最新美国发明专利第2013-12-03期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08598515B2	Mass spectrometry systems Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.
US08598513B2	Mass spectrometer A mass spectrometer is disclosed wherein a signal output from an ion detector is digitised using an Analogue to Digital Converter. A background or baseline level is dynamically subtracted from the digitised signal whilst the time of flight data is still being acquired. A threshold is also applied dynamically to the digitised signal in order to reduce electronic noise.
US08598511B1	Carbon nanotube anchor for mass spectrometer This invention enables a sensitivity enhancement in the detection of molecular compounds. A mass spectrometry analyte support with nanotube anchors are used to concentrate MALDI samples, specifically samples prepared with water-insoluble matrix compounds, on the anchor spot. The surface structure is established through patterned carbon nanotube anchor growth, providing a nucleation center for analyte and reducing sample precipitation on the surrounding MALDI wafer. Also disclosed is a method of creating a mass spectrometry support using patterned metal catalyst to grow carbon nanotubes. The carbon nanotubes enhance nucleation on specific areas of a sample plate to concentrate analyte/matrix deposit during droplet evaporation.
US08598502B2	Motionless focus evaluation test station for electro-optic (EO) sensors A motionless focus evaluation test station is provided for measuring detector position error of EO sensors that do not possess dynamic focus capability. A positionally-fixed source emits EM radiation that diverges along an optical axis of the test station. Collimating optics collimate the EM radiation and direct it along the optical axis to the EO sensor. A positionally-fixed target is placed in the path of the diverging EM radiation nominally at the focal plane of the collimating optics. The target comprises a limiting aperture that exhibits an induced shift in optical focus at different positions along the aperture such that different positions on the target are imaged to different focal planes at the detector. The detector captures an image of the target that is blurred to either side of the spatial position that is optically conjugate to the actual detector position. A processor processes the image to measure the blur as function of spatial position to measure the actual detector position and output detector position error from a desired detector position.
US08598499B2	Roll-out thermal envelope roof de-icing system A flexible roll-out thermal system, including: a layer of insulating material forming a first outer surface; a layer of conductive material forming a second outer surface; at least one electric heating cable disposed between the first and second outer surfaces; and, an electrical connection element for connecting the at least one electric heating cable to a power source. A method of forming a flexible roll-out thermal system, including: disposing at least one electric heating cable between a layer of insulating material forming a first outer surface and a layer of conductive material forming a second outer surface; and connecting an electrical connection element to one end of the at least one electric heating cable, the electrical connection element for connecting the at least one electric heating cable to a power source.
US08598491B2	GTAW welder An improvement in a welder including a power source for performing a TIG welding process across an electrode and a workpiece where the power source has a first output lead connected to the electrode and a second output lead connected to the workpiece with a controller for creating a waveform across the power leads. The waveform has a profile alternating between a first current section and a second current section at a given overall frequency and the sections each have a peak current in either the positive or negative direction and a duration. The improvement comprises at least one of the current sections being pulsed between a high current level equal to its peak current and a low current level in the opposite direction of the peak current at a pulsing frequency greater than the given overall frequency.
US08598488B2	Method and apparatus for adjusting radiation spot size An apparatus can include a first beam cropper configured to crop a portion of a radiation pulse having a first spot size to form an intermediate cropped radiation pulse having an intermediate cropped spot with an intermediate cropped spot size less than the first spot size; and a second beam cropper configured to crop the intermediate cropped spot to form a second cropped radiation pulse having a second cropped spot with a second cropped spot size less the intermediate cropped spot size.
US08598479B2	Electronic device with push button An electronic device includes a switch, a housing, a button, and an elastic element. The housing includes a cover and a sidewall enclosing the cover. The sidewall defines a receiving hole. The button is received in the receiving hole. The elastic element includes a base, a resisting portion, and an angled elastic arm connecting the resisting portion to the base. The resisting portion abuts against the button. The base is fixed to the cover. The elastic arm deflects when the button is pushed by an external force to actuate the switch, and rebounds to cause the button to move back when the external force has ceased.
US08598471B2	Electric storage device There is provided an electric storage device having a novel fastening structure of a plastic member which can reduce cost with a simple configuration. An electric storage device according to this invention includes an electrode assembly, a case housing the electrode assembly, a plastic member arranged at an outer surface of the case, the plastic member having a joining surface facing the outer surface of the case, and an external terminal supported by the plastic member and electrically connected to the electrode assembly. The plastic member is a synthetic resin containing an inorganic fiber and is bonded to the outer surface of the case with the inorganic fiber exposed at the joining surface.
US08598468B2	Electromagnetic bandgap structure and printed circuit board An electromagnetic bandgap structure including: at least three conductive plates; a first stitching via, configured to electrically connect any one of the conductive plates to another conductive plate; and a second stitching via, configured to electrically connect the one conductive plate to yet another conductive plate, wherein the first stitching via electrically connects the one conductive plate to another conductive plate by allowing a part of the first stitching via to be connected through a planar surface above or below the one conductive plate, and the second stitching via electrically connects the one conductive plate to yet another conductive plate by allowing a part of the second stitching via to be connected through a planar surface that is different from the planar surface through which the part of the first stitching via is connected, the two planar surfaces being placed in a same direction based on the conductive plates.
US08598465B2	Hermetic circuit ring for BCB WSA circuits A wafer-scale assembly circuit including a plurality of metal interconnect layers, where each metal layer includes patterned metal portions and where at least some of the patterned metal portions are RF signal lines. The circuit further includes at least one benzocyclobutene layer provided between two metal interconnect layers that includes at least one trench via formed around a perimeter of the benzocyclobutene layer at a circuit sealing ring, where the trench via provides a hermetic seal at the sealing ring. The benzocyclobutene layer also includes a plurality of stabilizing post vias formed through the benzocyclobutene layer adjacent to the trench via proximate to the sealing ring and extending around the perimeter of the benzocyclobutene layer, where the stabilizing vias operate to prevent the benzocyclobutene layer from shrinking in size.
US08598464B2	Soldering material and electronic component assembly A solder material includes 1.0-4.0% by weight of Ag, 4.0-6.0% by weight of In, 0.1-1.0% by weight of Bi, 1% by weight or less (excluding 0% by weight) of a sum of one or more elements selected from the group consisting of Cu, Ni, Co, Fe and Sb, and a remainder of Sn. When a copper-containing electrode part of an electronic component is connected to a copper-containing electrode land of a substrate by using this solder material, a part having an excellent stress relaxation property can be formed in the solder-connecting part and a Cu—Sn intermetallic compound can be rapidly grown from the electrode land and the electrode part to form a strong blocking structure.
US08598463B2	Circuit board and manufacturing method thereof A circuit board includes a metal pattern layer, a thermally conductive plate, an electrically insulating layer, and at least one electrically insulating material. The thermally conductive plate has a plane. The electrically insulating layer is disposed between the metal pattern layer and the plane and partially covers the plane. The electrically insulating material covers the plane where is not covered by the electrically insulating layer and touches the thermally conductive plate. The electrically insulating layer exposes the electrically insulating material, and a thermal conductivity of the electrically insulating material is larger than a thermal conductivity of the electrically insulating layer.
US08598462B2	Cable management apparatus A cable management apparatus includes a securing board and a cable management element. The securing board defines a first slot and a second slot. An extending direction of the first slot is substantially perpendicular to an extending direction of the second slot. The cable management includes a base panel, a connecting portion, a positioning tab corresponding to the first slot, a resilient tab corresponding to the second slot, and a securing panel extending from the base panel. The securing panel includes a panel body and a securing portion. The connecting portion includes a first connecting panel and a second connecting panel. A receiving space is defined between the panel body and the first connecting panel. The second connecting panel has a free end. The second connecting panel is capable of moving relative to the first connecting panel to enable the free end to be engaged in the securing portion.
US08598457B2	Flexible electrical line A flexible electrical line has at least one sensor element with two leads in a core, the leads made from insulated electrical conductors which are surrounded by a common outer casing of insulation material. The core is three phase leads of a conductor and insulation which are stranded together for energy transmission. The conductors of the leads are copper wires which surround a tension-proof central element in two layers with oppositely directed threading direction. The insulation of the leads is a cross-linked elastomer material applied by extrusion with a dielectricity number of at least 6.0 at room temperature. The unit, composed of leads and filler strands of the sensor element, is surrounded by a casing of an electrically conductive polymer material, and the core of the line is surrounded by a common inner casing produced by extrusion over which is arranged the outer casing.
US08598434B1	Maize variety hybrid X03B453 A novel maize variety designated X03B453 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03B453 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03B453 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03B453, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03B453. This invention further relates to methods for producing maize varieties derived from maize variety X03B453.
US08598431B1	Maize variety hybrid X03B491 A novel maize variety designated X03B491 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03B491 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03B491 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03B491, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03B491. This invention further relates to methods for producing maize varieties derived from maize variety X03B491.
US08598428B1	Maize variety hybrid X00B150 A novel maize variety designated X00B150 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00B150 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00B150 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00B150, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00B150. This invention further relates to methods for producing maize varieties derived from maize variety X00B150.
US08598425B2	Celery cultivar ADS-23 A celery cultivar, designated ADS-23, is disclosed. The invention relates to the seeds of celery cultivar ADS-23, to the plants of celery cultivar ADS-23 and to methods for producing a celery plant by crossing the cultivar ADS-23 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-23, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-23 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-23 with another celery cultivar.
US08598416B1	Soybean cultivar OW0913010 The present invention is in the field of soybean variety OW0913010 breeding and development. The present invention particularly relates to the soybean variety OW0913010 and its progeny, and methods of making OW0913010.
US08598412B2	Seed specific USP promoters for expressing genes in plants The present invention relates to the field of plant genetic engineering. More specifically, the present invention relates to seed specific gene expression. The present invention provides promoters capable of transcribing heterologous nucleic acid sequences in seeds, and methods of modifying, producing, and using the same.
US08598410B2	Method and compositions for the production of transgenic plants The present invention relates generally to a process of producing transgenic plants and more particularly transgenic oil palm plants carrying exogenous genetic material which confers on said plants or cells of said plants particular phenotypic traits. The present invention further provides plant parts, reproductive material and plant products from the transgenic plants. The present invention particularly provides transgenic plants and even more particularly transgenic oil plants having beneficial and useful phenotypic characteristics not present at least to the same extent in non-transgenic plants of the same species. The present invention is further directed to oil, and particularly palm oil, having beneficial and desirable characteristics, produced by the transgenic plants made in accordance with the present invention.
US08598399B2	Catalyst composition for direct conversion of ethanol to propylene A process to prepare propylene showing desirably increased selectivity comprises contacting, at an elevated temperature, ethanol and a rhenium oxide-modified ZSM-5 zeolite catalyst, under conditions suitable to form propylene. The rhenium oxide-modified ZSM-5 zeolite catalyst may be prepared by impregnating, in an aqueous or organic medium, a ZSM-5 zeolite with a rhenium source, under conditions suitable to form a catalyst precursor, and calcining the catalyst precursor under conditions suitable to form a rhenium oxide-modified ZSM-5 zeolite catalyst.
US08598397B2	Method for the treatment of a small-and/or medium-pore zeolite and use thereof in the oligomerisation of light olefins Described is a process for the treatment of at least one zeolite having a pore size of less than or equal to 7 Å comprising at least a) a step for dealumination of said zeolite, b) a cationic exchange step using at least one cation other than H+, c) a step for treatment of said zeolite obtained in step b) in the presence of at least one molecular compound containing at least one silicon atom, and d) at least one heat treatment step. The present invention also concerns the preparation of a catalyst containing the zeolite treated in accordance with the treatment process the subject-matter of the invention and the use of said catalyst in a process for the oligomerization of an olefinic charge containing hydrocarbon molecules having from 2 to 12 carbon atoms per molecule.
US08598392B2	Continuous method for producing substituted cyclohexylmethanols The present invention relates to a continuous process for preparing para-alkyl-substituted cyclohexylmethanols, especially 4-isopropylcyclohexylmethanol, by catalytically hydrogenating the corresponding aldehydes or ketones in the presence of hydrogen and in the presence of a catalyst which comprises, as an active metal, ruthenium applied to a support, the support comprising Al2O3 and/or SiO2, and the catalyst being used in the form of a fixed bed catalyst in a hydrogenation reactor or in a plurality of hydrogenation reactors connected in series.
US08598390B2	Controlling the normal:ISO aldehyde ratio in a mixed ligand hydroformylation process A method of controlling an in-series, multiple, e.g., two, reaction zone, hydroformylation process for producing normal (N) and iso (I) aldehydes at a N:I ratio, the process comprising contacting an olefinically unsaturated compound with synthesis gas and a catalyst comprising (A) a transition metal, e.g., rhodium, (B) an organobisphosphite ligand, and (C) an organomonophosphite ligand, the contacting conducted in first and subsequent reaction zone(s) and at hydroformylation conditions comprising a transition metal concentration in each zone, the method comprising decreasing the transition metal concentration in the first reaction zone to decrease the N:I ratio or increasing the transition metal concentration in the first reaction zone to increase the N:I ratio.
US08598387B2	Process for the preparation of atovaquone Disclosed herein is novel process for preparation of atovaquone, which process includes reacting 1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.
US08598386B2	Process for producing lacosamide The present invention relates to a method for producing (R)-2-acetamido-N-benzyl-3-methoxypropionamide (lacosamide), by methylation of (R)-2-acetamino-2-N-benzyl-3-hydroxy-propionamide (V), in which the methylation is carried out at a temperature below 20° C.
US08598385B2	Process for the preparation of N-vinylcarboxamides Process for the preparation of N-vinylcarboxamides by pyrolysis of a compound of the formula CH3—CH(CN)—N(R)—CO—R1 (I), in which R and R1 are H or C1- to C6-alkyl, in the presence of solids which are doped with alkali metal or alkaline earth metal ions, under reduced pressure at a temperature of from 330 to 750° C. with elimination of hydrogen cyanide, cooling, separation and isolation of the reaction products, a solid arranged in a tubular reactor being treated at a temperature in the range from 0 to 250° C. with a solution of an alkali metal and/or alkaline earth metal base, the solution being discharged, the remaining solvent which adheres to the catalyst thus obtainable being evaporated and said catalyst then being heated to a temperature of at least 380° C. for activation.
US08598383B2	Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases The present invention relates to a pharmaceutical composition useful for treating or preventing inflammatory disease and cell damage, and a method for treating or preventing inflammatory disease and cell damage. The present invention uses the 2-hydroxybenzoic acid derivative represented by the specific chemical formula or its pharmaceutically acceptable salt. The compound of the present invention is useful for treating or preventing cell damage and inflammatory disease including gastritis, gastric ulcer, pancreatitis, colitis, arthritis, diabetes, arteriosclerosis, nephritis, hepatitis, Alzheimer's disease, Parkinson's disease and Lou Gehrig's disease.
US08598378B2	Methods and compositions for extraction and transesterification of biomass components Methods and compositions are disclosed for the direct transesterification and extraction of bio-lipids and bio-oils in the production of biofuel, particularly fatty acid methyl ester products.
US08598375B2	Method of preparing dichloropropanol using glycerol with improved selectivity for dichloropropanol A method of preparing dichloropropanol using glycerol. The method includes: chlorination of glycerol including a plurality of chlorination reaction stages using a catalyst; and a water-removing stage performed between the reaction stages, independently of the reaction stages.
US08598371B2	Bidentate chiral ligands for use in catalytic asymmetric addition reactions Compounds of the formula (I) in the form of a mixture of predominantly one diastereomer or in the form of pure diastereomers, Z1-Q-PR0R1 (I), wherein: Z1 is a C-bonded, secondary phosphine group of the formula —P(R)2, wherein R is a hydrocarbon radical or O-atom(s)-containing heterohydrocarbon radical having 1 to 18 carbon atoms and optionally substituted by C1-C6-alkyl, trifluoromethyl, C1-C6-alkoxy, trifluoromethoxy, (C1-C4-alkyl)2amino, (C6H5)3Si, (C1-C12-alkyl)3Si or halogen; Q is selected from the group consisting of: (i) an optionally substituted achiral aromatic group, wherein the achiral aromatic group is bonded directly to Z1 through a carbon atom of the achiral aromatic group and bonded directly to PR0R1 through a carbon atom of the achiral aromatic group, and (ii) an optionally substituted C1-C4-alkylene group; P* is a chiral phosphorus atom; R0 is methyl; and R1 is a C-bonded optically enriched or optically pure chiral, mono- or polycyclic, nonaromatic hydrocarbon ring; and preparation and use.
US08598368B2	Stable neutral nitric oxide source C-nitroso compound capable of releasing neutral nitric oxide is made stable by forming a Diels Alder adduct thereof which is functionalized at the Diels-Alder double bond to impart the stability. Treatment of the stabilized adduct with agent that removes functionalization and regenerates Diels Alder double bond triggers delivery of neutral nitric oxide via retro Diels-Alder reaction and homolytic scission.
US08598366B2	Compounds for the treatment of proliferative disorders The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
US08598363B2	Process for manufacturing 2-[(3,5-difluoro-3′-methoxy-1,1′biphenyl-4-yl)amino]nicotinic acid The present disclosure relates to a process for manufacturing 2-[(3,5-difluoro-3′-methoxy-1,1′biphenyl-4-yl)amino]nicotinic acid.
US08598362B2	Methods for the preparation of charged crosslinkers Processes for the preparation of charged crosslinkers bearing a sulfonic acid moiety are disclosed. These procedures also optionally include methods to convert the resulting products to substantially a single salt form.
US08598355B2	Amide compound [Problems] A compound, which is useful as an active ingredient of a pharmaceutical composition, for example, a pharmaceutical composition for treating chronic renal failure and/or diabetic nephropathy, is provided.[Solving Means] The present inventors have conducted extensive studies on a compound having an EP4 receptor antagonistic activity, and confirmed that the amide compound of the present invention has an EP4 receptor antagonistic activity, thereby completing the present invention. The amide compound of the present invention has an EP4 receptor antagonistic activity, and can be used as an active ingredient of a pharmaceutical composition for preventing and/or treating various EP4-related diseases, for example, chronic renal failure and/or diabetic nephropathy, and the like.
US08598354B2	Compounds having antiparasitic or anti-infectious activity Compounds of formula I: or formula II: or a pharmaceutically acceptable salt of formula I or formula II, wherein: R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl; R2 is methyl or haloalkyl; R4 is hydroxyl, carbonyloxy, or carbonyldioxy; and R3 is aliphatic, aryl, aralkyl, or alkylaryl; and R5, R6, R7 and R8 are each individually H, halogen, alkoxy, alkyl, haloalkyl, aryl, nitro, cyano, amino, amido, acyl, carboxyl, substituted carboxyl, or —SO2R10, wherein R10 is H, alkyl, amino or haloalkyl; provided that in formula I, R5 and R7 are not both H or R6 is not H or methoxy; and in formula II that if R4 is carbonyldioxy then R7 is not methoxy.
US08598347B2	Method for manufacturing dipeptidyl peptidase-IV inhibitor and intermediate The present invention relates to an improved method for manufacturing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention allows reduction of production costs by reacting low cost reagents, improves yield and is adaptable for mass production.
US08598346B2	Synthesis of cyclic amidines The invention relates to an innovative method for synthesis of cyclic amidines. The synthesis starts from a β-, γ- or δ-lactone which is twofold brominated. After esterification of the carboxyl function, the bromine atoms are nucleophilically substituted and the corresponding diamino compound is obtained. The ring closure to the cyclic amidine is accomplished subsequently by reaction with orthoester, imidate or thioimidate. Owing to interposing additional steps for recovery of the diamino compound in enantiomerically pure form, the enantiomers of the cyclic amidines can be stereoselectively synthesized.
US08598345B2	Substituted heteroarylamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08598344B2	CDKI pathway inhibitors and uses thereof The invention relates to compounds for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases.
US08598341B2	Process for etravirine intermediate and polymorphs of etravirine 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile is a key intermediate for the preparation of etravirine. The present invention provides a process for preparation of 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile. The present invention also provides a novel process for the preparation of etravirine crystalline form I. The present invention further provides novel crystalline forms of etravirine, processes for their preparation and pharmaceutical compositions comprising them.
US08598340B2	Spirooxazine radical derivatives and reversible isomerization reaction The present invention can provide new spirooxazine radical derivatives of the following general formula (1) which have chromic property enabling the distinction between the radical species and the cation species on the basis of absorption wavelength:
US08598335B2	Organic compositions to treat Beta-ENaC-related diseases The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.
US08598326B2	Polynucleotide encoding a fusion polypeptide suitable as cytotoxin The present invention relates to fusion polypeptides including (a) a binding site for a cytoskeleton component and (b1) an effector protein or the catalytic domain thereof or (b2) a binding site for the effector protein, and nucleic acid sequences encoding the fusion polypeptides. Moreover, various therapeutic uses of the fusion polypeptides are described, e.g., the treatment of diseases associated with the presence of an aberrant cell population, preferably cancer or AIDS.
US08598325B2	Solid-phase microextraction coatings and methods for their preparation There is described a coated solid phase microextraction (SPME) fiber for use in direct immersion SPME of a food matrix that includes carbohydrates. The coated SPME fiber includes a SPME fiber for absorbing a small molecule from the food matrix; and a protective coating which has a surface that is substantially uniform and substantially smooth, the protective coating reducing adsorption of the carbohydrates onto the SPME fiber and allowing the SPME fiber to extract the small molecule from the food matrix. A process for producing the coated SPME fiber and a method of performing solid phase microextraction are also described.
US08598324B2	Anti-pathogen treatments Chimeric molecules that contain at least one pathogen-detection domain and at least one effector domain, and their methods of use in preventing or treating a pathogen infection in a cell or organism are described. The pathogen-detection domain and effector domain of the chimeric molecules are domains not typically found in nature to be associated together. Agents are also described herein having at least one pathogen-interacting molecular structure and at least one effector-mediating molecular structure, the agent being one that is non-naturally-occurring in a cell. The methods of prevention and treatment described herein are effective for a broad spectrum of pathogens and exhibit little or no toxic side-effects. Assays for the detection of a pathogen, pathogen component, or product produced or induced by a pathogen, are also provided.
US08598321B2	Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins This invention provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
US08598319B2	Process for separating proteins fibrinogen, factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins The invention is related to a process for separating proteins fibrinogen, Factor XIII and biological glue from a solubilized plasma fraction and for preparing freeze-dried concentrates of said proteins comprising the steps of: chromatographic purification comprising the steps of loading an anion exchanger of weak base type with the said solubilized fraction, previously equilibrated with a buffer of a predetermined ionic strength of an alkaline pH, which allows to retain the biological glue, elution of the biological glue by increasing the ionic strength of the said buffer, and separation of FXIII from fibrinogen by addition to at least one part of the biological glue eluate of at least one chemical agent precipitating the FXIII, and recovery of the resulting purified fibrinogen containing supernatant solution, and diafiltration of the fibrinogen, biological glue and resolubilized FXIII solutions, followed by a freeze-drying of said solutions.
US08598317B2	Muteins of tear lipocalin with affinity for the T-cell coreceptor CD4 The present invention relates to a mutein of human tear lipocalin, wherein the mutein comprises at least one mutated amino acid residue at any two or more of the sequence positions 24-36, 53-66, 79-84, and 102-110 (or 103-110) of the linear polypeptide sequence of the mature human tear lipocalin, and wherein the mutein binds to the extracellular region of the T-cell coreceptor CD4 with detectable affinity. The invention also relates to a method of generating such a mutein as well as to various pharmaceutical uses of such a mutein.
US08598315B2	Protein transduction domains derived from secretory leukocyte protease inhibitor This invention relates to novel protein transduction domains (PTDs) derived from secretory leukocyte protease inhibitor (SLPI). SLPI-derived PTDs are able to deliver cargo moieties in vivo and in vitro into the cytoplasm and nucleus of a host cell. The invention also relates to a transduction complex comprising one or more SLPI-derived PTDs linked or fused to one or more cargo moieties, which may comprise, for example, proteins, nucleic acids, lipids, carbohydrates, small molecules and other chemical compounds. The invention also relates to the manufacture of SLPI-derived PTDs, complexes comprising them; compositions comprising SLPI-derived PTDs or complexes; and utilization of SLPI-derived PTDs or complexes comprising them for therapeutic, diagnostic and research methods involving delivery of heterologous molecules across cellular membranes, and especially, across nuclear membranes.
US08598312B2	Inhibitors of antigen presentation by MHC class II molecules The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
US08598309B2	Catalytic system of nitrate anions for CO2/epoxide copolymerization This invention relates to a Salen type ligand including three or more quaternary ammonium salts of nitrate anions, to a trivalent metal complex compound prepared from this ligand and a method of preparing the same, to a method of preparing polycarbonate by copolymerizing an epoxide compound and carbon dioxide using the complex compound as a catalyst, and to a method of separating and collecting the catalyst from the copolymer after copolymerization. This catalyst used to copolymerize an epoxide compound and carbon dioxide can be more simply prepared, and has lower catalyst preparation and recovery costs, and higher activity, compared to conventional catalysts.
US08598308B2	Multifunctional dendrons and dendrimers with a high loading capacity The invention relates to novel multifunctional dendrimer structures with a high loading capacity. Said dendrimer structures include a nucleus having at least a first generation or an end generation covalently bonded thereto. The first generation is formed by at least two of the following structures, namely: a spacer, a load, a branching element. In addition, a plurality of sequences (known as intermediary generations) with at least two of the aforementioned structures can be joined to the first generation. The terminal generation is formed by at least three of the following structures, namely: a spacer, a load, a branching element and a terminal.
US08598307B2	Phosphorus-containing compounds and their preparation process and use A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
US08598305B2	Conjugated polymers and devices incorporating same Disclosed are conjugated polymers having desirable properties as semiconducting materials. Such polymers can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability.
US08598304B2	Poly(5,5′bis(thiophen-2-yl)-benzo[2,1-b;3,4-b′]dithiophene) and its use as high performance solution processable semiconducting polymer Poly(5,5′-bis(thiophen-2-yl)-benzo[2,1-b;3,4-b′]dithiophene) comprising as repeating units the group of the formula (I) wherein R is independently selected from a) a C1-20 alkyl group, b) a C2-20 alkenyl group, c) a C2-20 alkynyl group, d) a C1-20 alkoxy group, e) a —Y—C3-10 cycloalkyl group, f) a —Y—C6-14 aryl group, g) a —Y-3-12 membered cycloheteroalkyl group, or h) a —Y-5-14 membered heteroaryl group, wherein each of the C1-20 alkyl group, the C2-20 alkenyl group, the C2-20 alkynyl group, the C3-10 cycloalkyl group, the C6-14 aryl group, the 3-12 membered cycloheteroalkyl group, and the 5-14 membered heteroaryl group is optionally substituted with 1-4 R1 groups, R1 is independently selected from a) a S(O)m—C1-20 alkyl group, b) a S(O)m—OC1-20 alkyl group, c) a S(O)m—OC6-14 aryl group, d) a C(O)—OC1-20 alkyl group, e) a C(O)—OC6-14 aryl group, f) a C1-20 alkyl group, g) a C2-20 alkenyl group, h) a C2-20 alkynyl group, i) a C1-20 alkoxy group, j) a C3-10 cycloalkyl group, k) a C6-14 aryl group, l) a 3-12 membered cycloheteroalkyl group, or m) a 5-14 membered heteroaryl group, Y is independently selected from a divalent C1-6 alkyl group, or a covalent bond; and m is independently selected from 0, 1, or 2, and having a number average molecular weight Mn in the range of from 5,000 to 200,000 g/mol.
US08598299B2	Semiconductor composition A semiconductor composition for producing a semiconducting layer with consistently high mobility is disclosed. The semiconductor composition includes a diketopyrrolopyrrole-thiophene copolymer and a non-aromatic halogenated hydrocarbon solvent. The copolymer has a structure disclosed within. Preferably, the non-aromatic halogenated hydrocarbon solvent contains at least 2 carbon atoms and at least 3 halogen atoms.
US08598298B2	Flame retardant thermoplastic elastomer composition with resistance to scratch-whitening Halogen-free, flame-retardant thermoplastic polyester elastomer (TPE-E) compositions that include at least one thermoplastic polyester elastomer, at least one low-melting, phosphorus-based flame retardant having a melting temperature no higher than 150° C., and a blend of solid intumescent flame retardants comprising a phosphorus-based, organic salt flame retardant and a nitrogen-based organic flame retardant are provided. The presence of the low-melting, phosphorus-based flame retardant renders the compositions more resistant to scratch-whitening.
US08598296B2	Organohydrogenpolysiloxane, making method, and addition-cure silicone composition An organohydrogenpolysiloxane comprising at least two structural units of —(HR1SiO)a— wherein R1 is a monovalent hydrocarbon group, and a is an integer of 2-50, which are connected together via a SiH-free structural unit, is a novel crosslinking agent. A silicone composition comprising an alkenyl-containing organopolysiloxane, the organohydrogen-polysiloxane, and a catalyst is curable through addition reaction, adherent to plastic substrates, and useful for coating purposes.
US08598294B2	Self-adhesive hardener composition Hardener composition for condensation-crosslinking RTV-2 silicone compositions contain (A) at least one crosslinker, (B) at least one crosslinking catalyst which is an alkali metal or alkaline earth metal compound which is not a hydroxide, and (D) at least one functional silane as a coupling agent.
US08598291B2	Antifouling composition, method for its production and article treated therewith Antifouling composition containing a fluorocopolymer which contains from 30 to 70 mass % of polymerized units (a′) having a C1-6 perfluoroalkyl group, from 20 to 69 mass % of polymerized units (b′) having an alkylene oxide chain and from 1 to 10 mass % of polymerized units (c′) having an amino group, and which has anionic groups at its main chain terminals. Method of making.
US08598290B2	Method for producing fluorine-containing elastomer The present invention provides a method of producing a fluoroelastomer excellent in dispersion stability at low cost, at a high rate of polymerization and in high yields. The present invention is a method of producing a fluoroelastomer comprising an emulsion polymerization of a fluorinated monomer in the presence of a water-soluble radical polymerization initiator, wherein the emulsion polymerization is carried out in the presence of a compound (1) containing a functional group reactive in radical polymerization and a hydrophilic group and a fluorinated compound (2) containing a fluorocarbon group comprising 1 to 6 continuously united carbon atom with fluorine atom directly bound to each of them as well as a hydrophilic group.
US08598288B2	Catalyst for polymerization of norbornene monomers, method for producing norbornene polymer, method for producing norbornene copolymer, norbornene polymer and transition metal complex A catalyst for a polymerization of norbornene monomers includes a transition metal complex represented by a formula (1). A method for producing a norbornene copolymer includes copolymerizing first norbornene monomers corresponding to a first monomer unit represented by a formula (2) and second norbornene monomers corresponding to a second monomer unit represented by a formula (3) in a presence of the catalyst. The transition metal complex is preferably (π-allyl) {2-[N-(2,6-diisopropylphenyl) iminomethyl]phenolate}palladium, (π-allyl) {2-[N-(2,6-diisopropylphenyl)iminomethyl]-4-fluorophenolate}palladium, (π-allyl)[2-(N-phenyliminomethyl) phenolate]palladium or (π-allyl){2-[N-(2,6-diisopropylphenyl) iminomethyl]-6-methylphenolate}palladium.
