Document Document Title
US08536417B1 Soybean cultivar CL0911580
The present invention is in the field of soybean variety CL0911580 breeding and development. The present invention particularly relates to the soybean variety CL0911580 and its progeny, and methods of making CL0911580.
US08536409B2 COS for mechanical harvest
The present invention relates to a Lactuca sativa L. var. longifolia Lam seed which has a solid main vein and narrow base leaves, dark green outer leaves, short core, absence of fringe burn, and absence of tipburn. A specific embodiment is designated 41-69 RZ, referred to as Actarus. The present invention also relates to a Lactuca sativa L . var. longifolia Lam plant produced by growing the “41-69 RZ” (“Actarus”) seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 41-69 RZ.
US08536396B2 Production of olefins
A process for converting a hydrocarbon feedstock to provide an effluent containing light olefins, the process comprising passing a hydrocarbon feedstock, the feedstock containing at least one C1 to C6 aliphatic hetero compound selected from alcohols, ethers, carbonyl compounds and mixtures thereof and steam in an amount whereby the feedstock contains up to 80 weight % steam, through a reactor containing a crystalline silicate catalyst to produce an effluent including propylene, the crystalline silicate having been subjected to de-alumination by a steaming step and being selected from at least one of an MFI-type crystalline silicate having a silicon/aluminium atomic ratio of from 250 to 500 and an MEL-type crystalline silicate having a silicon/aluminium atomic ratio or from 150 to 800.
US08536395B2 Catalyst with an ion-modified binder
A solid catalyst, such as a molecular sieve catalyst or solid acid catalyst, is supported by a binder, such as amorphous silica or alumina, wherein the binder is charged with metal ions to form an ion-modified binder. The ion-modified binder is capable of attachment to polar contaminants and inhibit their contact with the catalyst. The catalyst can be a zeolite and can be the catalyst for an alkylation reaction, such as the alkylation of benzene with ethylene.
US08536394B2 Process for producing alkylated aromatic compounds and process for producing phenols
According to a process of the invention, a ketone, an aromatic compound and hydrogen as starting materials are reacted together in a single reaction step to produce an alkylaromatic compound in high yield. A process for producing phenols in the invention includes a step of performing the above alkylation process and does not increase the number of steps compared to the conventional cumene process. The process for producing alkylated aromatic compounds includes reacting an aromatic compound such as benzene, a ketone such as acetone and hydrogen in the presence of a solid acid substance, preferably a zeolite, and a silver-containing catalyst.
US08536393B2 Integrated process to produce C4+ hydrocarbons with removal of brominated organic impurities
The present invention provides an integrated process for producing aromatic hydrocarbons and/or C4+ non-aromatic hydrocarbons from low molecular weight alkanes, which includes contacting the low molecular weight alkanes with a halogen and coupling the monohaloalkanes to form aromatic hydrocarbons and/or C4+ non-aromatic hydrocarbons.
US08536392B2 Series catalyst beds
The invention relates to series reactor beds containing different oligomerization catalysts and having independent temperature control, and processes for the oligomerization of light olefins to heavier olefins using such series reactor beds.
US08536390B2 Profitable method for carbon capture and storage
The present invention generally relates to a method for sequestering carbon dioxide. Biomass is converted into paraffinic hydrocarbons. The paraffinic hydrocarbons are steam cracked into olefins. The olefins are polymerized into non-biodegradable polyolefins.
US08536385B2 Process for preparing dimethyl ether and process for preparing a mixture of dimethyl ether and methanol
A process for preparing dimethyl ether or a mixture of dimethyl ether and methanol including passing a raw gas containing carbon monoxide and hydrogen through a catalyst slurry containing a mixture including (a) a medium oil having as a main component, a branched, saturated aliphatic hydrocarbon having 16 to 50 carbon atoms, 1 to 7 tertiary carbon atoms, 0 quaternary carbon atoms, and 1 to 16 carbon atoms in the branched chains bonded to the tertiary carbon atom; and at least one of the tertiary carbon atoms is bonded to hydrocarbon chains with a chain length having 4 or more of carbon atoms in three directions, (b) a methanol synthesis catalyst; (c) a methanol dehydration catalyst; and (d) a methanol shift catalyst or a methanol dehydration/shift catalyst.
US08536384B2 Recovering ethanol sidedraw by separating crude product from hydrogenation process
A process for producing ethanol is disclosed, comprising the steps of hydrogenating acetic acid in a reactor in the presence of a catalyst to form a crude ethanol product, separating at least a portion of the crude ethanol product in a column into a first distillate comprising ethanol and a first residue comprising acetic acid and water, wherein a substantial portion of the water in the crude ethanol product that is fed to the column is removed in the first residue, and separating a portion of the ethanol mixture stream to the second distillation column to yield an ethanol product sidedraw, second residue comprising water and a second distillate comprising ethyl acetate. The water content of the ethanol product sidedraw may be further reduced to yield a stream having reduced water content.
US08536380B2 Triterpene-containing oleogel-forming agent, triterpene-containing oleogel and method for producing a triterpene-containing oleogel
The invention relates to an oleogel-forming agent which comprises at least one highly dispersed triterpene. The invention also relates to an oleogel which comprises a nonpolar liquid in an amount ranging from 80% by weight to 99% by weight based on the total weight of the oleogel and an oleogel-forming agent comprising a highly dispersed triterpene in an amount ranging from 1% by weight to 20% by weight based on the total weight of the oleogel. The invention also relates to a method for producing an oleogel.
US08536376B2 Method for removing halogen from liquid ammonia
A method for depleting halide ions from liquid ammonia, which comprises bringing the liquid ammonia into contact with a strongly basic ion exchanger, where the basic structure of the strongly basic ion exchanger is a covalently crosslinked polymer matrix and the content of ammonia in the liquid ammonia is more than 98% by weight.
US08536374B2 Method for preparation of dicarboxylic acids from saturated hydrocarbons or cycloaliphatic hydrocarbons by catalytic oxidation
The present invention relates to a method for preparing dicarboxylic acids from saturated and cycloaliphatic hydrocarbons by oxidation at a reaction temperature comprised in the range of 25 to 300° C. in an autoclave using a solid heterogeneous catalyst. More particularly, the method of the invention relates to a method for preparing adipic acid (AA) from cyclohexane (CH) by selective oxidation.
US08536371B2 Carbon dioxide scrubbing using ionic materials
One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines, aryl amines or tertiary amines. The TSILs may be used for gas capture, capitalizing on their non-volatile nature. In certain embodiments, the captured gas is selected from the group consisting of CO2, SO2, CS2, and NO2. Another aspect of the present invention relates to a library of CO2-philic salts, which library facilitates reactive gas separation. In certain embodiments, the CO2-philic salts are CO2-reactive TSILs. In certain embodiments, the CO2-philic salts are resinous or plastic in nature.
US08536362B2 β-hydroxy-γ-aminophosphonates and methods for the preparation and use thereof
The present invention provides β-hydroxy-γ-aminophosphonates, β-amino-γ-aminophosphonates, and analogs thereof that inhibit carnitine acyltransferases. The invention also provides compositions comprising these β-hydroxy-γ-aminophosphonates, β-amino-γ-aminophosphonates, and analogs, and methods of the use of such compounds and compositions in the treatment, amelioration or prevention of pathological conditions, diseases or disorders that are linked with fatty acid metabolism, such as non-insulin dependent diabetes or obesity. The invention also provides processes for the preparation of such compounds and compositions.
US08536360B2 Compositions and methods for stereoselective aldehyde allylation and crotylation
Compositions and methods for practical, stereoselective allylation and crotylation for aldehyde substrates are described. The compositions and methods comprise reagents for allylation and/or crotylation and acids. In some embodiments, the reagents and acids are pre-mixed.
US08536359B2 Alkoxysilane compounds having fluoroalkyl group and method of preparing the same
Disclosed are alkoxysilane compounds having two fluoroalkyl groups and represented by the following general formula (1): wherein Rf and Rf′ are each a fluoroalkyl group of 1 to 10 carbon atoms, R1 is a hydrogen atom or an aliphatic monovalent hydrocarbon group of 1 to 6 carbon atoms, R2 and R3 are each methyl group or ethyl group, X and Y are each an ether linkage or an ester linkage, a and b are each 0 or 1, m, n and p are each an integer of 0 to 6, q is an integer of 1 to 6, and r is an integer of 0 to 2. By treating an inorganic material with the alkoxysilane compound having ether linkage and two fluoroalkyl groups, high water and oil repellency and high sliding properties can be imparted to the inorganic material. The alkoxysilane compounds can be easily purified, owing to enhancement of volatility by the branched structure.
US08536357B2 Process for heterogeneously catalysed esterfication of fatty acids
The invention relates to a process for esterifying free fatty acids in vegetable and animal fat with alcohols over heterogeneous acidic ion exchange resin catalysts at temperatures of 60 to 120° C.
US08536354B2 Steroidal ligands and their use in gene switch modulation
The present invention relates to steroidal ligands for use in nuclear receptor-based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions.
US08536351B2 2-aryl-5-heterocyclyl-cyclohexane-1,3,dione compounds and their use as herbicides
Cyclohexanedione compounds of Formula (I) wherein R1 is methyl, ethyl, n-propyl, iso-propyl, cyclopropyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, R2 and R3 are, independently hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy, C1-C6haloalkoxy, C2-C6alkenyl, C2-C6haloalkenyl, C2-C6alkynyl, C3-C6alkenyloxy, C3-C6haloalkenyloxy, C3-C6alkynyloxy, C3-C6cycloalkyl, C1-C6alkylthio, C1-C6alkylsulfinyl, C1-C6alkylsulfonyl, C1-C6alkylsulfonyloxy, C1-C6haloalkylsulfonyloxy, cyano, nitro, phenyl, phenyl substituted by C1-C4alkyl, C1-C3Cahaloalkyl, C1-C3alkoxy, C1-C3haloalkoxy, cyano, nitro, halogen, C1-C3alkylthio, C1-C3alkylsulfinyl or C1-C3alkylsulfonyl, or heteroaryl or heteroaryl substituted by C1-C3Calkyl, d.Cahaloalkyl, C1-C3alkoxy, C1-C3haloalkoxy, cyano, nitro, halogen, C1-C3alkylthio, C1-C3alkylsulfinyl or C1-C3alkylsulfonyl, R4 is hydrogen, methyl, ethyl, n-propyl, iso-propyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, X is O, S, S(O) or S(O)2, R5 is hydrogen or methyl, R6 is hydrogen, methyl or ethyl, or forms a double bond, which links the carbon atom, to which R6 is attached, with the adjacent carbon atom of R7 or R8, R7 and R8 are independently of each other C1-C5alkylene, which is unsubstituted or substituted by methyl or ethyl, or C2-C5alkenylene, which is unsubstituted or substituted by methyl or ethyl, and G is hydrogen, an alkali metal, alkaline earth metal, sulfoniυm, ammonium or a latentiating group, are suitable for use as herbicides.
US08536347B2 Photoacid generator, chemically amplified resist composition including the same, and associated methods
A photoacid generator represented by Formula 1 or Formula 2: wherein R1, R2, and R3 are each independently a C1-C10 alkyl group, X is a C3-C20 alicyclic hydrocarbon group forming a ring with S+, and at least one CH2 group in the alicyclic hydrocarbon group may be replaced with at least one selected from the group consisting of S, O, NH, a carbonyl group, and R5—S+A−, where R5 is a C1-C10 alkyl group, and A− is a counter-ion.
US08536346B2 Process or making N-hydroxy-3[4-[[[2-(2methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide and starting materials therefor
N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide and starting materials therefore are prepared by new synthetic methods.
US08536343B2 Arylamidine derivative, salt thereof and antifungal agent containing those
Disclosed is an arylamidine derivative represented by the following general formula: (wherein R1 and R2 independently represent an optionally substituted C3-4 alkyl group) or a salt thereof, which is useful as an antifungal agent.
US08536341B2 Primary allylic alcohol and Ag
The invention relates to a process of reacting a primary allylic alcohol with a compound containing a) a metal selected from the group consisting of Ag, Au, Ce, Mn, Ni, Ru, Re, Zn and Co preferably Ag and b) an oxidant like TEMPO (2,2′,6,6′-tetra-methylpiperidin-1-oxyl) or its derivates and c) a co-oxidants selected from the group of peroxodisulfates (PDS), H2SO5, H2O2, NaOCl, O2, KOCl, and air.
US08536339B2 AZA-indoles and related compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
The present invention provides compounds are disclosed herein having the formula: Wherein n is 1 or 2; m is 0 or 1; p is 0, 1 or 2; R1 is aryl, heteroaryl or alkyl; R2 is C1-6 hydrocarbyl, alkylacyl or hydroxyalkyl; R3 is aryl, heteroaryl, or alkyl; R4 is H, OH, —O—(C1-6 alkyl), —NH—(C1-6 alkyl), or oxide; R5 is H, halogen, C1-6 alkyl, O—(C1-6 alkyl), aryl, heteroaryl, —C(═O)(C1-6 alkyl), substituted or un-substituted oxazolin-2-yl; X═O, NH, —C(═O)— or —N═CH—; and Each L is independently alkylene and carbonyl. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
US08536336B2 Prodrug compounds useful as cannabinoid ligands
The present invention provides for compounds of formula (I) wherein A2, L2, R1g, R2A, R3A, R4A, R1a, R1b, q1, and z are as defined in the specification, are prodrugs of CB2 receptors ligands and as such are useful in the prevention and treatment of various diseases and conditions including, but not limited to, pain.
US08536335B2 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound
The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms.
US08536332B2 Modulating signal transduction pathways with substituted pyridol [2,3-b] pyrazines
Method of modulating ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and/or SAPK signal transduction pathway with a pyrido[2,3-b]pyrazine of formula (Ia).
US08536331B2 N-alkoxyamides of 6-(trisubstituted phenyl)-4-aminopicolinates and their use as selective herbicides for crops
N-Alkoxyamides of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are selective herbicides for corn, canola and sugar beet.
US08536330B2 Intermediates for the preparation of HMG-CoA reductase inhibitors
The present invention provides a process for preparing novel intermediates of Formula wherein, R1 can be hydrogen, C1-C4 alkyl, halogen, nitro, hydroxy, or C1-C4 alkoxy; Rx can be selected from hydrophobic residue of HMG-CoA reductase inhibitors; which can be effectively used for the preparation of HMG-CoA reductase inhibitors such as rosuvastatin and pharmaceutically acceptable salts thereof.
US08536324B2 Method of drug delivery by carbon nanotube-chitosan nanocomplexes
Functionalized Single Wall Carbon Nanotube (SWCNT) complexed with nanochitosan for use in the delivery of bioaffecting substances and diagnostic applications. fSWCNT complexed with the chitosan NG042 were used for delivery of DNA-encoding EGFP reporter protein and peptide. The results demonstrate that shown CNT-chitosan hybrid nanoparticles exhibit significantly higher transfection efficiency in vivo than chitosan alone. Furthermore, the functionalized nanotubes were tested for peptide transfer into HEK293 cells. The results showed that the hybrid nanoparticles efficiently transferred peptides. Together, these results show that hybrid SWCNT-chitosan particles increase DNA and peptide transfer into cells.
US08536322B2 Method for nucleic acid isolation by solid phase reversible binding of nucleic acids
The invention includes a method for separating polynucleotides, such as DNA, RNA and PNA, from a solution containing polynucleotides by reversibly and non-specifically binding the polynucleotides to a solid surface having a functional amide group-coated surface. The materials containing a solid surface can be in the form of microparticles, fibers, beads, membranes, test tubes, pipette tips or microwells and can further comprise a magnetic core portion. The pH, salt and concentration of crowding reagent, such as polyethylene glycol or alcohol, of the solution is adjusted to levels which result in nucleic acid binding to the solid surface. The magnetic microparticles with bound polynucleotides are separated from the solution under mild alkaline conditions and the nucleic acids are eluted from the magnetic microparticles. Solutions having different nucleic acid concentrations can be normalized by restricting the availability of the solid phase surface.
US08536320B2 Tetrahydropyran nucleic acid analogs
The present disclosure describes tetrahydropyran nucleoside analogs, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, novel tetrahydropyran nucleoside analogs are provided having at least one chiral substituent that are expected to be useful for enhancing one or more properties of oligomeric compounds such as nuclease resistance and/or binding affinity. In certain embodiments, the oligomeric compounds are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
US08536309B2 Methods of producing anti-IL-22RA antibodies
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
US08536307B2 Anticalins
The invention relates to the production of novel proteins exhibiting binding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. Like immunoglobulin, the anticalin thus obtained can be used to identify or bind molecular structures.
US08536297B2 Coating composition
The present invention relates to a coating composition. More particularly the present invention relates to a coating composition comprising an amine curative composition comprising a bis-aromatic secondary diamine, a bis-aromatic primary diamine and optionally a mono-aromatic primary diamine.
US08536293B2 Biomaterial
The present invention provides a triblock copolymer and a viscoelastic biostable foam comprising the same.
US08536292B2 Method of producing an impact-resistant thermoplastic resin
The invention concerns a process to manufacture a thermoplastic resin charged with mineral or carbonated matter, and possibly containing an organic impact modifier, through the introduction into the said resin of a comb polymer with at least one ethylenic unsaturation monomer, to which is grafted at least one polyalkylene oxide function. The resins then obtained which also form the subject of the invention have an improved impact resistance without their rigidity being degraded.
US08536289B2 Process for the production of polyolefin films
A process for the production of a corona-treated polyolefin film comprising the gas-phase polymerization of one or more α-olefins in the presence of a polymerization catalyst and an antistatic agent having a molecular weight higher than 500, said antistatic agent being fed at any stage of the polymerization process in an amount from 30 to 500 ppm weight based on the weight of the produced polyolefin.
US08536286B2 Composite catalyst for production of polyethylene
A composite catalyst useful in the production of polyethylene, which comprises at least a first catalyst and a second catalyst separated by a polymer layer, with the first catalyst and the second catalyst being identical or different, is described. A composite catalyst useful in the production of polyethylene with a broad molecular weight distribution in a single polymerization reactor, which comprises at least a first catalyst and a second catalyst separated by a polymer layer, with the first catalyst and the second catalyst being different, is also described. A process for preparing said catalysts and a process for the production of a polyethylene by using said catalysts are also described.
US08536285B2 Semi-continuous method for producing copolymers
A process for the preparation of a copolymer in semicontinuous operation in a polymerization apparatus including a polymerization reactor connected to a metering device, acid monomer being initially taken in the metering device and polyether macromonomer and water in the polymerization reactor, acid monomer being metered from the metering device via an acid monomer metering line into the polymerization reactor, a portion of the copolymer-containing aqueous medium being passed continuously during the free radical polymerization from the polymerization reactor via a reaction mixture line which is connected via a mixing device to the acid monomer metering line, the discharged copolymer-containing aqueous medium being mixed with the acid monomer in the mixing device during the metering of the acid monomer and being recycled to the polymerization reactor after the mixing via the acid monomer metering line.
US08536281B2 Method for synthesizing supramolecular materials
The present invention relates to a method for synthesizing a supramolecular material comprising: 1—the reaction of at least one carboxylic diacid, or ester or chloride of such a diacid, with, on the one hand, at least one modifier compound bearing both reactive functional groups capable of reacting with the carboxylic acid, ester or acid chloride functional groups and associative groups capable of associating with one another by hydrogen bonds, in a molar ratio of the reactive functional groups to the carboxylic acid, ester or acid chloride functional groups of between 0.10 and 0.50, and, on the other hand, at least one polyamine, said reactions being carried out successively or simultaneously, and 2—the reaction of the polyamide obtained at the end of step 1 with urea. The present invention also relates to the resulting material, and also to the uses thereof.
US08536280B2 Star polymer and coupling agent for anionic polymerization
[PROBLEM] To provide a novel star polymer useful as resist materials with high sensitivity and high resolution, and a novel coupling agent for anionic polymerization for synthesizing the polymer.[MEANS FOR SOLVING THE PROBLEM] A star polymer comprising: a core part derived from a coupling agent for anionic polymerization composed of an acid-degradable compound having an organic group derived from a halide; and an arm part that is attached to the core part and composed of an acid-degradable polymer chain obtained by anionic polymerization; and the coupling agent for anionic polymerization.
US08536277B2 Catalyst systems and their use for metathesis reactions
A novel process for reducing the molecular weight of nitrile rubber in the presence of specific catalyst systems containing the metathesis catalyst and also a specific addition of fluorine-containing boron compounds is provided.
US08536271B2 Thermoplastic elastomer composition
An object of the present invention is, in a thermoplastic elastomer composition in which a modified rubber is dispersed and filled in an ethylene-vinyl alcohol copolymer matrix in order to improve the low-temperature durability of the ethylene-vinyl alcohol copolymer, to reduce the extrusion load during extrusion molding thereof into a film without deteriorating the low-temperature durability. The present invention is a thermoplastic elastomer composition comprising an ethylene-vinyl alcohol copolymer (A) and a modified rubber (B) dispersed in the ethylene-vinyl alcohol copolymer (A), wherein the modified rubber (B) has an acid anhydride group or epoxy group and is dynamically cross-linked by a compound (C) having at least two amino groups. This thermoplastic elastomer composition can be suitably used in the production of an inner liner of a pneumatic tire.
US08536267B2 Surface modification of polymer particles
Methods of surface modification of polymer particle are useful in the development of marking fluids. The surface modification includes saponifying one or more acrylic ester groups on a surface of the polymer particle.
US08536262B2 Tire tread base containing syndiotactic-1,2-polybutadiene with diverse carbon blacks
The invention relates to a pneumatic tire having a cap/base configuration comprised of an outer tread cap rubber layer, with a tread running surface, and an underlying tread base rubber layer, where the base rubber layer contains syndiotactic polybutadiene with a diverse blend of carbon blacks.
US08536260B2 Resin composition for seamless air bag covers, and seamless air bag covers or seamless instrument panels with air bag covers, made by using the composition
A resin composition for a seamless air bag cover or a resin composition for a seamless instrument panel having an air bag cover which comprises (A) 50 to 90% by mass of polypropylene, (B) 0 to 20% by mass of a thermoplastic elastomer and (C) 10 to 30% by mass of talc having an average particle diameter of 15 to 25 μm and a distribution of a particle diameter such that the content of particles having a diameter of 5 μm or smaller is 10% by mass or smaller and the content of particles having a diameter exceeding 40 μm is 10% by mass or smaller. The resin composition exhibits sufficient properties when an instrument panel is molded. A seamless instrument panel having an air bag cover can be obtained as an integrally molded product, which can be treated as a single article in recycling.
US08536253B2 Method for producing rubberized concrete using waste rubber tires
Catalytic partial oxidation using a metal oxide catalyst surface treats crumb rubber that is recovered from waste rubber tires. Advantages of using catalytically oxidized crumb rubber relative to using non-catalytically oxidized crumb rubber in making the rubberized concrete, includes superior mechanical strength and water-repealing capability, lower oxidation temperature and shorter oxidation time, and accelerated hydration times. Rubber oil (a gas condensate) co-produced from the crumb rubber partial oxidation process is equal to or better than the commercial superplasticizers. Industrial scale partial oxidation employs a continuous flow tubular reactor where a crumb rubber/catalyst mixture is fed into the reactor co-currently with an air/nitrogen mixture.
US08536250B2 Geopolymer and epoxy simultaneous interpenetrating polymer network composition, and methods for the same
A simultaneous interpenetrating polymer network—geopolymer epoxy composition includes a first component comprised of a waterborne epoxy curing agent, an aluminosilicate source, and an amorphous silica, and a second component comprised of an epoxy resin and an alkaline silicate solution. The two components are mixed to produce a SIN-GE composition that cures at ambient temperatures. The SIN-GE composition may be a low-viscosity, sprayable composition, or may be a higher-viscosity composition. The compositions may be used as coatings, adhesives, mortars, casting materials, and the like.
US08536249B2 Elastomer composite and method for producing it
An elastomer composite includes the coagulated product of a mixture of a particulate slurry and a latex blend comprising skim latex and at least one of field latex and latex concentrate.
US08536248B2 Reinforced thermoplastic resin composition and molded article
The reinforced thermoplastic resin composition of the present invention includes: 50 to 90% by weight of a polycarbonate resin (A); 10 to 50% by weight of a graft copolymer mixture (B) (provided that a total amount of the component (A) and the component (B) accounts for 100% by weight) which is obtained by graft-polymerizing an aromatic alkenyl compound monomer unit (a) and a vinyl cyanide compound monomer unit (b) onto a rubber polymer (B1); and 6 to 22 parts by weight of an inorganic filler (D) which has been surface-treated with a water-soluble polyamide, relative to the total of 100 parts by weight of the polycarbonate resin (A) and the graft copolymer mixture (B). There is provided a reinforced thermoplastic resin composition exhibiting excellent moldability, generates a minimal amount of gas during molding, and also being capable of improving the rigidity of the resulting molded article and the impact resistance when dropping the product.
US08536243B2 Two-component system for bone cement
The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.
US08536242B2 Photocurable composition
The present invention provides a photocurable composition which contains a photobase generator capable of generating a satisfactory amount of a base in a high quantum yield when irradiated even with a small quantity of light for a short time, and contains a curable compound that is rapidly cured by the generated base such that the composition is cured into a cured product. The photocurable composition comprises: a photobase generator (A) which is a salt of a carboxylic acid (a1-1) represented by the following formula (1-1) with a basic compound (a2), and a curable compound (B) which has, in one molecule thereof, at least two functional groups selected from among epoxy group, (meth)acryloyl group, isocyanato group, acid anhydride group, and alkoxysilyl group, where R1 to R7 in the above formula (1-1) each are hydrogen or an organic group, R1 to R7 may be the same or different, and two of R1 to R7 may be bonded to each other to form a ring structure.
US08536239B1 Method for producing improved rubberized concrete using waste rubber tires
Partial oxidation of crumb rubber derived from environmental hazardous waste tires yields surface treated crumb rubber which are used as blending stocks for making rubberized concrete with substantially improved mechanical strength as compared to the conventional rubberized concrete. The chemically more active rubber surface becomes hydrophilic, so it interacts with the hydrophilic surface of surrounding cement matrix much stronger. The mechanically improved rubberized concrete is more versatile than conventional rubberized concrete.
US08536237B2 Ionomeric membrane
An ionomeric membrane formed of a sulphonic (per)fluorinated ionomer wherein the sulphonic groups are at the end of short side chains (SSC), said ionomer having: equivalent weight between 700 and 1600 g/eq; side chains of formula: —O—CF2—CF2—SO3−M+, wherein M is hydrogen or an alkaline metal; said membrane having the following combination of properties: size variations, for both the orthogonal directions xy of the plane, lower than 15%, measured after dipping of the ionomeric membrane, dried at 105° C. under vacuum for one hour, in demineralized water at 100° C. for 30 minutes; the membrane, dipped at the temperature of 50° C. for 22 hours in a water/ethanol mixture containing 40% by weight of alcohol, remains integral.
US08536228B2 Transdermal compositions
The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.
US08536225B2 Therapeutic methods employing nitric oxide precursors
Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic applications, relating to a human carbamyl phosphate synthetase I polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from mRNA, it is possible to type a human carbamyl phosphate synthetase I with regard to the human carbamyl phosphate synthetase I polymorphism, for example, in the context of diagnosing and treating hepatic veno-occlusive disease (HVOD) associated with bone marrow transplants.
US08536224B2 Pharmaceutical and nutraceutical compositions of abscisic acid
The invention relates to compositions comprising abscisic acid, and/or salts, derivatives and analogs thereof, and methods of pharmaceutical and/or nutraceutical use.
US08536220B2 Supplement composition and method of use
The present invention relates to a dietary supplement composition made of: linolinic expeller pressed soybean oil in the range of 65%-85%, Omega 3 (18/12) fish oil 15%-35%, and 1%-20% alpha-tocopherol and a method to use this composition to supplement the diet of a domestic animal, such as a canine or an equine.
US08536217B2 Radiation curable compositions
A polymerizable Norrish Type II photoinitiator according to Formula (I): Radiation curable compositions and inkjet inks containing the polymerizable Norrish Type II photoinitiator of Formula (I) exhibit improved compatibility with and solubility in radiation curable compositions and inkjet inks, and exhibit low extractable amounts of the photoinitiator and its residues after curing.
US08536214B2 Indane derivatives as AMPA receptor modulators
The present invention relates to a heterocyclic derivative according to formula (I); wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer's disease.
US08536213B2 Oligomer-dantrolene conjugates and related compounds
The invention relates to (among other things) oligomer-dantrolene conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered compounds.
US08536211B2 Process for the preparation of 5-substituted 1-alkyltetrazoles
The present invention relates to a process for the preparation of 5-substituted 1-alkyltetrazoles.
US08536210B2 Compounds for inhibiting semicarbazide-sensitive amine oxidase (SSAO)/vascular adhesion protein-1 (VAP-1) and uses thereof for treatment and prevention of diseases
The present invention relates to compounds of general formula (i) having an oxime moiety or a pharmaceutically acceptable salt, hydrate or solvate thereof and its use for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1), a pharmaceutical composition comprising the compound or a salt, hydrate or solvate thereof as an active ingredient, a method for the prevention or the treatment of a SSAO/VAP-1 related disease, said diseases including acute or chronic inflammatory diseases, diseases related to carbohydrate metabolism, diabetes-associated complications, diabetic retinopathy and macular oedema, diseases related to adipocyte or smooth muscle dysfunctions, neurodegenerative diseases and vascular diseases.
US08536208B2 Antifungal composition
A pharmaceutical composition for oral administration which is self-emulsifying on contact with an aqueous phase, in particular gastrointestinal fluids, and which comprises: (a) an antifungally active compound of formula (I) wherein R1, R2 and R3 are independently of one another hydrogen, F or Cl; or a pharmaceutically acceptable acid addition salt thereof, and (b) a carrier comprising a solubilizer component for the antifungally effective component (a).
US08536207B2 Method for treating a keratoconjunctival disorder
A method for treating a keratoconjunctival disorder, wherein the keratoconjunctival disorder comprises at least one disorder selected from the group consisting of a superficial punctate keratopathy, a corneal epithelial defect, corneal erosion, a corneal ulcer, a conjunctival epithelial defect, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis and conjunctivitis, and wherein the method comprises orally administering from 3 mg/kg to 30 mg/kg per day of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof to a patient in need thereof.
US08536206B2 Process for the preparation of roflumilast
The invention relates to novel processes for the preparation of high-purity roflumilast.
US08536203B2 Pharmaceutical compounds
This invention relates to novel substituted nitrocatechol derivatives, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them.
US08536199B2 Oral combination of vitamins
This invention provides compositions for treating and preventing nausea and other disorders, the compositions comprising vitamins as active ingredients, including vitamin B6, vitamin K, and vitamin C, and a method for treating nausea or morning sickness with the oral compositions.
US08536198B2 Piperidine derivatives as modulators of chemokine receptor activity
The present application describes modulators of MIP-1 of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as set forth above. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators are disclosed.
US08536196B2 Substituted 1,3-dioxanes useful as PPAR modulators
Specifically useful stereoisomers of 1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections as well as their use in the treatment of a disease related to TP, such as cardiovascular diseases.
US08536195B2 Bicyclic derivatives as modulators of ion channels
The present invention relates to bicyclic compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
US08536192B2 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
A novel compound which is useful as an agent for treating and/or preventing emesis, vomiting and/or constipation.A compound represented by the formula (I): wherein R1 and R2 are each independently hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted cycloalkyl, optionally substituted aryl etc., R3 is hydrogen, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl, optionally substituted lower alkoxy etc., R4 is hydrogen or lower alkyl, R5 is hydrogen, lower alkyl, cycloalkyl lower alkyl or lower alkenyl, or a pharmaceutically acceptably salt, or a solvate thereof is provided.
