon the anchor pad. The retainer (120) includes a channel (130) that has at least one abutment surface (160) corresponding to a contact surface on the medical article and a groove (210) configured to receive a spline (40) of the medical article. The medical article is placed into the channel (130). The medical article is secured within the channel by retaining at least one spline (40) and contact surface on the medical article.
US08608700B2 Microfabicated electromagnetic actuator with push-pull motion
A micromechanical electromagnetic actuator may have two separate components: a flux-generating portion and a separate movable structure. The flux-generating portion may have a plurality of conductive coils wound around a magnetically permeable material. Each coil generates a magnetic field along its axis, which is different for each of the coils. The adjacent movable structure may include magnetically permeable features, one inlaid in the movable structure and other stationary features which focus the flux produced by the flux-generating mechanism across a gap between the stationary features. By energizing each coil sequentially, a push-pull motion in the actuator may result from the force of the magnetically permeable features. This push-pull actuator may be particularly effective when used as a pumping element in a drug delivery system, or other fluidic pumping system.
US08608697B2 Insertion indicator for needle
A method and apparatus are provided for a fluid level insertion indicator that provides immediate feedback to a surgeon by draining when a tip of a needle has entered a body lumen, such as peritoneal cavity. An apparatus includes a handle connected to a hollow needle and a hollow stylet that extends through the hollow needle and has a blunt distal end that includes an opening for passing fluid. A spring biases the stylet to extend past the sharp distal end of the needle absent resistance by tissue against the stylet. An at least partially translucent pressure chamber configured to hold a quantity of fluid under pressure is connected to the proximal end of the stylet. The pressure chamber and stylet form a conduit for passing fluid through the opening in the blunt distal end when the stylet extends past the sharp distal end of the hollow needle.
US08608693B2 Tamper evident needle guard for syringes
A medicine injection device comprises a cartridge having a cartridge barrel and a plunger having a plunger shaft slidable within the cartridge barrel. The cartridge may have, e.g., a pre-filled medicine. The medicine injection device farther comprises a body having a proximal end, a distal end, and a cavity in which the cartridge barrel is disposed. The proximal end of the body may optionally form a finger grip. The medicine injection device further comprises a plunger locking mechanism attached to the proximal end of the body. The plunger locking mechanism comprises a member with an aperture slidably engaged with the plunger shaft. The locking mechanism is configured for preventing the plunger from being removed from the cartridge barrel. For example, the plunger shaft may include a locking stop, e.g., a flange, that engages with the aperture in an interference arrangement.
US08608692B2 Fluid collection self-locking, self-blunting safety needle system and syringe
The invention is related to a particular type of safety needle and syringe. The needle has a locking device which can be used with or without a syringe. The needle is cylindrical with one surface flattened out. The Blunting member is aligned within the needle. With the intake of fluids the blunting instrument moves out, blocks the needle tip and locks inside the needle. Thus preventing reuse and needle stick Injury.
US08608691B2 Angioplasty method and means for performing angioplasty
An angioplasty procedure wherein a balloon dilatation catheter is movably positioned within an anchoring catheter and which in turn is located within a guiding catheter or wherein a balloon dilatation catheter is movably positioned within a guiding catheter and the anchoring catheter in turn is positioned on the external surface of the guiding catheter, or wherein a balloon dilatation catheter is movably positioned within a catheter which serves both as a guiding catheter and anchoring catheter. Additionally, valve elements are attached to the guiding and anchoring catheters to provide points of securement between the catheters and the balloon dilatation catheter and to prevent the backflow of blood through the catheter assembly. Actuation of the valve elements allows a doctor to control the movement of the catheters.
US08608687B2 Multi-lumen endoscopic accessory and system
The embodiments of the present invention relate to an endoscopic system and accessories. In particular, the various embodiments relate to endoscopic systems in which an accessory comprises a multi-lumen device that is capable of quantitatively delivering at least a catheter, a balloon, and a needle to a site. The accessory is configured to allow for individual, independent control of its components. For example, in some embodiments, the needle and guidewire can be independently controlled. In addition, the needle may be retracted back into an inner lumen of the catheter body. Accordingly, during use, the accessory of the embodiments allows the user to maintain access to an incision site without having to exchange or remove accessories for various parts of the procedure.
US08608684B2 Impulse chamber for jet delivery device
The invention provides a jet expelling assembly comprising a reservoir and an impulse chamber assembly. The impulse chamber assembly comprises a chamber portion defining a cavity having a general axis, a piston received in the cavity along the general axis and comprising a fluid inlet, thereby defining a variable-volume impulse chamber with an outlet nozzle. The inlet comprises a conduit adapted to slidably engage a reservoir outlet during relative movement therebetween. The chamber portion is arranged stationary relative to the reservoir, whereby expelling an amount of drug from the reservoir to the impulse chamber via the inlet causes the piston to move towards the reservoir, the impulse chamber thereby receiving the expelled amount of drug.
US08608683B2 Device for infusion of at least two medicaments
A device for infusing of at least one medicament includes at least two actuators configured to cause at least two medicaments to be infused; at least one sensor configured to measure a value of at least two parameters; and a controller configured to control the at least two actuators, wherein the controller is programmed to activate the at least two actuators depending on the values of each of the at least two parameters, and wherein the controller is arranged so as to consider a dependency of the at least two medicaments.
US08608682B2 Method and device for irrigation of body cavities
A pressure and a vision regulation method and device for irrigation of a body cavity (1), in which method an inflow liquid pump (2) pressurizes the irrigation liquid in a feed line (13) and in which an outflow device (3) or an external suction source (20) drains the irrigation liquid from the body cavity (1) through a tubing (16) into a waste container (17) and in which a control unit (4) controls either the inflow liquid pump (2) only or both the inflow liquid pump (2) and the outflow device (3) depending on an inflow irrigation liquid pressure from a pressure sensor (5), where the first control unit (4) compares the inflow irrigation liquid pressure and flow with pressures calculated to correspond to pressure in the body cavity for the respective flow for a nominal surgical site and that a matching between the calculated values and the inflow irrigation liquid pressures is made by altering the effect of either the inflow liquid pump (2) only or the inflow liquid pump (2) and/or the outflow device (3) and/or the shut off valve. The above-mentioned pressure registration method and the device for irrigation of a body cavity is combined with an method for detecting blood cells, red blood cells, haemoglobin and/or debris in liquid coming from a surgical site so an automatically control and rinsing system is achieved keeping a clear vision in the viewing area of the operational site.
US08608677B2 Device for carrying the load of injured soft tissue
The present invention relates to the field of therapeutic and/or injury support devices. In one form, the invention relates to a device for the relative protection and treatment of injured muscles, tendons and other soft tissue, as well as a method of utilizing this device. In one particular form, the present invention relates to providing an external support structure to assist in the load carrying function of injured soft tissue.
US08608673B2 Bathtub for beauty and health care and a physic solution
The present patent application provides a bathtub for beauty and health care and a physic solution. The bathtub comprises a housing and a tub which is formed by an inner tub and an outer tub nested together, there is a clearance between the inner tub and the outer tub, at least a group of ultrasonic generating elements are arranged on the wall of the outer tub and used for generating ultrasonic so as to vibrate water inside the outer tub and then vibrate physic solution inside the inner tub. Beauty and health care for a whole body can be realized by filling the physic solution into the inner tub, meanwhile, when a user is soaking in the physic solution, the physic solution is vibrated along with the ultrasonic generating elements, so that the physic solution can be introduced into the body effectively. In order to keep the temperature of the never goes too high or too low, a circulating pump is used to flow the physic solution circularly. Safe insulation effect is achieved by using hot water in the outer tub to heat the physic solution in the inner tub. The ultrasonic generating element can be controlled according to the actual situation and requirement of the user, and individual records and individual control for user can be realized, so that intelligent control performance of the bathtub for beauty and health care can be improved.
US08608664B2 Electrode
An object of the present invention is to provide a microelectrode capable of recording action potentials of nerve cellsneurons as large-amplitude waveforms and being appropriate for multi-channeling. The electrode 1 of the present invention comprises a conductive linear core material 2, an insulating coating layer 3a with which the outer circumference of the linear core material is coated, and an extending part 3b formed by extending the end part of the coating layer on one tip side of the linear core material beyond the tip in the longitudinal direction of the linear core material, in which a cavity that opens in the extending direction is formed within the extending part.
US08608663B2 Pulse wave period measuring apparatus, pulse wave period measuring method, heartbeat period measuring method, and recording medium
A pulse wave period measuring apparatus according to an embodiment of the present invention detects a pulse wave of a subject, detects a maximum value and a minimum value in a predetermined period of the pulse wave, calculates one or more reference values between the maximum value and the minimum value in the predetermined period, based on one or more internally dividing ratios common to plural predetermined periods of the pulse wave, calculates two or more times in the predetermined period, the apparatus calculating the two or more times at which the pulse wave intersects with the one or more reference values, calculates a time period between each calculated time in the predetermined period and a corresponding calculated time in a last period before the predetermined period, as a pulse wave period of the pulse wave, calculates a variation of pulse wave periods, for two or more pulse wave periods calculated between the predetermined period and the last period before the predetermined period, and calculates, based on the variation of the pulse wave periods, the stability of measuring the pulse wave periods.
US08608662B2 Ultrasound diagnosis apparatus
An apparatus has: an ultrasound probe that transmits and receives ultrasound waves to and from a subject and has an ultrasound transmission/reception surface; an acoustic coupler that has a different shape for each type and is attachable and detachable so as to cover the ultrasound transmission/reception surface; a generator that, based on the ultrasound waves received by the ultrasound probe, generates an image expanding in a depth direction from the ultrasound transmission/reception surface; and an analyzer that, based on presence/absence and shape of an acoustic coupler region within the image generated by the generator, identifies presence/absence of mounting of the acoustic coupler and a type of the mounted acoustic coupler. Consequently, the apparatus is capable of identifying the acoustic coupler though the ultrasound probe and the acoustic coupler are not provided with special structures.
US08608651B2 Access device for minimally invasive surgery
A retractor has a proximal portion comprising a first side portion having a first longitudinal edge and a second side portion having a second longitudinal edge. The first and second portions being movable relative to each other such that the first and second longitudinal edges can be positioned in close proximity to each or spaced apart by a selected distance. A distal portion has an outer surface and an inner surface partially defining a passage. The distal portion is capable of having a configuration when inserted within the patient wherein the cross-sectional area of the passage at a first location is greater than the cross-sectional area of the passage at a second location, wherein the first location is distal to the second location.
US08608649B2 In-vivo visualization system
Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.
US08608648B2 Articulation joint
A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories.
