Document Document Title
US08329940B2 18β-glycyrrhetinic acid derivatives and synthetic method thereof
The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5.
US08329939B2 Process for the preparation of halogenated benzoic acid derivatives
The present invention comprises a process for the preparation of 3-chloro-2-fluoro-5-trifluoromethyl benzoic acid of the formula or of a salt thereof. 3-Chloro-2-fluoro-5-trifluoromethyl benzoic acid or salts thereof are versatile intermediates for the preparation of active pharmaceutical or agrochemical agents.
US08329936B2 Method for producing cyanoacrylate esters in the presence of transition metal catalysts
The present invention relates to a method for producing cyanoacrylic acid esters. The method is based substantially on a transesterification reaction, wherein the transesterification reaction is performed in the presence of at least one transition metal catalyst that is formed by reacting at least one hydroxyl group-containing support material with at least one transition metal alkoxide.
US08329926B2 Antiviral compounds
The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
US08329924B2 Compounds and methods for the treatment or prevention of Flavivirus infections
The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
US08329918B2 Selective alpha 2B/2C agonists
Described herein are compounds useful as agonists of alpha 2B/2C receptors. Pharmaceutical compositions including the presently described compounds and methods of treatment of diseases and conditions with the presently described compounds also are disclosed.
US08329913B2 Carbazole derivative, solvate thereof, or pharmaceutically acceptable salt thereof
An object of the present invention is to provide novel carbazole derivatives, solvates thereof, or pharmaceutically acceptable salts thereof having an excellent adipose tissue weight reducing effect, hypoglycemic effect, and hypolipidemic effect, which are useful as a preventive and/or therapeutic agent for fatty liver, obesity, lipid metabolism abnormality, visceral adiposity, diabetes, hyperlipemia, impaired glucose tolerance, hypertension, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, and the like.The above-mentioned object can be achieved by carbazole derivatives, solvates thereof, or pharmaceutically acceptable salts thereof, wherein the carbazole derivatives are represented by the following general formula (I): (In the formula (I), the ring A represents phenyl group or the like; X represents —O— or the like; Y represents ═N— or the like; a and b represent methylene group or the like; both V and Z represent —O— or the like; W represents a C1-C10 alkylene group whose 1 or 2 hydrogen atoms may be substituted by a phenyl group or a C1-C6 alkyl group; 1,2-phenylene group; 1,3-cyclohexyl group; or the like; R1 represents methyl group or the like; R2 represents methoxy group or the like; and R3 represents carboxy group or the like.).
US08329910B2 Quinolines for the treatment of PI3K-δ mediated diseases
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including nut not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
US08329909B2 Method for producing 2-azaadamantane compound from bicyclocarbamate compound
To provide a novel method for producing a 2-azaadamantane compound from a bicyclocarbamate compound.In accordance with the following scheme: a bicyclocarbamate compound represented by the formula (1) is reacted with a halogenating agent to produce a 2-azaadamantane carbamate compound represented by the formula (2), and the 2-azaadamantane carbamate compound is subjected to hydrogenolysis to produce a 2-azaadamantane compound represented by the formula (3) (in the formulae, R1 is hydrogen or the like, each of R2 and R3 which are independent of each other, is a hydrogen atom or a C1-6 alkyl group, Ar is an aryl group which may be substituted by Ra, Ra is halogen or the like, X is a halogen atom, and Y is X or a hydrogen atom).
US08329908B2 Dual action antibiotics
The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:
US08329903B2 Light-emitting element including organometallic complex including pyrazine derivative
An organometallic complex is provided by which favorable red-color light emission can be obtained. Further, an organometallic complex having a peak of light emission at about 620 nm is provided because the wavelength of light which is perceived as excellent red-color light is about 620 nm. Furthermore, an organometallic complex is provided by which red-color light emission with high luminous efficiency (cd/A) can be obtained. An organometallic complex represented by the following general formula (G2) and a light-emitting element, a light-emitting device, and an electronic device including the organometallic complex represented by the following general formula (G2) are provided.
US08329898B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these
The present invention relates to pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, methods for their production and doped organic semiconductor material which use such quinazolines.
US08329896B2 Spirooxazine radical derivatives and reversible isomerization reaction
The present invention can provide new spirooxazine radical derivatives of the following general formula (1) which have chromic property enabling the distinction between the radical species and the cation species on the basis of absorption wavelength:
US08329895B2 Cefdinir acid double salt and method for producing the same
A compound represented by Formula I, wherein M represents Na+, K+, NH4+, or Cs+; and 1) when Y represents SO42−: when m=1, then n=1; and when m=0.5, then n=1.5; and 2) when Y represents PO43−, when m=1, then n=2. The compound has good solubility and high bioavailability and can be formulated into oral pharmaceutical preparations and pharmaceutical preparations for injections.
US08329891B2 Methods for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis
Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate ActRII signaling and cell adhesion. Agents are tested that modulate cell adhesion, detachment, invasion and viability. Agents that modulate the expression, phosphorylation, function and translocation of ActRII signaling pathway members also can predict agents that modulate cell adhesion, detachment, invasion and viability. The methods have utility in identifying agents that prevent cancer cell metastasis, wound dehiscence, aortic dissection and aid retina attachment and skin replacement and fertility.
US08329879B2 H3LMN compound used as radioactive agent for treatment of liver cancer and manufacturing method thereof
H3LMN series compounds used as radioactive agents for treatment of liver cancer and a manufacturing method thereof are revealed. 2-thioethylamine hydrochloride is reacted with triphenylmethanol for protection of thiol to obtain 2-[(triphenylmethyl)thio]ethylamine. Then obtain N-[2-((triphenylmethyl)thio)ethyl]chloroacetamide by a transamidation reaction between 2-[(triphenylmethyl)thio]ethylamine and chloroactyl chloride. Next produce a amine-amide-thiol ligand-N-[2-((triphenylmethyl)thio)ethyl][2-((triphenylmethyl)thio)ethylamino]acetamide by a substitution reaction of N-[2-((triphenylmethyl)thio)ethyl]chloroacetamide and 2-[(triphenylmethyl)thio]ethylamine. After respective reaction with 1-bromotetradecane, 1-bromohexadecane and ethyl 16-bromohexadecanoate, H3LMN series compounds are obtained. These amine-amide-dithiols quadridentate ligands can react with MO3+ (M=Tc or Re) to produce electrically neutral complexes. The complexes have high lipophilicity, allowing them soluble in lipiodol to be applied to radiation therapy for liver cancer.
US08329876B2 Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs and related polymers having a terminal thioester moiety capable of specifically conjugating to the α-amine of a polypeptide having a cysteine or histidine residue at the N-terminus. The invention provides reactive thioester-terminated PEG polymers that have suitable reactivity with an N-terminal cysteine or histidine residue of a polypeptide to produce an amide bond between the PEG molecule and the polypeptide.
US08329871B2 Process of purifying coagulation factor VIII
A process of purifying or enriching coagulation FVIII employing chromatography comprising the steps of providing a fraction containing FVIII in an aqueous solution having a high ionic strength; contacting the fraction containing FVIII with a multimodal resin; optionally washing the multimodal resin having FVIII adsorbed with an aqueous washing buffer; eluting FVIII containing fractions by an aqueous elution buffer comprising at least one amino acid which is positively charged at pH 6 to 8; and optionally collecting FVIII containing fractions in purified or enriched form.
US08329870B2 Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof
The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous solutions or specifically for the formation of water-soluble covalent fibrinogen conjugates. A preferred conjugate is a hyaluronic acid-fibrinogen conjugate and fibrin adhesive, clot or matrix derived from it. Methods of preparation and methods of use in tissue repair and regeneration are also disclosed.
US08329867B2 CTLA4-Ig immunoadhesins
The present application relates to CTLA4-Ig immunoadhesins that target CD80 and CD86, and their use, particularly for therapeutic purposes.
US08329866B2 Long acting VEGF inhibitors and methods of use
Disclosed are polymer sFlt-1 conjugates, variants of sFlt-1, compositions comprising such conjugates and variants, including cysteine variants of sFlt-1. Also disclosed is the use of such conjugates, variants and compositions in methods to inhibit the activity of VEGF, to inhibit angiogenesis, and to treat or reduce at least one symptom of diseases and conditions in which it is desirable to inhibit VEGF activity and/or angiogenesis.
US08329864B2 Agent derived from tortoise spleen stimulating mammalian hemopoiesis
The present invention relates to a proteinaceous extract derived from tortoise spleen and to a tetrapeptide FTGN, which have stimulatory activity on hematopoietic cells. In particular, this tetrapeptide enhances hemopoietic reconstruction, and bone marrow re-population, reduced as a consequence of a high dose of radiation or chemotherapy exposure. The invention further provides pharmaceutical compositions comprising as an effective ingredient the proteinaceous extract or the FTGN tetrapeptide and ex vivo and in vivo methods of treatment employing them.
US08329858B2 Method of controlling oil-absorbing properties of a silicone rubber powder
A method of controlling oil-absorbing properties of a silicone rubber powder characterized by keeping a silicone rubber powder in hot storage at a temperature in the range of 40° C. to 150° C. or in cold storage at a temperature in the range of 0° C. to 10° C.
US08329855B2 Thienocoronene-imide semiconducting compounds and polymers
Disclosed are new semiconductor materials prepared from thienocoronene-imide-based small molecule and/or polymeric compounds. Such compounds can exhibit high carrier mobility and/or good current modulation characteristics. In addition, the compounds of the present teachings can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.
US08329854B2 Synthesis of tri-component resins
A resinous compound of the formulas or a salt thereof, wherein G1 is —X1C(O)OR1, —X2OC(O)R2, or —X2OH; G2 is R4, R12, —C(O)R2, —C(O)X1C(O)OR1, or —C(O)X2OC(O)R2; R1 is an alkyl having from 10 to 80 carbon atoms; R2 is an alkyl having from 2 to 40 carbon atoms; each R3 and R4 is independently hydrogen, alkyl, arylalkyl or alkylaryl; each R5 and each R6 is independently hydrogen or alkyl; X1 and X2 are both a straight or branched alkylene group; t1 is 1 to 20; t2 and t3 is independently 0 to 20; u1 is 1 to 30; u2 and u3 is independently 0 to 30; each R7 and each R8 is independently hydrogen, alkyl, or alkoxyl; each R9 and each R10 is independently hydrogen, alkyl, or alkoxyl; Ar is a substituted or unsubstituted aromatic moiety; p is 1 to 5; q is 1 to 12; A⊖ is selected from the group consisting of Cl−, Br−, I−, HSO4−, HSO3−, CH3SO3−, NO3−, HCOO−, CH3COO−, H2PO4−, SCN−, BF4−, ClO4−, SSO3−, PF6−, and SbCl6−; and J is alkyl, arylalkyl, or alkylaryl.
US08329849B2 Organic silicon compound and material for forming silica-based fine particle
An organic silicon compound includes a specific alkoxyorganopolysiloxane portion, a portion including an alkoxysilane group, the portion being bonded to the polysiloxane portion, and a portion including a resin-compatible chain or a reactive functional group, the portion being bonded to the polysiloxane portion.
US08329846B2 Bisphenol-A replacement materials
Polymers may include a plurality of tetradecahydroanthracene moieties. Such polymers may be used to make food or beverage containers or medical devices. Food or beverage containers or medical devices may be coated with polymers including a plurality of tetradecahydroanthracene moieties.
US08329845B2 Divided redox-curing type composition
The present invention provides a divided redox-curing type composition including a first part in which at least an oxidizing agent (b) is dissolved in a first radical monomer including a radical monomer (a) having an acidic group and/or a hydrophilic group; and a second part in which at least an aromatic sulfinate (d) is dispersed in a second radical monomer including a radical monomer (c) having neither an acidic group nor a hydrophilic group. According to the present invention, a redox-curing type composition capable of securing a time necessary for an adhesion operation and exhibiting high bond strength not only at the initial stage of adhesion but also over a long period of time thereafter in application to a wetting material such as a tooth or a bone as well as a tooth crown repairing material such as a metal or porcelain.
US08329843B2 Method for producing amide compound
A method for producing an amide compound from a nitrile compound in an aqueous medium in the presence of a catalyst having a nitrile hydratase activity wherein the concentration of benzene in the aqueous medium is 4.0 ppm or less and a method for producing an amide-based polymer excellent in quality from the amide compound. Also provided are a method for more efficiently producing an acrylamide with higher quality by a microbial catalyst containing a nitrile hydratase and the like and a method for producing an acrylamide-based polymer, which is excellent in hue, has a good balance between water solubility and high molecular weight and is excellent in quality.
US08329842B2 Ophthalmological composition and use thereof
The subject matter of the present invention is an ophthalmologic composition having an UV absorber and a violet absorber, wherein a high transmission is achieved in the blue light spectrum, and an eye implant, in particular an intraocular lens, which is produced with this ophthalmologic composition.
US08329839B2 Melt-processible poly(tetrafluoroethylene)
Melt-processible, thermoplastic poly(tetrafluoroethylene) (PTFE) compositions are disclosed and methods for making and processing same. Additionally, products comprising these compositions are described.
US08329833B2 Nano-linked metallocene catalyst compositions and their polymer products
The present invention provides polymerization catalyst compositions employing novel dinuclear metallocene compounds. Methods for making these new dinuclear metallocene compounds and for using such compounds in catalyst compositions for the polymerization and copolymerization of olefins are also provided.
US08329828B2 Heat-shrinkable polyester film and process for producing the same
A heat-shrinkable polyester film is provided which exhibits a high shrinkability in a high-temperature range with a main shrinking direction oriented in a longitudinal direction thereof, though not shrinking in the longitudinal direction in a low-temperature range, possesses an extremely high mechanical strength in a transverse direction orthogonal to the main shrinking direction, and, in particular, can be utilized suitably as a film for forming a jacket label of a battery or in similar applications.