US08536191B2 Crystalline and amorphous forms of nalbuphine hydrochloride
The present invention is directed to novel crystalline and amorphous forms of nalbuphine hydrochloride.
US08536190B2 Treating unwanted ocular conditions using an ascomycin macrolactam
The present invention provides compositions and uses of an ascomycin macrolactam for the treatment of an unwanted ocular condition occurring in a patient undergoing treatment with a therapeutically active agent for the treatment of cancer.
US08536188B2 Dosing regimens for treatment of proliferative disorders comprising administration of sapacitabine
One aspect of the present invention relates to the use of sapacitabine, or a metabolite thereof, in the preparation of a medicament for treating a proliferative disorder, wherein the sapacitabine or metabolite thereof is administered in a dosing regimen comprising at least one treatment cycle, wherein said treatment cycle comprises administering a therapeutically effective amount of sapacitabine or metabolite thereof for about 2 to about 6 days per week, for 2 weeks out of 3 weeks. Another aspect of the invention relates to the use of sapacitabine, or a metabolite thereof, in the preparation of a medicament for treating cutaneous T-cell lymphoma (CTCL).
US08536187B2 2,4,6-trisubstituted pyrido(3,2-d)pyrimidines useful for treating viral infections
Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (Ia): wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro-drugs thereof, for use in the treatment of hepatitis C.
US08536186B2 Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
US08536179B2 Indoles
Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful in treating cancer.
US08536177B2 Therapeutic agents useful for treating pain
A compound of formula: wherein Ar1, A, R3, x, and m are as disclosed herein and Ar2 is a benzothiazolyl, benzooxazolyl, or benzoimidazolyl group or a pharmaceutically acceptable salt thereof (a “Benzoazolylpiperazine Compound”), compositions comprising a Benzoazolylpiperazine Compound, and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Benzoazolylpiperazine Compound are disclosed.
US08536174B2 Urotensin II receptor antagonists
The invention is directed to Urotensin II antagonists. More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating Urotensin-II mediated disorders. Pharmaceutical and veterinary compositions and methods of treating cardiovascular disorders and various other disease states or conditions using compounds of the invention are also described.
US08536172B2 Inhibitors of JNK
The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein p, q, Y′, r, R1, R2, X, X1, X2, X3, and X4 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
US08536171B2 Method for obtaining 5-amino 2,3-dihydrophthalazine-1,4-dione alkali metal salts and their use in medicine
The invention is related to a method for preparing 5-amino-2,3-dihydrophthalazine-1,4-dione salt with alkali metals of the formula II wherein 5-nitro-2,3-dihydrophthalazine-1,4-dione is solved in water solution of MOH1 where M has the below mentioned meaning, with formation of solution of 5-nitro-2,3-dihydrophthalazine-1,4-dione alkali metal salt, which is catalytically transformed into 5-amino-2,3-dihydrophthalazine-1,4-dione salt at the temperature 40-900C by means of hydrogen under the pressure 1-4 MPa in at the presence of a transition metal catalyst (Pt, Pd) on activated carbon, and separation of crystalline 5-amino-2,3-dihydrophthalazine-1,4-dione salt is performed by water solution diluting with lower alcohol or cyclic lower ether with cooling to the temperature −5° C. to −15° C., providing that there is used 5-nitro-2,3-dihydrophthalazine-1,4-dione formed in the reaction of anhydride of 3-nitrophthalic acid with hydrazine hydrate in anhydrous acetic acid at the temperature 100-110° C. with distilling the mixture of acetic acid and water off. There was also presented a pharmaceutical composition containing such obtained 5-amino-2,3-dihydrophthalazine-1,4-dione salt with alkali metals and its application in medicine. There was also presented new use of 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt for production of a drug for treatment of heart diseases, pancreas diseases and diabetes as well as application of sodium salt optionally in combination with lithium salt for treatment of the nervous system diseases. Besides, the methods of treatment of these diseases were also presented Formula II where M represents Li, Na, K.
US08536170B2 Curable composition comprising a di-isoimide, method of curing, and the cured composition so formed
The present invention deals with a novel curable epoxy composition comprising an aromatic di-isoimide chemical compound. The di-isoimide serves effectively as a thermally activated latent catalyst in epoxy curing, thereby increasing shelf life, and avoids premature cross-linking. Novel laminated articles and printed wiring boards, including encapsulated printed wiring boards are also disclosed.
US08536168B2 Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway
The present disclosure relates to compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders; specifically relating to compounds of formula I:
US08536167B2 Methods for treating ophthalmic, otic, or nasal infections
The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition comprising finafloxacin or a finafloxacin derivative. The present invention also relates to antimicrobial compositions comprising finafloxacin or a finafloxacin derivative. The compositions are suitable for the treatment of ophthalmic, otic, or nasal infections.
US08536164B2 Fused pyridine compounds as casein kinase inhibitors
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, A, R4, n, and R7 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
US08536156B2 Contraception process and administration form for the same
A method for hormonal contraception comprising administering at least one contraceptive hormone in a plurality of linked taking periods optionally having a sequence lasting several years. Each taking period comprises at least one taking cycle. Each taking cycle comprises a duration-constant taking phase lasting several days and a taking pause lasting several days. In each taking phase the hormonal component is administrated in a daily unit. In each taking pause either a placebo or no unit is administered. The duration of the taking phase or phases of at least the final taking period is at least 22 days. The duration of each taking phase in any taking period preceding a following taking period is shorter than that in each of the taking phases in each following taking period.
US08536154B2 Composition for activating mitochondria
The present invention relates to a composition for activating mitochondria which contains a chitooligosaccharide as an active constituent. The chitooligosaccharide can increase the activity of mitochondrial enzymes and increase the amount of mitochondrial DNA, and thus it can be suitably used as an active constituent in the composition for activating mitochondria.
US08536153B2 Chemical synthesis of phosphatidylinositol mannoside glycans from Mycobacterium tuberculosis
The efficient synthesis of phosphatidylinositol mono- to hexa-mannoside (PIM1 to PIM6) is reported. The invention relates to these phosphatidylinositol mono- to hexa-mannosides carrying a linker and a reactive functional group, e.g. the sulfhydryl group, a protein, a fluorescent probe, or a solid phase. The invention further relates to vaccines comprising the PIMs linked to a carrier protein or an antigen.
US08536151B2 Process for preparing lamivudine polymorph form
The invention relates to a process for the preparation of stable lamivudine polymorph form and to a composition comprising thereof.
US08536147B2 Antibacterial antisense oligonucleotide and method
A method for enhancing, by at least 10 fold, the antibacterial activity of an antisense oligonucleotide composed of morpholino subunits linked by phosphorus-containing intersubunit linkages. The method includes one or both of: conjugating an arginine-rich carrier to a 3′ or 5′ end of the oligonucleotide and modifying the oligonucleotide to contain 20%-50% intersubunit linkages that are positively charged at physiological pH. Also disclosed is an antisense oligonucleotide having enhanced antibacterial activity by virtue of one or both modifications.
US08536146B2 Cytoplasmic BKCa channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons
The invention relates to a method of modulating neuronal function by modulating the cytoplasmic level in a neuron of an intron-containing mRNA. The methods are useful in diagnostic, research and therapeutic applications.
US08536142B2 Spinosyns for wound healing
A spinosyn or a physiologically acceptable derivative or salt thereof for promoting or accelerating wound healing in humans.
US08536139B2 Compositions comprising lipoteichoic acid for use in treating pleural effusion or pneumothorax
The present invention relates to lipoteichoic acid T for use in treating pleural effusion or pneumothorax. The present invention also relates to the use of lipoteichoic acid T (LTA-T) in the manufacture of a medicament for treating pleural effusion or pneumothorax. The present invention also relates to a kit comprising a pharmaceutical composition comprising lipoteichoic acid T and instructions indicating that the composition is for use as a pleurodesis agent. In addition, the present invention relates to a method of treating pleural effusion or pneumothorax comprising administration of lipoteichoic acid T to a subject.
US08536138B2 Treatment of pulmonary hypertension with carbonic anhydrase inhibitors
This disclosure relates generally to methods and pharmaceutical compositions useful in treating pulmonary hypertension. In one embodiment, for example, the disclosure provides a method for treating pulmonary hypertension comprising administering a therapeutically effective dose of a carbonic anhydrase inhibitor to a patient in need of treatment. The disclosure finds utility in the fields of medicine and pharmacology.
US08536136B2 Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
The present invention relates to compounds of formula I: or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
US08536132B2 Lymphatic zip codes in tumors and pre-malignant lesions
Disclosed herein are compositions and methods for and involving selectively targeting tumor lymphatics.
US08536129B2 Treatment for anxiety
The invention provides methods of treating or effecting prophylaxis of a patient having or at risk of developing symptoms of anxiety in which an effective regime of an agent that inhibits specific binding of PSD95 to an NMDA receptor is administered to a patient.
US08536126B2 Conjugated factor VIII molecules
The present invention relates to B-domain truncated Factor VIII molecules with a modified circulatory half life, said molecule being covalently conjugated with a hydrophilic polymer. The invention furthermore relates to methods for obtaining such molecules as well as use of such molecules.
US08536122B2 Acylated GLP-1 compounds
Protracted GLP-1 compounds and therapeutic uses thereof.
US08536117B2 Oxidant resistant apolipoprotein A-1 and mimetic peptides
A method for the treatment of cardiovascular disease or disorder in a subject in need thereof, the method comprising the steps of administering an ApoA1 mimetic that is capable of promoting cholesterol efflux from lipid loaded cells in the subject, wherein the ApoA1 mimetic has an amino acid sequence that includes at least a portion of the amino acid sequence of ApoA1 or a mimetic of ApoA1 that contains at least one tryptophan, at least one tryptophan from the ApoA1 or mimetic of the ApoA1 being substituted with an oxidant resistant amino acid in the amino acid sequence of the ApoA1 mimetic.
US08536114B2 Macrocycles
Disclosed herein are compounds of general formula (I): wherein A, B, R1 and R2 are as defined in the specification, and their use as pharmaceuticals.
US08536110B2 Molded solid industrial cleaning block
A method of manufacturing a detergent composition comprising combining a plurality of components suitable for producing a detergent block which is water soluble into a fluid mixture. A mold assembly is provided which has a first mold component and a second mold component. The first and second mold components define a mold assembly having a body and a bottom. The body includes an outer wall, a bottom and outer wall which defines a mold interior. The fluid mixture is presented into the mold assembly and allowed to harden into at least a partially solid state within the mold defining a solid soluble, consumable detergent block. Once the block is at least partially cured, the first and second mold components are separated exposing the solid soluble, consumable detergent block to the ambient environment. Water soluble indicia are positioned onto the soluble consumable detergent block.
US08536106B2 Ferric hydroxycarboxylate as a builder
The use of ferric hydroxycarboxylate as a chelator and builder for cleaning compositions is disclosed. The cleaning composition may be formulated for warewashing, laundering, and for other means of removing soils and includes a ferric hydroxycarboxylate, an alkalinity source and a surfactant system. The cleaning composition has a pH of between about 9 and about 12.
US08536104B1 Hand soap bar with tether
The hand soap bar with tether is a bar of hand soap having a built-in tether. The tether includes an elastic band that can be attached to a user's wrist. An anchor member is encased in the soap bar. One end of the tether is attached to the anchor member. An elastic loop defines the other end of the tether.
US08536100B2 Rapid method for identifying polypeptide-nucleic acid interactions
The invention relates to a method for analysing interactions of a nucleic acid with at least one polypeptide, comprising (a) providing a reaction vessel with a composition comprising cross-linked complexes comprising at least one nucleic acid and at least one polypeptide; (b) immobilizing at least part of the cross-linked complexes to the reaction vessel; (c) at least partially reversing said cross-links in said immobilized complexes by performing a heat incubation step thereby at least partially releasing the nucleic acids from the complexes; (d) analyzing the released nucleic acid. wherein steps (a) to (d) are performed in one reaction vessel. Also provided are specific reaction vessels and kits.
US08536097B2 4-(4-haloalkyl-3-thiobenzoyl)pyrazoles and use thereof as herbicides
A description is given of 4-(4-haloalkyl-3-thiobenzoyl)pyrazoles of the formula (I) and of their use as herbicides. In this formula (I), X, Y, R1, R2, R3, and R4 are radicals such as hydrogen and organic radicals such as alkyl.
US08536090B2 Use of natural extracts of tannin and non-tannin materials for improving soil fertility and providing a starter effect on cultivations, and a tannin and non-tannin phytocomposition therefor
A use of a tannin and non tannin material phytocomposition or phytocomplex, either in a dry or liquid form, applied to the seedling seeds or seedling agamic multiplication members, or to implanted seedlings, to promote the starter effect, i.e. strong stimulation of the seedling initial growth. The phytocomposition is made by leaching a biomass of one or more of the following species: Castanea spp., Juglans spp., Eucalyptus spp., Quercus spp., Salix spp., Vitis spp., Mimosa ssp., Schinopsis spp., Olea europaea, Onobrychis viciifolia, Rhamnus spp., Artemisia spp., Lawsonia inermis, either in a single form or in a mixture in all mixing ratios.
US08536089B2 Fungicidal compositions
The invention relates to fungicidal compositions comprising as active ingredient a combination of components A) and B) as defined in the patent claims, to a method of controlling phytopathogenic diseases on crop plants using such a compositions and to a method of protecting natural substances of vegetable and/or animal origin and/or their processed forms using such a composition.
US08536087B2 Thermographic imaging element
A thermographic substrate assembly comprised of a colorant and a flexible substrate. This assembly also contains a thermosensitive layer, and the thermosensitive layer contains a binder, a multiplicity of hollow sphere organic pigments, and a thermal solvent.
US08536085B2 Preparation of high activity cobalt catalysts, the catalysts and their use
A method is provided for preparing a supported cobalt-containing catalyst having substantially homogeneously dispersed, small cobalt crystallites. The method comprises depositing cobalt nitrate on a support and then subjecting the support to a two-step decomposition protocol. In the first step, the support is heated in an oxygen-containing, substantially water-free atmosphere to about 160° C. to form an intermediate decomposition product. This intermediate product is then or hydrolyzed and reduced, or hydrolyzed, calcined and reduced.
US08536084B2 Photocatalyst material, method for decomposition of organic material, interior member, air purification device, and apparatus for preparation of oxidizing agent
The present invention provides a tungsten trioxide microparticle carrying on its surface divalent copper salt. The divalent copper salt is utilized to perform a multi-electron reduction of oxygen. The tungsten trioxide exhibits a high oxidative decomposition activity when exposed to visible light.
US08536081B2 Supported polymerisation catalysts
Supported catalyst system for the polymerization of olefins, having at least two different monocyclopentadienyl transition metal compounds, one or more activators including an ionic compound having (i) a cation and (ii) an anion having up to 100 non-hydrogen atoms and the anion containing at least one substituent comprising a moiety having an active hydrogen, and one or more support materials. The supported “mixed or dual site” catalyst systems having different monocyclopentadienyl catalysts when activated by specific ionic activators lead to catalyst systems showing an improved balance of properties which may be used to prepare LLDPE polymers having broad melt flow ratios.
US08536079B2 Use of boron to reduce the thermal conductivity of unbonded loosefill insulation
An unbonded loosefill insulation material formed from a glass batch is provided. The glass batch comprises, in weight percent: 62.0-69.0% of SiO2, 0.0-4.0% of Al2O3, 7.0-12.0% of CaO, 0.0-5.0% of MgO, 3.0-14.0% of B2O3, 13.0-18.0% of Na2O and 0.0-3.0% of K2O. The unbonded loosefill insulation material is configured for distribution in a blowing insulation machine.
US08536076B1 Thermal energy resistant textile fleece fabric for use in safety apparel
A textile fleece fabric having a resistance to thermal energy from exposure to momentary electric arcs or flame so as to be suitable for use in safety apparel is made of three integrated layers including inner and outer layers on opposite sides of an intervening middle layer. The inner and outer layers are comprised predominately of textile fibers which have inherent or additive flame resistant properties, and the middle layer is comprised substantially entirely of textile fibers without inherent or additive flame resistant properties. The textile fibers of one of the inner or outer layers have a raised nap forming a fleece surface.
US08536075B2 Electronic systems incorporated into textile threads or fibres
A textile thread or fiber has a plurality of elements, such as electronic elements, embedded or encapsulated therein. The textile thread or fiber could also be part of a fabric article. The textile thread or fiber, for example, has the plurality of elements interconnected, or otherwise intercommunicating, with one another to form a signal processing system. This signal processing system may include, for example, a personal computer system, a personal telecommunications transmitter/receiver system or a personal television and/or radio system.
US08536074B2 Three dimensional structures useful as cleaning sheets
Disclosed are cleaning sheets having substantial macroscopic three-dimensionality. Optionally, the macroscopically three-dimensional cleaning sheets can comprise a contractable material (e.g., a scrim material), which when heated and then cooled contracts so as to provide a macroscopic, three-dimensional structure. Macroscopic three-dimensionality is described in terms of “average peak-to-peak distance” and “surface topography index”, as well in terms of “average height differential”. Also disclosed are cleaning implements comprising a handle and the described cleaning sheets. Processes for the sheets, benefits of the processes, and articles of manufacture are also disclosed.
US08536071B2 Gasket with positioning feature for clamped monolithic showerhead electrode
An electrode assembly for a plasma reaction chamber used in semiconductor substrate processing. The assembly includes an upper showerhead electrode which is mechanically attached to a backing plate by a series of spaced apart cam locks. A thermally and electrically conductive gasket with projections thereon is compressed between the showerhead electrode and the backing plate at a location three to four inches from the center of the showerhead electrode. A guard ring surrounds the backing plate and is movable to positions at which openings in the guard ring align with openings in the backing plate so that the cam locks can be rotated with a tool to release locking pins extending from the upper face of the electrode.
US08536069B2 Multilayered low k cap with conformal gap fill and UV stable compressive stress properties
The present disclosure provides a multilayered cap (i.e., migration barrier) that conforms to the substrate (i.e., interconnect structure) below. The multilayered cap, which can be located atop at least one interconnect level of an interconnect structure, includes, from bottom to top, a first layer comprising silicon nitride and a second layer comprising at least one of boron nitride and carbon boron nitride.
US08536068B2 Atomic layer deposition of photoresist materials and hard mask precursors
Methods for forming photoresists sensitive to radiation on substrate are provided. Atomic layer deposition methods of forming films (e.g., silicon-containing films) photoresists are described. The process can be repeated multiple times to deposit a plurality of silicon photoresist layers. Process of depositing photoresist and forming patterns in photoresist are also disclosed which utilize carbon containing underlayers such as amorphous carbon layers.
US08536064B2 Double patterning strategy for contact hole and trench in photolithography
A method of lithography patterning includes forming a first etch stop layer, a second etch stop layer, and a hard mask layer on a material layer. The materials of the first etch stop layer and the second etch stop layer are selected by the way that there is a material gradient composition between the second etch stop layer, the first etch stop layer, and the material layer. Hence, gradient etching rates between the second etch stop layer, the first etch stop layer, and the material layer are achieved in an etching process to form etched patterns with smooth and/or vertical sidewalls within the second and the first etch stop layers and the material layer.
US08536060B2 Method for clearing native oxide
A method for clearing native oxide is described. A substrate is provided, including an exposed portion whereon a native oxide layer has been formed. A clearing process is performed to the substrate using nitrogen trifluoride (NF3) and ammonia (NH3) as a reactant gas, wherein the volumetric flow rate of NF3 is greater than that of NH3.
US08536053B2 Method for restricting lateral encroachment of metal silicide into channel region
A method for restricting lateral encroachment of the metal silicide into the channel region, comprising: providing a semiconductor substrate, a gate stack being formed on the semiconductor substrate, a source region being formed in the semiconductor on one side of the gate stack, and a drain region being formed in the semiconductor substrate on the other side of the gate stack; forming a sacrificial spacer around the gate stack and on the semiconductor substrate; depositing a metal layer for covering the semiconductor substrate, the gate stack and the sacrificial spacer; performing a thermal treatment on the semiconductor substrate, thereby causing the metal layer to react with the sacrificial spacer and the semiconductor substrate in the source region and the drain region; removing the sacrificial spacer, reaction products of the sacrificial spacer and the metal layer, and a part of the metal layer which does not react with the sacrificial spacer.
US08536052B2 Semiconductor device comprising contact elements with silicided sidewall regions
When forming a metal silicide within contact openings in complex semiconductor devices, a silicidation of sidewall surface areas of the contact openings may be initiated by forming a silicon layer therein, thereby reducing unwanted diffusion of the refractory metal species into the laterally adjacent dielectric material. In this manner, superior reliability and electrical performance of the resulting contact elements may be achieved on the basis of a late silicide process.
US08536049B2 Method for forming metal contacts
Methods of forming metal contacts with metal inks in the manufacture of photovoltaic devices are disclosed. The metal inks are selectively deposited on semiconductor coatings by inkjet and aerosol apparatus. The composite is heated to selective temperatures where the metal inks burn through the coating to form an electrical contact with the semiconductor. Metal layers are then deposited on the electrical contacts by light induced or light assisted plating.
US08536048B2 Method of manufacturing electronic component
According to one embodiment, a lower wiring layer is formed by using a sidewall transfer process for forming a sidewall film having a closed loop along a sidewall of a sacrificed or dummy pattern and, after removing the sacrificed pattern to leave the sidewall film, selectively removing the base material with the sidewall film as a mask. One or more upper wiring layers are formed in an upper layer of the lower wiring layer via another layer using the sidewall transfer process. Etching for cutting each of the lower wiring layer and the upper wiring layers is collectively performed, whereby closed-loop cut is applied to the lower wiring layer and the upper wiring layers.
US08536046B2 Partitioned through-layer via and associated systems and methods
Partitioned vias, interconnects, and substrates that include such vias and interconnects are disclosed herein. In one embodiment, a substrate has a non-conductive layer and a partitioned via formed in a portion of the non-conductive layer. The non-conductive layer includes a top side, a bottom side, and a via hole extending between the top and bottom sides and including a sidewall having a first section a second section. The partitioned via includes a first metal interconnect within the via on the first section of the sidewall and a second metal interconnect within the via hole on the second section of the sidewall and electrically isolated from the first metal interconnect. In another embodiment, the first metal interconnect is separated from the second metal interconnect by a gap within the via hole.
US08536044B2 Protecting bond pad for subsequent processing
A method for opening a bond pad on a semiconductor device is provided. The method comprises removing a first layer to expose a first portion of the bond pad and forming a protective layer over the exposed first portion of the bond pad. The method further comprises performing subsequent processing of the semiconductor device and removing the protective layer to expose a second portion of the bond pad.
US08536041B2 Method for fabricating transistor with high-K dielectric sidewall spacer
A method is provided for fabricating a transistor. The transistor includes a silicon layer including a source region and a drain region, a gate stack disposed on the silicon layer between the source region and the drain region, and a sidewall spacer disposed on sidewalls of the gate stack. The gate stack includes a first layer of high dielectric constant material, a second layer comprising a metal or metal alloy, and a third layer comprising silicon or polysilicon. The sidewall spacer includes a high dielectric constant material and covers the sidewalls of at least the second and third layers of the gate stack. Also provided is a method for fabricating such a transistor.
US08536040B1 Techniques for using material substitution processes to form replacement metal gate electrodes of semiconductor devices with self-aligned contacts
Generally, the present disclosure is directed to techniques for using material substitution processes to form replacement metal gate electrodes, and for forming self-aligned contacts to semiconductor devices made up of the same. One illustrative method disclosed herein includes removing at least a dummy gate electrode to define a gate cavity, forming a work-function material in said gate cavity, forming a semiconductor material above said work-function material, and performing a material substitution process on said semiconductor material to substitute a replacement material for at least a portion of said semiconductor material.
US08536038B2 Manufacturing method for metal gate using ion implantation
A manufacturing method for a metal gate includes providing a substrate having at least a semiconductor device with a conductivity type formed thereon, forming a gate trench in the semiconductor device, forming a work function metal layer having the conductivity type and an intrinsic work function corresponding to the conductivity type in the gate trench, and performing an ion implantation to adjust the intrinsic work function of the work function metal layer to a target work function.
US08536036B2 Predoped semiconductor material for a high-K metal gate electrode structure of P- and N-channel transistors
In a process strategy for forming high-k metal gate electrode structures in an early manufacturing phase, a predoped semiconductor material may be used in order to reduce the Schottky barrier between the semiconductor material and the conductive cap material of the gate electrode structures. Due to the substantially uniform material characteristics of the predoped semiconductor material, any patterning-related non-uniformities during the complex patterning process of the gate electrode structures may be reduced. The predoped semiconductor material may be used for gate electrode structures of complementary transistors.
US08536035B2 Silicon-on-insulator substrate and method of forming
Silicon-on-insulator (SOI) structures and related methods of forming such structures. In one case, a method includes providing a silicon-on-insulator (SOI) handle substrate having: a substantially uniform resistivity profile along a depth of the handle substrate; and an interstitial oxygen (Oi) concentration of less than approximately 10 parts per million atoms (ppma). The method further includes counter-doping a surface region of the handle, causing the surface region to have a resistivity greater than approximately 3 kOhm-cm, and joining the surface region of the handle substrate with a donor wafer.
US08536034B2 Methods of forming stressed silicon-carbon areas in an NMOS transistor
Disclosed herein are various methods of forming stressed silicon-carbon areas in an NMOS transistor device. In one example, a method disclosed herein includes forming a layer of amorphous carbon above a surface of a semiconducting substrate comprising a plurality of N-doped regions and performing an ion implantation process on the layer of amorphous carbon to dislodge carbon atoms from the layer of amorphous carbon and to drive the dislodged carbon atoms into the N-doped regions in the substrate.
US08536033B2 SOI semiconductor device comprising a substrate diode and a film diode formed by using a common well implantation mask
When forming sophisticated SOI devices, a substrate diode and a film diode are formed by using one and the same implantation mask for determining the well dopant concentration in the corresponding well regions. Consequently, during the further processing, the well dopant concentration of any transistor elements may be achieved independently from the well regions of the diode in the semiconductor layer.
US08536031B2 Method of fabricating dual damascene structures using a multilevel multiple exposure patterning scheme
A method for fabricating a dual damascene structure includes providing a first photoresist layer coated on an underlying dielectric stack, exposing said first photoresist layer to a first predetermined pattern of light, coating a second photoresist layer onto the pre-exposed first photoresist layer, exposing said second photoresist layer to a second predetermined pattern of light, optionally post-exposure baking the multi-tiered photoresist layers and developing said photoresist layers to form a multi-tiered dual damascene structure in the photoresist layers.
US08536030B2 Semipolar semiconductor crystal and method for manufacturing the same
A method of manufacturing a semipolar semiconductor crystal comprising a group-III-nitride (III-N), the method comprising: providing a substrate comprising sapphire (Al2O3) having a first surface that intersects c-planes of the sapphire; forming a plurality of trenches in the first surface, each trench having a wall whose surface is substantially parallel to a c-plane of the substrate; epitaxially growing a group-III-nitride (III-N) material in the trenches on the c-plane surfaces of their walls until the material overgrows the trenches to form a second planar surface, substantially parallel to a (20-2l) crystallographic plane of the group-III-nitride, wherein l is an integer.
US08536029B1 Nanowire FET and finFET
A method includes thinning a first region of an active layer, for form a stepped surface in the active layer defined by the first region and a second region of the active layer, depositing an planarizing layer on the active layer that defines a planar surface disposed on the active layer, etching to define nanowires and pads in the first region of the active layer, suspending the nanowires over the BOX layer, etching fins in the second region of the active layer forming a first gate stack that surrounds portion of each of the nanowires, forming a second gate stack covering a portion of the fins, and growing an epitaxial material wherein the epitaxial material defines source and drain regions of the nanowire FET and source and drain regions of the finFET.
US08536022B2 Method of growing composite substrate using a relaxed strained layer
A method according to embodiments of the invention includes providing an epitaxial structure comprising a donor layer and a strained layer. The epitaxial structure is treated to cause the strained layer to relax. Relaxation of the strained layer causes an in-plane lattice constant of the donor layer to change.
US08536017B2 Method of manufacturing semiconductor device
A polysilazane film is formed over the main surface of a semiconductor substrate in such a manner that the upper surface level of the polysilazane film buried in a trench of 0.2 μm or less in width becomes higher than that of a pad insulating film and the upper surface level of the polysilazane film buried in a trench of 1.0 μm or more in width becomes lower than that of the pad insulating film. Then, heat treatment is conducted at 300° C. or more to convert the polysilazane film into a first buried film made of silicon oxide (SiO2) and remove a void in the upper portion of the narrower trench.
US08536013B2 Forming phase change memory cells
Small phase change memory cells may be formed by forming a segmented heater over a substrate. A stop layer may be formed over the heater layer and segmented with the heater layer. Then, sidewall spacers may be formed over the segmented heater to define an aperture between the sidewall spacers that may act as a mask for etching the stop layer over the segmented heater. As a result of the etching using the sidewall spacers as a mask, sublithographic pore may be formed over the heater. Phase change material may be formed within the pore.
US08536008B2 Manufacturing method of vertical channel transistor array
A vertical channel transistor array has an active region formed by a plurality of semiconductor pillars. A plurality of embedded bit lines are arranged in parallel in a semiconductor substrate and extended along a column direction. A plurality of bit line contacts are respectively disposed on a side of one of the embedded bit lines. A plurality of embedded word lines are arranged in parallel above the embedded bit lines and extended along a row direction. Besides, the embedded word lines connect the semiconductor pillars in the same row with a gate dielectric layer sandwiched between the embedded word lines and the semiconductor pillars. The current leakage isolation structure is disposed at terminals of the embedded bit lines to prevent current leakage between the adjacent bit line contacts.
US08536007B2 Non-volatile memory cell and logic transistor integration
A first conductive layer and an underlying charge storage layer are patterned to form a control gate in an NVM region. A first dielectric layer is formed over the control gate. A sacrificial layer is formed over the first dielectric layer and planarized. A patterned masking layer is formed over the sacrificial layer which includes a first portion which defines a select gate location laterally adjacent the control gate in the NVM region and a second portion which defines a logic gate in a logic region. Exposed portions of the sacrificial layer are removed such that a first portion remains at the select gate location. A second dielectric layer is formed over the first portion and planarized to expose the first portion. The first portion is removed to result in an opening at the select gate location. A gate dielectric layer and a select gate are formed in the opening.
US08536003B2 Method for fabricating semiconductor power device
A method for fabricating a semiconductor power device includes the following steps. First, a substrate having thereon at least a semiconductor layer and a pad layer is provided. Then, at least a trench is etched into the pad layer and the semiconductor layer followed by depositing a dopant source layer in the trench and on the pad layer. A process is carried out thermally driving in dopants of the dopant source layer into the semiconductor layer. A rapid thermal process is performed to mend defects in the dopant source layer and defects between the dopant source layer and the semiconductor layer. Finally, a polishing process is performed to remove the dopant source layer from a surface of the pad layer.
US08536000B2 Method for producing a semiconductor device have fin-shaped semiconductor regions
First and second gate insulating films are formed so as to cover at least the upper corner of first and second fin-shaped semiconductor regions. The radius of curvature r1′ of the upper corner of the first fin-shaped semiconductor region located outside the first gate insulating film is greater than the radius of curvature r1 of the upper corner of the first fin-shaped semiconductor region located under the first gate insulating film and is less than or equal to 2×r1. The radius of curvature r2′ of the upper corner of the second fin-shaped semiconductor region located outside the second gate insulating film is greater than the radius of curvature r2 of the upper corner of the second fin-shaped semiconductor region located under the second gate insulating film and is less than or equal to 2×r2.