US08608647B2 Systems and methods for articulating an elongate body
Systems and methods for articulating an elongate articulatable body which is adapted to be delivered within a body cavity. Particularly, systems and methods for enhancing an articulating force on the elongate body without increasing an actuation force applied by an actuator.
US08608644B1 Remote interactive sexual stimulation device
A therapeutic adult cyber sex toy for use over the internet incorporating the premise of video chat interaction with programming capable of supporting interpersonal sexual experience utilizing a set of communicating controllers produced in the form of male and female genitalia. The controllers of the present invention correlate to that of the partner. The male's controller is in the form of a mock vagina having an optical sensor at its opposed end along with buttons for inducing commands in a linked female's controller, the female controller is in the form of a dildo and has a similar command interface for interacting with the male's controller. Partners are capable of affecting each others experience by varying settings in the others controller while using their own, such variables can include vibration, heat, auditory/video feedback and frequency.
US08608642B2 Methods and devices for treating morbid obesity using hydrogel
An environmentally sensitive hydrogel material swells or collapses in response to a parameter such as pH level associated with consumption of food by a patient. This swelling or collapsing is harnessed to treat morbid obesity or some other condition of the patient. The swelling or collapsing of the hydrogel may be used to tighten a gastric band or gastric valve when the patient starts eating; then loosen the band or valve when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to increase the size of a space occupying device in the patient's stomach when the patient starts eating; then decrease the size of the space occupying device when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to selectively restrict the absorption of nutrients within a patient's gastrointestinal tract, such as in the duodenum.
US08608640B2 Implantable sling for the treatment of incontinence and method of using the same
A method of treating urinary incontinence includes forming a first incision exposing a urethral region a patient and forming first and second suprapubic incisions. The method includes tunneling an introducer from the first suprapubic incision superficially anterior to a pubic symphysis of the patient and out of the first incision, attaching a first portion of an implant to the introducer and retracting the introducer and the first portion of the implant from the first incision to the first suprapubic incision, and repeating these maneuvers on the contralateral side. The method includes forming third and fourth incisions and tunneling a suitable introducer from the third/fourth incisions through separate obturator foramen of the patient to allow retracting portions of the implant from the first incision back through to the third/fourth incision with the introducer.
US08608639B2 Resilient device
An intravaginal device has a working portion (e.g., intravaginal urinary incontinence device suppository, tampon) and an anchoring portion comprising at least one member extending beyond at least one end of the working portion to maintain the working portion in place during use.
US08608638B2 Methods and systems for treating tinnitus
Methods and systems for treating tinnitus are provided. Some embodiments include a method of providing a primary audio signal having a primary peak portion substantially centered at about a tinnitus frequency of a patient. The method may also include combining the primary audio signal with a general audio signal to generate a combined sound. The method may also include exposing the patient to the combined sound so that the patient hears the combined sound, to diminish a perception by the patient of tinnitus.
US08608636B2 Ventricular assist device cannula and ventricular assist device including the same
Provided is a ventricular assist device cannula, and more particularly, a ventricular assist device cannula with electrodes. An exemplary embodiment of the present invention provides a ventricular assist device cannula with electrodes, including: a connecting tube connecting an incision of a body tissue and a ventricular assist device so that blood can flow; and electrodes connected with the connecting tube and contacting the incision of the body tissue to transfer an electric signal to the body tissue.
US08608635B2 TET system for implanted medical device
A TET system is operable to vary an amount of power transmitted from an external power supply to an implantable power unit in accordance with a monitored condition of the implantable power unit. The amount of power supplied to the implantable power unit for operating a pump, for example, can be varied in accordance with a cardiac cycle, so as to maintain the monitored condition in the power circuit within a desired range throughout the cardiac cycle.
US08608634B2 Coil for magnetic stimulation and methods for using the same
A magnetic stimulator, which may be used as a transcranial magnetic stimulation (TMS) device, and a method for its use are disclosed. The stimulator comprises a frame and an electrically conductive coil having a partially toroidal or ovate base and an outwardly projecting extension portion. The frame may be a flexible or malleable material and may be nonconductive. The electrically conductive coil may comprise one or more windings of electrically conductive material (such as a wire) coupled to the frame. The coil is electrically connected to a power supply. The device may be placed adjacent to or in contact with the body of a subject, such as on the head of a subject. The device may be used on humans for treating certain physiological conditions, such as cardiovascular or neurophysiological conditions, or for studying the physiology of the body. This device is useful in studying or treating neurophysiological conditions associated with the deep regions of the brain, such as drug addiction and depression.
US08608619B2 Automatic transmission and control method therefor
When the temperature of oil supplied to an electrical oil pump is detected and the oil temperature is lower or higher than normal oil temperature, a gradient threshold value smaller than that at normal oil temperature is set, a gradient of a road surface on which a vehicle is stopped is detected, and an idle stop is prohibited when the detected gradient of the road surface is larger than the set gradient threshold value.
US08608615B2 Drive system, in particular for a motor vehicle
A drive system has a dual clutch transmission with two component transmissions, a dual clutch and an output shaft. The two component transmissions have a common main shaft and each has one component transmission input shaft that can be connected operatively to the main shaft. The main shaft and the output shaft are connected operatively to one another. A combustion engine selectively can be connected operatively to one of the component transmissions via the dual clutch and one of the component transmission input shafts to drive the output shaft via the main shaft. An electric machine can be connected positively and operatively to one of the component transmission input shafts and/or to the output shaft, or can be connected positively and operatively to one of the component transmission input shafts and/or to the main shaft.
US08608614B2 Actuation system for a drive unit of a motor vehicle
An actuation system for a drive unit of a motor vehicle includes a control unit which is assigned to the drive unit and which has a function level, a function monitoring level, and having a power output stage for actuating the drive unit or actuators or sensors which are assigned to the drive unit. To relieve the function a data transmission device for outputting data to a data bus is arranged in the function monitoring level. The data transmission device can output a drive setpoint torque to the drive unit, to actuators or sensors which are assigned to it, or to a power output stage (9, 9′) of a separate, second drive unit.
US08608612B2 Planetary gear train of automatic transmission for vehicles
A planetary gear train of an automatic may include an input shaft, an output shaft, a first planetary gear set having a first, second and third rotation elements, the first selectively connected to the input shaft, a second planetary gear set having a fourth, fifth and sixth rotation elements, the fourth directly connected to the second rotation element and the fifth directly connected to the input shaft, a compound planetary gear set having seventh, eighth, ninth and tenth rotation elements, the seventh selectively receiving the speed of the input shaft from the fifth, the eighth selectively receiving increased speed from the sixth, the ninth directly connected to the output shaft, and the tenth selectively connected to the input shaft, eight rotation members consisting of at least one of the rotation elements and six friction members.
US08608610B2 Transmission unit
The present invention relates to a transmission unit for a vehicle driven by muscle force, comprising an input shaft which can be connected to cranks on opposite sides for driving the vehicle, comprising a first partial transmission. The first partial transmission comprises a countershaft, wherein a plurality of driving gear wheels is mounted on the input shaft, and wherein a corresponding plurality of driven gear wheels of the first partial transmission is mounted on the partial transmission shaft. The driven gear wheels of the first partial transmission are designed as idler gears that can be connected to the countershaft by means of shifting means in a rotationally rigid manner. The countershaft forms an input shaft of a second partial transmission. A plurality of second drive wheels are mounted on the output shaft, wherein the second partial transmission comprises an output shaft, on which a corresponding plurality of second driven gear wheels are mounted.
US08608609B2 Symmetrical traction drive
Disclosed is a symmetrical traction drive that utilizes multi-diameter rollers having traction surfaces for transferring rotational mechanical energy between the shaft and a transfer gear. Multi-diameter rollers are mounted in carriers disposed between two substantially symmetrical ring gears. Sloped traction surfaces of the ring gears mate with inner traction surfaces on both sides of the multi-diameter rollers. Since force is applied to the inner traction surfaces on both sides of the multi-diameter rollers, forces are substantially equalized on each side of the multi-diameter rollers. An outer traction surface of the multi-diameter roller interfaces with a traction surface on the shaft. Speed reduction ratios of at least 20:1 or greater can be achieved. The high speed drive may include exhaust turbines, steam turbines, including a Tesla turbine or Schumacher turbine, compressors, combinations of turbines and compressors, high speed pumps, dentist drills, or other devices that operate with high rotational speed.
US08608608B1 Apparatus for multiplying torque
An apparatus consisting of a motor with a cylindrical housing homocentric to the drive shaft of the motor. A pinion is affixed concentrically to the front end of the motor housing. The motor housing is fitted with bearings which allows the motor housing to rotate inside its support housing when torque is applied. Idler gears set in a frame perpendicular to the drive shaft mesh with the pinion attached to the motor housing, and link that pinion to a similar pinion affixed to the drive shaft of the motor. When the drive shaft is coupled to a workpiece and torque is applied the opposing force generated by the torque causes the motor housing and its pinion to rotate in the opposite direction. The idler gears linking the similar pinions redirects that opposing force toward the torque initiated by the motor thus compounding the amount of energy being applied to the workpiece.
US08608606B2 Transmission device having power splitting
A transmission device having power splitting. In the first driving range, the mechanical power branch transmits torque from the ring gear to the additional fixed gear by the fixed gear. In this case, power branches from the ring gear. The hydrostatic power branch branches from the second sun gear. The hydrostatic branch transmits power from the first to the second hydraulic unit. The first and second hydraulic units act respectively as a pump and a motor. On one of the hydrostatic shafts, the mechanical and hydrostatic powers are added and transmitted to the output. In the second driving range, power from the planet carrier partially branches to the ring gear and passes to the hydrostatic shaft for the second hydraulic unit. An auxiliary shaft can be coupled by a gear to a fixed gear operatively connected to a shaft of the power splitting device.
US08608605B2 Transmission apparatus for a tractor
A transmission apparatus for a tractor is operable to transmit a forward drive force in a wide speed changing range to the traveling device and which is operable also to transmit a reverse drive force to the traveling device. A planetary transmission section is configured to output the forward drive force in whichever case a hydrostatic stepless speed changing section is speed-changed to a forward rotation speed change state or a reverse rotation speed change state. A low speed transmission clutch couples a low speed side speed changing gear to a counter shaft to be rotatable therewith. A high speed transmission clutch couples a high speed side speed changing gear to the counter shaft to be rotatable therewith. A reverse transmission clutch couples a reverse transmission gear to an output shaft to be rotatable therewith.
US08608604B1 Torque divider and torque converter with lockup clutch
A torque converter and torque divider includes a prime mover input and a torque converter. The torque converter and torque divider further includes a torque divider configured to receive the prime mover input and divide the prime mover input torque into at least a planetary system input torque and a second torque. A planetary gear system is configured to receive the planetary system input torque. The torque converter and torque divider further includes a lockup clutch configured to lock rotating components of at least one of the torque converter and the torque divider and further includes a torque output.