US08329826B2 Surface modification of interpenetrating polymer networks
Surface modification methods for an interpenetrating polymer network (IPN) hydrogel to provide a basis for cell or tissue attachment are provided. The method involves the activation of functional groups on the surface of the IPN hydrogel. The activated functional groups are then reacted with amine-containing molecules or hydroxyl-containing molecules. The methods (i) can be performed in an aqueous environment and do not require the use of any organic solvent, (ii) do not require UV treatment, thereby avoiding denaturation of the IPN hydrogel or proteins, and/or (iii) can be performed as a one pot reaction.
US08329809B2 Use of an acrylic dispersing agent—associative thickener pair in an alkide paint for improving the retention of its gloss level
The invention consists of the use, in an alkide resin formulation in an aqueous phase, of a dispersing agent/thickener pair: the dispersing agent is a copolymer of (meth)acrylic acid with an oxyalkylated monomer possessing a polymerizable function and terminated by hydrogen or an alkyl group having from 1 to 4 carbon atoms, the thickener is an associative thickener containing at least one hydrophobic group which is a polystyrylphanyl, preferentially chosen from among distyrylphenyl, tristyrylphenyl, and mixtures thereof, and which is very preferentially tristyrylphenyl. This combination makes it possible to improve the brightness level retention of the paint film over time, while ensuring that the aqueous formulation has the desired rheology.
US08329804B2 Flame retardant thermoplastic resin composition
A flame retardant thermoplastic resin composition comprises 100 parts by weight of a rubber-modified aromatic vinyl copolymer resin (A) and about 10 to about 30 parts by weight of a brominated diphenyl ethane mixture (B) including about 55 to about 85% by weight of hexabromodiphenyl ethane. The rubber modified aromatic vinyl copolymer resin (A) according to the present invention is a polymer resin wherein grafted rubbery polymers are dispersed in the form of particles in a matrix of vinyl copolymer. The rubber-modified aromatic vinyl copolymer resin (A) includes grafted rubbery polymers in an amount of about 10 to about 100% by weight and the matrix of vinyl copolymer in an amount of about 0 to about 90% by weight. The brominated diphenyl ethane mixture (B) may have about 1 to about 25% by weight of diphenyl ethane having an odd number of bromine substituents.
US08329801B2 Polyamide-based high-performance self-adhesive powder without adhesion promoter
The invention provides a self-adhesive composition in powder form for the coating of metallic substrates, composed of homopolyamide (A) selected from PA11 and PA12, copolyamide (B), calcium carbonate and, optionally, at least one component selected from a pigment or dye, an anti-crater agent or spreading agent, a reductant, an antioxidant, a reinforcing filler, a UV stabilizer, a fluidizing agent and a corrosion inhibitor, said composition being devoid of silane-type adhesion promoter or of an adhesion promoter containing an epoxy, alcohol and/or carboxylic acid function, or derivatives thereof, and having a dry-state modulus and/or a wet-state modulus of greater than or equal to 2200 MPa [Standard NF EN ISO 527]. The invention also relates to a composite material comprising a metallic substrate directly coated with a coating film resulting from the melting of said composition, the adhesion of the coating film to the metallic substrate being greater than 3 after 2000 hours of salt fog before and after drying, in accordance with Standard NFT 58-112.
US08329796B2 Mixtures of diisononyl esters of terephthalic acid, method for the production thereof and use thereof
The invention relates to mixtures of diisononyl esters of terephthalic acid, characterized in that the isomeric nonyl radicals bound in the ester mixture have an average degree of branching of 1.0 to 2.2. Said mixtures can advantageously be used as softeners or part of a softener composition in plastics or plastic components.
US08329795B2 Oil based polyols or diacids esterified with oxo-acids or oxo-alcohols for producing plasticizers
Oxo-diesters of cyclic olefins, methods of making them and their use as plasticizers in polymer compositions are disclosed.
US08329791B2 Phosphonate compound and flame retardant styrenic resin composition including the same
The present invention provides phosphonate compounds represented by Chemical Formula 1. In addition, the invention provides flame retardant styrene resin compositions comprising (A) styrene resin, (B) polyphenylene ether resin, and (C) the phosphonate compound. The flame retardant styrene resin compositions according to the invention: can provide protection against fire, exhibit improved impact strength, and can be environment-friendly.
US08329789B2 Stabilizer composition for halogen-containing polymers
The present invention relates to a stabilizer composition for halogen-containing polymers comprising titanium dioxide and at least one nitrogen-containing compound, wherein the titanium dioxide has a photo-electromotive force (photo-EMK) in the μs-range >−15 mV and a photo-electromotive force in the ms-range >+5 mV.
US08329787B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions
Hindered amines represented by the general formula (I): (wherein R is an alkyl or hydroxyalkyl group having 1 to 30 carbon atoms or alkenyl having 2 to 30 carbon atoms; n is an integer of 1 to 4; when n is 1, R1 is alkyl having 1 to 22 carbon atoms, alkenyl having 2 to 22 carbon atoms, or a group represented by the general formula (III): (R is as defined above), while when n is 2 to 4, R1 is an n-valent organic group having 2 to 20 carbon atoms). When added to synthetic resins or coating materials, the amines can impart long-period stabilizing effect to the resins or the materials and exhibit excellent resistance to extraction with acid rain or chemicals.
US08329786B2 Modified binder polymer for coating compositions
A film-forming binder polymer for a coating composition such as a paint, varnish or woodstain where the polymer is modified by the presence of bonded moieties derived from plant gum, particularly plant fibre gum obtainable from plant fibre, especially corn fibre gum and more particularly moieties derived from proteo-xylans and/or furanose. The modified binder polymer minimises the need to use coalescing solvents without producing poor dried paint coatings which fail the scrub resistance tests also improves the opacity of the dried coating composition.
US08329783B2 Toner porous particles containing hydrocolloids
The present invention is toner particle that includes a continuous phase of binder polymer and a second phase of hydrocolloid. The particle has a porosity of at least 10 percent.
US08329775B2 Visible light absorbers for ophthalmic lens materials
Azo compounds that block visible light are disclosed. These light absorbers are particularly suitable for use in intraocular lens materials.
US08329771B2 Photobase generator
The object of the present invention is to provide a photobase generator capable of efficiently generating amines (tertiary amines and amidine) high in catalytic activity by sensing light with a wavelength of from 350 to 500 nm (especially, from 400 to 500 nm).The present invention is a photobase generator characterized in being represented by general formula (1) or (2).Y+ is a quaternary ammonio group of general formula (3) to (5), and X− is a counter anion selected from among a borate anion, a phenolate anion, and a carboxylate anion.
US08329769B2 Facile synthesis of microporous triple-bond based polymer networks using acetylene gas as a building unit
Disclosed is a method for synthesis of micro-porous triple-bond based polymer networks using acetylene gas. According to the disclosed methods for synthesis of micro-porous triple-bond based polymer networks, acetylene gas interconnects building units having iodine and/or bromine functional groups by coupling reactions to provide micro-porous triple-bond based polymer networks.
US08329767B2 Membrane production
The present invention is a method for forming a hydrophilic polymer membrane for use in a membrane electrode assembly, comprising the polymerization of a material or materials from which the membrane may be formed, wherein the polymerization is by UV curing.
US08329765B2 Fischer tropsch process
Process for converting synthesis gas to hydrocarbons in a slurry reactor in the presence of a Fischer-Tropsch catalyst comprising cobalt and zinc oxide. The process is carried out by a) activating the Fischer-Tropsch catalyst with a reducing gas consisting of hydrogen and an inert gas at a temperature between 330 and 400° C., and b) contacting the activated Fischer-Tropsch catalyst from step a) with synthesis gas in the slurry reactor in order to convert the synthesis gas into hydrocarbons.
US08329764B2 Defoaming method
A defoaming method capable of destroying foams generated when a container is filled with drink, or the like, efficiently at a high speed and destroying foams effectively even in the case of a container having a narrow mouth. Liquid surface (6) in a container (1) is irradiated with pulse-like light (2) and a pulse-like sound wave (8) is generated from an irradiated point (7) as a sound source. The pulse-like sound wave thus generated propagates from the sound source as a strong spherical wave to reach a bubble (9) and to destroy the bubble. It can also destroy a bubble located at a place remote from the optical path quickly, thus destroying bubbles efficiently at a high speed. Alternatively, pulse-like light is condensed at a gas portion above the liquid surface and the bubbles can be destroyed with a shock wave generated by breakdown phenomenon.
US08329762B2 Nanometric calcium phosphate platelets
The present invention provides calcium phosphate platelets with a length between 250 nm and 800 nm and methods for producing the calcium phosphate platelets. The platelets may be used to provide dispersions or colloidal dispersions obtained by suspending the platelets in the presence of a dispersing agent. The platelets may be used in reinforcing fillers, polishing agents, building materials, additives for oral formulations, in dentrifices or in encapsulating agents.
US08329760B2 Pharmaceutical composition
A pharmaceutical compositions in the form of an emulsion and containing a continuous liquid phase, for example, an aqueous phase, liquid droplets dispersed in the continuous phase, a pharmaceutically active compound, a Hseih enhancer, and a hydrocolloid emulsifying agent and in which, for example, the active compound is dissolved in the aqueous phase or in the liquid droplets, and the use of such composition to treat a condition in a patient, for example, diabetes.
US08329758B2 Skin sanitizing antimicrobial alcoholic compositions
This invention relates to an antimicrobial skin sanitizing composition for disinfecting skin, and particularly, hands. The composition contains at least 60 percent of an aliphatic alcohol having from 1 to 4 carbon atoms, from about 0.1 to about 5 weight percent of a thickening agent, and an effective amount of a GRAS or amino acid neutralizer to neutralize the thickening agent.
US08329755B2 Methods for treating retroviral infections
The present invention provides compositions for treating an HIV infection comprising administering a compound according to formula I where Ar, R1-R5, R11c and X1 are as defined herein with at least one carrier, excipient or diluent.
US08329754B2 Squaramide derivatives as CXCR2 antagonist
The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
US08329752B2 Composition for administering an NMDA receptor antagonist to a subject
The invention provides compostions for administering memantine to a subject. Memantine in an extended release form containing 22.5 to 30 mg memantine or a pharmaceutically acceptable salt achieves particular pharmacokinetic criteria such as change in plasma concentration of memantine over time and ratio of maximum memantine plasma concentration to mean memantine plasma concentration.
US08329751B2 Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors
The invention relates to aryl-sulphonamido compounds endowed with inhibitory activity against metallo proteases MMP, having formula (I) below wherein R, R1, R2, R3, R4, R5, n and m have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of degenerative disorders.
US08329750B2 Methods for treating vasomotor symptoms using GABA analogs in a gastric retentive dosage form
Methods for treating vasomotor symptoms associated with menopause are described.
US08329739B2 Phenylimidazole compounds
[Object] To provide a pharmaceutical product (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, etc.[Solving Means] A phenylimidazole compound represented by the following General Formula (1): wherein, R1 represents a hydrogen atom, a phenyl lower alkyl group optionally having a substituent, or a pyridyl lower alkyl group optionally having a substituent, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted lower alkyl groups. One of R2 and R3 represents a hydrogen atom and the other represents a lower alkoxy group. R4 represents a phenyl group optionally having a substituent. R5 and R6 are the same or different, and represent a hydrogen atom or a lower alkyl group. R7 and R8 are the same or different, and represent a hydrogen atom or a lower alkoxy group. However, when R1 represents an unsubstituted phenyl lower alkyl group, R2 represents a lower alkoxy group, R3 represents a hydrogen atom, R4 represents a phenyl group optionally having a substituent, and R5 represents a hydrogen atom, R6 is not a hydrogen atom.
US08329734B2 Topical therapy for migraine
The invention is directed to formulations and methods of treating a migraine and/or cluster headache with a serotonin agonist, pharmaceutically acceptable salt thereof, or derivative thereof.
US08329733B2 Composition for noxious organisms-controlling agent and method for using the same
The present invention relates to a composition for noxious organisms-controlling agent having a synergistic effect and a method for using said composition, which comprises, as active ingredients thereof, one or more compounds selected from the phthalamide derivatives represented by general formula (I) being useful as an insecticide or acaricide and one or more compounds selected from the compounds having insecticidal, acaricidal or nematocidal activity: wherein R1, R2 and R3 may be the same or different and each represent hydrogen atom, C3-C6 cycloalkyl, -A1-Qp, etc., each of X and Y may be the same or different and represents hydrogen atom, halogen atom, etc., n is an integer of 1 to 4, m is an integer of 1 to 5, and each of Z1 and Z2 represents O or S.
US08329732B2 Kinase inhibitors and methods of their use
New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer.
US08329727B2 Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
US08329725B2 Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
The invention relates to annelated pyrrolidin sulfonamides with oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula (I), in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
US08329724B2 Process for the manufacture of pharmaceutically active compounds
According to the present invention there are provided novel processes for the manufacture of the compound of formula 1 as well as novel synthesis routes for key intermediates used in those processes.
US08329722B2 Inhibitors of janus kinases and/or 3-phosphoinositide-dependent protein kinase-1
The instant invention provides for compounds that inhibit JAK2 tyrosine kinase and/or PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting JAK2 tyrosine kinase activity and/or PDK1 kinase inhibitory activity by administering the compound to a patient in need of treatment or prevention of myeloproliferative disorders or cancer.
US08329718B2 N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
US08329717B2 Pyrimidine derivatives and their use for controlling undesired plant growth
Compounds of the formula (I) and their agrochemically compatible salts and their use in the field of crop protection are described.
US08329715B2 Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to rheumatoid arthritis.
US08329712B2 Heterocyclic antiviral compounds
Compounds having the formula I wherein R1, R2, R3 and X are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
US08329709B2 5H-cyclopenta[D]pyrimidines as AKT protein kinase inhibitors
Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).