US08535994B2 Thin-film transistor array device manufacturing method
The following processes are included: preparing a substrate; forming a first gate electrode above the substrate; forming a second gate electrode above the substrate and adjacent to the first gate electrode; forming a gate insulating film on the first gate electrode and the second gate electrode; forming, on the gate insulating film, a noncrystalline semiconductor film at least in a first region above the first gate electrode and a second region above the second gate electrode; irradiating the noncrystalline semiconductor film a laser beam having continuous convex light intensity distributions; and forming a first source electrode and a first drain electrode above the first region, and a second source electrode and a second drain electrode above the second region. In the irradiating, when irradiating the first region with an inner region of the laser beam, the second region is irradiated with an outer region of the laser beam.
US08535988B2 Large panel leadframe
A method of manufacturing an integrated circuit package includes mounting a large panel leadframe having a substantially square shape to a ring. The large panel leadframe includes a plurality of die pads and a corresponding plurality of leads arranged in a matrix pattern. An integrated circuit chip is attached to each of the die pads. An encapsulant material is applied over the integrated circuit chips and at least a part of the large panel leadframe. Each of the die pads and its corresponding leads are separated from the large panel leadframe to form individual integrated circuit packages. The steps of attaching the integrated circuit chips and applying the encapsulant material are performed while the large panel leadframe is mounted to a taped ring.
US08535987B2 Method of manufacturing substrate for semiconductor element, and semiconductor device
A manufacturing method of a substrate for a semiconductor element, wherein a first step includes: forming a first and second photosensitive resin layer on a first and second surface of a metal plate, respectively; forming a first and second resist pattern on the first and second surface, for forming a connection post and a wiring pattern, respectively. A second step includes: forming the connection post and wiring pattern; filling in a premold liquid resin to the first surface which was etched; forming a premold resin layer by hardening the premold liquid resin; performing a grinding operation on the first surface, and exposing an upper bottom surface of the connection post from the premold resin layer. A groove structure is formed by the first and second steps, wherein a depth of the groove is up to an intermediate part in a thickness direction of the metal plate.
US08535975B2 Organic light emitting diode display and method for manufacturing the same
An organic light emitting diode (OLED) display and a method for manufacturing the same are provided. The OLED display includes a substrate, an active layer and a capacitor lower electrode positioned on the substrate, a gate insulating layer positioned on the active layer and the capacitor lower electrode, a gate electrode positioned on the gate insulating layer at a location corresponding to the active layer, a capacitor upper electrode positioned on the gate insulating layer at a location corresponding to the capacitor lower electrode, a first electrode positioned to be separated from the gate electrode and the capacitor upper electrode, an interlayer insulating layer positioned on the gate electrode, the capacitor upper electrode, and the first electrode, a source electrode and a drain electrode positioned on the interlayer insulating layer, and a bank layer positioned on the source and drain electrodes.
US08535973B2 Method for producing nanoparticle/block copolymer composites and devices containing the same
A method for producing nanoparticle/block copolymer composites is provided. The method includes mixing nanoparticles having an organic ligand L and a block copolymer A-b-B having block repeating units A and B with different solubility parameters in a solvent S to form micelles by self-assembly. The solubility parameters of the organic ligand L, the block repeating units A and B of the block copolymer A-b-B and the solvent S satisfy the following inequalities: 29≦δS−δA  (1) δS−δB≦29  (2) |δL−δA|≦5 or |δL−δB|≦5  (3) in which δS, δA, δB and δL represent the solubility parameters of the solvent S, the block repeating unit A, the block repeating unit B and the ligand L, respectively. According to the method, the inherent electrical, magnetic, optical, chemical and mechanical properties of the nanoparticles can be maintained or improved without the need to modify the surface of the nanoparticles.
US08535972B2 Methods for coating a substrate with an amphiphilic compound
Methods of modifying a patterned semiconductor substrate are presented including: providing a patterned semiconductor substrate surface including a dielectric region and a conductive region; and applying an amphiphilic surface modifier to the dielectric region to modify the dielectric region. In some embodiments, modifying the dielectric region includes modifying a wetting angle of the dielectric region. In some embodiments, modifying the wetting angle includes making a surface of the dielectric region hydrophilic. In some embodiments, methods further include applying an aqueous solution to the patterned semiconductor substrate surface. In some embodiments, the conductive region is selectively enhanced by the aqueous solution. In some embodiments, methods further include providing the dielectric region formed of a low-k dielectric material. In some embodiments, applying the amphiphilic surface modifier modifies an interaction of the low-k dielectric region with a subsequent process.
US08535971B2 Method for applying full back surface field and silver busbar to solar cell
A method is provided for applying back contact silver busbars to an aluminum back surface field (BSF) of a solar cell. The method involves providing a solar cell substrate having a front side and a back side; printing a full aluminum backing layer on the back side of the solar cell substrate; drying the printed aluminum backing layer to yield a full aluminum layer; printing and drying a peeling paste on the full aluminum layer in areas where the silver busbars are desired; printing and drying a front contact silver paste on the front side of the solar cell substrate to produce a front grid electrode; co-firing and cooling the front and back sides of the solar cell, wherein during firing the peeling paste wets excess aluminum powder in the aluminum layer, such that during cooling of the solar cell the peeling paste contracts, solidifies, and peels off with the excess aluminum powder to leave a full aluminum BSF having open areas; and printing, drying, and firing a back contact silver paste on the open areas of the BSF to yield silver busbars.
US08535965B2 Silicon nitride film, a semiconductor device, a display device and a method for manufacturing a silicon nitride film
The present invention provides a method for forming by plasma CVD a silicon nitride film that can be formed over heat-sensitive elements as well as an electroluminescent element and that has favorable barrier characteristics. Further, the present invention also provides a semiconductor device, a display device and a light-emitting display device formed by using the silicon nitride film. In the method for forming a silicon nitride film by plasma CVD, silane (SiH4), nitrogen (N2) and a rare gas are introduced into a deposition chamber in depositing, and the reaction pressure is within the range from 0.01 Torr to 0.1 Torr.
US08535963B2 Method for manufacturing electronic device and electronic device
A method for manufacturing an electronic device comprises a step for forming a coating film (100) on a surface of a conductor portion-containing body (500), a step for forming a photosensitive film (110) on the conductor (500) on which the coating film (100) has been formed, a step for exposing the photosensitive film (110) to a pattern corresponding to a patterned recessed or protruded portion, a step for developing the exposed photosensitive film (110), and a step for baking the developed photosensitive film (110). With this method, an excessive removal of a metal film can be prevented or suppressed.
US08535957B1 Dopant metrology with information feedforward and feedback
The present invention may include a first dopant metrology system configured to measure a first plurality of values of at least one parameter of a wafer, an ion implanter configured to implant a plurality of ions into the wafer, a second dopant metrology system configured to measure a second plurality of values of at least one parameter of the wafer following ion implantation of the wafer by the implanter, wherein the first dopant metrology system and the second dopant metrology system are communicatively coupled, an annealer configured to anneal the wafer following ion implantation, and a third dopant metrology system configured to measure a third plurality of values of at least one parameter of the wafer following annealing of the wafer by the annealer, wherein the second dopant metrology system and the third dopant metrology system are communicatively coupled.
US08535956B2 Chip attach frame
A chip attach frame is used to align pins of an integrated circuit chip with pads on a chip carrier. A frame block has a socket defining two alignment edges that form a reference corner. The chip is lowered into the socket, and the chip carrier is inclined while it supports the frame block and chip until the chip moves under force of gravity to the reference corner. Once located at the reference corner, the chip position is carefully adjusted by moving the frame block in the x- and y-directions until the pins are aligned with the pads. The frame block is spring biased against movement in the x- and y-directions, and the position of the frame block is adjusted using thumbscrews. A plunger mechanism can be used to secure the integrated circuit chip in forcible engagement with the chip carrier once the pins are aligned with the pads.
US08535954B2 Magnetoresistive random access memory element and fabrication method thereof
A magnetoresistive random access memory (MRAM) element includes a bottom electrode embedded in a first insulating layer; an annular reference layer in a first via hole of a second insulating layer on the first insulating layer, the annular reference layer being situated above the bottom electrode; a first gap fill material layer filling the first via hole; a barrier layer covering the annular reference layer, the second insulating layer and the first gap fill material layer; an annular free layer in a second via hole of a third insulating layer on the second insulating layer, the annular free layer being situated above the annular reference layer; and a top electrode stacked on the annular free layer.
US08535952B2 Method for manufacturing non-volatile magnetic memory
In accordance with a method of the present invention, a method of manufacturing a magnetic random access memory (MRAM) cell and a corresponding structure thereof are disclosed to include a multi-stage manufacturing process. The multi-stage manufacturing process includes performing a front end on-line (FEOL) stage to manufacture logic and non-magnetic portions of the memory cell by forming an intermediate interlayer dielectric (ILD) layer, forming intermediate metal pillars embedded in the intermediate ILD layer, depositing a conductive metal cap on top of the intermediate ILD layer and the metal pillars, performing magnetic fabrication stage to make a magnetic material portion of the memory cell being manufactured, and performing back end on-line (BEOL) stage to make metal and contacts of the memory cell being manufactured.
US08535949B2 Water relaxation-based sensors
This invention relates to magnetic resonance-based sensors and related methods.
US08535947B2 On-line monitoring of deprotection reaction in peptide automated synthesizer comprising UV detector
A method for on-line monitoring of deprotection reaction in a peptide automated synthesizer comprising UV detector is disclosed. A UV source, detector, electronics, and housing are integrated with a line or tube through which liquid reactants flow for periodic measurements in the peptide synthesizer. The method includes determining the progression of the reaction, completion point of the reaction, and the modification of the reaction times and repetitions in real time.
US08535943B2 Blood platelet induction method
A novel induction method that effectively produces platelets from platelet precursor cells (e.g., hemopoietic stem/precursor cells) is disclosed. The method includes culturing platelet precursor cells in a culture solution in which a composite membrane is immersed so that the platelet precursor cells differentiate into platelets, the composite membrane including a porous support membrane and a porous thin membrane, the porous thin membrane being stacked on at least one side of the porous support membrane.
US08535942B2 Glypican-3 (GPC3)-derived tumor rejection antigenic peptides useful for HLA-A2-positive patients and pharmaceutical comprising the same
It is an object of the present invention to identify a glypican-3-derived peptide which can bind to HLA-A2 and activate human killer T cells, so as to provide a means for carrying out an immunotherapy which is able to target approximately 40% of Japanese patients suffering from several types of cancers, which express GPC3 at a high level. The present invention provides a peptide of any of the following (A) or (B): (A) a peptide, which has the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3; or (B) a peptide, which has an amino acid sequence comprising a substitution or addition of one or two amino acids with respect to the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3, and which has ability to induce killer T cells.
US08535941B2 Lipophilic dye-based FRET assays for clostridial toxin activity
Compositions useful for detecting Clostridial toxin activity comprising a cell that comprises a membrane-associated Clostridial toxin substrate comprising a first member of a fluorescence resonance energy transfer pair; and a Clostridial toxin recognition sequence including a cleavage site; and a membrane-associated second member of the FRET pair and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates.
US08535932B2 Lecanicillium muscarium strain V-5, pest extermination method using the same, and microorganism pesticide comprising the same
A microbial pesticide which is safe for the environment, fast-acting and excellent in an insecticidal effect in case of spray treatment for eggs and larvae of a pest is required. The invention provides a method for controlling at least one pest selected from the group consisting of whiteflies, aphid, spider mites, thrips, rust mites, leaf miners, pyralidae, cabbage moths and longhorn beetles, with Lecanicillium muscarium strain V-5 (deposition number: FERM BP-11135); and a microbial pesticide comprising the strain.
US08535931B2 Non-photosynthetic micro-organisms enriched with organic selenium from seleno-hydroxyacid compounds and applications thereof in the field of nutrition, cosmetics and pharmacueuticals
The invention relates to the enrichment of non-photosynthetic micro-organisms with organic selenium, and more particularly with selenomethionine, from a compound of the seleno-hydroxyacid type such as 2-hydroxy-4-methylseleno-butanoic acid in the (D, L) form or in the form of an enantiomer, salt, ester, or amide derivative of said compound, and to the use of micro-organisms, particularly bacteria thus enriched in the fields of animal or human nutrition, cosmetics, or pharmaceuticals.
US08535926B2 Cellulases with high activities
Two novel cellulases and nucleotide sequences encoding the same are disclosed. Also disclosed are compositions and methods for using the same for hydrolyzing cellulosic waste materials.
US08535919B2 Process for converting gas stream comprising CO, CO2 and H2 to liquid products by fermentation
A process converts a gas input stream comprising CO, CO2, and H2 by contact with fermentation liquid into a liquid product that controls the concentration of CO and CO2 in the fermentation vessel. The process charges the feed gas stream and a recycle gas stream to the fermentation vessel and an off-gas stream collects above the fermentation liquid. The off-gas stream flows to a gas injector that uses a recycle liquid as the motive fluid to mix the off-gas with the recycle liquid into a gas-liquid dispersion. Contact of the recycle liquid with the off-gas absorbs CO2 to provide the recycle stream. A gas separation vessel separates the remainder of the off-gas into the recycle gas. Mixing the recycle gas with the gas input stream dilutes the concentration of CO to lower the CO concentration in the fermentation vessel. Separated recycle liquid flows to a CO2 stripper for removal of CO2.
US08535914B2 Probe, probe set and information acquisition method using the same
The present invention provides a combination of genes useful for information which can be used for the prediction of postoperative recurrence of gastric cancer and the acquisition of the information, a probe detecting these genes and a primer set for PCR, a method for detecting these genes using the primer and the primer set and a method for obtaining the information which can be used for the prediction of recurrence. Information useful for the prediction of postoperative recurrence can be obtained by determining the presence or absence of gastric cancer cells which show a possibility of postoperative recurrence in a sample such as an peritoneal wash collected from a patient by detecting a particular gene specific to gastric cancer cells or a gene product thereof.
US08535907B2 Protein concentrates and isolates, and processes for the production thereof from toasted oilseed meal
Protein concentrates and protein isolates, in addition to processes for the production of protein concentrates and protein isolates, are disclosed. In particular, the disclosure relates to the removal of fiber from a toasted oilseed meal using low g-force centrifugation.
US08535905B2 Method for isolating a part of a layer of biological material
A film (14) with a tissue section (10) is placed with the tissue section (10) downward on a microscope slide (18) and the microscope slide (18) positioned in the object plane of an inverse microscope; where an adhesive tape (20) is arranged, with a bonding agent (22) downward, above the film (14) and therefore above the tissue section (10); wherein the next step, tissue (36) to be isolated is excised by a focused laser beam, which also divides the film (14); whereupon removal of the adhesive tape (20) from the microscope, the excised tissue pieces (36) adhere to the adhesive tape (20), and the remnant of the film (14) and of the tissue section (10) remains adhering/to the microscope slide (18).
US08535903B2 Nitroreductase enzymatic substrates
The invention relates to the use of a compound having formula (I) as an enzymatic substrate for the detection of a nitroreductase activity or as an enzymatic substrate for the detection of a nitroreductase activity and indicator of pH, wherein: W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination of same; n=0, 1 or 2; U and V are N, N+R, CZ4, R being H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonic, preferably if U is CZ4, V is N or N+R and, if V is CZ4, U is N or N+R; and Z1, Z2, Z3 and Z4 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the sulphonyl or carboxyl amides or esters thereof, and the salts of same.
US08535896B2 Biomarkers for inflammation of the liver
The invention relates to a method for the diagnostic investigation of biological samples from a person for inflammation of the liver, in particular hepatic fibrosis and/or cirrhosis of the liver, where the sample is investigated for one or more proteins as markers of inflammation of the liver, in particular hepatic fibrosis and/or cirrhosis of the liver, where a concentration of the proteins which is elevated or decreased by comparison with the healthy state indicates the presence of an inflammation of the liver, in particular a hepatic fibrosis and/or cirrhosis of the liver. The proteins are selected from the group of ER6Q, vimentin, actin alpha 1 skeletal muscle protein, hMFAP 4, tropomyosin, PTGES 2, amyloid P component, transgelin, calponin 1, homo sapiens p20 protein, 17 kDa myosin light chain, H chain H Igg B12, prolyl 4-hydroxylase, beta subunit methylenetetrahydrofolate dehydrogenase 1, PRO2619, aldehyde dehydrogenase 1, fibrinogen alpha chain preproprotein, fructose-bisphosphate aldolase B, argininosuccinate synthetase, Eefla2, AT P 5 A1, alpha-2 actin, regucalcin, serum albumin, mitochondrial malate dehydrogenase, mitochondrial acetoacetyl-CoA thiolase or in each case a partial sequence thereof.
US08535895B2 Highly sensitive system and method for analysis of troponin
The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin. Such methods, compositions, kits, and systems are useful in diagnosis, prognosis, and determination of methods of treatment in conditions that involve release of cardiac troponin.
US08535894B2 Antibody complexes and methods for immunolabeling
Provided are labeling reagents and methods for labeling primary antibodies and for detecting a target in a sample using an immuno-labeled complex that comprises a target-binding antibody and one or more labeling reagents. The labeling reagents comprise monovalent antibody fragments or non-antibody monomeric proteins whereby the labeling proteins have affinity for a specific region of the target-binding antibody and are covalently attached to a label. Discrete subsets of labeling reagent and immune-labeled complexes are provided that facilitate the simultaneous detection of multiple targets in a sample-complexes are distinguished by i) a ratio of label to labeling reagent, or ii) a physical property of said label, or iii) a ratio of labeling reagent to said target-binding antibody, or iv) by said target-binding antibody. This is particularly useful for fluorophore labels that can be attached to labeling reagents and subsequently immuno-labeled complexes in ratios for the detection of multiple targets.
US08535893B2 Resistance to auxinic herbicides
The invention provides methods of identifying herbicidal auxins. The invention further provides auxin-herbicide-resistant plants and genes conferring auxin-herbicide resistance. This invention also provides a method of identifying other proteins that bind picolinate auxins from additional plant species. The invention further provides a method to identify the molecular binding site for picolinate auxins. The invention also includes the use of the picolinate herbicidal auxin target site proteins, and methods of discovering new compounds with herbicidal or plant growth regulatory activity. The invention also includes methods for producing plants that are resistant to picolinate herbicidal auxins. Specific examples of novel proteins associated with herbicide binding include AFB5, AFB4, and SGT1b.
US08535891B2 Method of predicting acute appendicitis
Embodiments of the invention provide method and devices for predicting the likelihood of acute appendicitis without invasive exploratory medical procedures. Several protein biomarkers: leucine-rich α-2-glycoprotein (LRG); S100-A8 (calgranulin); α-1-acid glycoprotein 1 (ORM); plasminogen (PLG); mannan-binding lectin serine protease 2 (MASP2); zinc-α-2-glycoprotein (AZGP1); Apolipoprotein D (ApoD); and α-1-antichymotrypsin (SERPINA3); are increased in the urine of patients with appendicitis. The method and devices comprise detecting the levels of these biomarkers and comparing with reference levels found in healthy individuals.
US08535890B2 Methods to determine immunogenicity of humanized anti-tag 72 CC49 antibodies
The present disclosure provides humanized CC49 monoclonal antibodies that bind TAG-72 with high binding affinity and that are minimally immunogenic. In one embodiment, a humanized CC49 antibody includes a non-conservative amino acid substitution in a light chain complementarity determining region 3 of the CC49 antibody. In a further embodiment, the humanized CC49 antibody includes a non-conservative substitution of a first residue in a light chain complementarity determining region 3 and a substitution of a second residue in a complementarity determining region of the humanized CC49 antibody. In several of the embodiments, methods are disclosed for the use of a humanized CC49 antibody.
US08535888B2 Compositions and methods for detecting methicillin-resistant S. aureus
The present invention relates to methods of detecting the presence or absence of methicillin-resistant S. aureus (MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.
US08535884B2 LMNA gene and its involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and arteriosclerosis
Disclosed herein are point mutations in the LMNA gene that cause HGPS. These mutations activate a cryptic splice site within the LMNA gene, which leads to deletion of part of exon 11 and generation of a mutant Lamin A protein product that is 50 amino acids shorter than the normal protein. In addition to the novel Lamin A variant protein and nucleic acids encoding this variant, methods of using these molecules in detecting biological conditions associated with a LMNA mutation in a subject (e.g., HGPS, arteriosclerosis, and other age-related diseases), are also described. Oligonucleotides and other compounds for use in examples of the described methods are also provided, as are protein-specific binding agents, such as antibodies, that bind specifically to at least one epitope of a Lamin A variant protein preferentially compared to wildtype Lamin A, and methods of using such antibodies in diagnosis, treatment, and screening.
US08535880B2 Organ-specific gene, method for identifying the same and use thereof
The present invention provides a method of extracting an organ- or tissue-specific highly expressed gene, including: (1) a step for measuring expression level of a specified gene group for each organ or tissue in 2 or more individuals, (2) a step for acquiring (a) a minimum value of expression levels in a particular organ or tissue in all individuals, and (b) a maximum value of expression levels in other organs and tissues in all individuals, for each gene, and (3) a step for extracting the gene as a gene highly expressed specifically in the particular organ or tissue if the above-described (a)/(b) ratio is larger than 1. By the present invention, truly organ- or tissue-specific genes are extracted.
US08535876B2 Laser-micro-dissection method and device for laser-micro-dissection
A laser-micro-dissection method and a device for laser micro-dissection involves cutting a dissectate from a biological sample, which is applied to a planar carrier, by means of laser pulses along a closed cutting line. The parameters, which determine the laser pulses and the cut lines, are synchronous in relation to the laser pulses and are continually modified along the closed cut line. All elements which are arranged in the optical axis and which determine the parameters of the laser pulse and the cut lines, are controlled by a central calculation unit.
US08535874B2 Fluorene-based polymer containing urethane groups, preparation method thereof and negative-type photosensitive resin composition comprising the same
Provided is a novel fluorene-based polymer having urethane bonds and a method for preparing the fluorene-based polymer. According to the method, a diol compound is condensed with a diisocyanate instead of an acid dianhydride, and then an acid anhydride is reacted with the reaction mixture to introduce desired acid groups into the final polymer. Further provided is a negative-type photosensitive resin composition comprising of the fluorene-based polymer as a binder resin. The composition exhibits improved chemical resistance, good development margin and high sensitivity due to presence of the acid groups despite the low molecular weight of the fluorene-based polymer.
US08535873B2 Photosensitive resin composition
Disclosed is a photosensitive resin composition which has excellent transparency, heat resistance, thermal discoloration resistance, adhesion to a substrate and electrical characteristics, while exhibiting good developability and storage stability. Specifically disclosed is a photosensitive resin composition which contains the following components (A), (B) and (C). (A) a copolymer which contains (a1) hydroxyphenyl (meth)acrylate and (a2) an unsaturated epoxy compound as copolymerization components (B) a novolac resin which contains one or more phenols selected from among dimethylphenol, trimethylphenol, methylpropylphenol, dipropylphenol, butylphenol, methylbutylphenol, dibutylphenol, and 4,4′-dihydroxy-2,2′-diphenylpropane (C) a quinonediazide group-containing compound.
US08535870B2 Organic pigments for colour filters
Use of pigments of the formula (I) containing melamine as guest compound and having a dispersion harshness of more than 250 as pigments for color filters for liquid-crystal displays.
US08535869B2 Sulfonium salt, resist composition, and patterning process
A sulfonium salt of a naphthylsulfonium cation having a hydrophilic phenolic hydroxyl group or ethylene glycol chain with a specific anion is provided. The sulfonium salt is used as a photoacid generator to form a resist composition which when processed by immersion lithography, offers advantages of restrained dissolution in the immersion water and less pattern dependence or dark-bright difference.
US08535859B2 Photoconductors containing biaryl polycarbonate charge transport layers
A photoconductor that includes a supporting substrate, an optional ground plane layer, an optional hole blocking layer, an optional adhesive layer, a photogenerating layer, and at least one charge transport layer, and where the charge transport layer contains a biaryl polycarbonate, or a mixture of a biaryl polycarbonate and a second polymer such as a polycarbonate.
US08535855B2 Mask blank manufacturing method, transfer mask manufacturing method, mask blank, and transfer mask
Provided is a method of manufacturing a mask blank having a thin film on a transparent substrate. The method includes forming the thin film made of a material containing a transition metal on the transparent substrate and applying a superheated steam treatment to the thin film.
US08535848B2 Structured body for an anode used in fuel cells
The structured body intended for use for an anode (1) in fuel cells, includes a structure formed by macro-pores and an electrode material. The macro-pores form communicating spaces which are produced by using pore forming materials. The electrode material includes skeleton-like or net-like connected structures of particles which are connected by sintering and which form two reticular systems which interengage: a first reticular system made of ceramic material and a second reticular system which contains metals to effect an electrical conductivity. The electrode material has the properties so that, with a multiple change between oxidizing and reducing conditions, substantially no major property changes occur in the ceramic reticular system, and an oxidization or reduction of the metals occurs in the second reticular system.
US08535847B2 Membrane/electrode assembly for polymer electrolyte fuel cell
A membrane electrode assembly less susceptible to flooding or shortcircuiting caused by piercing of carbon fibers of a gas diffusion layer to a polymer electrolyte membrane is provided, containing a cathode having a catalyst layer and a gas diffusion layer, an anode having a catalyst layer and a gas diffusion layer, and a polymer electrolyte membrane interposed between the catalyst layer of the cathode and the catalyst layer of the anode, wherein each of the cathode and the anode further has a protective layer containing carbon fibers having an average fiber diameter of from 1 to 30 μm and a fluorinated ion exchange resin, between the catalyst layer and the gas diffusion layer, and the mass ratio (F/C) of the fluorinated ion exchange resin (F) to the carbon fibers (C) contained in the protective layer is from 0.05 to 0.30.
US08535846B2 Fuel cell
A fuel cell includes a stack structure composed of fuel cell units with current collectors between the fuel cell units, a casing housing the stack structure, and a gas flow-regulating member provided in a gap between the casing and the stack structure. The fuel cell unit includes: a cell plate which holds at least one cell and has a gas introduction hole for one of fuel gas and air; and a separator plate which has a gas introduction hole for the one of the fuel gas and the air. The casing introduces the other of the fuel gas and the air via a gas introduction portion and flows the other gas to a gas discharge portion. The gas flow-regulating member guides the other gas to the gas discharge portion through the current collectors.
US08535839B2 Fuel cell system containing anode tail gas oxidizer and hybrid heat exchanger/reformer
A fuel cell system includes at least one fuel cell stack, a fuel inlet conduit, and a fuel heat exchanger containing a fuel reformation catalyst. The fuel heat exchanger is connected to the fuel inlet conduit and to at least one fuel cell system exhaust conduit which in operation provides a high temperature exhaust stream to the fuel heat exchanger. The fuel heat exchanger is thermally integrated with an anode tail gas oxidizer (ATO) exhaust conduit such that in operation an ATO exhaust stream in the ATO exhaust conduit heats a fuel inlet stream passing through the heat exchanger.
US08535837B2 Fuel cell system
There are included a gas-liquid separator (14) that performs gas-liquid separation on fuel exhaust gas exhausted from a fuel cell (11), a combustion section (13) that combusts hydrogen in the separated fuel exhaust gas, a heat exchanger (15) that performs heat exchange on combustion exhaust gas generated by the combustion, to condense moisture in the combustion exhaust gas and obtain combustion exhaust gas condensed water, and a degasifier (16) that removes carbon dioxide gas from the combustion exhaust gas condensed water and the fuel exhaust gas condensed water separated in the gas-liquid separator (14), and the degassed condensed water is stored in condensed water tank (18).
US08535835B2 Fuel battery module and fuel battery device
A fuel cell module that can accommodate a single fuel cell stack efficiently and that can enhance power generation efficiency, and a fuel cell device comprising the fuel cell module.
US08535833B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same
A non-aqueous electrolyte solution for a lithium secondary battery comprises a lithium salt and an organic solvent. The non-aqueous electrolyte solution further comprises a specific siloxane compound and a sulfonate compound. This non-aqueous electrolyte solution solves the capacity degradation phenomenon, which appears in a lithium secondary battery using a non-aqueous electrolyte solution containing only a specific siloxane compound when the lithium secondary battery is used for a long time, so this non-aqueous electrolyte solution is especially useful for high-capacity batteries.
US08535829B2 Lithium transition metal-based compound powder for positive electrode material in lithium rechargeable battery, method for manufacturing the powder, spray dried product of the powder, firing precursor of the powder, and positive electrode for lithium rechargeable battery and lithium rechargeable battery using the powder
There is provided a powder of a lithium transition-metal compound for a positive-electrode material in a lithium secondary battery, in which the use of the powder as that of a positive-electrode material in a lithium secondary battery achieves a good balance among improvement in battery performance, cost reduction, resistance to a higher voltage, and a higher level of safety. The powder of the lithium transition-metal compound for a positive-electrode material in a lithium secondary battery is characterized in that in a mercury intrusion curve obtained by mercury intrusion porosimetry, the amount of mercury intruded is in the range of 0.8 cm3/g to 3 cm3/g when the pressure is increased from 3.86 kPa to 413 MPa.
US08535828B2 Rechargeable battery
A rechargeable battery includes: an electrode group including a positive electrode, a negative electrode, and a separator interposed between the positive electrode and the negative electrode; a case housing the electrode group; a cap-up electrically connected with the electrode group and combined with the case; a vent plate installed below the cap-up and having a notch; and a heterogeneous metallic member installed between the cap-up and the vent plate and made of a clad metal, whereby the stability and outputting of the rechargeable battery can be improved.
US08535825B2 Mandrel with drive member for electrochemical cells
A mandrel for an electrochemical cell includes an elongated hollow tube. At least one drive member is provided at an end of the hollow tube and is configured to receive a driver in order to rotate the mandrel. The drive member is configured to electrically insulate the hollow tube from an electrode that is wound around the hollow tube.
US08535820B2 Battery module
A battery module including a plurality of battery cells arranged in a direction, and a plurality of barriers, each arranged between battery cells of the plurality of battery cells and including a body unit having at least one opening and facing a face of a battery cell of the battery cells, at least one side unit connected to at least one end of the body unit such that at least a portion of the at least one side unit contacts a side of the battery cell, and at least one fixing unit on the side unit and configured to connect the barrier to an adjacent barrier of the plurality of barriers.
US08535814B2 Heterocyclic compound and organic light emitting device including the same
Embodiments of the present invention are directed to heterocyclic compound and an organic light-emitting device including the heterocyclic compound. The heterocyclic compound is represented by Formula 1.Formula 1
US08535813B2 Use of a metal composite material in a vehicle structure
A use of a coilable multi-layer metallic composite material produced by means of roll-cladding in a vehicle structure, in particular a body structure, provides an alternative to monolithic materials. The composite material used in a vehicle structure is a lightweight composite material and comprises three layers of a steel alloy, wherein at least one of the layers is formed from a high-strength or very high-strength steel alloy.
US08535811B2 Transparent molding composition
A polyamide molding composition which can be used for production of a printable or printed item contains a) at most 90 parts by weight of a polyamide obtained from a lactam or from an amino carboxylic acid having at least 10 carbon atoms; and b) from 10 to 100 parts by weight of PA1010, wherein a total of components a) and b) is 100 parts by weight.
US08535810B2 Transparent plastic film for shielding electromagnetic waves and method for producing a plastic film of this type
A transparent plastic film for screening electromagnetic waves includes a transparent film substrate and a layer system comprising at least one silver layer and two niobium oxide layers. The silver layer is embedded between the two niobium oxide layers.
US08535808B2 Heat dissipation coating agent and heat-dissipating plate including same
The present invention relates to a heat dissipation coating agent and to a heat-dissipating plate including same, which efficiently dissipate heat from the surface of a heat-dissipating plate of an electric/electronic component. Particularly, the heat dissipation coating agent, which is applied to the surface of a heat-dissipating plate of an electric/electronic component, includes infrared radiation powder and a binder, and the heat-dissipating plate is coated with a heat dissipation layer consisting of the heat dissipation coating agent. Since the heat dissipation coating agent applied to the heat-dissipating plate is highly conductive, heat is emitted from the heat-dissipating plate by conduction as well as convection. In particular, the heat dissipation coating agent, which conducts heat with high conductivity, can be applied to a heat-dissipating plate of a high-power LED light source.