US08598287B2	Metallocene catalysts and their use in polymerization processes A process for polymerizing olefin(s) utilizing a cyclic bridged metallocene catalyst system to produce polymers with improved properties is provided. The catalyst system may include a cyclic bridged metallocene, LA(R′SiR′)LBZrQ2, activated by an activator, the activator comprising aluminoxane, a modified aluminoxane, or a mixture thereof, and supported by a support, where: LA and LB are independently an unsubstituted or a substituted cyclopentadienyl ligand bonded to Zr and defined by the formula (C5H4-dRd), where R is hydrogen, a hydrocarbyl substituent, a substituted hydrocarbyl substituent, or a heteroatom substituent, and where d is 0, 1, 2, 3 or 4; LA and LB are connected to one another with a cyclic silicon bridge, R′SiR′, where R′ are independently hydrocarbyl or substituted hydrocarbyl substituents that are connected with each other to form a silacycle ring; and each Q is a labile hydrocarbyl or a substituted hydrocarbyl ligand.
US08598285B2	Process for the preparation of polymer of 1-butene A process for the preparation of 1-butene homopolymers or 1-butene/alpha olefin copolymers wherein the alpha olefins are selected from ethylene, propylene or alpha olefins of formula CH2═CHZ wherein Z is a C3-C20 alkyl radical, comprising contacting 1-butene or 1-butene and one or more alpha olefins under polymerization conditions in the presence of a catalyst system comprising: (a) a solid component comprising a Ti compound and an internal electron-donor compound supported on MgCl2 (b) an alkylaluminum cocatalyst; and (c) a compound of formula (I) as external donor.
US08598284B2	Oxygen-bridged bimetallic complex and polymerization process An oxygen-bridged bimetallic complex of the general formula (I) Cp2R1M1-O-M2R22Cp (I), wherein Cp is independently a cyclopentadienyl, indenyl or fluorenyl ligand which can be substituted, or a ligand isolobal to cyclopentadienyl, R1, R2 independently are halide, linear or branched or cyclic alkyl, aryl, amido, phosphido, alkoxy or aryloxy groups, which can be substituted, M1 is Zr, Ti or Hf, and M2 is Ti, Zn, Zr or a rare earth metal. The complex can be useful as a polymerization catalyst.
US08598282B2	High adhesiveness silicone resin composition and an optical semiconductor device provided with a cured product thereof The object of the present invention is to provide a silicone resin composition for encapsulating an optical semiconductor element which has strong adhesiveness to a substrate and provide an optical semiconductor element which has high reliability. The present invention provides a silicone resin composition comprising an organopolysiloxane (A) having at least two alkenyl groups per molecule, a liner organohydrogenpolysiloxane (B-1) which has hydrogen atoms each bonded to a silicon atom at the both terminals and a liner organohydrogenpolysiloxane (B-2) which has a hydrogen atom bonded to a silicon atom at one terminal and a hydroxyl or alkoxy group bonded to a silicon atom at the other terminal, a branched organohydrogenpolysiloxane (C) having at least three hydrosilyl groups per molecule, a catalytic (D), and a condensation catalyst (E). The present invention also provides an optical semiconductor device provided with a cured product thereof.
US08598281B2	Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same An epoxybenzyl-terminated poly(arylene ether) has the structure R—W—R wherein W is a divalent poly(arylene ether) residue terminated with phenolic oxygen atoms, and R is an epoxybenzyl group, wherein each occurrence of R is the same or different. The epoxybenzyl-terminated poly(arylene ether) is formed by reacting a peroxide-containing reagent with a vinybenzyl-terminated poly(arylene ether). Also disclosed is a curable composition including the epoxybenzyl-terminated poly(arylene ether)s, a curing promoter, and, optionally, an auxiliary epoxy resin. The curable composition is useful for the preparation of composites, and in particular, composites used in manufacturing printed circuit boards.
US08598277B2	Polyolefin compositions having improved sealability Polyolefin composition with improved sealability comprising from 70 to 95% of one or more copolymers of propylene with one or more comonomers selected from ethylene, a C4-C8 α-olefin and combinations thereof, where the comonomer, or comonomers, content in (A) is from 5 to 25%, and from 5 to 30% by weight of butene-1 (co)polymer (B) having a flexural modulus of 60 MPa or less.
US08598276B2	Polymers comprising units derived from ethylene and poly(alkoxide) A polymer comprises units derived from ethylene and poly(alkoxide) the polymer having at least 0.15 units of amyl groups per 1000 carbon atoms as determined by 13C Nuclear Magnetic Resonance (NMR).
US08598264B2	Adhesive compositions Adhesive compositions suitable for use as tie-layer adhesives in multi-layer films and sheets are provided. The adhesive compositions contain an olefin polymer base resin, a modified polyolefin and a paraffinic liquid hydrocarbon.
US08598258B2	Tire rubber composition and pneumatic tire The present invention provides a tire rubber composition which improves in fuel economy, processability, adhesion, and rubber strength in a balanced manner, and a pneumatic tire. The tire rubber composition includes: a rubber component; a plasticizer (a); and at least one of a resin and a plasticizer (b), the resin being at least one selected from the group consisting of aromatic petroleum resins, terpenic resins, and rosin resins. The plasticizer (a) has a glass transition point of −50° C. or lower. The resin and the plasticizer (b) each have a glass transition point of −40° C. to 20° C. The tire rubber composition includes, for each 100 parts by mass of the rubber component, 1 to 30 parts by mass of the plasticizer (a) and 1 to 30 parts by mass in total of the at least one of the resin and the plasticizer (b).
US08598256B2	Multifunctional biocomposite additive compositions and methods Biocomposite compositions and compositions, which include dried distillers solubles, and which can be used in making biocomposite compositions are described. Methods for preparing the compositions are also described.
US08598254B2	Binding method of water absorbent resin Aqueous liquid and moisture vapor are added to water absorbent resin powder so that particles of the water absorbent resin powder are bound. Supplying the aqueous liquid and moisture vapor to the water absorbent resin powder reduces the amount of particles that remain unbound (ungranulated) and increases the concentration of the water absorbent resin bound particles to provide improved drying efficiency and to obtain particulate water absorbent resin having excellent properties even when the bound particles are highly concentrated. The present invention provides (i) a method for binding water absorbent resin and (ii) a method for producing particulate water absorbent resin including the step of binding particles of water absorbent resin powder.
US08598252B2	Compressible and highly flexible plugging agent A compressible and highly flexible plugging agent comprises the following components in parts by weight: 70-80 parts of natural rubber, 0.5-1 part of polyacrylamide (PAM), 1.5-3 parts of polyanionic cellulose (PAC), 0.5-1 part of biopolymer XC and 10-15 parts of ultrafine calcium carbonate; and the preparation method thereof comprises the following steps: adding the components in the weight parts into the natural rubber in order according to the common preparing method at normal temperature and pressure, mixing and stirring evenly, drying and then grinding into particles of 0.05-50 mm. The plugging agent is characterized by wide raw material sources, simple process, safe application, high plugging ratio and high compressibility, which is suitable for oil recovering and geological drilling applications.
US08598251B2	Paste-like bone cement A kit is provided based on two pastes designed to produce bone cement with high initial stability and therefore low post-cure. The kit includes a paste A and a paste B, wherein paste A contains (a1) a polymerizable monomer having a pH in water in the range of 5-9, (a2) a filling agent insoluble in (a1), and (a3) a barbituric acid derivative selected from the group consisting of 1,5-disubstituted barbiturates, 1,3,5-trisubstituted barbiturates, and 1,3,5-tetrasubstituted barbiturates, and paste B contains (b1) a polymerizable monomer having a pH in water in the range of 5-9, (b2) a filling agent insoluble in (b1), (b3) a peroxide soluble in (b1), (b4) a heavy metal compound insoluble in (b1) and selected from the group consisting of heavy metal salts and heavy metal complexes, and wherein at least one of the pastes A and B contains a halide salt.
US08598250B2	Photocurable acrylic viscoelastic material composition, acrylic viscoelastic material, acrylic viscoelastic material layer tape or sheet and proceed for producing the same The present invention relates to a photocurable acrylic viscoelastic material composition including: an acrylic monomer mixture containing an alkyl (meth)acrylate as a main monomer component and a polar group-containing vinyl monomer, or a partial polymerization product thereof; a (meth)acrylate compound having at least one isocyanate group within the molecule thereof; and a photopolymerization initiator. The photocurable acrylic viscoelastic material composition of the present invention has, by virtue of the above-described construction, excellent pot life and excellent storage stability, despite containing an isocyanate compound having at least one isocyanate group within the molecule thereof, and further can form an acrylic viscoelastic material excellent in the holding power at high temperatures through photocuring. Also, the acrylic viscoelastic material and acrylic viscoelastic material layer tape or sheet of the present invention is excellent in the holding power at high temperatures.
US08598247B2	Polyurethane elastomers from renewable resources A process is disclosed for preparing a elastomer by contacting under reaction conditions: a) an isocyanate component comprising an isocyanate-terminated prepolymer having an isocyanate (NCO) content of 10 to 30 weight percent where the prepolymer is the reaction product of a stoichiometric excess of one or more di- or poly-isocyanate compounds, collectively referred to hereinafter as isocyanate component, with a first polyol component; b) a second polyol component; and c) an effective amount of a blowing agent to provide a polyurethane elastomer with a density of from 200 to 1200 kg/m3; wherein a) and b) are used at an isocyanate index of from 85 to 115, and at least one of the first polyol composition and the second polyol composition contains at least one hydroxymethyl-containing polyester polyol.
US08598243B2	Macropore-containing polymer foams as insulation materials Polymer foams comprising macropores, the macropores having average cross sections of above 500 nm, are obtainable by reacting one or more epoxy resins with one or more amphiphilic epoxy resin hardeners in water in a phase inversion polymerization, where, during the phase inversion polymerization, but after phase inversion has taken place, a volume increase of the internal voids which form initially, and which are present predominantly as micropores having average cross sections of below 500 nm, is induced such that the fraction of the macropores—relative to the entirety of micropores and macropores present in the polymer foam—at the end of the phase inversion polymerization is above 50% by volume. Polymer foams of the present invention are suitable for use as acoustic insulation materials in means of transport and in industrial and plant construction.
US08598239B2	Anderson-type heteropoly compound-based catalyst compositions and their use conversion of synthesis gas to oxygenates Use a transition metal-containing, Anderson-type heteropoly compound catalyst to convert synthesis gas to an oxygenate, especially an alcohol that contains from one carbon atom to six carbon atoms.
US08598236B2	Emulsion system derived from engkabang fat esters An isotropic or homogeneous emulsion system comprises an oil phase including fat esters of illipe fat and a solubilizer; a non-ionic surfactants; and deionized water; characterized in that the solubilizer is a mixture of polyethyleneglycol-40 hydrogenated castor oil, polysorbate 20 and octoxynol-12.
US08598231B2	Flavoring agents containing bio-derived 1,3-propanediol and its conjugate esters Biodegradable flavoring agent compositions comprising 1,3-propanediol are provided, and the 1,3-propanediol in the composition is biologically derived. The compositions exhibit a lower anthropogenic CO2 emission profile. Also provided are biodegradable flavoring agent compositions comprising an ester of 1,3-propanediol. In these compositions, the ester can have at least 3% biobased carbon.
US08598223B2	Crystalline forms of 4, 4′-[4-fluoro-7-({4-[4-(3-fluoro-2-methylphenyl) butoxy] phenyl} ethynyl)-2-methyl-1H-indole-1,3-diyl] dibutanoic acid, 4,4′-[2-methyl-7-({4-[4-(pentafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid, and 4,4′-[4-fluoro-2-methyl-7-({4-[4-(2, 3, 4, 6-tetrafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid The present invention provides type C crystal of compound I, type B crystal of compound II, or type C crystal of compound III set forth in this specification.
US08598222B2	Method for preparing 1,3,4-substituted pyrazol compounds The present invention relates to a process for preparing 1,3-substituted pyrazole compounds of the formula I in which X is especially a CX1X2X3 group in which X1, X2 and X3 are each independently especially hydrogen, fluorine or chlorine, R1 is C1-C4-alkyl or cyclopropyl, and R2 is hydrogen, CN or a CO2R2a group in which R2a is especially C1-C6-alkyl, comprising the following steps: i) reacting a compound of the formula II with a hydrazone of the formula III where the variables X and R2 in formula II are each as defined for formula I, Y is oxygen, an NRy1 group or an [NRy2Ry3]+Z− group, R3 is OR3a or an NR3bR3c group, and where the variable R1 in formula III is as defined for formula I, R4 and R5 are each independently hydrogen, C1-C6-alkyl, optionally substituted phenyl, where at least one of the R4 and R5 radicals is different from hydrogen, and where R4 and R5 together with the carbon atom to which they are bonded may also be a 5- to 10-membered saturated carbocycle; ii) treating the reaction product obtained with an acid in the presence of water.
US08598217B2	Imidazole derivatives and their use as modulators of cyclin dependent kinases The invention provides compounds of the formula (I): and salts, tautomers, solvates and N-oxides thereof; wherein Q is CH or N; X is N, N+—O− or CR3; Y is N, N+—O− or CR3a; R1 and R2 are independently selected from hydrogen and various substituents as defined in the claims; or R1 and R2 together with the atoms to which they are attached, link to form an optionally substituted carbocyclic or heterocyclic aromatic or non-aromatic ring of 4 to 7 members; R3 is selected from hydrogen and various substituents; and R3a is selected from hydrogen and various substituents as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds. The compounds of formula (I) have activity as inhibitors of CDK kinases and are useful in the treatment of inter alia proliferative diseases such as cancers.
US08598216B1	Ritonavir bis-hydrochloride The invention relates to ritonavir bis-hydrochloride, processes for the preparation of the ritonavir bis-hydrochloride, pharmaceutical compositions containing the ritonavir bis-hydrochloride and made from it, and methods of using the ritonavir bis-hydrochloride to inhibit HIV protease or enhance the pharmacokinetics of compounds which are metabolized by cytochrome P450 3A4.
US08598214B2	Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines N-Substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines are effective at controlling insects.
US08598212B2	Therapeutic agent and preventative agent for alzheimer's disease A therapeutic agent or prophylactic agent for Alzheimer's disease has an effect to inhibit or delay the progress of Alzheimer's disease and exhibits a long-lasting therapeutic effect on Alzheimer's disease even when used for a long period of time. The therapeutic agent or prophylactic agent for Alzheimer's disease includes as an effective ingredient a cyclohexane derivative exemplified by the formula below, or a pharmaceutically acceptable salt thereof or a prodrug thereof.
US08598211B2	Carboxamide compounds and their use as calpain inhibitors IV The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity.The carboxamide compounds are compounds of the general formula I in which R1, R2, R3 R4, R5, m and n have the meanings mentioned in the claims and the description, the tautomers thereof, the hydrates thereof and the pharmaceutically suitable salts thereof. Of these compounds those are preferred wherein R1 is optionally substituted phenyl-C1-C2-alkyl or hetaryl-C1-C2-alkyl, R2 is optionally substituted aryl, hetaryl, aryl-C1-C6-alkyl, aryl-C2-C6-alkenyl or hetaryl-C1-C4-alkyl, R3 is C3-C4-alkyl, C1-C4-haloalkyl, C2-C4-alkenyl, C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl, C3-C6-heterocycloalkyl-C1-C2-alkyl, phenyl-C1-C3-alkyl, pyridin-2-yl-C1-C3-alkyl or 1,3-benzoxazol-2-yl-methyl, R4 and R5 independently of one another are halogen, CF3, CHF2, CH2F, C1-C2-alkyl or C1-C2-alkoxy, and m and n independently of one another are 0 or 1.
US08598205B2	Modulators of cystic fibrosis transmembrane conductance regulator The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
US08598201B2	Polymorphs of 6-(piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride The present invention relates to new crystalline polymorphs of 6-(Piperidin-4-yloxy)-2H-isoquinolin-1-one hydrochloride, processes for their preparation and their use, in particular for the preparation of medicaments.
US08598198B2	Nucleic acid binding dyes and uses therefor The invention provides novel compounds and compositions of Formulas I and II, as well as methods of using them. The compounds can be used, for example, to quantify an amount of double stranded DNA in a sample subjected to nucleic acid amplification, or for real time monitoring of a nucleic acid amplification reaction. The compounds can be provided in a kit, for example, with other reagents and instructions for using the compounds and reagents.
US08598190B2	3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.
US08598189B2	Benzoimidazol-2-yl pyrimidines and pyrazines as modulators of the histamine H4 receptor Benzoimidazol-2-yl pyrimidines and pyrazines, pharmaceutical compositions and methods for H4 receptor activity modulation and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritis.
US08598188B2	Method for predicting therapeutic efficacy of chemotherapy on non-small-cell lung cancer This invention relates to an antitumor agent comprising carboplatin and a combination drug of tegafur/gimeracil/oteracil potassium to be administered to a cancer patient selected according to an expression level of thymidylate synthase gene.
US08598187B2	Arylamide pyrimidone compounds The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: Wherein X, Z, R1, R2, R3, R4, R5, R6, R7, n and m are as defined herein. Also disclosed herein are the methods of preparation of compounds of formula (I), intermediates therefor and their utility in treating a variety of disease conditions.
US08598183B2	Solid state forms of a potent HCV inhibitor This invention relates to novel sodium salt forms of the following Compound (1), and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
US08598182B2	Insecticidal pyrimidinyl aryl hyrdrazones Pyrimidinyl aryl hydrazones are effective at controlling insects.
US08598171B2	Compositions and methods for prevention and treatment of amyloid-β peptide-related disorders The present invention provides methods and compositions for modulating levels of amyloid-β peptide (Aβ) exhibited by cells or tissues. The invention also provides pharmaceutical compositions and methods of screening for compounds that modulate Aβ levels. The invention also provides modulation of Aβ levels via selective modulation (e.g., inhibition) of ATP-dependent γ-secretase activity. The invention also provides methods of preventing, treating or ameliorating the symptoms of a disorder, including but not limited to an Aβ-related disorder, by administering a modulator of γ-secretase, including, but not limited to, a selective inhibitor of ATP-dependent γ-secretase activity or an agent that decreases the formation of active (or optimally active) γ-secretase. The invention also provides the use of inhibitors of ATP-dependent γ-secretase activity to prevent, treat or ameliorate the symptoms of Alzheimer's disease.
US08598169B2	Biaryl compositions and methods for modulating a kinase cascade The invention relates to compounds and methods for modulating one or more components of a kinase cascade. The invention relates to compounds of the formula I: or a pharmaceutically acceptable salt thereof. The compounds of the invention are useful for methods of protecting against or treating hearing loss, osteoporosis, cell proliferative disorders, obesity, diabetes, eye disease, stroke, atherosclerosis, neuropathic pain or hepatitis B.
US08598166B2	Polysubstituted derivatives of 6-heteroarylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof Compounds of formula (I): wherein R1, R2, R3, R4, Het and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.
US08598158B2	Fused tricyclic compounds for the treatment of inflammatory disorders The present invention relates to certain lactam ring-containing compounds of the Formula (I) and pharmaceutically acceptable salts thereof, wherein D, E, X1, R1, R2, R3, R4, R9, and R10 are as herein described. In addition, the invention relates to pharmaceutically acceptable compositions comprising at least one such compound, and methods of using the compounds for treating or preventing various inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma, and chronic obstructive pulmonary disorder.
US08598157B2	5-alkynyl-pyridines 5-alkynyl-pyridine of general formula (I) their use as inhibitors of the activity of PI3Kalpha, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R6 and n have the meanings given in the claims and in the specification.
US08598155B2	Imidazo[5,1-f][1,2,4]triazines for the treatment of neurological disorders The present invention relates to compounds of the Formula and pharmaceutically acceptable salts thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as a method for the treatment of a disease or condition selected from the group consisting of central nervous system disorders, cognitive disorders, schizophrenia, dementia and other disorders in a mammal.
US08598152B2	Co-crystals of tramadol and coxibs The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their uses in pharmaceutical formulations for the treatment of pain.
US08598150B1	Composition and method for affecting obesity and related conditions A composition including an effective amount of a compound including manganese [III] tetrakis (4-benzoic acid) porphyrin (MnTBAP), derivatives or analogs thereof to induce a reduction in body weight of a mammal or to improve insulin sensitivity of an obese mammal. A method including introducing an effective amount of a compound including manganese [III] tetrakis (4-benzoic acid) porphyrin (MnTBAP), derivatives or analogs thereof to a mammal to induce a reduction in body weight or to induce an increase in metabolism or insulin sensitivity of the mammal.
US08598149B2	Optimizing mifepristone levels in plasma serum of patients suffering from mental disorders treatable with glucocorticoid receptor antagonists The present invention provides a method for optimizing levels of mifepristone in a patient suffering from a mental disorder amenable to treatment by mifepristone. The method comprises the steps of treating the patient with seven or more daily doses of mifepristone over a period of seven or more days; testing the serum levels of the patient to determine whether the blood levels of mifepristone are greater than 1300 ng/mL; and adjusting the daily dose of the patient to achieve mifepristone blood levels greater than 1300 ng/mL.
US08598147B2	Synergistic antimicrobial composition A synergistic antimicrobial composition having two components. The first component is a hydroxymethyl-substituted phosphorus compound. The second component is cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride.
US08598145B2	Mitochondrially delivered anti-cancer compounds This invention relates to anti-cancer compounds and to methods for treating or preventing cancer. In one aspect the invention concerns mitochondrially delivered pro-oxidant anti-cancer compounds that generate reactive oxygen species and induce apoptosis of cancerous cells. The delivery moiety can be a lipophilic cation and the pro-oxidant vitamin E analogue, such as α-tocopheryl succinate, α-tocopheryl maleate, α-tocopheryl maleyl amide, or 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)-chroman-6-yloxyacetic acid (α-tocopheryloxyacetic acid).
US08598140B2	Aptamers to β-NGF and their use in treating β-NGF mediated diseases and disorders The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to β-NGF; pharmaceutical compositions comprising such β-NGF aptamers; and methods of making and using the same.
US08598139B2	Lipid formulated dsRNA targeting the PCSK9 gene This invention relates to composition and methods using lipid formulated siRNA targeted to a PCSK9 gene.
US08598138B2	Amphiphilic nucleotide cochleate compositions and methods of using the same The present invention is directed to siRNA-cochleate compositions that include a siRNA that is associated with a cochleate and a positively charged amphiphile. The present invention also includes methods for making and using the compositions provided herein.
US08598130B2	Insecticidal combinations A method of controlling or preventing damage to a plant, which comprises applying on the plant or a surrounding area thereof a combination comprising (I) abamectin, and (II) cyflumetofen, in any desired sequence or simultaneously.
US08598129B2	Topical application of ivermectin for the treatment of dermatological conditions/afflictions Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica milliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.
US08598127B2	Peptides for inhibiting MDM2 function Disclosed are peptides for inhibiting mdm2 (mouse double minute 2) and a pharmaceutical composition comprising the same.
US08598125B2	CDCA1 peptide and pharmaceutical agent comprising the same The present invention provides the peptide of (A) or (B) below, and methods of using the peptide: (A) a peptide including the amino acid sequence of SEQ ID NO: 1 or 2, (B) a peptide which includes the amino acid sequence of SEQ ID NO: 1 or 2, wherein one, two, or several amino acid(s) are substituted, deleted, inserted, and/or added, and wherein the peptide shows killer T cell-inducing activity.
US08598121B2	Variants of C-type natriuretic peptide The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).
US08598118B2	Hepatocyte growth factor mimics as therapeutic agents Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, neurodegenerative disease, diabetes and metabolic syndrome, cancer, and defective wound healing.
US08598117B2	Pesticidal toxins A novel pesticidal toxin that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.
US08598114B2	Antimicrobial compounds The present invention relates to a compound of formula (I) AA-AA-AA-X—Y—Z wherein, in any order, 2 of said AA (amino acid) moieties are cationic amino acids and 1 of said AA is an amino acid with a lipophilic R group, the R group having 14-27 non-hydrogen atoms; X is a N atom, which may be substituted by a branched or unbranched C1-C10 alkyl or aryl group which group may incorporate up to 2 heteroatoms selected from N, O and S; Y represents a group selected from —Ra—Rb—, —Ra—Rb—Rb— and —Rb—Rb—Ra— wherein Ra is C, O, S or N, and Rb is C; each of Ra and Rb may be substituted by C1-C4 alkyl groups or unsubstituted; and Z is a group comprising 1 to 3 cyclic groups each of 5 or 6 non-hydrogen atoms, 2 or more of the cyclic groups may be fused and one or more of the cyclic groups may be substituted; the Z moiety incorporates a maximum of 15 non-hydrogen atoms; and wherein the bond between Y and Z is a covalent bond between Ra or Rb of Y and a non-hydrogen atom of one of the cyclic groups of Z. The invention further relates to formulations containing these compounds and their uses in therapy, particularly as antimicrobial or antitumoural agents.
US08598104B2	Pyrrolidone containing detergent composition A detergent composition comprises a hydrophobic polymer, a sulphonated polyacrylate, a pyrrolidone derivative and an anionic surfactant. The compositions find particular application in dishwashing applications and exhibit reduced tendency for spotting on the articles to be cleaned.
US08598103B2	Method for improving the fuel efficiency of engine oil compositions for large low, medium and high speed engines by reducing the traction coefficient The present invention is directed to a method for improving the fuel efficiency of engine oil compositions for large low, medium and high speed engines by reducing the traction coefficient of the oil by formulating the oil using at least two base stocks of different kinematic viscosity wherein the differences in kinematic viscosity between the base stocks is at least 30 mm2/s, and additizing the composition with one or more detergents.
US08598101B2	Dispersions of polymer oil additives The invention relates to dispersions comprising I) at least one polymer that is effective for mineral oils as a cold extrusion improver and is soluble in oil, II) at least one organic solvent that cannot be mixed with water, III) water, IV) at least one alkanolamine salt of a polycyclic carboxylic acid as a dispersing agent, and V) possibly at least one organic solvent that can be mixed with water.
US08598098B2	Lubricant composition A lubricant composition applicable to a sliding section or sliding member of an automotive internal combustion engine or power transmission apparatus to significantly lower a friction coefficient. The lubricant composition contains a base oil for a lubricating oil, an oxygen-containing organic compound, a diamond nano-particle and a dispersant for the diamond nano-particle.
US08598097B2	Diesel lubricant low in sulfur and phosphorus A low-sulfur, low-phosphorus composition comprising an oil of lubricating viscosity; a substantially nitrogen-free sufurized olefin antiwear agent; a nitrogen-containing dispersant; and an overbased detergent selected from the group consisting of salixarates, saligenins, salicylates, and glyoxylates; containing less than about 0.1 percent by weight phosphorus, less than about 0.5 percent by weight sulfur, and having less than about 1.2% sulfated ash, is useful for lubricating a diesel engine, exhibiting good antiwear performance.
US08598096B2	Precipitated weighting agents for use in wellbore fluids A method of formulating a wellbore fluid that includes precipitating a weighting agent from a solution; and adding the precipitated weighting agent to a base fluid to form a wellbore fluid is disclosed. Fluids and methods of formulating wellbore fluids that contain dispersant coated precipitated weighting agents are also disclosed.
US08598093B2	Cement compositions comprising latex and a nano-particle Methods and compositions are provided that may comprise cement, a nano-particle, latex, and water. An embodiment of the present invention includes a method of cementing in a subterranean formation. The method may include introducing a cement composition into the subterranean formation, wherein the cement composition comprises cement, a nano-particle, latex, and water. The method further may include allowing the cement composition to set in the subterranean formation. Another embodiment of the present invention include a cement composition. The cement composition may comprise cement, a nano-particle, latex, and water.
US08598090B2	Invert emulsion based completion and displacement fluid and method of use A method of cleaning a wellbore prior to the production of oil or gas, wherein the wellbore has been drilled with an invert emulsion drilling mud that forms an invert emulsion filter cake is disclosed. The method may include circulating a breaker fluid into the wellbore, where the breaker fluid includes a non-oleaginous internal phase and an oleaginous external phase, where the non-oleaginous phase includes a water soluble polar organic solvent, a hydrolysable ester of a carboxylic acid, and a weighting agent, and the oleaginous external phase includes an oleaginous fluid and an emulsifier, and where the hydrolysable ester is selected so that upon hydrolysis an organic acid is released and the invert emulsion of the filter cake breaks.
US08598089B2	Methods for synthesis of encoded libraries The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
US08598087B2	Crystalline form of 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-0X0-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naph-thalenecarboxamide Disclosed is a solid form of 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide (Compound 1). Also disclosed are compositions containing a solid form of Compound 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a solid form of Compound 1 or a composition containing a solid form of Compound 1.
US08598083B2	Method for increasing plant growth using the fungus Trichoderma harzianum A novel strain of Trichoderma harzianum called TSTh20-1 is described. TSTh20-1 is useful in promoting plant growth, increasing water use efficiency of plants and in remediation of soil or water.
US08598081B2	Specific delivery of agrochemicals Described is the specific delivery of agrochemicals to plants. More specifically, a targeting agent has at least one binding domain that specifically binds to a binding site on an intact living plant. Such binding domains include a peptide having 4 framework regions and 3 complementarity-determining regions, or fragment thereof, wherein the binding domains bind or retain a carrier onto a plant. Described are binding domains that specifically bind trichomes, stomata, cuticle, lenticels, thorns, spines, root hairs, or wax layer. Further described is a method for delivering agrochemicals to a plant, for depositing agrochemicals on a plant, and for retaining the agrochemicals on a plant, using targeting agents comprising the binding domains, and to a method for protecting a plant against stress or controlling plant growth. Also, described is a method for manufacturing a specifically targeting agrochemical carrier.
US08598080B2	Rice cultivar designated ‘CL131’ A novel rice cultivar, designated ‘CL131,’ is disclosed. The invention relates to the seeds of rice cultivar ‘CL131,’ to the plants of rice ‘CL131,’ and to methods for producing a rice plant produced by crossing the cultivar ‘CL131’ with itself or another rice variety, and to single gene conversions of such plants. The invention further relates to hybrid rice seeds and plants produced by crossing the cultivar ‘CL131’ with another rice cultivar. The invention further relates to other derivatives of the cultivar ‘CL131.’
US08598076B2	Display device, laser transfer printing method and laser transfer color donor sheet A display device includes a thin film transistor substrate, a display layer, a patterned color resist layer, a patterned UV block layer and a transparent protective layer. The thin film transistor substrate has a substrate and a plurality of thin film transistors. The display layer is disposed on the thin film transistor substrate. The patterned color resist layer is disposed on the display layer. The patterned UV block layer is disposed on the patterned color resist layer. The transparent protective layer is disposed on the patterned UV block layer. The present invention also provides a laser transfer printing method for fabricating the color resist layer and the patterned UV block layer.