US08329708B2 1,3,6-substituted indole derivatives having inhibitory activity for protein kinase
Disclosed are a 1,3,6-substituted indole compound having inhibitory activity for protein kinases, a pharmaceutically acceptable thereof, and a pharmaceutical composition for prevention and treatment of diseases caused by abnormal cell growth including the compound as an active ingredient.Since the novel indole compound exhibits superior inhibitory activity for various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating cancers caused by abnormal cell growth.
US08329699B2 Pyrrolopyrazine kinase inhibitors
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R1 and R2 are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
US08329695B2 Crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7r)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide
The present invention relates to a crystalline form a dihydropteridione derivative, namely a crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.
US08329691B2 Amide compounds and use of the same
A renin inhibitor comprising a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof. The compound of the present invention has a superior renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
US08329690B2 Cyclothiocarbamate derivatives as progesterone receptor modulators
Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: wherein R1, R2, R3, R4, R5, and Q1 are defined herein.
US08329687B2 Pyridooxazepine derivative and use thereof
The present invention provides a compound having a superior serotonin 5-HT2C receptor activating action, which is represented by the formula wherein A is —OR1 or —S(O)pR2, R1 and R2 are the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group to optionally having substituent(s), and p is 0, 1 or 2, or a salt thereof.
US08329679B2 Preformulation for tabletting natural mixtures of conjugated estrogens
A method of producing a pharmaceutical preformulation in the form of a solid, free-flowing dry extract of a natural mixture of conjugated equine estrogens, which is particularly suitable use in for solid galenic forms, e.g. tabletting. The conjugated estrogens are available for further galenic processing in a form which assures the chemical stability of the hormones and permits advantageous processing into solid galenic forms, for example a tablet.
US08329678B1 Antiinflammatory compound
Azadirachta indica cell suspension culture was used for the biotransformation of dianabol to yield a metabolite 17β-hydroxy-17α-methyl-5α-androstan-3-one, which can also be synthesized, as a potent antiinflammatory agent.
US08329677B2 Method of treating and preventing secondary hyperparathyroidism
The a method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering, as necessary, both Vitamin D repletion and Vitamin D hormone replacement therapies, is disclosed. The blood concentrations of 25-hydroxyvitamin D are increased to and maintained at or above 30 ng/mL, and blood concentrations of 1,25-dihydroxyvitamin D are increased to or maintained within a patient's normal historical physiological range for 1,25-dihydroxyvitamin D without causing substantially increased risk of hypercalcemia, hyperphosphatemia or over suppression of plasma iPTH in the patient. The blood levels of 25-hydroxyvitamin D are maintained at or above 30 ng/mL between doses of Vitamin D repletion therapies, and the blood levels of 1,25-dihydroxyvitamin D are maintained in the patient's normal historical physiological range between doses of Vitamin D hormone replacement therapies. In one aspect, the disclosure includes methods wherein the blood concentration of 25-hydroxyvitamin D during treatment comprises predominantly 25-hydroxyvitamin D3, and/or wherein the method includes administering predominantly or solely 25-hydroxyvitamin D3 for 25-hydroxyvitamin D repletion and/or maintenance.
US08329676B2 Cycloalkane-containing sphingosine 1-phosphate agonists
The present invention provides sphingosine-1-phosphate analogs that are potent, and selective agonists at one or more S1P receptors, specifically the S1P1 receptor type, which alter lymphocyte trafficking. The compounds of the invention include compounds having a phosphate moiety as well as compounds with hydrolysis-resistant phosphate surrogates such as phosphonates, alpha-substituted phosphonates, and phosphothionates.
US08329671B2 Reduction of dermal scarring
Methods and compositions for reducing or inhibiting dermal scarring by expressing p21WAF1/Cip1 in a wound site are provided.
US08329670B2 System for delivering nucleic acids for suppressing target gene expression by utilizing endogenous chylomicron
The object of present invention is to provide a system that can deliver in vivo nucleic acids such as an siRNA for suppressing a target gene expression in vivo more safely and efficiently, and to provide an expression-suppressing agent and a pharmaceutical composition utilizing the system. An introduction substance into chylomiclon, particularly nucleic acids to which an alpha-tocopherol is bound for suppressing a target gene expression, can be delivered more safely and efficiently into hepatic cells in vivo by administering the nucleic aids under the condition where the production of chylomicron is induced in the body. Alternatively, alpha-tocopherol-bound nucleic acids are mixed with extracted chylomiclon, and then they are administered. Consequently, a target gene expression is suppressed, thereby a disease caused by an elevated expression of the target gene can be treated more safely and efficiently.
US08329668B2 Antisense antiviral compound and method for treating picornavirus infection
The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Picornaviridae family and in the treatment of a viral infection. The compounds are particularly useful in the treatment of Enterovirus and/or Rhinovirus infection in a mammal. The antisense antiviral compounds are substantially uncharged, including partially positively charged, morpholino oligonucleotides have a sequence of 12-40 subunits, including at least 12 subunits having a targeting sequence that is complementary to a region associated with viral RNA sequences within a 32 nucleotide region of the viral 5′ untranslated region identified by SEQ ID NO:4.
US08329666B2 Compositions and methods for treating cancer
Provided herein are methods of treating cancer comprising administering decitabine in combination with compounds that inhibit the deamination enzyme responsible for the inactivation of decitabine.
US08329663B2 Compositions and methods for the treatment of chronic infections
The present disclosure provides compositions and methods for the treatment and elimination of chronic intracellular infections in cells or organisms. The compositions may include one or more acidic substances and one or more antimicrobial substances, administered in combination or separately. The methods may include administering an amount of one or more such compositions to an infected cell or organism for a period of time ranging from days to years, until the infection is substantially eliminated.
US08329661B2 Method for using HIP/PAP polypeptide composition for liver regeneration and prevention of liver failure
This invention is based on the experimental finding that HIP/PAP has mitogenic and antiapoptotic effects in vitro on hepatocytes in primary culture. Moreover, HIP/PAP is a mitogenic and anti-apoptotic molecule for hepatocytcs, in vivo, during liver failure and liver regeneration. The present invention is also based on the experimental finding that HIP/PAP administration has no adverse effects in mammals. This invention concerns a pharmaceutical composition for stimulating liver regeneration in vivo including after chronic/acute liver failure, comprising an effective amount of a polypeptide comprising an amino acid sequence having 90% amino acid identity with the polypeptide consisting of the amino acid sequence starting at the amino acid residue (36) and ending at the amino acid residue (175) of sequence SEQ ID No 1, in combination with at least one physiologically acceptable excipient.
US08329659B2 SAP variants and their use
Polypeptides are susceptible to denaturation or enzymatic degradation in the blood, liver or kidney. Due to the low stability of some polypeptides, it has been required to administer polypeptide drugs in a sustained frequency to a subject in order to maintain an effective plasma concentration of the active substance. Furthermore, pharmaceutical compositions of therapeutic peptides preferably have a shelf-life of several years in order to be suitable for common use. However, peptide compositions are inherently unstable due to sensitivity towards chemical and physical degradation. In part, the invention provides SAP variant proteins, compositions, pharmaceutical preparations and formulations having a prolonged in vivo half-life, prolonged shelf-life, or rather increased in vitro stability, or increased manufacturing efficiency compared to human SAP. Advantages of increased plasma half-life include, but are not limited to, reducing the amount and/or frequency of dosing.
US08329658B2 Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
This invention provides compounds of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus and/or human immunodeficiency virus.
US08329657B2 Fn14/TRAIL fusion proteins and method of treating cancer
Fusion proteins which act on the TWEAK and TRAIL signaling axes are provided. The proteins are useful in the treatment or amelioration of autoimmune diseases, particularly multiple sclerosis, as well as other diseases such as alloimmune diseases and cancer.
US08329647B2 Method of treating a subject according to biomarkers for insulin resistance
The invention provides compositions and methods for determining insulin resistance and/or pancreatic β-cell dysfunction in a subject. The invention also provides compositions and methods for treating a subject according to the insulin resistance and/or pancreatic β-cell dysfunction in the subject.
US08329643B2 PIMAP39 modulates LPS-induced inflammatory response
The present invention relates to a novel peptide sequence named PIMAP39 (herein referred to as SEQ ID NO.: 1) and methods of use of the novel sequence and functional variants thereof. The present invention also relates to methods for reducing and/or modulating inflammatory responses by administration of the peptide of the present invention. Furthermore, the present invention relates to the modulation of the expression of cytokines effected as part of an inflammatory response by administration of the peptide of the present invention.
US08329642B1 Formula and method to enhance external physiognomy
The present invention is directed to nutritional compositions for systemic ingestion that improve the overall appearance, or physiognomy, of a person, and to methods of use of such compositions. In one aspect of the present invention, the nutritional composition comprises highly available nutritional oils and peptides/proteins that are known to enhance hair, skin, and nails. In another aspect of the present invention, the nutritional composition comprises a powder that is dispersible in a liquid dispersion or emulsion. In another aspect of the present invention, the nutritional composition is a liquid dispersion or emulsion. In another aspect of the present invention, the method of use of the nutrient composition comprises dispersing a dose of 20 grams of the composition in the form of a powder into a liquid of choice, followed by stirring and swallowing of the liquid.
US08329637B2 Method for the treatment of automimmune diseases comprising administering rapamycin and IL-10
The invention discloses a combined preparation containing IL-10 and rapamycin, able to induce immunosuppression and antigen-specific immune tolerance, and the use thereof in the treatment of diseases involving an excessive, dysfunctional or uncontrolled immune responses mediated by T cells.
US08329636B2 Carcinoma diagnosis and treatment, based on ODC1 genotype
The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other invasive cancers where cellular proliferation and carcinogenesis is linked, in part, to high levels of ODC activity and increased cellular polyamine contents, and b) for selecting the corresponding treatment options for such patients based on the allelic nucleotide sequence or SNP at position +316 of the ODC1 promoter gene as well as cancer treatment methods, in each case, which include the determination of the ODC1 promoter +316 position genotype, as a means to guide treatment selection.
US08329635B2 Method for the preparation of specific antibodies against saccharidic antigens
The present invention relates to new compounds useful for the stimulation of the production of antibodies. Said compounds comprises a saccharidic tumor antigen and a polymeric scaffold. The present invention also encompasses conjugated compounds useful in ELISA assay for the selection of antibodies against saccharidic antigens.
US08329634B2 Water based paint thinner
A paint thinner and cleaner includes a methyl soy ester and dibasic ester and satisfies a less than 25 grams per liter Volatile Organic Compound (VOC) rating which permits the thinner and cleaner to be used for cleaning and thinning in government regulated areas. Requirements for reducing VOCs are well recognized. The paint thinner and cleaner of the present invention performs as well as products (for example, hydrocarbon based thinners) having greater than 25 grams per liter VOC products. Further, the paint thinner and cleaner according to the present invention has less than one tenth of the hazardous ingredients present in the other paint thinners. The paint thinner and cleaner is suitable for reducing water and oil based coatings and material.
US08329633B2 Poly quaternary functionalized alkyl polyglucosides for enhanced food soil removal
A cleaning composition including a poly quaternary functionalized alkyl polyglucoside, a water conditioning agent, an acid source, a solvent, and water. In one embodiment, the cleaning composition is substantially free of alkyl phenol ethoxylates. The cleaning composition is capable of removing soils including up to 20% proteins. The cleaning compositions include a biorenewable, environmentally friendly alternative to nonyl phenol ethoxylates and exhibit superior cleaning of food soils.
US08329632B2 Detergent compositions and the use of enzyme combinations therein
New detergent compositions and the use of enzyme combinations therein are disclosed. The compositions have enhanced stability of non protease enzymes present in the compositions.
US08329631B2 Hand dishwashing detergent
An aqueous cleaning agent for hard surfaces which contains a surfactant combination of fatty alcohol ether sulfate and at least one further surfactant together with 10 to 40 wt. % of a water-soluble salt, may be used for manual dishwashing and is above all suitable for removing stubborn, burnt-on or dried-on soiling while being gentle on the skin.
US08329626B2 Low-irritating, clear cleansing compositions with relatively low pH
The methods and compositions of this invention relate to compositions having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin.
US08329622B2 Alcohol compatible copolymer
Alcohol compatible, water-soluble copolymer useful as a corrosion inhibitor. The copolymer includes at least one olefinically unsaturated carboxylic acid monomer, at least one olefinically unsaturated mono- or di-alkyl ester of a di-carboxylic acid monomer, and at least one olefinically unsaturated hydrophilic, non-ionic monomer. The molar ratio of the alkyl ester groups of the mono- or di-alkyl ester of the dicarboxylic acid monomer to the hydrophilic groups of the hydrophilic, non-ionic monomers is from about 0.01:1 to 1000:1, and the molar ratio of the sum of the alkyl ester groups and hydrophilic groups of the hydrophilic, non-ionic monomers to the carboxylic acid groups, is from about 0.001:1 to 100:1. No haze or precipitate occurs in a mixture of the water-soluble copolymer at 4° C. for 15 hrs or more as a 20 weight % aqueous copolymer solution in alcohol at a water-soluble copolymer to methanol weight-ratio of not more than 25 to 100.
US08329621B2 Degradable particulates and associated methods
Methods that include a method comprising: providing a degradable polymer, a viscosifier, and one solvent; combining the degradable polymer and the solvent to form a degradable polymer composition; allowing the degradable polymer to at least partially plasticize; and applying sufficient shear to the degradable polymer composition so that degradable particulates begin to form. Additional methods are also provided.
US08329617B2 Compositions and methods for synergistic manipulation of plant and insect defenses
This invention relates to the control of plant pests, such as aphid and whitefly by treating plants with a compound which inhibits the plant pest's ability to overcome plant defense responses, such as piperonyl butoxide or propyl gallate, in combination with a compound which activates plant defense responses, such as cis-Jasmone or beta-amino butyric acid.