US08535806B2 Medical device having bonding regions and method of making the same
Medical devices having bonded joints are disclosed. The bonded joints include two surfaces bonded by a layer of phenoxy resin therebetween. In the preferred embodiments, bonded surfaces include materials that are suitable for medical devices. Most preferably, Nitinol includes at least one bonded surface, however, other preferred materials may include, but are not limited to cobalt chromium, stainless steel, titanium, tantalum, and plastic. An intraluminal device including a plurality of locations with a phenoxy resin layer is also disclosed wherein the phenoxy resin further includes a radioopaque additive, a lubricious additive, or both radioopaque and lubricious additives. Also disclosed is an intraluminal device having contiguous heterogeneous structural elements of metallic members and non-metallic sections that are bonded together by a layer of phenoxy resin therebetween.
US08535794B2 Device, especially sporting equipment for use in surfing or similar activities, and a method for producing fiber composites
Device, especially a piece of sporting equipment for use in surfing or similar activities, includes a base made of foamed plastic, which has at least one laminate coating made of a fabric laminate and an underlay compound. The device includes an intermediate layer between the base and the laminate coating. Likewise provided are a number of processes for producing fiber composites in connection with foamed plastics.
US08535791B2 Aligned carbon nanotube-polymer materials, systems and methods
Aligned carbon nanotube-polymer composite materials, systems and methods include a substrate that carries an adhesive coating thereon. A plurality of carbon nanostructures are adhered to the substrate by the adhesive coating, such that the nanostructures are formed into a predetermined architecture, such that the architecture of the nanostructures defines at least one orientation for a plurality of nanostructures, and defies the approximate spacing between the nanostructures and/or groups of nanostructures. The adherence of the carbon nanostructures in the adhesive coating stabilizes the predetermined architecture of the nanostructures, such that the architecture renders the composite material superhydrophobic.
US08535787B1 Heat sinks having a thermal interface for cooling electronic devices
Heat sinks having a thermal interface for cooling electronic devices processing units are described herein. In some embodiments, a thermal interface member includes a first material defining a first layer of the apparatus. The thermal interface member further includes a second material being deformable and thermally conductive, and a third material different from the second material, that is an adhesive material. The second material and the third material collectively define a second layer of the apparatus having a first region and a second region. The first region is formed from the second material. The second region is formed from the third material.
US08535786B2 Web and adhesive strip
Represented and described is a sheet having at least one fastening section for the bonding of the sheet to a substrate or for bonding to a further sheet. In accordance with the invention the fastening section is coated partially with an adhesive and has at least two bonding regions formed by the adhesive coating, and adjacent bonding regions are separated from one another at least partly by at least one adhesive-free region of the fastening section.
US08535784B2 Contoured composite parts
One embodiment of a composite part comprises a curved elongated section comprising a plurality of stacked reinforcement layers. The stacked reinforcement layers in the curved elongated section comprise at least one of non-continuous woven fabric and non-continuous reinforcement.
US08535780B2 Coreless tissue rolls and method of making the same
Coreless tissue rolls can be produced without having to use an adhesive to form a hollow center. Instead, moisture can be used to promote light hydrogen bonding between the layers of the tissue web that line the hollow center. The hydrogen bonding provides sufficient structure to maintain the shape of the hollow center without rendering the tissue web surrounding the passageway unusable. Passageways can also be formed in accordance with the present disclosure that are substantially circular so that the rolls will easily spin on a spindle. In an alternative embodiment, moisture is not used in constructing the wound tissue roll.
US08535768B2 Liquid crystal composition and liquid crystal display device
Described is a liquid crystal composition which satisfies at least one of such characteristics as high upper limit temperature of the nematic phase, low lower limit temperature of the nematic phase, low viscosity, adequate optical anisotropy, large negative dielectric anisotropy, high resistivity, high stability to ultraviolet light and high stability to heat, or which has an adequate balance between at least two of the above-mentioned characteristics. Also described is an AM element having a short response time, high voltage holding ratio, high contrast ratio, long life and the like. The liquid crystal composition contains a specific compound having a large negative dielectric anisotropy and a low lower limit temperature as a first component, a specific compound having a low viscosity or a high upper limit temperature as a second component, and a specific compound having a polymerizable group as a third component. The AM element contains the composition.
US08535766B2 Patterning of magnetic thin film using energized ions
A method for patterning a magnetic thin film on a substrate includes: providing a pattern about the magnetic thin film, with selective regions of the pattern permitting penetration of energized ions of one or more elements. Energized ions are generated with sufficient energy to penetrate selective regions and a portion of the magnetic thin film adjacent the selective regions. The substrate is placed to receive the energized ions. The portions of the magnetic thin film are rendered to exhibit a magnetic property different than selective other portions. A method for patterning a magnetic media with a magnetic thin film on both sides of the media is also disclosed.
US08535764B2 Protective coating for concrete delivery system components
The present invention relates to a component of a concrete delivery system comprising a substrate made of relatively thin gauge carbon steel or aluminum, and a protective coating of amorphous, nano or near-nanoscale steel, or mixtures thereof, overlying the substrate, wherein the coating may be formed by thermal deposition process from multi-component glass forming steel alloys. The protective coating may also be heat treated to increase wear life.
US08535761B2 Silsesquioxane derived hard, hydrophobic and thermally stable thin films and coatings for tailorable protective and multi-structured surfaces and interfaces
A method of forming a coating comprising the steps of dissolving an silsesquioxane (e.g., one that is primarily a cage compound with 8, 10, 12, 14 or related complete cages or with partially condensed cages containing primarily Si(O)4 units in the cage) in a solvent to form an silsesquioxane solution; introducing (e.g., dissolving) an additive in the solution (e.g., the additive being selected from a rare earth compound, an acid, an organic moiety, a precious metal or compound thereof, a transition metal compound, or any combination thereof, or any of their ionic constituents); and optionally mixing a diluent with the solution to form a coating that is applied to a substrate, wherein the resulting coating forms crosslinks between resulting pendant Si(OH)x groups and a substrate surface. The present invention also contemplates coatings and coated articles consistent with the present teachings.
US08535756B2 Method for dispensing random pattern of adhesive filaments
A nozzle for dispensing a random pattern of liquid adhesive filaments. The nozzle may include first and second air shim plates, an adhesive shim plate and first and second separating shim plates. The first and second air shim plates each have respective pairs of air slots. Each air slot has a process air inlet and a process air outlet and the air slots of each pair converge toward one another such that the process air inlets are farther apart than the process air outlets in each pair. The adhesive shim plate includes a plurality of liquid slots each with a liquid outlet. Four process air outlets are associated with each of the liquid outlets. The process air slots are adapted to receive pressurized process air and the liquid slots are adapted to receive pressurized liquid adhesive.
US08535755B2 Corrosion resistant riser tensioners, and methods for making
A method for making a riser tensioner component is provided. The method comprises the steps of (a) applying a cold spray composition to a metal substrate to achieve a first coating on the metal substrate, wherein the cold spray composition comprises a metal alloy, and wherein the first coating has a thickness in a range from about 5 to about 50 mils; and (b) rough finishing the first coating to achieve a second coating having an average roughness, Ra of less than about 32 micro-inches. A riser tensioner component is also provided, wherein the riser tensioner component comprises a cold spray applied coating on a metal substrate, wherein the coating comprises a metal alloy, and wherein the coating has a thickness in a range from about 5 to about 50 mils; and an average roughness, Ra of less than about 32 micro-inches.
US08535754B2 Method of processing a treadmill belt and an apparatus for practicing the method
A method for enhancing anti-abrasion of a belt of a treadmill and an apparatus for practicing the method are disclosed herein. As processing the belt, the belt is installed in the apparatus and a driving device of the apparatus can move the belt. A distributing device of the apparatus scatters solid lubricative material on the surface of the belt. As the belt being moved, the lubricative material is melted by a heating device of the apparatus. When the belt is moved to leave the heating device, the melted lubricative material coagulates and engages with the surface of the belt.
US08535752B2 Automated powder-coating method
An automated powder-coating system and method is provided. A series of conveyor belts are arranged end to end to transition one or more work pieces between the conveyor belts. Sensors are used to determine the current location of a work piece with respect to the series of conveyor belts. An induction heating coil for preheating work pieces and a powder-coating apparatus for powder coating work pieces are located adjacent to the conveyor belts. A control unit independently starts and stops the individual conveyor belts based on the current location of the work piece. A cooling area may also be included in the powder-coating system. The powder-coating system and method may be used to powder coat varying lengths of work pieces.
US08535751B2 Method for coating an object
A method for coating an object (1). The object (1) is positioned in contact with holding means and the coating (4) is applied in such a way that contact parts (3, 8, 10) of the holding means form part of the coating (4). Contact parts (3, 8, 10) are made from a material having corrosion properties being substantially identical to the corrosion properties of the coating material, preferably from the same material. Thereby the contact parts (3) can form a natural part of the resulting coating (4). The contact parts (3, 8, 10) may subsequently be detached from the holding means and remain attached to the object (1) as part of the coating (4). Provides a substantially full coating (4) to the object (1) in one coating step. Avoids or reduces problems relating to pinholes in coatings. Further an object (1) having a coating (4) which has been provided using the method.
US08535749B2 Oil-and-fat composition, process for production of the composition, chocolate, and process for production of the chocolate
Disclosed is an oil-and-fat composition suitable for the coating with a tempered chocolate, particularly suitable for the enrobing with the chocolate. Also disclosed is a low-fat tempered chocolate suitable for coating, particularly enrobing. Specifically disclosed is an oil-and-fat composition which has a content of an oleoyldipalmitin (P2O) component of 70 to 85% by mass, which contains a symmetric triglyceride 1,3-dipalmitoyl-2-oleoylglycerin (POP) in the oleoyldipalmitin (P2O) component at a ratio of the amount of 1,3-dipalmitoyl-2-oleoylglycerin (POP) to the amount of the oleoyldipalmitin (P2O) component [(POP)/(P2O)] of 0.95 or more by mass, and which has a content of tripalmitin (PPP) of 2 to 6% by mass. The oil-and-fat composition is added to a tempered chocolate.
US08535748B2 Beverages with enhanced flavors and aromas
The present embodiments generally relate to beverages with enhanced flavors and aromas and method of making same. Some embodiments of the present disclosure are directed to soluble coffee and methods of making soluble coffee with improvements in such qualities as taste and aroma.
US08535746B2 Beverage products having steviol glycosides and at least one acid
Beverage compositions including a sweetening amount of Rebaudioside D and an acidulant. The beverage has a titratable acidity of about 9 to about 11.
US08535743B2 Capsule, system and method for preparing a predetermined quantity of beverage suitable for consumption
A capsule, system and method are usable for preparing a predetermined quantity of beverage using an extractable product. The system includes a capsule comprising a cup having a circumferential wall, a bottom at a first end, and a flange-like rim at a second end. The capsule further includes a lid, in use, connected to the flange-like rim. The wall, bottom and lid, in use, enclose an inner space comprising the extractable product. The cup further includes a plurality of substantially concentric circumferential ridges extending outwardly of the cup, wherein the ridges are made of the same material as the cup. The system further includes a beverage brewing device comprising an enclosing member for enclosing the capsule. In use, at least one of the ridges abuts against at least a portion of the enclosing member, such that a sealing engagement between the capsule and the enclosing member is formed.
US08535742B2 Method for processing of fish egg and processed fish egg produced by the method
Provided are a method of processing fish eggs, which can produce fish eggs having a good color tone without using a color-developing agent such as a nitrite or by using a reduced amount of the color-developing agent, and processed fish eggs produced by the method. A lactic acid bacterium, which can improve the color tone of the fish eggs, is added to the fish eggs. The lactic acid bacterium is preferably a lactic acid bacterium belonging to the genus Lactobacillus or Carnobacterium, more preferably Lactobacillus coryniformis K12 (Deposition Number: FERM BP-10945) or Carnobacterium maltaromaticum B64 (Deposition Number: FERM BP-10449).
US08535741B2 Method and composition for administering bioactive compounds derived from Morinda citrifolia
This invention relates to a method and composition for providing in various health benefits by administering various bioactive compounds derived from the plant Morinda cirtrifolia to individuals. This invention relates to using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf More particularly this invention relates to administering one or more of the following: Pyro-phorbide a, Pheophorbide a, Purpin 7, and/or Pheophorbide all which may be derived from Noni leaf extract, Noni leaf juice, and/or Roast leaf Moreover, the foregoing formulations result in alleviating pain and inflammation.
US08535739B2 Sparkle essence system
A plant-based cleaning agent for household use designed to produce optimal cleaning results. This product is comprised of pigeon pea extract and distilled water. To create the proper mixture, 12 g of pigeon pea leaves may be cut up and placed in a beaker, wherein the pigeon pea leaves homogenize with 2000 ml of distilled water. The mixture is centrifuged at 8,000 rpm for ten minutes. The pellet is then discarded and the extract is stored at approximately 4 degrees C. for about forty-eight hours. Stability is achieved by putting the extract through a 0.45 um filter. For use, consumers spray the sparkle essence product onto a desired glass surface and wipe away with a cloth or paper towel.
US08535735B2 Identification of free-B-ring flavonoids as potent COX-2 inhibitors
The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.
US08535732B2 NGNA compositions and methods of use
The present invention relates to the field of viral disorders, and in particular to viral obesity. Compositions comprising nutraceutical agents are provided for treating viral obesity. Additionally, compositions comprising nutraceutical agents targeting adenoviruses are provided.
US08535730B1 Anticalculus oral composition
An oral dentifrice composition such as a toothpaste, dental gel, toothpowder, dental tablet or lozenge containing as anticalculus agent about 4.3% to about 7% of alkali metal pyrophosphates comprising at least 4.3% of tetrapotassium pyrophosphate alone or admixed with up to 2.7% of tetrasodium pyrophosphate, and as inhibitors against enzymatic hydrolysis of such agent in saliva, a fluoride and preferably up to about 3% of a synthetic anionic polymeric polycarboxylate, and use of such composition in a program of oral hygiene and/or for inhibiting dental calculus.
US08535724B2 Compositions containing resveratrol and pectin
The present invention relates to compositions, preferably in the form of a powder and/or granules, which contain resveratrol and pectin, and a process for the manufacture of such compositions.
US08535722B2 Functionally graded biocompatible coating and coated implant
The present invention provides a biocompatible coating comprising calcium phosphate that is functionally graded across the thickness of the coating. The coating, which preferably includes hydroxyapatite, is particularly useful for coating implants, such as dental or orthopedic implants. The functionally graded coating is generally crystalline near the interface with the surface of the implant, with crystallinity and crystal diameter decreasing toward the outer layer of the coating. The invention further provides methods for preparing a coated implant comprising a functionally graded calcium phosphate coating thereon. Furthermore, an antimicrobial agent can be dispersed within the calcium phosphate coating at discrete locations to provide for a coating with tailored release of the antimicrobial agent.
US08535721B2 Pharmaceutical microspheres containing valproic acid for oral administration
The subject of the invention is pharmaceutical microspheres containing, as active principle, a mixture of valproic acid and of one of its pharmaceutically acceptable salts in combination with a matrix vehicle selected from glycerol esters, hydrogenated oils, esterified polyethylene glycols, waxes and their mixtures.
US08535719B2 Biohybrid elastomeric scaffolds and methods of use thereof
Provided herein is a biohybrid elastomeric scaffold comprising a synthetic polymeric component and a biological polymeric component. The scaffold can be fabricated to have many different forms, non-limiting examples of which include a non-woven fibrous mesh or in a porous composite. Methods of use of the biohybrid elastomeric scaffolds in wound healing and tissue regeneration are also provided.
US08535718B2 Dosage forms of bisphosphonates
Provided is an oral dosage form comprising a bisphosphonate selected from the group consisting of a risedronate and salts thereof; an ethylenediaminetetraacetic acid (EDTA) or a pharmaceutically acceptable salt thereof; and a delayed release mechanism to deliver the risedronate and the EDTA in the lower gastrointestinal tract, wherein the oral dosage form is administered according to a scheduled dosing interval. The present invention substantially alleviates the interaction between bisphosphonates and food or beverages, which interaction results in the bisphosphonate active ingredient not being available for absorption. The resulting oral dosage form may thus be taken with or without food. Further, the present invention effects delivery of the bisphosphonate and the chelating agent to the lower GI tract, substantially alleviating the upper GI irritation associated with bisphosphonate therapies. These benefits simplify previously complex treatment regimens and can lead to increased patient compliance with bisphosphonate therapies.
US08535715B2 Bilayer tablet formulations
The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
US08535711B2 Medication disposal system
The potential for environmental release of unused and expired medications is reduced by the provision of a system and method for combining the unused or expired medication with an amount of activated carbon as part of a disposal procedure.
US08535709B2 Agents for controlling biological fluids and methods of use thereof
Therapeutic formulations adapted for positive-pressure application for controlling biological fluid at a desired site in a subject, absorbent articles comprising therapeutic formulations, and anti-infective devices coated with therapeutic formulations, said formulations comprising about 25% to about 99% by weight liquid-crystal forming compound and 0% to about 75% by weight solvent. In addition, methods of using said formulations including methods for controlling biological fluid at a desired site in a subject, methods for controlling blood loss, and methods for facilitating effective closure of a vascular wound or incision site at a desired site in a subject are disclosed, the methods comprising administering particular formulations comprising liquid-crystal forming compounds and solvents that are described herein.
US08535705B2 Biocompatible polymers and hydrogels and methods of use
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic groups capable of reacting and crosslinking in situ. Methods for making the resulting biocompatible crosslinked polymers biodegradable or not are provided, as are methods for controlling the rate of degradation. The crosslinking reactions may be carried out in situ on organs or tissues or outside the body. Applications for such biocompatible crosslinked polymers and their precursors include controlled delivery of drugs, prevention of post-operative adhesions, coating of medical devices such as vascular grafts, wound dressings and surgical sealants.
US08535704B2 Self-assembling cross-linking molecular nano film
The present invention is a molecular nano film formed on a surface of an implantable medical device to provide a barrier to tissue attachment. The film comprises self-assembling cross-linking molecules.
US08535702B2 Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
The present invention relates to phase separated polymeric regions and to their use in conjunction with implantable or insertable medical devices. In some aspects of the invention, phase separated polymeric regions are provided that include (a) at least one biostable polymeric phase and (b) at least one biodisintegrable polymeric phase, which is of nanoscale dimensions and which undergoes biodisintegration such that the phase separated polymeric region becomes a nanoporous polymeric region in vivo. Other aspects of the invention are directed to methods of making implantable or insertable medical devices having at least one nanoporous polymeric region. These methods include (a) providing a phase separated polymeric region comprising a stable polymeric phase and a disintegrable polymeric phase of nanoscale dimensions, (b) selectively removing the disintegrable polymeric phase thereby producing the nanoporous polymeric region. In still other aspects, implantable or insertable medical devices are provided which have phase separated polymeric regions that include (a) at least one block copolymer having at least one biostable polymer block and at least one biodisintegrable polymer block and (b) at least one therapeutic agent which is released in vivo upon implantation or insertion of the medical device.
US08535698B2 Granular water dispersible agent and production process
A water dispersible granule formulation prepared by pulverized a part of active ingredients into fine particles under wet milling and pulverized another part of the active ingredients into coarse particles under dry milling, then kneading the both active ingredients for the granulation, and a process for producing the water dispersible granule formulation are disclosed. The water dispersible granule formulation according to the present invention is applicable from production of a water dispersible granule formulation comprising an active ingredient which is easily decomposed owing to environmental conditions and allows to provide the water dispersible granule formulation provided with enhanced initial and residual biological activities.
US08535695B2 Pharmaceutical compositions and related methods of delivery
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.
US08535694B2 Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or condition using the disclosed compositions. According to aspects illustrated herein, there is provided a pharmaceutical composition that includes a calcineurin inhibitor or an mTOR inhibitor; a first surfactant with an HLB index greater than about 10; and a second surfactant with an HLB index of greater than about 13, wherein an absolute difference between the HLB index of the first surfactant and the HLB index of the second surfactant is greater than about 3, and wherein the composition forms mixed micelles.
US08535691B2 Perflurochemical treatment process and apparatus
A subject is confined in a closed environment at an elevated pressure through which perfluorochemical fluid containing dissolved oxygen is circulated to treat disease or injury.
US08535690B2 Tumor specific animal proteins
CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal cancers, autoimmune diseases, and related conditions.
US08535689B2 Identification of bacterial autoinducer and use in treating bacterial pathogenicity
A bacterial autoinducer, CAI-1, was purified and its structure identified. Methods for synthesis of the autoinducer and its analogues were elucidated. Methods of using the autoinducer or its analogues for treating bacterial pathogenicity and bio film formation are described. Methods for prevention and treatment of cholera are described. Synthetic (S)-3-hydroxytridecan-4-one functions as well as natural CAI-1 in repressing production of the virulence factor toxin co-regulated pilus (TCP). Strategies are described to manipulate bacterial quorum sensing in the clinical arena.
US08535686B2 Recombinant HCV E2 glycoprotein
The invention provides modified hepatitis C virus (HCV) E2 glycoproteins comprising the HCV-E2 receptor-binding domain (RBD) including the HVR1, HVR2 and igVR variable regions wherein in at least one of said variable regions at least a part of the variable region is replaced with a flexible linker sequence. The invention also provides vaccine compositions comprising the modified glycoproteins as well as methods of use thereof.
US08535682B2 Recombinant vaccine against West Nile Virus
An immunogenic or vaccine composition to induce an immune response or protective immune response against West Nile virus (WNV) in an animal susceptible to WNV. The composition includes a pharmaceutically or veterinarily acceptable vehicle or excipient, and a vector. The vector contains heterologous nucleic acid molecule(s), expresses in vivo in the animal WNV antigen, immunogen or epitope thereof, e.g., WNV E; WNV prM and E; WNV M and E; WNV prM, WNV M and E, WNV polyprotein prM-E, WNV polyprotein M-E, or WNV polyprotein prM-M-E. The composition can contain an adjuvant, such as carbomer. Methods for making and using such a composition, including prime-boost regimes and including as to differential diagnosis, are also contemplated.
US08535675B2 Compositions and methods for the diagnosis and treatment of tumor
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
US08535670B2 Method of treating colorectal cancer tumor
The present invention relates to mutations in Epidermal Growth Factor Receptor (EGFR) and methods of detecting such mutations as well as prognostic methods method for identifying a tumors that are susceptible to anticancer therapy such as chemotherapy and/or kinase inhibitor treatment. The methods involve determining the presence of a mutated EGFR gene or mutated EGFR protein in a tumor sample whereby the presence of a mutated EGFR gene or protein indicates the tumor is susceptible to treatment.
US08535669B2 Methods of treating lupus by administering humanized anti-interleukin 3 receptor alpha chain antibodies
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.
US08535663B2 Method for treating delayed-type hypersensitivity
The invention is directed to treatment of delayed-type hypersensitivity reactions associated with changes of qualitative and/or quantitative composition of blood extracellular DNA and treatment of systemic DNA mutation diseases accompanied with development of somatic mosaicism and elevation of blood extracellular DNA. The inventive method comprises introducing a DNASE enzyme into the systemic blood circulation of a patient in doses and regimens which are sufficient to decrease average molecular weight of circulating extracellular blood DNA in the blood of said patient.
US08535660B1 Nutritional supplements for pregnant women
The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.
US08535657B2 Stabilized pharmaceutical formulations that contain the interferons gammas and alpha in synergistic proportions
The present invention is related to stable pharmaceutical formulations to be applied by parenteral (liquids or freeze-dried), or topic way (gel, unguent or cream) that contain different quantities of the recombinant interferons gamma and alpha in synergistic proportions for the treatment of pathological events that contemplate the malignant or benign not-physiological growth of cells in tissue or organs.
US08535656B2 Amphiphilic polymer-protein conjugates and methods of use thereof
Compositions and methods for transporting biologically active proteins and polypeptides, particularly across the blood-brain barrier, are provided.
US08535655B2 Biodegradable polymer—bioactive moiety conjugates
The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone.
US08535654B2 Disinfecting and detoxifying meta-aramid particles
Porous, permeable particles of meta-aramid can be chlorinated or brominated to produce antimicrobial and detoxifying particles for use in applications such as, but not limited to, nonwoven webs, paper, textiles, absorbent articles, healthcare products, paints, filter materials, powder coatings, clear coatings, molded plastic articles, binders for fibrous materials, and the like. The particles can be charged with halogen before or after incorporation into the application medium. The particles can contain blends of meta-aramid with other polymers such as, but not limited to, cellulose, cellulose acetate, polyurethane, and the like. The particles will be effective at inactivation of pathogenic and odor-causing microorganisms and toxic chemical agents. The particles, which contain N-halamine units, have unexpected resistance to ultraviolet light degradation.
US08535652B2 Soap-free, self-foaming gel based on N-acylsarcosine; shaving method; cleansing method
One subject of the invention is a soap-free, self-foaming gel comprising, in a cosmetically acceptable medium: a) at least one aqueous phase; b) at least one N-acylsarcosine where the acyl radical is a C10-C20 radical in an amount less than 4 wt % relative to the total weight of the composition; c) at least one mineral or organic base in an amount sufficient to dissolve the N-acylsarcosine and produce a pH of 4 to 8; d) at least one amphoteric or zwitterionic surfactant; e) at least one non-ionic surfactant; and f) at least one self-foaming agent. The present invention also relates to a shaving method consisting in applying a self-foaming gel as defined above to the surface of the skin to be shaved, then in shaving the hairs using a razor.The present invention also relates to a method for cleansing the skin and more particularly the face, consisting in applying a self-foaming gel as defined above to the surface, followed by rinsing with water.
US08535649B2 Cosmetic composition including an anhydrous gel and a glyceryl ester
The present invention relates to a cosmetic composition including, in a physiologically acceptable medium: (a) at least 30% by weight of an anhydrous gel having a viscosity of at least 180 000 cP-s at 25° C. which includes at least one oil and at least one copolymer of styrene and at least one olefin other than styrene; (b) at least one specific glycerol diester; and (c) optionally at most 10% by weight of wax(es), the composition exhibiting a phase shift δ between its elastic modulus (G′) and its viscous modulus (G′) of less than 45° at a frequency of 30 to 50 Hz. It also relates to a cosmetic method for caring for or making up the lips, including the topical application to the lips of the abovementioned composition.
US08535648B2 Stabilization of UV-sensitive active ingredients
Disclosed is the use of merocyanine derivatives of formula (1) for stabilizing UV-sensitive active ingredients like dibenzoylmethane derivatives.
US08535646B2 Method of inhibiting harmful microorganisms and barrier-forming composition therefor
A method for blocking, neutralizing, or killing microorganisms that cause infectious disease in a mammal prior to or during the mammal encountering a contaminated environment or item includes: identifying a contaminated environment or item, wherein the contaminated environment or item is known or expected to be contaminated with harmful viral, fungal, or bacterial microorganisms; and administering a therapeutically effective amount of a barrier-forming composition to a mucosa of the mammal prior to or during the mammal encountering the contaminated environment or item. The barrier-forming composition provides a barrier on the mucosa that inhibits the microorganisms from contacting the mucosa. Other related methods are also included.
US08535643B2 Flourescent dendrimer compounds and use of such compounds in multi-photon devices or processes
Fluorescent chemical compound composed of an n-generation dendrimer, n being a non-zero integer, exhibiting: —at least one central nucleus (N) with a valency of m, selected from the group consisting of—at least one first, non-chromophoric unit (X) with a valency of m′, and—at least one second unit (Y) which exhibits two-photon absorption properties, with a valency of m″.
US08535642B2 Contrast agents
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two linked iodinated phenyl groups of the general formula R—N(CO—CH3)—X—N(CO—CH3)—R and salts or optical active isomers thereof, wherein X denotes a divalent linking moiety with 5 to 10 bridge elements of carbon, oxygen, sulphur and nitrogen separating the acetylated nitrogen atoms, and which may be further substituted by hydroxyl groups, by C1 to C4 alkyl moieties optionally substituted by hydroxyl groups, by C1 to C4 alkoxy groups, by amino groups and by C1 to C4 alkylamino groups, and wherein 2 or 3 carbon bridge elements together with alkyl or alkoxy groups form a cyclopentane, cyclohexane, pentahydropyran or tetrahydrofuran entity which may be alkyl- or hydroxyalkyl-substituted and each R denotes a triiodinated phenyl residue further substituted by hydrophilic moieties. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging, and to contrast media containing such compounds.
US08535639B2 Trifunctional imaging agent for monoclonal antibody tumor-targeted imaging
The present invention relates to trifunctional imaging agents that include an antibody for cell targeting, as well as a chelating moiety for sequestering radioisotopes and a fluorescing moiety for imaging. The invention also provides methods using the conjugates for medical diagnostic imaging.
US08535638B2 Process for recovering hydrogen and carbon dioxide
The present invention provides a process for recovering hydrogen and carbon dioxide from a process stream of a process unit wherein the process stream contains at least carbon dioxide, hydrogen, and methane.
US08535635B2 Method of manufacturing carbon cylindrical structures and biopolymer detection device
A method of manufacturing carbon cylindrical structures, as represented by carbon nanotubes, by growing them on a substrate using a chemical vapor deposition (CVD) method, comprising the steps of implanting metal ions to the substrate surface and then growing the carbon cylindrical structures using the metal ions as a catalyst. A method of manufacturing carbon nanotubes comprising a step of using nano-carbon material as seed material for growing carbon nanotubes is also disclosed. A biopolymer detection device comprising vibration inducing part for inducing vibration, binding part capable of resonating with the vibration induced by the vibration inducing part and capable of binding or interacting with a target biopolymer, and detection part for detecting whether or not the binding part have bound or interacted with the target biopolymer, is also disclosed.
US08535634B2 Iron nitride powders for use in magnetic, electromagnetic, and microelectronic devices
A method of making iron nitride powder is provided. The method comprises the steps of: a) providing an iron-based starting material; b) reducing the starting material by heating the starting material in a fluidized bed reactor in the presence of a reducing agent; c) nitriding the material obtained from step (b) by contacting the material with a nitrogen source. Also provided is the iron nitride powder made by the above method.
US08535633B2 Process for the production of doped metal oxide particles
Process for the production of doped metal oxide particles, wherein the doping component is present on the surface in the form of domains, wherein in a first reaction zone, an oxidizable and/or —hydrolysable metal compound as dopant together with an atomization gas is atomized into a flow of metal oxide particles in a carrier gas, wherein the mass flow of the metal oxide particles und —the mass flow of the dopant are selected such that the doped metal oxide particles contain 10 ppm to 10 wt. % of the doping component, where the quantity of dopant to be introduced is calculated as the corresponding oxide, and wherein the temperature in the first reaction zone is —selected such that it is below the boiling temperature of the dopant under the prevailing reaction conditions, and then, in a second reaction zone, the flow from the first —reaction zone and optionally at least as much oxygen and/or steam are —introduced that the quantity of oxygen and/or steam at least suffices completely to convert the dopant, wherein the temperature is from 300 to 2000° C., —preferably 500 to 1000° C., and the reaction mixture is then cooled or allowed to cool and the doped metal oxide particles are separated from the gaseous substances.
US08535632B2 Ceramic nanofibers containing nanosize metal catalyst particles and medium thereof
The present invention relates to a catalyst-containing nanofiber composition, comprising a ceramic nanofiber having a plurality of metal catalysts wherein the metal catalysts exist as dispersed particles partially embedded in the nanofiber and cover from about 1% to about 90% of the surface area of the ceramic nanofiber.