US08598073B2	Methods of making and using activated carbon-containing coated substrates and the products made therefrom The present disclosure relates to methods of making and using activated carbon-containing coated substrates, and products made therefrom.
US08598071B1	Carbon dioxide sorbents Improved CO2 sorbents comprised of a mesoporous silica functionalized with a polyamine are obtained by the in-situ polymerization of azetidine. Also included herein are processes utilizing the improved CO2 sorbents wherein CO2 is chemisorbed onto the polyamine portion of the sorbent and the process is thermally reversible.
US08598068B2	Photocatalytic composites containing titanium and limestone New photocatalytic product comprising compounds of titanium integrated with limestone. The product is obtained by reacting limestone with a suitable precursor of titanium dioxide in a basic solution, followed by accurately washing the solid obtained, drying it and calcining it. A composite is obtained containing limestone, titanium dioxide and calcium titanate. The composite thus obtained, used as such or in mixture with other components, has shown an unexpectedly high photocatalytic activity.
US08598067B2	Interstitial metal hydride catalyst systems and associated processes Exemplary embodiments of the present invention relate to the processing of hydrocarbon-containing feedstreams in the presence of an interstitial metal hydride containing catalyst comprising a surface, and a Group VI/Group VIII metal sulfide coated onto the surface of the interstitial metal hydride. The catalysts and processes of the present invention can improve overall hydrogenation, product conversion, as well as sulfur reduction in hydrocarbon feedstreams.
US08598064B2	Photocatalytic composites containing titanium and limestone free from titanium dioxide New photocatalytic product comprising compounds of titanium integrated with limestone. The product is obtained by reacting limestone with a suitable precursor of titanium dioxide in a basic solution, recovering the product in particular conditions, drying it and calcining it. By operating in presence of sodium, a composite is obtained substantially free from titanium dioxide, containing limestone and calcium titanate. The composite thus obtained, used as such or in mixture with other components, has shown an unexpectedly high photocatalytic activity.
US08598063B2	Catalyst for Fischer-Tropsch synthesis and method for producing hydrocarbons A catalyst for FT synthesis which, in the FT method, is high in a CO conversion and small in the formation of a gaseous component and can stably perform an FT synthesis reaction and enhance the productivity of hydrocarbons, and a method for producing hydrocarbons using the catalyst, are provided. A catalyst for Fischer-Tropsch synthesis comprising a support containing manganese carbonate as a main component, wherein the support contains at least one metal having an activity to the Fischer-Tropsch reaction; and a method for producing hydrocarbons using this catalyst.
US08598058B2	Zirconia-based material doped with yttrium and lanthanum Sintered bodies containing zirconia-based ceramic materials and partially sintered bodies that are intermediates in the preparation of the sintered bodies are described. The zirconia-based ceramic material is doped with lanthanum and yttrium. The grain size of the zirconia-based ceramic material can be controlled by the addition of lanthanum. The crystalline phase of the zirconia-based ceramic material can be influenced by the addition of yttrium.
US08598055B2	Boroalumino silicate glasses Disclosed are alkali-free glasses having a liquidus viscosity of greater than or equal to about 90,000 poises, said glass comprising SiO2, Al2O3, B2O3, MgO, CaO, and SrO such that, in mole percent on an oxide basis: 64≦SiO2≦68.2; 11≦Al2O3≦13.5; 5≦B2O3≦9; 2≦MgO≦9; 3≦CaO≦9; and 1≦SrO≦5. The glasses can be used to make a display glass substrates, such as thin film transistor (TFT) display glass substrates for use in active matrix liquid crystal display devices (AMLCDs) and other flat panel display devices.
US08598054B2	Woven geosynthetic fabric A woven geosynthetic fabric is disclosed having a first weft yarn, a second weft yarn, and a stuffer pick woven in the weft direction of the fabric. A warp yarn interweaves the first and second weft yarns and the stuffer pick. The first weft yarn and the second weft yarn having different cross-sectional shapes. At least a portion of the fabric has a plurality of weft yarn sets with stuffer picks respectively disposed and woven between the weft yarn sets. Each weft yarn set has two first weft yarns and two second weft yarns. One of the two first weft yarns is adjacent one of the two second weft yarns and stacked on the other second weft yarn. The adjacent second weft yarn is stacked on the other first weft yarn.
US08598050B2	Laser annealing method and apparatus Disclosed are a laser annealing method and apparatus capable of forming a crystalline semiconductor thin film on the entire surface of a substrate without sacrificing the uniformity of crystallinity in a seam portion in a long-axis direction of laser light, the crystalline semiconductor thin film having good properties and high uniformity to an extent that the seam portion is not visually recognizable. During the irradiation of a linear beam, portions corresponding to the edges of the linear beam are shielded by a mask 10 which is disposed on the optical path of a laser light 2, and the mask 10 is operated so that the amount of shielding is periodically increased and decreased.
US08598044B2	Method of fabricating a semiconductor device An intermediate film 222 in a three-layered resist film 225 is formed by the chemical vapor deposition process at a temperature not higher than 300° C., using Si(OR1)(OR2)(OR3)(OR4), where each of R1, R2, R3 and R4 independently represents a carbon-containing group or a hydrogen atom, excluding the case where all of R1 to R4 are hydrogen atoms.
US08598043B2	Methods of forming semiconductor constructions The invention includes methods of forming isolation regions for semiconductor constructions. A hard mask can be formed and patterned over a semiconductor substrate, with the patterned hard mask exposing a region of the substrate. Such exposed region can be etched to form a first opening having a first width. The first opening is narrowed with a conformal layer of carbon-containing material. The conformal layer is punched through to expose substrate along a bottom of the narrowed opening. The exposed substrate is removed to form a second opening which joins to the first opening, and which has a second width less than the first width. The carbon-containing material is then removed from within the first opening, and electrically insulative material is formed within the first and second openings. The electrically insulative material can substantially fill the first opening, and leave a void within the second opening.
US08598040B2	ETCH process for 3D flash structures A method for etching features in a plurality of silicon based bilayers forming a stack on a wafer in a plasma processing chamber is provided. A main etch gas is flowed into the plasma processing chamber. The main etch gas is formed into a plasma, while providing a first pressure. A wafer temperature of less than 20° C. is maintained. The pressure is ramped to a second pressure less than the first pressure as the plasma etches through a plurality of the plurality of silicon based bilayers. The flow of the main etch gas is stopped after a first plurality of the plurality of bilayers is etched.
US08598037B2	Silicon etch with passivation using plasma enhanced oxidation A method of etching a silicon layer through a patterned mask is provided. The method uses an etch chamber in which the silicon layer is placed. The method includes (a) providing the silicon layer having the patterned mask formed thereon, (b) providing an etch gas comprising a fluorine containing gas and an oxygen and hydrogen containing gas into the etch chamber in which the silicon layer has been placed, (c) generating a plasma from the etch gas, (d) etching features into the silicon layer through the patterned mask using the plasma, and (e) stopping the etch gas. The oxygen and hydrogen containing gas contains water vapor.
US08598033B1	Method for forming a salicide layer The present invention provides a method for forming a salicide layer. First, a metal-atom-containing layer is formed on a substrate, a first rapid thermal process (RTP) is then performed to the metal-atom-containing layer to form a transitional salicide layer on a specific region. The metal-atom-containing layer is then removed, a thermal conductive layer is formed on the surface of the transitional salicide layer, and a second RTP is performed on the transitional salicide layer.
US08598032B2	Reduced number of masks for IC device with stacked contact levels A three-dimensional stacked IC device has a stack of contact levels at an interconnect region. According to some examples of the present invention, it only requires a set of N etch masks to create up to and including 2N levels of interconnect contact regions at the stack of contact levels. According to some examples, 2x−1 contact levels are etched for each mask sequence number x, x being a sequence number for the masks so that for one mask x=1, for another mask x=2, and so forth through x=N. Methods create the interconnect contact regions aligned with landing areas at the contact levels.
US08598031B2	Reliable interconnect for semiconductor device A method for forming a semiconductor device is presented. A substrate prepared with a dielectric layer formed thereon is provided. A sacrificial and a hard mask layer are formed on the dielectric layer. The dielectric, sacrificial and hard mask layers are patterned to form an interconnect opening. The interconnect opening is filled with a conductive material to form an interconnect. The conductive material is processed to produce a top surface of the conductive material that is substantially planar with a top surface of the sacrificial layer. The sacrificial layer is removed. The sacrificial layer protects the dielectric layer during processing of the conductive material.
US08598028B2	Gate height loss improvement for a transistor The present disclosure provides a method of fabricating a semiconductor device. The method includes forming a first gate structure over an iso region of a substrate and a second gate structure over a dense region of the substrate. The dense region has a greater pattern density than the iso region. The first and second gate structures each have a respective hard mask disposed thereon. The method includes removing the hard masks from the first and second gate structures. The removal of the hard mask from the second gate structure causes an opening to be formed in the second gate structure. The method includes performing a deposition process followed by a first polishing process to form a sacrificial component in the opening. The method includes performing a second polishing process to remove the sacrificial component and portions of the first and second gate structures.
US08598026B2	Semiconductor device and method of manufacturing the same In a method of manufacturing a semiconductor device, a buried layer is formed in a region of a semiconductor substrate and an epitaxial growth layer is formed on the buried layer and the semiconductor substrate. Trenches are formed in the epitaxial growth layer so as to be arranged side by side in a gate width direction of a transistor to be formed, and so that an entire bottom surface of each trench is entirely surrounded by and disposed in contact with the buried layer. A gate electrode is formed inside and on a top surface of each of the trenches and on a surface of the epitaxial growth layer adjacent to each of the trenches via a gate insulating film. A high concentration source diffusion layer is formed on one side of the gate electrode. A high concentration drain diffusion layer is formed on another side of the gate electrode.
US08598013B2	Method for manufacturing SOI substrate and semiconductor device To provide a method for manufacturing an SOI substrate provided with a semiconductor layer which can be used practically even when a substrate having a low heat-resistant temperature, such as a glass substrate or the like is used. The semiconductor layer is transferred to a supporting substrate by the steps of irradiating a semiconductor wafer with ions from one surface to form a damaged layer; forming an insulating layer over one surface of the semiconductor wafer; attaching one surface of the supporting substrate to the insulating layer formed over the semiconductor wafer and performing heat treatment to bond the supporting substrate to the semiconductor wafer; and performing separation at the damaged layer into the semiconductor wafer and the supporting substrate. The damaged layer remaining partially over the semiconductor layer is removed by wet etching and a surface of the semiconductor layer is irradiated with a laser beam.
US08598006B2	Strain preserving ion implantation methods An embedded epitaxial semiconductor portion having a different composition than matrix of the semiconductor substrate is formed with a lattice mismatch and epitaxial alignment with the matrix of the semiconductor substrate. The temperature of subsequent ion implantation steps is manipulated depending on the amorphizing or non-amorphizing nature of the ion implantation process. For a non-amorphizing ion implantation process, the ion implantation processing step is performed at an elevated temperature, i.e., a temperature greater than nominal room temperature range. For an amorphizing ion implantation process, the ion implantation processing step is performed at nominal room temperature range or a temperature lower than nominal room temperature range. By manipulating the temperature of ion implantation, the loss of strain in a strained semiconductor alloy material is minimized.
US08598001B2	Method for manufacturing twin bit structure cell with hafnium oxide and nano-crystalline silicon layer A method and system for forming a non-volatile memory structure. The method provides a semiconductor substrate and forms a gate dielectric layer overlying a surface region of the semiconductor substrate. A polysilicon gate structure is formed overlying the gate dielectric layer. The method subjects the polysilicon gate structure to an oxidizing environment to cause formation of a first silicon oxide layer overlying the polysilicon gate structure and formation of a second silicon oxide layer overlying a surface region of the substrate. A hafnium oxide material is formed overlying the first and second silicon oxide layers and filling the undercut region. The hafnium oxide material has a nanocrystalline silicon material sandwiched between a first hafnium oxide layer and a second hafnium oxide layer. The hafnium oxide material is selectively etched while a portion of it is maintained in an insert region in a portion of the undercut region.
US08597992B2	Transistor and manufacturing method of the same A transistor is manufactured by a method including: forming a first wiring layer; forming a first insulating film to cover the first wiring layer; forming a semiconductor layer over the first insulating film; forming a conductive film over the semiconductor layer; and performing at least two steps of etching on the conductive film to form second wiring layers which are apart from each other, wherein the two steps of etching include at least a first etching process performed under the condition that the etching rate for the conductive film is higher than the etching rate for the semiconductor layer, and a second etching process performed under the condition that the etching rates for the conductive film and the semiconductor layer are higher than those of the first etching process.
US08597984B2	Modular low stress package technology A method of manufacturing a modular semiconductor subassembly: providing at least one semiconductor subassembly having a modular sidewall element of modular dimensions and a semiconductor substrate base element coupled to the modular sidewall element that has at least one semiconductor element with a layout sized to be accommodated by modular dimensions of the modular sidewall element. If a modular package protective cover is to be used: providing the modular package protective cover configured to accommodate the semiconductor subassembly in accordance with a modular design; securing the semiconductor subassembly in the modular package protective cover to create a modular package assembly; and mounting the modular package assembly to a core, with a base side of the semiconductor substrate base element in contact with the core; otherwise: mounting the at semiconductor subassembly to the core, with the base side of the semiconductor substrate base element in contact with the core.
US08597974B2	Confined resistance variable memory cells and methods Methods, devices, and systems associated with resistance variable memory device structures are described herein. In one or more embodiments, a method of forming a confined resistance variable memory cell structure includes forming a resistance variable material such that a first unmodified portion of the resistance variable material contacts a bottom electrode and a second unmodified portion of the resistance variable material contacts a top electrode.
US08597973B2	Ink for forming thin film of solar cells and method for preparing the same, CIGS thin film solar cell using the same and manufacturing method thereof Discussed are an ink containing nanoparticles for formation of thin film of a solar cell and its preparation method, CIGS thin film solar cell having at least one light absorption layer formed by coating or printing the above ink containing nanoparticles on a rear electrode, and a process for manufacturing the same. More particularly, the above absorption layer includes Cu, In, Ga and Se elements as constitutional ingredients thereof and such elements exist in the light absorption layer by coating or printing an ink that contains Cu2Se nanoparticles and (In,Ga)2Se3 nanoparticles on the rear electrode, and heating the treated electrode with the ink. Since Cu(In,Ga)Se2 (CIGS) thin film is formed using the ink containing nanoparticles, a simple process is used without requirement of vacuum processing or complex equipment and particle size of the thin film, Ga doping concentration, etc., can be easily regulated.
US08597970B2	Hybrid polysilicon heterojunction back contact cell A method for manufacturing high efficiency solar cells is disclosed. The method comprises providing a thin dielectric layer and a doped polysilicon layer on the back side of a silicon substrate. Subsequently, a high quality oxide layer and a wide band gap doped semiconductor layer can both be formed on the back and front sides of the silicon substrate. A metallization process to plate metal fingers onto the doped polysilicon layer through contact openings can then be performed. The plated metal fingers can form a first metal gridline. A second metal gridline can be formed by directly plating metal to an emitter region on the back side of the silicon substrate, eliminating the need for contact openings for the second metal gridline. Among the advantages, the method for manufacture provides decreased thermal processes, decreased etching steps, increased efficiency and a simplified procedure for the manufacture of high efficiency solar cells.
US08597968B2	Active device array substrate An active device array substrate is provided. First, a substrate having a display area and a sensing area is provided. Then, a first patterned conductor layer is disposed on the display area of the substrate. A gate insulator is disposed on the substrate. A patterned semiconductor layer, a second patterned conductor layer and a patterned photosensitive dielectric layer are disposed on the gate insulator, wherein the second patterned conductor layer includes a source electrode, a drain electrode and a lower electrode, the patterned photosensitive dielectric layer covering the second patterned conductor layer includes an interface protection layer disposed on the source electrode and the drain electrode and a photo-sensing layer disposed on the lower electrode. A passivation layer is then disposed on the substrate. After that, a third patterned conductor layer including a pixel electrode and an upper electrode is disposed on the passivation layer.
US08597966B2	Method for producing semiconductor optical device A method for producing a semiconductor optical device includes a first etching step of etching a stacked semiconductor layer with a first mask to form a stripe-shaped optical waveguide, the stripe-shaped optical waveguide including first and second stripe-shaped optical waveguides formed on first and second regions of a substrate, respectively; a step of forming a second mask on the stacked semiconductor layer with the first mask left; and a second etching step of etching the stacked semiconductor layer on the first region with the first and second masks. The second mask has a pattern for forming a mesa structure and includes an opening including first and second opening edges remote from side surfaces of the first stripe-shaped optical waveguide. The mesa structure is formed of the first stripe-shaped optical waveguide in the second etching step. The second stripe-shaped optical waveguide formed in the first etching step has a ridge structure.
US08597965B2	Light-emitting device and electronic device using the light-emitting device An object is to provide a method for manufacturing a light-emitting device including a flexible substrate, in which separation is performed without separation at the interface between the light-emitting layer and the electrode. A spacer formed of a light absorbing material which absorbs laser light is formed over a partition of one of substrates, a coloring layer is formed over the other substrate, and the substrates are bonded to each other with the use of a bonding layer. The light-emitting layer and the electrode which are formed over the spacer are irradiated with laser light through the coloring layer, so that at least the bonding layer among the light-emitting layer, the electrode, the coloring layer, and the bonding layer is melted to form a fixed portion where the bonding layer and the spacer are bonded by welding.
US08597961B2	Method for improving internal quantum efficiency of group-III nitride-based light emitting device A method for improving internal quantum efficiency of a group-III nitride-based light emitting device is disclosed. The method includes the steps of: providing a group-III nitride-based substrate having a single crystalline structure; forming on the group-III nitride-based substrate an oxide layer, having a plurality of particles, without absorption of visible light, size, shape, and density of the particles are controlled by reaction concentration ratio of nitrogen/hydrogen, reaction time and reaction temperature; and growing a group-III nitride-based layer over the oxide layer; wherein the oxide layer prevents threading dislocation of the group-III nitride-based substrate from propagating into the group-III nitride-based layer, thereby improving internal quantum efficiency of the group-III nitride-based light emitting device.
US08597960B2	Semiconductor chip stacking for redundancy and yield improvement A stacked semiconductor chip comprising multiple unit chips contains multiple instances of a first chip component that have a low yield and are distributed among the multiple unit chips. An instance of the first chip component within a first unit chip is logically paired with at least another instance of the first chip component within at least another unit chip so that the combination of the multiple instances of the first chip component across the multiple unit chips constitute a functional block providing the functionality of a fully functional instance of the first chip component. The stacked semiconductor chip may include multiple instances of a second chip component having a high yield and distributed across the multiple unit chips. Multiple low yield components constitute a functional block providing an enhanced overall yield, while high yield components are utilized to their full potential functionality.
US08597953B2	Volatile organic compounds as diagnostic markers in the breath for lung cancer A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di (1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.
US08597949B2	Methods and compositions for modulating RAD51 and homologous recombination The present invention concerns methods and compositions involving inhibitors and enhancers of RAD51, a protein involved in homologous recombination. In some embodiments, the present invention concerns methods for stimulating homologous recombination, which has a number of significant research and clinical applications. In certain other embodiments, there are methods for protecting cells using a compound that enhances RAD51 activity. Such enhancers may also be employed to prevent or reduce damage to cells that may be caused by DNA damaging agents. In other embodiments, there are methods for sensitizing cells to the effects of DNA damaging agents, which can have particular applications for cancer patients. In some embodiments of the invention, the RAD51 enhancer or inhibitor is a small molecule that directly affects RAD51 activity, such as its ability to promote filament formation.
US08597948B2	Cloned biological material medical device and method thereof A medical device, said medical device, comprises: a first component having a non-biological material; a second component having a cloned biological material, said second component being attached to said first component, wherein said first component and said second component are operatively associated in a non-living medical device for at least one of treatment, diagnosis, cure, mitigation and prevention of disease, injury, handicap or condition in a living organism. In another aspect, a method comprises: preparing a cloned biological material from a tissue or an organ; attaching said biological material to a medical device; interfacing said biological material with the non-biological material; providing treatment, diagnosis, cure, mitigation and prevention of disease, injury, handicap or condition in a living organism.
US08597946B2	Enhanced dendritic cells for cancer immunotherapy Described herein are methods of cancer immunotherapy, particularly methods of preparing a population of enhanced dendritic cells and methods of treating cancer using the enhanced dendritic cells.
US08597943B2	Method for improved single cell cloning The present invention relates to methods for the cultivation of a population of cells in a serum free cell culture medium, wherein the population of cells has a cell concentration of less than 100 cells/ml, wherein a serum free cell culture medium containing recombinant albumin and recombinant transferrin is used.
US08597939B2	Method of cell cultures and device for implementing it The invention generally provides a cell culture vessel having at least one first zone and at least one second zone, wherein the first zone is a transfer zone for a culture medium which essentially contains no cells and the second zone is a cell culture zone. The invention further includes methods utilizing the cell culture vessel.
US08597937B2	Reaction apparatus An apparatus 20 for biological or chemical reactions, in particular PCR, includes a heat removal module 22 adapted to receive snugly a reaction vessel 24 in such a manner as to create good thermal conductivity contact between the module and the vessel. The heat removal module 22 is formed of a thermally conductive material having therein a channel 64 adapted for the flow of a coolant liquid. The heat removal module 22 is constructed with an array of receiving stations 62 for the reception of a corresponding array of reaction vessels 24.
US08597933B2	Method of treating a sulphide mineral A copper bioleaching process which makes use of a consortium which contains Leptospirillum ferriphilum and a sulphur oxidising microorganism which is halophilic or halotolerant.
US08597929B2	Liquid starter cultures having an improved storage stability and use thereof Liquid microbial starter culture that retains its initial metabolic activity during storage for extended periods of time. Such liquid starter cultures are useful in the manufacturing of food and feed products. Starter cultures of the invention include culture of lactic acid bacteria, e.g. Lactococcus species.
US08597928B2	Bacteriophage of the siphoviridae family and antibacterial compositions comprising the same The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella enteritidis, Salmonella typhimurium, Salmonella gallinarum and Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella enteritidis or Salmonella typhimurium, Fowl typhoid caused by Salmonella gallinarum, and Pullorum disease caused by Salmonella pullorum, which comprises the bacteriophage as an active ingredient, and an animal feed, drinking water, cleaner, and sanitizer which comprise the bacteriophage as an active ingredient.
US08597926B2	Hydrogenases isolated from Thermococcus SPP., genes encoding the same, and methods for producing hydrogen using microorganisms having the genes The present invention relates to novel hydrogenases isolated from novel hyperthermophilic strains belonging to Thermococcus spp., genes encoding the hydrogenases, and methods of producing hydrogen using strains having the genes. According to the hydrogen production methods of the invention, a large amount of hydrogen can be produced merely by culturing the strains in specific culture conditions. Thus, the methods of the invention have advantages in that they are more economic and efficient than existing hydrogen production methods and can produce hydrogen even at high temperature.
US08597924B2	γ-butyrobetaine hydroxylase originated from Neurospora crassa Disclosed is a polynucleotide encoding γ-butyrobetaine hydroxylate (γ-BBH) originating from Neurospora crassa. Also disclosed are a recombinant vector comprising the polynucleotide, a transformant transformed with the recombinant vector, γ-BBH encoded by the polynucleotide, and a method of preparing L-carnitine, which comprises hydroxylating γ-butyrobetaine using γ-BBH encoded by the polynucleotide.
US08597919B2	Methods and systems for producing ethanol using raw starch and selecting plant material The present invention relates to methods for producing high levels of alcohol during fermentation of plant material, and to the high alcohol beer produced. The method can include selecting plant material. Selecting can include excluding plant material that has been exposed to high temperatures or that has had high moisture content.
US08597917B2	Processing biomass Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed for use in the production of useful products, such as fuels. For example, systems can use biomass materials, such as cellulosic and/or lignocellulosic materials, to enhance the production of a product, e.g., the production of ethanol and/or butanol by fermentation.
US08597916B2	Multimeric oxidoreductases The present invention concerns multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate, said complexes having a dehydrogenase subunit and a cytochrome C subunit. The invention further relates to polynucleotides coding for the multimeric complexes and methods of use thereof.
US08597915B2	Process for the reduction of cinnamaldehyde derivative employing enoate reductases The present invention relates to a novel enzymatically catalyzed method for the production of asymmetric aromatic aldehydes in an aqueous reaction medium containing certain organic co-solvents.
US08597914B2	Method of producing a fermentable sugar Provided herein is a transgenic bacteria engineered to accumulate carbohydrates, for example disaccharides. Also provided is a photobioreactor for cultivating photosynthetic microorganisms comprising a non-gelatinous, solid cultivation support suitable for providing nutrients and moisture to photosynthetic microorganisms and a physical barrier covering at least a portion of the surface of the cultivation support. Devices for the large scale and continuous cultivation of photosynthetic microorganisms incorporating photobioreactors and methods of use are disclosed. Also disclosed are methods of producing fermentable sugar from photosynthetic microorganisms using a photobioreactor of the invention.
US08597910B1	DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells Von Willebrand's Factor (VWF) is produced using an expression vector that includes: 1) a DNA sequence encoding a functional VWF protein; and 2) regulatory DNA capable of effecting expression of that DNA sequence in a host cell transformed with the vector. Restriction fragment length polymorphisms (RFLP's) associated with the VWF gene are identified and used in a probe for determining the source of a VWF gene in a DNA sample. The gene for VWF is localized to the short arm of human chromosome 12 (12p).
US08597906B2	Glycosylation of molecules Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.
US08597905B2	Method of detecting tumor cells by fluorescence signals The invention relates to a method of detecting dividing cells, or cells having the potential of dividing, in a cytological specimen stained using a Papanicolaou staining process, by the detection of a fluorescence signal coming from the membranes of these cells.
US08597904B2	Pharmaceutical compositions for the treatment of conditions responsive to proteasome inhibition The invention disclosed herein generally relates to methods and compositions for inhibiting proteasome activity comprising a syrbactin compound have the structure of Formula (I) or (II).
US08597902B2	Peptide protection against ultraviolet light toxicity Short peptides having biological and therapeutic activity are disclosed. Specifically, the activity of the disclosed peptides is directed to reducing or protecting against mutagen-induced cellular/tissue toxicity (i.e., chemopreventive). For example, the disclosed peptides protect against skin toxicity and/or mutagenesis that occurs from ultraviolet (UV) light exposure. The disclosed peptides also block the activation of certain cell cycle regulatory proteins such as Chk2. An example of such a peptide is Ser-Leu-Tyr-Gln-Ser (SEQ ID NO: 10). The disclosed peptides are also useful for methods of reducing or protecting against cellular toxicity and mutation accumulation that would otherwise occur following mutagen exposure. One such method is drawn to applying a peptide to the skin to prevent or reduce mutagenic damage resulting from UV light (e.g., sunlight) exposure.
US08597901B2	2,5-diketo-L-gluconic acid reductases and methods of use Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
US08597900B2	Compositions and methods for the treatment of cancer Disclosed herein are methods and compositions for the treatment of cancer. In particular, the present invention discloses inhibitors of the Fanconi anemia pathway and methods using same. Such inhibitors are useful in inhibiting DNA damage repair and can be useful, for example, in the treatment of cancer.
US08597896B2	Methods to identify modulators using TAS2R bitter taste receptor Sucralose-binding TAS2R bitter taste receptors have been identified. Novel methods to identify modulators and in particular inhibitors to the bitter taste of sucralose, and an inhibitor, are provided.
US08597895B2	Genes with ES cell-specific expression The invention provides an antibody that specifically binds to (a) a protein having an amino acid sequence depicted in SEQ ID NO:16 or 32 or (b) a protein which has an amino acid sequence of (a), wherein one to several amino acids are deleted, substituted, or added, and which is specifically expressed in an ES cell.
US08597894B2	Determining immunoglobulins in non-blood body fluids of neonatal ungulates Provided is a method for determining immunoglobulins in a neonatal ungulate. The method entails obtaining a sample of oral secretions from the neonatal ungulate and measuring an amount of immunoglobulins in the sample of oral secretions. The method is faster and more convenient than previously available methods for determining immunglobulins in neonatal ungulates, such as neonatal horses and cattle.
US08597891B2	Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligation detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence difference.
US08597886B2	Methods and materials for detecting viral or microbial infections This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of target nucleic acid, methods and materials for detecting the amount of target nucleic acid present within a sample, kits for detecting the presence or absence of target nucleic acid, kits for detecting the amount of target nucleic acid present within a sample, and methods for making such kits are provided.
US08597883B2	Biomarkers for cancer-related fatigue and use thereof Described herein is the identification of genes that are significantly up- or down-regulated in patients suffering from cancer-related fatigue (CRF), providing a means for the diagnosis and treatment of CRF. In particular, provided herein is a method of diagnosing a subject with CRF by detecting expression of at least one gene associated with CRF in a sample obtained from the subject; and comparing expression of the at least one gene to a control. Also described herein is a method of treating a patient with CRF by administering to the subject an agent that alters expression or activity of a gene associated with CRF. Further provided is array that includes a plurality of genes associated with CRF, such as TNFRSF25, SLC6A8, OGT, SNCA, APBA2, CASK, OR2W3, MYL4, IL7R, ARHGEF10 and ITGA6.
US08597882B2	Method and apparatus for conducting an assay The present invention relates to methods and apparatus for conducting nucleic acid sequencing by pyrosequencing. The method comprises the steps of providing a platform having at least one well for containing at least one support surface, and providing at least one support surface within each well, wherein the support surface is adapted to immobilize a first binding partner or selectively immobilize a second binding partner. The method further comprises the steps of binding or immobilizing the first or second binding partner to the support surface and dispensing into each well from a point external of said platform a reagent, wherein after the dispensing step the platform is rotated sufficiently such that any residual or unreacted said reagent is substantially centrifugally removed from each well and/or each support surface, wherein during rotation each support surface is held within each well.
US08597881B2	Modified nucleotides Provided herein is a method for replacing the allyl group in a compound of formula R—O-allyl, R2N(allyl), RNH(allyl), RN(allyl)2 or R—S-allyl with a hydrogen, using a transition metal and one or more phosphine ligands.
US08597880B2	Methods and compositions for identifying increased risk of developing fragile X-associated disorders The present invention provides compositions and methods of identifying a subject as having an increased risk of developing fragile X-associated tremor and ataxia syndrome (FXTAS) or identifying a subject having an increased risk of developing fragile X syndrome (FXS), comprising analyzing messenger RNA (mRNA) transcripts and/or translation products of the antisense gene ASFMR1.