US08608603B2 Belt drive system
[Purpose] A belt drive system, in which a drive belt 20 is wrapped between a drive pulley 1 drivingly connected to a drive source 11 and a driven pulley 2 connected to an driven unit 12 via a joint 32 provided to stop torque transmission when receiving a load equal to or over a predetermined value and torque is transmitted via the drive belt 20 from the drive pulley 1 to the driven pulley 2, ensures that when the driven unit 12 malfunctions, the joint 32 stops the torque transmission without unnecessarily increasing the coefficient of friction against the driven pulley 2 or the belt tension.[Solution] The belt drive system is configured so that when a slip corresponding to the load on the joint 32 equal to or over the predetermined value occurs between the drive belt 20 and the driven pulley 2, the coefficient of friction between the drive belt 20 and the driven pulley 2 becomes higher than that before the slip occurs.
US08608600B2 Recreational object
A recreational object comprises a hollow spherical member comprising a center and a plurality of apertures. A plurality of hollow arm members is configured to be joined to the spherical member at the apertures in which the arms joined to the spherical member are balanced about the center. The arm members each comprise a channel for enabling air passage through the arm and into the spherical member in which the air passage affects a flight speed and a rotational speed of the recreational object passing through air.
US08608597B2 Hockey stick
A blade for a hockey stick which can readily absorb impact from the puck, and can allow the user to feel the puck on the blade in contrast to conventional carbon fiber blades. The blade can include a blade member integrally formed of composite material having discontinuous fibers bonded within thermosetting resin. The blade member can have a blade periphery surrounding a central blade region. The central blade region can have a plurality of openings arranged in a pattern to form series of elongate criss crossing ribs that extend between and connect different sides of the blade periphery to each other. The fibers in the blade periphery can be in a generally jumbled orientation, and the fibers in the central blade region can be positioned within the ribs in a manner wherein each rib contains a plurality of fibers that substantially extend in said each rib's elongate direction.
US08608594B2 Golf ball
A first golf ball 2 includes a core 4, a mid-layer 6, and a cover 8. The core 4 includes a center 10 and an envelope layer 12. The mid-layer 6 includes a metal ion source (C) that can neutralize an ionomer resin. The mid-layer 6 has a melt flow rate (at 190° C. and 2.16 kg) of 4 g/10 minute or greater. The difference (H3-H1) between the JIS-C hardness H3 of the cover 8 and the JIS-C central hardness H1 of the center 10 is equal to or greater than 45. A second golf ball 22 includes a core 24, a mid-layer 28, and a cover 30. The mid-layer 28 has a melt flow rate (at 190° C. and 2.16 kg) of 4 g/10 minute or greater. Preferably, the mid-layer 28 includes a high melt viscosity resin (A), a low melt viscosity ionomer resin (B), and a metal ion source (C1).
US08608593B2 Golf ball
A golf ball 2 includes a core 4 and a cover 6 positioned outside the core 4. The cover 6 has a thickness of 0.2 mm or greater and 1.0 mm or less. The cover 6 is formed by injecting a resin composition from an injection molding machine into a mold. The product (M*V*T) of: a melt fluidity M (g/10 min) of the resin composition, which is measured at 190° C.; an injection rate V (cm3/sec) of the injection molding machine; and an injection time T (sec) of the injection molding machine, is equal to or greater than 500 and equal to or less than 1000. Preferably, in the golf ball 2, the melt fluidity M of the resin composition is equal to or greater than 15 g/10 min and equal to or less than 100 g/10 min.
US08608592B2 Coated golf club head/component
A golf club component, such as a golf club head and/or a golf club shaft, can comprise a golf club component substrate having an outer layer of titanium carbide, typically comprising at least forty percent (40%) carbon content. Alternatively, a golf club component can comprise a golf club component substrate, at least a portion of which is enveloped by a first coating layer of, for example, electroplated nickel, a second coating layer of, for example, electroplated chromium or palladium, and a third coating layer of titanium carbide applied by physical vapor deposition. The titanium carbide layer is durable and can provide the golf club component with a desired aesthetic appearance, such as a black color. Additionally, the golf club component can be coated with a fourth coating layer, such as a layer comprising a sealant or clear coat material.
US08608590B2 Engineered residual stress in golf clubs
A method of manufacturing a driver, or other types of golf club, includes inducing residual compressive stress by high intensity laser shock peening to form an array of laser shock peened impact zones on the club face. Laser pulses having irradiance greater than 4 GW/cm2, with spot size greater than 4 mm2 are used, including a pulse with on the order of 16 ns, with spot size greater than 9 mm2. Residual compressive stress of more than 400 MPa penetrating with a depth of more than 0.2 mm are imparted, without increased hardening in or damage to the face of the club. Laser shock peening a pattern that covers an interior area leaves the perimeter unpeened, inducing a stress gradient between interior area and the perimeter of the club face. Multiple layers of arrays of laser shock impact zones are applied on the club. The technology is readily applied to assembled club heads.
US08608588B2 Putter head
A putter head has a moment of inertia that can be adjusted easily by the golfer himself or herself. A putter head includes a body member having a face surface for hitting a ball and a back member turnably installed at the body member. The back member includes a plurality of movable parts, and the movable parts are turnably fixed to the body part. The movable part is turnably installed with one screw only.
US08608585B2 Golf club head or other ball striking device having a reinforced or localized stiffened face portion
A ball striking device, such as a golf club head, has a head that includes a face configured for striking a ball and a body connected to the face. A brace extends from an inner surface of the body or from a perimeter weight system to a contact point on the rear surface of the face. This brace may extend from the sole or a sole oriented perimeter weight member to the rear surface of the face. The brace applies force to the face (at least when the face is flexed by a threshold amount) such that the area of the face surrounding the contact point has less flexibility relative to other areas of the face located away from the contact point. The brace and club head may include structures that allow one to control and customize the force applied to the face.
US08608583B2 Golf club and ball performance monitor having an ultrasonic trigger
An ultrasonic trigger for a golf equipment performance monitor is described. In a preferred embodiment, the ultrasonic trigger comprises at least one emitter and receiver. The emitters periodically generate sound waves at an ultrasonic frequency. The sound waves are targeted towards an object or objects within a target area. The sound waves are reflected by the objects within the target area, and are detected by at least one receiver. The receiver may be connected to a computational device to determine the position and/or velocity of the objects within the field of view.
US08608582B2 Rocking play device
This Invention is provided with a pair of strut 120 vertically arranged by the base substrate, a pair of swing member 131, a motor 133, and an arm provided to a rotating shaft of the motor. A pair of swing member 131 is swingably connected to an upper part of the strut 120, a guidance shaft couples each one end neighborhood of the pair of struts. Also a motor 133 is attached to the upper part of the struts 120 similarly, the arm 134 provided to the motor 133 is connected to other end neighborhood of one of swing member 131 among the pair of swing members 131, And, if the rotating shaft of the motor rotates, the other end neighborhood connected with the arm 134 is eccentric rotated, causing swing of the pair of swing member 131.
US08608579B2 Ring rivet
An assembly for transferring torque including a first component having first wall portions, a second component having second wall portions, wherein the first wall portions extend radially from the first component toward the second component, the second wall portions extend radially from the second component toward the first component, the first wall portions are axially aligned with the second wall portions, and a clearance is formed between the first and second wall portions, and a ring rivet having a connecting portion inserted into the clearance and deformed for creating at least one head for axially locking the first component and the second component together, and wherein deforming the connecting portion fills the clearance for rotationally locking the first component and second component together for enabling a transfer of torque between the first component and the second component.
US08608576B2 Lens accessory for video game sensor device
A lens accessory for a video game sensor device and a method of adjusting a sensing distance of a video game sensor device. A lens accessory for a video game sensor device includes a first lens configured to cover an infrared light emitter of the video game sensor device, a second lens configured to cover an infrared light receiver of the video game sensor device, and a body portion coupling the first lens and the second lens together, the body portion being removably attachable to the video game sensor device, and the first lens and the second lens having a magnification for adjusting a sensing distance of the video game sensor device.
US08608573B2 Electronic trading card and game system
A trading card, a game system and method for interactive game system is disclosed. The trading card includes a substrate and a personality module configured to store one or more attributes of the trading card. The game system includes at least a first trading card and a second trading card. The first trading card and the second trading card include a substrate, a processing engine and a wireless interface configured to detect the presence of the other trading card. The first trading card sends a message to impact the second trading card. A method for interactive game system using first trading card and second trading card is also disclosed.
US08608568B2 Monitoring wagering game machines in a network
Methods and apparatus for monitoring wagering game machines in a network are described herein. In one embodiment, a method for monitoring wagering game machines in a network includes receiving, in a wagering game machine, a wager associated with a wagering game. The method can also include receiving status information associated with a peripheral device or other component of the wagering game machine and transmitting diagnostic information indicating whether the peripheral device or other component needs service, wherein the diagnostic information is based at least in part on the status information.
US08608562B1 Method and system for automatically managing a content approval process for use in in-game advertising
A method for approving data wherein a request for approval of advertising content for being impressed upon video game players within a known advertising spot within a known video game is provided. Based on the advertising spot and the video game a system determines at least a party for approving of the advertising content. Then, the system automatically transmits a message to the at least a party requesting their approval of the advertising content for being impressed upon video game players within the known advertising spot within the known video game.
US08608561B2 Computer-readable storage medium having object control program stored therein and object control apparatus
When a game apparatus detects a double-touch in an area other than an area where an enemy character is displayed, the game apparatus causes a player character to perform a forward roll motion. On the other hand, when the game apparatus detects a touch operation onto the enemy character, a prohibition area is provided at a position of the enemy character. When the game apparatus detects a touch onto the prohibition area, even if the touch operation is the double-touch, the game apparatus prohibits the player character from performing the forward roll motion and causes the player character to attack the enemy character.
US08608560B1 Non-deterministic animations with predetermined result
A method, system, and computer readable storage medium to display sports and other animations using a reduced amount of assets. Pregenerated clips can be stored and combined to create complete animations with predetermined outcomes. The same predetermined outcome can have numerous animations which all result in the same predetermined outcome, all while using a reduced amount of stored assets.
US08608555B2 Jackpot controller and a method of providing a jackpot for a gaming machine
The invention generally relates to gaming machines and methods implemented with use of a gaming machine. A prize awarded on a gaming device is awarded by obtaining a turnover value for at least one gaming device over a period of time, calculating a probability value based on the turnover value and using the probability value to determine whether the prize is to be awarded. In some implementations there may be two prizes that are awarded with different probabilities when the gaming machine system is in different configurations.