US08535631B2 Method for the catalytic removal of carbon dioxide and sulphur dioxide from exhaust gases
A method for the catalytic removal of sulphur dioxide and carbon dioxide from waste gases in a reactor charged with an activated carbon catalyst, includes saturating the activated carbon with SO2, saturating or partially saturating waste gases with water, introducing the waste gases with water, introducing the exhaust gases into the reactor catal ticall convertin the SO2 into H2SO4 and CO2 into C and O2 and into sulphur-carbon compounds on the same catalyst, washing out the catalyst and discharging the H2SO4 as a liquid and the C as a solid and/or bound to sulphur compounds.
US08535630B2 Method and apparatus for SOx and CO2 removal from flue gas
The present invention relates to a method for combined SO2 and CO2 removal from flue gas, which includes removing both CO2 and SO2 in a primary fractionation column and two polishing columns, the method comprising: a) hot flue as pretreatment, including flue gas SO3 removal by dry sorbent injection; b) compressing the treated hot flue gas by a multi-stage compressor; c) separation of CO2, SO2 and non-condensable gases; d) subjecting the CO2 and SO2 to separate polishing columns; and e) combining streams from the primary fractionation column and the two polishing columns for power recovery.
US08535629B2 Zeolite catalyst containing metal
Provided is a catalyst comprising (a) a zeolite material having a mean crystal size of at least about 0.5 μm, having a CHA framework that contains silicon and aluminum, and having a silica-to-alumina mole ratio (SAR) of about 10 to about 25; and (b) an extra-framework promoter metal (M) disposed in said zeolite material as free and/or exchanged metal, wherein the extra-framework promoter metal is copper, iron, and mixtures thereof, and is present in a promoter metal-to-aluminum atomic ratio (M:Al) of about 0.10 to about 0.24 based on the framework aluminum; and optionally comprising (c) at least about 1 weight percent of cerium in said zeolite material, based on the total weight of the zeolite, wherein said cerium is present in a form selected from exchanged cerium ions, monomeric ceria, oligomeric ceria, and combinations thereof, provided that said oligomeric ceria has a particle size of less than 5 μm.
US08535626B1 Exhaust gas treatment apparatus and exhaust gas treatment method
An exhaust gas treatment apparatus according to the present invention generates post-mercury oxidation exhaust gas by denitrating exhaust gas of a combustion apparatus, generates desulfurization drainage by desulfurizing the post-mercury oxidation exhaust gas, supplies the desulfurization drainage to the combustion apparatus, and controls a return amount, which is the amount of the desulfurization drainage reused for the desulfurization, based on a concentration of halogens in the desulfurization drainage. Such exhaust gas treatment apparatus can appropriately remove mercury from the exhaust gas, and can desulfurize the post-mercury oxidation exhaust gas more appropriately.
US08535623B2 Concave connector substrate, method of manufacturing the same, measuring kit, sensor substrate, and sensor substrate interprolated cylinder
A method of manufacturing a concave connector substrate includes: a step of preparing a guide substrate having a guide/holding region that guides a plate-shaped connector to a connection position and a cut portion; a step of arranging and aligning two wiring substrates, each having wiring lines and through hole connection portions that are electrically connected to the wiring lines, with both surfaces of the guide substrate, and applying an adhesive to a predetermined region of the guide substrate to bond the wiring substrates to the guide substrate; a step of bending a portion of the wiring substrate toward the inside of the cut portion of the guide substrate and bringing the wiring lines disposed in the bent portion into pressure contact with the inside of the cut portion; and a step of removing a section inside the cut portion to form the guide/holding region.
US08535617B2 Blood cell barrier for a lateral flow device
A lateral flow device for analyzing a whole blood sample is provided. More specifically, the lateral flow device contains a porous membrane that defines a barrier zone for separating red blood cells from blood plasma (includes plasma in which clotting factors haven been removed), which may then flow to a subsequent detection zone for analysis. The barrier zone is formed from a blood cell barrier composition that includes an unsaturated aliphatic fatty acid or an ester thereof. Without intending to be limited by theory, the present inventors believe such unsaturated aliphatic fatty acid molecules undergo autoxidation in the presence of air and hemoglobin to release peroxides (e.g., hydrogen peroxide) via oxidative saturation of double bonds. In turn, the released peroxides are believed to induce the formation of echinocytes or crenated blood cells. The crenated red blood cells are distorted in shape and less flexible and malleable than normal red blood cells, making them less able to penetrate into the pores of the porous membrane of the lateral flow device. Consequently, the stiffer, less flexible cells cannot move easily into the porous and become trapped at the surface of the membrane, while the liquid components of the sample flow and penetrate through the membrane to the detection zone for analysis.
US08535615B2 Radical sterilization apparatus
To provide a radical sterilization apparatus which can generate hydroxy (OH) radical and oxygen (O) radical at a high density to thereby surely and economically sterilize a subject to be treated. While maintaining a storage unit in which a medical instrument is stored at a low pressure by using a low pressure-maintaining unit, vapor is supplied form a vapor-supplying unit into the storage unit. Then, oxygen in this vapor is converted into radicals by a radical-forming unit to give hydroxy (OH) radical and oxygen (O) radical. Thus, the hydroxy radical and the oxygen (O) radical can be maintained each as a single radical over a long period of time and can be generated at a high density, which makes it possible to surely and economically sterilize the medical instrument.
US08535603B2 Rotary degasser and rotor therefor
A device for dispersing gas into molten metal includes an impeller, a drive shaft having a gas-transfer passage therein, and a first end and a second end, and a drive source. The second end of the drive shaft is connected to the impeller and the first end is connected to the drive source. The impeller includes a first portion and a second portion with a plurality of cavities. The first portion covers the second portion to help prevent gas from escaping to the surface without entering the cavities and being mixed with molten metal as the impeller rotates. When gas is transferred through the gas-transfer passage, it exits through the gas-release opening(s) in the bottom of the impeller. At least some of the gas enters the cavities where it is mixed with the molten metal being displaced by the impeller. Also disclosed are impellers that can be used to practice the invention.
US08535598B2 Method of forming hollow foam moldings
A method for producing a hollow foam molding having a thin and uniform wall thickness, including extruding a foamable melt containing a polypropylene resin having an equilibrium compliance Jeo of 0.5×10−3 to 1.8×10−3 Pa−1 and a swell ratio Sw of 2.5 or less and a physical blowing agent through a die to obtain a parison having a softened polypropylene resin foam layer, placing the parison in a mold, and blowing a gas into the parison to obtain a hollow foam molding having a hardened polypropylene resin foam layer with an apparent density of 0.35 to 0.65 g/cm3.
US08535595B2 Embossed decorative injection-molded product and method of manufacturing the same
The present invention relates to a decorated injection molded article having an embossed pattern comprising a surface layer comprising an acryl resin film, a printing layer provided on an inside of the surface layer, an adhesive layer provided on an inside of the printing layer and an injected resin layer, wherein a concavo-convex pattern is provided on the surface of the surface layer at a front face part and a side face part of the injection molded article by emboss processing and further to a method for producing the same, and the present invention provides a decorated injection molded article having an embossed pattern, in which a concavo-convex pattern is easily formed on the surface and which is imparted with a steric design property having a higher grade feeling.
US08535594B2 Method for producing hollow bodies from plastic and hollow plastic bodies with novel properties
A hollow plastic body comprises a material composite consisting of a stamp-formed panel or sheet-like first layer of a first thermoplastic synthetic material, an optionally stamp-formed panel or sheet-like second layer of a second synthetic material, and an open-cell or mixed-cell foam layer of a third synthetic material disposed between the first and the second layer. The foam layer may be compressed at least in some sections in accordance with the stamped form of the first layer and/or the second layer. The foam layer may be in mechanical contact with the first or/and second layer substantially only in the compressed sections. Advantageous manufacturing methods for hollow plastic bodies are further disclosed.
US08535589B2 Floor covering, floor panels for forming such floor covering, and method for realizing such floor panels
Floor covering, consisting of hard panels, with a laminated structure, whereby at least at the upper surface a printed decorative layer with a wood pattern is present, with thereupon a transparent layer of synthetic material in which impressions are formed, wherein the impressions substantially follow the wood pattern.
US08535583B2 Hydraulic binder product
The invention relates to a hydraulic binder product [12, 10] which includes a mixture of a hydraulic binder [38, 202], a polyvinyl alcohol [14, 204] and a gelling agent [54] which reacts with the polyvinyl alcohol and a method [8] of producing same.
US08535573B2 Copper fine particles, method for producing the same, and copper fine particle dispersion
A method for producing copper fine particles by heating and reducing an oxide, hydroxide, or salt of copper included in a solution of ethylene glycol, diethylene glycol, or triethylene glycol, the method comprising controlling a total halogen content of the solution to be less than 20 ppm by mass relative to copper and adding a water-soluble polymer as a dispersant such as polyethyleneimine and a noble metal compound or noble metal colloid for nucleation to the solution. This method makes it possible to provide copper fine particles for use in a wiring material, which are very fine as small as 50 nm or less in average particle size and high dispersibility, extremely low undesirable halogen content, and can be sintered at a low temperature.
US08535564B2 Light emitting device employing luminescent substances with oxyorthosilicate luminophores
A light emitting device having oxyorthosilicate luminophores is disclosed. The light emitting device includes a light emitting diode and luminescent substances disposed around the light emitting diode, to absorb at least a portion of light emitted from the light emitting diode and emitting light having different wavelength from that of the absorbed light. The luminescent substances have Eu2+-doped silicate luminophores in which solid solutions in the form of mixed phases between alkaline earth metal oxyorthosilicates and rare earth metal oxyorthosilicates are used as base lattices for the Eu2+activation leading to luminescence. The luminescent substances are used as radiation converters to convert a higher-energy primary radiation, for example, ultra violet (UV) radiation or blue light, into a longer-wave visible radiation and are therefore preferably employed in corresponding light-emitting devices.
US08535563B2 Liquid crystal composition and liquid crystal display device
Provided is a liquid crystal composition that satisfies at least one of characteristics such as high maximum temperature of a nematic phase, low minimum temperature of a nematic phase, small viscosity, large optical anisotropy, large positive dielectric anisotropy, large specific resistance, high stability to ultraviolet light and high stability to heat, or that is suitably balanced between at least two of the characteristics; and provided is an AM device that has a short response time, a large voltage holding ratio, a large contrast ratio, a long service life, etc. The liquid crystal composition includes a specific four-ring compound having high maximum temperature as a first component, a specific three-ring compound having large optical anisotropy and large dielectric anisotropy as a second component, and a specific three-ring compound having large dielectric anisotropy as a third component, and has a nematic phase. The liquid crystal display device contains this composition.
US08535562B2 Liquid crystal composition and liquid crystal display device
Provided is a liquid crystal composition satisfying at least one of characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of the nematic phase, a small viscosity, a large optical anisotropy, a large dielectric anisotropy, a large specific resistance, a large elastic constant, a high stability to ultraviolet light and a high stability to heat, or having a suitable balance regarding at least two of the characteristics. Also provided is an AM device having a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth. The liquid crystal composition contains a specific compound having a large elastic constant as a first component, and a specific compound having a large dielectric anisotropy as a second component, and has a nematic phase, and a liquid crystal display device contains the composition.
US08535560B2 Ionic liquids for separation of olefin-paraffin mixtures
The invention is directed to an ionic liquid comprising (i) a cationic portion containing a complex of a silver (I) ion and one or more neutral ligands selected from organoamides, organoamines, olefins, and organonitriles, and (ii) an anionic portion having the chemical formula wherein m and n are independently 0 or an integer of 1 or above, and p is 0 or 1, provided that when p is 0, the group —N—SO2—(CF2)nCF3 subtended by p is replaced with an oxide atom connected to the shown sulfur atom. The invention is also directed to a method for separating an olefin from an olefin-paraffin mixture by passing the mixture through a layer of the ionic liquid described above.
US08535548B2 Non-contact etching of moving glass sheets
Methods and apparatus are disclosed for etching flexible glass sheets (13) in which the sheets (13) are transported in a near vertical orientation past non-contact, liquid-ejecting bearings (3) which apply an etching solution (e.g., an aqueous NaF/H3PO4 solution) to the sheets (13). In certain embodiments, the uppermost liquid-ejecting bearing (3) is above the top edge of the sheet (13) and thus is able to apply etching solution to the top of the sheet. In other embodiments, a top shower (11), which includes a set of spray nozzles (21) located above and distributed along the length of the apparatus, is used to apply etching solution to the top of the sheet (13). Using the disclosed methods and apparatus, glass sheets (13) produced by a fusion process are provided which have areas greater than five square meters and average surface roughness values in the range of 0.5 nanometers to 1.1 nanometers.
US08535539B2 Water softener system and method
A method for regenerating the ion exchange resin bed of a resin tank for a water treatment system is provided. This method includes supplying a first pulse of regenerate solution into the resin tank to charge a first section of the ion exchange resin bed, and supplying a second pulse of regenerate solution to charge a second section of the ion exchange resin bed.
US08535537B2 Devices for and methods of monitoring a parameter of a fluidic sample by microdialysis
A device for monitoring a parameter of a fluidic sample by microdialysis, the device comprising a permeable membrane, wherein the permeable membrane has a first surface to be brought in contact with the fluidic sample to traverse the permeable membrane (300), wherein the permeable membrane has a second surface to be brought in contact with a dialysis fluid, and wherein the first surface is smoother than the second surface.
US08535534B2 Solids retention time uncoupling by selective wasting of sludge
Fluorescence in situ hybridizations were used to identify and determine the abundance of nitrifying bacteria and Anammox bacteria (recycling bacteria) in freshly settled sludge of biological nutrient removal (BNR) secondary clarifiers. An uneven distribution was observed for recycling bacteria in two BNR systems. Settling patterns suggest microcolony formation processes are sensitive to the internal recycle rate, which allow for rapid recycling bacteria microcolony growth by increasing circulation of flocs through the aeration and anoxic basins. Sludge containing high levels of recycling bacteria are selectively collected and separated from the remaining sludge, uncoupling the solids retention time (SRT) of the recycling bacteria from the wasting bacteria. Elevated recycling bacteria SRTs increase concentrations of nitrifying bacteria in the aeration basin and Anammox bacteria in the anoxic basin, improving nitrification and anaerobic ammonium oxidation. Uncoupling the SRT enhances aeration and/or anoxic basin utilization and reduces the overall hydraulic residence time.
US08535533B2 Bioretention system with high internal high flow bypass
The invention provides a bioretention system comprising one or more chambers and a high flow bypass system with top and bottom weirs for water filtration and storm water flow management. The invention also provides methods that are useful for managing storm water flow and inhibiting the flow of pollutants, debris, and other contaminants into drainage systems.
US08535531B2 Halogenated resin beds
A water treatment system may generally comprise a generally cylindrical halogenated resin bed comprising an empty bed contact time greater than 1 second, an aspect ratio less than 0.8, and a fluid velocity less than 0.5 cm/s, wherein the aspect ratio is the ratio of the length of the halogenated resin bed to the diameter of the halogenated resin bed; and wherein the fluid velocity is the quotient of the volumetric flow rate of the water treatment system and the cross-sectional area of the halogenated resin bed; and wherein the halogenated resin bed improves the removal of contaminates relative to a corresponding water treatment system having an aspect ratio greater than 0.8.
US08535530B2 Liquid filter arrangement; components; and, methods
Liquid filter arrangements are described and shown. The arrangements generally include a filter head, a seal adaptor, and a filter member comprising a shell enclosing a cartridge. Unique features for interface between the filter cartridge and the filter head are provided. Also provided are unique filter head features and cartridge features.
US08535529B2 Canister filter system with drain that cooperates with filter element
A filter assembly with a replaceable filter element and a reusable filter housing, which incorporates a locking mechanism to ensure that the filter system will not be operated without a filter element installed.
US08535523B2 Fluid flow control and debris intercepting apparatus
A fluid flow control and debris intercepting apparatus for controlling the flow of fluid and the introduction of debris into the entrance of a water diversion system such as a curbside storm drain.
US08535521B2 Optimizing clearance for protein-bound molecules using cascade filtration therapy
A hemofiltration system or method removes unwanted molecules from a flow of blood using cascaded first and second hemofilters. Filtration of the blood in first hemofilter raises hemoconcentration of unwanted protein-bound molecules. Combination of a substitution fluid with outflow from the first hemofilter creates a concentration differential between bound and unbound molecules that frees unwanted molecules from protein bonds. Filtration of the combined fluids in a second hemofilter removes the unwanted free molecules. A second substitution fluid may be added to the twice filtered blood fluid for return to a patient. Removal of inflammatory mediators, apoptotic mediators, and certain electrolytes may be effected, and the removal may be optimized by controlling fluid flows and transmembrane pressures.
US08535520B2 Three-stage fuel filter
A fuel filter has a coalescent element for separating water from fuel, a prefilter element, a main filter element, and a common central tube, wherein the coalescent element, the prefilter element, and the main filter element are arranged sequentially along the common central tube. A fuel filter arrangement has a housing in which the fuel filter is arranged. The common central tube of the fuel filter is attached to the housing, wherein between the fuel filter and the housing an annular space is formed.
US08535515B2 Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof
The invention relates to a hydroconversion catalyst, which comprises a refractory oxide support, at least one metal selected from group VIII and at least one metal selected from group VIB and which is characterized in that it has at least one organic compound containing at least one oxime group of formula (I)>C═NOR1, in which R1 is selected among hydrogen and alkyl, allyl, aryl, alkylene or cycloaliphatic groups, and combinations thereof, these groups being able to be substituted by at least one electron donor group.
US08535512B2 Devices and methods for sequencing nucleic acids
Methods and devices for sequencing nucleic acids are disclosed herein. Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore. The capacitance can be measured for the DNA molecule passing through the nano-pore. The capacitance measurements can be correlated to determine the sequence of base pairs passing through the nano-pore to sequence the DNA.
US08535509B2 Membrane restoration
Embodiments include membrane restoration process. A membrane can be restored by replacing an anolyte and a catholyte of a cell with a solution having an organic acid. The cell can include an anode, a cathode and a membrane fouled with a metal. A cheleate can be formed with the metal and the organic acid of the solution and an electric current can be provided between the anode and the cathode of the cell to protect the cell from corrosion while forming the chelate.
US08535507B1 Electrochemical drilling system and process for improving electrical porosity of etched anode foil
A process for creating porous anode foil for use in an electrolytic capacitor of an implantable cardioverter defibrillator is provided. The process includes electrochemical drilling a plurality of etched metal foils in sequence one after the other in a bath containing electrochemical drilling (ECD) solution initially having a pH of less than 5. Alternatively, an etched foil sheet may be passed through the bath in a substantially continuous manner such that a portion of said etched foil sheet is in contact with the ECD solution is electrochemically drilled to generate pores. Electrochemical drilling is achieved when a current is passed to the foil or portion of the foil sheet in solution. ECD replenishment solution having a pH of less than about 5 is added from a feed reservoir to the bath at such a rate so as to maintain a pH in the ECD solution in the bath of less than about 5, and ECD solution in the bath is removed to a waste reservoir at the substantially the same rate as the addition of the ECD replenishment solution to the bath.
US08535503B2 Device with intermittent contact improved by dielectrophoresis
The device comprises first and second contact pads having a contact surface. The first and second contact pads move with respect to one another between an ohmic contact position between these contact surfaces and another position. The device further comprises means for applying a non-uniform electric field around the first contact pad. The electric field has a component in a direction parallel to the contact surface of the first contact pad. A fluid with a first dielectric permittivity value is arranged between the first contact pad and the decontamination electrode. The decontamination device and the fluid are configured in such a way that the electric field generates a force directed towards the decontamination electrode on a contaminant, by dielectrophoresis.
US08535500B2 Surface acoustic wave sensor device including target biomolecule isolation component
Provided herein is a surface acoustic wave (“SAW”) sensor device including an isolation component of a target biomolecule. A sample containing the target biomolecule is separated by its size using electrophoresis, and sequentially reacts with a SAW sensor. In other words, the device is capable of detecting the target biomolecule by separating biomolecules using electrophoresis, and applying the separated biomolecules to the SAW sensor.
US08535499B2 Microfabricated liquid-junction reference electrode
Micromachined reference electrodes for use in miniaturized electrochemical sensors, and methods for fabricating such reference electrodes and electrochemical sensors, for example, as a part of a microfluidic system, are disclosed. Electrochemical measurements allow for inexpensive detection of a wide variety of (bio-)chemical compounds in solution. The reference electrode is one of the main parts of an electrochemical cell. The reference electrode, from which no current is drawn, has a stable, constant potential.
US08535497B2 Method of measuring blood component, sensor used in the method, and measuring device
The present invention provides a method of measuring a component in blood, by which an amount of the component can be corrected accurately by measuring a hematocrit (Hct) value of the blood with high accuracy and high reliability and also provides a sensor used in the method. The sensor for measuring a component in blood has a first analysis portion and a second analysis portion. The first analysis portion has a first electrode system (11,12) and a reagent layer (14), and the reagent layer (14) has an oxidoreductase that acts on the component and a mediator. In the first analysis portion, the component in the blood is measured by causing a redox reaction of the component with the oxidoreductase in the presence of the mediator and detecting a redox current caused when a voltage is applied by the first electrode (11,12). The second analysis portion has a working electrode and a counter electrode, and a mediator is provided on the counter electrode but not on the working electrode. In the second analysis portion, a Hct value of the blood is measured by supplying the blood to the electrode system, applying a voltage to cause a current to flow, and detecting a value of the current. Using this Hct value, the amount of the component is corrected.
US08535494B2 Rotary magnet sputtering apparatus
Provided is a rotary magnet sputtering apparatus which includes a plasma shielding member and an outer wall connected to the ground and which has a series resonant circuit and a parallel resonant circuit between the plasma shielding member and the outer wall. The series resonant circuit has a very low impedance only at its resonant frequency while the parallel resonant circuit has a very high impedance only at its resonant frequency. With this configuration, the impedance between substrate RF power and the plasma shielding member becomes very high so that it is possible to suppress the generation of plasma between a substrate 10 to be processed and the plasma shielding member. Further, since a series resonant circuit is provided between a target and the ground, the RF power is efficiently supplied only to a region where the substrate passes under the target, so that a self-bias voltage is generated.
US08535488B2 Method and apparatus for purification of trichlorosilane
There is provided a method for a purification of trichlorosilane, the method including: performing a pretreatment for separating a chlorosilane mixture from reaction products of a trichlorosilane production reaction; performing a first purification for separating the chlorosilane mixture into a first top stream and a first bottom stream; performing a second purification for separating the first top stream into a second top stream and a second bottom stream; and performing a third purification for separating the second bottom stream into a third top stream and a third bottom stream, wherein the performing of the third purification is carried out under pressure conditions higher than those of the performing of the second purification, and a heat exchange is generated between the second bottom stream and the third top stream.
US08535484B2 Ultra-resilient fabric and method of making thereof
A structure for use in industrial fabrics such as paper machine clothing and engineered fabrics is disclosed. The structure includes one or more layers of an elastic nonwoven extruded film or sheet, which is elastic, resilient, and compressible in a thickness direction, and extensible, bendable, and resilient in its length and transverse directions, and one or more layers of a plurality of substantially parallel machine direction (MD) yarns in various patterns. The structure can also include one or more layers of a plurality of substantially parallel cross-machine direction (CD) yarns attached on top of or under the MD yarns. The structure has a high degree of both compressibility under an applied normal load and excellent recovery (resiliency or spring back) upon removal of that load.
US08535482B2 Dry fluff pulp sheet additive
A process is provided for making a fluff pulp sheet, comprising forming a web comprising fluff pulp fibers; and applying at least one debonder surfactant to the web, to make the fluff pulp sheet. A fluff pulp sheet is also provided, comprising a web comprising fluff pulp fibers; at least one debonder surfactant; and a fiberization energy of <145 kJ/kg. Products and uses of the fluff pulp sheet are also provided.
US08535481B2 Apparatus and method for degrading a web in the machine direction while preserving cross-machine direction strength
An embossing system for embossing at least a portion of a web is provided comprising a first embossing roll having male embossing elements, a second embossing roll having male embossing elements, wherein the first and second embossing rolls define a first nip for receiving the web, and a third embossing roll having male embossing elements, wherein the second and third embossing rolls define a second nip for receiving the web, and wherein at least a substantial portion of the embossing elements of at least one of the first, second, and third embossing rolls are substantially oriented in the cross-machine direction.
US08535469B2 Heat transfer masking sheet materials and methods of use thereof
In one embodiment, a method of applying an image to a substrate includes the steps of: imaging a printable surface with an image to form an imaged surface having a printed area and a non-printed area; positioning a masking sheet comprising an outer masking layer adjacent the imaged surface such that the outer masking layer is in contact with the imaged surface; transferring a corresponding portion of the outer masking layer to the printed area of the imaged surface, leaving a negative image mask on the masking sheet; transferring the negative image mask to a transfer layer of a heat transfer paper to form a heat transfer paper having a masked portion corresponding to the negative image mask and an unmasked portion; and transferring the unmasked portion corresponding to the printed area to a substrate. Other methods of making and using negative image masks are also disclosed.
US08535468B2 Method for making disposable bodily fluid handling composite pad
A method and an apparatus are provided for making a disposable bodily fluid handling composite pad having thickness-reduced regions on longitudinally opposite ends. The disposable bodily fluid absorbing composite pad includes a bodily fluid absorbing first pad and a bodily fluid absorbing second pad seperably attached to the first pad. A continuous web having continuous bodily fluid absorbing layer and bodily fluid impervious layer permanently attached together is fed to pass through paired compression rolls to obtain a worked web formed in regions which will become ends of the first pad with thickness-reduced regions. A bodily fluid absorbing web is seperably attached to the worked web to obtain a first composite web. A bodily fluid impervious web, pressure-sensitive adhesive and a separator are placed on the bodily fluid absorbing web of the first composite web to obtain a second composite web from which the composite pad is cut out.
US08535467B2 Process for manufacturing an anti-ballistic article
The invention relates to a process for the manufacture of an antiballistic article comprising the steps of forming a stack of sheets by stacking 2 or more sheets, each sheet comprising one or more mono-layers of anti-ballistic fibers and optionally a thermoplastic binder, followed by subjecting the stack of sheets to a reduced atmospheric pressure environment; and while maintaining the reduced atmospheric pressure environment, consolidating said stack of sheets to a pressure of at least 10 MPa at an elevated temperature. The invention also relates to an anti-ballistic article.
US08535465B2 Process and apparatus for manufacturing tyres for vehicle wheels
A carcass ply is built on a forming drum by application of a plurality of strip-like elements by the steps of: setting a width of these strip-like elements, setting a width of the overlapped part between two adjacent strip-like elements, setting a fitting diameter of the forming drum by calculating a corresponding extension of a radially external laying surface, and calculating a whole number of strip-like elements to be applied. The whole number of strip-like elements is applied by rotating the forming drum around a geometric rotation axis thereof, and applying pairs of strip-like elements by means of a first laying unit and a second laying unit located close to opposite portions of the forming drum relative to the geometric rotation axis. When the calculated whole number of strip-like elements is an odd number, before at least one application step, the first laying unit is shifted along an adjustment path orthogonal to the geometric rotation axis and substantially tangent to the radially external laying surface of the forming drum.
US08535461B1 Melted hot glue system for applying broadcast soil fumigation film to an agricultural field
A method and apparatus are provided for installing types of broadcast fumigation film, such as LDPE, HDPE, TIF and VIF, over a field treated with a fumigant. An elongate first film strip is extended across the field, with simultaneous fumigant injection under the film and a melted hot glue adhesive is applied to the first strip along a trailing longitudinal edge thereof. An elongate second film strip is applied across the field and juxtaposed across the first film strip with a leading longitudinal edge of the second film strip overlapping the trailing longitudinal edge of the first strip. The leading longitudinal edge of the second strip is pressed against trailing longitudinal edge of the first strip to adhesively interengage the first and second strips along a seam that joins the strips together.
US08535459B2 Steel material for hardening
The present invention provides a steel material for hardening, including chemical components, by mass %, of: C: 0.15 to 0.60%; Si: 0.01 to 1.5%; Mn: 0.05 to 2.5%; P: 0.005 to 0.20%; S: 0.001 to 0.35%; Al: over 0.06 to 0.3%; and total N: 0.006 to 0.03%, with a balance including Fe and inevitable impurities including B of not more than 0.0004%, in which a hardness R at a position 5 mm away from a quenching end measured through a Jominy-type end-quenching method specified in JIS G 0561, and a calculation hardness H at a position 4.763 mm away from the quenching end satisfy the following Equation (1). H×0.948≦R≦H×1.05  Equation (1)
US08535458B2 High-strength hot-rolled steel sheet and method for manufacturing the same
A steel sheet contains, on a mass percent basis, 0.03%-0.12% C, 0.5% or less Si, 0.8%-1.8% Mn, 0.030% or less P, 0.01% or less S, 0.005%-0.1% Al, 0.01% or less N, 0.035%-0.100% Ti, and the balance being Fe and incidental impurities and has microstructures with a fraction of polygonal ferrite of 80% or more, the polygonal ferrite having an average grain size of 5 to 10 μm. The amount of Ti present in a precipitate having a size of less than 20 nm is 70% or more of the value of Ti* calculated using expression (1): Ti*=[Ti]−48×[N]/14  (1) where [Ti] and [N] represent a Ti content (percent by mass) and a N content percent by mass), respectively, of the steel sheet.
US08535448B2 Methods of removing a protective layer
A method of removing a metal protective layer from a surface of a reactor component comprising treating the metal protective layer with one or more chemical removal agents to remove at least a portion of the metal protective layer from the reactor component. A method of removing a metal protective layer from a surface of a reactor component comprising treating the metal protective layer to remove the metal protective layer from the reactor component, and determining a thickness of the reactor component following treatment.
US08535446B2 Coating holder and coating device having same
A coating device includes a chamber, an evaporative source, a coating holder, and a supporting structure. The evaporative source is positioned at the bottom of the chamber. The coating holder is positioned at the top of the chamber and includes concentric annular parts with different diameters, and drive devices connected to the annular parts correspondingly. The drive devices are configured to move the annular parts along axial directions of the annular parts. Each annular part includes a bottom board defining receiving holes for receiving lenses. The supporting structure is positioned at the top of the chamber and supports the drive devices.
US08535445B2 Enhanced wafer carrier
A wafer carrier used in wafer treatments such as chemical vapor deposition has pockets for holding the wafers and support surfaces for supporting the wafers above the floors of the pockets. The carrier is provided with locks for restraining wafers against upward movement away from the support surfaces. Constraining the wafers against upward movement limits the effect of wafer distortion on the spacing between the wafer and the floor surfaces, and thus limits the effects of wafer distortion on heat transfer. The carrier may include a main portion and minor portions having higher thermal conductivity than the main portion, the minor portions being disposed below the pockets.
US08535443B2 Gas line weldment design and process for CVD aluminum
A system of gas lines for a processing chamber and a method of forming a gas line system for a processing chamber are provided. The system of gas lines includes electropolished multi-way valves that connect electropolished linear gas lines. By using multi-way valves rather than tee-fittings and electropolishing the linear gas lines, the nucleation of contaminating particles in the system of gas lines may be reduced.
US08535441B2 Crystal growth crucible lid
A lid for a crystal growth chamber crucible is constructed by forming arcuate sector-shaped portions and coupling them in abutting relationship, for example by welding, to form an annular profile fabricated lid. The arcuate sector-shaped portions may be formed and removed from a lid fabrication blank with less waste than when unitary annular lids are formed and removed from a similarly sized fabrication blank. For example, the sector-shaped portions may be arrayed in an undulating pattern on the fabrication sheet.
US08535439B2 Manufacturing method for silicon single crystal
To provide a manufacturing method for a silicon single crystal that can reduce introduction of dislocation thereinto even if a required amount of dopant is added to a melt while growing a straight body portion of a silicon ingot. In a manufacturing method for a silicon single crystal according to the present invention that includes a dopant addition step of adding a dopant to a melt while a straight body portion of a silicon single crystal is growing in a growth step of growing the silicon single crystal by dipping a seed crystal into a silicon melt and then pulling the seed crystal therefrom, in the dopant addition step, a remaining mass of the melt is calculated at the beginning thereof, and the dopant is added to the melt at a rate of 0.01 to 0.035 g/min·kg per minute per 1 kg of the calculated remaining mass of the melt.