US08329616B2 Image receiver elements with overcoat
An image receiving element has an extruded compliant layer, an extruded image receiving layer, and a topcoat immediately adjacent the extruded image receiving layer. The extruded image receiving layer is non-crosslinked and has a glass transition temperature (Tg) of from about 40° C. to about 80° C. whereas the topcoat is an aqueous-coated layer and has a Tg that is within a range of plus or minus 10° C. of the Tg of the extruded image receiving layer. The dry thickness ratio of the topcoat to the extruded image receiving layer is from 1:2 to 1:20.
US08329615B2 Image formation method using thermal transfer sheet and thermal transfer image-receiving sheet
A method of image formation comprising putting a thermal transfer sheet and a thermal transfer image-receiving sheet one upon another wherein the thermal transfer sheet has on a substrate film a subbing layer of a titanium oxide film, the dye layer on a part of the subbing layer and a transferable protective layer laminate on the other part of the subbing layer than the part for the dye layer thereon, and wherein the thermal transfer image-receiving sheet has on a support the receiving layer containing a polymer latex, in which vinyl chloride is polymerized in at least 95 mol % of all the polymerization monomers, and a polyether-modified silicone, and a heat-insulating layer; recording an image on the receiving layer by a heating device; and transferring at least a part of the transferable protective layer laminate onto the receiving layer by the heating device.
US08329614B2 Mercury adsorbents compatible as cement additives
Solid adsorbents, following their use for mercury removal from flue gas, that do not interfere with the ability of air-entraining additives (such as surfactants) to form stable bubbles when added to fly ash containing the adsorbents. The interference is overcome by heating the materials used in the manufacture of the adsorbent so that magnesium hydroxide and/or one or more alkali compounds containing one or more silicate, aluminate, and/or phosphate moiety, added or already present in the materials, binds multivalent cations present in the materials that could otherwise interfere with the surfactant activity.
US08329613B2 Supported gold catalyst
The invention relates to methods for producing supported gold catalysts from a porous metal oxide support and a chloroauric acid precursor, wherein the support is placed in contact with the aqueous solution of the chloroauric acid precursor. The invention also relates to a metal oxide supported gold catalyst and its use in the oxidation of alcohols, aldehydes, polyhydroxy compounds and carbohydrates.
US08329609B2 Process for preparing alkoxylation catalyst and alkoxylation process
A process for preparing an alkoxylation catalyst wherein a catalyst precursor which is formed from an alkoxylated alcohol and an alkaline earth metal compound to form a dispersion of an alkaline earth metal species is reacted with propylene oxide to propoxylate at least a portion of the ethoxylated alcohol.
US08329603B2 Isoparaffin-olefin alkylation
A composition comprising a base component and a polymer, and a method of making said composition, are disclosed. The composition thereby obtained is then used as a catalyst for isoparaffin-olefin alkylation.
US08329599B2 Method of depositing dielectric film by ALD using precursor containing silicon, hydrocarbon, and halogen
A method of forming a dielectric film having at least Si—N, Si—C, or Si—B bonds on a semiconductor substrate by atomic layer deposition (ALD), includes: adsorbing a precursor on a surface of a substrate; supplying a reactant gas over the surface; reacting the precursor and the reactant gas on the surface; and repeating the above steps to form a dielectric film having at least Si—N, Si—C, or Si—B bonds on the substrate. The precursor has at least one Si—C or Si—N bond, at least one hydrocarbon, and at least one halogen attached to silicon in its molecule.
US08329598B2 Sacrificial nitride and gate replacement
Methods of forming a top oxide around a charge storage material layer of a memory cell and methods of improving quality of a top oxide around a charge storage material layer of a memory cell are provided. The method can involve providing a charge storage layer on a semiconductor substrate, a nitride layer on the charge storage layer, and a first poly layer on the nitride layer, and converting at least a portion of the nitride layer to a top oxide. By converting at least a portion of a nitride layer to a top oxide layer, the quality of the resultant top oxide layer can be improved.
US08329596B2 Plasma CVD method, method for forming silicon nitride film and method for manufacturing semiconductor device
A plasma processing apparatus generates plasma by introducing microwaves into a processing chamber by using a planar antenna having a plurality of slots. By using the plasma processing apparatus, a nitrogen containing gas and a silicon containing gas introduced into the processing chamber are brought into the plasma state, and at the time of depositing by using the plasma a silicon nitride film on the surface of the a substrate to be processed, stress to the silicon nitride film to be formed is controlled by the combination of the type and the processing pressure of the nitrogen containing gas.
US08329592B2 Method of fabricating semiconductor device, and photomask
A method of fabricating a semiconductor device according to one embodiment includes: forming a mask material on a semiconductor substrate comprising first and second regions; forming a pattern of a core on the mask material in the first region; forming a sidewall spacer mask on a side surfaces of the core pattern and subsequently removing the core pattern; transferring a pattern of the sidewall spacer mask to the mask material in the first region after removing the core; and thereafter, carrying out trimming of the pattern of the sidewall spacer mask which is transferred to the mask material in the first region, and formation of a predetermined pattern on the mask material in the second region, simultaneously.
US08329591B2 Method of manufacturing a semiconductor device
Disclosed is a means for stabilizing quality of a semiconductor device by preventing projections from being formed in the bottom of a through hole. A method of manufacturing a semiconductor device includes a process of forming a through hole reaching a metal nitride layer through an interlayer insulating layer on a semiconductor wafer on which the wiring layer, the metal nitride layer formed on the wiring layer, and the interlayer insulating layer covering the wiring layer and the metal nitride layer are formed. The through hole forming process includes: a first etching step of etching the interlayer insulating layer by an anisotropic etching method with the semiconductor wafer set to a first temperature; and a second etching step of etching an upper surface of metal nitride layer by an anisotropic etching method with the semiconductor wafer set to a second temperature higher than the first temperature.
US08329590B2 Plasma processing apparatus and methods for removing extraneous material from selected areas on a substrate
Apparatus and methods for shielding a feature projecting from a first area on a substrate to a plasma while simultaneously removing extraneous material from a different area on the substrate with the plasma. The apparatus includes at least one concavity positioned and dimensioned to receive the feature such that the feature is shielded from the plasma. The apparatus further includes a window through which the plasma removes the extraneous material. The method generally includes removing the extraneous material while shielding the feature against plasma exposure.
US08329589B2 Semiconductor device with gate-undercutting recessed region
A semiconductor device comprises a gate structure on a semiconductor substrate and a recessed region in the semiconductor substrate. The recessed region has a widest lateral opening that is near a top surface of the semiconductor substrate. The widest lateral opening undercuts the gate structure.
US08329578B2 Via structure and via etching process of forming the same
A via etching process forms a through-substrate via having a round corner and a tapered sidewall profile. A method includes providing a semiconductor substrate; forming a hard mask layer and a patterned photoresist layer on the semiconductor substrate; forming an opening in the hard mask and exposing a portion of the semiconductor substrate; forming a via passing through at least a part of the of semiconductor substrate using the patterned photoresist layer and hard mask layer as a masking element; performing a trimming process to round the top corner of the via; and removing the photoresist layer.
US08329577B2 Method of forming an alloy in an interconnect structure to increase electromigration resistance
By introducing a metallic species into an exposed surface area of a copper region, the electromigration behavior of this surface area may be significantly enhanced. The incorporation of the metallic species may be accomplished in a highly selective manner so as to not unduly affect dielectric material positioned adjacent to the metal region, thereby essentially avoiding undue increase of leakage currents.
US08329576B2 Method for improving uniformity and adhesion of low resistivity tungsten film
Methods of improving the uniformity and adhesion of low resistivity tungsten films are provided. Low resistivity tungsten films are formed by exposing the tungsten nucleation layer to a reducing agent in a series of pulses before depositing the tungsten bulk layer. According to various embodiments, the methods involve reducing agent pulses with different flow rates, different pulse times and different interval times.
US08329575B2 Fabrication of through-silicon vias on silicon wafers
A through-silicon via fabrication method includes etching a plurality of through holes in a silicon plate. An oxide liner is deposited on the surface of the silicon plate and on the sidewalls and bottom wall of the through holes. A metallic conductor is then deposited in the through holes. In another version, which may be used concurrently with the oxide liner, a silicon nitride passivation layer is deposited on the exposed back surface of the silicon plate of the substrate.
US08329572B2 Semiconductor device and method for fabricating the same
In a method for fabricating a semiconductor device, first, a first metal interconnect is formed in an interconnect formation region, and a second metal interconnect is formed in a seal ring region. Subsequently, by chemical mechanical polishing or etching, the upper portions of the first metal interconnect and the second metal interconnect are recessed to form recesses. A second insulating film filling the recesses is then formed above a substrate, and the upper portion of the second insulating film is planarized. Next, a hole and a trench are formed to extend halfway through the second insulating film, and ashing and polymer removal are performed. Subsequently to this, the hole and the trench are allowed to reach the first metal interconnect and the second metal interconnect.
US08329567B2 Methods of forming doped regions in semiconductor substrates
Some embodiments include methods of forming one or more doped regions in a semiconductor substrate. Plasma doping may be used to form a first dopant to a first depth within the substrate. The first dopant may then be impacted with a second dopant to knock the first dopant to a second depth within the substrate. In some embodiments the first dopant is p-type (such as boron) and the second dopant is neutral type (such as germanium). In some embodiments the second dopant is heavier than the first dopant.
US08329560B2 Laser processing apparatus and method using beam split
Disclosed are a laser processing apparatus and method that can effectively remove a low-k material formed on a wafer. A laser processing apparatus of the invention is a laser processing apparatus that processes a subject on which a low-k material is formed. The laser processing apparatus includes a laser generating unit that emits a laser beam; and an optical system that splits the laser beam emitted from the laser generating unit into two and irradiates the split laser beams onto the subject In this case, the optical system includes a pair of condensing lenses in which cut surfaces that are cut at a predetermined distance from central axes to be parallel to the central axes contact with each other, and the interval between the two split laser beams is the same as the interval between two edges of the low-k material in a removal subject region. According to the invention, after splitting a laser beam into two laser beams and primarily removing the edges of the low-k material in the removal subject region using the laser beams, the remaining low-k material between the edges is removed. As a result, it is possible to improve processing quality.
US08329557B2 Techniques for forming thin films by implantation with reduced channeling
Embodiments of the present invention relate to the use of a particle accelerator beam to form thin films of material from a bulk substrate. In particular embodiments, a bulk substrate having a top surface is exposed to a beam of accelerated particles. Then, a thin film of material is separated from the bulk substrate by performing a controlled cleaving process along a cleave region formed by particles implanted from the beam. To improve uniformity of depth of implantation, channeling effects are reduced by one or more techniques. In one technique, a miscut bulk substrate is subjected to the implantation, such that the lattice of the substrate is offset at an angle relative to the impinging particle beam. According to another technique, the substrate is tilted at an angle relative to the impinging particle beam. In still another technique, the substrate is subjected to a dithering motion during the implantation. These techniques may be employed alone or in combination.
US08329552B1 Semiconductor device and method of manufacture
A system and method for forming an isolation trench is provided. An embodiment comprises forming a trench and then lining the trench with a dielectric liner. Prior to etching the dielectric liner, an outgassing process is utilized to remove any residual precursor material that may be left over from the deposition of the dielectric liner. After the outgassing process, the dielectric liner may be etched, and the trench may be filled with a dielectric material.
US08329548B2 Field transistors for electrostatic discharge protection and methods for fabricating the same
A field transistor for electrostatic discharge (ESD) protection and method for making such a transistor is described. The field transistor includes a gate conductive layer pattern formed on a field oxide layer. Since the gate conductive layer pattern is formed on the field oxide layer, a thin gate insulating layer having a high possibility of insulation breakdown is not used. To form an inversion layer for providing a current path between source and drain regions, a field oxide layer is interposed to form low concentration source and drain regions overlapped by the gate conductive layer pattern.
US08329544B2 Method for forming a semiconductor device having nanocrystals
A method is provided for forming a semiconductor device having nanocrystals. The method includes: forming a first insulating layer over a surface of a substrate; forming a first plurality of nanocrystals on the first insulating layer; implanting a first material into the first insulating layer; and annealing the first material to form a second plurality of nanocrystals in the first insulating layer. The method may be used to provide a charge storage layer for a non-volatile memory having a greater nanocrystal density.
US08329543B2 Method for forming a semiconductor device having nanocrystals
A method is provided for forming a semiconductor device having nanocrystals. The method includes: providing a substrate; forming a first insulating layer over a surface of the substrate; forming a first plurality of nanocrystals on the first insulating layer; forming a second insulating layer over the first plurality of nanocrystals; implanting a first material into the second insulating layer; and annealing the first material to form a second plurality of nanocrystals in the second insulating layer. The method may be used to provide a charge storage layer for a non-volatile memory having a greater nanocrystal density.
US08329536B2 Method for manufacturing semiconductor device with silicon nitride charge trapping film having varying hydrogen concentration
To improve a charge retention characteristic of a nonvolatile memory transistor. A first insulating film, a charge trapping film, and a second insulating film are formed between a semiconductor substrate and a conductive film. The charge trapping film is formed of a silicon nitride film including an upper region having a low concentration of hydrogen and a lower region having a high concentration of hydrogen. Such a silicon nitride film is formed in such a manner that a silicon nitride film including 15 atomic % or more hydrogen is formed by a chemical vapor deposition method and an upper portion of the silicon nitride film is nitrided. The nitridation treatment is performed by nitriding the silicon nitride film by nitrogen radicals produced in plasma of a nitrogen gas.
US08329535B2 Multi-level-cell trapping DRAM
A memory device having at least one multi-level memory cell is disclosed, and each multi-level memory cell configured to store n multiple bits, where n is an integer, wherein the multiple bits are stored in a charge storage layer trapping charge carriers injected by application of a voltage to set or reset a threshold voltage Vt of the memory cell to one of 2n levels. Each memory cell may be programmed to one of 2n multiple levels, wherein each level represents n multiple bits.