US08608554B2 Delayed bonus win determination
Embodiments of the present invention are directed to gaming devices having a delayed bonus win determination and methods of operating gaming systems and gaming devices to provide delayed bonus win determinations. Here, contributions to a linked jackpot may be separated from the chance to win the linked jackpot, where the chance to win the linked jackpot can be stored and used at a later time.
US08608549B2 Gaming machine providing bet region with new payout rate in roulette game
The range of game strategies for a player in a roulette game is broadened by providing a bet region corresponding to a new bet rate. A CPU displays a plurality of bet regions, as well as displays a third bet region corresponding to a third numerical range that is smaller than a first numerical range corresponding to a first bet range among a plurality of bet regions, and that is larger than a second numerical range corresponding to a second bet region among the plurality of bet regions. Next, a bet is accepted for a bet region thus displayed, and in a case where it is determined that an award is to be granted for the bet region thus accepted, payout data corresponding to the bet region is extracted from ROM, and the award according to the payout data thus extracted is granted.
US08608548B2 Intelligent wagering token and wagering token tracking techniques
Wireless communications among devices in a wager-based gaming environment are provided, including between a number of RFID-enabled player tracking cards (or “smart cards”) and an electronic wagering token. The electronic wagering token periodically samples and stores updated information received from the smart cards; periodically acquires updated wagering token ownership information relating to an identity of a current owner of the wagering token, based on the sampled and stored updated information; stores, in a memory of the wagering token, at least a portion of the updated token ownership information; and provides, to at least one external device, wireless access to a first selected portion of the updated token ownership information stored in the memory.
US08608545B2 Gaming system, gaming device, and method providing a game including a cascading symbols feature causing one or more repositioned symbols to be wild symbols
The present disclosure provides a gaming system, device, and method providing a cascading symbols feature. For a play of a game, the system generates and displays one of a plurality of symbols at each of a plurality of symbol display areas, and determines any awards associated with the displayed symbols. If a triggering event occurs, the system determines a set of the displayed symbols. For each displayed symbol of the determined set, the system removes that displayed symbol, resulting in an empty symbol display area. For each empty symbol display area, the system repositions one of the other displayed symbols, which creates a second empty symbol display area, and causes at least one of any repositioned symbols to be a wild symbol. The system generates and displays one of the symbols at each of any second empty symbol display areas, and determines any additional awards associated with the displayed symbols.
US08608543B2 Gaming system and method for providing an incremental wagering game
Various embodiments of the present disclosure provide a gaming device which enables a player to purchase the game in stages or increments. The gaming device enables the player to place a first wager for a play of the game. After receiving the first wager, the gaming device randomly generates and displays a first outcome. The gaming device evaluates the displayed first outcome to determine whether the displayed outcome includes any winning symbol combinations. The gaming device provides the player with any awards associated with any determined winning symbol combinations. After providing the player with any awards based on the displayed first outcome, the gaming device offers the player the opportunity to make a second wager for the play of the game. If the second wager is placed, the gaming device generates and displays the second outcome, while the first outcome remains displayed. The gaming device evaluates the displayed second outcome in combination with the displayed first outcome to determine whether any winning symbol combinations are displayed. The gaming device provides the player with any awards associated with any displayed winning symbol combinations. If the player chooses not to make the second wager for the play of the game, the play of the game terminates. In this manner, the present disclosure enables a player to decide when to continue building on an outcome that is good and when to stop the play of the game.
US08608542B2 Gaming system, gaming device and method providing competitive wagering games
The gaming system and method disclosed herein provides a player with an opportunity to compete against an opponent (either a virtual opponent or a human opponent). In one embodiment, the gaming system and method provide a competition game that operates concurrently with a wagering game. In one embodiment, the competition game includes a turn-based video game which enables a player to compete against an opponent. Different generated symbol combinations for the wagering game represent different game actions or sequences for the competition game. That is, the symbols or symbol combinations generated in the wager game determine which game actions or sequences the gaming system causes to occur for the competition game. Based on such displayed game actions and sequences, the disclosed gaming system and method determines whether the player or the opponent wins that competition for the competition game.
US08608541B2 Gaming device and method of use
A gaming device including a game apparatus configured to allow a player to play a game including moveable prize objects is disclosed. The gaming device may also include a prize object holder configured to hold the prize objects where the prize objects are allowed to move within the prize object holder. A controller may be in communication with the game apparatus. The controller may be configured to determine a game outcome and to move the prize object holder to display the game outcome to the player. In another embodiment, a dynamic prize object which is distinguishable from all other prize objects may be included among the moveable prize objects where the dynamic prize object may be used to convey special prizes to the player.
US08608540B2 Multiple-game gaming machine
A gaming machine includes a gaming console. A display is mounted in the gaming console for displaying a wagering game and its result. A controller controls operation of the game, the controller displaying the result of a first game on the display, making payment of a prize if the first game has a prize winning result and, thereafter, irrespective of the result of the first game, varying a result displayed on the display without requiring any additional wager by a player whether before or after completion of the first game.
US08608536B2 Bankruptcy in a virtual environment
A virtual environment in which characters are able to engage in a variety of financial transactions is provided. Characters who are unable to fulfill their financial obligations may enter into bankruptcy. Bankruptcy contracts may identify various conditions which must be fulfilled by the character in order to get out of bankruptcy. While in bankruptcy, the player's avatar or avatar's may be altered to indicate to the player and/or others that the character represented by the avatar is in bankruptcy.
US08608534B1 Rolled secondary cut off in air distribution system of a combine harvester
A combine harvester has a threshing mechanism for threshing grain and cleaning apparatus for removing chaff from the threshed grain. The threshing mechanism includes a rotor and a plurality of concaves and the cleaning apparatus includes and upper chaffer and a lower sieve. A blower provides cleaning air to the combine harvester. The blower is situated in a blower housing having a first cut off plate separating high-velocity air coming from the blower and directing a first portion of the high-velocity air to a lower duct that provides an airstream to the upper chaffer and lower sieve. The blower housing also has a second cut off plate directing a second portion of the high-velocity air to an upper duct that provides an airstream under the concaves. A leading portion of the second cut off plate contains a rolled edge along the width of the upper duct.
US08608532B2 Climate control duct architecture for a vehicle
A climate control duct architecture having partitions to provide effective distribution of air immediately as it exits the HVAC. By strategic positioning and configuring of the partitions the duct architecture may be tuned to provide maximum console airflow and desired system airflow distribution with a minimum amount of interference to the airflow due to turbulence.
US08608531B1 Arrow preparation system
An arrow preparation system preferably includes a lengthwise base, at least two arrow supports and a grinding member. The lengthwise base preferably includes a pair opposing rails for slidably retaining the at least two arrow supports and the grinding member. Each arrow support preferably includes a support slidable base, a pair of roller bearings, an anchor pin and a knurled nut. The knurled nut is secured to anchor pin and threadably retained in the support slidable base. The pair of roller bearings are rotatably retained on a top of the support slidable base to support an arrow shaft. The grinding member preferably includes a slidable grinding base, the anchor pin and the knurled nut. The slidable grinding base includes a vertical grinding face. A piece of self-sticking sandpaper is applied to the vertical grinding face. The knurled nut and anchor pin and threadably retained in the slidable grinding base.
US08608530B2 Insertion tool for a machine tool
The present invention is directed to an insertion tool (12) for a machine tool that has a hub (16) with at least one opening (42, 80) for insertion of a fastening means (40, 84), via which the hub (16) is clampable on a driving flange (22) of the machine tool connected to a drive shaft, the opening (42, 80) including a retaining region (54) and a releasing region (56), the releasing region (56) including a stop (66, 88) for limiting a release motion of the fastening means (40, 84).It is provided that the opening (42, 80) adjacent to the stop (66, 88) has a convex section (76, 90).
US08608528B2 Toy vehicle track play set
A vehicle track play set includes a base, a plate coupled to and extending upwardly from the base, and first and second tracks extending along the plate toward the base. The first track includes a first curved portion extending outwardly from a first surface of the plate and a second curved portion extending outwardly from an opposite second surface of the plate. The first track extends through a first opening in the plate between the first and second curved portions. The second track includes a third curved portion extending outwardly from the second surface and a fourth curved portion extending outwardly from the first surface. The second track extends through a second opening in the plate between the third and fourth curved portions.
US08608527B2 Wall mounted toy track set
A track set and a plurality of wall mounts is disclosed herein, each of the plurality of wall mounts having: a planar member; a mount member configured to be snap fittingly engaged into the planar member; wherein the mount member is configured to releasably engage a front surface of the planar member and wherein the front surface of planar member further comprises a ledge portion that is configured to engage a bottom portion of the mount member and a1 feature that is configured to engage an upper portion of the mount member. The track set having a first track segment configured to engage at least one of the plurality of wall mounts and direct an object in a first direction generally down the first track segment; and a U-turn device configured to receive the object from the first track segment and redirect the object it in a direction substantially opposite to the first direction down a second track segment. The second track segment being configured to engage at least another one of the plurality of wall mounts.
US08608521B1 Mission-based systems and methods for operating hybrid propulsion systems for marine vessels
Systems and methods of operating a marine propulsion system utilize an internal combustion engine and an electric motor that is powered by a battery, wherein the internal combustion engine and the electric motor each selectively power a marine propulsor to propel a marine vessel. A control circuit is operated to control operation of the system according to a plurality of modes including at least an electric mode wherein the electric motor powers the marine propulsor and a hybrid mode wherein the internal combustion engine powers the marine propulsor and provides power for recharging the battery. An operator-desired future performance capability of the hybrid marine propulsion system is input to the control circuit, which selects and executes the plurality of modes so as to provide the operator-desired desired future performance capability.
US08608518B2 Wire-grasping structure for terminal block
A wire-grasping structure for a terminal block includes a seat part, a fixing piece, a cover part, a fastening piece, a screw and a spring. The seat part has a transverse opening. The fixing piece is received in a lower accommodating recess of the seat part to slide in the seat part vertically. The cover part covers the seat part. The fastening piece is sandwiched between the cover part and the seat part. The screw is vertically received in an upper accommodating recess of the cover part and aligned with the through hole of the fastening piece and the threaded hole of the fixing piece. The spring is vertically received in the upper accommodating recess of the cover part and has two ends abutting against the fastening piece and the screw. The wire-grasping structure has good wire-grasping reliability and good applicability and is convenient to use.
US08608517B2 Wedge connector assemblies and methods and connections including same
A wedge connector assembly for forming an electrical connection with an elongate electrical conductor includes a resilient spring member and a cam wedge member. The spring member defines a spring member channel. The spring member channel has a spring member channel axis and is configured to receive the electrical conductor such that the electrical conductor extends along the spring member channel axis. The cam wedge member is mounted on the spring member such that the cam wedge member is rotatable relative to the spring member about a pivot axis to a locking position wherein the cam wedge member captures the electrical conductor in the spring member channel and elastically deflects the spring member.