US08535438B2 Chemically resistant glass composition for the manufacture of glass reinforcing strands
The present invention relates to a chemically resistant glass composition for the production of reinforcing strands which comprises the following constituents within the limits defined below, expressed in mol %: SiO2 67-72%; ZrO2 5-9.5%, preferably ≧7.5%; R2O (R=Na, K and Li) 11-17%; Li2O 0-5.5%; K2O 0-5.5%; Na2O<10%; and CaO 3-9%, the composition furthermore containing less 1% of impurities (Al2O3, Fe2O3, Cr2O3, TiO2, MgO, SrO, BaO and P2O5) and being free of F. It also relates to the glass strands obtained from this composition and to the composites based on an organic or inorganic material containing such strands.
US08535435B2 Method of fabrication of construction materials from industrial solid waste
A low-pressure method for producing construction materials, such as blocks, bricks or slabs, utilizing high percentages of waste cement dust in admixture with additive material capable of effectively neutralizing the high lime content and agglomerating the extremely fine particles of the cement dust upon blending of the admixture with water. The resulting blend may simply be cast in molds of various shapes and sizes and cured under normal atmospheric pressure conditions into a hardened construction material exhibiting high strength, light weight and high thermal insulation.
US08535432B2 Porphyrazine coloring matter, ink composition containing the same and colored product
The present invention relates to a porphyrazine coloring matter or a salt thereof represented by the following formula (1) [wherein, the rings of A to D are each independently a benzene ring or a 6-membered nitrogen-containing heteroaromatic ring, E is alkylene, X is a sulfo-substituted anilino group or the like which may further have a substituent, R1 is a C1-C6 alkyl group, b is 0.00 or more and less than 3.90 as an average value, c is 0.10 or more and less than 4.00 as an average value, and the sum of b and c is 1.00 or more and less than 4.00 as an average value]. The ink composition containing the porphyrazine coloring matter of the present invention has a good hue as a cyan ink, is excellent in various fastness properties, particularly in ozone fastness, allows a high print density, has properties hardly causing bronze phenomenon, and can provide a porphyrazine coloring matter suitable for inkjet recording and an ink composition containing this.
US08535426B2 Apparatus, system, and method for removing ethylene from a gaseous environment
An apparatus, system, and method are disclosed for removing ethylene from a gaseous environment. Ethylene is a gaseous growth hormone produced by plants that triggers the ripening of some flowers, fruits, vegetables, and other plants. The apparatus includes an ethylene filter and a composition. The filter includes a frame and a trapping medium. The composition is attached to the trapping medium of the ethylene filter. The ethylene filter is positioned within a gaseous environment and is configured to encounter a gas flow within the gaseous environment. The composition contains at least some titanium dioxide which is configured to attach to the ethylene as the gas flow moves through and around the ethylene filter. In this manner, some ethylene may be removed from the gaseous environment.
US08535424B1 Process and apparatus for separation of components of a gas stream
A process and apparatus for separating a gas mixture comprising providing a slot in a gas separation channel (conceptualized as a laterally elongated Clusius-Dickel column), having a length through which a net cross-flow of the gas mixture may be established; applying a higher temperature to one side of the channel and a lower temperature on an opposite side of the channel thereby causing thermal-diffusion and buoyant-convection flow to occur in the slot; and establishing a net cross-flow of a gas mixture comprising at least one higher density gas component and at least one lower density gas component along the length of the slot, wherein the cross-flow causes, in combination with the convection flow, a spiraling flow in the slot; and wherein the spiral flow causes an increasing amount of separation of the higher density gas from the lower density gas along the length of the channel. The process may use one or more slots and/or channels.
US08535419B2 Modular amine plant
A modular amine plant having a front-end module and a back-end module in fluid communication with each other. The front-end module having pre-fabricated connections for the association of various equipment including: a filter, an absorption tower, and a flash tank. The back-end module having pre-fabricated connections for the association of other various equipment including: a heat exchanger, a distillation tower, and a reboiler. The modular amine plant capable of being installed at a site in less than about 5 days. The modular amine plant further having moment forces sufficient to withstand wind speeds of about 100 miles per hour.
US08535417B2 Recovery of carbon dioxide from flue gas
Carbon dioxide-containing gas such as flue gas and a carbon dioxide-rich stream are compressed and the combined streams are then treated to desorb moisture onto adsorbent beds and then subjected to subambient-temperature processing to produce a carbon dioxide product stream and a vent stream. The vent stream is treated to produce a carbon dioxide-depleted stream which can be used to desorb moisture from the beds, and a carbon dioxide-rich stream which is combined with the carbon dioxide-containing gas.
US08535407B2 Hard-metal
The invention relates to a hard-metal comprising at least 13 volume % of a metal carbide selected from the group consisting of TiC, VC, ZrC, NbC, MoC, HfC, TaCl WC or a combination thereof, a binder phase comprising one or more of iron-group metals or alloy thereof and 0.1 to 10 weight % Si and 0.1 to 10 weight % Cr and having a liquidus temperature at 1280 degrees C. or lower and 3 to 39 volume % of diamond or cBN grains coated with a protective coating or a mixture thereof and a process for making the hard-metal.
US08535405B2 Honeycomb structure
The honeycomb structure is provided with a honeycomb structural section, a pair of lateral electrodes on the side face of the honeycomb structural section, and at least one intermediate layer between the honeycomb structural section and the lateral electrodes. The honeycomb structural section has silicon carbide particles having an average particle diameter of 3 to 40 μm and silicon, and the ratio (Si/SiC) of silicon (Si) to silicon carbide (SiC) is 10/90 to 40/60. The lateral electrodes have an average particle diameter of the silicon carbide particles of 10 to 70 μm and a Si/SiC ratio of 20/80 to 50/50. The intermediate layer has an average particle diameter of silicon carbide particles and Si/SiC between those of the honeycomb structural section and those of the lateral electrodes. The electric resistance between the lateral electrodes of the honeycomb structural section is 2 to 100Ω.
US08535402B2 Centrifugal particle reduction system and method
A particle reduction system and method is disclosed having an air stream accelerator, a feeder assembly, a variable speed wheel lock operably associated with the feeder assembly for releasing raw material into a conveying air stream created by the positive displacement pump, and a particle conditioning assembly. The raw material is carried by the conveying air stream through the particle conditioning assembly, where particle of the material are collided with each other for the purpose of reducing the size of the particles. In some embodiments, a non-thermal drying system can be used to extract moisture from the raw material. The moisture/solids separation occurs, in large part, due to a head-on collision of two conveying air streams. The collision creates a large squeezing force, much higher than a centrifuge or filter. This impact squeezing acts to squeeze the moisture out of the raw material.
US08535399B2 Use of hydroxyalkanoic acid derivatives as fuel additives
The present invention is related to the use of hydroxyalkanoic acid derivatives as a fuel additive. In particular, the present invention provides the use of lower alkyl esters and/or salts of hydroxyalkanoic acid as biofuels and/or fuel additives. The present invention also provides a fuel composition including at least one fuel and lower alkyl esters and/or salts of hydroxyalkanoic acid.
US08535394B2 Method for production of solid electrolyte and solid electrolytic capacitor
A method for producing a solid electrolyte, which includes the steps of applying a solution containing a five-membered heterocyclic compound as a polymerizable monomer on a substrate surface, and polymerizing the applied monomer to give a solid electrolyte. The monomer-containing solution contains the polymerizable monomer and at least one polymerizable compound selected from a dimer of the monomer and a trimer of the monomer, at a proportion satisfying the equation: A/(B+C)=100-1,000,000 where A: concentration of the polymerizable monomer, B: concentration of the dimmer in terms of the concentration of its monomer, and C: concentration of the trimer in terms of the concentration of its monomer. In another aspect, a method is disclosed wherein a solution of a compound having a thiophene skeletal structure, which solution has a light absorbance of 1.5-10 at 300-340 nm, is applied on a substrate surface and polymerized.
US08535392B2 Solid polymeric colorant compositions
This invention relates to solid forms of polymeric colorants and the methods and processes for manufacturing the solid colorants. These solid polymeric colorants may be provided in the form of a free-flowing powder and may be useful for coloring solid pucks, tablets, powder detergents, soaps, fertilizers, personal care products, adhesives, sealants, thermoplastic polymers, thermosetting polymers, and the like.
US08535390B1 Traction device and associated attachment device for a prosthetic running foot
A traction device for a prosthetic running foot having a curved profile and mechanisms for attaching the traction device to the prosthetic running foot are provided. The traction device includes a sole portion for traction and a midsole for improved rollover. The traction device has fasteners (e.g., clamps) that attach to the top of the prosthetic running foot or a cavity that removably receives the toe of the prosthetic running foot. The traction device also has a strap that removably couples to a clip permanently or removably attached to the top surface of the prosthetic running foot.
US08535389B2 Prosthetic socket liner
A removable liner used in conjunction with a socket for a prosthetic device, in which a vacuum is wicked across the entire area of a porous fabric of the liner, is disclosed. The liner preferably includes a shaped-layer made from one of either a silicone or a urethane and has an exterior surface, an interior surface and a passage therein which opens at each of the two surfaces and connects to a valve of the socket. The liner further includes a first porous fabric covering at least a portion of the exterior surface of the shaped-layer including the corresponding opening of the passage, and a second porous fabric covering at least a portion of the interior surface of the shaped-layer including the corresponding opening of the passage. A vacuum source coupled to the liner, via the valve on the socket, draws a vacuum which is wicked across the entire surface of the first and second porous fabrics which interface with the socket and the user's residual limb, respectively. The vacuum secures the socket to the liner and the liner to the residual limb of the user.
US08535387B2 Patient-specific tools and implants
A method for preparing a femoral neck for receiving a neck implant includes obtaining image data of a proximal femoral bone and femoral neck of a patient by a medical imaging method and constructing a three-dimensional image model of the proximal femoral bone and neck of the patient using the image data. The method further includes identifying a three-dimensional cortical boundary surface at an interface between cortical and cancellous bone of the patient using the image model. A patient-specific broach having a three-dimensional cutting surface closely matching and complementary to the cortical boundary surface of the patient using the image model is designed and manufactured.
US08535385B2 Prosthetic implant support structure
A prosthetic system that includes a prosthetic implant and a support structure secured to an inner surface of the cavity in the end of the bone is disclosed. The support structure defines a channel that extends through the length of the support structure. The prosthetic implant is received in the channel, and a portion of the prosthetic implant is secured to an inner surface of the channel by an adhesive. The stem of the prosthesis beyond the channel may be cemented or uncemented. The support structure may have an approximately funnel shape. The support structure may be a hollow porous cylindrical sleeve. The support structure may comprise a pair of partially hemispherical components arranged in spaced apart relationship thereby defining a channel between the pair of components. The support structure may comprise a plurality of pedestals secured to the inner surface of the cavity of the bone.
US08535383B2 Systems and methods for compartmental replacement in a knee
A kit for a prosthesis system includes a plurality of first components, each of the plurality of first components for replacing one of a plurality of first surface portions of a bone, a second component for replacing a second surface portion of the bone and a resilient connector for connecting at least one of the plurality of first components to the second component. In accordance with one method, components from a prosthesis system kit used to replace adjacent portions of a bone surface are assembled ex vivo.
US08535381B2 Catalytic surface for hydrogen release reactor
There is disclosed a gold surface for the catalytic release of hydrogen from an alkane thiol. More specifically, the present disclosure provides a large surface area of gold on a carbon fiber scaffold that does not contain any sublayers of metals that can block the catalytic release of hydrogen from alkane thiols or form other reactions that remove the sulfur moiety from alkane thiol. There is further disclosed a method for forming a gold surface onto woven carbon fiber sheets wherein no sublayer or other intermediate material is used.
US08535380B2 Fixation device and method
An implantable orthopedic stability device is disclosed. The device can have a contracted and an expanded configuration. A method of using the device between adjacent vertebral body surfaces surfaces for support and/or fixation of either or both of the adjacent vertebrae is also disclosed.
US08535375B2 Intraocular lens insertion device
An intraocular lens insertion device capable of folding an intraocular lens into a predetermined shape without giving a local stress to the intraocular lens. The intraocular lens insertion device 2 may include a lens disposing part 15 for disposing an intraocular lens 4, a slider 7 for pushing out the intraocular lens 4, a plunger 8 for further pushing out the intraocular lens pushed out by the slider 7, a transition part 31 for deforming the intraocular lens 4 pushed out by the slider and the plunger, and a nozzle 32 for ejecting out the deformed intraocular lens 4.
US08535364B2 Methods and apparati for the close application of therapeutic and other devices to the pelvic area
Embodiments of the present invention are directed to apparati and associated methods for an easy on-off device to support and provide direct therapeutic cooling relief to the affected genitalia of persons having post-operative pain and swelling.
US08535362B2 Device for conveying air to a person
The invention relates to a device for conveying heated air to a person and comprises an air-permeable inner sheet and an air-impermeable outer sheet which are connected to one another by welds in order to form a panel-like shape in the inflated state. The welds produce a main duct having, viewed at the inlet end and in the non-inflated state, a main duct width. The main duct is delimited by at least one first series of elongate first welded strips, the first intermediate spaces which are in line with one another. The length of each of these first intermediate spaces, viewed in the non-inflated state, is in each case smaller than the main duct width. The length of each first welded strip is at least 15% of the main duct width and at most 80% of the main duct width.
US08535361B2 Method and portable system for non-invasive, in-vivo blood irradiation light therapy
The present invention is a non-invasive apparatus, system, and method for performing irradiation light therapy upon blood circulating within the nostrils of a living mammalian subject. The merit and medical value of the invention resides in its ability to achieve a reversal of red blood cell aggregation in-vivo without invading the tissues or organs of the living subject—a clinical result which leads to lower blood viscosity and improved blood circulation. In this manner, the invention provides the living mammalian subject with an enhanced immunity from diseases, a reduced vulnerability to hypertension, and a reduced risk of a cardiovascular incident. Furthermore, by altering the wavelengths transmitted by the light generating unit(s) and controlling the light energy dosage, the method and system can also fine-tuned further as intervention for various diseases.
US08535360B2 Systems and methods for treating superficial venous malformations like spider veins
Systems and methods treat superficial venous malformations, such as spider veins. The systems and methods distribute a light-reactive agent, e.g., verteporfin, at or near an inner wall of a vein. The systems and methods activate the light-reactive agent by applying non-thermal light energy at a wavelength that activates the light-reactive agent to cause localize injury to the inner wall of the vein.
US08535359B2 Near infrared microbial elimination laser systems (NIMELS)
Methods, systems, and apparatus for Near Infrared Microbial Elimination Laser Systems (NIMELS) including use with medical devices are disclosed. The medical devices can be situated in vivo. Suitable medical devices include catheters, stents, artificial joints, and the like. NIMELS methods, systems, and apparatus can apply near infrared radiant energy of certain wavelengths and dosimetries capable of impairing biological contaminants without intolerable risks and/or adverse effects to biological moieties other than a targeted biological contaminant associated with traditional approaches described in the art (e.g., loss of viability, or thermolysis). Lasers including diode lasers may be used for one or more light sources. A delivery assembly can be used to deliver the optical radiation produced by the source(s) produced to an application region that can include patient tissue. Exemplary embodiments utilize light in a range of 850 nm-900 nm and/or 905 nm-945 nm at suitable NIMELS dosimetries.
US08535358B2 Bone screw and method for manufacturing the same
A bone screw and a method for manufacturing the same includes a screw thread configuration having one or more grooves cut into a leading face of the thread, a trailing face of the thread, and/or the shaft between the threads. Other implementations include the incorporation of facets into the one or more grooves. The implementation of the one or more grooves increases the surface are of the orthopedic screw and functions to increase in anchoring the bone screw within the bone once inserted therein, and thereby reduce the possibility for the screw backing out after insertion.
US08535356B2 Screw implant and system and method for locking a screw in an implant plate
A plate system and method comprising a plate and a screw having an integral resilient lock. The screw comprises a head that has a portion that is adapted to be compressible as it is screwed into bone using a tool. After the screw head is received in the plate and the tool is removed therefrom, the screw head decompresses or expands into a locking or receiving area, thereby locking the screw in the plate. The plate is adapted to have at least one or a plurality of detents or lips for cooperating with at least a portion of the screw head to retain the screw in the plate and prevent it from withdrawing therefrom.
US08535355B2 Dorsal midfoot bone plate system and method
A bone plate system for joining together adjacent bone parts of a surgical patient includes a bone plate having a first slot defining a first centerline axis, a second slot defining a second centerline axis, and a third slot defining a third centerline axis. The first, second and third slots are disposed in a triangular arrangement and simultaneously positionable over each of three adjacent bone parts. Each of a first compressing screw, a second compressing screw and a third compressing screw has a threaded shank for passage through the first, second and third slots, respectively, and engagement into the underlying bone part. Each of the first, second and third compressing screws also has a screw head configured to forcefully interact during insertion until fully seated with the first, second and third slot, respectively, thereby urging the first, second and third compressing screws to move along the first, second and third centerline axis, respectively, such that the three bone parts are multi-axially compressed towards each other.
US08535354B2 Bone plate system and methods of using the same
A bone plate locking system including a threaded screw body having a proximal end and a distal end and a plate with a through-hole. The proximal end includes a head. The head includes an upper portion, a groove adjacent the upper portion and a lower portion adjacent the groove, wherein a center-axis of the groove is off-axis to a center-axis of the threaded screw body. A locking ring configured to reside within the groove of the head. The through-hole includes an upper portion, a groove adjacent the upper portion and a lower portion adjacent the groove. The head is receivable in the through-hole. The locking ring is rotatably positioned around the groove of the head such that in an unlocked position the locking ring is outside the groove of the through-hole and in a locked position the locking ring is at least partially within the groove of the through-hole.
US08535350B2 Knotless suture anchor
A suture anchor comprises a shell and an anchor member. The shell comprises a body having a distal end, a proximal end and sidewalls therebetween defining an axial cannulation therethrough. The anchor member comprises a body having a distal end and a proximal end which is sized to fit within the cannulation. The sidewalls define a lateral cut-out such that with the anchor member received within the cannulation a first lateral portion of the anchor member is exposed laterally and a second, laterally opposite, lateral portion of the anchor member is enclosed by the sidewalls. A friction enhancement on the first lateral portion frictionally engages a bone surface when the suture anchor is disposed within a bone tunnel defined by the bone surface. Suture is trapped between the shell and the anchor and also between the anchor and the bone surface.
US08535349B2 Fistula grafts having a deflectable graft body portion
This invention provides, in certain aspects, unique devices and methods for treating fistulae. In one embodiment, an inventive device includes an elongate graft body having a proximal end and a distal end. The graft body is configurable to a first condition and a second condition, the second condition including the distal end deflected laterally relative to its position in the first condition of the body. The device also includes a tether, which is connected to the graft body, and is configured to traverse proximally along the body. The tether is manipulable to convert the graft body from the first condition to the second condition. Such a device may also include one or more additional tethers connected to the graft body. For instance, a second tether can be configured to extend distally from the distal end of the graft body, and may be effective in pulling the graft body along a fistula tract.
US08535343B2 Method for left atrial appendage occlusion
Disclosed is an occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device includes a pumpable injectable material and a retention member having a tissue penetrating shaft which extends from a proximal end of the device to a distal end of the device.
US08535341B2 Methods for ultrasonic tissue sensing and feedback
An ultrasonic surgical instrument is presented including an ultrasonic transmission member having a proximal end and a distal end, and a handle member located at the proximal end of the transmission member. The ultrasonic surgical instrument also includes an end effector assembly located at the distal end of the transmission member. The end effector assembly includes a sensing mechanism for sensing load variations on tissue based on mechanical vibrations detected on one or more portions of the surgical instrument, the mechanical vibrations sensed by a laser interferometer.
US08535340B2 Methods for ultrasonic tissue sensing and feedback
An ultrasonic surgical instrument is presented including an ultrasonic transmission member having a proximal end and a distal end, and a handle member located at the proximal end of the transmission member. The ultrasonic surgical instrument also includes an end effector assembly located at the distal end of the transmission member. The end effector assembly includes a sensing mechanism for sensing load variations on tissue based on mechanical vibrations detected on one or more portions of the surgical instrument, the mechanical vibrations sensed by a laser interferometer.
US08535337B2 Pedicle screw insertion system and method
Improved methods and apparatuses for inserting pedicle screws in accordance with embodiments of the present invention include an image correction algorithm. In various embodiments, an original image of a region of interest of a patient including a pedicle is created with an X-ray emitter and an X-ray detector. Due to the X-ray emitter not being aligned orthogonal to the X-ray detector, the original image will be skewed. Using a known location and orientation of the X-ray detector, a location and orientation of the X-ray emitter provided by a position monitoring system, and the original image, a processing system can execute the image correction algorithm to provide a corrected image to allow a surgeon to properly insert a pedicle screw along the axis of the pedicle while viewing an accurate corrected image in real time.
US08535335B2 Needle-coupled parallel mechanism
A needle-coupled parallel mechanism is provided. The needle-coupled parallel mechanism is structurally improved so as to have a broad working area and a high precision. The needle-coupled parallel mechanism comprises a fixedly positioned frame, a main shaft, three first links, three second links, and a needle. The main shaft is arranged so as to be movable relative to the frame. One end of each of the first links is connected to the frame between both ends of the main shaft and the other end thereof is connected to one end of the main shaft. One end of each of the second links is connected to the frame between both ends of the main shaft and the other end thereof is connected to the other end of the main shaft. The needle is linearly movably coupled to the main shaft to perform a predetermined operation on a target object. Each of the first links and the second links has at least three joints selected from a prismatic joint, a 1-axis revolute joint, a 2-axis revolute joint and a spherical joint. The needle and the main shaft are moved with 6 degrees-of-freedom in conjunction with the operations of the first links and the second links.
US08535332B2 Two stage plunger for intraocular lens injector
A plunger for an IOL injector device includes a shaft with a distal tip and a compressible sleeve positioned about the shaft with the tip extending forwardly of the sleeve. In a first stage of IOL advancement through the injector device, the plunger tip engages and pushes the IOL through a first section of the injector body. In a second stage of IOL advancement, the sleeve enters the narrowing section of the injector body toward the open tip thereof with the IOL and sleeve both undergoing compression. The sleeve compresses and lengthens in a forward direction ultimately enveloping the plunger distal tip. Viscoelastic applied inside the injector accumulates between the leading edge of the compressed sleeve and the compressed IOL thereby creating hydraulic pressure which pushes the compressed IOL through the remainder of the injector body and out the open distal tip thereof.
US08535331B2 IOL injector
A device for injecting an intraocular lens (IOL) into an eye, the device having an injector body including a lumen and an open tip wherethrough the IOL is expressed from the device. An IOL loading bay is located in the passageway wherein the IOL is positioned and compressed. The injector tip is dimensioned to allow the surgeon to choose an insertion depth between first, second and third transition points defined on the tip, the first and second transition points having a larger diameter than the third transition point which is located closer to the open tend of the tip. If the surgeon wishes to insert through a very small incision size (e.g., about 2.4 mm), the surgeon will insert the tip only up to the third transition point. The injector is stable during delivery of the IOL therethrough due to a spreading of the tip within the eye which effectively anchors the tip during IOL delivery.
US08535329B2 Tracking tools and method for computer-assisted shoulder replacement surgery
The invention includes a method for tracking the human scapula during shoulder surgery, by a trackable device fixed to the coracoid process of the scapula. A device of the invention allows a trackable target to be fixed to the coracoid process by bone screws and an anchor. In one embodiment, a releasable coupling is provided between the anchor and the trackable target.
US08535323B2 Constraining ring inserter
A hand held instrument is provided in one embodiment in a kit for use in positioning a constraining ring of an acetabular liner system and includes a shaft including a first coupling member, and a plurality of heads, each of the plurality of heads including (i) a base configured to couple with the first coupling member and (ii) a pair of resilient gripper arms, each of the pair of resilient gripper arms defining a constraining ring reception area having a size different from the constraining ring reception area defined by the pair of gripper arms of each of the other of the plurality of heads.
US08535320B2 Method and apparatus for performing spinal surgery
Instruments and methods for creating an operative corridor to the spine are described. The instruments include, for example, a retractor assembly with at least one retractor blade that may be releasably coupled to a bone anchors via a hoop shim. The hoop shim includes a shim portion that may slidably engage the retractor blade and a hoop portion extending from the shim portion that includes an aperture that receives the bone anchor. The hoop portion may have an unlocked configuration that allows passage of the bone anchor and a locked position which prevents passage of the bone anchor to releasably couple the hoop shim to the bone anchor. The hoop shim may be configured to couple to the bone anchor such that the hoop shim may angulate relative to the bone anchor.
US08535315B2 Apparatus and method for cutting costal cartilage
A double-bladed cutting device providing a practical method for obtaining costal cartilage specimens in both an operating room and research setting. The device reduces the skill and time required to fashion cartilage slices, while increasing the uniformity of the cut specimens. Furthermore, via an adjustable guide, slices can be obtained precisely from the central core of the rib. Although specimen lengths up to 4 cm are preferred, longer lengths can be attained without modification of the device. The cartilage specimen may be held in place within the device via means of compression or tension.
US08535314B2 Surgical connecting element for fixing adjacently arranged bone plates
In order to configure, in such a way as to be capable of being employed in a simple and secure manner and produced cost-effectively, a surgical connecting element for fixing adjacently arranged bone plates, comprising a first bearing element, a second bearing element and a coupling element, by means of which the first and second bearing element can be coupled to each other in such a way that bone plates lying between the first and second bearing element can be fixed, it is proposed that the second bearing element and the coupling element be so designed and adapted to each other that, by relative movement between the coupling element and the second bearing element transversely to a clamping direction, the bone plates are fixable between the first and the second bearing element.
US08535312B2 Apparatus, system and method for performing an electrosurgical procedure
An electrosurgical apparatus includes a housing having at least one shaft extending therefrom that defines a longitudinal axis therethrough. The shaft operatively supports an end effector assembly at a distal end thereof. The end effector assembly includes first and second jaw members pivotably connected to each other and moveable from an open spaced apart position to a closed position to grasp tissue. An electrically conductive tissue sealing plate is operatively coupled to each of the jaw members. At least one of the jaw members has a serrated edge disposed thereon for selectively sectioning tissue upon rotation of the end effector assembly about the longitudinal axis. The electrically conductive tissue sealing plates are adapted to connect to an electrosurgical energy source. The electrosurgical apparatus operably communicates with a control system configured to regulate the delivery of electrosurgical energy from the source of electrosurgical energy to the electrically conductive tissue sealing plate on each of the jaw members.
US08535296B2 Apparatus for aspirating, irrigating and cleansing wounds
An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. microfiltration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.
US08535295B2 Protective cover
A protective cover for a site on a patient is provided which provides an effective moisture barrier to the site. The cover includes a first, absorptive layer which absorbs and wicks away any accumulated moisture on the site to keep the site dry and contaminant free, and a second, waterproof layer which precludes penetration of moisture and other such external effects to keep both the first layer and the site dry. Cuffs formed on open end portions of the second layer direct water and other such contaminants away from potential points of entry, thereby providing a further level of protection to the first layer and the site.
US08535294B2 Carotid sheath with flexible distal section
The present invention is a carotid sheath that has a proximal portion that is stiffer than the distal portion of the sheath as a result of the proximal portion having a higher durometer of the outer plastic coating of the sheath's proximal portion with a lower durometer for the plastic coating on the more flexible distal portion of the sheath. Another means to increase the flexibility of the sheath's distal portion compared to a stiffer proximal portion is by having a slightly smaller outside diameter for the outer plastic coating of the distal portion of the sheath. A more flexible distal portion of the sheath allows easier access for angiography, angioplasty or stenting when the sheath is used to access the tortuous path encountered when entering the carotid arteries.
US08535291B1 Guided delivery of cell, particle, and drug based therapies
A medical practitioner can specify certain parameters for a procedure that involves delivering a therapeutic agent, while leaving other parameters open. The therapeutic agent can be sensitive to biomechanical forces (or other influences) associated with delivery. The procedure can involve regenerative medicine, for example delivering progenitor or stem cells to a diseased heart using a catheter, whereby unbridled transport in the catheter may compromise efficacy. The open parameters can influence efficacy of the agent and thus therapeutic outcome. A computer-based system can apply stored information, such as from databases, to narrow the possible values of the open parameters. From the narrowed possibilities, an optimization routine can determine suitable or optimized values for the open parameters. The determined values can manage biomechanical forces incurred by the therapeutic agent, thereby promoting efficacy and healing. The optimized parameters can guide the practitioner in the procedure.
US08535290B2 Apparatus and methods for clot dissolution
Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
US08535287B2 Magnetizable tampon device
In a tampon device for introduction into the female vulva, comprising a packing material of absorbent material for the absorbance of menstrual fluid, menstrual pains such as painful myogeloses and cramps in the region of the vaginal musculature are alleviated or stopped in that the packing material incorporates a magnetic substance that interacts with the earth's magnetic field.
US08535283B2 System and method for applying reduced pressure at a tissue site
The illustrative embodiments described herein are directed to a manually-actuated pump and method for applying reduced pressure at a tissue site. The manually-actuated pump includes at least one variable volume chamber that is manually compressible into a plurality of positions. The manually-actuated pump includes a fixed volume chamber in communication with the at least one variable volume chamber. The manually-actuated pump also includes a filter housing having a hydrophobic filter that prevents liquid from entering the at least one variable volume chamber. The fixed volume chamber is coupled to the at least one variable volume chamber via the filter housing. The filter housing is located in between the at least one variable volume chamber and the fixed volume chamber. The fixed volume chamber has reduced pressure that is applied to the tissue site in response to a movement of the at least one variable volume chamber from a compressed position in the plurality of positions to an uncompressed position in the plurality of positions.
US08535281B2 Portal with septum embedded indicia
An implantable portal includes a septum that has embedded therein an indicia adapted to identify at least one characteristic of the portal. The indicia may be formed as an impression at a base layer of the septum, and is filled with a radiopaque material. The septum base layer is covered by liquid silicone, which bonds with the septum base layer when solidified, so that an integral one-piece septum, with the identifier indicia embedded therein, is effected. The indicia embedded septum is fitted to the reservoir housing of the portal for providing identification information for that portal. The septum embedded indicia is viewable visually and also by x-ray or computer tomography imaging.
US08535280B2 Pressure based refill status monitor for implantable pumps
The present invention includes systems and methods for detecting fluid flow into or out of a port chamber or a reservoir of an implantable medical device utilizing a pressure sensor. The system detects characteristic pressure profiles associated with fluid flowing into the medical device, out of the medical device, and also whether one or both of the port chamber or reservoir are substantially empty or substantially full. In addition, the present invention may generate a sensory cue to a clinician to indicate the fluid status.
US08535276B2 Syringe-attached topical anesthetic dispenser
A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A pair of clips receive a barrel of the syringe. The clips are on a housing receiving a pre-filled cannister of a topical numbing agent and including a chamber. The cannister includes an aerosol dispensing valve actuated by a button which when pressed moves the cannister with respect to an actuator for the valve.
US08535275B2 Syringe-attached topical anesthetic dispenser
A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A clip receives a barrel of the syringe. The clip includes a receptacle portion receiving a pre-filled cannister of a topical numbing agent, wherein the cannister includes a generally cylindrical chamber portion receivable within the receptacle portion of the clip and a distal neck portion having an outlet allowing contents of the cannister to be dispensed. A dispenser attached to the distal neck portion of the cannister includes an elongated flexible tube surrounded by a rigid tube for at least a portion of a length of the elongated flexible tube. A pivotable lever carries a tube compressor including a pinching member extending through an opening in the rigid tube and spring biased to a position at which the pinching member pinches closed an elongated passageway through the flexible tube. The pivotable lever is spring biased to the position at which the flexible tube is pinched closed and is pivoted against the spring bias to open the flexible tube and dispense the numbing agent.