US08329530B1 Method and system for providing contact to a first polysilicon layer in a flash memory device
A method and system for providing at least one contact in a flash memory device is disclosed. The flash memory device includes a plurality of gate stacks and at lease one component including a polysilicon layer as a top surface. The method and system further include forming a silicide on the top surface of the polysilicon layer and providing an insulating layer covering the plurality of gate stacks, the at least one component and the silicide. The method and system also include etching the insulating layer to provide at least one contact hole. The insulating layer etching step uses the silicide as an etch stop layer to ensure that the insulating etching step does not etch through the polysilicon layer. The method and system also include filling the at least one contact hole with a conductor.
US08329529B2 Via contact structures and methods for integrated circuits
A method for fabricating an integrated circuit device includes providing a semiconductor substrate having a first region and a second region, e.g., peripheral region. The method forms a stop layer overlying the first and second regions and a low k dielectric layer (e.g., k<2.9) overlying the stop layer in the first and second regions. The method forms a cap layer overlying the low k dielectric layer. In an embodiment, the method initiates formation of a plurality of via structures within a first portion of the low k dielectric layer overlying the first region and simultaneously initiates formation of an isolated via structure for in the second region of the semiconductor substrate, using one or more etching processes. The method includes ceasing formation of the plurality of via structures within the first portion and ceasing formation of the isolated via structure in the second region when one or more portions of stop layer have been exposed.
US08329525B2 Method for fabricating at least three metal-oxide semiconductor transistors having different threshold voltages
At least three metal-oxide semiconductor transistors with different threshold voltages are formed in and above corresponding first, second and third parts of a semiconductor substrate. The second transistor has a lower threshold voltage than the second transistor, and the third transistor has a lower threshold voltage than the second transistor. The gate oxide layers for the three transistors are formed as follows: a first oxide layer having a first thickness is formed above the first, second and third parts. The first oxide layer above the second part is etched and a second oxide layer having a second thickness smaller than the first thickness is formed. The first oxide layer above the third part is etched and a third oxide layer having a third thickness smaller than the second thickness is formed. The second and the third oxide layers are then nitrided to form first and second oxy-nitride layers.
US08329523B2 Array substrate for dislay device and method of fabricating the same
A method of fabricating an array substrate for a display device includes: forming a buffer layer on a substrate having a pixel region; sequentially forming a gate electrode of impurity-doped polycrystalline silicon, a gate insulating layer and an active layer of intrinsic polycrystalline silicon on the buffer layer in the pixel region; forming an interlayer insulating layer of an inorganic insulating material on the active layer; sequentially forming a source barrier pattern, a source ohmic contact layer and a source electrode on the interlayer insulating layer, sequentially forming a drain barrier pattern, a drain ohmic contact layer and a drain electrode on the interlayer insulating layer, and sequentially forming a first dummy pattern, a second dummy pattern and a data line on the interlayer insulating layer; forming a first passivation layer on a surface of the interlayer insulating layer including the source electrode, the drain electrode and the data line formed thereon; forming a gate line on the first passivation layer; forming a second passivation layer on a surface of the first passivation layer including the gate line formed thereon; and forming a pixel electrode on the second passivation layer.
US08329521B2 Method and device with gate structure formed over the recessed top portion of the isolation structure
A method includes providing a substrate having a first surface, forming an isolation structure disposed partly in the substrate and having an second surface higher than the first surface by a step height, removing a portion of the isolation structure to form a recess therein having a bottom surface spaced from the first surface by less than the step height, forming a gate structure, and forming a contact engaging the gate structure over the recess. A different aspect involves an apparatus that includes a substrate having a first surface, an isolation structure disposed partly in the substrate and having a second surface higher than the first surface by a step height, a recess extending downwardly from the second surface, the recess having a bottom surface spaced from the first surface by less than the step height, a gate structure, and a contact engaging the gate structure over the recess.
US08329519B2 Methods for fabricating a semiconductor device having decreased contact resistance
Semiconductor devices having improved contact resistance and methods for fabricating such semiconductor devices are provided. These semiconductor devices include a semiconductor device structure and a contact. The contact is electrically and physically coupled to the semiconductor device structure at both a surface portion and a sidewall portion of the semiconductor device structure.
US08329517B2 Pixel structure and method for manufacturing the same
A method for manufacturing a pixel structure includes providing a substrate including a transistor region and a pixel region, forming at least one gate electrode on the transistor region, forming an insulating layer on the substrate to overlay the gate electrode, and forming a patterned semi-conductive layer on the surface of a portion of the insulating layer disposed on the transistor region and the pixel region. A patterned first protective layer is formed on a portion of the patterned semi-conductive layer corresponding to the gate electrode, and the patterned semi-conductive layer is doped without being overlaid by the patterned first protective layer.
US08329515B2 eFUSE enablement with thin polysilicon or amorphous-silicon gate-stack for HKMG CMOS
An eFUSE is formed with a gate stack including a layer of embedded silicon germanium (eSiGe) on the polysilicon. An embodiment includes forming a shallow trench isolation (STI) region in a substrate, forming a first gate stack on the substrate for a PMOS device, forming a second gate stack on an STI region for an eFUSE, forming first embedded silicon germanium (eSiGe) on the substrate on first and second sides of the first gate stack, and forming second eSiGe on the second gate stack. The addition of eSiGe to the eFUSE gate stack increases the distance between the eFUSE debris zone and an underlying metal gate, thereby preventing potential shorting.
US08329513B2 Methods of forming a memory array with a pair of memory-cell strings to a single conductive pillar
A method of forming a memory array includes forming first and second strings of serially-coupled memory cells respectively on first and second sides of a conductive pillar. Forming the first string of memory cells includes forming a first control gate on the first side of the conductive pillar and interposing a first charge trap between the first side of the conductive pillar and the first control gate. Forming the second string of memory cells comprises forming a second control gate on the second side of the conductive pillar and interposing a second charge trap between the second side of the conductive pillar and the second control gate. The first and second charge traps are electrically isolated from each other, and the first and second control gates are electrically isolated from each other.
US08329507B2 Semiconductor package, integrated circuit cards incorporating the semiconductor package, and method of manufacturing the same
One embodiment of a semiconductor package described herein includes a substrate having a first through-hole extending therethrough; a conductive pattern overlying the substrate and extending over the first through-hole; a first semiconductor chip facing the conductive pattern such that at least a portion of the first semiconductor chip is disposed within the first through-hole; and a first external contact terminal within the first through-hole and electrically connecting the conductive pattern to the first semiconductor chip.
US08329505B2 Method for deposition of cathodes for polymer optoelectronic devices
Embodiments of the invention explore solution-based deposition of a cathode for an OLED structure. A typical embodiment of the invention may include a method performed according to the following steps: Glass substrates including deposited Indium Tin-Oxide (ITO) are prepared. The substrates are subjected to ultrasonic cleaning with deionized water and organic solvents. Features are etched into the ITO using high concentration HCl solution. A hole injecting layer is deposited by spin coater. The layer is annealed on a hot plate, then a polyphenylene vinylene (PPV) polymer is deposited by spin coater and annealed on a hot plate. Low work function cathode metal is then deposited in an electroless solution and annealed on a hot plate. The device is encapsulated.
US08329502B2 Conformal coating of highly structured surfaces
Method of applying a conformal coating to a highly structured substrate and devices made by the disclosed methods are disclosed. An example method includes the deposition of a substantially contiguous layer of a material upon a highly structured surface within a deposition process chamber. The highly structured surface may be associated with a substrate or another layer deposited on a substrate. The method includes depositing a material having an amorphous structure on the highly structured surface at a deposition pressure of equal to or less than about 3 mTorr. The method may also include removing a portion of the amorphous material deposited on selected surfaces and depositing additional amorphous material on the highly structured surface.
US08329501B1 High-throughput printing of semiconductor precursor layer from inter-metallic microflake particles
Methods and devices are provided for high-throughput printing of semiconductor precursor layer from microflake particles. In one embodiment, the method comprises of transforming non-planar or planar precursor materials in an appropriate vehicle under the appropriate conditions to create dispersions of planar particles with stoichiometric ratios of elements equal to that of the feedstock or precursor materials, even after settling. In particular, planar particles disperse more easily, form much denser coatings (or form coatings with more interparticle contact area), and anneal into fused, dense films at a lower temperature and/or time than their counterparts made from spherical nanoparticles. These planar particles may be microflakes that have a high aspect ratio. The resulting dense film formed from microflakes is particularly useful in forming photovoltaic devices. In one embodiment, at least one set of the particles in the ink may be inter-metallic flake particles (microflake or nanoflake) containing at least one group IB-IIIA inter-metallic alloy phase.
US08329498B2 Method of manufacturing a semiconductor wafer comprising an integrated optical filter
A method manufactures semiconductor chips each comprising a component implanted in the semiconductor. The method includes collectively implanting components onto a front face of a semiconductor wafer and fixing a plate of a transparent material onto the front face of the wafer. Fixing the plate of transparent material is preceded by a step of depositing, on the front face of the wafer, at least one layer of polymer material forming an optical filter. Application is particularly to the manufacturing of imagers.
US08329497B2 Backside illuminated imaging sensor with improved infrared sensitivity
A backside illuminated imaging sensor includes a semiconductor layer and an infrared detecting layer. The semiconductor layer has a front surface and a back surface. An imaging pixel includes a photodiode region formed within the semiconductor layer. The infrared detecting layer is disposed above the front surface of the semiconductor layer to receive infrared light that propagates through the imaging sensor from the back surface of the semiconductor layer.
US08329496B2 Dithered scanned laser beam for scribing solar cell structures
Provided herein are methods of scribing a solar cell structure to create isolated solar cells. The methods involve scanning and high frequency dithering of a laser beam across a solar cell structure such that the beam creates a stepped scribed line profile. In certain embodiments, a structure including an absorber layer sandwich between two contact layers is provided. The scanned dithered laser beam ablates all of these layers on one part of the scribe line while the back contact layer on another part of the scribe line, leaving an exposed back contact layer. The scribe electrically isolates solar cell structures on either side of the scribe line from each other, while providing a contact point to the back contact layer of one of solar cell structure for subsequent cell-cell interconnection.
US08329491B2 Mechanical quantity sensor and method of manufacturing the same
A mechanical quantity sensor includes a first structure having a fixed portion with an opening, a displaceable portion arranged in the opening and displaceable relative to the fixed portion, and a connection portion connecting the fixed portion and the displaceable portion, a second structure having a weight portion joined to the displaceable portion and a pedestal arranged surrounding the weight portion and joined to the fixed portion, the second structure being arranged and stacked on the first structure, a first base connected to the fixed portion and arranged and stacked on the first structure, and a second base connected to the pedestal and arranged and stacked on the second structure. The weight portion is adjusted in thickness after the first structure is made and before the second base and the second structure are joined.
US08329488B2 Method of fabricating semiconductor substrate and method of fabricating light emitting device
The present invention provides a method of fabricating a semiconductor substrate and a method of fabricating a light emitting device. The method includes forming a first semiconductor layer on a substrate, forming a metallic material layer on the first semiconductor layer, forming a second semiconductor layer on the first semiconductor layer and the metallic material layer, wherein a void is formed in a first portion of the first semiconductor layer under the metallic material layer during formation of the second semiconductor layer, and separating the substrate from the second semiconductor layer by etching at least a second portion of the first semiconductor layer using a chemical solution.
US08329487B2 Fabricating method of light emitting diode chip
In a fabricating method of an LED, a first-type doped semiconductor material layer, a light emitting material layer, and a second-type doped semiconductor material layer are sequentially formed on a substrate. The first-type and second-type doped semiconductor material layers and the light emitting material layer are patterned to form a first-type doped semiconductor layer, an active layer, and a second-type doped semiconductor layer. The active layer is disposed on a portion of the first-type doped semiconductor layer. The second-type doped semiconductor layer is disposed on the active layer and has a first top surface. A wall structure is formed on the first-type doped semiconductor layer that is not covered by the active layer, and the wall structure surrounds the active layer and has a second top surface higher than the first top surface of the second-type doped semiconductor layer. Electrodes are formed on the first-type and second-type doped semiconductor layers.
US08329485B2 LED phosphor ink composition for ink-jet printing
The present invention provides an ink jet printable phosphor ink composition for LED packaging that enables precision control of the amount and position of phosphor layers on the LED device or the LED device packaging. The ink includes both a UV-curable resin component and a thermally curable resin component. A phase-separation component prevents phase separation of the UV-curable resin component and the thermally curable resin component. Phosphor particles on the order of less than approximately 2 microns are uniformly dispersed throughout the ink composition. The phosphor ink composition is deposited through either thermal or piezoelectric ink jet printing; a thin layer is deposited in a desired pattern. UV curing (and, optionally, thermal curing) is used to fix each layer followed by subsequent deposition and curing. In this manner, undesirable phosphor settling does not occur and layers are selectively built up to form precise phosphor distributions.
US08329471B2 Isolated population of plant single cells and method of preparing same
This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from cambium or procambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture.
US08329470B2 Labels, containers, system and method for providing reagents
The invention relates to systems and methods for marketing and using products such as liquid materials, especially liquid reagents for use in microbiological and cellular biological laboratory settings include the use of unique color and simple numeric or alphanumeric identifiers to quickly and easily identify any product from a catalog list of products. Methods of marketing, advertising and producing such products are also disclosed. Particular embodiments include products, product packaging and product labeling. The invention also relates to collars and sleeves for containers, as well as related methods of use.
US08329464B2 Implant surface treatment method having tissues integrated
The present disclosure uses different kinds of surface treatment processes on titanium-made dental implants. The growth and attachment conditions of bone cells (MC3T3-E), fibroblasts (NIH 3T3) and epidermal cells (XB-2) on the metal surface of titanium slices with different surface treatments are observed. Tetra-calcium phosphate is used to perform secondary sand-blasting process to clean up the metal surface and provide calcium ions for osteoblastoma physiology. Thus, by adjusting the cells adhesive and proliferative abilities, the success rate of the clinical applications in dental implant is improved.