US08597878B2	Device and procedure for automated isolation and purification of nucleic acids from complex starting materials of the users choice A reaction unit containing a bottom part and a top part for pipetting a liquid, wherein the bottom part contains a reaction cavity with a permeable filter grid insert and the top part contains a reaction cavity which can be fixed on said bottom part and contains a cavity or covering for receiving a magnet.
US08597877B2	Polymorphic loci that differentiate Escherichia coli O157:H7 from other strains The present invention relates generally to the field of microbiology and food sciences. More particularly, the inventor has discovered several polynucleotide sequences encoding the gnd gene and corresponding 6-phosphogluconate dehydrogenase (6-PGD) proteins from different strains of Escherichia Coli and polymorphic sequences therein. Novel biotechnological tools, diagnostics, and food screening techniques are provided.
US08597873B2	Method for pattern formation According to one embodiment, a method for pattern formation comprises forming a first pattern on a first region of a processed film, forming a reverse material film, having a photosensitive compound, on the processed film so that the reverse material film covers the first pattern, exposing and developing the reverse material film and processing the reverse material film into a second pattern in a second region different from the first region on the processed film, applying etch-back, after exposing and developing the reverse material film, to the reverse material film to expose an upper surface of the first pattern and processing the reverse material film into a third pattern in the first region, and etching the processed film using the second pattern and the third pattern as masks.
US08597870B2	TARC material for immersion watermark reduction A coating material for use during a lithography process. In an example, a coating material disposed on a material layer includes a polymer and a quencher catcher chemically bonded to the polymer. The quencher catcher substantially neutralizes any quencher that diffuses into the coating material from the material layer.
US08597866B2	Method of producing a carrier for electrophotography and method of producing a developer for electrophotography A method of producing a carrier for electrophotography includes: covering a surface of a core particle with a coating layer including resin particles and a crosslinking resin in an uncrosslinked state present in spaces between the resin particles; and applying a mechanical impact from the outer surface of the coating layer before crosslinking of the crosslinking resin.
US08597865B2	Electrostatic-image-developing toner, electrostatic image developer, image forming apparatus, and image forming method An electrostatic-image-developing toner includes a polyester resin; two or more pigments; a polyethylene wax; and a polyolefin-polyvinyl-based graft copolymer, and satisfies the relationship represented by the following equation (1): 0.2≦wd/wp≦5.0 (1) wherein wp represents a total content (wt. %) of the pigments, and wd represents a content (wt. %) of the polyolefin-polyvinyl-based graft copolymer.
US08597864B2	Photoreceptor for electrophotography, process for producing the same, and electrophotographic apparatus Provided is a photoreceptor for electrophotography, a process for producing the photoreceptor, and an electrophotographic apparatus that includes the photoreceptor. The photoreceptor has a photosensitive layer which contains a resin binder that is a copolymerized polyallylate resin. An electrophotographic apparatus having a photoreceptor drum that includes this photoreceptor has a reduced surface frictional resistance throughout the printing period from the beginning to after printing, thus reducing the amount of surface wear while producing satisfactory images.
US08597863B2	Electrophotographic photoreceptor, method of manufacturing electrophotographic photoreceptor, process cartridge, and image forming apparatus An electrophotographic photoreceptor including a conductive substrate, a photosensitive layer, and a cross-linked resin surface layer comprising a cross-linked resin having a charge transport structure, which satisfies the following inequations: 0.01WRa(LHH) (2-1) WRa(LHL)>WRa(HLH) (2-2) WRa(LHL)>WRa(HML) (2-3) WRa(LHL)>WRa(HMH) (2-4) WRa(LHL)>WRa(HHL) (2-5) WRa(LHL)>WRa(HHH) (2-6) wherein WRa (μm) represents an arithmetic average roughness according to JIS-B0601:2001 of frequency components that are obtained by subjecting a one-dimensional data array of a surface profile of the electrophotographic photoreceptor to a wavelet transformation multiresolution analysis.
US08597860B2	Dummy patterns and method for generating dummy patterns A method for generating dummy patterns includes providing a layout region having a layout pattern with a first density, inserting a plurality of first dummy patterns with a second density corresponding to the first density in the layout pattern, dividing the layout region into a plurality of sub-regions with a third density, adjusting a size of the first dummy pattern according to a difference between the second density and the third density, and outputting the layout pattern and the first dummy patterns on a photomask.
US08597855B2	Electrolyte material, liquid composition and membrane/electrode assembly for polymer electrolyte fuel cell An electrolyte material, which comprises a polymer (H) having ion exchange groups converted from precursor groups in a polymer (F) having repeating units (A) having a precursor group represented by the formula (g1) and repeating units (B) based on a perfluoromonomer having a 5-membered ring, and having a density of at most 2.03 g/cm3, the polymer (H) having an ion exchange capacity of from 1.3 to 2.3 meq/g dry resin: wherein Q1 and Q2 are a perfluoroalkylene group having an etheric oxygen atom, or the like, and Y is F or the like; the electrolyte material being suitable for a catalyst layer of the membrane/electrode assembly; the membrane/electrode assembly being excellent in power generation characteristics under low or no humidity conditions and under high humidity conditions.
US08597854B2	Polymer electrolyte membrane, and membrane electrode assembly and polymer electrolyte fuel cell using the same Disclosed is a fuel cell in which a membrane electrode assembly less undergoes increase in ion conduction resistance, and a polymer electrolyte membrane less undergoes deterioration. Specifically, the polymer electrolyte membrane includes a first membrane and a second membrane being two different membranes composed of polymer electrolytes having different ion-exchange capacities, in which the first membrane has an area of one surface thereof equal to or larger than an area of one surface of an anode or a cathode, and the second membrane has an area of one surface thereof smaller than that of the first membrane and is arranged in a gas inflow region on a side being in contact with the cathode. The second membrane has an ion-exchange capacity smaller than that of the first membrane or has a number-average molecular weight larger than that of the first membrane.
US08597853B2	Electrode catalyst for fuel cell, membrane-electrode assembly for fuel cell including same, and fuel cell system including same An electrode catalyst for a fuel cell including a carbon-based carrier and an active metal supported in the carrier, for example, an electrode catalyst for a fuel cell includes a carrier and an active metal supported in the carrier, wherein the electrode catalyst has an X value of 95 to 100% in Equation 1. X(%)=(XPS measurement value)/(TGA measurement value)×100 [Equation 1] wherein, the XPS measurement value represents a quantitative amount of the active metal present on a surface of the electrode catalyst, the TGA measurement value represents the XPS measurement value using a monochromated Al Kα-ray, which is the quantitative amount of total active metal supported in the catalyst.
US08597852B2	Fuel cell stack having a plurality of modules A fuel cell stack having a plurality of connected modules. Each module includes an elongate hollow member and at least one passage extending through the hollow member. Each hollow member has a first flat surface and a second flat surface arranged parallel to the first flat surface. A first module includes a plurality of fuel cells arranged on at least one of the first and second flat surfaces. A first end of each module has an integral spacer.
US08597845B2	Fuel cell system with heat transferor and fuel tank and method of driving the same A fuel cell system is disclosed. In one embodiment, the fuel cell system includes: i) a fuel tank that contains a fuel in at least a partially liquefied state, ii) a heat-generating unit that generates heat, iii) a heat-transfer unit that is connected between the heat-generating unit and the fuel tank to transport the heat to the fuel tank, and iv) a temperature-regulating unit that regulates a temperature of the fuel tank.
US08597842B2	Fuel cell module A fuel cell module includes a fuel cell stack, a heat exchanger, an evaporator, a reformer, and a combustor for at least heating any of the fuel cell stack, the heat exchanger, the evaporator, and the reformer. The fuel cell module is surrounded by an inner heat insulating layer and an outer heat insulating layer. The inner heat insulating layer is used in a high temperature area, and the outer heat insulating layer is used in a low temperature area. The inner heat insulating layer contains a large amount of metal component in comparison with the outer heat insulating layer.
US08597841B2	Method for generating a gas which may be used for startup and shutdown of a fuel cell The present invention provides a method for generating a gas that may be used for startup and shutdown of a fuel cell. In a non-limiting embodiment, the method may include generating a nitrogen-rich stream; merging the nitrogen-rich stream with a hydrocarbon fuel stream into a feed mixture stream; and catalytically converting the feed mixture into a reducing gas.
US08597837B2	Method for producing nonaqueous electrolyte lithium-ion secondary battery The present invention provides a method for producing a lithium-ion secondary battery with excellent high-temperature storage characteristics. The method for producing the lithium-ion secondary battery provided by the present invention includes a step of assembling a lithium-ion secondary battery using positive and negative electrodes, and a nonaqueous electrolyte containing in an organic solvent a lithium salt as a supporting salt, at least one type of substance selected from carboxylic acid anhydrides and dicarboxylic acids as additive A, and at least one type of substance selected from vinylene carbonate, vinylethylene carbonate, ethylene sulfite, and fluoroethylene carbonate as additive B; a step of carrying out initial charging of the assembled battery to a predetermined voltage; and a step of carrying out an aging treatment by keeping the battery at a temperature of 35° C. or higher for 6 hours or longer.
US08597835B2	Positive-electrode material for a lithium ion secondary battery and manufacturing method of the same Provided is a positive electrode material for a safe, high capacity, long lifetime lithium ion secondary battery capable of large current charging and discharging. The positive electrode material contains between 5% by mass or more and 30% by mass or less of a carbon black composite formed by joining together fibrous carbon and carbon black wherein ash is 1.0% or less by mass in accordance with JIS K 1469 and the remainder includes olivine-type lithium iron phosphate, and volatile oxygen-containing functional groups which constitutes 1.0% or less by mass of the positive electrode material. The fibrous carbon is preferably a nanotube having a fiber diameter of 5 nm or more and 50 nm or less and a specific surface area between 50 m2/g or more and 400 m2/g or less.
US08597825B2	Battery assembly including battery module with wrap blanket between module and encapsulating solution A battery module includes pressure release features for releasing excess pressure in a battery container, a wrap blanket disposed between a module and potting material disposed in a case to secure modules while allowing repair, replacement, recycling and/or reuse of modules and a connector.
US08597817B2	Bipolar battery and plate A bipolar battery plate is utilized for production of a bipolar battery. The bipolar battery plate includes a frame, a substrate, a conductor, a filler, first and second lead layers, and positive and negative active materials. The substrate is positioned within the frame and includes a plurality of perforations that are sealed by a filler, with the conductor positioned in the perforation and held by the filler. The conductor connects to the plurality of perforations. The first lead layer positioned on one side of the substrate, while the second lead layer positioned on another side of the substrate. The first and second lead layers electrically connected to each other through the filler. The positive active material (PAM) positioned on a surface of the first lead layer, while the negative active material (NAM) positioned on a surface of the second lead layer.
US08597816B2	Separator for nonaqueous secondary battery, method for producing the same, and nonaqueous secondary battery The present invention is to provide a separator that is excellent in heat resistance, shutdown function, flame retardancy and handling property. The separator for a nonaqueous secondary battery of the invention is a separator for a nonaqueous secondary battery that has a polyolefin microporous membrane at least one surface of which is laminated with a heat resistant porous layer containing a heat resistant resin, and is characterized by containing an inorganic filler containing a metallic hydroxide that undergoes dehydration reaction at a temperature of 200 to 400° C.
US08597811B2	Rechargeable battery including battery cells with casings having different wall thicknesses A rechargeable battery has a plurality of rechargeable battery cells which are situated in an interspaced manner in a rechargeable battery housing filled at least partially with a filler material which encloses the rechargeable battery cells, with a first rechargeable battery cell including a first casing, and a second rechargeable battery cell including a second casing, such that the first casing and the second casing having different wall thicknesses, at least in sections.
US08597810B2	Battery pack Disclosed herein is a battery pack including: a plurality of cylindrical battery cells; and an electrode tab for electrically connecting terminals of the battery cells arranged in a pattern; wherein the electrode tab is formed with a slit along the longitudinal direction thereof, between fixation parts for fixation to the terminals of the battery cells.
US08597808B2	Battery module A battery module includes a plurality of rechargeable batteries each having a gas exhaust member openable at a threshold pressure; a housing holding the rechargeable batteries and having a gas exhaust hole; and a valve member covering the gas exhaust hole, wherein a pressure for opening the valve member is lower than the threshold pressure.
US08597807B2	Secondary battery including a thermally insulating sheet having a recess for receiving a thermal fuse A battery includes an external terminal, a thermal fuse, a bare cell, an electrode assembly disposed within the bare cell and electrically coupled to the external terminal via the thermal fuse, such that the thermal fuse electrically disconnects the electrode assembly from the external terminal when a temperature of the battery reaches a predetermined value, a top cover, a protective circuit module within the top cover and on the bare cell, and a thermally insulating top sheet disposed on the thermal fuse, between the thermal fuse and the protective circuit module, the top sheet having a recess configured to receive the thermal fuse, such that the top sheet covers the top surface of the thermal fuse.
US08597806B2	Method for operating fuel cells with passive reactant supply A method for operating a passive, air-breathing fuel cell system is described. In one embodiment, the system comprises one or more fuel cells, and a closed fuel plenum connected to a fuel supply. In some embodiments of the method, the fuel cell cathodes are exposed to ambient air, and the fuel is supplied to the anodes via the fuel plenum at a pressure greater than that of the ambient air.
US08597803B2	Light emitting devices and compositions A light emitting composition includes a light-emitting lumophore-functionalized nanoparticle, such as an organic-inorganic light-emitting lumophore-functionalized nanoparticle. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition. In an embodiment, the light emitting device can emit white light.
US08597797B2	Chromium nitride ion-plating coating and its production method, as well as piston ring used for internal combustion engine [Task] The chromium nitride ion-plating coating has a property that it is hard but is liable to peel off. Year by year, the required level of wear resistance and scuffing resistance becomes higher in a diesel engine. The property of a coating is improved to enhance the wear resistance and scuffing resistance and also to improve resistance against peeling off.[Means for Solution] (1) Composition is mainly composed of chromium, nitrogen, and carbon, and the concentration of carbon relative to the total concentration of the main components is from 4 to 8% by weight. (2) The crystal structure is that texture of the CrN (111) plane orientation is from 0.4 to 2.0 in terms of a CrN (111) structural coefficient. (3) Vickers hardness is from Hv 1600 to Hv 2000.
US08597795B2	Antifouling coating composition, antifouling film, composite film, and in-water structure Provided are an antifouling coating composition containing a hydrolyzable resin having a specific silicon-containing group and a triorganosilyl oxycarbonyl group, an antifouling film, a composite film and an in-water structure such as a ship using the same. The hydrolyzable resin may further have a specific metal-atom-containing group containing a divalent metal atom. By the antifouling coating composition, it is possible to form a coating film having excellent crack resistance, while exerting an excellent antifouling property for a long period of time even when no or a small amount of antifouling agent is contained.
US08597791B2	Sensor of an apparatus for determining and/or monitoring a process variable A sensor of an apparatus for determining and/or monitoring at least one process variable. The sensor includes: at least one substrate, which is composed of a substrate material; at least one sensitive layer, which is applied on the substrate and which produces at least one measured variable dependent on the process variable and/or on a change of the process variable; and at least one passivating layer, which is applied on the sensitive layer. The invention provides that the passivating layer consists at least partially of the substrate material.
US08597782B2	Housing and method for making the same A housing is provided which includes an aluminum or aluminum alloy substrate, an aluminum layer and a corrosion resistant layer formed on the aluminum or aluminum alloy substrate in that order. The corrosion resistant layer is an Al—O layer. Then, Nd ions are implanted in the Al—O layer by ion implantation process. The atomic percentages of O in the Al—O gradient layer gradually increases from the side of Al—O gradient layer near the aluminum or aluminum alloy substrate to the other side of Al—O gradient layer, away from aluminum or aluminum alloy substrate. Therefore the housing has a high corrosion resistance. A method for making the housing is also provided.
US08597780B2	Hard coat film A hard coat film excellent in abrasion resistance and saponification resistance. A hard coat layer includes a cured product of a curable resin composition containing a reactive inorganic fine particle having an average particle diameter of 5 nm to 30 nm, and has a skin layer, wherein the reactive inorganic fine particles are localized, in its surface region being an interface and its vicinity on a side opposite to a transparent substrate film side of the hard coat layer. Alternatively, the reactive inorganic fine particle has an average particle diameter of 30 nm to 100 nm, and has density distribution in a thickness direction of the hard coat layer lowest at an interface on a side opposite to a transparent substrate film side of the hard coat layer while the density is highest at an interface and its vicinity on the transparent substrate film side of the hard coat layer.
US08597773B2	Decorative element and plastic part provided with a decorative element A preformed decorative element, which can be injection-overmolded with a plastic material and comprises a transparent plastic foil, on which a decoration is printed. The foil is provided, at least partially on both sides, with a non-surface-covering decoration, the decoration on the inner side being printed with a surface-covering color coating layer.
US08597772B2	Corrugated carbon fiber preform In one example, a method includes mixing a plurality of carbon fibers in a liquid carrier to form a mixture, depositing the carbon fiber mixture in a layer, forming a plurality of corrugations in the carbon fiber layer, and rigidifying the corrugated carbon fiber layer to form a corrugated carbon fiber preform. In another example, a method includes substantially aligning a first ridge on a first surface of a first corrugated carbon fiber preform and a first groove on a first surface of a second corrugated carbon fiber preform, bringing the first surface of the first corrugated carbon fiber preform into contact with the first surface of the second corrugated carbon fiber preform, and densifying the first corrugated carbon fiber preform and the second carbon fiber preform to bond the first corrugated carbon fiber preform and the second carbon fiber preform.
US08597769B2	Etching mask, base material having etching mask, finely processed article, and method for production of finely processed article There are provided an etching mask which has a superior thermal imprinting characteristic and also a good anti-etching characteristic, a base material with the etching mask, a microfabricated product to which those etching mask and base material are applied, and a production method of the microfabricated product. The etching mask formed of a thermoplastic resin containing at least one kind of skeleton expressed by a chemical formula (1) or a chemical formula (2) in a main chain wherein R1, R2, R3, R4, R5, R6, R7, R8 in the formulae (1), (2) can be different or same one another, each of which is a hydrogen atom, a deuterium atom, a hydrocarbon group having a carbon number of 1 to 15, a halogen atom, or a substituent group containing a hetero atom like oxygen or sulfur, and may form a ring structure one another and wherein m and n are integers equal to or greater than 0.
US08597767B2	Optical element, roller type nanoimprinting apparatus, and process for producing die roll To provide an optical element having excellent adhesion to a lamination film, a roller nanoimprint apparatus, and a production method of a mold roller are disclosed. In at least one embodiment of the present invention, an optical element includes a nanostructure film including recesses and protrusions in nanometer size formed continuously on a surface of the nanostructure film and a lamination film laminated on the nanostructure film. The nanostructure film includes a nanostructure-free region free from the recesses and protrusions in nanometer size in both ends along a longitudinal direction of the nanostructure film.
US08597763B2	Element for sealing or reinforcing a cavity and method for introducing a penetrating element into such an element In the case of an element for sealing or reinforcing a cavity of a structural element, in particular of a vehicle, the element comprises a base element a foamable part, and an opening for receiving a penetrating element. A wing is arranged on the base element, the opening is open at the side and an actuator which moves the wing when the penetrating element is introduced is arranged on the wing.
US08597759B2	Graphic having simulated stitching A graphic for application to a textile is disclosed. The graphic includes a front surface configured to be viewable when the graphic is applied to the textile. The graphic further includes a back surface opposite the front surface and configured to contact the textile. The graphic further includes an attachment mechanism, other than stitching, that attaches the graphic to the textile. The graphic also includes a simulated stitching pattern “etched” onto the front surface of the graphic extending around a perimeter of the graphic and includes projections simulating stitch ends.
US08597754B2	Base for turf system A turf underlayment layer for supporting an artificial turf assembly includes a plurality of panels assembled together, each panel being made from a plurality of polyolefin beads bonded together, each panel further including a core, a top side having a plurality of projections, and a bottom side having a plurality of projections, the top projections forming top side water drainage channels and the bottom projections forming bottom side water drainage channels, the panels having edges, with the abutment of the edges of adjacent panels defining a water flow connector slot at the intersection of abutting panels, thereby providing a path for the flow of water from the bottom side water drainage channels of one panel to the bottom side water drainage channels of an abutting panel.
US08597743B2	Aluminum nitride sintered body Provided is an aluminum nitride sintered body with high optical transmissivity and which has a smooth surface in the unpolished condition after firing. The aluminum nitride sintered body has an oxygen concentration of 450 ppm or less, a concentration of impurity elements excluding oxygen, nitrogen, and aluminum of 350 ppm or less, and an average crystal grain diameter of between 2 μm and 20 μm, and also has an arithmetic mean surface height Ra of 1 μm or less and a maximum height Rz of 10 μm or less in the unpolished condition after firing.
US08597741B2	Insulated glass unit possessing room temperature-cured siloxane sealant composition of reduced gas permeability The invention relates to an insulated glass unit having an increased service life. An outer glass pane and inner glass pane are sealed to a spacer to provide an improved gas impermeable space. The glass unit includes a curable two-part sealer composition which, upon curing, exhibits unexpectedly high adhesion to substrates.
US08597740B2	Red organic light emitting element and display device provided with same, donor substrate and transfer method using same, method of manufacturing display device, and system of manufacturing display device A thermal transfer method for selectively transferring a red organic light material of a transfer layer from a donor substrate to a recipient substrate to form a red organic light emitting element. The donor substrate has a reflecting layer in a planned formation region of the transfer layer and an absorbing layer in a region other than the planned formation region of the transfer layer. The transfer layer is formed on an area on the front face side of the base. The transfer layer in the region where the absorbing layer is formed is selectively removed. the donor substrate and the other substrate are placed in opposition. The transfer layer on the reflecting layer is transferred to the recipient substrate.
US08597738B2	Fabrication of single-crystalline graphene arrays The synthesis of ordered arrays of GSC's by re-growth from pre-patterned seed crystals that offer an approach for scalable fabrication of single crystal graphene devices while avoiding domain boundaries is demonstrated herein. Each graphene island is a single crystal and every graphene island is of similar size. The size of graphene island arrays can be as small as less than 1 mm2 or as large as several m2. The distance between each GSC island is also adjustable from several micrometers to millimeters. All of the graphene islands are addressable for devices and electrical circuit fabrication.
US08597735B2	Electrostatic powder coating method and electrostatic powder coating apparatus Workpieces, which are conveyed by a conveying device along a conveying path, are heated by a heating and degreasing coil. Then, resin powder is downwardly sprayed from a nozzle of a coating device to each corresponding one of the workpieces, which are conveyed by the conveying device. The workpieces are thereafter heated by a heating and curing coil. At each of the heating coils, a dummy member, which is made of an electrically conductive material, is displaced from a retracted position to a forward position, which is located between the corresponding heating coil and a corresponding adjacent part of the conveying path of the conveying device, when an empty one of mount locations of the conveying device reaches the forward position of the dummy member.
US08597729B2	Systems and methods for manufacturing quantum dot-doped polymer microbeads In a method and system for forming microbeads, a polymer solution includes particles and a polymer dissolved in a solvent. A stream of the polymer solution flows into a chamber. A focusing fluid contacts and focuses the polymer stream in the chamber. The focusing fluid and the focused polymer stream flow, as a single flow stream, out from the chamber. Pendant droplets detach from a leading end of the single flow stream to form the microbeads. The focusing fluid reacts with the polymer solution to form functional groups at a surface of the microbeads for binding with biorecognition molecules. In the system, a flow focusing apparatus includes a flow focusing body shaped to define the chamber. Microbeads formed according to the methods and systems are also disclosed.
US08597728B2	Film forming method There is disclosed a film forming method of spraying an aerosol jetted from a nozzle on a film formation object, while continuously changing a spraying position of the aerosol, to form a film which continuously covers an upper surface, an outer surface and a curved surface, which enables continuous formation of a high-quality film by a simple process. This film forming method includes a first film forming step of continuously spraying the aerosol on an upper surface W01 and a curved surface W03 connected to the upper surface W01, to continuously form a film which covers the upper surface W01 and a film which covers at least part of the curved surface W03; and a second film forming step of continuously forming a film which covers an outer surface W02 and a film which further covers the film formed on the curved surface W03 in the first film forming step.
US08597724B2	Corrosion protective coating through cold spray Methods for repairing gas turbine components damaged by corrosion that not only restores the components back to their original dimensions to ensure proper engine operations, but also have the added benefit of mitigating future corrosion attacks thereby extending the useful life of the components.
US08597723B1	Perpendicular magnetic recording medium with single domain exchange-coupled soft magnetic underlayer and device incorporating same A perpendicular magnetic recording disk having a single domain exchange-coupled laminated soft magnetic underlayer (SUL) is disclosed. The SUL is a combination synthetic anti-parallel coupled SUL structure, which has the product (Mst) of saturation magnetization and film thickness of the middle ferromagnetic layer less than the sum of the Mst of the bottom and top ferromagnetic layers. Subjected to a post radial field reset process, this SUL provides single domain state. Moreover, both robustness of stray fields and low permeability are obtained while keeping excellent corrosion resistance and cost effective manufacturability.
US08597722B2	Method for manufacture and structure of multiple electrochemistries and energy gathering components within a unified structure A method for using an integrated battery and device structure includes using two or more stacked electrochemical cells integrated with each other formed overlying a surface of a substrate. The two or more stacked electrochemical cells include related two or more different electrochemistries with one or more devices formed using one or more sequential deposition processes. The one or more devices are integrated with the two or more stacked electrochemical cells to form the integrated battery and device structure as a unified structure overlying the surface of the substrate. The one or more stacked electrochemical cells and the one or more devices are integrated as the unified structure using the one or more sequential deposition processes. The integrated battery and device structure is configured such that the two or more stacked electrochemical cells and one or more devices are in electrical, chemical, and thermal conduction with each other.
US08597718B2	Calcium phosphate ultrathin films and a method for preparing them An ultrathin film of calcium phosphate crystals having a thickness of 200 nm or less on a surface of a solid substrate, and a method for preparing the same are disclosed. Further, an amorphous dendritic extension used as an intermediate material in preparation of the ultrathin film of calcium phosphate and a method for forming the same are disclosed. The ultrathin film of calcium phosphate crystals can be coated on the surface of the solid substrate while substantially maintaining surface roughness of the solid substrate. The method employs calcium phosphate ion solutions at low temperature. The ion solutions are separately applied to the steps of 1) forming granules of amorphous calcium phosphate on a surface of a solid substrate, 2) forming a dendritic precursor matrix of surface crystals around the granule of amorphous calcium phosphate, 3) removing the amorphous granule via dissolution before the amorphous granule is crystallized, and 4) crystallizing the dendritic precursor matrix of surface crystals to form surface crystals and multiplicating the crystals over the surface of the solid substrate, thereby forming an ultrathin film of calcium phosphate crystals having a thickness of 200 nm or less.
US08597716B2	Methods to increase fracture resistance of a drug-eluting medical device Methods for increasing the fracture resistance of a polymer stent's drug-polymer coating and scaffolding including applying a coating and crimping using techniques that increase the resistance to fracture in the coating layer and scaffolding and scaffolding.
US08597715B2	Target activated microtransfer A method of removing a target from a biological sample which involves placing a transfer surface in contact with the biological sample, and then focally altering the transfer surface to allow selective separation of the target from the biological sample. In disclosed embodiments, the target is a cell or cellular component of a tissue section and the transfer surface is a film that can be focally altered to adhere the target to the transfer surface. Subsequent separation of the film from the tissue section selectively removes the adhered target from the tissue section. The transfer surface is activated from within the target to adhere the target to the transfer surface, for example by heating the target to adhere it to a thermoplastic transfer surface. Such in situ activation can be achieved by exposing the biological sample to an immunoreagent that specifically binds to the target (or a component of the target). The immunoreagent can alter the transfer surface directly (for example with a heat generating enzyme carried by the immunoreagent), or indirectly (for example by changing a characteristic of the target). In some embodiments, the immunoreagent deposits a precipitate in the target that increases its light absorption relative to surrounding tissue, such that the biological specimen can be exposed to light to selectively heat the target. Alternatively, the immunoreagent is an immunofluorescent agent that carries a fluorophore that absorbs light and emits heat.
US08597713B2	Method for producing hypoallergenic peanut products A peanut food product with reduced levels of allergenic protein Ala h1 is produced by initiating the germination process in raw peanuts, holding the peanuts in moist conditions for a period of time, typically something like 48 hours, roasting the peanuts, and then performing an assay for Ala h1 to verify that a reduced level has been achieved.
US08597710B2	Low-mycotoxin coffee cherry products A coffee cherry is harvested, preferably in a sub-ripe state, and quick-dried to provide a basis for numerous nutritional products. Such coffee cherries and portions thereof may be particularly characterized by their extremely low concentration of mycotoxins, including various aflatoxins, fumonisins, ochratoxins, and/or vomitoxin (DON, deoxynivalenol).
US08597709B2	Dietary supplement and methods of use One aspect of the invention provides dietary fiber compositions comprising effective amounts of glucomannan, xanthan gum, and alginate to produce a desired viscosity. The invention also provides food products comprising an effective amount of a dietary fiber composition. In other aspects, the invention provides methods for preparing a dietary fiber composition or a food product comprising a dietary fiber composition and methods for promoting satiety, promoting weight loss, lowering blood glucose levels, or lowering blood cholesterol levels in a mammal.
US08597703B2	Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component A delivery system for inclusion in an edible composition is formulated to have at least one active component with an encapsulating material for delivering the active component upon consumption of the edible composition.
US08597698B2	Formulations for treatment of skin disorders The Present Invention teaches herbal formulations based on a non-aqueous extract of wrightia tinctoria and an extract of cocos nucifera, which, when applied topically and used as directed in therapeutically effective amounts, have been clinically proven to be safe and effective for people needing treatment for skin conditions such as reducing or regressing dermal tortuosity, reducing spongiform pustules, and reversing and regressing stratum granulosum in keratinization disorders. The formulations can take the form of an ointment, an oil, a soap, or a shampoo.
US08597695B1	Herbal combinations for treatment of a skin condition A method and medicine for treating melanoma, BCC (basal cyr carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, comprising applying or injecting to an infected skin area of a patient diagnosed with melanoma, BCC (basal cyr carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, a treatment regimen that includes periodic doses of a molecular combination of emodin and digoxin and/or an herbal combination of Da Huang and Sheng Di Huang.
US08597694B2	Stabilized oleosome preparations and methods of making them The physical stability of oleosomes is preserved in a composition by introducing a multihydric alcohol and an acid that can reduce the pH of the composition of less than 6. The resultant composition can be useful in the manufacture of cosmetic, food, and pharmaceutical products, among others.
US08597691B2	Anti-hypothermia composition An anti-hypothermia composition is provided, in particular an anti-hypothermia composition that prevents hypothermia caused by general anesthesia during surgical operations. The composition prevents hypothermia by preventing the decrease in the biological function of patients and correcting acidosis. Specifically, the anti-hypothermia composition is a preparation containing a bicarbonate ion and provided in the form of an infusion fluid. The infusion fluid preferably contains sodium bicarbonate as a major component that serves as a source of the bicarbonate ion, along with each or a combination of other electrolytes, glucose and amino acids.