US08535270B2 Trocar entry incorporating an airbag
A safety trocar assembly incorporating an airbag is provided to prevent overpenetration of the safety trocar assembly through an abdominal wall and into a body cavity. The safety trocar assembly includes an airbag cannula having an expandable airbag proximal of the distal end of the cannula. A sensing device is located at a distal end of the cannula for detecting changes in conditions at the distal end of the cannula. A trigger mechanism is provided on the cannula and operates to inflate the airbag in response to a change in condition detected by the sensing device.
US08535268B2 Device for at least one of injection or aspiration
Devices, systems, and associated methods that facilitate the injection and/or aspiration of precisely controlled volumes of fluids at precisely controlled rates are provided. In some implementations, an apparatus may include a syringe and a lead screw connected to a plunger of the syringe. A ratchet gear may be connected to the lead screw. A mechanism may also be included to oscillate a frame in a direction perpendicular to a longitudinal axis of the lead screw such that one or more pawls of the frame engage the teeth of the ratchet gear in a manner that results in rotation of the ratchet gear in a single direction for controlled linear displacement of the plunger.
US08535262B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control
A method for achieving tight glycemic control in a patient in need thereof is disclosed. The method comprises deploying an equilibrium glucose sensor within a blood vessel in the patient, coupling the sensor to a monitor that displays the blood glucose concentration, and administering a blood glucose regulator when the blood glucose concentration varies outside of the predetermined concentration range. The blood glucose regulator is administered in an amount sufficient to return the blood glucose concentration to within the predetermined concentration range, thereby achieving tight glycemic control.
US08535260B2 Devices, systems, and methods for localized drug delivery
Devices, systems, and methods for localized drug delivery. In at least one embodiment of a method of localized drug delivery, the method comprises the steps of placing a resorbable device within a tube, introducing the tube within a mammalian body at or near a tissue and/or organ within the mammalian body, and anchoring the resorbable device to the tissue and/or organ. Devices and systems useful for performing such a method are also disclosed herein, wherein an exemplary device comprises at least one drug release portion having at least one drug to be released over time and a binder intermixed with the at least one drug, and at least one resorbable anchor portion coupled to the at least one drug release portion.
US08535257B1 Syringe and swab system
The current invention is a syringe and swab system for a syringe having a plunger, a barrel, a needle hub, a needle, a needle safety cover, and a swab attached to the distal end of the needle safety cover for placing over an injection site to apply pressure.
US08535254B2 Lumbar traction device
A lumbar traction device is herein disclosed. The lumbar traction device includes a lumbar support member to be worn adjacent to a lumbar region of a user, at least one lower leg support to be worn adjacent to a lower leg of the user, and at least one connecting member connecting the lumbar support member and the at least one lower leg support, the at least one connecting member being substantially inelastic. When a load is applied to the at least one lower leg support, the load is transferred to the lumbar support member via the at least one connecting member. When the load is transferred to the lumbar support member, the lumbar support member forcibly presses against the lower lumbar area of user, thereby distracting the hip bone from the lower vertebrae.
US08535253B2 Tubeless compression device
A compression device for applying compression to a body part of a wearer has an inflatable bladder defined by first and second bladder layers and a bladder sealing line securing the first and second bladder layers to one another. A conduit is defined by spaced apart, generally opposing conduit sealing lines securing the first and second bladder layers to one another and portions of the first and second bladder layers between the conduit lines. The conduit is fluidly connected to the inflatable bladder for delivering pressurized air to the inflatable bladder. Tubing is not needed for connection to the compression device.
US08535251B1 Mechanical device to assist in the external compression of the chest during cardio-pulmonary resuscitation
A portable mechanical device to assist in external chest compressions during cardio-pulmonary resuscitative procedures. The embodiment consists of a frame (100), a plunger unit (104) and an articulating lever (109). The bottom member (102) of the frame is positioned under the subject such that the dome of the plunger unit (104) rests above the mid-sternal region. The handle (108) at the free end of the lever is used to apply downward force by the life-saver to provide the necessary chest compressions. The device is light in weight, easily transportable, and has an indefinite shelf life. This device is designed to be used by anyone with a basic training in CPR. The portability of the device renders itself useful outside the environs of a hospital, in confined quarters, and at remote locations.
US08535244B2 Guidewire and method of insertion of same
This invention provides a guidewire adapted for the catheterization of very small vasculature of the neonates, infants and children. In one embodiment of the invention, a guidewire of 0.010 inch diameter is described. The present invention also provides an alignment adaptor that facilitates catheterization of small vasculature utilizing said guidewire, and method of using the same.
US08535243B2 Medical devices and tapered tubular members for use in medical devices
Medical devices and methods for making and using the same. An example medical device may include a metallic tubular member including a tube wall defining an inner diameter and having a wall thickness. The tubular member may have a plurality of slots formed therein. The tubular member may also include first portion having a first length. The tube wall may have a substantially constant wall thickness across the first length. The tubular member may also include a second portion having a second length. The tube wall may thin so that the inner diameter increases across the second length.
US08535241B2 Fluid diversion mechanism for bodily-fluid sampling
An apparatus includes a housing, a flow control mechanism, and an actuator. At least a portion of the flow control mechanism is movably disposed within the housing. The apparatus further includes an inlet port and an outlet port, and defines a fluid reservoir. The outlet port is fluidically coupled to a second fluid reservoir and is fluidically isolated from the first fluid reservoir. The actuator is configured to move the flow control mechanism between a first configuration, in which the inlet port is placed in fluid communication with the fluid reservoir such that the fluid reservoir receives a first flow of bodily-fluid, and a second configuration, in which the inlet port is placed in fluid communication with the outlet port.
US08535239B2 Tissue harvesting device with manual dicing mechanism
A dicing device dices tissue harvested from a patient. The dicing device comprises a grid cutting element and a tray to receive diced tissue. The dicing device may be integrated into an otherwise conventional biopsy device. The diced tissue specimens may be further processed, such as by being introduced into a self-expanding fistula plug creation and delivery system. The self-expanding fistula plug creation and delivery system comprises a sheet and a reinforcement tube. A scaffold material may be placed in the sheet, which may then be folded and reinforced, with the scaffold material being compressed in the sheet. The scaffold material may then be pushed into a catheter end. The catheter end may be inserted in a fistula. The scaffold material may then be flushed with a cell matrix that is based on the diced tissue to create a fistula plug, which may be left in the fistula.
US08535234B2 Apparatus for measuring blood volume and method of evaluating result of measurement by apparatus for measuring blood volume
An apparatus for measuring a blood volume, includes: a first calculator which calculates a first blood volume by using information on a cardiac output of a subject; and a second calculator which calculates a second blood volume by using information on oxygen metabolism of the subject.
US08535232B2 Real time ultrasound catheter probe
An ultrasound catheter probe assembly capable of scanning a three-dimensional volume is provided. The ultrasound catheter probe assembly contains a plurality of ultrasonic transducers disposed along a central axis of the ultrasound catheter probe assembly. The plurality of ultrasonic transducers is disposed on a mechanism operable to reciprocally pivot the plurality of ultrasonic transducers enabling the plurality of ultrasonic transducers to scan a three-dimensional volume. A helically disposed electrical interconnection member may be disposed about a pivot axis of the plurality of ultrasonic transducers and may electrically interconnect the plurality of ultrasonic transducers to an ultrasound imaging system. The ultrasound transducer catheter probe assembly may be fluid-filled and contain bubble position control and fluid expansion compensation features.
US08535230B2 Ultrasound device
An ultrasound device is provided. The ultrasound device includes an ultrasound transducer to be moved along an object to be examined and a control device that communicates with the ultrasound device, controls the transmit and receive mode of the ultrasound transducer and processes the ultrasound signals received. The ultrasound transducer is arranged on a robotic arm that can be freely moved in space and controlled in terms of its movement.
US08535225B2 Integrated colligation evaluating device for human body enginery indexes
An integrated colligation evaluating device for human body enginery indexes and the working method thereof. The device includes an equipment case (1) provided with a plurality of measuring sensors. A circuit board (13) which is electrically connected with a power source (2) is arranged in the equipment case (1). The circuit board (13) has a plurality of signal processing modules which are electrically connected with a CPU controller (14). Multiple measuring sensors can respectively transfer the human body plural enginery index signals to electrical signals, which are subsequently processed and analyzed by the signal processing modules. The processed electric signals are transmitted to the CPU controller (14) for analyzing and colligation evaluating, or displaying by a terminal displayer (6), or transmitting the human body plural enginery indexes and the human body healthy evaluation results to a master computer for preserving and processing through data transfer interfaces (15), forming and printing reports. The working method includes receiving and processing the human body plural enginery index signals, and conducting colligation evaluating.
US08535224B2 Electro diagnostic functional assessment unit (EFA-2)
An electro diagnostic functional assessment unit (EFA-2) that diagnoses age of and treats soft tissue injuries. The EFA-2 utilizes sensor(s) including EMG, Range of Motion, FCE, pinch and grip, and allows for monitoring of muscles and muscle groups to ascertain compliance, pain and function. The EFA-2 also monitors disc pathology and determines whether a person requires surgery or conservative care and, the age of the disc. Additionally, the EFA-2 monitors EEK activity and NCV, as well as invasive EMG that monitors nerve damage. Previously, with NCV the temperature and the position of electrodes would effect readings and produce false positive or false negative readings. The EFA-2 eliminates these problems by incorporating temperature sensor(s) and electrode placement sensor(s). The EFA-2 also provides direct treatment by means of ultrasound and electrical stimulation. Thus, the EFA-2 allows diagnosis any treatment by means of a single unit.
US08535223B2 Wireless patient monitoring using streaming of medical data with body-coupled communication
The invention relates to a system and method for wirelessly monitoring a patient (4), the system comprising a medical sensor (1) for collecting medical data and a coupling interface (2) for coupling with a monitor (3). The medical sensor (1) is attached to the patient's (4) body, and the medical data collected by the medical sensor (1) is transmitted to the coupling interface (2) via body-coupled communication (5). Preferably, the collected medical data is streamed to the coupling interface (2) via body-coupled communication (5). This way, a secure and reliable system and method for wireless patient monitoring are achieved which only require little power.
US08535219B2 Fluid manifold for endoscope system
A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories.
US08535216B2 Pelvic floor repair system
Systems, method, and devices related to surgically implantable supportive slings are presented herein. More specifically, in various embodiments, the systems, devices and methods relate to a surgically implantable supportive sling adapted to anchor in patient tissue.
US08535205B2 Hand therapy exercise tools, and methods of constructing and utilizing same
A multi-functional group of hand/forearm exercise tools wherein each tool permits the user to strengthen one or more muscles associated with the hand/forearm of the user, and/or to increase radial and ulnar deviation and forearm pronation and supination, or permits the user to mimic a functional task, such as turning a door knob, opening a bottle cap, inserting and turning a key, turning and tightening a nut, and turning and tightening a bolt.
US08535204B2 Exercise apparatus
A doorway exercise apparatus is described. In one implementation, there is provided an apparatus comprising two elongate handle struts spaced apart by a distance between shoulder width and doorway width, each handle strut having a longitudinal axis, the strut axes being substantially in a single plane; an elongate rest member having a longitudinal axis transverse to the strut axes, the elongate rest member comprising two rest surfaces spaced greater than a doorway width apart in a single plane; two elongate spaced-apart drop members each drop member having a longitudinal axis, each drop member axis substantially perpendicular to the rest member; and releasable attachment means from which the drop members depend; wherein the handle struts extend about one cubit away from the rest member in a direction opposite the rest surface.
US08535202B2 Method and device for operating a hybrid drive of a vehicle
A method and a device for operating a hybrid drive of a vehicle includes a parallel hybrid drive train having an internal combustion engine, at least one electric machine, a shift element interposed between the internal combustion engine and the electrical machine, a automatic transmission, and a power take-off. The internal combustion engine is frictionally connected to the electrical machine via the shift element and may be started by the electric machine. A coordinated sequence of functions with defined intermediate states is called up. A state of the shift element for the synchronization of a transmission input of the transmission to a target transmission input speed is varied once the engine has been started. The synchronization is performed either purely with an electromotive force or with a force produced by a combination of the electrical machine and the internal combustion engine.
US08535201B2 Method and strategy to detect the lock-up of planetary gear in power split hybrid vehicles
A system and method for controlling a hybrid electric vehicle powertrain having an engine, a generator, and a motor connected via a planetary gear set to detect lockup in the planetary gear set and control the powertrain in response. When torque is distributed in an electric mode of operation with the engine disabled, the generator is disabled based at least upon a difference between actual generator speed and an expected generator speed exceeding a threshold, indicating a lockup in the planetary gear set. When the engine is activated and distributes torque through the powertrain, the engine and the generator are disabled based at least upon a difference between engine acceleration and an expected engine acceleration exceeding a first threshold, and a difference between engine speed and ring gear speed being less than a second threshold.
US08535197B2 Speed changer assembly
A speed changer assembly for changing the rotational speed of an engine's (or other prime mover's) output to that required by the input of a process machine. In operation, a first gear is in meshing engagement with an idler gear, which in turn, is in meshing engagement with a second gear. When operation of the speed changer assembly is halted, the idler gear is pivotable about one of the first and second gears. A center distance between the idler gear and the gear about which the idler gear is pivoted remains constant while the center distance between the idler gear and the other gear is varied. The idler gear is taken out of meshing engagement with the other gear, permitting replacement of said other gear. The idler gear is then pivoted to establish meshing engagement with the replacement gear and the speed changer is configured with a new speed ratio.
US08535191B1 Aluminum flange with anti-rotation slots
A differential flange assembly is disclosed herein that includes a flange member and a washer member. The flange member is defined by an engagement face and having an aperture therethrough. At least one slot is formed on the engagement face so as to extend radially outward from the aperture. The washer member has at least one tab extending from a peripheral edge of the washer member and at least one opening. The tab is configured to be seated within the slot to mate the washer member to the engagement face of the flange member. The interaction of the slot of the flange member and the tab of the washer member prevent rotation of the washer member with respect to the flange member.
US08535190B2 Transmission device with power splitting
A transmission with power branching, and the transmission, in a first drive range, transmits torque from the ring gear to a fixed wheel. In one branch, power is transmitted from a first to a second hydraulic unit which respectively operate as a pump and a motor. At one of the hydrostatic shafts, the mechanical and hydrostatic power are summed and transmitted to the drive output. In a second drive range, power coming from the planetary carrier is partially branched off to the ring gear and transmitted, via the gear wheels of the hydrostatic shaft, to the second hydraulic unit. From the second hydraulic unit, hydraulic power passes to the first hydraulic unit. In the process, the first hydraulic unit operates as a motor and the second hydraulic unit as a pump. From the second sun gear, power is transmitted to the double planetary gear and summed.
US08535185B2 Acquiring and providing player information by means of a multiple sensor system
A device (120) for acquiring and providing information which can be associated with a football player, said device comprising: an acceleration sensor (129) for detecting accelerations acting on the devices; a memory unit (121) for storing measured acceleration values with associated time stamps and an ID associated with the device (120); and a radio unit (128) for receiving a first radio signal (150) with a first time stamp, wherein the first radio signal represents a deformation of a ball, and for transmitting a second radio signal (160) including the ID associated with the device (120) in case that a check of the values in the memory unit shows that an acceleration was detected by the device at the corresponding time.
US08535184B2 System and method for a removable wheel device
A removable wheel device which slides onto the base of a sports field goal. The wheel device allows one person to move a goal across a field without using excessive force by sliding one wheel device onto the base of each goalpost and using leverage to tilt the goal and push or pull it for a distance. When inserted onto the base of the goal, the wheel device does not require any type of fastening to remain in place, but rather uses its own unique shape to hold onto the goal. In one embodiment the removable wheel device comprises a wheel, a bracket, and a U-shaped sleeve which may slide onto the base of a lacrosse goalpost.
US08535181B2 Football sled with blocker pad range of motion
A range of motion assembly for a blocking sled includes a pivot assembly to provide a range of motion and a cartridge system to restrict the range of motion.
US08535180B1 Method and apparatus for analyzing a pitched ball
Analysis of pitches to determine both their velocity and the location at which they arrive at the batter. The speed of the pitch is adjusted according to an adjustment value whose magnitude is a function of the location of the pitch relative to the batter. For example, high outside pitches would have a different adjustment value than low inside pitches. These adjustment values are calculated to take into account the fact that hitters must swing at different pitches at different times. That is, they must swing at some pitches earlier than others, depending on the location of the pitch. The adjusted speed, or “effective velocity,” of the pitch is thus a function of both the pitch's velocity and its location relative to the batter, making it a more useful metric than velocity or location alone.
US08535178B2 Batting tee system for bat-and-ball games
A batting tee system includes a batting tee assembly that may be used with conventional balls or with the ball described as an embodiment of the present invention. Optionally, the batting tee assembly may be used with a netting system or target that provides feedback to a batter based on a trajectory of the ball after it has been struck by a bat and leaves the batting tee assembly. In one embodiment, the batting tee assembly includes a support base coupled to a swing arm, which in turn is coupled to an adjustable-height batting tee. A flexible cup may be coupled to the batting tee to eliminate or substantially reduce the bounce back or recoil felt by a batter when hitting off a batting tee. The batting tee system may be configured for both left and right handed batters and also placed in a portable or storable configuration.
US08535176B2 Golf club set
Golf club irons having improved forgiveness, playability and performance characteristics are disclosed. The embodiments set forth parameters of various irons that affect performance either alone or in combination with other parameters when the irons are utilized to strike a golf ball. The parameters, which in some cases may be systematically progressed or varied, include golf club shaft length, striking face area, loft, coefficient of restitution, face thickness, topline thickness, swing weight, sole width at the heel and toe, and other performance characteristics.
US08535173B2 Golf club with improved performance
A golf club head with an improved Moment of Inertia (MOI) is disclosed herein. More specifically, the present invention relates to a golf club head with a releasable hosel mechanism that is leaner and more lightweight, it allows a significant amount of weight to be saved from the hosel portion of the golf club head and used to improve Center of Gravity (CG) location of the golf club head; which contributes to the improvement of the MOI of the golf club head.
US08535171B2 Clubhead with external hosel
A golf club head consisting of a striking face, a soleplate, a crown, and a skirt connecting the face, the soleplate and the crown. A flange is placed at a selected location on the periphery of the skirt. Incorporated into the flange is a hosel, positioned to be displaced from the club head, for receiving the shaft of the golf club. The area of the skirt covered by the flange has a length versus height ratio.
US08535169B2 Golf ball with indicia to indicate imparted shear force
A golf ball includes an inner layer, an outer layer, and a cavity therebetween. A fluid, such as a viscous damping fluid, is placed in the cavity. When the ball is struck, the inner and outer layers rotate independently of one another. Indicia are provided on the inner and outer layers. An examination of the relative position of the indicia before the ball is struck and after the ball is struck can yield data that indicate the shear force of the stroke.
US08535163B2 Low-friction synchronous interaction in multiplayer online game
Methods for low-friction synchronous interaction in multiplayer online games are presented. In one method, a social grid with relationship information is accessed, and a first and a second game boards are executed for a first and a second user, respectively. The first and second boards are managed by the first and the second users, respectively, the social grid including a social link between the first and second users. An assistance request, generated in the second game board, is presented in the first game board. Upon detection of an acceptance of the request by the first user, an animation is generated in the second game board presenting an image sequence appearing as a first-user action in the second game board that completes at least one task associated with the request for assistance, where the action occurs without the first user accessing the second game board.
US08535162B2 Methods and systems for providing a challenge user interface for an enterprise social network
A method for providing a challenge user interface for an enterprise social network including users associated with an entity. The method can include receiving a request for a challenge leader board of users of the enterprise social network in response to a challenge being selected from a list of displayed challenges with the selected challenge having an associated point category. The challenge leader board can be based on users awarding challenge points to other users for challenges in the same point category as the point category of the selected challenge. In response to the request, challenge leader board information comprising an ordered list of users based on an amount of challenge points each user has been awarded in challenges in the same point category as the point category of the selected challenge can be obtained. The challenge leader board information can be transmitted to the user system for display.
US08535158B2 Networked gaming system communication protocols and methods
A system, method and apparatus for a gaming system is provided. The gaming system includes a rewards server and a separate gaming or slot accounting server. The system may further include a separate player tracking server. The system further includes one or more game machines. The game machines may include a base game, rewards tracking module, and a game management module. Further details will be apparent from the description, drawings and claims.
US08535150B2 System for implementing loss limits
A loss limit system and method automatically tracks a player's entry and cash play, and does not allow them to play more than an allotted dollar amount during a given time frame or lose more than the established limit. Typically, excursions of play sessions are set up by day. Play is tracked at gaming machines and locked from all other play during card in at a machine. No other play is allowed at gaming machines, auto table rating systems or open table ratings, purchase of tokens, unless buy-in has not reached the loss limit for the session. At rollover, players are allowed to play again until they meet the same criteria for loss limit.
US08535149B2 Tracking career progression based on user activities
A method for generating career progression information for a user participating in one or more activities in a processing device is disclosed. User progress in the activities is tracked. The activities include game activities and non-game activities. Achievement scores for the user based on the game activities and the non-game activities are determined The achievement scores are aggregated across the game activities and the non-game activities to generate an aggregated career score for the user. Career progression information is generated for the user, based on the aggregated career score.
US08535148B2 Wagering game device with a multiple-progressive wheel game
A method and gaming machine are disclosed for operating a game with a primary and embedded game. An embedded game is disclosed as a bonus game with one embodiment animating miniature reels inside the primary game symbol. Each embedded slot game may have its own progressive, or may be tied into the progress associated with the primary game. Each embedded slot game will have its own paytable, and may be a miniature version of a well-recognized full-sized slot game. Also disclosed are a wagering game, a gaming machine and a networked gaming system and associated methods including a multiple-progressive wheel game. A player may win all of a set of wheel-based progressive award during play of a single game.
US08535147B2 Gaming system having progressive jackpots flexibly linked with common progressive pool
A gaming system includes at least one memory device storing instructions that, when executed by at least one processor, cause the gaming system to receive wagers in response to inputs via at least one input device, and increment one or more first progressive jackpots by respective individual increment amounts totaling a total increment amount. One or more second progressive jackpots are incremented by respective individual increment amounts totaling the total increment amount, the total increment amount being based on the received wagers. In response to a triggering event awarding at least one of the first progressive jackpots, the awarded first progressive jackpot is reset to its reset value and the individual increment amount for the awarded first progressive jackpot is deducted from at least one of the second progressive jackpots.
US08535146B2 Random payout system and method for gaming devices
A random payout system provides self-funding winning symbol combinations that allow various wagering games to be quickly and easily defined. The winning symbol combinations may individually be associated with a funding pool. Symbols from a winning symbol combination may be disabled or not presented when an associated funding pool is negative. The symbols may be activated or presented when the associated funding pool is non-negative. In this manner, the winning symbol combinations are self-funding. In this manner, a gaming establishment may provide profitable games that may be easily modified to include a wide variety of winning symbol combinations. The random payout system may be used with various base and bonus games.
US08535145B2 Method and apparatus for gaming with alternate value payouts
Systems and methods are provided for permitting a player to play a game at a gaming device. The gaming device provides a payout for the game. The payout is redeemable for one of a plurality of values, and at least two of the plurality of values are different from each other. The values typically have different corresponding forms of payout, such as cash or merchandise credits.
US08535144B2 Systems and methods for fixed-odds based gaming activities
Described herein are various systems and methods for providing gaming activities. These particularly relate to “fixed-odds” type gaming activities whereby a player places a bet in relation to an event outcome on the basis of a payout ratio and, in the case that the event outcome is identified as a winning outcome, the player is awarded a prize based on the entry fee and the payout ratio. In overview, the present embodiments focus on situations wherein the player is additionally eligible to receive a secondary prize that is indeterminate at the point in time the bet is placed. The nature and purpose of this secondary prize varies between embodiments. For example, in some embodiments the secondary prize effectively provides a winning player with a more advantageous payout ratio, in some embodiments the secondary prize allows the player to participate in a secondary game.
US08535142B2 Wagering game with game appearance changing based on player's selection
A method of conducting a wagering game on a gaming terminal for a player includes receiving, via an input device, a player selection of one of a plurality of player selectable elements. Each of the player selectable elements are associated with a corresponding thematic indicia set. The method further includes conducting the wagering game with the thematic indicia set associated with the selected player selectable element being displayed on a display of the gaming terminal and while conducting the wagering game, triggering a bonus event. The method further includes awarding one of a plurality of game enhancement parameters to the player during the bonus event. The awarded one of the plurality of game enhancement parameters is dictated by the selected player selectable element.
US08535136B2 Read and write playing care
A read and write playing card is described. The playing card includes a unique card identification that uniquely identifies the playing card from other cards in the deck of playing cards. Additionally, the read and write playing card includes at least one playing card electronic component that receives data regarding game play. Furthermore, the read and write playing card includes at least one of the playing card electronic component stores data regarding game play. Further still, the read and write playing card includes at least one of the playing card electronic components transmits the unique card identification data, when activated by the electronic system.
US08535135B2 Gaming system, gaming device, and method for providing a poker game with a bonus gaming session having re-draw option
A gaming system provides a bonus gaming session that is activated during a play of a five-card draw poker base game when a predetermined plurality of the first set of five cards dealt meets a predetermined criteria, for example at least four of the five cards dealt and held by the player share a common suit. When activated, the gaming system repeats plays of the game in the bonus gaming session until a winning draw poker outcome has been generated. In the bonus gaming session, the card that is not co-suited with the plurality of the held first set of cards is discarded and randomly replaced until a winning five-card hand is generated, upon which the gaming device provides an award. The gaming system provides a correspondingly larger award for a wining flush hand for each additional re-drawn fifth card required to achieve a winning five-card flush hand.
US08535133B2 Video game with controller sensing player inappropriate activity
A video game system is operable to receive user touch location information while a first user is holding a game controller and to determine a first user ID for the first user based upon the user touch location information. Thereafter, the video game system is operable to measure an instant acceleration of the game controller, to compare the instant acceleration to a first threshold value and to lock the game controller for use by the first user corresponding to the first user ID based on the comparison of the instant acceleration and the first threshold value.
US08535132B2 Game apparatus for setting a moving direction of an object in a game space according to an attitude of an input device and game program
A game apparatus includes a CPU, and the CPU sets a moving direction, that is, a position and an orientation of a moving object within a game space on the basis of angular velocity data transmitted from a first controller, that is, an attitude of a gyro sensor unit (gyro sensor). Then, when a second controller is drawn toward a near side in a state that a C button and a Z button thereof are simultaneously pressed, and the C button and the Z button are simultaneously released in that state, the moving object is shot.
US08535131B2 Method and system for an online performance service with recommendation module
A method and system to recommend performances based on the performances' excitement-level as determined from events and characteristics associated with the performance and a subscriber's preference is described herein. A subscriber's preference influences the performance type and performance characteristics that are exciting to the subscriber. Recommendations for performances can be sent to the subscriber as a link or direct connection to a location of the online performance. Recommendations of a performance preserve the excitement of the performance by not revealing the score, outcome, or any statistics or commentary that would spoil the natural buildup of excitement from watching the live performance. Performance recommendations may include a start-time and end-time for watching only the exciting portions of the performance. Recommended portions of performances can be ranked to fit within a subscriber's customizable viewing-time, so that a subscriber can view only the most exciting portions of performances that fit within a limited time-frame.
US08535128B2 Hinge assembly for supporting a fan on a roof
A buttressed hinge assembly or a flexible hinge assembly adjusts to fit a vent on a wall or a roof in order to hold a fan thereon, which fan is especially suitable for a restaurant roof or wall. The hinge assembly attaches to a roof or wall vent to hold the fan in a proper position, yet permits the fan to be easily moved for cleaning of vent and the fan.
US08535126B2 Air flow control mechanism and methods
The invention relates to a method and mechanism to control air flow through an air handling system. In one aspect, a flow control device for use in an air handling system is provided. The device includes a flow control member having segmented sliding gates, wherein the flow control member is configured to selectively control an air flow stream by moving the sliding gates into the path of the air flow stream. The device further includes a controller member configured to control the movement of the sliding gates. Furthermore, the device includes a communication member configured to send and receive signals regarding the control of the air flow stream. Additionally, the device includes a power member for supplying power to the flow control member, the controller member and the communication member. In another aspect, a method of controlling an air flow stream in an air handling system is provided.
US08535125B2 Feed unit for filling a coin module with coins
A feed unit for filling a coin module with coins improved in such a way that a plurality of coin modules can be filled or loaded with just one feed unit. The coin feed unit is a coin drum which is rotatable inside a shell. A coin stock compartment is provided into which coins can be filled via a charge aperture. A dispensing compartment is provided inside the coin drum from which coins can be taken out via the discharge aperture. A passage is arranged in such a way that coins get from the stock compartment into the dispensing compartment as the coin drum rotates around a pivot pin.
US08535120B2 Blade sharpening system for agricultural implements
A blade sharpening system is provide that includes a base and a pendulous arm having a first end rotatably coupled to the base by a pivot joint. The blade sharpening system also includes a sharpener suspended by the pendulous arm and configured to engage a generally circular agricultural implement blade while mounted on the agricultural implement. The pendulous arm is configured to enable movement of the sharpener to accommodate lateral variations in blade profile.
US08535118B2 Multi-spindle chemical mechanical planarization tool
An apparatus for chemical mechanical planarization includes a spindle assembly structure and at least one substrate carrier, which make a linear lateral movement relative to each other while abrasive surfaces of a plurality of cylindrical spindles in the spindle assembly structure contact, and rotate against, at least one substrate mounted on the at least one substrate carrier. The direction of the linear lateral movement is within the plane that tangentially contacts the plurality of cylindrical spindles, and can be orthogonal to the axes of rotation of the plurality of cylindrical spindles.
US08535115B2 Gathering spectra from multiple optical heads
A polishing apparatus includes a platen to hold a polishing pad having a plurality of optical apertures, a carrier head to hold a substrate against the polishing pad, a motor to generate relative motion between the carrier head and the platen, and an optical monitoring system. The optical monitoring system includes at least one light source, a common detector, and an optical assembly configured to direct light from the at least one light source to each of a plurality of separated positions in the platen, to direct light from each position of the plurality of separated positions to the substrate as the substrate passes over said each position, to receive reflected light from the substrate as the substrate passes over said each position, and to direct the reflected light from each of the plurality of separated positions to the common detector.
US08535114B2 Method for manufacturing a precursor lens for a rim-shaped lens
A method for manufacturing an externally circular precursor lens that is processed into a rim-shaped lens includes inputting processing data to specify the shape of the rim-shaped lens, and processing a material block based on the processing data so as to manufacture a precursor lens. An elliptical virtual rim surrounding the precursor lens manufactured at that time is imaginarily set, and is processed based on the processing data up to that range, and, outside the virtual rim, an amount of sag is changed to secure the edge thickness of the precursor lens. This method for manufacturing a precursor lens for a rim-shaped lens reduces an excessive load imposed on a processing tool during processing, allows the precursor lens to be processed into a rim-shaped lens while satisfactorily maintaining its edge thickness without the lack of the edge of the precursor lens, and results in a thin lens.
US08535112B2 Modular box turkey call
A game call having a box piece and a striker piece that contacts and vibrates an exposed edge of at least one box wall to produce sound. The box includes a bottom wall and a plurality of side and end walls that circumscribe an open-sided sound chamber. An appendage or striker pivot post projects from the box and supports a resilient assembly to bias the striker to the pivot post. The striker includes a slotted keyway having an aperture, a channel way and an adjoining recess that supports the pivotal movement of the striker. Striker pieces constructed to various shapes and from a variety of materials and having one or more keyways or deformable retainer assemblies are shown that can be interchanged with the box piece to produce a variety of different sounds.