US08329462B2 Methods and compositions relating to improved lentiviral vectors and their applications
The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise a self-inactivating configuration for biosaftey and promoters such as the EF1α promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element. These vectors therefore provide useful tools for genetic treatments such as inherited and acquired lympho-hematological disorders, gene-therapies for cancers especially the hematological cancers, as well as for the study of hematopoiesis via lentivector-mediated modification of human HSCs.
US08329458B2 Carbonic anhydrase bioreactor and process for CO2 containing gas effluent treatment
A triphasic bioreactor for physico-chemically treating a gas is disclosed. The triphasic bioreactor comprises a reaction chamber with a liquid and biocatalysts in suspension in the liquid, for catalyzing a reaction between the gas and the liquid to obtain a treated gas and a solution containing a reaction product. A gas bubbling means is provided in the reaction chamber for bubbling the gas to be treated into the liquid thereby dissolving the gas into the liquid and increasing a pressure inside the reaction chamber. The bioreactor further comprises a liquid inlet in fluid communication with the reaction chamber for receiving the liquid and filling the reaction chamber, a liquid outlet in fluid communication with the reaction chamber for releasing the solution and a gas outlet in fluid communication with the reaction chamber to release the treated gas. The bioreactor further comprises a retention device to retain the biocatalysts in the reaction chamber. The invention also concerns a process using the triphasic bioreactor. The triphasic bioreactor may advantageously be used for removing carbonic dioxide from a CO2-containing gas.
US08329450B2 Methods and apparatus for organ support
An organ support apparatus includes: (a) a fluid circuit defining upstream and downstream legs adapted to be connected to an organ to be supported; (b) a circulation pump connected to the fluid circuit for circulating a process fluid through the fluid circuit and the organ; and (c) a first waveform generator connected to the fluid circuit for impressing a preselected pressure waveform on the process fluid.
US08329444B2 Strains of zymomonas mobilis for fermentation of biomass
The present invention relates to methods of obtaining Z. mobilis mutant strains that are more tolerant to one or more inhibitors or more capable of efficiently fermenting one or more carbohydrates. Such inhibitors include ethanol, aliphatic acids, such as acetic acid, formic acid; furan derivatives, such as 2-furaldehyde, 2-furoic acid; and phenolic compounds, such as vanillin and hydroxybenzoic acid. Such carbohydrates may include xylose, arabinose, mannose and mixtures thereof. These mutant strains may be employed to, for example, effectively and efficiently prepare ethanol from biomass.
US08329440B2 Lipolytic enzyme ELIP
The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same.
US08329436B2 Method of making propanol and ethanol from plant material by biological conversion and gasification
The invention relates to processes that efficiently convert carbon-containing materials, such as biomass, into products in such a manner that the energy, carbon, and mass content of the materials are efficiently transferred into such products. Such methods include converting the materials into at least one intermediate by a biological conversion process and at least one intermediate by a thermochemical conversion process and reacting the intermediates to form the product. Such methods have a chemical energy efficiency to produce the product that is greater than the chemical energy efficiency of a solely biological conversion process to produce the product and that is greater than the chemical energy efficiency of a process in which all of the material is initially subjected to a thermochemical conversion step as part of the process to produce the product.
US08329435B2 Methods for improved uptake of biological molecules
A “one-step” process for production of peptides and other organic molecules which are both esters and also acetylated forms of the desired molecule. The ester may be a mono-ester, di-ester, or another poly-ester, complexed with a molecule for protecting the organic molecules in the digestive tract. The method allows simple adjustment of the delivery properties of the peptides produced, in particular adjustment or addition of lipiphilic tendencies. A therapeutic or nutrient made by this method comprises acetylated organic molecule esters, in particular an acetylated peptide ester or even an acetylated amino acid ester and demonstrates improved metabolic properties leading to increased efficiency for therapeutic and cosmetic purposes including oral, transdermal, sublingual, buccal, and topical administration. The present disclosure further teaches several specific examples of acetylated esters, including acetyl-glutathione-ester (mGSH), MCAR (carnosine), pyruvate and others modified from base forms by the methods of the present disclosure.
US08329434B2 Enhanced promoter and method for producing L-lysine using the same
The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a transformant transformed with the vector, and a method for producing L-lysine using the transformant.
US08329431B2 Nucleic acid molecules encoding neutralising antibodies having specificity for human IL-17
The invention relates to an antibody molecule having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.
US08329427B2 Method and devices for the cross-referencing of identification of tissue slice supports for microtomised analytical samples
The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).
US08329426B2 High throughput method for measuring total fermentables in small amount of plant part
According to the invention, there is provided a high throughput method for measuring total fermentables using a small amount of plant tissue. A high throughput screening tool for gene discovery aiming for increasing total fermentables is further provided.
US08329425B2 Method and system for detection of chloramphenicol
Fast and simple method of detecting the presence of chloramphenicol, a harmful compound if present in food products. The method makes use of a mutant chloramphenicol acetyltransferase (CAT) and a fluorophore-linked chloramphenicol in a system where chloramphenicol and the fluorophore-linked chloramphenicol competes for the active site of the mutant CAT. Because the fluorophore-linked chloramphenicol reduces its fluorescence upon binding to the active site and vice versa increases its fluorescence upon being displaced from the active site by the presence of unmodified chloramphenicol in a sample, the increase of fluorescence caused by a testing sample indicates the presence of chloramphenicol.
US08329422B2 Analysis of circulating tumor cells, fragments, and debris
The methods and reagents described in this invention are used to analyze circulating tumor cells, clusters, fragments, and debris. Analysis is performed with a number of platforms, including flow cytometry and the CELLSPOTTER® fluorescent microscopy imaging system. Analyzing damaged cells has shown to be important. However, there are two sources of damage: in vivo and in vitro. Damage in vivo occurs by apoptosis, necrosis, or immune response. Damage in vitro occurs during sample acquisition, handling, transport, processing, or analysis. It is therefore desirable to confine, reduce, eliminate, or at least qualify in vitro damage to prevent it from interfering in analysis. Described herein are methods to diagnose, monitor, and screen disease based on circulating rare cells, including malignancy as determined by CTC, clusters, fragments, and debris. Also provided are kits for assaying biological specimens using these methods.
US08329421B2 Methods of predicting response of a neoplasm to an EGFR inhibitor and detecting interactions between EGFR and an EGFR regulatory protein
Disclosed herein are antigen-binding molecules, such as antibodies, that specifically recognize a portion of the EGFR C-terminal (intracellular) regulatory domain that interacts with one or more regulatory molecules (such as Suppressor of Cytokine Signaling (“SOCS”) proteins). In certain normal or neoplastic cells and/or tissues, this region is inaccessible to the disclosed antigen-binding molecules. Thus, such antigen-binding molecules are useful at least to interrogate the regulated state of EGFR, predict the response of a cancer patient to EGFR inhibitor therapies, and/or predict the aggressiveness of neoplasms.
US08329419B2 GLP-1 receptor agonist bioassays
Provided herein are cell-based bioassays for measuring GLP-I receptor agonist activity of test compounds, such as GLP-I receptor agonist compounds. Exemplary GLP-I receptor agonist compounds include exendins, exendin analogs, GLP-1(7-37), and GLP-1(7-37) analogs. The bioassays are useful for quantitatively determining cAMP generated in samples containing GLP-I receptor agonist compounds (e.g., exenatide) and 6-23 (clone 6) cells having GLP-I receptors, whereby the amount of cAMP generated can be correlated to the GLP-I receptor agonist activity of the GLP-I receptor agonist compounds (e.g., exenatide). Suitable cell-based bioassays include enzyme-linked immunosorbent assays and homogeneous time-resolved fluorescence assays.
US08329414B2 Monoclonal antibody and use thereof
The purpose of the invention is to provide an antibody which recognizes OPN N-half but does not recognize the full-length OPN, and its use. A monoclonal antibody which is characterized in that it recognizes a protein or polypeptide in which the C-terminal amino acid sequence is YGLR (SEQ ID NO: 1) and it substantially does not recognize a protein or polypeptide which has an amino acid sequence of YGLR outside of the C-terminal, as well as a method for measuring OPN N-half utilizing the said antibody, a method for diagnosing diseases relating to OPN N-half, a method for judging the severity of said disease, and a method for treating said diseases, are provided.
US08329412B2 Method for determining NAE1-beta or NAE1-beta/NEDD8 complex
The invention relates to covalent modification of proteins through their conjugation with other proteins. More particularly, the invention relates to the modulation of such conjugation involving the protein NEDD8. The invention provides compositions and methods for detecting and/or modulating the activation and/or conjugation of NEDD8, as well as compositions and methods for discovering molecules which are useful in detecting and/or modulating the activation and/or conjugation of NEDD8. The present invention arises from the purification and characterization of novel NEDD8 activating and conjugating enzymes.
US08329407B2 Method for conducting reactions involving biological molecules in plugs in a microfluidic system
The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.
US08329406B2 Method of separating and distinguishing walnut from pecan nut
Provided is a method whereby walnut can be simply, rapidly and accurately separated and distinguished from pecan nut. The method involves a PCR method for specifically detecting nuts of the family Juglandaceae and identifying the matK sequence of pecan nut to thereby discriminate walnut and pecan nut from each other optionally using restriction enzymes.
US08329405B2 Method for detection of mutant alleles combining real time PCR and REMS-PCR
The invention provides an amplification system for the simultaneous detection of mutant alleles, and identification of the specific mutated sequence. A sample is enriched and simultaneously genotyped by the presence of peptide nucleic acids (PNAs) probes in an homogeneous single tube amplification reaction, by detecting the cleavage of a fluorophore quencher from the 5′-end of PCR products and, concurrently, selecting DNA that includes specific mutations relative to wild type, by employing a thermostable endonuclease that will only cleave an amplicon formed on a mutation bearing template strand. Oligonucleotides and kits for conducting the amplification system are also provided.
US08329404B2 Reagents, methods, and libraries for bead-based sequencing
The present invention provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single stranded template. The cycles comprise steps of extension, ligation, and, preferably, cleavage. In certain embodiments the methods make use of extension probes containing phosphorothiolate linkages and employ agents appropriate to cleave such linkages. The invention provides methods of determining information about a sequence using at least two distinguishably labeled probe families. In certain embodiments the methods acquire less than 2 bits of information from each of a plurality of nucleotides in the template in each cycle. In certain embodiments the sequencing reactions are performed on templates attached to immobilized beads. The invention further provides sets of labeled extension probes containing phosphorothiolate linkages. In addition, the invention includes performing multiple sequencing reactions on a single template by removing initializing oligonucleotides and extended strands and performing subsequent reactions using different initializing oligonucleotides.
US08329400B2 Methods for nucleic acid mapping and identification of fine-structural-variations in nucleic acids
A method of juxtaposing sequence tags (GVTs) that are unique positional markers along the length of a population of target nucleic acid molecules is provided, the method comprising: fragmenting the target nucleic acid molecule to form target DNA insert; ligating the target DNA insert to a DNA vector or backbone to create a circular molecule; digesting the target DNA insert endonuclease to cleave the target DNA insert at a distance from each end of the target DNA insert yielding two GVTs comprising terminal sequences of the target DNA insert attached to an undigested linear backbone; recircularizing the linear backbone with the attached GVTs to obtain a circular DNA containing a GVT-pair having two juxtaposed GVTs; and recovering the GVT-pair DNA by nucleic acid amplification or digestion with endonuclease having sites flanking the GVT-pair. Cosmid vectors are provided for creating GVT-pairs of ˜45- to 50-kb separation sequencable by next-generation DNA sequencers.
US08329397B2 Chemiluminescence proximity nucleic acid assay
This invention relates to the detection and quantitation of target nucleic acids in a heterogeneous mixture in a Sample and the methods of use thereof. The detection system includes a chemiluminescent molecule, a chemiluminescent substrate, a dye that is light responsive when intercalated into nucleic acids and nucleic acids. This invention is useful in any application where detection of a specific nucleic acid sequence is desirable, or where the detection of enzymes that modify nucleic acids is desirable such as diagnostics, research uses and industrial applications.
US08329393B2 Method for detecting and removing endotoxin
The present invention relates to bacteriophage tail proteins and the derivatives and fragments thereof that are capable of binding endotoxins in the absence of bivalent positive ions, especially Ca2+ or Mg2+. Further, the present invention relates to methods for depleting endotoxins from solutions and samples using the bacteriophage tail proteins according to the present invention and to a detection method for endotoxins.
US08329390B2 Detection of transmembrane potentials using N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonols
The present invention relates generally to the detection and measurement of transmembrane potentials using an N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonol (shown below). In particular, the present invention is directed to compositions and optical methods for determining transmembrane potentials across the plasma membrane of biological cells using a slightly hydrophobic N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonols. The method comprises a slightly hydrophobic N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonol anion capable of redistributing from a first face of the membrane to a second face of the membrane in response to changes in the potential of the membrane. In one aspect the method is used to identify compounds which modulate membrane potentials in biological membranes. wherein R1, R2, and R3 are independently selected from the group consisting of hydrogen, alkyl, haloalkyl and heteroalkyl; n is an integer from 1 to 3; Z is Na, K, ammonium or other biologically acceptable salt.
US08329372B2 Liquid developer, method of preparing liquid developer, and image forming apparatus
An liquid developer includes insulating liquid and toner particles dispersed in the insulating liquid. An average particle diameter of the toner particles based on volume is in the range of 0.7 to 3 μm, a width S of particle size distribution of the toner particles represented by the following formula (I) is 1.4 or less, and the insulating liquid include the unsaturated fatty acid glyceride: S=[D(90)−D(10)]/D(50)  (I), where D(X) represents the particle diameter at the point of X % in which X is the ratio of accumulated volume to the total volume when the volume is accumulated from the small particle diameter in the particle size distribution of the toner particles.