US08597690B2	Pharmaceutical composition A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.0 parts by weight precipitated calcium carbonate in 30 parts by weight of the composition.
US08597687B2	Methods for determining the orientation of a tissue graft A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.
US08597685B2	Method for production of particles of pharmaceutical substances particles of pharmaceutical substances and the use thereof The invention relates to a method for producing particles with a length-width ratio of less than about 1.4 from a pharmaceutical substance, which method includes the following stages, that is: (a) provision of a melt of the pharmaceutical substance; (b) production of droplets of the melt by spraying into a processing chamber; (c) repeated guiding of solid particles past sprayed droplets in the processing chamber with the aid of a process gas jet which is guided in a defined way and whose temperature is fixed, depending on the solidification point of the melt, so that at least some of the droplets come into contact with particles and solidify thereon; (d) removal of particles from the processing chamber as a function of the particle size. The invention further relates to particles of pharmaceutical substances and the use thereof.
US08597683B2	Modified release tranexamic acid formulation A modified release dosage form for the oral administration of tranexamic acid.
US08597680B2	Microtablets for drug delivery Methods and systems are provided for making a drug microtablet. The method includes loading a lyophilization capillary channel with a liquid drug solution; lyophilizing the liquid drug solution in the lyophilization capillary channel to produce a lyophilized drug formulation; compressing the lyophilized drug formulation in the lyophilization capillary channel, or in a compression capillary channel, to form a microtablet; and ejecting the microtablet from the lyophilization capillary channel or compression capillary channel. The methods and systems may provide drug microtablets having improved content uniformity and reduced weight variability.
US08597679B2	Fine-particle crosslinked polyvinylpyrrolidone as tablet disintegrant Use of crosslinked polyvinylpyrrolidone with an average particle size of 5-60 μm and a hydration capacity of greater than 7 g/g as tablet disintegrant.
US08597678B2	Nanolipidic particles Nanolipidic Particles (NLPs) having average mean diameters of 1 nm to 20 nm are made from a precursor solution. NLPs can be loaded with a desired passenger molecule. Assemblies of these particles, called NLP assemblies, result in a vehicle population of a desired size. Single application or multifunction NLP assemblies are made from the loaded NLPs and range in size from about 30 to about 200 nm. A method of using preloaded NLPs to make larger carrier vehicles or a mixed population provides increased encapsulation efficiency. NLPs have application in the cosmetics, pharmaceutical, and food and beverage industries.
US08597674B2	In situ blood vessel and aneurysm treatment Treatment of aneurysmal blood vessels with local delivery of therapeutic agents thereby reduces or lessens the severity of an aneurysm, and, where used in conjunction with the placement of an excluding device, provides for more rapid recovery of the blood vessel from any disturbance occurring during placement of the excluding device. Therapeutic agents are placed in the aneurysmal site in a time-release carrier medium, such that the therapeutic agent is released into the aneurysmal site over a period of time without the need to provide systemic introduction of the therapeutic agent. The carrier may be introduced through the patient's dermis, such as with the use of a laparoscope, or intravascularly, through the use of a catheter. The carrier may be in a solid matrix, viscous liquid or liquid form.
US08597669B2	Cosmetic transparent gel preparation and gelling agent A cosmetic transparent gel preparation that has high levels of transparency and hardness and favorable usability, as well as a gelling agent that is ideal for use in the cosmetic transparent gel preparation. The cosmetic transparent gel preparation contains an esterification reaction product obtained by reacting glycerol with a dibasic acid of 18 to 28 carbon atoms and a fatty acid of 8 to 28 carbon atoms (excluding dibasic acids), 12-hydroxystearic acid, and an oil component. The gelling agent contains an esterification reaction product obtained by reacting glycerol with a dibasic acid of 18 to 28 carbon atoms and a fatty acid of 8 to 28 carbon atoms (excluding dibasic acids), and 12-hydroxystearic acid.
US08597668B2	Clear carrier compositions for lipophilic compounds, and method of treating keratinous substrates using such compositions The present invention relates to a composition comprising: (a) at least one alkoxylated polyamine; (b) at least one organic acid chosen from alkyl acids, alkoxylated monoacids, and mixtures thereof; (c) at least one lipophilic compound; and (d) at least one solvent comprising water. Such a composition is clear in appearance, and stable.The present invention also relates to a method of making such a clear composition, and to a method of cosmetic treatment of a keratinous substrate using such a composition.
US08597666B2	Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby A pharmaceutical formulation of compounds with low aqueous solubility and method of manufacture thereof. The formulation may include a pharmacologically active compound having low aqueous solubility and starch in the amount of greater than about 25 weight percent. A manufacturing method may include blending the active compound and starch, compressing the blend into a solid, comminuting the solid into granules, wetting the granules, drying the granules, and tabletting the dried granules to make a solid pharmaceutical formulation.
US08597664B2	Endogenous adjuvant molecules and uses thereof Methods of modulating the immune response using pharmaceutical compositions containing crystalline adjuvants are described. In various embodiments the crystalline adjuvants are selected from the group consisting of monosodium urate (MSU), xanthine, basic calcium phosphate (BCP), calcium pyrophosphate dihydrate (CPPD), hydroxyapatite, calcium oxalate, cholesterol, lipid liquid, other crystalline lipids, lithium heparin, talc, and starch.
US08597663B2	Polysaccharide immunogens from Clostridium difficile The application relates to Clostridium difficile cell surface polysaccharides, compositions comprising Clostridium difficile cell surface polysaccharides, and includes kits, methods and uses thereof.
US08597656B2	Process for the production of immunogenic compositions The present invention relates to a process for producing immunogenic polypeptides, comprising reducing disulfide bonds and blocking the resulting free thiol group with a blocking agent. The immunogenic peptides comprise a fragment of MAGE A3.
US08597654B2	Adjuvant therapy with an anti-ERBB2 antibody conjugated to a maytansiniod The present application describes adjuvant therapy of nonmetastatic breast cancer using an anti-ErbB2 antibody conjugated to a maytansinoid.
US08597652B2	Multispecific anti-HER antibodies The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
US08597650B2	Methods for treating rheumatoid arthritis with anti-bile salt-stimulated lipase (BSSL) antibodies It provides methods and pharmaceutical compositions comprising antagonists to the protein Bile Salt-Stimulated Lipase (BSSL) for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. It further relates to pharmaceutical compositions comprising BSSL antagonists and their use in methods for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. Suitable BSSL antagonists to be used according to the invention are BSSL antibodies.
US08597646B2	Methods and compositons featuring TGF-beta antagonists for the treatment of marfan syndrome and associated disorders The instant invention provides methods and compositions for the treatment and prevention of Marfan syndrome and related diseases, disorders and conditions. The invention further provides pharmaceutical compositions and kits for the treatment and prevention of Marfan syndrome and related diseases, disorders and conditions.
US08597640B2	Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging The present invention provides methods for improving cognitive function, improving mood, and decreasing aggression in a normal adult subject, and in a subject having symptoms characteristic of a neurological disorder, by administration of a nutriceutical formulation of the invention to the subject. The invention additionally features methods of treating neurological disorders, depression, and aggression using nutriceutical formulations. Nutriceutical compositions and formulations for use in the methods of the invention, and kits containing nutriceutical compositions and formulations, are also provided.
US08597638B2	Zinc-enriched biomass, method for the preparation thereof and pro-biotic, cosmetic, dietary and nutraceutic products comprising the same The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
US08597635B2	Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof The present invention relates to interferon-α2b modified with Y-shaped branched polyethylene glycol (PEG) at a single Lys residue and the preparation thereof. The peglated IFN-α2b can be used for the preparation of a medicament for treating a disease, e.g. viral infections such as Hepatitis C.
US08597626B2	Long wear, waterproof mascara composition with water washability The present invention is directed to a long wear, washable and waterproof eye makeup composition having a unique texture and feel including (a) at least one sugar silicone surfactant; (b) at least one oil-soluble polar modified polymer; and (c) at least one oil-soluble high carbon polar modified polymer.
US08597616B2	Dry powder drug delivery formulations, methods of use, and devices therefore The present disclosure relates to systems, methods, and formulations for the pulmonary administration of one or more therapeutic agents, in dry powder form, in a single, large dose quantity. These formulations, methods, and systems are useful in the treatment of patients suffering from toxic or harmful gas exposure, such as nerve gas exposure, as well as in the treatment of patients suffering from diseases of the pulmonary system, including tuberculosis, cystic fibrosis, and chronic obstructive pulmonary disease (COPD).
US08597612B2	Method for producing DDR zeolite Disclosed is a method for producing a DDR zeolite, which can be carried out using materials that are less harmful to the environment. The method for producing a DDR zeolite has a short hydrothermal synthesis time and does not require continuous agitation of the raw material solution. Specifically disclosed is a method for producing a DDR zeolite, which comprises: a raw material solution preparation step in which a raw material solution that contains 1-adamantaneamine, silica (SiO2) and water at a molar ratio 1-adamantaneamine/SiO2 of 0.002-0.5 and a molar ratio water/SiO2 of 10-500 but does not contain ethylenediamine is prepared; and a crystal growth step in which hydrothermal synthesis is carried out while having the raw material solution and a DDR zeolite powder in contact with each other, so that crystals of DDR zeolite are grown using the DDR zeolite powder as a seed crystal.
US08597606B2	Filmy graphite and process for producing the same A process for producing a filmy graphite includes the steps of forming a polyimide film having a birefringence of 0.12 or more and heat-treating the polyimide film at 2,400° C. or higher.
US08597605B2	Purification of single walled carbon nanotubes by dynamic annealing A method for removing impurities from carbon nanotubes is described. Impurities may be removed from the carbon nanotubes by exposing the carbon nanotubes to a temperature, and controlling the temperature such that the temperature is constantly increasing to remove at least a portion of the impurities from the carbon nanotubes.
US08597604B2	Tricalcium phosphates, their composites, implants incorporating them, and methods for their production Methods for the synthesis of tricalcium phosphates are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the tricalcium phosphate precursor precipitate. Particulate tricalcium phosphate compositions having an average crystal size of about 250 nm or less are provided. Compositions of the invention can be used as prosthetic implants and coatings for prosthetic implants.
US08597603B2	Decomposition/elimination method using a photocatalytic material The present invention provides a new method for decomposing and/or removing hazardous substances using a photocatalytic material. The method of the present invention is sufficiently useful in fields requiring quick decomposition and/or removal of hazardous substances in gas and/or liquid phases. The decomposition method of the present invention using a photocatalytic material enables significantly efficient and rapid decomposition of hazardous substances in gas and/or liquid phases by causing a photocatalytic material to coexist with a dilute hydrogen peroxide solution.
US08597602B2	Vacuum truck scrubber system A system and method scrub a vapor. In one embodiment, a vacuum truck scrubber system includes a liquid vat. The liquid vat comprises liquid. The system also includes a first carbon canister. The liquid vat is connected to the first carbon canister. The first carbon canister contains carbon. In addition, the system includes a second carbon canister. The first carbon canister is connected to the second carbon canister. The second carbon canister contains carbon. In addition, the system includes a third carbon canister. Moreover, the system includes that a vapor comprising contaminants is fed to the liquid vat and is introduced from the liquid vat to the first carbon canister wherein a portion of the contaminants are removed from the vapor. The vapor is introduced from the first carbon canister to the second carbon canister wherein another portion of the contaminants are removed from the vapor.
US08597601B2	Selective base metals leaching from laterite ores A process to use ferric sulphate equilibrium to reduce overall acid consumption and iron extraction, the process comprising the steps of: (i) sulphating; (ii) selective pyrolysis and (iii) selective dissolution.
US08597596B2	Liquid handling plunger for a biological sample in a tube A plunger for mixing a biological sample with a reagent in a tube is moved up and down reciprocally to agitate the biological sample and the reagent for subsequent extraction of the material from the mixture to be analyzed. The plunger's agitation facilitates the concentration of the extracted material to reach an extent where a correct analysis is possible. The plunger of the present invention has a shape of a hollow cylinder with an aperture at the bottom, a plurality of slots formed on the cylindrical surface, and an opening formed at the top. The plunger allows a pipette to draw the extracted material in the test tube out from the opening at the top of the plunger without removing the plunger, and prevents drawing out the fragments of the sample after the biological sample and the reagent have been sufficiently mixed.
US08597590B2	Systems and methods for multiple analyte detection Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.
US08597588B1	Sanitizing headsets during a period of non-use Apparatus and method for sanitizing headsets during a period of non-use by placing the headsets on a support construct in the form of a rack within which there is a source of ultraviolet radiation. The headsets are mounted straddling the rack, resiliently gripping the rack to be secured in place, and the rack with mounted headsets is enclosed within a case. The source is activated to pass ultraviolet radiation through the rack to impinge upon the headsets, during a timed duration of operation, with the case automatically locked closed for that duration, thereby sanitizing the headsets. Reflective surfaces within the case serve effectively to immerse the headsets within ultraviolet radiation for the duration of operation, and air is circulated within the case, passing through the rack, during the sanitizing operation to assure complete sanitization of the headsets.
US08597584B2	Gas purifying process and device This gas purifying process removes trace constituents from a mixed gas that includes a rare gas and nitrogen as main components, and at least one from among hydrogen, nitrogen and hydrogen reaction products, and water vapor as the trace constituent. This process sequentially carries out an adsorbing step for removing water vapor and nitrogen and hydrogen reaction products; a hydrogen oxidation step for converting the hydrogen into water vapor by means of a hydrogen oxidation catalytic reaction in the presence of oxygen; and a drying step for removing water vapor generated in the hydrogen oxidation step. When nitrogen oxides are included as a trace constituent, then a denitration step is carried out prior to the adsorbing step, to convert nitrogen oxides into nitrogen and water vapor by means of a catalytic denitration reaction in the presence of a reducing substance.
US08597581B2	System for maintaining flame stability and temperature in a Claus thermal reactor A system may include a sulfur recovery unit. The sulfur recovery unit may include an acid gas supply, which may supply acid gas, an oxygen supply, which may supply oxygen, a fuel supply, which may supply fuel. The fuel may have a higher heating value than the acid gas. Also, the sulfur recovery unit may include a thermal reaction zone, which may thermally recover sulfur from the acid gas by combustion of the fuel and the acid gas with the oxygen and through reaction of the acid gas with combustion products arising from the combustion.
US08597579B1	Molecularly imprinted polymer-denuder based sensors A molecularly imprinted polymer denuder sensor that includes a trapping solution; a delivery device transporting the trapping solution; a denuder operatively connected to the trapping solution and contacting ambient air, wherein the denuder infuses the sample into the trapping solution; a molecularly imprinted polymer sensor operatively connected to the denuder, wherein the MIP sensor captures and detects the threat material; an excitation source operatively connected to the MIP sensor and having an excitation band, wherein the excitation band excites europium (or other signal transducing lanthanide or metal ion) in the MIP when it is bound to the threat material providing unique emission band(s); and an analytical device operatively connected to the MIP sensor, wherein the analytical device senses the presence of the threat material in the sample.
US08597578B2	Optical sensor of bio-molecules using thin-film interferometer The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer.
US08597569B2	Self-sterilizing user input device Technologies are described herein for providing sterilization of a touchscreen or other tactile input surface of a user input device. A self-sterilizing user input device includes a touchscreen for receiving tactile user input and an ultraviolet (UV) light source that emits UV light onto a touchscreen at a sterilization wavelength. A controller selectively activates and deactivates the UV light source according to whether a user is at or near the user input device. According to one aspect, the user input device includes a backlight to illuminate the touchscreen. The UV light source is positioned with the backlight to provide the UV light from a rear side of the touchscreen.
US08597566B2	Non-shortening wrapped balloon A non-shortening catheter balloon having a longitudinal axis and an inflatable balloon able to be affixed to a catheter shaft is provided. The balloon has an uninflated length which remains relatively unchanged upon inflation and is formed of least two helically oriented wrapped passes of balloon materials at a balanced force angle. Methods of making this balloon are also provided.
US08597565B2	Method for forming microscopic 3D structures A method for forming microscopic 3D structures. In the method according to the invention a substrate (105) is placed in a Scanning Electron Microscope (SEM). The SEM is equipped with a Gas Injection System (GIS) (110) for directing a jet of precursor fluid to the substrate. The substrate is cooled below the freezing point of the precursor gas so that a frozen layer of the precursor gas can be applied to the substrate. By now repeatedly applying a frozen layer of the precursor to the substrate and irradiate the frozen layer with an electron beam (102), a stack of frozen layers (130) is built, each layer showing an irradiated part (131) in which the precursor is converted to another material. After applying the last layer the temperature is raised so that the unprocessed precursor (132) can evaporate. As a result 3D structures with overhanging features can be built.
US08597562B2	Composite products and methods of making the same A process comprising: placing a preform stack in a cavity of a molding tool; the preform stack comprising a fiber mat, and at least a first veil underlying the fiber mat, and a first resin impregnating at least the fiber mat, and wherein at least a portion of the first resin is cured; injecting a second resin into the cavity of the molding tool and over at least the fiber mat; applying heat and pressure to the preform stack and second resin to cure any uncured portion of the first resin and to cure the second resin to form a composite having a resin layer over the fiber mat as the cosmetic surface.
US08597561B2	Method for producing pneumatic tire An object of the present invention is to provide a method for producing a pneumatic tire, that does not cause an air-in phenomenon between an inner liner and an insulation or carcass by preventing adhesion of an inner liner to a bladder. The method for producing a pneumatic tire according to the present invention includes the following steps. A green tire using, as an inner liner, a polymer composition in which a polymer component contains 100 to 60% by mass of a styrene-isobutylene-styrene triblock copolymer and 0 to 40% by mass of a polyamide-based polymer that contains polyamide in the molecular chain and has a Shore D hardness of 70 or less is prepared. The green tire is mounted in a mold and vulcanized while being pressurized by a bladder. The resultant vulcanized tire is cooled at 10 to 120° C. for 10 to 300 seconds.
US08597559B2	Method of making a shaker screen A shaker screen for attachment to a bed of a shaker includes a screen frame having at least one mesh screen attached to the top side of the screen frame, wherein the screen frame is preferentially bowed prior to attaching the mesh screen to the screen frame.
US08597557B1	Solid-state shear pulverization/melt-mixing methods and related polymer-carbon nanotube composites Methods using solid-state shear pulverization and melt mixing and related polymer-carbon nanotube composites, as can be used to affect various mechanical and/or physical material properties.
US08597556B2	Method for producing long fiber reinforced thermoplastic resin pellets Disclosed is a method for producing long-fiber-reinforced thermoplastic resin pellets, comprising pultruding a plurality of reinforced fiber bundles in a molten thermoplastic resin while twisting the plurality reinforced fiber bundles to form a strand in which the reinforced fibers are coated with the thermoplastic resin, and cutting the strand to a predetermined length to form pellets, wherein the strand is pultruded under the conditions that the melt viscosity of the thermoplastic resin is adjusted such that the melt flow rate is 500 to 1500 g/10 min, and the twisting angle θ of the reinforced fiber bundles with respect to the pultruding direction of the strand is set as follows: 0°<θ≦50°. As a result of this configuration, according to the method for producing long-fiber-reinforced thermoplastic resin pellets, pellets in which reinforced fibers are easily untwisted when the pellets are melted so that the reinforced fibers can be uniformly dispersed in molded articles can be produced with high productivity.
US08597555B2	Method for manufacturing soft, resistant and bulky nonwoven and nonwoven thus obtained The present invention relates to a method for manufacturing nonwoven and nonwoven obtainable by said method. Particularly, the invention relates to a nonwoven provided with improved tactile and absorbent characteristics, which make it suitable for use in the field of surface cleaning, personal hygiene, or formation of garments. The method is based on the use of lobed spunbonded filaments which have been treated by means of thickening means.
US08597554B2	Article of lightweight inorganic agglomerate in form of slab, process of manufacturing the same and resulting panel In a method for manufacturing conglomerate articles in sheet form, a mix comprising the following is prepared: an expanded inert granular material; a filler consisting of hollow inorganic microspheres and a plasticizer (clay, quartz or other powder mineral, cellulose); an aqueous silicon-containing binder. A layer of mix, where necessary coated with a fiberglass meshwork in order to increase the mechanical strength thereof, is deposited on a temporary support and subjected to vacuum vibrocompression. The resultant rough-formed sheet is heated at a controlled temperature so as to cause evaporation of the water present in the mix.A light, sound-absorbing, heat-insulating sheet, rated in Class 0 in terms of fire reaction, suitable to be plastered or painted superficially and used for forming panels and partitions for internal and external use, is obtained.
US08597553B1	Systems and methods for manufacturing bulked continuous filament A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder below about 1.5 millibars; (E) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (F) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.
US08597549B2	Two-photon or higher-order absorbing optical materials for generation of reactive species Disclosed are highly efficient multiphoton absorbing compounds and methods of their use. The compounds generally include a bridge of pi-conjugated bonds connecting electron donating groups or electron accepting groups. The bridge may be substituted with a variety of substituents as well. Solubility, lipophilicity, absorption maxima and other characteristics of the compounds may be tailored by changing the electron donating groups or electron accepting groups, the substituents attached to or the length of the pi-conjugated bridge. Numerous photophysical and photochemical methods are enabled by converting these compounds to electronically excited states upon simultaneous absorption of at least two photons of radiation. The compounds have large two-photon or higher-order absorptivities such that upon absorption, one or more Lewis acidic species, Lewis basic species, radical species or ionic species are formed.
US08597546B2	Process and apparatus for preparing acetylene and synthesis gas The present invention provides a process for preparing acetylene and synthesis gas by partial oxidation of hydrocarbons with oxygen, by first separately preheating the starting gases comprising a hydrocarbon-containing stream and an oxygen-containing stream and then mixing them in a mixing zone and, after they have flowed through the burner block, reacting them in the firing space and then cooling the products rapidly, wherein the surface on the firing space side of the burner block is covered with a purge gas stream and this purge gas stream is introduced through the burner block by means of several bores, where the averaged ratio of effective surface area of the burner block to number of these bores in the burner block for the purge gas stream is within a range from 5 to 100 cm2.
US08597544B2	Method and structure for non-linear optics A compound for non-linear optics for use at 350 nm and below. The compound includes a material for non-linear optics comprising AxM(1-x)Al3B4O12. x is larger than or equal to zero and smaller than or equal to 0.1, A is selected from a group consisting of Sc, Y, La, Yb, and Lu, and M is selected from a group consisting of Sc, Y, La, Yb, and Lu. The compound is free from a molybdenum bearing impurity of at least 1000 parts per million.
US08597542B2	Luminous substances based on EU2+-(co-)doped mixed garnet crystals and production and use thereof The invention relates to luminous substances which contain Eu2+ doping and at least one silicate mineral from the garnet group and/or a mono and/or polycrystalline yttrium-aluminum garnet (YAG) and/or a luminous substance derived from Y3Al5O12 by partial or complete substitution, and to the production and use thereof.
US08597540B2	Compositions for polishing silicon-containing substrates The invention provides chemical-mechanical polishing (CMP) compositions and methods for polishing a silicon-containing substrate. A method of the invention comprises the steps of contacting a silicon-containing substrate with a polishing pad and an aqueous CMP composition, and causing relative motion between the polishing pad and the substrate while maintaining a portion of the CMP composition in contact with the surface of the substrate to abrade at least a portion of the substrate. The CMP composition comprises a ceria abrasive, a polishing additive bearing a functional group with a pKa of about 4 to about 9, a nonionic surfactant with an hydrophilic portion and a lipophilic portion wherein the hydrophilic portion has a number average molecular weight of about 500 g/mol or higher, and an aqueous carrier, wherein the pH of the composition is 7 or less. The method reduces defects on the wafers, particularly local areas of high removal. The method is also useful for polishing dielectric silicon-containing substrates at a high rate relative to semiconductor silicon-containing substrates.
US08597539B2	Chemical mechanical polishing (CMP) polishing solution with enhanced performance This invention relates to a chemical composition for chemical mechanical polishing (CMP) of substrates that are widely used in the semiconductor industry. The inventive chemical composition contains additives that are capable of improving consistency of the polishing performance and extending the lifetime of a polishing pad.
US08597536B2	Perovskite oxide, oxide composition, oxide body, piezoelectric device, and liquid discharge apparatus Disclosed is a non-lead perovskite oxide having a low Curie temperature and high ferroelectricity represented by General Formula (P) given below. (Bix1,Bax2,Xx3)(Fey1,Tiy2,Mny3)O3 (P) (where, Bi and Ba are A-site elements, X is one kind or a plurality of kinds of A-site elements, other than Pb and Ba, with an average ion valence of 2. Fe, Ti, and Mn are B-site elements. O is oxygen. 0
US08597529B2	Method for processing substrate and method for producing liquid ejection head and substrate for liquid ejection head A method for processing a substrate includes preparing a substrate having a first layer on a first surface side thereof, the first layer having a material capable of suppressing transmission of laser light, processing the substrate with laser light from a second surface that is opposite the first surface of the substrate toward the first surface of the substrate, and allowing the laser light to reach the first layer to form a hole in the substrate, and performing etching of the substrate from the second surface through the hole.
US08597525B1	System including a forced air gas-fired fluidized bed combustion chamber for purifying and recirculating potable water as well as for generating electricity Water purification and recycling system having a large reservoir and a small reservoir adapted to provide potable water to a water user structure. After use by the water user structure, wastewater is applied from said water user structure via at least one wastewater path to wastewater treatment apparatus. The wastewater treatment apparatus receives and processes the wastewater using a coal free power plant that operates continuously to produce steam. The wastewater treatment apparatus is also powered by a co-adjuvant gas turbine generator is adapted to generate supplemental steam for the coal free power plant.
US08597522B2	Waste water storage and treatment system and method A multi-chamber basin is sized to collect excess waste water exceeding the processing capacity of a sewage system. In order to disinfect the waste water exceeding the basin capacity, disinfectant is added at a point in the system after the first basin. After the rain event is over and there is excess sewage treatment capacity, the sewage treatment in the multi-chamber basin is returned to the sewage system. By not disinfecting the waste water in the first basin chamber, the overall disinfectant usage can be minimized.
US08597515B2	Purification of oil sands pond water A method of enhancing flux of tailings settling pond water from an oil sands process through a membrane separation system and purifying the water comprising is disclosed. The process comprises the following steps: (a) treating the water with an effective amount of one or more water-soluble cationic polymers, amphoteric polymers, zwitterionic polymers, or a combination thereof; (b) passing the treated water through a membrane separation system; and (c) optionally, passing the permeate from step (b) through an additional membrane separation system.
US08597514B2	Apparatus and method for treating wastewater A water treatment unit includes a mixing chamber surrounding the upper end of a riser containing an impeller. Water can be moved from a body of water up through the riser, and out through laterally directed openings into the chamber adjacent to an air inlet. The water moving out the laterally directed openings of the stand pipe, mixes with air drawn in through the air inlet to oxygenate the water, and the oxygenated water exits the chamber into the body of water through one or more water outlets in the lower portion of the chamber due to the head developed by the inflow of water into the chamber. The outward flow of water from the chamber can cause a toroidal or other desired flow of water within the body of water surrounding the water treatment apparatus.
US08597511B2	Profiled strip and separating assembly formed therefrom A profiled strip for the installation in honeycomb-like separator packages and a honeycomb-like separator package formed by a plurality of profiled strips are described. The profiled strip has two long base sides and two connection sides. It is distinguished by the fact that a single groove connection portion is respectively arranged at the free ends of the connection sides and a single tongue connection portion is respectively arranged at the ends of the base sides that abut the connection sides, or vice versa. By this, corresponding separator packages can be assembled very simple.
US08597510B2	Device of magnetically separating a sample Present invention relates to a device magnetically separating a sample. The preferred material for the device is plastic. The device is a cuboid plate, which consists of one or two bottom sides and at least two lateral sides. The bottom side has wells on it to accommodate magnetic elements, and the magnetic element which is suitable to be accommodated into the wells comprising column shape, half-column shape, or half circular column shape magnetic elements. The magnetic element comprises permanent magnet or electromagnet, and the permanent magnet is selected from the group consisting of alnico, samarium cobalt, neodymium iron boron, or magnetic ceramic materials. The magnetic elements can adsorb the magnetic samples in the micro plate.
US08597509B2	Countercurrent chromatography rotor The present invention describes a method for constructing a spiral tube support apparatus used in countercurrent chromatography, improvements to countercurrent chromatography tube support design, and methods of using the improved countercurrent chromatography apparatus. The spiral tube support apparatus may be constructed by a shape forming process such as a three dimensional printing process that in turn uses a laser sintering technique, and can be made out of any easily formed material. Shape changes on both the tube support and the top improve the performance of the tube support and ease of manufacturing. The improved tube support and new method of creation permit use in both micro or macro scale preparations and use in small or large molecule preparations. In particular, specific solvent systems are described that permit purification of proteins.
US08597508B2	Sol-gel monolithic column with optical window and method of making A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operation due to a lack of or need for end frits. Also, a second type of column includes an optical window (30) for on-column detection.
US08597504B2	Optimizing feed mixer performance in a paraffinic froth treatment process The invention relates to improved bitumen recovery processes and systems. One process provides for operation of a bitumen froth treatment plant at optimum shear rates in the feed pipe carrying the bitumen froth to the froth settling unit. Another process provides for optimizing the design of a bitumen froth treatment plant by optimizing the diameter of the feed pipe to impart an optimum shear rate to the bitumen froth mixture and further optimizing the volume of the feed pipe to impart an optimum residence time for the bitumen froth stream in the feed pipe. An optimal plant design is also disclosed, the plant including optimal diameter and volume of the feed pipe.
US08597503B2	Coal liquefaction system The present disclosure relates to a coal liquefaction system for utilizing a hydrogenated vegetable oil to liquefy coal. The system includes a reactor for exposing a coal to a hydrogenated vegetable oil in the presence of a coal-derived solvent to form a slurry, a heater that elevates the temperature of the slurry in the reactor to facilitate liquefying the coal and liberating a volatile matter, and a centrifuge that separates the insoluble components from the slurry to obtain a de-ashed coal extract, wherein the coal extract is suitable for downstream processing. The system may also include a distillation column that distills the de-ashed coal extract to obtain a pitch. The system may also include a coker that cokes at least one of the de-ashed coal extract and the pitch to obtain a coke.