US08608502B2 Connection mechanism
A connection mechanism between two components may use one or metallic pins that are magnetically extended when the components are engaged, and a sloped groove that retracts and unlocks the pins when the components are rotated. The components are locked in place by the pins during engagement. Disengagement may be performed by rotating the two components with respect to each other. The connection mechanism may include one or more magnets mounted on either or both components. The magnets may be arranged to attract the components when the components are in the locking orientation and to repel the components when the components are rotated to an unlocked position. The connection mechanism may include electrical connections between the components.
US08608497B2 Card connector assembly with plug having first and second connector
A connector assembly for a modular device that connects to a host device, including a receptacle forming part of a host electronic device, and a connector plug mounted on one side of a modular electronic device, for use with two operational modes of the modular device, including a first connector for engagement with the receptacle in a first operational mode in which the modular device is connected with the host device, and a second connector for engagement with a cable external to the modular device in a second operational mode in which the modular device is not connected with the host device, the second connector being covered by the host device but not engaged therewith when the first connector is engaged with the receptacle, thus enabling the modular device to be used with a host or alternatively removed from the host and connected to a cable for external use.
US08608495B2 Power supply apparatus
A power supply includes first connecting board, a second connecting board and a conductive module. Three adapters are located on the first connecting board. The three adapters connect with power supply via three anodes and three cathodes. A connector is located on the second connecting board and configured to output power. The conductive module includes a first bus bar and a second bus bar. The first bus bar includes three input terminals and an output terminal. The second bus bard includes three input terminals and an output terminal The three input terminals of the first bus bar are electrically connected to the three anodes of the three adapters. The three input terminals of the second bus bar are electrically connected to the three cathodes of the three adapters. The output terminals of the first bus bar and the second bus bar are electrically connected to the second connecting board.
US08608490B2 Modular wiring system
A modular wiring system includes a junction box having a plurality of ports and a programmable wiring board carrying electrically conductive elements. A plurality of cable receiving connectors are each insertable into a corresponding one of the plurality of ports of the junction box and each provides electrical coupling between wires of a cable and the electrically conductive elements of the programmable wiring board. At least one electrical device receiving connector is coupled to the programmable wiring board. The at least one electrical device receiving connector releasably receives an electrical device and provides electrical coupling between the electrical device and the electrically conductive elements of the programmable wiring board.
US08608489B2 AC adaptor and method for fabricating the same
An AC adaptor is disclosed, a plug extends in a first direction so as to penetrate a part of a case. A circuit board is disposed within the case. A contact terminal is disposed on the circuit board, and elastically contacts an end portion of the plug (without being soldered thereon). A first regulator is disposed within the case and regulates a position of the circuit board in a second direction orthogonal to the first direction. A second regulator is disposed within the case and regulates a position of the circuit board in a third direction orthogonal to the first direction and the second direction.
US08608488B2 Conductive terminal with a central bulged portion configured for swinging relative to a base material
A portable electronic device includes a base material, a fixing-cover and conductive terminals. The base material has first contact-pads and second contact-pads. The fixing-cover is disposed on a first surface and exposes the first contact-pads. The fixing-cover has a clamp portion. The terminals are disposed on the second contact-pads, wherein a first end of each the terminal extends out of the fixing-cover. A second end leans against the fixing-cover. A central portion is located between the two ends, wherein the bottom of the central portion bulges and contacts the corresponding second contact-pad, and the two ends can swing relatively to the base material around the bottom of the central portion as the pivot. The central portion has a positioning portion formed in direction facing the opening and the positioning portion is embedded in the opening.
US08608484B2 Dynamic anthropomorphic cardiovascular phantom
A cardiovascular flow system includes: a cardiovascular model system, a pump system in fluid connection with the cardiovascular model system, and an ECG simulator in communicative connection with the pump system. The ECG simulator system is adapted to create and transmit a simulated ECG signal. The ECG simulator system uses a signal received from the pump system to adjust the simulated ECG signal transmitted from the ECG simulator system. The cardiovascular flow system further includes an injection port adapted to be placed in fluid connection with an injector to inject at least one fluid into the system.
US08608482B2 System and related method for instructing practitioners relative to appropriate magnitude of applied pressure for dental procedures
System and method for teaching a dental practitioner an appropriate pressure to apply during a dental procedure. The system includes a dental tool for use in a dental procedure and a substrate including a coating of a removable scratch-off material. The scratch-off material is adhered to the substrate so as to have an adherence strength that is specifically configured so that the scratch-off material coating is removable from the substrate by manipulating the dental tool against the scratch-off material coating upon application of a minimum threshold pressure that is substantially equal to that to be applied during a selected actual dental procedure. In this manner, an inexperienced practitioner is able to learn the appropriate magnitude of pressure to be applied during a procedure (e.g., application and burnishing of a hemostatic composition into bleeding soft tissue) in a non-threatening environment without having to actually work on a live, bleeding patient.
US08608475B2 Motion simulator and method
A motion simulator for transmitting motion with respect to a floor as a function of motion signals associated to a video output. The motion simulator comprises a seating portion for accommodating a viewer viewing the video output. Actuators each have a housing and an output shaft interrelated by a degree of freedom. Each of the actuators has a motor connected to the seating portion for displacing the housing with respect to the output shaft along the degree of freedom as a function of actuation from the actuators in relation to the motion signals. The housing of each of the actuators is secured to the seating portion. The output shaft of each of the actuators comprises a leg supporting the motion simulator on the floor, whereby the seating portion is movable as a function of actuation from the actuators.
US08608474B2 Recoil impulse generator for a weapon simulator
The invention relates to a recoil impulse generator for a weapon simulator comprising a force storage element and an impulse mass that can be moved and that is moved from a stressed to an unstressed position with a triggering element is actuated in order to simulate a recoil impulse. The recoil impulse generator comprises a drive that drives a spindle uninterruptedly during a shot sequence simulating several shots; a coupling that is connected to the impulse mass and to the force storage element and that engages in the spindle in an engaged state and that is moved along the spindle by means of rotation of the spindle in order to bring the impulse mass into the stressed position again the force applied by the force storage element; a disengaging means that switches the coupling to a disengaged state when the impulse mass has reached the stressed position; and an engaging means that switches the coupling to the engaged state when the impulse mass has reached the unstressed position.
US08608470B2 Apparatus for removing resin molded product
A holding member can be made to move up and down with long strokes by means of short vertical strokes so that the overall arrangement can be downsized and lightweight. Additionally, the holding member can be held to a constant attitude and the overall arrangement can be simplified to reduce the cost. A swing arm is adapted to be swung between the metal mold of a resin molding machine and the outside of the resin molding machine by means of a rotary shaft rotating in response to a vertical motion of an elevating body relative to a vertical frame and, at the same time, a fitting member is adapted to be driven to rotate in response to the swinging motion of the swing arm in order to control the attitude of a vertical arm so as to make its axial line aligned with the vertical direction.
US08608467B2 Device and method for twisting elongated dough strips
The present invention relates to a device for twisting elongated dough strips, comprising at least one pair of grippers, each arranged for gripping and respectively releasing one short side of a dough strip, and means for mutually rotating the grippers around an axis of rotation. In an embodiment, the device comprises a first conveyor for supplying dough strips oriented with their long sides perpendicular to the direction of conveyance wherein the width of the first conveyor is chosen smaller than the long sides of the dough strips so that the short sides of a dough strip protrude from the first conveyor, and a second conveyor for carrying off the twisted dough strips. The invention further provides a method for twisting an elongated dough strip.
US08608466B2 Blow mold unit and blow molding apparatus using the same
A blow mold unit includes a first and a second blow cavity split mold, and a plurality of raised-bottom molds. The blow mold unit also includes a first and a second securing plates on which the first and the second blow cavity split mold are secured, a plurality of first pressure-receiving plates respectively secured on the first and the second securing plates, a third securing plate disposed between the first and the second securing plates, the plurality of raised-bottom molds secured on the third securing plate, a plurality of shafts suspended from the third securing plate, and a plurality of second pressure-receiving plates secured on the first and the second securing plates at a position below the third securing plate.
US08608464B2 Check valve
Check valve with a valve housing, on which is formed a valve seat. The valve seat is designed as an oblique face with respect to a flow direction. A shut-off element has at least one sheet-like shut-off tab which is composed of an elastically deformable material and which, in a shut-off position, bears against the valve seat and, in an opening position, is lifted off from the valve seat, in order to allow the passage of fluid. An abutment element is arranged on that side of the shut-off tab which faces away from the valve seat. The shut-off tab can abut against the abutment element in order to limit the amount by which the shut-off tab is lifted off from the valve seat.
US08608457B2 Device with a drum with a drive motor mounted therein
A device for driving a drum (1) about the axis thereof, including a motor (2) which is mounted at least partially inside the drum (1) and a transmission (7) disposed between the motor (2) and the drum (1), characterized in that it further includes a device (10) enabling a forced current of cooling air to be created in a space (13,14) between the motor (2) and an inner wall of the drum (1).
US08608454B2 Combined pump housing for several rated quantities
In a swash-plate type hydrostatic piston engine, a drive unit (10) and a swash plate (17) are received by a pot-shaped housing (1b). According to the invention, the pot-shaped housing (1b) is configured such that it is able to receive drive units (10a, 10b) of at least two rated quantities of a specific product series of the hydrostatic piston engine.
US08608452B2 Variable coolant pump
A variable coolant pump for a cooling circuit of an internal combustion engine that has a pump housing in which is mounted a hollow shaft that is driveable by a pulley. At one end of the hollow shaft an impeller is fastened which has vanes projecting into an inlet chamber and which is firmly connected via axial bridges to a cover disc. Through rotation of the impeller together with the cover disc, water can be sucked into the inlet chamber via an inlet connection piece of the pump housing and conveyed by the vanes into an annular passage of the pump housing. A guide disc with a contour corresponding to the impeller is further arranged between impeller and cover disc. The guide disc is guided by the axial bridges and can be displaced axially via a positioning unit by a piston located inside the hollow shaft.
US08608451B2 Liquid ring vacuum pump for degassing molten plastic
A liquid ring vacuum pump for degassing molten plastic has an inlet where gases are drawn in and an outlet through which gases are blown out. A closed circulation path for the compression fluid holds a replaceable filter insert for filtering coarse contaminants out of the compression liquid, a precondensation unit upstream of the pump inlet for filtering fine contaminants out of the compression liquid, and only one continuously operating fine or ultrafine filter in the closed circulation path. The closed circulation path is closed even when the fine filter or ultrafine filter is replaced. A controller connected to the continuously operating filter directs replacement of the filter element as a function of degree of contamination, filtering time, pressure conditions, or flow velocity conditions at the filter.