US08329359B2 Polymer electrolyte fuel cell
For a combination of a solid polymer electrolyte membrane 107, catalytic layers 111 and 113 disposed on both sides of the solid polymer electrolyte membrane 107, gas diffusion layers 112 and 114 disposed outside the catalytic layers 111 and 113, and separators 103 and 104 disposed outside the gas diffusion layers 112 and 114, the catalytic layer 113 to be cathode-sided includes a carbon carrier 117 composed of carbon having a mean lattice plane spacing d002 of [002] planes calculated from an X-ray diffraction within a range of 0.343 nm to 0.358 nm, a crystallite size Lc within a range of 3 nm to 10 nm, and a specific surface area within a range of 200 m2/g to 300 m2/g, catalyst particles 115 containing platinum supported on the carbon carrier 117, and an electrolyte 116. According to the invention, a polymer electrolyte fuel cell is allowed to prevent a corroding deterioration of carbon carriers in the cathode catalytic layer in start and stop of the fuel cell, allowing for an enhanced stable output over a long term.
US08329355B2 Fuel cell separator and gas diffusion layer
In a fuel cell, an elastic body provides first protrusion T10 that encompasses the perimeter of the passage hole at plate member 40 and the leading edge of which spans the entire region and tightly adheres to plate member 40, provides second protrusion S20 that is disposed within the placement region of reaction membrane 10 so as to encompass the perimeter of the gas diffusion layer, and provides third protrusion S30 that is disposed to encompass the region at which first protrusion T10 is disposed and the region at which second protrusion S20 is disposed, and is disposed outside the placement region for the reaction membrane, and the leading edge of which spans the entire region and tightly adheres to a separator 30.
US08329352B2 Fuel cell system using heat exchanging element
A heat exchanging element adapted to a fuel cell system includes a plurality of heat exchanging units and a fixing unit. The heat exchanging units are arranged to be spaced apart from one another along a first direction. The fixing unit fixes the heat exchanging units. Each of the heat exchanging units is demarcated into a first part and a second part extending from the first part by the fixing unit. A thermal conductivity coefficient of each of the heat exchanging units is higher than that of the fixing unit. The fixing unit is configured to slow heat conduction between the heat exchanging units. The heat exchanging element improves a heat recovery efficiency of the fuel cell system. In addition, two kinds of fuel cell systems using the above-mentioned heat exchanging element are provided.
US08329342B2 Anode material for lithium secondary batteries and lithium secondary batteries
The present invention is to provide a lithium ion secondary battery that realizes to raise an initial charge and discharge efficiency without deteriorating its charge and discharge characteristic in comparison with the conventional technology.A carbon material and a lithium ion secondary battery using the carbon material as the anode material, wherein the face interval d002 of the carbon material determined by an X ray diffraction apparatus is not less than 0.340 nm and not more than 0.370 nm, and further, V1/V2 representing a ratio of a volume V1 of pores having diameters from not less than 1 nm to less than 10 nm in the carbon material with respect to a volume V2 of pores having diameters from not less than 10 nm to less than 100 nm therein is not more than 0.2.
US08329340B2 Negative electrode, and non-aqueous electrolyte secondary battery using the same
A negative electrode for a non-aqueous electrolyte secondary battery is provided. The negative electrode includes: an electro-conductive base; a first layer provided on the electro-conductive base; and a second layer provided on the first layer. The first layer includes at least a graphitic material as a negative active material. The second layer includes at least a non-graphitizable carbonaceous material as a negative active material.
US08329335B2 Sealed-type secondary battery with integrated battery container formed with a polypropylene-based resin
A sealed-type secondary battery is disclosed. A battery module of a sealed-type secondary battery is formed by heating and fusing a top lid member and an integrated battery container. The integrated battery container is formed with a polymer alloy including a polyphenylene ether resin and a polyolefin resin, and the top lid member or a lateral lid member is formed with a polypropylene-based resin. A nucleating agent is added to the polypropylene-based resin of the top lid member or the lateral lid member, to improve mechanical strength, and the molecular weight is increased to reduce a melt flow rate MFR to approximately the same degree as the polymer alloy.
US08329334B2 Lithium secondary battery
A lithium secondary battery that is excellent in resistance to short-circuits and heat, is unlikely to suffer a capacity loss due to impact such as dropping, and has a high capacity. The lithium secondary battery includes an electrode assembly including a strip-like positive electrode and a strip-like negative electrode that are wound together with a porous heat-resistant layer interposed therebetween, a non-aqueous electrolyte, and a battery can. The battery has a restricting part for restricting vertical movement of the electrode assembly. The distance A from the restricting part to the inner bottom face of the battery can and the width B of the negative electrode satisfy the relation: 0.965≦B/A≦0.995.
US08329333B2 Battery module with plurality of batteries having bent terminal portions connected with fixing plate
A battery module includes a plurality of unit batteries, each including a positive terminal and a negative terminal which protrude outside of each unit battery and which have bent terminal portions, and a connection member which electrically connects the unit batteries with each other and which includes a fixing plate fixed to the bent terminal portions of adjacent unit batteries by welding so as to improve productivity and provide high stability.
US08329332B2 Electrochemical storage cell retention system
An electrochemical storage cell retention system is provided for storage cells (1) with a container comprising a bottom portion (12), and a top portion (11) provided with electrical output terminals (13, 14). The system comprises a first tray member (2) provided with through openings (20) and a plurality of adapter cups (3), each adapter cup (3) being designed to be placed on the top portion (11) of a storage cell (1) and to be received in one of the through openings (20) of the first tray member. The retention system is modular and mechanically strong.
US08329329B2 Battery cover and electronic device using the same
A battery cover includes a main body, two guiding members, a resilient member received in the main body, and an end cover arranged at one end of the main body. The guiding members are slidably received in the main body. The resilient member resists the guiding members. The resilient member not only provides an elastic force, but also positions the at least one guiding member in the main body.
US08329325B2 Battery cooling with mist evaporation and condensation
A battery pack cooling system may utilize a shroud defining a throat and a body, which may contain a battery pack. An evaporator may be arranged against the battery pack. A liquid coolant delivery pipe may deliver liquid coolant from a reservoir to the throat section with the aid of gravity, a pump, or an ultrasonic misting device. A spray nozzle may also deliver liquid coolant into the throat. When in the throat, liquid coolant mixes with air blown by a fan. Gaps in the battery pack may align with gaps of the evaporator to permit liquid and air to be blown completely through the battery pack and through the evaporator. A refrigeration system including a refrigerant compressor, a condenser and an expansion device work to cool the evaporator to condense, cool and remove liquid coolant from the liquid and air mixture, and deposit it in the reservoir.
US08329323B2 Battery pack heat transfer
A battery pack for thermal conduction of heat from a battery cell to a portable computer system is described. The battery pack comprises a housing, a battery cell within the housing, at least one electrode, and a thermal transfer contact separate from the at least one electrode. The thermal transfer extends through the housing and transfers heat from the battery cell to external of the battery pack.
US08329320B2 Laminated high moment film for head applications
A laminated high moment film with a non-AFC configuration is disclosed that can serve as a seed layer for a main pole layer or as the main pole layer itself in a PMR writer. The laminated film includes a plurality of (B/M) stacks where B is an alignment layer and M is a high moment layer. Adjacent (B/M) stacks are separated by an amorphous layer that breaks the magnetic coupling between adjacent high moment layers and reduces remanence in a hard axis direction while maintaining a high magnetic moment and achieving low values for Hch, Hce, and Hk. The amorphous material layer may be made of an oxide, nitride, or oxynitride of one or more of Hf, Zr, Ta, Al, Mg, Zn, Ti, Cr, Nb, or Si, or may be Hf, Zr, Ta, Nb, CoFeB, CoB, FeB, or CoZrNb. Alignment layers are FCC soft ferromagnetic materials or non-magnetic FCC materials.
US08329317B2 White light emitting organic electroluminescence element, display and illuminator
A white light emitting organic electroluminescent element comprising two electrodes having therebetween one or more constituting layers including a light emission layer, the one or more constituting layers comprising at least two phosphorescent compounds, wherein at least one of the phosphorescent compounds is a green light emitting ortho metalated complex; and a spectral ratio of the green light emitting ortho metalated complex in ae emission spectral distribution in a range of 400-800 nm is not less than 60%.
US08329315B2 Ultra thin copper foil with very low profile copper foil as carrier and its manufacturing method
The present invention relates to an ultra thin copper foil with a very low profile copper foil as a carrier, comprising a carrier foil a release layer and an ultra thin copper foil. The copper foil with the Very Low Profile, smooth on both sides (i.e. VLP copper foil) is used as the carrier foil, the said very low profile copper foil for supporting the ultra thin copper foil can bring advantages of no pinhole, excellent thickness uniformity and low surface roughness. The impact of a release layer on the bond strength between the carrier foil and the ultra thin copper foil is very significant, the release layer is composed of a quaternary metal alloy with peelability. The inventive ultra thin copper foil with the very low profile copper foil carrier shows low carrier bonding strength, not only having exceptional environment endurance, still exhibiting high temperature, moisture, acid, alkali resistances and other characteristics, the carrier foil and the ultra thin copper foil has excellent stripping properties even at the high temperature hot-pressurized environment.
US08329309B2 Paper-based lidding for blister packaging
A paper-based lidding material includes a paper layer and a layer containing a cyclic olefin copolymer. The material is useful for blister packaging and particularly suitable for push-through pharmaceutical and food blister packaging. In one embodiment, the lidding material is formed by extrusion coating and includes at least one paper layer, at least one primer layer, at least one tie layer, at least one barrier layer containing one or more cyclic olefin copolymers, and at least one sealant layer in that order. In another embodiment, the paper-based lidding material includes a paper layer laminated to one or more barrier layers containing one or more cyclic olefin copolymers adjacent to one or more sealant layers. Embodiments of the invention can be sealed to a variety of blister films, including films that are chloride-free, to provide environmentally benign blister packages having good moisture properties.
US08329306B2 Barrier laminate, gas barrier film, and device using the same
Provided is a barrier laminate having higher barrier property. The barrier laminate has an organic layer obtained by curing a polymerizable composition comprising a compound represented by the following formula (1); wherein R1's represent a substituent, and R1's each may be the same or different to each other; n's are an integer of 0 to 5, and n's each may be the same or different to each other; provided that at least one of R1's comprises a polymerizable group.
US08329302B2 Glass or glass-ceramic articles with decorative coating
In order to provide a decorative coating (9) which exhibits improved temperature resistance and strength on glass and glass-ceramic and which also has no strength-reducing effect on the substrate (3), or at least no longer has any substantially strength-reducing effect on the substrate, the invention envisions a process for producing glass or glass-ceramic articles having a decorative layer in which at least one decorative pigment (13) is mixed with a sol-gel binder (11), and the pigment mixed with the sol-gel binder is cured on the glass or glass-ceramic substrate of the article by annealing, to form a decorative layer having a porous ceramiclike structure.
US08329301B2 Fluoroelastomer containing intermediate transfer members
An intermediate transfer member that includes a core shell component wherein the core is, for example, comprised of a metal oxide, and the shell is comprised of a silica, which shell contains or includes a hydrophobic agent, and where the core shell is dispersed in or mixed with a fluoroelastomer.
US08329299B2 Sol-gel coating methods and thin film coated substrates therefrom
A method for depositing sol-gel derived coatings on substrates to form coated substrates includes the steps of providing a first solution including at least one sol precursor and at least one solvent. A water comprising solution is added to the first solution to form a sol-gel. The sol-gel is deposited on a substrate. The sol-gel layer on the substrate is dried/cured at a temperature ≦100° C. for at least 10 minutes to form a solid layer, wherein the solid layer has a thickness from 50 nm to 110 nm. The depositing and curing steps are repeated at least once until combined thickness of the solid layers forms a coating of a predetermined thickness. The resulting solid layers are low water content layers that can be evidenced by transmission measurements. The coated substrate can be an IR transmissive substrate having a recrystallization temperature <130° C. and each of the solid layers provide a transmission at λ=2950 nm, normal incidence and 1 mW power if placed on the IR transmissive substrate of ≧99% of the transmission directly through the IR transmissive substrate.
US08329293B2 Carbon fiber composite material
A carbon fiber composite material having an elastomer and vapor-grown carbon fibers dispersed in the elastomer. The vapor-grown carbon fibers are rigid fibers having an average diameter of 20 to 200 nm, an average length of 5 to 20 micrometers, and an average value of bending indices defined by the following expression (1) of 5 to 15, Bending index=Lx÷D  (1) Lx: length of linear portion of the vapor-grown carbon fiber, and D: diameter of the vapor-grown carbon fiber. The carbon fiber composite material has a dynamic modulus of elasticity (E′) at 150° C. of 30 MPa or more and an elongation at break (EB) of 140% or more.
US08329291B2 Multi-layered composite system and method
A multi-layered composite includes a polymer adhesive layer and a polymer support film layer that becomes intimately incorporated with the polymer adhesive layer upon application of heat.
US08329290B2 Silicone resin composition
A silicone resin composition containing (i) a silicone resin and (ii) fine metal oxide particles without having a reactive functional group or with a protected reactive functional group on the surface thereof (fine metal oxide particles B), wherein the silicone resin is obtained by carrying out a polymerization reaction between a silicone derivative having an alkoxysilyl group at an end of a molecule and a molecular weight of from 200 to 3000, and fine metal oxide particles having a reactive functional group on the surface thereof (fine metal oxide particles A), and wherein the fine metal oxide particles B are dispersed in the silicone resin (Embodiment 1); a silicone resin.