US08597502B2	Method of manufacturing diesel fuel base stock and diesel fuel base stock thereof Disclosed is a method of manufacturing a diesel fuel base stock improved in low-temperature flowability, including: fractionating in a first fractionator a synthetic oil obtained by Fisher-Tropsch synthesis into at least two fractions of a first middle fraction containing a component having a boiling range corresponding to diesel fuel oil, and a wax fraction containing a wax component heavier than the first middle fraction; hydroisomerizing the first middle fraction by bringing the first middle fraction into contact with a hydroisomerizing catalyst to produce a hydroisomerized middle fraction; hydrocracking the wax fraction by bringing the wax fraction into contact with a hydrocracking catalyst to produce a wax-decomposition component; and fractionating in a second fractionator a mixture of the produced hydroisomerized middle fraction and the produced wax-decomposition component, wherein rectification conditions in the first fractionator and/or rectification conditions in the second fractionator are adjusted to selectively reduce an n-paraffin having 19 or more carbon atoms in a heavy component contained in the diesel fuel base stock. Furthermore, disclosed is a diesel fuel base stock obtained by the manufacturing method.
US08597493B2	Synthetic aviation fuel The invention relates to a Fischer-Tropsch derived aviation fuel, which fuel is used either as a fuel on its own or as a component in an aviation fuel blend, said fuel having an iso:n paraffins mass ratio above 3, at least 0.1 mass % naphthenes, <0.01 mass % polyaromatics, and <0.5 mass % aromatics.
US08597489B2	Method, apparatus and system for flexible electrochemical processing Conventional electrochemical machining process requires fixed shaped tool cathodes, which makes retooling time consuming and expensive. Flexible tool cathodes include elastically deformable cathodes that can deform in two or three dimensions and can adapt to the contour of the workpiece while the workpiece is moving relative to the flexible tool cathode. That is, the flexible tool cathode can perform tracing. Certain flexible tool cathodes can be also used for special configurations such corners and edges. The flexible tool cathodes can be used to polish, finish, or shape the workpiece through electrochemical processes.
US08597486B2	Droplet based miniaturized device with on-demand droplet-trapping, -fusion, and -releasing The present invention refers to a droplet-based miniaturized device with on-demand droplet-trapping, -fusion, and -releasing. The device makes use of different electrical fields for directing droplets into microwells and releasing them from the same. In another aspect, the present invention refers to a system comprising such a microfluidic device and a method of operating it.
US08597482B2	Process for depositing rinsable silsesquioxane films on metals Cleaned metal surfaces are coated with an aqueous anti-corrosion treatment. The anti-corrosion treatment includes an organofunctional silsesquioxane and a fluoro metallic acid such as H2TiF6, H2ZrF6, as well as others and blends. The metal surface can be rinsed immediately after coating, making this anti-corrosion treatment suitable for preparing a metal surface for electrocoating.
US08597481B2	Gas sensor element and gas sensor equipped with the same A gas sensor element with a bottom part is composed of at least a solid electrolyte body of oxygen ion conductivity, a reference electrode, a detection electrode, an electrode protection layer which supports noble metal catalyst, and a heater. The electrode protection layer is composed of a covering layer, a catalyst layer and a poisoning layer. A quantity of the noble metal catalyst supported in the electrode protection layer at the bottom part of the gas sensor element is larger than that in the electrode protection layer at a leg part of the gas sensor. The bottom part of the gas sensor element has a high temperature rising speed more than the leg part when the heater generates heat energy.
US08597479B2	Sputtering system A magnetron sputtering system generates a high density plasma on a target by applying magnetic fields intersecting an electric field by using a plurality of magnets that are rotatably supported. The respective magnets are revolved and rotated so that the time variation of regions where a magnetic field (line of magnetic force) generated by the each magnet is orthogonal to an electric field is prevented from becoming monotonous. Further, the respective magnets are arranged to make the distances between the center of rotation and the center of revolution of the respective magnets different from each other, so that the regions where the magnetic field (line of magnetic force) generated by the each magnet is orthogonal to the electric field are dispersed in the radial direction of a target.
US08597476B2	Electrolyzer having radial flowing passage Electrolytic equipment in the form of radiation mode that is provided with pluralities of baffles (13) in the form of radiation mode on the top surface of the seat (10) and acidic water passage (131) is formed between the baffles (13). The top surface of the seat (10) has through holes (14) used to make anode conduction portions (33) of anode plate (30) through. In the center of the seat (10), there is a socket joint portion (11) that is provided with an inlet and outlet interval tube (15) in the center of it. There are plurality of equidistributed baffles (151, 157) on the inside wall and the outside wall of the inlet and outlet interval tube (15) to form raw water inlet passage (152) and acidic water outlet passage (153). There are protuberant ribs (16) for separating water inside of the seat (10) corresponding to the location for separating water around the anode plate (30) and the cathode plate (40), which are used to separate alkaline water and acidic water electrolyzed from the anode plate (30) and the cathode plate (40). Alkaline water passage (631) is formed on the bottom surface of the lid (60) and the center of lid (60) is provided with alkaline water outlet joint (61).
US08597472B2	Processing materials Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce ethanol and/or butanol, e.g., by fermentation. Hydrocarbon-containing materials are also used as feedstocks.
US08597469B2	Methods and devices for the production of tissue paper, and web of tissue paper obtained using said methods and devices The invention relates to a method for the production of a web of tissue paper, including the steps of: depositing a layer of an aqueous suspension of papermaking fibers on at least one forming fabric; reducing the water content of the layer until the amount in weight of the fibers in the layer is brought up to a first value; wet-embossing the layer in a nip between a pair of embossing rollers; and drying the embossed layer using a drying system to form a web of tissue paper.
US08597467B2	Water-soluble post branched cationic acrylamide polymers and use thereof A cationic copolymer is obtained by the Hofmann rearrangement (also referred to as the Hofmann degradation reaction) in aqueous solution in the presence of an alkaline-earth and/or alkali hydroxide and an alkaline-earth and/or alkaline hypohalide, on a base copolymer comprising at least one nonionic monomer selected from the group comprising acrylamide (and/or methacrylamide), N,N-dimethylacrylamide and/or acrylonitrile The copolymer is branched after the Hofmann rearrangement, in the presence of at least one polyfunctional branching agent, and is soluble in water.
US08597460B2	Adhesion method, and biochemical chip and optical component made by the same An adhesion method capable of strongly adhering two members without using an adhesive and without impairing a fine structure or optical properties of a joining surface, and a biochemical chip and optical component made by the same are provided. The adhesion method includes step A of forming a coating film 13 of a first film compound having a first functional group on a first joining surface 11 of a first member 21, step B of forming a coating film 14 of a second film compound having a second functional group on a second joining surface 12 of a second member 22, and step C of bringing the first joining surface 11 into contact by pressure with the second joining surface 12 while bringing a coupling agent having at least one coupling reactive group that forms a bond by a coupling reaction with the first functional group and the second functional group into contact with the first and second functional groups to form bonds by the coupling reaction.
US08597458B2	Manufacturing method and a manufacturing apparatus for a composite sheet A manufacturing method for a composite sheet which includes: conveying a first continuous sheet in a first direction so as to abut a depressed surface of a mold member; forming an absorbent body by depositing liquid-absorbent particles on a portion of the first sheet proximal to a suction hole of the mold; and joining a second sheet over the first sheet having the absorbent body that is deposited therebetween, the second sheet being continuously transported in the first direction. A plurality of opposed slope members guide the liquid-absorbent particles onto the first sheet located on the mold member. At least one of the plurality of slope members causes the liquid-absorbent particles to reverse their falling direction from an upper slope member.
US08597454B2	Catheter tip assembly A catheter tip assembly (50) is provided with a catheter tip (56) and an inner catheter (54). The catheter tip (56) has a tapered proximal end, an elongate center portion, and a tapered distal end. The inner catheter (54) includes a narrow proximal portion, a narrow elongate center portion (66), and a wide distal end (68). The catheter tip (56) is disposed within the wide distal end (68) of the inner catheter (54). One advantage of the catheter tip assembly is that no proximal-facing edge is formed at the transition between the narrow elongate center portion of the inner catheter and the catheter tip, which may help reduce the risk of the catheter tip snagging on a stent during use.
US08597424B2	Composition and method for forming an aluminum film A composition for forming an aluminum film, comprising a complex represented by the following formula (1) and a complex represented by the following formula (2), the molar ratio of the complex represented by the following formula (1) and the complex represented by the following formula (2) being 40:60 to 85:15: AlH3.NR1R2R3 (1) AlH3.(NR1R2R3)2 (2) (in the above formulas (1) and (2), R1, R2 and R3 are each independently a hydrogen atom, alkyl group, cycloalkyl group, alkenyl group, alkynyl group, aryl group or aralkyl group.).
US08597422B2	Pigment and filler and a method of manufacturing it The present invention relates to a light, biodegradable, organic pigment and filler, and a method of manufacturing it. According to the present invention, a solution comprising a starch derivative is first prepared by dissolving the starch derivative into a suitable solvent, and, after that, the solution is brought into contact with a non-solvent to precipitate the starch derivative from the solvent, and, as a result, a dispersion is obtained, one which comprises a precipitate consisting of starch derivative and a liquid phase formed of the solvent and the non-solvent, after which the solvent is removed from the liquid phase and the precipitate is separated from the non-solvent and recovered. The present invention can be used to manufacture both a product comprising 100-300 nm spherical particles, which is suitable for use as a pigment, and a coral-like, porous product which is particularly suitable as a filler.
US08597421B2	Cellulose resin composition and cellulose resin film Provided are a cellulose resin composition and cellulose resin film which are free from the problem of bleeding even when containing a plasticizer in a relatively large amount.The present invention relates to a cellulose resin composition obtained by adding (A) polyester plasticizer to a cellulose resin, wherein the aforementioned (A) polyester plasticizer is obtained by allowing a polybasic acid and a polyalcohol to react and 80 mol % or more of said polybasic acid is a succinic acid and an adipic acid. The present invention also relates to a cellulose resin film obtained from the cellulose-based resin composition.
US08597418B2	Absorbent, CO2 or H2S reducing apparatus, and CO2 or H2S reducing method using absorbent An absorbent according to the present invention absorbs CO2 or H2S contained in flue gas emitted from a power generating plant such as a thermal plant, and contains three or more amine compounds selected from linear or cyclic amine compounds having a primary amino group, and linear or cyclic amine compounds having a secondary amino group. By way of a synergetic effect of the mixture of these compounds, the absorption speed of CO2 or H2S absorption is improved. A small amount of CO2 contained in a large amount of boiler flue gas can be absorbed efficiently.
US08597415B2	Electric precipitator and air cleaner having the same Disclosed herein are an electric precipitator, which efficiently charges dust particles without lowering dust collecting efficiency, although a velocity of an air current is not uniform, and an air cleaner having the same. The electric precipitator includes a charger unit including at least two charge cells to charge dust particles contained in air, and a collector unit to collect the dust particles charged by the charger unit. The at least two charge cells include a first cell, through which the dust particles pass at a first velocity, and a second cell, through which the dust particles pass at a second velocity different from the first velocity.
US08597413B2	Scrubber with multiple venturis A scrubber removes matter (e.g., particulate, gaseous, or liquid) from a gas stream in order to recover the matter and/or to clean the gas. In particular aspects, the scrubber contains multiple venturis that may provide additional flexibility and increased efficiency. The invention also pertains to related methods.
US08597412B2	CO2 recovery apparatus and CO2 recovery method A CO2 recovery apparatus according to the present invention includes: an absorber (1003) that brings CO2-containing flue gas (1001A) into counter-current contact with CO2 absorbent (1002) to reduce CO2, and a regenerator (1005) that regenerates rich solution (1004) that has absorbed CO2, in which lean solution (1006) having CO2 reduced in the regenerator (1005) is reused in the absorber (1003). The absorber (1003) further includes a CO2 absorbing unit (1010) that recovers CO2 contained in the flue gas (1001A), and the CO2 absorbent (1002) that has absorbed CO2 is extracted from a rich side of the CO2 absorbing unit (1010) to exterior, cooled, and then supplied to a position nearer to a lean side of the absorber (1003) with respect to the position at which the CO2 absorbent (1002) is extracted.
US08597405B2	Self-cleaning electret filter An illustrative filter includes an electret material, which has a long-lasting electric charge, that is at least partially coated or covered with a conductive layer. An optional insulation layer may be disposed over at least part of the conductive layer. If the electret material has a positive charge, then the filter attracts particles with a negative charge, and vice versa. The filter adsorbs the attracted particles until it becomes saturated with particles, at which point the conductive layer is charged to have a polarity that is opposite the built-in polarity of the electret and that matches the polarity of the adsorbed particles. The charged conduction layer repels the adsorbed particles from the filter, cleaning the filter for continued use.
US08597402B2	Device for capturing gas from a produced water stream A flushable device for capturing gas included within a produced-water stream is described. Gas and water pressure coordination is not required. Controls prevent liquid entry to the gas system and prevent gas entry into the water system. A gas/liquid separator receives an inner vessel lower end. A separator inlet receives a combined fluid stream. A liquid line passes into the inner vessel and down into the separator below the inlet so that liquid separated from the combined stream will flow up the liquid line. The gas line extends from the inner vessel upper end. The gas line conveys gas from the inner vessel upper end to a gas collection system. A top float in the inner vessel activates a gas line motor valve. A bottom float in the inner vessel activates the liquid line motor valve and a second gas vent for rapid expulsion of slugs of gas.
US08597401B2	Exhausting method and gas processing apparatus An exhausting method includes determining an exhaust flow rate of a process gas to be a predetermined value that is less than or equal to a gas flow rate corresponding to a maximum process capability of a purification system when the process gas is diluted to a lower explosive limit; calculating a pressure drop amount per unit time to maintain the determined exhaust flow rate of the process gas, based on a relation between the exhaust flow rate and the pressure drop amount per unit time; and evacuating an inside of the chamber to maintain the determined exhaust flow rate, while controlling the pressure through an automatic pressure control valve by setting a target pressure value to be updated as a control value of the automatic pressure control valve at every predetermined time interval so as to achieve a calculated pressure drop amount per unit time.
US08597399B2	Method for thiosulfate leaching of precious metal-containing materials Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
US08597398B2	Method of refining the grain structure of alloys The invention is directed to a method of making liquid metal compositions containing a large number of solid particles per unit volume, without external heat removal, which solid particles act as nuclei for grains when the metal is solidified. A method of forming a metal solid includes the step of partially removing a solute of a liquid metallic solution which is at its liquidus temperature to partially solidify a metal solvent component, thereby forming a solid fraction, wherein there is essentially no reduction in temperature of the liquid metallic solution and solid fraction. The method further includes the step of subsequently lowering the temperature of the liquid metallic solution and solid fraction to solidify the remaining liquid metallic solution and thereby form a solid that includes the solid fraction formed during the step of partial solute removal. In an embodiment, the method further includes turbulence from gas evolution which aids in solid particle formation and grain refinement.
US08597397B2	Production of metal nanoparticles Processes for the production of metal nanoparticles. In one aspect, the invention is to a process comprising the steps of mixing a heated first solution comprising a base and/or a reducing agent (e.g., a non-polyol reducing agent), a polyol, and a polymer of vinyl pyrrolidone with a second solution comprising a metal precursor that is capable of being reduced to a metal by the polyol. In another aspect, the invention is to a process that includes the steps of heating a powder of a polymer of vinyl pyrrolidone; forming a first solution comprising the powder and a polyol; and mixing the first solution with a second solution comprising a metal precursor capable of being reduced to a metal by the polyol.
US08597391B1	Filtration system and method Described are multi-stage drum filtration systems including a primary rotary drum filter stage, at least one passive filter stage, and a main fan configured to create a vacuum on an inlet side of the primary rotary drum filter stage. The multi-stage drum filtration system may also include a HEPA filter stage. A controller may be configured to control a speed of the main fan to maintain an inlet vacuum to the primary rotary drum filter stage that corresponds to an inlet vacuum set point input.
US08597390B2	Air cleaner An air cleaner is provided with a housing having an opening, and a filter. The filter has a frame and an element supported to the frame. The filter is installed in the interior of the housing from the opening of the housing. A second seal surface of a seal ring of the filter is joined to a first seal surface of the housing in a state in which the filter is installed in the housing. A rib-shaped protection portion extending along the first seal surface is provided in the housing. The protection portion protrudes further toward the filter than the first seal surface. A slide protrusion protruding further toward the first seal surface than the second seal surface is provided in the frame of the filter. The slide protrusion can slide on the protection portion.
US08597389B2	Filtration lighting system Disclosed are various embodiments of a filtration lighting system. In one embodiment, the filtration lighting system includes at least one light source, a circulation fan, at least one air filter, and a housing. The housing includes at least one air inlet and is configured to house the light source, the circulation fan, and the at least one air filter.
US08597386B2	Method and system for continuously pumping a solid material and method and system for hydrogen formation A method of continuously providing a pressurized slurry of a solid material and liquid carbon dioxide is disclosed. The method comprises mixing particles of the solid material and particles of solid carbon dioxide in a mixing container and feeding the mixture of the solid material and the solid carbon dioxide to a pump to form a slurry of the solid material and liquified carbon dioxide. Within the pump, the solid carbon dioxide sublimates, forming a gaseous carbon dioxide that subsequently liquefies due to an increase in pressure. The liquid carbon dioxide and the solid material then mix to form the slurry of the solid material and the liquid carbon dioxide. In some embodiments, the pressurized slurry may be used for pipeline transportation of the solid material. A system of producing a continuous pressurized slurry of solid material and liquid carbon dioxide is also disclosed. A method of producing hydrogen is also disclosed.
US08597385B2	Method and apparatus for shielding cooling tubes in a radiant syngas cooler Methods and a system for shielding cooling tubes in a radiant syngas cooler. The heat shields may prevent direct contact between heated syngas and the cooling tubes. The heat shield may be mounted to a header that also attaches to the cooling tubes. The heat shield may also be separated from the cooling tubes or, alternatively, the heat shield may be coated onto the cooling tubes. Furthermore, prolonged exposure to the heated syngas may corrode the heat shield.
US08597383B2	Metal supported silica based catalytic membrane reactor assembly A catalytic membrane reactor assembly for producing a hydrogen stream from a feed stream having liquid hydrocarbons, steam, and an oxygen source through the use of an autothermal reforming reaction, a water-gas-shift reaction, and a hydrogen permeable membrane.
US08597369B2	Equilibrium-point prosthetic and orthotic ankle-foot systems and devices The present invention relates to a system for use in rehabilitation and/or physical therapy for the treatment of injury or disease. The system can enable an amputee to proceed over any surface without overbalancing. In particular the system is self-adapting to adjust the torque moment depending upon the motion, the extent of inclination, and the surface topography.
US08597366B2	Anti-reflux stent An anti-reflux stent includes an extended inner sleeve, a stent surrounding at least a portion of the inner sleeve and a coating that bonds the stent to the inner sleeve whereby the extended inner sleeve can have a cross-sectional thickness that varies along the length of the inner sleeve. The inner sleeve is made of a material having a thickness and/or flexibility such that the distal end not surrounded by the stent collapses under gastric pressure to prevent the contents of the stomach from flowing into an esophagus. Food and liquid can pass through an inner lumen of the inner sleeve to enter a stomach when desired.
US08597363B2	Prosthetic material for replacing at least one portion of the radial glenoid of a radius The prosthetic material for replacing at least one portion of the radial glenoid of a radius includes a plate (2) extended by an endpiece (3) and a set of screws (4) for fastening the plate (2) on the receiving bone material (R). The plate (2) has a planar body (7) extended by an extension (5) forming a portion of the endpiece (3) and having an inner face (5′) extending in a general plane (D) that is angularly offset relative to the plane (P) of the plate body (7). This extension (5) co-operates with a fitted panel (6) forming the other portion of the endpiece (3) and having an outer face (3′) reproducing at least approximately at least a portion of the surface of the radial glenoid of the radius. The fitted panel is secured on the support extension (5) via a slideway structure (11, 13).
US08597362B2	Method and apparatus for force redistribution in articular joints Pathologies of joints arising from improper force distributions are addressed by displacement of targeted connective and muscle tissues surrounding the joint in order to realign force vectors and alter moment arms loading the joint.
US08597359B2	Cervical and lumbar spinal interbody devices Lumbar and cervical interbody or intervertebral devices for implantation between adjacent vertebrae of a spine and/or within intermediary canals of long bones are characterized by a body defining a superior end and an inferior end whose surfaces have serrations or teeth thereon forming anti-backout structures that allow implantation of the body but inhibit removal or backing out therefrom. The one-way structures may extend from the anterior end to the posterior end. The one-way structures may take different shapes but are always configured to allow insertion of the interbody device in an anterior-first manner while preventing and/or inhibiting the interbody device from backing out posteriorly. The various interbody devices may be further characterized by a body defining a cavity that is in communication with the superior and inferior ends of the body and at least one lateral side thereof via openings in the body. Undercuts are formed in the body about the adjacent the openings in order to support bony ingrowth within the void.
US08597356B2	Intervertebral implant A vertebral implant for fusing adjacent vertebrae or for replacing vertebral bodies is disclosed. The implant is a biocompatible metal resorbable or radiolucent implant conforming substantially in size and shape with an end plate of a vertebra. The implant preferably has a wedge-shaped profile to restore disc height and the natural curvature of the spine. The top and bottom surfaces of the implant have areas with a plurality of teeth to resist expulsion and provide initial stability and areas devoid of any protrusions to receive implantation instrumentation. The implant also has a stackability feature. The implant provides initial stability needed for fusion without stress shielding.
US08597354B2	Vertebral implant A vertebral implant has a body extending along a body axis, having a pair of ends, and adapted to be fitted with its ends axially juxtaposed with respective confronting vertebral faces. An inner ring can pivot on one of the ends of the body about a first axis extending transversely of the body axis through the body, and an outer ring can pivot on the inner ring about a second axis extending nonparallel to the first axis transversely of the body axis through the inner ring and body. The outer ring has an end face adapted to engage the respective vertebral face.
US08597352B2	Articular cartilage fixation device and method An articular cartilage fixation device and method for repairing and regenerating diseased or injured soft tissue such as articular cartilage of the knee, hip, shoulder, and the like. A cartilage flap or cartilage repair device is retained within the chondral or osteochondral defect for a sufficient amount of time such that the cartilage repair device can perform its function and facilitate an appropriate healing response. A plurality of biocompatible anchors are attached to a plurality of flexible members and are shaped to seat into the tissue beneath or near the defect such that the cartilage flap is retained within the defect.
US08597351B2	Holding device for an intraocular lens, packaging and transport means for an intraocular lens, injector device for an intraocular lens as well as method for packaging an intraocular lens and method for loading an intraocular lens into an injector device The invention relates to a holding device for an intraocular lens, characterized in that the holding device has an elongated support member open to the bottom, on which an elongated holding rail for holding the lens is disposed. The invention also relates to an injector device for an intraocular lens as well as to a packaging and transport device for the intraocular lens. Furthermore, the invention relates to a method for packaging an intraocular lens as well as to a method for loading an intraocular lens into an injector device.
US08597349B2	Collapsible/expandable prosthetic heart valves with non-expanding stent posts and retrieval features A frame structure for a collapsible and re-expandable prosthetic heart valve. The frame structure includes an annular annulus portion that is configured for implanting in or near a patient's native heart valve annulus. This annulus portion of the frame structure may include a plurality of annularly spaced commissure post structures interconnected by connecting structures. The commissure post structures may be more resistant to annular collapse than the connecting structures. In the case of a prosthetic aortic valve, the frame structure may also include an annular aortic portion. The aortic portion may include a plurality of attachment points (for tethers) closest to the annulus portion. Such attachment points and tethers can facilitate re-collapse of a partly deployed valve in the event of a need to reposition or remove the valve.
US08597338B2	Intracerebral probe and device for the treatment of neurological or psychiatric dysfunctions An intracerebral probe (11) comprising a first part (20) with laser or cryogenic treatment means and further comprising a hollow second part (22) surrounding the first, the first part sliding inside the second part along its longitudinal axis (A); and a plurality of detectors (16) distributed along a portion of the second part (22) in such a manner as to be capable of identifying a brain dysfunction zone along the longitudinal axis (A) of the second part. Advantageously, the probe presents a lateral treatment window enabling the action of the treatment means to be directed. The invention also provides a kit and a treatment system including such a probe, and the use thereof of treating cell dysfunctions that give rise to neurological or psychiatric symptoms.
US08597337B2	Joint fusion device A device and method are disclosed for the fusion of joints (particularly finger joints or toe joints) in a bent (or angled) position. In certain embodiments, a device for the fusion of joints preferably allows for one or more of various angled positions, and the particular angle may differ for different joints. The device is preferably a bendable implant device for fusing together bones or a joint.
US08597336B2	Apparatus for discrete tissue anchoring for soft tissue repair and method of use Disclosed herein are devices and methods for securing soft tissue to a rigid structure such as bone. Various directional anchors that allow for increasing the stability the attachment of soft tissue to bone are described. Also described is a delivery system for use with the directional anchors that allows for open surgical or arthroscopic application of one embodiment of the device. A method for repairing rotator cuff tears is also described.
US08597335B2	Craniotomy closures and plugs Strip fasteners and cranial plugs for use in reattaching a skull flap removed during brain surgery and methods of using the same. The strip fasteners are flexible and can be shaped to follow the perimeter contour of the skull flap. The cranial plugs can be used to reattach the skull flap or they can be installed after the skull flap is reattached using the strip fasteners. In some embodiments, the cranial plug(s) and strip fasteners can be installed at the same time. The strip fasteners and cranial plugs are designed to encourage bone growth and healing of the skull flap and they can be used to deliver medication and bone growth enhancement compositions to the surgical site.
US08597334B2	Angulated locking plate/screw interface A system for lockably engaging bone screws into a fixation plate may include a locking fixation plate including a threaded screw hole defined by an inner surface surrounding the threaded screw hole, the inner surface comprising an upper countersink and a threaded portion, the threaded portion comprising a pair of threads arranged in a double helix configuration, and a screw comprising a generally conical head tapering into a generally cylindrical shaft that ends at a tip and a single thread beginning near the tip and extending along the generally cylindrical shaft and onto the generally conical head, a thread height of the single thread being constant over a majority of the generally cylindrical shaft and tapering as the thread extends onto the head.
US08597331B2	Prosthetic spinous process and method A prosthetic spinous process includes a member and a plurality of crosslinking rods connected to the member at an angle relative to each other, wherein the member includes at least one opening therethrough.
US08597327B2	Method and apparatus for sternal closure A method and apparatus for securing a fractured or sectioned sternum in a patient's body is disclosed. The apparatus can include an attachment member and an adjustable flexible member construct. The attachment member can have a flexible member holder. The adjustable flexible member construct can have first and second ends and a body defining at least one passage portion. The first and second ends can be passed into and through the at least one passage portion via first and second openings associated with the at least one passage portion of the adjustable flexible member construct to form a pair of loops. The attachment member can be configured to be coupled to at least one of the formed pair of loops. The adjustable flexible member construct can be positioned about the sternum and can be reduced to compress the fractured or sectioned sternum.
US08597326B2	Suturing needle A suturing needle, comprising needle tip portion (1) having needle tip (1a), tapered portion (2) continuing to needle tip portion (1), trunk portion (3) continuing to tapered portion (2), and thread attaching portion (4) continuing to trunk portion (3); needle tip portion (1) has circular section continuing to sharp needle tip (1a), angular section continuing to sharp needle tip (1a), circular section continuing to blunt needle tip (1a) or angular section continuing to blunt needle tip (1a): wherein trunk portion (3) has the relations R1≧R2≧R3, when peak (5) or joint portion between the two flat faces has diameter R1, crest of ridges has a roundness of R2, and a valley (7) has roundness R3; and valley (7) is formed to correspond partially to peak (5), and the thickness becomes continuously larger from tapered portion (2) to trunk portion (3).
US08597320B2	Devices and methods for treating vascular malformations A method of filling an aneurysm is described which includes the step of advancing a device through a patient's vascular system to an aneurysm and positioning the device within the aneurysm. The device has a closed mesh structure forming by a plurality of flexible filaments. The device also has a proximal collar and a distal collar with the flexible filaments extending therebetween. The closed mesh structure is movable from a collapsed configuration to an expanded configuration.
US08597313B2	Eccentric abrading head for high-speed rotational atherectomy devices The invention provides a rotational atherectomy device having, in various embodiments, a flexible, elongated, rotatable drive shaft with at least one flexible eccentric enlarged abrading head attached thereto. In other embodiments, the eccentric abrading head is not flexible or partially flexible. At least part of the eccentric enlarged cutting head has a tissue removing surface—typically an abrasive surface. In certain embodiments, the abrading head will be at least partially hollow. When placed within an artery against stenotic tissue and rotated at sufficiently high speeds the eccentric nature of the enlarged cutting head causes the cutting head and drive shaft to rotate in such a fashion as to open the stenotic lesion to a diameter substantially larger than the outer diameter of the enlarged cutting head. Preferably the eccentric enlarged cutting head has a center of mass spaced radially from the rotational axis of the drive shaft, facilitating the ability of the device to open the stenotic lesion to a diameter substantially larger than the outer diameter of the enlarged cutting head when operated at high speeds.
US08597311B2	Absorbable fastener and applying apparatus A surgical fastener apparatus, for securing a surgical mesh material to body tissue including a pair of anchors each having retaining structure formed on an outer surface thereof; and a suture tether interconnecting the pair of anchors to one another. The pair of anchors having a substantially cylindrical body having a conically tapered distal end and a planar proximal end. The retaining structure includes a series of semi-circular angled projections having a planar proximal surface and a tapered distal end, wherein a center of each of the angled projections is spaced a distance from a longitudinal central axis of the body portion. The surgical fastener is made from a bioabsorbable material which reabsorbs into body tissue at an appropriate rate, such as for example, polyglycolic acid and polylactic acid.
US08597299B2	Instrumentation and method for providing surgical access to a spine A system for accessing a spine from a curved postero-lateral approach may include a curved cannula positioned along a curved path from an opening in the skin to a location proximate the spine. A targeting post may be inserted adjacent the spine to determine the location. A peritoneal retractor and a guide member may be first inserted to establish the path between the tissues and fascia, and one or more intermediate cannulas may be temporarily inserted over the guide member to dilate the tissues prior to insertion of the main cannula. An interbody device may be implanted in an intervertebral space through the cannula. An endoscope may be inserted through the targeting post or the cannula. The system may include instruments with shafts which are flexible or are curved to match the curve of the curved cannula, including a rongeur, curette, rasp, distractor, trial implant, probe, tamp, and implant inserter.
US08597295B2	Surgical instrument with non-contact electrical coupling A surgical instrument includes a reusable base component including a handle and an electrically activatable modular component removably coupled to the base component. The modular component includes an end effector operable from the handle to treat tissue. The end effector is responsive to manipulation of the handle. A first energy storage component is disposed onboard the base component and is electrically coupled to a source of electricity. A second energy storage component is disposed onboard the modular component and is electrically insulated from the first energy storage component. The second energy storage component is arranged such that a current may be selectively induced in the modular component by delivery of electrical energy to the first energy storage component.