US08608449B2 Support for a large vertical axis wind turbine
A support for a large vertical axis wind turbine including a tower frame, a platform, a vertical central axis, and a vertical axis windmill including a plurality of blades and supporting arms. The platform is disposed on the tower frame for installing and fixing a generator. The vertical central axis and the vertical axis windmill are supported by the tower frame. The tower frame is a truss structure and includes at least three sub-tower frames which are in parallel with each other and form a regular polygon from top view. The sub-tower frames are hollow tubes. The ratio of a diameter of the vertical axis windmill to a distance between two adjacent sub-tower frames is between 2.5 and 6. The ratio of the diameter of the vertical axis windmill to a height of the tower frame is between 3 and 0.5.
US08608438B2 Mounting device for fan and fan module with the same
A mounting device for a fan includes a first mounting frame and a second mounting frame adjustably mounted to the first mounting frame according to the height of a fan, to sandwich the fan between the first and second mounting frames.
US08608436B2 Tapered collet connection of rotor components
A connection between an annular sleeve on a gas turbine engine first rotor component includes an annular tapered conical slot extending axially inwardly into the sleeve from an annular opening and tapers axially into the sleeve from the opening. An annular rim of a second rotor component is received within the conical slot and includes a rim inner conical surface mating with and contacting a sleeve inner conical surface in part bounding the conical slot. A sleeve cylindrical outer surface in part bounds the conical slot in the sleeve and a rim outer cylindrical surface on the annular rim contacts the sleeve cylindrical outer surface. An annular lip may extend radially inwardly from the sleeve and sleeve inner conical surface at the annular opening to the conical slot. The connection may be used between a first stage disk and an interstage seal.
US08608435B2 Turbo engine
A turbomachine, especially a gas turbine, includes a rotor having rotating blades and a stator having a housing and guide blades. The rotating blades form at least one rotating blade ring, which at one radially outward lying end adjoins an inner ring or casing ring of the housing, thereby defining a gap therebetween. The casing ring is connected to a support ring via curved walls, which together with the casing ring and the support ring bound a cavity and form a bellowslike structure. By changing the pressure prevailing in the cavity of the respective bellowslike structure, the gap between the casing ring and the radially outward lying ends of the respective rotating blade ring can be pneumatically adjusted.
US08608433B2 Turbine having variable throat
The invention relates to a turbine (1) for a turbocharger, comprising a turbine wheel (2) and a turbine housing (5) forming a passage (6) for guiding a fluid flow to the turbine wheel (2), said passage (6) comprising a variable throat providing a throat area (8) as a smallest cross section of the fluid flow, wherein the variable throat is always defined by a annular member (7) surrounding the turbine wheel (2) and being movable in the axial direction of the turbine wheel (2).
US08608430B1 Turbine vane with near wall multiple impingement cooling
A turbine vane with a low flow near wall multiple impingement cooling circuit in which a thin thermal skin is bonded over a main support spar that together forms a series of chordwise extending collection and impingement chambers extending from the leading edge region to the trailing edge region of the airfoil. Cooling air from a cooling air supply cavity flows through feed holes and into a first one of the collection chambers located in the leading edge region, and then through impingement cooling holes for backside impingement cooling of the airfoil wall. the series of collection and impingement is repeated along the airfoil wall until the spent impingement air is discharged through exit holes on both sides of the trailing edge region.
US08608429B2 System and method for enhanced turbine wake mixing via fluidic-generated vortices
A high pressure turbine (HPT) blade includes a substantially arcuate trailing edge including one or more fluid injection elements disposed therein. Each fluid injection element injects a fluid such as air into a desired trailing edge region of the HPT blade or vane to enhance mixing out of the wakes generated via the HPT blade or vane. The enhanced mixing out reduces HPT/LPT interaction losses and/or the axial gap between the HPT and LPT components in a gas turbine engine. The interaction losses include unsteady thermal wake segregation effects that lead to unexpected heat-up of endwalls (planforms and blade/vane-tips) of downstream blades/vanes, and further include aerodynamic losses, both transonic and subsonic.
US08608426B2 System and methodology for wind compression
A wind compressor system having one or more wind turbines and a plurality of wind compressors located proximate the one or more wind turbines. The wind compressors optimize the energy created by the wind turbines by redirecting and converging the wind from the wind compressor to the wind turbines. Each of the wind compressors comprises an obstruction having a size and shape adapted to converge the wind currents by means of a Venturi effect toward the one or more turbines thereby increasing the velocity and force of the wind hitting the wind turbine. A plurality of transporters coupled to the wind compressors. The transporters configured to move at least one wind compressors to a location that maximizes the force of the wind encountered by the turbine.
US08608422B2 Particle sticking prevention apparatus and plasma processing apparatus
In order to prevent particles within a unit from sticking to a substrate in a substrate processing process, an ion generator charges the particles. At the same time, a direct current voltage of the same polarity as the charged polarity of the particles is applied from a direct current power source to the substrate. In order to prevent generation of particles when producing gas plasma, a high-frequency voltage is applied to the upper and lower electrodes at multiple stages to produce plasma. In other words, at a first step, a minimum high-frequency voltage at which plasma can be ignited is applied to the upper and lower electrodes, thereby producing a minimum plasma. Thereafter, the applied voltage is increased in stages to produce predetermined plasma.
US08608418B2 Bonding washer
A bonding washer for making electrical connection between two metal pieces that are to be mechanically fastened together. The washer, to be interposed between the two metal pieces, may be constructed so as to fasten to one of the pieces before the two pieces are joined. Teeth on the washer, positioned at right angles to the plane of the washer, are forced into each of the two metal pieces when the fastener is tightened, making electrical connection between the two metal pieces.
US08608417B2 Dual action disposable clamp
Disclosed is a clamp that includes a mechanical fastener, an expander including a bulbing portion and a shank wherein the bulbing portion of the expander forms a flange by movement of the mechanical fastener without applying an initial clamping force. After formation, the flange is then drawn into a clamping position by continued movement of the mechanical fastener. Also disclosed is a method of using the disclosed clamp.
US08608412B2 Feed mechanism for a boring bar
A boring bar feed mechanism comprising a boring bar and a rotation mechanism for rotating the boring bar, a feed shaft, a feed coupling the feed shaft with the boring bar for axially translating the boring bar, and the boring bar is rotationally mounted with respect to but axially fixed to a second end of the feed coupler. A cam is rotationally fixed to the boring bar for rotating with the boring bar and a cam follower interacts with the cam. A plunger housing is supported by an extension of the cam follower and the plunger housing accommodates at least one feed plunger. A converter gear is supported by the feed shaft and the feed plunger interacts with the converter gear to facilitate indexing of the converter gear. The plunger housing is pivotally supported by the extension of the cam follower to permit the plunger housing and the feed plunger to have a limited pivoted motion, relative to the cam follower, as the cam follower oscillates back and forth and indexes the feed shaft.
US08608409B2 Foundation pile driver
A pile driver for driving foundation piles, and having: a frame, in turn having a horizontal base, at least one upright extending upwards from the base, and a movable body which slides along the upright; a first lock device fitted to the horizontal base and which, in use, rigidly engages a connecting member of a foundation structure; a second lock device fitted to the movable body and which, in use, rigidly engages a shaft of a pile to be driven; and at least one hydraulic jack connected to the frame and to the movable body to move the movable body along the upright.
US08608406B2 Landing mechanism for lifted pipe reel
A reeled pipe storage reel with a large diameter hollow cylindrical shaft, reel shaft bearing support structures installed on the vessel, and a reel drive arrangement mounted on the vessel. The shaft across the width of the reel provides structural stiffness and consistent alignment of the bearings on each end of the shaft. Each end of the shaft extends beyond the reel and includes a section for connection to a lifting sling, a section for the machine bearing surface, and a section for absorbing initial contact with the vessel during installation. The reel shaft bearing support structures on the vessel include a fixed portion to match the bearing area of the reel shaft and a movable portion to absorb initial contact during installation of the reel. The reel drive arrangement is located on linkages so they can be manipulated in the plane of the reel flange for movement into engagement with the drive gear on the reel flange.
US08608404B2 Smart sustainable agricultural/aquacultural system and methods
An agricultural/aquacultural system for use with a plurality of growth reservoirs containing a fluid. The system involves a main control unit for receiving feedback and providing control, at least one pump control unit in electronic communication with the main control unit, and at least one gate control unit in electronic communication with the main control unit.
US08608403B2 Magnetic vibratory compactor
A machine comprising a vibratory compactor assembly having a cylindrical drum connected to the machine with an axle. The assembly has a shaft extending concentrically through the center of the cylindrical drum that has a first end and a second end. The shaft has an electromagnet between its first end and second end. The electromagnet can receive electric current to create a magnetic field that applies an attractive magnetic force between the shaft and the drum that pulls the shaft and at least a portion of the drum toward one another.
US08608402B2 Leveling blade, vibrating screed including the blade, and kit for assembling the same
A leveling blade mounts onto a support bracket of a vibrating screed, and a vibrating screed includes the same. The leveling blade has a substantially vertical portion for mounting onto the support bracket, as well as a substantially slanted portion and a substantially horizontal portion, which results in the leveling blade having a particular profile. The vibrating screed includes also a vibration-generating assembly, being operatively mounted onto the support bracket of the vibrating screed for imparting vibrations to the leveling blade via the support bracket so as to enable carrying out a surfacing of a substantially malleable material with the vibrating screed by passing the leveling blade provided with vibrations about the substantially malleable material. A kit is also provided for assembling such a vibrating screed.
US08608401B2 Modulated structural cell for supporting a tree root network
A modulated cell adapted to form a structural frame of said cells for supporting a load bearing feature of a roadway, pavement or walkway while at the same time providing a rooting area within the structural frame for a tree root network. The cell has a main body with vertical integral legs with a top plate having regions upon its upper skirting for a snap fit fastening arrangement for receiving the ends of said legs of a resting cell thereupon said top plate to mount one cell vertically upon another and the top plate has its peripheral edge an interlocking means for laterally joining together with adjacent cells so the modulated cells can be mounted vertically and laterally one upon the other and side by side.
US08608397B2 Dispensing applicator for fluids
A hand-held dispensing applicator comprising a source of fluid, a frangible applicator tip attached to the fluid source, and an absorbent member attached to the frangible applicator tip. When the frangible applicator tip is broken, fluid flows from the source to the absorbent member, whereby the fluid is applied and spread on a surface. Preferably, the frangible applicator tip comprises a support element permanently connected to the fluid source, a relatively rigid tongue element extending outwardly of the support element, and a frangible region therebetween. Preferably, the tongue element comprises ribs for reinforcing the tongue element to resist unintentional breaking of the frangible region. More preferably, the applicator tip comprises a semi-permeable or non-permeable cover disposed around the frangible region to control the speed and direction of the dispersion of the fluid in the absorbent member. Adaptive embodiments allow the generation of designs applicable to a particular medical purpose.