US08535108B2 Formation method of an organic layer, manufacturing method of an organic electroluminescent element, organic electroluminescent element, and organic electroluminescent display device
A formation method of an organic layer (13) includes a transfer process of forming the organic layer (13) by superposing a donor substrate (30) having a light heat converting layer (32) and a transfer layer (34) formed sequentially to cover at least regions corresponding to organic layer formation regions on a support plate (31) and a transfer mask (40) having openings corresponding to the organic layer formation regions, on each other so that the transfer layer-side surface of the donor substrate (30) comes into contact with the transfer mask (40), and, with the resultant structure placed above a transfer target substrate (20) so that the transfer mask (40) is on the lower side, transferring the transfer layer (34) onto the transfer target substrate (20) via the openings of the transfer mask (40).
US08535107B2 Biophysical geoengineering compositions and methods
Described here are compositions, methods and apparatus for biological and physical geoengineering. Disclosed are inorganic particles, prill, pucks, or floats for dispersal on a body of water. These compositions are found to A) increase yields for pelagic aquaculture, B) increase carbon sequestration, and C) provide immediate relief from global warming by directly increasing surface albedo, reducing sea surface temperatures, and indirectly by increasing cloud nucleation activity. A vertical spar buoy or spar buoy network is provided. The buoys or array of buoys are designed to resist wave motion while supporting an analytical platform below the 100-Year Horizon. Sedimentary deadfall through the 100-Year Horizon is measured and flux of fixed carbon is reported and validated. Issuance of validated carbon sequestration certificates and monetization and trading of those certificates are also described.
US08535105B1 Integrated jack plate
An integrated jack plate, comprising several components, in combination. There is a pair of mirror-configured boat mounting plates, an inner lower boat mounting plate cross member, and an outer lower boat mounting plate cross member. There is also provided, an inner upper boat mounting plate cross member, an outer upper boat mounting plate cross member, and a motor mounting slide plate. There is a hydraulic ram clevis coupled to the motor mounting slide plate and an integrated ram—reservoir—motor unit. Lastly, there is a hydraulic base mount and a travel stop.
US08535103B2 Electrical connector
In one embodiment of the present invention, there is provided an electrical connector comprising an insulative housing having a longitudinal base with a first side and a second side. Extending from the base at the first side is a tongue portion having a first tongue section and a second tongue section, both sections having a first face and a second face. A plurality of passageways are defined on the first faces of both sections. Each of the passageways has a recess located at one end and a plurality of conductive contacts are received in the passageways. Each contact comprises a mating section, a mounting section and a retainer section bridging the mating section to the mounting section whereby the mating section of the contact is free to flex into the recess. In another embodiment of the present invention, there is provided an electrical connector having a socket extending from the base at the second side.
US08535097B2 Electrical connector with improved mating means
An electrical connector comprising an insulative housing, a plurality of terminals, a detect pin and a shell, includes a insulative housing having a terminal seat extending forwardly from a base portion and configuring a tongue, and defining a receiving room between bottom of the tongue and a shell, and a plurality of terminals installed in the terminal seat containing nineteen pins compacting to transmit HDMI signals and with one plus pin compacting to transmit DisplayPort signals, and a shell accommodating the insulative housing and including a first engagement portion, a second engagement portion, and a third engagement portion.
US08535094B2 Elastic member and shielded connector assembly having the same
Disclosure relates to an elastic member mounted in a securing part formed at a male shielded connector or a female shielded connector and configured to establish an electrical connection between the male shielded connector and the female shielded connector when the male shielded connector and the female shielded connector are assembled. The elastic member includes a plate spring having a predetermined length; an elastic piece being elastically deformable and formed by bending a portion of one or both sides of the plate spring in the lengthwise direction of the plate spring; and a fixing member formed on the plate spring and configured to prevent the elastic member from separating from the male shielded connector or the female shielded connector when the male shielded connector and the female shielded connector are disassembled.
US08535092B2 Mini-coax cable connector
A connector of termination assembly for a mini-coaxial cable in different embodiments is made up of an extension tip which is preassembled in a connector body to receive the inner conductor pin on the cable, a first inner sleeve which fits over an exposed end of the dielectric layer, a second outer sleeve which surrounds a compression ring, and a crimping ring is mounted on the outside of the outer sleeve to force the sleeves to be radially contracted into crimping engagement with the cable. Variations of the connector body may be employed for different types of connectors including modifications in the extension tip to facilitate insertion of the conductor into the assembly and color bands to signify the size of cable and intended application.
US08535086B2 Electronic devices using divided multi connector element differential bus connector
In one example an electronic device includes a housing that includes an A/C input or DC input, and at least one circuit substrate that includes electronic circuitry, such as graphics processing circuitry that receives power based on the A/C input or DC input. The electronic device also includes a divided multi-connector element differential bus connector that is coupled to the electronic circuitry. The divided multi-connector element differential bus connector includes a single housing that connects with the circuit substrate and the connector housing includes therein a divided electronic contact configuration comprised of a first group of electrical contacts divided from an adjacent second group of mirrored electrical contacts wherein each group of electrical connects includes a row of at least lower and upper contacts.
US08535082B2 Apparatus for providing a secure connection between different devices
An apparatus for holding at least two devices together is provided with a first securing member, a second securing member, and a connecting member extending between the first and second securing members. The first securing member may be an elongate member having first and second ends such that the elongate member has a length between said first and second ends sufficient to wrap around one of the at least two devices, and the first end of the first securing member having securing means that operates to connect the first end to the second end. The second securing member may receive at least one other of the at least two devices, and may have at least two substantially linearly aligned receptacles. Each receptacle may receive the at least one other of the at least two devices. The two devices may be one or more cords, extension cords, and electrical plugs.
US08535077B2 Card edge connector
A card edge connector for mating with a corresponding daughter card 200 with a locking notch 201 at a side thereof, comprises: an insulative housing 1, a plurality of contacts 2 assembled to the insulative housing 1 and an ejector 3 and a locking member 4 set on two longitudinal ends of the insulative housing 1. The insulative housing defines a central slot 14 along the longitudinal direction. The locking member 4 is formed with a retention portion 41 and a pair of elastic arms 42 extending upwardly from the retention portion 41 and symmetrically located on two opposite sides of the central slot along a transverse direction perpendicular to longitudinal direction, each elastic arm 42 having a locking portion 321 protruding toward each other for locking with the locking notch 201 of the daughter card 200.
US08535076B2 Electrical connector
An electrical connector to be disposed on a circuit board includes a housing with two sidewalls, a plurality of first terminals, and a plurality of second terminals. The first terminals and the second terminals are attached to the one and the other of the sidewalls, respectively, and are situated near a bottom portion of the housing. The first terminal has a flexible first elastic arm portion. The first elastic arm portion extends upward. The first elastic arm portion has a first contact section that protrudes toward the flat conductive member. The second terminal has a flexible second elastic arm portion. The second elastic arm portion extends upward further than an upper end of the first elastic arm portion. The second elastic arm portion has a second contact section that protrudes towards the flat conductive member at a position above than the upper end of the first elastic arm portion.
US08535072B2 Connector
A connector includes a main body, an electrical interface extending from a front end of the main body, and a fixing member pivotably mounted to the main body with a first end. A second end of the fixing member forms a dummy interface similar to the electrical interface.
US08535071B1 Electrical connector
Disclosed is a plug-type connection having a plug and a socket with a plug-in opening for the plug. The socket includes a socket housing and at least one retaining element connected to the socket housing and movable about a first pivot axis. The retaining element secures the plug plugged into the plug-in opening against slipping out of the plug-in opening. A means is provided to displace the retaining element about the first pivot axis out of the position securing the plug against slipping out, thereby releasing the plug, if a specific force acting on the plug opposite to the plug-in direction is exceeded.
US08535063B1 Craniofacial anatomic simulator with cephalometer
A craniofacial anatomic simulator with cephalometer is disclosed and omnidirectional osteogenesis is provided as an example thereof. The craniofacial anatomic simulator (CAS) includes an articulator in which a stereolithographic medical model is mounted. The medical model hereof is modified for this purpose so that the mandibular portion is mounted together with the craniomaxillary portion in a manner which simulates the excursive movement of the temporomandibular joint and the masseteric sling providing both rotational and translational motion. The cephalometer consists of three digital calipers that provide locational data—height, depth and lateral position for any point on the stereolithographic model.
US08535060B2 System and method for detecting a specific cognitive-emotional state in a subject
A system and method is disclosed which detects a specific cognitive-emotional mental state (e.g., passion) in a subject. The system and method utilizes different Internal Personalized Explorer (IPE) stimuli subliminally exposed to the subject on a visual display. Following exposure, the subject performs a target-specific cognitive task and a related behavior (e.g., deciding whether a briefly displayed string of letters is a word or not, and pressing a button to indicate the decision). The decision reaction lime for the behavior is recorded in a computer database. The reaction times are interpreted quantitatively to detect the relative intensity of the specific cognitive-emotional mental state in the subject. A reaction time for a specific individual IPE that is shorter than the mean reaction time for an IPE that does not evoke the emotional state indicates that the specific individual IPE did evoke the emotional state in the subject.
US08535059B1 Learning management system for call center agents
A learning management system provides e-learning to call center agents. Agents can receive training provided in various training formats, which are characterized as fixed-time, flex-time, human-initiated, or system-initiated. A training process flow illustrates how the various training formats can be provided using processes involving agent selection, registration, scheduling, content delivery, and post-training reporting. A modular system provides the training flow and coordinates the function of various call center components to provide training in a seamless and integrated manner using existing call center scheduling systems, such as workflow management components.
US08535058B1 Dental release agent and methods for its use
An oil-free aqueous lecithin composition is suitable as a release agent and lubricant for dental procedures. Layered between a first entity and a second entity during a dental procedure, the composition promotes ready separation of the first entity from the second entity as needed in the procedure.
US08535055B2 Method and kit for producing dental implant drilling guides
A method and kit for producing implant drilling guides positioned at the proper angle and orientation so as to avoid inadvertent damage to critical regions of the patient's jaw when drilling to place dental implant screws. The method works by placing a small post with x-ray visible depth markers in the root of the patient's tooth immediately after tooth extraction. This post, along with guideblocks, optional washers, reduction or expansion guides, and rapidly hardening guide materials (such as acrylics or thermosetting materials) is used to construct a removable guide that anchors to the patient's adjacent teeth, and preserves the location and orientation of the extracted tooth root. Once the root is filled in with new bone, the guide, in conjunction with the X-ray post depth information, can be used to direct drilling along the same route as the old tooth root, thus avoiding critical structures.
US08535052B2 Cap for a gas burner
A cap for a gas burner is disclosed. The cap includes a center portion including a top surface having a periphery; at least one extension extending outward from the center portion, the at least one extension defining a drain channel extending outward and downward from the top surface; and a ledge extending along the periphery. A spill resistant gas burner assembly incorporating such a cap is also disclosed.
US08535045B2 Method of producing a molded article using a deformable cavity insert and deformable cavity insert for a molding system
According to embodiments of the present invention, there is provided a cavity insert for a molding system, the cavity insert having a deformable portion. More specifically, A cavity insert (106) is provided, the cavity insert (106) is for a molding stack (102) for use in an injection mold, the cavity insert (106). The cavity insert (106) comprises a body (122) configured to be received, in use, within a cavity plate (104) of the injection mold; the body (122) defining: a cavity molding surface (124) along an inner portion thereof; a circumferentially deformable portion (123); and an actuator interface (134) configured to cooperate, in use, with a complementary actuating interface (136) that is defined on a compression member (138) to generate a compressive force that selectively elastically deforms the circumferentially deformable portion (123).
US08535043B2 Molds for use in contact lens production
The present invention provides molds useful in contact lens production, which molds incorporate a centering and spacing feature in the form of tabs on one of the mold halves. The spacing feature both centers the mold halves in relationship to each other and permits free flow of excess monomer from the mold. Additionally, the spacing feature aids in height control of the one mold half in relation to the other mold half.
US08535042B1 Apparatus for manufacturing a flanged component and methods of manufacturing the same
An apparatus and methods for manufacturing a flanged component from a composite lay-up are provided. The apparatus includes a support structure coupled to the composite lay-up and a mold ring coupled to the support structure. The mold ring includes a ring guide surface and a radial contact surface that is configured to couple to the composite lay-up. The apparatus further includes a mold plate coupled to the mold ring. The mold plate includes a recessed surface and a plate guide surface, where the recessed surface is configured to couple to the composite lay-up and the plate guide surface is configured to couple to the ring guide surface. The apparatus also includes an autoclave that applies pressure to the mold ring and the mold plate to move the plate guide surface along the ring guide surface to apply pressure to the composite lay-up.
US08535041B2 Addressable flexible patterns
Techniques, methods, systems, and apparatus are disclosed that are useful for creating addressable three-dimensional elements formed on a flexible substrate using continuous roll-to-roll fabrication methods. An array of conductive elements can be formed on a first flexible substrate layer, over which is disposed a second polymer layer containing a three-dimensional micro-scale relief pattern. The second layer can be formed in registration with the underlying electrode pattern. The lowest areas of the micropattern can be etched away, in order to expose the underlying electrode elements. The 3D micropattern can include a volumetric structure capable of being filled with various materials, where the contents of the 3D structure may be further processed by chemical, electrochemical, or physical treatment. The 3D structure may consist of elements in the general form of microvessels disposed in a periodic or non-periodic array.
US08535040B2 Plastic film stretching apparatus
A plastic film (2) is drawn in a different manner. A plurality of rollers (15a, 15b, 15c) are opposed to a base (14). The rollers are operated by a first drive mechanism (22), and the rollers are moved in the lateral direction of the plastic film. Second drive mechanisms (17a, 17b, 17c) act on the rollers, respectively. On the base, at least one roller is pressed against the plastic film, and at least one roller rolls along the plastic film. The plastic film is drawn by that roller.
US08535036B2 Method and apparatus for combining particulate material
A method of selectively combining particulate material, for example plastics material by sintering, comprises providing a layer of particulate material, providing radiation, for example using a radiation source over the layer, and varying the absorption of the provided radiation across a selected surface portion of the layer to combine a portion of the material of the layer. The method may comprise varying radiation absorption by varying the intensity of the radiation incident on the surface portion of the layer, or alternatively may comprise varying the radiation absorptive properties of the particulate material over the selected surface portion of the layer, for example by printing a radiation absorbent material onto the surface portion.
US08535028B2 Downhole positive displacement motor
A downhole positive displacement motor converts hydraulic fluid pressure into rotational torque. The motor includes a non-helical rotor and stator, and upper and lower valve assemblies each comprising cylindrical rotating and stationary elements which define longitudinal passages. The timing of alignment of the passages creates pressure in power pockets in the stator, rotating the rotor. The rotational torque can be used in any application that may require mechanical force to operate or drive a mechanism created for oil, gas, or water production in a down hole application.
US08535027B2 Thermal expansion chambers for airtight containers
A hydraulic pump has a rotor and a hollow housing with a main interior chamber. The rotor is rotatably mounted in the main interior chamber. A smaller interior chamber is separated from the main interior chamber such that the smaller interior chamber retains gas therein when the main interior chamber is filled with a liquid.
US08535026B2 Mechanical system for movement along a housing axis
A mechanism for moving elements in a fluid filled housing using a pump with the element to be moved attached rigidly to the pump or to a port assembly connected to the pump. The pump assembly or port assembly moves as a result of differential pressure created between a first and a second chamber separated from each other by the pump assembly or port assembly. Movement of the fluid in one direction increases or decreases pressure, the pressure change resulting in a net force in one direction or the other.
US08535017B2 Hydraulic gravity ramp pump
A piston type pumping apparatus comprises a vertically oriented cylinder having a top and a bottom with a first aperture. There are first and second passageways for liquid in the cylinder at the top and bottom respectively thereof. A piston is reciprocatingly mounted within the cylinder and has an area against which pressurized fluid acts in the direction of movement of the piston. A hollow piston rod is connected to the piston and extends below the piston and slidably through the first aperture. There is a reload chamber below the cylinder. The piston rod extends slidably into the reload chamber and has a third passageway for liquid communicating thereto. A first one-way valve is located in the third passageway. There is also a fourth passageway that extends from the reload chamber to a source of liquid to be pumped and a second one-way valve therein.
US08535010B2 Axial flow fan
An axial flow fan including a rotation shaft section to be mounted on the rotation shaft of rotation drive means, an inner blade group provided outside the rotation shaft section so as to be coaxial therewith, and an outer blade group provided outside the inner blade group so as to be coaxial therewith, wherein the inner blade group is formed of a plurality of inner blades provided radially around the rotation shaft section, the outer blade group is formed of a plurality of outer blades provided radially around the rotation shaft section, and the velocity V1 of the wind generated by the inner blade group and the velocity V2 of the wind generated by the outer blade group have a relationship of 1.5V1
US08535003B2 Fan frame and heat dissipation apparatus using the same
A fan frame for a heat dissipation apparatus is provided. The fan frame includes an outer frame, an inner frame sleeved in the outer frame and slidable relative to the outer frame, a latching mechanism for mechanically securing the inner frame to the outer frame. The latching mechanism includes one or more resilient latches, one or more receiving portions capable of receiving the resilient latches in a first latched position and a second latched position, and an actuator mechanism connected to the outer frame and capable of resisting the resilient latch to cause elastic deformation of the resilient latch, thereby withdrawing the resilient latch from the receiving portion.
US08535001B2 Fastening of the rotor of a centrifugal pump
The invention relates to a rotor wheel constructed of sheet metal for a centrifugal pump, particularly a multi-stage centrifugal pump, with means for fastening to the drive shaft of an electric motor, wherein the rotor wheel has a central coaxial opening in which a sleeve is fastened coaxially, wherein the sleeve projects out of the rotor wheel on at least one side of the rotor wheel, and wherein the sleeve has, in its inner wall, projecting, axially parallel ridges for fastening into axially parallel notches or grooves of the motor drive shaft.
US08534996B1 Vane segment tip clearance control
A compressor stator vane and rotor blade tip clearance control assembly in which a plurality of stator vane segments each with vanes extending inward are connected to an annular sync ring through eccentric cranks so that circumferential movement of the sync ring will produce radial displacement of the vane segments and control the clearance between the blade tips. An actuator piston is rigidly fixed to the sync ring and forms an actuator chamber with stationary actuator housing. Bleed off pressure from one of the compressor stages is used to move the actuator piston, which moves the sync ring to radially displace the vane segments.
US08534980B2 Systems and methods of loading and unloading a vehicle
Disclosed is system configured to place a load in a motor vehicle. The system includes a beam defining a first end configured to receive the load, and a second end configured to receive a counter force to the load; and a base defining a fulcrum for the beam, such that the second end of the beam receives a constraining force from a ceiling of the vehicle, the constraining force thereby acting as the counter force.
US08534979B2 Front entry power access ramp
An access system for use in a vehicle. The access system includes a frame supported on a vehicle and a ramp having a support surface and a leading edge. The ramp is moveable with respect to the frame between a stowed position, in which the leading edge of the ramp is proximate the frame, and a deployed position, in which the leading edge is positioned away from the frame. A first track and a second track are coupled to one of the frame and the ramp, where the contours of the first and second tracks at least partially define the tilt angle of the ramp with respect to the frame.
US08534978B2 System for loading cargo
A simplified apparatus is provided to exploit certain unique characteristics of DC winches, whereby two winches may be cooperatively joined to load and unload a light-duty truck. Since the speed and torque are linearly related in a DC motor, it possible to manipulate certain parameters, such as the resistance of the armature and the mechanical leverage applied to the load, to result in a stable dynamic between two oppositely-directed DC-motor winches. The novel concept avoids the need for controls to coordinate the winches, and no installation is required that would otherwise limit the use of the truck for other purposes.
US08534976B2 Apparatus for providing a rotation carrier magazine, and method of operating thereof
An apparatus for supporting a plurality of carriers or substrates is described. The apparatus includes a vacuum chamber and a rotatable support for supporting the plurality of carriers or substrates, wherein the support is provided within the vacuum chamber and is configured for rotating the supported plurality of carriers or substrates around a rotation axis.
US08534975B2 Substrate transport apparatus and method for manufacturing magnetic recording medium
A substrate transport apparatus comprises chambers connected to each other through a gate valve, a transport mechanism configured to open the gate valve and to transport a carrier between the chambers along a transport path, a sensor configured to detect the carrier before the carrier reaches a stop position in the chamber, and a controller configured to cause the gate valve to start closing based on the detection signal from the sensor.
US08534970B2 Shipping chocks and methods for loading cylindrical-shaped objects for transport
Shipping chocks for securing a transverse cylindrical-shaped object on top of at least two vertically oriented cylindrical-shaped objects are disclosed. Methods of loading cylindrical-shaped objects in both vertical and horizontal orientations, using the chocks, allows for more cylindrical-shaped objects to be shipped in a shipping container in a safe and effective manner that reduces shipping costs.
US08534964B2 Drilling device with oil supply unit
A drilling device having an oil supply tank disposed at a position where the oil supply tank is less likely to collide with surrounding objects. This device includes a fixing member (12) fixed to a workpiece, a column (14) extending upward from the fixing member, a tubular slide unit (16) that is slidable along the column, a tool body (18) disposed on the tubular slide unit, and an oil supply tank (20) provided between the tool body and the fixing member and removably fixed to the tubular slide unit. The tool body is provided with a cutting oil supply passage having a cutting oil inlet (109) disposed toward the fixing member, while the oil supply tank is provided with a cutting oil outlet disposed upward. The tool body is displaced upward on the column and the oil supply tank is moved close to the tool body from the lower side of the tool body, whereby the cutting oil outlet of the oil supply tank is connected to the cutting oil inlet of the tool body.
US08534954B2 Pot hole repair patch and method of installation
A road patch for repair of potholes is disclosed. A pothole is preliminarily repaired with asphalt fill and compacted per current standard practice. Thereafter, a road patch is placed upon the compacted top surface of the asphalt fill, overlapping onto the adjacent road surface and compressed. The road patch forms a water proof seal over the surface area of the patch preventing water from seeping into the repaired pothole. The patch also resists crack propagation and minimizes the potential of asphalt chipping and the breaking down of the asphalt fill.
US08534953B2 Roadway structure having improved adhesive properties
A method for the production of a roadway structure, the method including: (i) applying a primer to a support structure; (ii) applying a plastic membrane to the support structure that is primed according to step (i); and then (iii) applying an adhesive composition that includes a) at least one solid epoxide resin, and b) at least one thermoplastic polymer that is solid at room temperature, and (iv) applying a bitumen-based support layer.
US08534952B2 Visual highlight accessory for highway guardrails
A visual highlight accessory for attachment to highway guardrails has a paint coating and a clear varnish overcoating with mica particles for making the visual highlight accessory and the guardrail on which the visual highlight accessory is mounted readily visible to persons in vehicles travelling along a highway along which the visual highlight accessory borders. The visual highlight accessory has orifices corresponding to orifices in the guardrails to facilitate mounting of the visual highlight accessory on a guardrail.
US08534948B2 Dispenser with a cam path
A dispenser includes a cam path and a mating guide pin to provide a closed position or an open position for the dispenser. The dispenser is selectively rotatable causing the mating guide pin to travel along a cam path to rotate between slanted, unslanted, and slanted downward positions. The mating guide pin in the cam path causes the open position to allow product delivery and causes the closed position to provide a seal to prevent product leakage. In an implementation, the dispenser is selectively guidable along a helical guide slot to an upward position for product application and to a downward position to retract the applicator. When the dispenser is selectively rotatable along the helical guide slot to a retracted position, the dispenser is in a stored state.
US08534941B2 Expanding a sheet to be cut when an ink dot is present in a cut position
A printing apparatus has: a dot discrimination section that discriminates whether a print dot is present in a discrimination target area D including a cut position at which an elongated sheet is cut in a sheet width direction, the discrimination target area being at least either one of a front edge area D1 or a rear edge area D2 having a predetermined length in a longitudinal direction of the sheet in a print area; and a print section that prints after providing a margin area adjacent to an outer side of either one of the front edge area or the rear edge area where whether the print dot is present or not is discriminated when the dot discrimination section discriminates such that the dot is present, and that prints without providing the margin area when the dot discrimination section discriminates such that the dot is not present.
US08534939B2 Tape printing apparatus with tape cassette identifying unit
A CPU detects whether or not a type of a tape cassette housed in a cassette housing portion is a stripped-tape accommodating cassette that creates an after-printed tape with a separator being peeled off from its adhesive layer. In case the CPU detects that the type of the tape cassette in the cassette housing portion is a stripped-tape accommodating cassette that creates an after-printed tape with a separator being peeled off from its adhesive layer, only one after-printed tape in predetermined length with a separator being peeled off from its adhesive layer is made subject to tape printing, and consequently conveyed to a cutting point, whereby tape printing is terminated.
US08534934B1 Camera stabilization device and method of use
The present invention is a dynamically balanced, lightweight multifunctional, camera stabilization device that allows a film or digital video camera to be flown out of arms reach of the operator and maintain orientation toward the subject matter, while allowing the operator smooth control of rotation or pan of the camera.
US08534932B2 Apparatus and method for thermal connection of optical waveguides
A splicer comprises a positioning device, in which the fiber ends in general have a residual offset. A memory stores a predetermined relationship between the possible offset and a parameter which controls the application of heat. The parameter which controls the application of heat, for example the splicing time for a predetermined splicing current, is defined on the basis of an actual offset which can be recorded by means of cameras.
US08534931B2 Active optical cable (AOC) and a method and apparatus for performing power management in the AOC
An active optical cable is provided that incorporates a power management solution. The AOC has plugs that are configured to mate with respective USB sockets. The AOC is used to interconnect a USB host with a USB device. To the USB host and to the USB device, the AOC appears to be a standard USB electrical cable. Each of the plugs of the AOC has an optical-to-electrical and an electrical-to-optical (OE/EO) conversion module that converts electrical USB signals output from the USB host or USB device into optical signals and converts optical signals carried on the optical fibers of the AOC into electrical USB signals. The plugs include controllers that monitor certain conditions of the AOC and that select the power levels to be used in the plugs based on detected conditions.
US08534929B2 Optical fiber connector
An optical fiber connector includes an optical fiber cable including two optical fibers; and a connector plug connected to opposite ends of the optical fiber cable for electrical connection to an electronic device. The connector plug includes a shell, a photodiode, a laser diode; and an electrical connector for electrical connection to an electronic device. The photodiode, the laser diode and the electrical connector are housed in the metallic shell, the photodiode is optically coupled to a distal end of one corresponding optical fiber and electrically coupled to the electrical connector, the laser diode optically is coupled to a distal end of the other optical fiber and electrically coupled to the electrical connector.
US08534925B1 Differential bearing system for an axle assembly
An axle assembly with an axle housing, a case, a bearing, a hollow bearing adjuster and a locking system. The bearing is received onto a bearing hub on the case and supports the case for rotation relative to a bulkhead structure in the axle housing. The bearing adjuster has a threaded portion, which is threaded to the axle housing, and an inboard end surface that is abutted against an outboard bearing race of the bearing. The locking system inhibits relative rotation between the axle housing and the bearing adjuster. The locking system consists of a threaded hole in the bulkhead structure, a plurality of circumferentially spaced apart adjustment apertures formed in the bearing adjuster and a threaded fastener that is threadably received into the threaded hole. The threaded fastener extends into one of the adjustment apertures.
US08534924B2 Wheel bearing unit
The invention relates to a wheel bearing unit (1) for a vehicle wheel, comprising a hub element (2, 3) which has a axially (a) extending cylindrical section (4) to be supported by a bearing arrangement (5) and which has a radially (r) extending flange section (6) for fixing the vehicle wheel and/or a brake disk at a face side (7) of the flange section (6). To ensure a simple design with high stability the invention is characterized in that the hub element (2, 3) consists of a first part (2) comprising the cylindrical section (4) and the flange section (6) and of a second part (3), wherein the second part (3) has means (8) for centering a wheel rim of the vehicle wheel and/or the brake disk and wherein the first part (2) and the second part (3) are connected by connection means (9).
US08534921B2 Marine drive shaft-bearing structure
To provide a marine drive shaft-bearing structure capable of simply filling grease without an effort and at a reduced cost. A marine drive shaft-bearing structure includes a bearing body disposed between an engine and an impeller for propulsion. Front and rear bearing members are received in a bearing chamber within the bearing body so as to rotatably support a drive shaft which connects the engine with the impeller. A grease filling portion is adapted to fill grease into the bearing chamber. The grease filling portion includes a grease filling port formed in the bearing body so as to communicate with the bearing chamber and a grease tank for storing the grease and for being detachably attached to the grease filling port.
US08534918B2 Semiautomatic slide mechanism
A semiautomatic slide mechanism includes a slide board and a slide seat slidably connected therewith. The slide board is formed with a slide rail divided into a first slot and a second slot for early half and later half of the sliding travel. Two racks are disposed on different sides of the first and second slots. The slide seat is formed with a guide slot. A guide member is slidably disposed on the slide seat corresponding to the guide slot. An elastic member is disposed in the guide member. A driving spring member is disposed on the slide seat for driving the guide member. A gear is disposed between the slide board and the slide seat and engaged with one of the racks. The gear has a shaft member connected with the driving spring member and the elastic member and slidably extending through the guide slot and the slide rail.
US08534907B2 Device for accelerating mixing and dissolving process of liquid water
A device for accelerating mixing and dissolving processes of liquid water and powder. The device includes a main body formed in a bottle cap shape including a top surface and a side periphery surface, and a shaft disposed at a center of an upper portion of the main body in such a manner as to be inserted into a shaft insertion groove formed at a center of an impeller. The top surface of the main body has two or more introducing portions to introduce the liquid water and the powder into the device, and the side periphery surface of the main body has two or more discharging portions to discharge the liquid water and the powder introduced into the device through the two or more introducing portions to the outside of the device.
US08534905B2 Adjustable orbit imbalance compensating orbital shaker
An orbital shaker apparatus is provided, including a first shaft connected to a first bearing assembly at a first end and a mounting portion at the other. The first shaft is rotatable about a first shaft axis, and is connected to a motor. The second shaft has a bearing assembly on the mounting portion at one end and a platform at the other, and is aligned parallel to and offset from the first shaft by a distance. A counterweight rotor assembly is coupled to the mounting portion, and rotated by a belt driven by a pulley connected to the rotating shaft of a counterweight motor. The counterweight assembly includes two counterweight bearings, each having a counterweight wedge. The platform also includes supports for objects to be secured thereto. In use, as the counterweight rotor rotates, the second shaft, second bearing assembly, and platform describes a circular orbit with diameter 2R.
US08534903B2 Drive arrangement in a degassing extruder
The invention relates to a vented extruder (1) for the devolatilization of a polymer material. The vented extruder (1) encompasses at least one drive (4), at least one gearbox (5), at least one rotatably driven extruder screw (3), at least one first material feed (6) and at least one extrudate outlet (13). A feature of the vented extruder (1) according to the invention is that the drive, encompassing drive (4) and gearbox (5), has been provided in the region of that end of the extruder screw (3) that is downstream in relation to the direction of conveying of the polymer.
US08534900B2 Interleaved lighting system for 2D-3D display having orthogonally arranged light extraction features
A light guide plate for a backlight comprises a light transmissive medium. The light transmissive medium preferably has two pairs of opposing sides and a top surface. Also provided is a plurality of interleaved regions of elongated light extraction features on the top surface of the light transmissive medium. Each light extraction figure is configured to extract light injected into the light guide plate and into a direction away from the top surface of the light guide plate. Each elongated light extraction feature has a long dimension and a short dimension. The light extraction features in a first set of the regions are arranged with their long dimension orthogonal to the long dimension of the light extraction features in a second set of the regions.