US08597292B2	Electrosurgical pencil including improved controls The present disclosure relates to electrosurgical devices having a plurality of hand-accessible variable controls. An electrosurgical device configured for connection to a source of electrosurgical energy is provided and includes a housing; an electrical circuit supported within the housing, the electrical circuit being connectable to the source of electrosurgical energy; and a controller slidably supported on the housing, wherein the controller is configured to exert a force on the electrical circuit to affect a change in the electrical circuit and to exert a force on a surface of the housing to provide a tactile feedback to a user of the electrosurgical device as the controller is moved relative to the housing.
US08597289B2	Cervical opening sealing devices A device for sealing a cervical opening includes a support structure, and a seal coupled to the support structure, the seal having a surface for abutting against tissue next to the cervical opening, wherein the seal is tiltable relative to the support structure. A device for sealing a cervical opening includes a support structure, and a member coupled to the support structure, wherein the member is inflatable to create a seal for abutting against cervical tissue. A device for sealing a cervical opening includes a seal having a surface for contacting tissue next to the cervical opening, an opening formed on the surface of the seal, and a vacuum port, wherein the opening is in fluid communication with the vacuum port.
US08597286B2	Device, system and method for in-vivo cauterization Devices, systems and methods for in-vivo cauterization. An autonomous in-vivo device may include a heating mechanism to cauterize in-vivo tissue. A system may include an autonomous in-vivo heating device having a heating mechanism to cauterize in-vivo tissue, and an in-vivo imaging device to acquire in-vivo images.
US08597285B2	Cryoprobe for low pressure systems A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.
US08597278B2	Medicament delivery system and process A system and method for delivering a substance to a selected site in an alimentary canal of a human or animal includes an ingestible capsule. The capsule has a compartment for storing the substance; a receiver suitable for receiving a signal through animal tissue; a processor for storing a programmed set of instructions; and an electronic power source. The system and method further has at least one transmitter, disposed on a medically relevant site on a body of the human or animal, for sending the signal to the receiver. The receiver includes a proximity based detector for measuring proximity of the receiver to the at least one transmitter, and the processor instructs a releasing device of the capsule to release the substance upon recognition of a pre-programmed pattern of signals.
US08597270B2	Automated filling systems and methods Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.
US08597269B2	Reservoir seal retainer systems and methods At least one tab may extend through at least one opening in a retaining member configured to cover at least a portion of a head of a reservoir body and a portion of a septum supported by the head of the reservoir body. A retaining member may be configured to cover at least a portion of a first head of a reservoir body and a portion of a septum supported by the first head of the reservoir body, and the reservoir body may have a second head having at least one tab. A retaining member located in a head of a reservoir body may be for retaining a septum on the head of the reservoir body, and the head of the reservoir body may have at least one tab.
US08597263B2	Lotion application compartment A lotion application compartment (10) includes an apparatus for topical application of a fluid to a human or animal body. The apparatus includes a spray nozzle (20) and a support (80) for the body. The apparatus further comprises of one or more of the following: a structure for moving the support, so as to change the distance between the body and the spray nozzle (20); a structure for varying the spray pattern, spray pressure, spray frequency and/or spray duty cycle of the nozzle (20); a structure for varying the rotational speed of the support (80); and a structure for raising the body's skin temperature directly by radiation. A lotion application compartment (10) consisting of apparatus for topical application of a fluid to a human or animal body, the apparatus comprising a spray nozzle (20) and a support (80) for the body. The apparatus further includes of one or more of the following: a structure for moving the support, so as to change the distance between the body and the spray nozzle (20); a structure for varying the spray pattern, spray pressure, spray frequency and/or spray duty cycle of the nozzle (20); a structure for varying the rotational speed of the support (80); and a structure for raising the body's skin temperature directly by radiation.
US08597262B2	Apparatus and methods of treatment of pathologic proliferative conditions uterine tissue A uterine fibroid treatment device providing for localized delivery of one or more treatment drugs for treating various uterine conditions including, for example, uterine fibroids, abnormal uterine bleeding, pelvic adhesions and endometriosis. Generally, the uterine treatment device comprises a physical positioning element that can be inserted, positioned and maintained in close proximity to the uterine tissue to be treated. The treatment drugs delivered to the treatment location can include various combinations of anti-proliferative agents and angiogenesis inhibitors to provide different treatments concurrently. In some embodiments, the physical element can also serve the dual purpose of delivering the treatment drugs while simultaneously cutting off blood flow to a mature fibroid to initiate hypoxic/ischemic conditions within the mature fibroid.
US08597258B2	Valved catheter A valved catheter is provided which includes a slit that opens readily in both directions either when a fluid is caused to flow from the interior to the exterior thereof or when a fluid is caused to flow from the exterior to the interior thereof, and that prevents inadvertent closure thereof from the opened state. The valve includes an openable slit that penetrates from the inner surface to the outer surface of a distal end section of a valved catheter with a closed distal end, and edge portions on the two sides of the slit are formed along the direction in which the valved catheter extends. The slit includes a linear shape in the cross-section of the distal end section of the valved catheter that extends in a position away from a center line “c” that passes through the center of the valved catheter in parallel with this center line “c” whereupon, either one of the edge portions deforms more readily than either one of the other edge portions.
US08597257B2	Drug delivery device A novel device and method for intradermal delivery of an active agent is provided. The device comprises a housing which contains a reservoir chamber. A flexible reservoir containing the active agent is placed in the chamber. Upon pressure on an actuator the active agents is delivered via a hollow needle to the skin.
US08597256B2	Seal member A seal member is configured to seal a chamber of a drug delivery device which is suitable to contain a drug, wherein the seal member comprises a diaphragm.
US08597254B1	Medical line securement system The present invention is a protective sleeve for containing medical lines, comprising: (a) a foldable sleeve comprising first and second side panels, and adapted to be opened and closed along its longitudinal axis so as to form a conduit for medical lines, at least one of the panels being transparent, the foldable sleeve adapted to be reversibly opened along its longitudinal axis, and having releasable closures to maintain the foldable sleeve in a folded closed position; and (b) a plurality of rigid members incorporated into the sleeve and along the longitudinal axis.
US08597252B2	Removable flash chamber A needle hub and catheter assembly are disclosed herein. The needle hub includes an introducer needle having a lumen extending therethrough. A needle hub is coupled to a proximal end of the introducer needle. A flash chamber is removably coupled to the needle hub or the introducer needle. An interior of the flash chamber is in fluid communication with the lumen of the introducer needle when the flash chamber is coupled to the needle hub or the introducer needle. As such, the flash chamber can collect a sample of blood that can be accessed when the flash chamber is removed. In some instances, the blood can also be dispensed from the flash chamber into a test strip or other testing device.
US08597251B2	Pleated trocar shield A surgical access device or trocar defines an access channel for instruments extending from a proximal end to the distal end thereof. The trocar comprises a cannula and a seal assembly disposed at the proximal end of the cannula. The seal assembly comprises a first or zero seal, a second or instrument seal, and a trocar shield disposed proximally of the first seal and the second seal. The first seal seals the access channel in the absence of an instrument extending therethrough. The second seal seals the access channel in the presence of an instrument extending therethrough. The trocar shield protects the first seal and second seal from damage as an instrument is advanced through the access channel. The trocar shield comprises an open proximal end and a tapered distal end comprising a plurality of longitudinal pleats, converging in an opening.
US08597249B2	Catheter assembly and components thereof Catheter assemblies are generally discussed herein with particular discussions extended to catheter assemblies having a tip protector, a valve, a valve opener, and optionally a needle wiper. The valve opener is disposed inside a catheter hub and is configured to be pushed by an IV set luer connector to open a valve following successful catheterization to pass fluids or other solutions through the catheter. A tip protector is incorporated to block the needle tip and prevent the same from accidental needle stick. A wiper is optionally included to wipe blood deposits on the needle when the same is retracted from the catheter.
US08597248B2	Tissue transfer systems Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented.
US08597242B2	Apparatus and method for establishing the penetration depth of a sliding part of a medical handpiece A device for establishing the penetration depth of a tubular or rod-shaped sliding part in a receiving part and to a medical handpiece using such devices. There is an adjusting element that surrounds the sliding part and which can be adjusted in the longitudinal direction of the sliding part and can be blocked in the particular position by a clamping device to establish the penetration depth of the sliding part in the receiving part. The clamping device is formed by a rocker element that is arranged between the adjusting element and the sliding part. The rocker element can be moved between a first rotational position, which allows the adjusting element to be slid in the longitudinal direction of the sliding part, and a second rotational position, which blocks the adjusting element from being slid, by rotating the adjusting element transversely to the longitudinal direction of the sliding part.
US08597237B2	Universal needlefree bag access device An attachment arrangement has a housing and a needle located within the housing. The arrangement allows administration ports of different sizes to be inserted into and secured within the housing. In certain embodiments, compliant retainers secure the administration port within the housing. In certain other embodiments, the administration port is secured within the housing when the housing is compressed against the administration port by a housing compression element. Once the administration port is secured within the housing, a fluid-tight seal is formed between the attachment device and the administration port.
US08597234B2	Breast shield with sensor A presently preferred embodiment of the invention includes a breast shield for use on a human breast including a breast-receiving portion, which is sized and shaped to receive a nipple and at least some surrounding breast. One or more sensors are connected to the breast-receiving portion and capable of sensing changes in the breast. Alternate embodiments of this aspect of the present invention include a sensor being one or more, for example, of an optical sensor, an electrode, a thermal sensor and an acoustic sensor. The optical sensor may be adapted to detect changes in light reflected from the breast. The electrode may be a pair of electrode parts, a first of which is used to apply an output voltage to the breast and a second of which is used to receive current conducted from the first of the pair of electrode parts. The acoustic sensor may be adapted to detect changes in breast tissue.
US08597232B2	Medical apparatus and single use kit including linear flow control device for use therewith for reconstitution and administration of liquid drug dosage Medical apparatus (10) for use with single use kits (100) containing a flow control device (101), a syringe (40), and one or more vials (60A, 608, 60C), for reconstituting a liquid drug dosage and administrating same. The flow control devices (101) include a core member (116) having an inlet port (107) and a flow control member (117) rotatably mounted on the core member (116) and having at least one vial port (112,113,114) for attachment of a vial and an outlet port (109). Flow control devices (101) are designed to ensure an inlet port (107) is in flow communication with a single port (112,113,114) at each flow control position of at least two predetermined flow control positions of a flow control member (117) relative to a core member (116). The medical apparatus (10) includes a housing (11) having a syringe support (12) for horizontally supporting a syringe (40) and a flow control device support (13) for horizontally supporting a flow control device (101). The medical apparatus (10) can be designed for either manual operation or automatic operation.
US08597231B2	Peritoneal dialysis system having heater pan and weight sensor A peritoneal dialysis machine includes: (i) a housing; (ii) an actuator carried by the housing so as to be able to interact with a peritoneal dialysis fluid carrying disposable; (iii) at least one heating element carried by the housing; (iv) a heater pan providing an upper surface of the housing, the heater pan cooperating with the at least one heater element to provide heat to a container of peritoneal dialysis fluid placed onto the heater pan, the container being part of or in communication with the peritoneal dialysis fluid carrying disposable; and (iv) a weight sensor cooperating with the heater pan to sense the weight of the peritoneal dialysis fluid located within the container.
US08597228B2	Fluid deficit monitoring in a fluid management system Surgical fluid management systems and methods of operating surgical fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.
US08597219B2	Fracture brace The invention provides, in various embodiments, braces that are capable of stabilizing an injured limb, particularly an injured wrist. An exemplary brace fits across the injury in contact with the user's limb and has an adjustable casing and compressible material.
US08597218B2	Musculoskeletal support system A removable air bladder, juxtaposed between support materials, expands or contracts within special voids of orthosis devices. An orthosis system comprise one or more removable air bladders placed on one support material or juxtaposed between two support materials, each of the air bladders being disposed to inflate and deflate by storing and releasing a gas through an airline having a release valve. A pump may be operatively connected to the air line for pumping gas into the air bladder. A pressure sensor may be disposed adjacent to the air bladder to measure pressure of the air bladder against one of the support materials to determine when the pump should be powered on or off. At least one expansion limiter straps may be disposed to control a maximum distance the support materials can be moved apart when the air bladder is inflated.
US08597217B2	Reinforced therapeutic wrap and method A therapy wrap for treatment of at least a portion of an animate body having improved kink resistance. The therapy wrap may be selectively reinforced for improved kink resistance in only a portion of the wrap. The reinforcement may decrease the kink radius. The wrap may include a kink reducer in all or only a selected kink-prone region. The kink reducer may be selectively configured attachment points or spot welds. The therapy wrap may include a reinforcement layer of one or more discrete reinforcement members. The wrap may be formed by pre-tensioning the material layers while forming the fluid bladder and/or gas pressure bladder. The therapy wrap may be adapted to compensate for conditions that normally cause kinking of the wrap or buckling of the fluidic channels. Also disclosed are methods of manufacturing the wrap and methods of administering a temperature-controlled treatment to an anatomical body part.
US08597214B2	Apparatus and method for deep vein thrombosis prophylaxis Apparatus for promoting blood flow in an extremity is disclosed including a gas source and a bladder assembly including a first bladder and a second bladder independently coupled to the gas source. The bladder assembly may be sized to fit within a shoe of a patient and may include a first bladder encircling a second bladder. A controller is operably coupled to the gas source and is configured to control the flow of gas from the gas source to the first and second bladders in order to periodically commence inflation of the first and second bladders in sequence.
US08597213B2	Cervical massaging device Provided is a cervical massaging device that includes: a body that is shaped to contact the side and the rear portion around a cervical spine in a neck; both side pressing members that are disposed and symmetrically spaced apart from each other in the body to contact both sides of the neck and press both sides of the neck by a driving unit; and rotary pressing members that are disposed at a predetermined distance between the side pressing members and rotated by a rotating unit to press the rear portion around the cervical spine in the neck.
US08597212B2	Wrist assisting apparatus A wrist assisting apparatus can smoothly bend and stretch a joint even if a turning shaft of a joint and a rotation shaft of a wearing tool are deviated from each other. Also, an excessive load is not applied to a user. The wrist assisting apparatus of the present invention includes a palm support member for supporting a hand, angle changing members connected to sides of the palm support member, a front arm wearing tool disposed along the front arm, and joint members for forming a rotation shaft of the angle changing member with respect to the front arm wearing tool, wherein the angle changing members are provided on both sides of the palm support member, the joint members are provided on the angle changing members, respectively, and the joint members are located on both sides of a wrist.
US08597208B2	Method and apparatus for measuring analytes A method for measuring the concentration of a compound in the blood of a part of a subject is provided. An invasive or non-invasive sample of blood may used for this determination. Also provided is a device for measuring the concentration of a compound in the blood of a subject.
US08597199B2	Reduced-pain allergy skin test device An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin.
US08597197B2	Monitoring of heart sounds A system comprises an implantable medical device (IMD) including an implantable heart sound sensor circuit configured to produce an electrical heart sound signal representative of a heart sound of a subject and a processor circuit. The processor circuit is coupled to the heart sound sensor circuit and includes a detection circuit, a heart sound feature circuit and a trending circuit. The detection circuit configured to detect a physiologic perturbation and the heart sound feature circuit is configured to identify a heart sound feature in the electrical signal. The processor circuit is configured to trigger the heart sound feature circuit in relation to a detected physiologic perturbation. The trending circuit is configured to trend the heart sound feature in relation to a recurrence of the physiologic perturbation. The processor circuit is configured to declare a change in a physiologic condition of the patient according to the trending.
US08597196B2	Cardiac signal processing apparatus and cardiac signal processing method A cardiac signal processing apparatus includes: a unit for acquiring, from a heartbeat sensor, cardiac signals relating to heartbeats of a subject; a low-pass filter for allowing passage of those cardiac signals having a first predetermined frequency or lower, among the cardiac signals; higher harmonic noise acquisition unit for acquiring harmonic signals of low-frequency noise by performing high frequency extrapolation on the signals output from the low-pass filter; a high-pass filter for allowing passage of those cardiac signals having a second predetermined frequency or higher, among the cardiac signals; and higher harmonic noise removal unit for removing the harmonic signals of low-frequency noise from the signals output from the high-pass filter. It is thus made possible to remove noise from the cardiac signals and to obtain desirable heartbeat detection characteristics.
US08597195B2	Method and apparatus for non-invasively measuring hemodynamic parameters using parametrics An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed.
US08597194B2	System and method for deep vein thrombosis prevention and diagnosis A system and method prevents and diagnoses deep vein thrombosis in a body limb by providing a pressure sleeve having a plurality of individually fillable cells, the pressure sleeve being configurable to be placed around a body limb. A source fills each fillable cell individually, and a pressure sensor measures a pressure in a fillable cell. A controller establishes a fill sequence of each individually fillable cell and a fill time for each individually fillable cell. The controller causes a first individually fillable cell of the pressure sleeve to be filled to a predetermined pressure and causes the pressure of first individually fillable cell of the pressure sleeve to be measured while a second individually fillable cell of the pressure sleeve is filled. The controller determines a presence of deep vein thrombosis in a body limb having the pressure sleeve therearound based upon a measured pressure change in the first individually fillable cell of the pressure sleeve. The monitored pressure changes reflects the effect of venous obstruction on naturally occurred venous flow fluctuations like those caused by the respiratory cycle, and/or artificially created fluctuations like those caused by inflation of a second pressure cell. Relevant data can be collected during routine system application for deep vein thrombosis prevention on a 24/7 basis. In the case deep vein thrombosis is suspected, a controlled and more sophisticated study can be triggered using the same system.
US08597191B2	Ultrasonic imaging apparatus and a method of generating ultrasonic images A processor generates a first Doppler spectrum image representing the velocity of a moving body at each observation point by analyzing the frequency of signals received at the plurality of observation points acquired via Doppler scanning. An interpolator acquires a second Doppler spectrum image consecutively at each observation point time when the ultrasound has not been transmitted to and received from each observation point by the Doppler scanner transmitting and receiving the ultrasound toward and from the plurality of observation points at a plurality of respective times, based on interpolation of the first Doppler spectrum image at each observation point. The interpolator generates a third Doppler spectrum at each observation point by combining the first Doppler spectrum at each observation point and the second Doppler spectrum image at each observation point per observation point.
US08597189B2	Analyte monitoring device and methods of use An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
US08597188B2	Health management devices and methods Methods and devices and systems including a data collection module for receiving and storing analyte data over a predetermined time period from a subject, a user interface unit coupled to the data collection module for providing one or more indication related to the analyte data, a control unit coupled to the data collection module and the user interface unit to control, at least in part the operation of the data collection module and the user interface unit, a communication module coupled to the control unit for communicating one or more signals associated with the analyte data to a remote location, where the user interface unit is configured to operate in a prospective analysis mode including substantially real time output of the analyte level received by the data collection module, and a retrospective analysis mode including limited output of information to the subject during the predetermined time period, and further where the communication module is configured to communicate with the remote location after the analyte data is received and stored in the data collection module over the predetermined time period, are provided.
US08597181B1	Transparent surgical pelvic retractor A transparent surgical pelvic retractor includes a transparent, generally semicircular retractor body having a retractor interior; a concave inner surface facing the retractor interior; and a convex outer surface opposite the inner surface. A surgical retractor method is also disclosed.
US08597178B2	Active drive type medical apparatus and drive control method An active drive type medical apparatus includes: an active mechanism having a rotatable joint provided near the distal end of a long member; an active mechanism driving section; a position/attitude detecting section configured to detect a position/attitude of the active mechanism; an instruction input section for performing instruction input of the position/attitude of the active mechanism; and a force calculating section configured to calculate, on the basis of the instruction input of the position/attitude, a force corresponding to a net external force acting on the active mechanism, by subtracting an estimated driving force estimated in the case where the active mechanism in a no-load state is driven, from a driving force required in the case where the active mechanism is actually driven by the active mechanism driving section from the position/attitude before the instruction input to the instructed and inputted position/attitude.
US08597171B2	Guide glasses A sound and light machine (SLM) produces sound and light that pulses at brain wave frequencies. The SLM is programmed to induce a particular state of consciousness in a user. The SLM includes a left and a right light emitting diode (LED) (3). The LEDs (3) are configured to be placed in front of the user's left and right eyes, respectively, and are programmed to pulse light at a frequency that helps induce the particular state of consciousness in the user. The SLM has a left and a right headphone speaker (4). The speakers (4) are configured to play different tones into right and left ears to produce binaural beats that match the LED pulse frequencies. The SLM also has a microcontroller (5) on circuit board that runs firmware to control the LEDs and headphone speakers.
US08597170B2	Catheter pump A heart pump and a catheter assembly therefor are provided that include a flexible catheter body having a proximal end and a distal end, the catheter body having a plurality of lumens therethrough. The catheter body can be sufficiently flexible to extend from a peripheral access to a patient's heart. The catheter assembly can also include an impeller assembly having an impeller and a housing. The impeller assembly can be coupled with the flexible catheter body such that a tensile force applied to opposite ends of the catheter assembly enhances the security of the connection between the catheter body and the impeller assembly.
US08597169B2	Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye Methods and devices for minimally-invasive delivery of radiation to the posterior portion of the eye including a cannula comprising a distal portion connected to a proximal portion and a means for advancing a radionuclide brachytherapy source (RBS) toward the tip of the distal portion; a method of introducing radiation to the human eye comprising inserting a cannula between the Tenon's capsule and the sclera of the human eye and emitting the radiation from the cannula on an outer surface of said sclera.
US08597163B2	Gyration type exercising device that can exercise a user's body completely A gyration type exercising device includes a gyration unit (10), a damper (20) and a drive handle (30). The gyration unit includes a mounting frame (11) and a rotation wheel (12) rotatably mounted on the mounting frame and driven by the drive handle. The rotation wheel is provided with a rotation shaft (121). The drive handle has a first end pivotally connected with the rotation wheel and a second end provided with a holding bar (31). Thus, when the user's two hands hold the holding bar to move the drive handle in a gyration manner, the user's body has to move forward and backward and has to exert a force on the drive handle successively to rotate the rotation wheel reciprocally so as to exercise the user's body completely.
US08597162B2	Apparatus to facilitate upright posture A mobility apparatus for a patient permitting improved mobility is disclosed. The apparatus includes a frame assembly, a locomotion assembly, a forearm support assembly, a kinematic and kinetic feedback assembly and optionally a back support assembly, where the apparatus provides mobility assistance, while permitting visualization of movement velocity, loaded and unloaded motion, and other information concerning a patients proper use of the mobility assistance apparatus.
US08597159B2	Methods and systems for assisted direct start control Methods and systems are provided for controlling a vehicle system including a selectively shut-down engine, a torque converter and a torque converter lock-up clutch. One example method comprises, during an idle-stop engine shut-down, restricting flow of transmission fluid out of the torque converter, and adjusting engagement of the torque converter lock-up clutch to adjust a drag torque on the engine to stop the engine.
US08597158B2	Method and apparatus for simultaneous parallel control of a torque phase and an inertia phase for hybrid powertrains A method to execute a shift in a powertrain including a plurality of torque generative devices rotatably connected through a first clutch includes operating the powertrain in a continuously variable operating range state, and monitoring a command to execute the shift including monitoring a target speed for a first torque generative device, and monitoring a command to disengage the first clutch. The first clutch is shifted from an engaged state to a disengaged state, including operating a torque phase of the first clutch wherein the first clutch is transitioned from the engaged state to the disengaged state, and simultaneous with the torque phase, operating an inertia speed phase of the first clutch wherein a speed of the first torque generative device is transitioned from an initial speed to the target speed.
US08597156B2	One-way clutch A one-way clutch of an inscribed gear type has a cylindrical outer member having an inner gear at an inner circumference thereof; an inner member rotatably disposed in an inside space of the inner gear, and having gear receivers and a lock edge on one side in a circumferential direction of the gear receiver; and a planetary gear received rollably in each of the gear receivers to mesh with the inner gear. Shafts are projecting from both ends of the planetary gear, and bearing recesses are formed on the gear receiver to receive the shaft. By the engagement between the shafts and the bearing recesses, the planetary gear allows a circumferential displacement within a predetermined range with respect to the inner member required for engaging to or disengaging from the lock edge, and the planetary gear is prohibited from being displaced inward in a radial direction of the inner member.
US08597154B2	Gearing Epicyclical gearing comprising a first and a second gear wheel turning around respective mutually parallel axes, each one comprising a respective first and a respective second crown wheel that are adjacent to each other; the gearing also comprising at least one third and at least one fourth gear wheel that are separate and mutually independent, a support body for the third and fourth gear wheels, the support body having hinge pins formed therewith as a one piece structure, the hinge pins providing a mount for the third and fourth gear wheels on the support body in a rotational manner around a third and, respectively, a fourth hinge axis parallel to the axes, the third gear wheel meshing with the respective first crown wheels and the respective fourth gear wheel meshing with the respective second crown wheels.
US08597148B2	Bearing arrangement for a shift A bearing arrangement for a shaft, particularly a driveshaft (1) in a transmission housing (5) of an automatic transmission with an actuating piston (6) of a shifting element arranged inside the shaft. At least one self-sealing bearing is provided at least on the side of the transmission housing (5) remote from the motor to support the shaft.
US08597143B2	Batting tee and training system An improved baseball or softball batter training system and batting tee is provided. The tee provides a significantly increased useful life as compared to prior art tees as well as improved hitting dynamics. The batting tee forms part of a batter training system which allows multiple batting tees and adapters to be used together to teach proper batting skills to a batter while providing immediate tactile feedback to ensure proper technique.
US08597138B2	Method for surface treating a golf club head A method for surface treating a golf club head, includes: (a) forming a depression unit in the golf club head, the depression unit being indented inwardly from an outer surface of the golf club head, the outer surface being divided into a working area and a non-working area, the depression unit being formed in the working area; (b) filling the depression unit with a shielding material and covering the non-working area with a covering material; and (c) sandblasting the golf club head after step (b) and removing subsequently the shielding material from the depression unit and the covering material from the non-working area so as to form the working area into sandblasted and non-sandblasted regions that differ in gloss intensity.
US08597134B2	Golf club A golf club having a value of L not less than 45.5 inches, with L representing a club length measured with a 60-degree method, includes a shaft, a grip attached to one end of the shaft, and a head attached to the other end of the shaft. A value of r/L is equal to or not smaller than 0.658 and equal to or not greater than 0.732, where r represents a distance from an upper end of the grip to the center of gravity of the golf club. Thus, a long-length golf club achieving an increased head speed can be obtained.
US08597132B2	Play system accessory with sound modules An accessory for a play system includes an elongated surface and a plurality of sound modules coupled with the elongated surface. The elongated surface may be a slide, climbing wall, ladder or any other surface across which a child may slide, crawl, or climb. The sound modules are spaced along a length of the elongated surface and are each configured to emit a unique sound when operated by the child while traversing the elongated surface.
US08597131B2	Driveshaft insert and driveshaft mechanism A driveshaft mechanism tiding a driveshaft insert and a driveshaft are provided. The driveshaft insert is coupled to the driveshaft. The driveshaft insert is configured to couple with a component such that the driveshaft and the component rotate together.
US08597129B2	Device for a drive connection A device for drivingly connecting a drive component and a driven component by a spline includes an inner tooth pattern disposed on one of the components and a mating outer tooth pattern disposed on the other component, wherein one of the components is constructed in two parts and comprises two tooth sections configured for rotation relative to one another, at least one preload spring for tensioning the two tooth sections with respect to each other in the circumferential direction, and means which for assembling the plug-in connection maintain the two tooth sections in mutual alignment, wherein the means are constructed such that the at least one preload spring becomes automatically effective when the drive component and the driven component are connected with an axial assembly motion.
US08597123B2	Method for displaying chat window applied to network game Players input their messages in their video game apparatuses and the messages are once collected at a server apparatus, thereafter they are distributed to all video game apparatuses from the game server apparatus. In a display screen of each video game apparatus, a chat window is displayed in order to display messages exchanged between the players on a game screen including a field and characters of the game. The chat window is sequentially enlarged up to a preset maximum number of lines when a new message is received from the game server apparatus. The chat window is sequentially reduced to the preset minimum number of lines when a predetermined time passes without any reception of new message or when the player performs a specific operation.
US08597120B2	Game device and storing medium that stores game program A game apparatus includes a CPU, and in this game apparatus, a proceeding direction of a player object in a switched scene is detected when the scene is switched. Regarding the proceeding direction, in a case of a drainpipe, and etc., having an exit in the switched scene with a directionality, its direction of the exit is detected, and in a case of a door, and etc., having the exit without directionality, the proceeding direction of the player object in the scene yet to be switched is detected, for example. Furthermore, a screen display position of a display screen is adjusted in such a manner that a display area on a proceeding direction side in the switched scene is rendered as large as possible, for example. Therefore, the display screen, on which the proceeding direction in the switched scene is reflected, is generated and displayed.
US08597118B2	Method, apparatus and system for video tuning of a video switching device for a gaming machine A method, device and system are set forth for controlling a video switching device (VSD) configured to display video from multiple video streams at a video display. Where video signals are received which are unrecognized by the VSD a tuner is coupled to the VSD to control the same to extract video primitives adjust the configuration data so that the video stream will be properly displayed at the video display. In another embodiment the tuner may command the VSD to display a diagnostic dashboard for the gaming machine and its components and network connections.
US08597115B2	Systems and methods for portable wagering mediums Some embodiments are associated with wagering game devices and/or portable wagering mediums. Some portable wagering mediums are capable of outputting various indications related to one or more potential or current statuses of the portable wagering mediums. Some wagering game devices are operable to (i) determine a status of a portable wagering medium and (ii) cause, based on the determining, an outputting of an indication of the status via an output device coupled to the portable wagering medium. In some embodiments, a central server or other device conducts the determining of the status and/or the causing of the outputting. The status of a portable wagering medium may be based on one or more of many different factors or metrics.
US08597114B2	Systems and methods for assisting players in arranging hands for table games A system and method for enabling play of a casino table card game. Multiple randomized sets of playing cards of known composition are formed and delivered, and are set by following automatically generated house way instructions. An automatic card shuffler is configured to deliver randomized sets of physical cards, the shuffler equipped with a playing card reading system that reads at least one of a rank and suit of markings on each of the playing cards. A processor receives the read card information from the playing card reading system and determines a composition of each individual set of playing cards dispensed. At least one display is in communication with a processor programmed with house way rules for displaying instructions on how to set hands from a distributed set of cards a house way. Processors of the present invention may also cause a display of a house commission amount.
US08597112B2	External evaluator An external evaluator can evaluate the wagering game outcome data against rules and/or criteria that lead to an exciting and entertaining event separate and/or distinct from the wagering game itself. An external evaluator evaluates game outcome data, received from a wagering gaming machine via a network, against criteria for a plurality of events (203). It is determined that the game outcome data satisfies a criterion of a first of the plurality of events. The criteria comprise the criterion. A device is determined that performs an operation that, at least partially, implements the first of the plurality of events (323). A communication that indicates the first of the plurality of events is transmitted to the device via the network (327).