US08608396B2 Floor finish applicator
A floor finish applicator including a cart having wheels and a body member constructed and arranged to receive a source of floor finish. The floor finish applicator also includes a pump coupled to the cart and operable to deliver floor finish to a floor, a floor finish feed conduit in fluid communication between the pump and a container supporting floor finish, and a transmission assembly coupled to the cart. The floor finish feed conduit supplies floor finish to the pump. The transmission assembly includes an axle coupled to and driven by a wheel of the cart, a drive gear connected to the axle, a drive shaft having a driven gear for engaging the drive gear and driving the pump, and a hand-actuated spring-loaded clutch for selective engagement of the pump and the drive shaft with the axle.
US08608395B2 Floor finish applicator
A pull-behind floor finish applicator wherein a peristaltic pump is employed in conjunction with disposable conduit tubing obviate any clean up of the pump. This applicator is adaptable to receiving bag in the box floor finish, thus reducing cleaning time. The applicator employs a minimum number of disposable parts thus making it economical to produce. A mop is employed to apply floor finish to easily accessible areas in one instance, yet allows the mop to be used independently for application of floor finish to not so easily accessible areas.
US08608393B2 Capillary actuator deployment
A method for making an actuator includes forming a substantially planar actuator device of an electrically conductive material, the device incorporating an outer frame, a fixed frame attached to the outer frame, a moveable frame disposed parallel to the fixed frame, a motion control flexure coupling the moveable frame to the outer frame for coplanar, rectilinear movement relative to the outer frame and the fixed frame, an actuator incorporating a plurality of interdigitated teeth, a fixed portion of which is attached to the fixed frame and a moving portion of which is attached to the moveable frame, moving the moveable frame to a deployed position that is coplanar with, parallel to and spaced a selected distance apart from the fixed frame, and fixing the moveable frame at the deployed position for substantially rectilinear, perpendicular movement relative to the fixed frame.
US08608390B2 Optical communication module
To reduce a size of an optical communication module.

There is provided an optical communication module 1, which includes a photoelectric conversion element package 10 to which a photoelectric conversion element 12 of either one of a light emitting element and a light receiving element is fitted so as to face one side 11a of a resin base 11, and an optical fiber coupler 20 having a light transmission hole 20c for coupling with an optical fiber in cylindrical portions 20a and 20b and mounted on the one side 11a of the resin base 11, where the photoelectric conversion element 12 and the light transmission hole 20c formed in the optical fiber coupler 20 are assembled aligned with an optical axis K. In the photoelectric conversion element package 10, the photoelectric conversion element 12 is fitted to the other side 11b opposite to the one side 11a of the resin base 11, and the photoelectric conversion element 12 is arranged at the center of a hole 11c bored through between the one side 11a and the other side 11b, aligned with the optical axis K.
US08608388B2 Semiconductor device and connector
A semiconductor device of the present invention includes: a circuit substrate; an optical semiconductor element provided on the circuit substrate; and a sealing resin provided on the circuit substrate, with which the optical semiconductor element is sealed, the sealing resin having a cuboid shape or a cubic shape, the sealing resin having an outer shape having at least one cutout part, in a case where a single cutout part is formed, the cutout part being provided in an area other than a center area of a top surface of the sealing resin, in a case where a plurality of cutout parts are provided, the cutout parts are formed so as not to be symmetric with respect to the central point on the top surface. With this arrangement, it is possible to provide a semiconductor device which can secure prevention of a sealing resin from being, in an erroneous direction, fitted into a connector.
US08608386B2 Journal bearing design
The present disclosure relates to bearings, for example, an improved journal bearing. A bushing (44) for use with a journal bearing (40) includes: a cylindricarinterior defining an interior bearing surface (46); a longitudinal axis (45) and an internal diameter (ID); a groove region of the interior bearing surface (46) having a length H along the longitudinal axis; and a set of grooves (48) in the grooved region of the interior bearing surface (46), where N is the number of grooves in the set of grooves (48). Each groove is disposed at a helix angle (θ) offset from the longitudinal axis (45) of the bushing (44). The helix angle is approximately equivalent to the following equation: tangent (θ)=(π×ID)/(N×H).
US08608382B2 Static-pressure bearing apparatus and stage comprising static-pressure bearing apparatus
A static-pressure bearing apparatus that prevents vibrations, the apparatus including an orifice and a vent groove, such that a laminar-flow status may be maintained in the entire region of the routes of the ventilated pressurized gas. A stage equipped with the static-pressure bearing apparatus is also provided. The configurations, such as the shapes of the orifice 14, vent groove 11, and the exhaust groove 12, of the static-pressure bearing apparatus 1, are designed such that a laminar flow may be maintained in the entire region of the routes for ventilation of the pressurized gas. The vent groove 11 comprises the circular groove 11b and a plurality of distributing grooves 11a. The vent groove 11 is formed to be symmetrical about the centerline of the direction that the moving body 10 moves. The circular groove 11b is formed as a circle to surround the orifice 14. The plurality of distributing grooves 11a extend radially from the orifice 14 to the circular groove 11b such that the plurality of distributing grooves 11a connect the circular groove 11b and the orifice 14.
US08608380B2 Air discharge valve for a vacuum-sealed clothes bag
An air discharge valve for a vacuum-sealed clothes bag having a flexible container includes a valve body for openably closing the vacuum-sealed clothes bag. A hanger is attached to the valve body to extend upwards from the valve body, the hanger being arranged in a substantially coplanar relationship with the valve body. An anchor member is securely attached to the flexible container. First and second fixing caps are fixed to opposite surfaces of the anchor member. A cloth holder is suspended from the anchor member to hold a cloth contained in the flexible container. The valve body is fitted to the first and second fixing caps in a rotatable manner.
US08608378B2 Temperature measuring apparatus
Disclosed is a temperature measuring apparatus which is provided with: a substrate (2); a temperature sensor (3) disposed on one surface of the substrate (2); and a wire (8) disposed to electrically connect together a circuit, which detects a temperature using the temperature sensor (3), and the temperature sensor (3). In said surface of the substrate (2), a recessed section (7) having a heat capacity smaller than that of the material of the substrate (2) is formed on the periphery of the temperature sensor (3). The recessed section (7) is formed at a predetermined interval from the temperature sensor (3) such that the recessed section surrounds the temperature sensor (3) and has predetermined width and depth. Preferably, the low heat capacity zone is the recessed section (7), i.e., the groove having a recessed cross-section.
US08608377B2 Thermocouple extension wire
A thermocouple system is disclosed. The thermocouple system includes a thermocouple having a positive lead and a negative lead. A positive wire is connected at a first end to the positive lead at a first junction and at a second end to a second junction. A negative wire is connected at a first end to the negative lead at a third junction and at second end to a fourth junction. The second and fourth junctions constitute a reference junction. At least one of a thermal conductivity and a gauge of at least one of the positive wire and the negative wire are selected to govern the respective flows of heat from the first junction toward the reference junction and the flow of heat from the third junction toward the reference junction to be of such quantities that the difference in the heat flows is less than a predetermined amount.
US08608376B2 Method for modeling and parameter extraction of LDMOS devices
A method for modeling the performance of a laterally diffused metal oxide semiconductor (LDMOS) device across a wide temperature range is disclosed. The method comprises the steps of positioning the device in an environment chamber operable to create a plurality of environment temperatures; connecting the pins of the device to a measurement system operable to measure at least one device characteristic; operating the environment chamber to set a series of four environment temperatures, acquiring a value of the device characteristic from the measurement system at each temperature, and extracting a temperature parameter set based on the value of the device characteristic at each temperature, then generating a temperature-scaling model for the device.
US08608373B2 Softening point measuring apparatus and thermal conductivity measuring apparatus
In a local softening point measuring apparatus and thermal conductivity measuring apparatus using a probe microscope as a base, environment of the prob˜ and a sample surface is set to 1/100 atmospheric pressure (103 Pa) or lower. Otherwise, a side surface of the probe is coated with a thermal insulation material having a thickness that enables thermal dissipation to be reduced to 1/100 or lower, to thereby reduce the thermal dissipation from the side surface of the probe, and exchange heat substantially only at the contacting portion between the probe and the sample surface.
US08608369B2 Methods and systems for heating and mixing fluids
A fluid heating system includes a tank assembly having an interior surface bounding a chamber, the tank assembly including a sidewall and a lid. A collapsible bag is removably disposed within the chamber of the tank assembly, the collapsible bag bounding a compartment adapted to hold a fluid. A boiler can be used for pumping heated fluid through the wall of the tank assembly for heating the fluid within the collapsible bag. An impeller is disposed within the compartment of the collapsible bag. An elongated drive shaft is removably coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller within the compartment of the collapsible bag. A drive motor assembly is coupled with the drive shaft, the drive motor assembly being adapted to rotate the drive shaft when the lid is in an open or closed position.
US08608364B1 Backlight module for 3D displaying and LED light bar thereof
The present invention relates to a backlight module for 3D displaying and an LED light bar thereof. The backlight module for 3D displaying includes a light guide plate and at least one LED light bar. The LED light bar is arranged at one edge of the light guide plate. The LED light bar includes a plurality of LEDs and a substrate. The LEDs are arranged in a line and are mounted to the substrate in a mutually spaced manner. The LEDs and the substrate of the LED light bar are arranged in a plurality of sections to correspond to a predetermined backlight scanning arrangement. LED spacing set in each of the sections is less than LED spacing set between the section and an adjacent section. The present invention also provides an LED light bar of backlight module for 3D displaying.
US08608359B2 Mobile terminal having a light source and a light reflector within the mobile terminal to illuminate the mobile terminal
A mobile terminal includes a first base having a first light transmission part, the first light transmission part is configured to transmit light from an inside to an outside of the first base. A light source is arranged inside the first base and in a location capable of emitting the light to the outside of the first base via the first light transmission part. A light reflector is arranged outside the first base and in a location corresponding to the first light transmission part, and the first light reflector has a greater strength than that of the first base.
US08608358B2 Lighting device of a motor vehicle
A light module for a vehicle lighting device comprises a semiconductor light source mounted on a carrier element designed. on/including a first printed-circuit board. A control module is electrically connected to and structurally spaced from the light source and designed on/includes a second printed-circuit board and includes an electric circuit constructed upon the second board and a connection element adapted w be connected to a higher-level controller and/or vehicle power supply. The control module is an electronic component of the light source such that a cable does not connect the control module and light source to each other. A highly thermally conductive carrier module is arranged between the light source and control module and directly attached to the carrier element, second printed-circuit board, and electric circuit. An electrical connection is located on the carrier module between the fight source or carrier element and electric circuit or second printed-circuit board.