US08597109B2	System and method for increasing player participation A system and method are provided to combine a gambling establishment player club with one or more second chance games. Players are thereby given multiple opportunities and incentives to interact with the gambling establishment and player club. The gambling establishment is thereby able to gather valuable player data, build player profiles, and incentivize players to take actions desired by the gambling establishment.
US08597108B2	Asynchronous persistent group bonus game An asynchronous persistent group bonus game system, method and apparatus may have a plurality of gaming machines including a first processor and a bonus server having a second processor. The first processor may be configured to: determine when a bonus game session event is triggered, transmit a bonus game session request to the second processor, and receive an end session notification from the second processor. The second processor may be configured to execute and maintain the always-on asynchronous persistent group bonus game, receive a bonus game session request from at least one of the plurality of gaming machines, instantiate a bonus game session inside the continuous asynchronous persistent group bonus game for the at least one gaming machine, determine when an end session trigger has been triggered for the bonus game session, and transmit an end session notification to the at least one gaming machine if it is determined that the end session condition has been triggered.
US08597105B2	Gaming machine A gaming machine is provided, which includes an interface portion, a controller, a memory, a first power supply, and a second power supply. The interface portion is connected with at least one unit used for executing a game. The controller controls the unit connected to the interface portion and detects an occurrence of abnormal operation at the unit. The memory stores identification information for identifying the unit, and further stores historical information that includes information related to the occurrence of abnormal operation detected by the controller in connection with the identification information. The first power supply supplies a voltage required for operation of the controller. The second power supply supplies the voltage required for operation of the controller if a voltage supplied for the controller by the first power supply is less than the voltage required for operation of the controller.
US08597094B2	Game machine, controlling method, program and information storage medium of the game machine for improving operability for a user when a player character of an opponent team holds a moving object To provide a game device capable of improving operability for a user when a player character of an opponent team holds a moving object in a sport game to be played by a user team and the opponent team. A first marker control unit (72d) controls the position of a marker player character selected from among the player characters of the user team, based on the position of a marking target player character selected from among the player characters of the opponent team and a predetermined position. A second marker control unit (72e) controls the position of the marker player character, based on the position of the marking target player character and the position of a moving object or the position of a player character holding the moving object. The marker control switching unit (72g) switches between the first marker control unit (72d) and the second marker control unit (72e), based on a result of determination as to whether or not a predetermined switching condition is satisfied.
US08597093B2	Methods and systems for encouraging athletic activity Individuals may be encouraged to perform athletic activity based on punishments or adverse effects that may be applied if the individual loses an athletic activity competition. For example, a user's device may be adversely affected by visual or functional effects configured to obscure or obstruct one or more functions of the user's device. The punishment or adverse effect might not be removed or deactivated until a user has completed a new competition without losing. In some arrangements, the user may be required to win in order to have the adverse effect removed.
US08597090B2	Coin counter and distributor A coin apparatus (100) includes a central housing (102) with a coin holding interior (104). An upper funnel/distributor section (114) facilitates removal of excess coins when said interior is being filled with a predetermined number of coins. The coin apparatus (100) also includes coinage selectors (121), each having an allocation slot (122). Extending inwardly towards the center of the allocation slot (122) is a resilient arm (124) having a button (126) at the end thereof. Each button (126) has an inner edge (127) which is capable of securely abutting edges (128) of one or more of the coins (126) when forces are exerted by the user.
US08597083B2	Blade sharpening system for multiple blade shapes A blade sharpening system using the interior surface of a grinding wheel against which a blade is drawn along its entire length for sharpening. The sharpening system includes a blade holding configuration having multiple hinged arms. A cam operating between two of the hinged arms serves to alter the angle of incidence between the blade and the grinding wheel as the blade is drawn across the grinding wheel. The result is that a wide variety of different blade configurations can be easily accommodated by the sharpening system.
US08597081B2	Chemical mechanical polishing apparatus having pad conditioning disk and pre-conditioner unit A pad conditioning disk, a pre-conditioning unit, and a CMP apparatus having the same are provided. The pad conditioning disk includes a base in which mountain-type tips and valley-type grooves are repeatedly connected to each other, and a cutting layer formed on the base layer. The cutting layer including conditioning particles deposited on surfaces of the tips and grooves. A surfaces roughness of conditioning particles deposited on the surfaces of the tips is less than a surface roughness of conditioning particles deposited on the surfaces of the grooves.
US08597076B2	Flexible enclosures for maintenance operations A containment assembly is described that includes a flexible enclosure and a panel attached to the flexible enclosure. The flexible enclosure includes a first opening that defines a periphery that is operable for attachment around a work area. The panel is attached to the enclosure about a periphery defined by a second opening in the enclosure. A sealable access port is also associated with the enclosure, operable to provide a user with access to an interior of the enclosure.
US08597071B2	Brasserie with scented member and dispenser therefore A fragrant brasserie according to one embodiment includes a body portion having a pair of cups, a pair of side straps that engage one another for securely attaching the brasserie to a person's body, and a pair of shoulder straps connected between the cups and the side straps. The body portion has a front section located between the pair of cups that includes an opening leading into an interior compartment. The brasserie also includes a fragrant article that is removably disposed within the interior compartment. The fragrant article has a fragrance associated therewith that provides a pleasant scent that can be experienced over a period of time. The fragrant article is formed of a material that absorbs a liquid and includes a liquid fragrance that impregnates the material so as to provide a pleasant smelling experience when the fragrant article is worn with the brasserie.
US08597069B2	Toy race track system A toy car race track set comprised of a plurality of easily connectible track sections, in which the track sections have novel provisions for integrating the track sections with structures formed with K'NEX rod and connector elements, including but not limited to structures for elevating track sections above a support or above other track sections, providing obstructions on the race course, and the like. A variety of shapes and forms of track sections enables a substantially limitless variety of track configurations to be assembled. Each section is provided at each end with at least one tongue element and one slot element positioned such that the tongue element of one section is received in the slot of an adjacent section with a desired, snap-in action substantially preventing unintended separation. Optional locking pins are provided for positively locking the track sections to other sections when desired.
US08597066B2	Lightweight outboard electric motor system An outboard electric motor kit that includes an electric motor assembly with a unitized propeller hub, a transom mount, a rechargeable electric battery, and an optional recharger. The assembly includes an electric motor unit located in an upper housing. A lower tube stem is attached and that extends downward from the upper housing to a lower housing. Formed on the lower housing is a receiving cavity with a rearward facing propeller hub opening. A drive shaft coupled to the motor unit extends downward inside the lower tube stem and mounted to a gear support block located in the receiving cavity. Mounted on the end of the drive shaft is a main gear. Mounted on the gear support block is a fixed axle that extends coaxially aligned through the propeller hub opening. Extended through the opening and coaxially mounted over the fixed axle is a removable propeller hub assembly.
US08597063B2	Modular electrical assembly with jumper storage A modular electrical assembly adapted to be electrically connected to at least one other modular assembly by means of a connecting jumper. The assembly includes a storage structure for storing the connecting jumper associated with the assembly. A method of electrically connecting a modular electrical assembly to at least one other modular electrical assembly is also disclosed.
US08597062B2	Electrical contact The electrical contact includes a wire crimping portion receiving an electrical wire, a cylindrical power contact portion for connection with a complementary contact. The power contact portion comprises includes a body mechanically retained on the wire crimping portion and spring legs depending from the body and to be contacted with the complementary contact. The electrical contact further includes an electrically insulating cover covering the spring legs. The cover additionally includes fool proof features to prevent incorrect assembly of the cover into passages of the housing.
US08597061B2	Earphone plug with switch device An earphone plug applicable to different system specifications includes a terminal and a switch device. The earphone plug is inserted into an earphone jack of an external electronic device for transmitting signals by a plurality of exposed signal interfaces of the terminal. The switch device combined with the terminal has a first conductor and a second conductor. When the switch device is switched between a first mode and a second mode, the first conductor and the second conductor alternately contact with two of the signal interfaces. Thus, the signal transmission defined by the signal interfaces is changed and the earphone plug is applicable to electronic devices with different system specifications.
US08597058B2	Card holder A card holder adapted for converting a micro SIM card into a standard SIM card in size and shape includes an insulating housing of a flat board shape which is in accordance with the standard SIM card in size and shape, and defines a card groove in accordance with the micro SIM card in size and shape and in accordance with the standard SIM card in contact position for receiving the micro SIM card in place. At least one groove sidewall of the card groove defines an open slot spaced from the card groove for accordingly forming at least one elastic arm between the open slot and the card groove, wherein the elastic arm further projects into the card groove for resisting against the micro SIM card. A metal part is molded in the insulating housing and exposed in the card groove for supporting the micro SIM card thereon.
US08597056B2	Card edge connector A card edge connector is provided for mounting to a printed circuit board (PCB). The card edge connector includes a housing having a mating side, a mounting side, and a card slot that extends into the mating side. The card edge connector also includes first and second contacts held by the housing. The first and second contacts include mounting segments that extend outwardly from the mounting side of the housing. The mounting segments include mounting interfaces. The mounting segments of the first and second contacts are configured to be electrically connected to corresponding contact pads on the PCB at the mounting interfaces. The mounting interface of the first contact is offset from the mounting interface of the second contact in a direction generally away from mounting side of the housing.
US08597054B2	CAN bus automatic line termination A network interface includes a receptacle configured to receive a plug, a first contact and a second contact each disposed in the receptacle, and a combination of a resistive element and a normally closed switch arranged in series with each other. The combination is coupled between the first contact and the second contact, and has a first configuration in which the switch is opened responsive to a presence of the plug within the receptacle, and a second configuration in which the switch is closed responsive to an absence of the plug from the receptacle.
US08597048B2	Multilevel connector system The invention relates to a connector system comprising a first connector having a plurality of first contact terminals (E, F, G, J); a second connector having a plurality of second contact terminals, wherein the second contact terminals (A, B, C, D) and the electrical device are arranged such that, while connecting, the first contact terminals come into contact with a first subset of the plurality of second contact terminals in a first connecting stage and while the connecting further proceeds the first contact terminals come into contact with a second subset of the second contact terminals, such that in the first connecting stage an electrical quantity between two of the first contact terminals is detectable which is different from the electrical quantity in an uncoupled condition of the connectors, and in the second connecting stage a further electrical quantity between at least two of the first contact terminals is detectable which is different from the electrical quantity detected in the first connecting stage.
US08597044B2	Connector receptacle housings having reduced-wear finger contacts and reduced seam visibility Structures, methods, and apparatus that provide connector receptacles that have a reduced tendency to scratch and otherwise mar connector inserts, have an aesthetically-pleasing appearance, and have an improved tactile response when inserts are inserted. Various examples reduce scratches and wear by utilizing domes, cylinders, balls, or other structures as finger contacts in a connector receptacle. Another example provides aesthetically-pleasing connector receptacle enclosures by forming receptacle enclosures using the same type of material, or material having the same or similar color or texture, as is used for enclosing the electronic device that includes the receptacle. Another example provides an aesthetically-pleasing receptacle enclosure by forming receptacle enclosures that are, in part or in whole, contiguous or formed with the housing.
US08597039B2	Vehicle-side connector with water drainage paths extending from an outwardly open recess A vehicle-side connector (10) to be connected to a charging connector in charging a battery of a vehicle includes a receptacle (33) which is connectable to the charging connector, a mounting portion (31) which is provided to partition between the receptacle (33) and a vehicle (B) and to be fixed to the vehicle, a recess (40) which is open upward and provided on the top of the connecting portion (33), and water drainage paths (41) formed in inner surfaces of the recess (40) without penetrating through the mounting portion (31).
US08597038B2	Connector A connector is connectable to a card. The connector comprises an eject member including a pressed portion. The eject member is configured to eject the card along an eject direction when the pressed portion is pressed by an operation member separated from the connector and having a tip. The pressed portion is formed by bending a metal plate so as to have a receiving wall and a side wall. The receiving wall is configured to be brought into abutment with the tip of the operation member so that the pressed portion is pressed by the operation member. The side wall extends in a direction crossing the receiving wall so that the side wall is located lateral to the tip upon the abutment of the tip with the receiving wall.
US08597033B2	Receptacle connector A receptacle connector includes an insulating housing with a plurality of openings apart opened in a front face thereof. A terminal group includes a ground terminal embedded in the insulating housing. The terminal group has a plurality of contact slices molded in the insulating housing and exposed through the openings respectively, and a plurality of touching arms elastically stretching outside the insulating housing. At least one connecting member is molded in the insulating housing to electrically connect with the ground terminal, and has a connecting slice exposed outside and abreast with the front face of the insulating housing. A metal shell is mounted to the front face of the insulating housing and point welded with the connecting slice. A window is opened in the metal shell and located to face the openings for further exposing the contact slices therethrough. A waterproof washer is sealed around the metal shell.
US08597031B2	Systems and methods for computerized interactive skill training The present invention is directed to interactive training, and in particular, to methods and systems for computerized interactive skill training. An example embodiment provides a method and system for providing skill training using a computerized system. The computerized system receives a selection of a first training subject. Several related training components can be invoked, such as reading, watching, performing, and/or reviewing components. In addition, a scored challenge session is provided, wherein a training challenge is provided to a user via a terminal, optionally in video form.
US08597029B2	Pulse simulation unit This invention relates to pulse simulation units for use in patient simulators, where the device comprises a base body, an upper actuator body located in parallel above the base body, one leaver body at each longitudinal end of the base body, which in their lower portion is pivotally attached to the base body and in their upper portion is pivotally attached to the actuator body, and at least one shape memory alloy wire attached in one end to the lower portion of each leaver body below the pivotally attachment to the base body and in the other end to the base body, and where the length of the shape memory alloy actuator wire is adjusted such that when no electric pulse is delivered, the length of the wire(s) allow the leaver bodies to be more or less folded in towards the base body and hold the actuator body to form a compressed position at a first distance above the base body, and such that when the actuator wire(s) contract due to exposure to an electric pulse they will rotate the lever bodies some degrees and thus cause the actuator body to be lifted to an expanded position at a second distance>the first distance above the base body.
US08597024B2	Two-part dental implant A two-part dental implant includes distal and proximal stem portions which in an interconnected condition at least indirectly adjoin each other at a connecting location and have mutually facing surfaces in the region of the connecting location. A sealing body is provided between the mutually facing surfaces of the distal and proximal stem portions. The sealing body has sealing surfaces which face towards the mutually facing surfaces and which in the interconnected condition of the two stem portions bear sealingly against the mutually facing surfaces thereof. In addition, mutually facing abutment surfaces are provided between the distal and proximal stem portions. These mutually facing abutment surfaces bear against each other in the final assembled dental implant and limit the degree of approach of the two mutually facing surfaces of the stem portions between which the sealing body is arranged.
US08597023B2	Dental implant and method for providing a mounting part Disclosed herein is a dental implant with a post part which can be introduced into a jaw bone and with a mounting part on which a dental prosthesis piece can be mounted. The dental implant allows a dental technician to choose a particularly favorable orientation for further assembling of the components, and at the same time to make it possible for the person performing the treatment to make use of the advantages of an indexing without using auxiliary tools.
US08597018B2	Weldless injection mold apparatus A weldless-type injection mold apparatus is provided. The weldless-type injection mold apparatus includes an upper mold, a lower mold engaged to the upper mold to form a cavity for injection-molding of products, a heating unit formed on one side of the cavity of at least one of the lower and upper molds to heat a resin injected into the cavity, a first cooling unit formed at the at least one of the lower and upper molds to prevent the injection mold from being over-heated, and a second cooling unit installed between the heating unit to cool an area surrounding the cavity and an injection-molded product.
US08597016B2	System for producing pultruded components A system for producing a pultruded component includes a fixture for providing fibrous reinforcements, a system for providing a polymeric resin, and an impregnation die for coating the fibrous reinforcements with the polymeric resin precursor. The impregnation die includes a first chamber and a second chamber. The fibrous reinforcements include fiber tows made of a plurality of fibers. The system also includes a curing die for forming the pultruded component. The first chamber of the impregnation die is configured for coating exterior surfaces of the fiber tows with the polymeric resin precursor. The second chamber of the impregnation die is configured for coating the plurality of fibers within the fiber tows with the polymeric resin precursor.
US08597014B2	Actuator An actuator is disclosed that includes a body, the body having a face, and a plurality of conduits located in the body, each conduit deformable in response to a change of pressure within the conduit, the deformation of the conduit configured to cause a deformation of the face.
US08597013B2	Tensioning rail for a membrane of a membrane press The invention describes a tensioning rail (3) for a membrane (2) of a membrane press. To allow a simpler and more rapid assembly and disassembly of the membrane (2) than in known devices, the tensioning rail includes a support rail (8), in which at least one tensioning strip (13) is mounted detachably, whereby the tensioning strip (13) is designed for securely clamping onto the edge of the membrane (2). In this way it is possible to equip a new replacement membrane (2) with tensioning strips (13) independently and outside of the membrane press, which then only need to be attached to the support rail (8). In this case the support rail does not need to be disassembled, but remains on the membrane press the whole time. A further essential advantage is that the tensioning rail (3) can also be installed into existing membrane presses, for example as a replacement for an existing securing device for the membrane.
US08597011B2	Apparatus and method for exposing a substrate to UV radiation using a reflector having both elliptical and parabolic reflective sections Embodiments of the invention relate generally to an ultraviolet (UV) cure chamber for curing a dielectric material disposed on a substrate and to methods of curing dielectric materials using UV radiation. A substrate processing tool according to one embodiment comprises a body defining a substrate processing region; a substrate support adapted to support a substrate within the substrate processing region; an ultraviolet radiation lamp spaced apart from the substrate support, the lamp configured to transmit ultraviolet radiation to a substrate positioned on the substrate support; and a motor operatively coupled to rotate at least one of the ultraviolet radiation lamp or substrate support at least 180 degrees relative to each other. The substrate processing tool may further comprise one or more reflectors adapted to generate a flood pattern of ultraviolet radiation over the substrate that has complementary high and low intensity areas which combine to generate a substantially uniform irradiance pattern if rotated. Other embodiments are also disclosed.
US08597008B1	Method and apparatus for controlling the sidewall vs. tread curing temperature in a tire mold The present invention relates to an apparatus for providing the upper and lower portions of two-part tire molds with an expansible opening to provide clearance for the insertion of green tires, in particular large green tires of the sort used on industrial or off-road vehicles. The tire mold according to the present invention provides a segmented tire mold wherein a plurality of circumferentially arranged segments which contribute to the shaping of the circumferential tread portion of a tire. The sidewall rings and the tread segments may include internal cavities which house insulating material.
US08597007B2	Screw pump rotor and method of reducing slip flow A pump rotor for a screw pump includes a shaft, a first set of threads disposed on a portion of an outer surface of the shaft, at least one thread of the first set of threads including a groove disposed on an end portion thereof, and a ring seal disposed on the groove such that the ring seal is configured to protrude outwardly from the groove and to rest against an inner surface of a liner of the screw pump, and the groove is sized so as to allow the ring seal to move radially with respect to the plurality of threads as the rotor is deflected.
US08597004B2	Scroll type compressor having an intercommunication path in which a pin member is inserted A scroll type compressor including a fixed scroll, a movable scroll engaged with the fixed scroll and a hermetically sealed container, one of the fixed scroll and the movable scroll including an intercommunication path having a lower hole opened to the outside of the one scroll and an insertion hole formed by subjecting the lower hole to reaming processing from the one end to a position of a predetermined depth of the lower hole, a pin member that is slightly smaller in diameter than the intercommunication path and movably inserted in the intercommunication path, and a screw member that is provided at one end of the intercommunication path to close the one end of the intercommunication path so as to press the pin member against the end of the back side of the intercommunication path.
US08597003B2	Direct control variable displacement vane pump A lubrication system for a power transmission device includes a variable displacement vane pump including a moveable control ring for varying the displacement of the pump. A linear actuator directly acts on the control ring for moving the control ring between maximum and minimum pump displacement positions. The linear actuator includes an electric motor for rotating a drive member. The drive member engages a driven actuator shaft to cause linear translation of the actuator shaft in response to rotation of the drive member. A control system includes a controller for signaling the actuator to extend or retract the actuator shaft to vary the pump displacement.
US08596998B2	Piezoelectric micro-blower A piezoelectric micro-blower includes an inner case to which a peripheral portion of a vibrating plate including a piezoelectric element is fixed such that a blower chamber is defined between the inner case and the vibrating plate and an outer case arranged to cover an outer periphery of the inner case with a gap therebetween. The inner case is elastically retained in the outer case by a plurality of connecting portions. A first opening is provided in a top plate portion of the inner case that faces a central portion of the vibrating plate, and a second opening is provided in a top plate portion of the outer case that faces the first opening. A central space is provided between the top plate portions, and fluid introduced from the outside is guided to the central space through the gap between the inner and outer cases. The vibrating plate is driven in a bending mode so that air is sucked into the central space and is discharged through the second opening. The connecting portions prevent leakage of vibration of the vibrating plate from the inner case to the outer case, thereby reducing energy loss.
US08596995B2	Sealing structure and compressor A sealing is arranged between a rear head having an ejection port configured and arranged to eject compressed refrigerant and a rear muffler disposed so that a muffler space is formed between the rear muffler and the rear head. The rear head includes a main body having a bearing hole, an annular boss portion protruding from the main body and circumscribing the bearing hole, and an annular side wall protruding from the main body and circumscribing the boss portion. The rear muffler has an opening and is fastened to the end surface of the side wall so that the peripheral portion of the opening contacts the end surface of the boss portion. Preferably, the end surface of the boss portion has a part entirely further from the main body than the end surface of the side wall.
US08596993B2	Dual-pump supply system with bypass-controlled flow regulator A dual-supply fluid distribution system includes a first pump having an inlet and an outlet. The first pump is configured to supply a first fluid flow. A second pump has an inlet and an outlet, and is configured to supply a second fluid flow. A check valve is coupled between the first and second pump outlets. The check valve is configured to combine the second fluid flow with the first fluid. A bypass valve is coupled to the outlet of the first pump. The bypass valve has an integral pilot valve and is configured to permit fluid flow from the pump outlets in excess of the fluid demand to recirculate back to the first and second pump inlets. The bypass valve and integral pilot valve are configured to cause the check valve to open when the flow of fluid through the bypass valve is below a threshold amount.
US08596991B2	Thermally efficient multiple stage gear pump A multiple stage pump for delivering fuel to an engine is disclosed which includes a pump housing, a boost stage operable at engine start to draw fuel into the pump housing at a boost stage pressure, a first pumping stage operable upon engine start for receiving fuel from the boost stage and delivering the fuel from the pump housing to a fuel metering unit, a second pumping stage operable upon engine start and during engine cruise operation for receiving fuel from the boost stage and delivering the fuel from the pump housing to said fuel metering unit, and a switching valve in fluid communication with the first and second pumping stages, and configured to control fuel flow through the first pumping stage in dependence on changes in boost stage conditions such as pressure or shaft speed.
US08596990B2	Pneumatic vacuum generator A pneumatic vacuum generator includes at least one venturi nozzle having a flow cross section which deviates for a circularity. The venturi nozzle may thus have a substantial rectangular or non-circular flow cross section like for example an oval flow cross section or an elliptical flow cross section. At least two plates are disposed in parallel relationship and joined in sandwich construction, with one of the plates constructed to accommodate the venturi nozzle.
US08596989B2	Dual injection airlift pump The dual injection airlift pump has a hollow tubular body through which the liquid being pumped passes upward from the lower intake end to the upper outlet end. Air or other gas is injected into the liquid in the pump body, the less dense gas adding buoyancy to the liquid and entraining the liquid to rise toward the outlet end. The dual injection airlift pump includes two air injection stages, with the first or lower stage having a perforated interior sleeve allowing the gas to pass therethrough to be injected radially into the liquid. The second, upper stage has an impervious sleeve defining a gap between the sleeve and the interior surface of the pump wall, the lower end being sealed and the upper end open. Air is injected between the sleeve and pump wall, the air exiting at the upper or downstream end in an axially peripheral flow pattern.
US08596986B2	Unflared compressor blade A compressor component having an airfoil with a profile in accordance with Table 1 is disclosed. The compressor component, such as a compressor blade, has an increased thickness over a portion of the airfoil span in order to increase stiffness. Furthermore, the airfoil has been restacked so as to induce a compressive stress in the blade root/attachment area. The increased stiffness and restacked airfoil combine to improve high-cycle fatigue capability of the compressor component.
US08596984B2	Resin fan There is provided a resin fan capable of enhancing the mechanical strength in a weld part in view of the direction of reinforcing fiber. On the outer peripheral surface 16a of a cylindrical rib 16, convex parts 30 are formed in the middle portions between the portions in which radial ribs 18 adjoining each other are connected to the cylindrical rib 16. The cylindrical rib 16 is formed so that the thickness T in the radial direction thereof is decreased gradually from the base part 16c thereof toward the tip end part 16d. Further, the height H1 of the cylindrical rib 16 is set so as to be larger than the height H2 of the radial rib 18. Thereby, at the time of molding, the resin flows in the portions of the cylindrical rib 16 and the convex parts 30 are complicated, and thereby the orientation of glass fiber mixed in the resin is complicated.
US08596981B2	Annulus filler for a gas turbine engine An annulus filler for mounting to a rotor disc of a gas turbine engine is provided to bridge the gap between adjacent blades. A first part is connectable to the rotor disc between adjacent blades. There is a separate second part that engages with the first part after connecting the rotor blades to the rotor disc. When installed, the filler is spaced from each blade by a respective clearance gap (G), and an operational configuration in which it contacts each of said blades. Engagement of the second part with the first part is effective to urge the first part from said installation configuration to said operational configuration and thus into blade contact. The first part may have a mounting region for connection to the rotor disc and allow, in said first step of said procedure, the mounting region to remain visible from a radially outer viewpoint.
US08596979B2	Ceiling sweep fan A ceiling sweep fan comprising a rotor supported for axial rotation about upper and lower housings, the rotor supporting a plurality of radially extending fan blades, the upper housing and rotor enclosing an electric motor that drives the rotor; wherein the fan includes stop means to cause the rotor to stop at a fixed position relative to the upper and lower housings.
US08596966B1	Turbine vane with dirt separator A turbine stator vane with a cooling circuit that improves the cooling effectiveness of the airfoil as well as collects any dirt particles before passing the clean cooling air through the cooling circuit. The airfoil includes a 3-pass aft flowing serpentine circuit with a first leg located along the airfoil leading edge and connected to a showerhead arrangement for film cooling discharge. A cooling air supply channel is located between the first leg and the second leg of the serpentine flow circuit, and the cooling supply channel includes ribs arranged to produce a vortex flow within the cooling air that collects the dirt particles within a center of the vortex flow and deposits the dirt particles at the bottom of the channel. The vortex flow cooling air flows through impingement holes to produce impingement cooling on the backside wall of the leading edge with clean cooling air. The vortex flow pattern produces higher flow velocities at the outer periphery of the vortex which produces a higher impingement jet velocity of the cooling air to improve convection and impingement cooling capability.
US08596964B2	Turbines having a debris release chute In a hydroelectric turbine having a rotor disposed within a housing, the rotor having an annular outer rim received by a channel in the housing, the improvement comprising providing at least one debris release chute in said housing such that debris captured between the rotor and the housing is released through the debris release chute.
US08596952B2	Method and transport device for positioning loading aids prior to the transfer thereof into a shelf The invention relates to a method and a transport device (207) for positioning loading aids (208) prior to the transfer thereof into a shelf compartment (209) on storage spaces (211a to 211d) arranged behind one another using a transport device (207). The loading aids (208) are positioned against one another, behind one another against a first stop device (243 to 247) of the transport device (207) in the transfer direction (210), then a separating device (256, 257) is adjusted in the movement path (251) between the loading aids (208) and the front loading aid (208) in the transfer direction (210) is positioned against the separating device (256, 257) and the rear loading aid (208) in the transfer direction (210) is positioned against a second stop device (243 to 247) of the transport (207) in the transfer direction (210). Afterwards a third stop device (243 to 247) is adjusted between the separated loading aids (208).
US08596947B1	Airport baggage accumulation rack having rotatable shelves, and method for handling baggage A rack for loading and accumulating bags comprises: a) a frame; b) a plurality of similarly sized shelves maintained in a horizontal position; c) said frame carrying similar shelves on an opposite side; d) tracks and a powered mechanism to rotate the shelves. After a first shelf positioned on a bottom portion of the first long side is loaded, it can be moved upwardly, generally concurrently rotating all of the shelves around the rack. All of the shelves can be thereby loaded from the portion position on a first long side. Lifting and carrying required to completely fill the rack is thereby minimized. Most preferably a shelf unloading mechanism is provided to push the shelf and/or bags loaded thereon off the rack; so that all of the shelves can be discharged therewith, by rotatably moving all of the shelves after each shelf has been unloaded.
US08596946B2	Watercraft dry dock storage systems and methods There is provided a storage system for storing and retrieving watercraft or other items to or from a storage position in a storage area as part of an enclosure having a plurality of storage areas. The storage system may include at least one carrier to support the item during movement to or from a storage position, and a positioning system to move the carrier system. An elevator system is usable to move the positioning system and carrier system to and from a storage area, and a control system is usable to control the positioning system to move the carrier system and item into and out of its storage position.
US08596945B2	Device for filling oven chambers of a coke oven An apparatus for charging chambers of a coke oven has a horizontal screw conveyor with a downwardly open outlet and a telescopic charging chute below the outlet having an upper intake funnel and a telescopic lower part alignable with the charging ports by horizontal and longitudinal displacement. A support frame carries the intake funnel and a lifter for vertically displacing the telescopic lower part. A traveling frame in which the support frame moves transversely can also move longitudinally on rails. A seal on a top side of the support frame surrounds the intake funnel of the telescopic charging chute, works together with a horizontal lower flange surface on the outlet of the horizontal screw conveyor, and permits horizontal movement of the intake funnel relative to the outlet of the horizontal screw conveyor.
US08596939B2	Apparatus and method for cutting teeth in workpieces and associated tool set A method for cutting teeth in workpieces, wherein, in a roughing operation, a substantially uncut blank receives rough teeth using a cutting tool having cutting teeth. Operation teeth are produced, the tooth width of which is defined by the spacing between the flanks of the teeth and is greater than the target dimension. In a subsequent deburring operation, a chamfer is incorporated into the end face edge of the tooth flanks, accompanied by the removal of an end face burr. Lastly, in a smoothing operation, the tooth width of the teeth is brought to the target dimension by machining the tooth flanks.
US08596936B2	Apparatus for applying leverage force to a hand drill An apparatus for applying a leverage force to a hand drill has a rigid elongated support having a first end and a second end. A travel member is movable axially along the support with a friction lock for locking the travel member to the support in a selected axial position. A lever is pivotally attached to the travel member. The lever has an engagement surface for engaging a spine of a hand drill, whereby a force is exerted upon the hand drill by means of the lever. A stop is positioned at the second end of the support to prevent axial movement of the support when a force is exerted by the lever.

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