US08608353B2 Lighting appliance
A lighting apparatus having a base support member defining an inner cavity portion and configured to have an outer multi-dimensional quadric surface. A mounting member is magnetically coupled to the base support member, the mounting member being configured and operative to be movable about an outer surface of the base support member. A lighting appliance is configured to mount a lighting element wherein the lighting appliance is magnetically coupled to the mounting member, the lighting appliance is further configured and operative to be movably positionable about the magnetic mount member.
US08608349B2 Power surface mount light emitting die package
A light emitting die package includes a substrate, a reflector plate, and a lens. The substrate has traces for connecting an external electrical power source to a light emitting diode (LED) at a mounting pad. The reflector plate is coupled to the substrate and substantially surrounds the mounting pad, and includes a reflective surface to direct light from the LED in a desired direction. The lens is free to move relative to the reflector plate and is capable of being raised or lowered by the encapsulant that wets and adheres to it and is placed at an optimal distance from the LED chip(s). Heat generated by the LED during operation is drawn away from the LED by both the substrate (acting as a bottom heat sink) and the reflector plate (acting as a top heat sink).
US08608343B2 Lighting systems and methods for installing same
Embodiments of collapsible and adjustable support frames hold sockets of light strings at an equal distance and orientation to each other. Each frame can include, for example, a scissor frame with a locking slide arm on both ends to facilitate connection of the scissor frame of other scissor frames. Removable hooks that can be used from a vertical to a horizontal orientation from a gutter or any means that supports said hooks and adjustable light socket clips that can be rotated so as to be used in any orientation. This device can be adjusted and equipped with lights on the ground, thereby facilitating a reduction in the time need to install the light string. After use, the frames can be collapsed with the light string installed thereon to facilitate storage.
US08608342B2 Wire-piercing light-emitting diode light strings
A wire-piercing light-emitting diode (LED) a lead frame having a first lead and a second lead. The first lead has a first transition portion and a first bottom portion with a first cutting member, and the second lead having a second transition portion and a second bottom portion with a second cutting member.
US08608337B2 Lighting fixture having a louvered light shield
A lighting fixture having a louvered light shield is provided. The louvered light shield has at least one light emitting section with a plurality of alternating ridges and troughs. A plurality of sidewalls connect the ridges and troughs. A plurality of the ridges have a light exit opening therethrough. The light exit opening enables light from a light source of the lighting fixture to exit the lighting fixture.
US08608331B2 Backlight module
A backlight module includes a first optical film with high light reflection characteristics, a second optical film with polarization light selection transmission characteristics and light reflection characteristics, a plurality of lampshades, and a plurality of line light sources. Each lampshade has high light reflection characteristics and is disposed between optical films so that any two spaced-apart adjacent lampshades define a light mixing chamber between optical films. Each line light source is disposed in a corresponding light mixing chamber and is mounted to a corresponding lampshade for emitting light.
US08608330B2 Refrigerator and refrigerator door
Provided are a refrigerator and a refrigerator door. The refrigerator and refrigerator door include a transparent member provided behind an exterior member defining the exterior of the refrigerator, a light emitting member provided on an extending line of an outer end of the transparent member to radiate light toward the transparent member, and a diffusing portion formed at one side of the transparent member. Light from the light emitting member passes through the transparent member and a pattern on the exterior member to be diffused to the outside. Through this configuration producing a soft glow of light, aesthetics can be improved and opulence can be enhanced.
US08608329B2 Phosphor plate and illumination system with the same
A phosphor plate includes a glass layer, a wide-angle reflection dichroic filter and a phosphor layer. The wide-angle reflection dichroic filter is disposed on an exit surface of the glass layer. A first blue light and a second blue light of the incident ray are transmissible through the wide-angle reflection dichroic filter. The phosphor layer is disposed beside the wide-angle reflection dichroic filter. By the phosphor layer, the first blue light is excited as a first green light to be outputted and the second blue light is reflected to the wide-angle reflection dichroic filter. The second blue light and a portion of the first green light outputted from the phosphor layer are reflected by the wide-angle reflection dichroic filter, so that the portion of the first green light is transmitted through the phosphor layer and the second blue light is excited as a second green light by the phosphor layer.
US08608327B2 Automatic compass system for vehicle
An automatic compass system for a vehicle includes compass circuitry having a multi-axis compass sensor and associated circuitry. The multi-axis compass sensor includes first and second magnetoresponsive sensing elements. The magnetoresponsive sensing elements and at least a portion of the associated circuitry are established on a common silicon substrate using CMOS technology. The associated circuitry includes at least one of (i) an A/D converter, (ii) a D/A converter, (iii) signal processing circuitry, (iv) memory, (v) signal filtering circuitry, (vi) a display driver. The compass circuitry (i) determines a directional heading of the equipped vehicle responsive to a sensing of a magnetic field by the magnetoresponsive sensing elements and (ii) automatically compensates for a deviating magnetic field. Responsive to the compass circuitry, an information display of the equipped vehicle may display the directional heading of the equipped vehicle.
US08608326B2 Exterior mirror element with auxiliary reflector portion
A mirror reflector sub-assembly for an exterior rearview mirror assembly of a vehicle includes a mirror reflective element having a principal reflector portion and an auxiliary reflector portion. The principal reflector portion has a first radius of curvature and the auxiliary reflector portion has a second radius of curvature that is smaller than the first radius of curvature. The mirror reflective element is supported at a side of a mirror back plate and an opposing side of the mirror back plate is adapted for attaching the mirror back plate to a mirror actuator. A heater pad is disposed at a second surface of the glass substrate between the mirror reflective element and the mirror back plate. The mirror reflective element is a fixed reflectance non-electro-optic mirror reflective element and a principal mirror reflector is established at the second surface of the glass substrate at the principal reflector portion.
US08608324B1 Portable anti-condensation mirror
A portable anti-condensation mirror apparatus for use while shaving in a shower environment includes a housing having a plurality of walls that together define an interior area. A front wall of the housing defines a slot. The apparatus includes a reflection panel having a first end operatively coupled to the housing and an opposed free end, the reflection panel being movable between a retracted configuration substantially inside the interior area and an extended configuration extending through the slot and substantially outside the interior area. At least one housing suction cup is mounted to a rear wall of the housing so as to selectively mount the housing in a shower. A heating member is positioned in the interior area and configured to generate heat inside the interior area when energized by a battery.
US08608323B2 Barrier layer and a method of manufacturing the barrier layer
A barrier layer capable of preventing permeability of moisture, oxygen, other gases, solvents and volatile organic compounds is provided. The barrier layer includes a surface profile undulating in all directions. Further, the surface profile is characterized by the absence of non-undulating surface, straight lines and sharp edges. Further, the surface profile bends in reaction to at least one of thermal stress, mechanical stress, and load caused by deformation of an adjoining substrate or layer. This allows the barrier layer to stretch and shrink in all directions in a plane along the surface profile of the barrier layer and prevents cracking of the barrier layer.
US08608318B2 Wireless projector apparatus and wireless LAN adapter
A wireless LAN adaptor includes an auto-run program for a connection process, containing a projector identifier for specifying a connection destination. In the process while this auto-run program is executed, an electric field intensity measuring unit measures the electric field intensity of a response radio wave from the wireless projector. The control unit interrupts connection operation and makes the display unit of the PC produce a display for requesting judgment when the electric field intensity is smaller than a predetermined value.
US08608317B2 Projection of various image contents in a cabin of a transport means
According to an embodiment of the present invention a projection facility for projecting image contents onto an inside wall in an open cabin of a transport means, with which any given image contents can be projected onto a curved inside wall in a large-scale manner. The projection facility may comprise, apart from several projectors, several mirrors for deflecting the image contents. This allows image quality to be improved.
US08608316B2 Cooling and air flow exhaust for image projection apparatus
An image projection apparatus is disclosed which is capable of reducing noise when airflows from plural flow paths are taken in into a fan and exhausted therefrom. The apparatus comprises a first flow path through which a first airflow for cooling a light source passes, a second flow path through which a second airflow for cooling constituent parts other than the light source passes, a fan which exhausts air introduced from the first and second flow paths to the outside of the apparatus, a third flow path which introduces a third airflow to an exhaust area between the light source and the fan in the first flow path, and a light-shielding member which is provided in the exhaust area and shields the light from the light source.
US08608309B2 Eyeglass system
An eyeglass system having interchangeable components. The eyeglass system includes right and left temples that are connected to a front frame via a decorative pin. The pin is easily removed to allow one to replace the temples with those having another style, or use the temples with another frame. A front cover can also be connected to the frame via the pin to further change the style or design of the eyeglasses.
US08608308B2 Image recording device
An image recording device comprises a housing, a sheet cassette, a recording unit, and a convey path defining member. The housing has an opening. The sheet cassette is configured to hold therein sheets and configured to be inserted into and removed from the housing through the opening. The recording unit is configured to record an image on a sheet conveyed from the sheet cassette along a convey path. The convey path defining member is configured to pivot, about a pivot shaft supported by the housing, between a guiding position for forming a guide surface that defines a part of the convey path, and an exposing position for exposing the part of the convey path to the opening. The convey path defining member is configured to pivot in response to insertion and removal of the sheet cassette.
US08608307B2 Transfix roller for use in an indirect printer with an image receiving member having a thin wall
A transfix roller is adapted for use with a thin walled image receiving member in an indirect printer. The transfix roller is centrally supported to present a more uniform pressure profile in the nip formed with the image receiving member. An interference fit between the central shaft and the roller sleeve enables the transfix roller to be made without an additional process to secure the shaft to the sleeve.
US08608300B2 Liquid circulation system and ink-jet printer
An ink circulation system includes: an ink-jet head in which a shared ink flowing route is formed, an ink tank, a supply flowing route for supplying ink from the ink tank to the shared ink flowing route, a reflux flowing route for refluxing the ink from the shared ink flowing route to the ink tank, and a differential pressure generating unit for generating a differential pressure in the ink tank. The differential pressure generating unit is equipped with an impeller placed inside the ink tank, and a drive unit placed outside the ink tank. Then, the drive unit operates to turn the impeller, by means of remote driving, for generating a differential pressure between a supply port of the supply flowing route and a reflux port of the reflux flowing route so as to circulate the ink through the ink flowing route.
US08608295B2 Piezoelectric element, liquid ejecting head, and liquid ejecting apparatus
A piezoelectric element comprises a piezoelectric layer consisting a complex oxide having a perovskite structure containing bismuth and iron and electrodes provided to the piezoelectric layer. The complex oxide further contains a first dopant element that is magnesium and a second dopant element that is at least one of manganese, titanium, vanadium, niobium and tin.