US08329289B2 Composites of inorganic and/or organic microparticles and nano-calcium carbonate particles
The present invention relates to composites, comprising inorganic and/or organic pigments and/or fillers in the form of microparticles, the surface of which is coated at least partially with finely divided nano-calcium carbonate with the help of binders based on copolymers comprising as monomers one or more dicarboxylic acids and one or more monomers from the group of diamines, triamines, dialkanolamines or trialkanolamines, a method for producing such composites, aqueous slurries thereof and their use in papermaking or in the field of paint and plastic production and the use of the inventive binders for coating the microparticles with nano-calcium carbonate.
US08329287B2 Void-containing resin molded product, production method therefor, and reflective plate
A void-containing resin molded product consisting of a polymer having crystallinity, wherein the void-containing resin molded product has elongated voids whose longitudinal directions are aligned in one direction, wherein the elongated voids satisfy the expression h(avg)>T/100, where h(avg) denotes an arithmetic average of h(i)s which each denote a distance from a surface of the void-containing resin molded product to a center of each of 10 voids whose centers are closer to the surface of the void-containing resin molded product than are centers of any other voids in a cross-section of the void-containing resin molded product that is perpendicular to a direction in which the voids are aligned, the 10 voids being selected from voids in a region defined by one straight line which is parallel to a thickness direction of the void-containing resin molded product and another straight line which is parallel to and distant by 20×T from the one straight line; and T denotes an arithmetic average thickness of the cross-section, and wherein the elongated voids have a ratio L/r of 10 or more, where L denotes an average length of the voids (in μm) in a direction in which the voids are aligned, and r denotes an average length of the voids (in μm) in a thickness direction which is perpendicular to the direction in which the voids are aligned.
US08329281B2 Load bearing fabric assembly and method of making a load bearing fabric assembly
A load bearing fabric assembly having a frame, a carrier and a load bearing fabric. The load bearing fabric is attached directly to the carrier. The frame defines view ports to enable visual inspection of the junction between the carrier and the load bearing fabric after the carrier and fabric have been mounted to the frame. A method of manufacturing the carrier for such a load bearing fabric assembly includes the steps of: (a) placing the fabric inside a mold with at least a portion of the fabric directly engaging the surface of the mold; (b) injecting a molten thermoplastic into the mold to form the carrier, the molten thermoplastic having a melt point greater than that of the fabric; and (c) permitting the molten thermoplastic to cure to form a carrier directly on the fabric. In one embodiment, the fabric is positioned so that the entry of molten thermoplastic urges the fabric against a surface of the mold cavity.
US08329280B2 Chopped fiber bundle, molding material, and fiber reinforced plastic, and process for producing them
A chopped fiber bundle includes a large number of unidirectionally arranged reinforced fibers. The length of each of the reinforced fibers is in the range of 5 to 100 mm. The chopped fiber bundle has a transition segment in which the number of the reinforced fibers increases toward the central part of the chopped fiber bundle in the aligned direction of the reinforced fibers with both ends in the aligned of the reinforced fibers in the chopped fiber bundle being a starting point. The level of a change in total sectional area of the large number of reinforced fibers is not more than 0.05 mm2 per mm in the aligned direction of the reinforced fibers over the whole area in the longitudinal direction of the chopped fiber bundle.
US08329279B2 Electrooptic apparatus
An electrooptic apparatus includes an electrooptic material interposed between a pair of substrates, and a film formed above each of surfaces of the substrates facing the electrooptic material. The film is formed by a method including (a) forming a frame-shaped partition in an application area on the substrate, the partition having a side surface facing a center of the application area, (b) applying the material liquid to the application area, and (c) drying the material liquid. In step (a), the partition is formed so that a distance between the side surface of the partition and the center is smaller than a distance between an outer edge of the application area and the center, and so that a height of the partition is smaller than a film thickness of the material liquid at a time when the material liquid is applied and is larger than a thickness of the dried film.
US08329267B2 Flexible edge seal for vacuum insulating glazing units
A flexible edge seal is provided for a vacuum insulating glazing unit having a first glass pane and a second glass pane spaced-apart from the first. The edge seal comprises a seal member formed of a hermetically bondable material and having a first end, a second end and a center section disposed therebetween. The first end is hermetically bondable to a first glass pane. The second end is hermetically bondable to a second glass pane. The center section comprises a plurality of convolutes.
US08329262B2 Dielectric film formation using inert gas excitation
Methods of forming a silicon-and-nitrogen-containing layers and silicon oxide layers are described. The methods include the steps of mixing a carbon-free silicon-containing precursor with plasma effluents, and depositing a silicon-and-nitrogen-containing layer on a substrate. The silicon-and-nitrogen-containing layers may be made flowable or conformal by selection of the flow rate of excited effluents from a remote plasma region into the substrate processing region. The plasma effluents are formed in a plasma by flowing inert gas(es) into the plasma. The silicon-and-nitrogen-containing layer may be converted to a silicon-and-oxygen-containing layer by curing and annealing the film.
US08329261B2 Marine antifoulant coating
A protective coating applied to the underwater portion of a marine vessel operable to inhibit the growth of marine foulants. The coating comprises a polymer, a marine biocide, a preservative, and optionally an antimicrobial agent. In certain embodiments, the marine biocide, preservative, and optional antimicrobial agent are chemically bonded with the polymer thereby significantly reducing the ability of the biocide, preservative, and antimicrobial agent to leach from the coating into the surrounding environment.
US08329260B2 Cooled cleaving implant
A substrate is implanted with a species to form a layer of microbubbles in the substrate. The species may be hydrogen or helium in some embodiments. The size at which the microbubbles are stable within the substrate is controlled. In one example, this is by cooling the substrate. In one embodiment, the substrate is cooled to approximately between −150° C. and 30° C. This cooling also may reduce diffusion of the species in the substrate and will reduce surface roughness when the substrate is cleaved along the layer of microbubbles.
US08329258B2 Method and device for electrostatic coating of an electrically conducting workpiece with coating powder
The method according to the invention for electrostatic coating of an electrically conducting workpiece with coating powder includes the following steps. The workpiece is earthed. Then an electrode has a negatives potential applied to it compared to that of the workpiece and a counter-electrode has a positive potential applied to it compared to that of the workpiece. The potential in the area of the workpiece in which the workpiece is to be coated is set to zero, by means of a control unit. Afterwards the workpiece is sprayed with coating powder in the area to be coated using a powder spray gun.
US08329256B2 Method and device for the production of moulded pieces from a layer of polyurethane
The invention relates to a process and a device for the production of mouldings containing a layer of polyurethane in shot operation, in which a gas stream is introduced into the flow channel of the spray device in at least two positions.
US08329249B2 Magnetic recording medium, magnetic recording and reproducing device with magnetic recording medium, and magnetic-recording-medium manufacturing method
Although dots and servo patterns are made of the same magnetic material, the dots have a relatively low coercive force so as to allow data deletion and rewrite by a magnetic head, while the servo patterns have a high coercive force compared with the coercive force of the dots. The coercive force of the servo patterns is strong enough so as to eliminate the influence of shape magnetic anisotropy.
US08329247B2 Methods for producing omni-directional multi-layer photonic structures
A method for producing a multi-layer photonic structure having at least one group of alternating layers of high index material and low index material may include, determining a characteristic property function for the multi-layer photonic structure, determining a thickness multiplier for the at least one group of alternating layers based on a comparison of the characteristic property function to a target profile, adjusting the characteristic property function with the determined thickness multiplier, and comparing an adjusted characteristic property function to the target profile, wherein, when the adjusted characteristic property function does not approximate the target profile, at least one additional group of layers is added to the multi-layer photonic structure.
US08329246B2 Oriented collagen gel
Techniques for the production of flow-oriented collagen gels using hydrodynamics to influence the assembly of collagen fibers. Highly concentrated monomeric solutions of collagen are subjected to shear and extensional flow as they are drawn onto a substrate to induce fibrillogenesis under a high Ph buffer. The produced gel captures the flow induced ordering of molecular collagen upon fibril formation. The depositing or the induction of fibrillogenosis occurs without the application of a magnetic field to the concentration of collagen. These highly oriented 3D scaffolds are capable inducing contact guidance and guiding mammalian cell growth. The collagen fibers mimic the construction of in vivo fibers with the characteristic D-periodicity and the integrin receptors on the fibroblasts respond to this organization. The industrial applications of three-dimensional collagen gels as a biomaterial are widespread from drug delivery to burn repair or tissue engineering system.
US08329244B2 Friable, baked potato pieces and process
Potatoes are processed to develop baked and fried flavors and aromas. The are baked to create a number of characteristic baked flavors and textures. When fried, a whole other group of flavors and textures is achieved. To avoid damage to the discrete potato pieces that are prepared in processing and are desired in the final product, the process entails baking potatoes; pressing the potatoes to a predetermined thickness; freezing the potatoes; breaking the potatoes into discrete pieces; drying the discrete pieces to form a skin thereon and preferably lightly brown the surfaces; and freezing and packaging the pieces. Oven heating will be sufficient to provide a browning effect to a light golden to golden brown color and form a skin on the exterior surface of exposed potato pulp, both important to the preparation of the best product.
US08329242B2 Process for making chocolate
A process for producing a chocolate or chocolate-like product comprises: (i) mixing a part of the components of the chocolate or chocolate-like product to form a mixture; (ii) homogenizing the mixture with fat using a rotor/stator homogenizer; and (iii) conching the homogenized mixture.
US08329240B2 Milk powder
A method of improving the flow properties or cold solubility of a milk powder and use of the modified powder in beverage distribution machine for delivering, in particular, cold beverages. The method includes controlling glycation of proteins in the range of 10 to 35% blocked lysine and lactose crystallization between 5 and 50%. The resulting powder also represents an embodiment of the invention.
US08329239B2 Off-taste masking
A method of masking the off-taste of an artificial or natural sweetener, comprising the addition to the sweetener of at least one compound according to the formula I in which R1 is selected from H, C1-C4 alkyl and Ph: R2 is selected from H and Me: R3 is selected from H, C1-C4 alkyl and Ph: R4 is selected from H and C1-C4 alkyl: or R3, R4 together form a five, six or seven-membered aliphatic ring.
US08329238B2 Cooling composition
Novel cooling compositions having a natural status are object of the present invention. These compositions comprise a combination of menthol, together with a nature identical ingredient and at least one natural extract. They can be added to flavoring compositions to impart cooling sensations devoid of mentholic flavoring notes.
US08329236B2 Low sodium salt composition
The present invention relates to a low sodium salt composition and the methods used to make it. The low sodium salt composition includes sodium chloride and a modified chloride salt composition. The modified chloride salt composition includes a homogenous amalgamation of chloride salt, food grade acidulant, and carrier, which does not contain sodium chloride. The low sodium salt composition is made using a two step. The first step includes making a modified chloride salt composition and the second step includes combining the modified chloride salt composition with sodium chloride to form a low sodium salt composition.
US08329235B2 Method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum products
The invention relates to a method for producing chewing gum granules. The method comprises at least the steps of feeding a gum composition including at least gum base into an extruder (2), pressurizing the gum composition in the extruder, extruding the gum composition through a die plate (5), and cutting the extruded gum composition in a liquid filled chamber (4). Flavor is added to the composition in the extruder prior to the granulation into cooling liquid. The temperature and pressure of the flavored gum composition is controlled so that the temperature is below 70° C. when the pressure is in the range from 1 to 5 hPa.
US08329231B2 Method of preventing photo-aging with ashwagandha and Indian gooseberry
A method of preventing photo-aging and its related causes includes administering a therapeutic composition comprising extracts of the plant species ashwagandha (Withania somnifera) and Indian gooseberry (Phyllanthus emblica). A composition of ashwagandha and Indian gooseberry may: (1) lower cortisol and increase DHEA, (2) prevent free radical-induced photoaging, (3) inhibit collagenase activity in vitro, (4) inhibit hyaluronidase activity in vitro, (5) display superior cascading antioxidant activity, (6) reduce C-reactive protein, and (7) enhance mood.
US08329224B2 Ion exchange resin treated to control swelling
The present invention provides a method and composition for loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle. The drug-loaded resin particle is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-loaded resin particle from the solution.
US08329220B2 Controlled release formulations
The present invention provides stable, self-assembling, biocompatible and biodegradable hydrogel formulations, into which one or more compounds may be incorporated allowing for delayed release or controlled release of the incorporated compounds as the hydrogel is degraded in the body.
US08329219B2 Methods for producing ECM-based biomaterials
A method for forming an extracellular matrix material (ECM) material includes providing at least an ECM composition containing ECM particles varying in their capacity for migration through a fluid medium, including at least one population of expanded ECM particles. The ECM composition is combined in a fluid medium to form a flowable ECM composition. The flowable ECM composition is subjected to a centrifugal force in a mold for a period of time sufficient to distribute the ECM particles according to differences in their physical characteristics. The ECM composition is dried to form a dried ECM material having a density gradient extending from a less dense region to a more dense region. The dried ECM material may formed as a porous, substantially acellular ECM material expandable in an aqueous fluid environment by at least 100% in volume.
US08329215B2 Shell and core dosage form approaching zero-order drug release
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.
US08329212B2 Abuse potential reduction in abusable substance dosage form
The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
US08329207B2 Compositions and methods for the sustained release of beta-alanine
Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein.
US08329202B2 System and method for attaching soft tissue to an implant
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein said porous region exhibits a nano-textured surface, and a biocompatible polymer matrix coating the nano-textured surface. The polymer matrix coating comprises a naturally occurring extracellular matrix with biocompatible inorganic materials distributed within the matrix, or a biocompatible polymer and an osteo-inductive agent.
US08329200B2 Cosmetic or dermatological stick
The present invention is a water-in-oil emulsion having a high content of water and relatively high amounts of skin-moisturizing agents and a cosmetic or dermatological stick including the water-in-oil emulsion. The present invention also includes methods of moisturizing the skin using the water-in-oil emulsion. The water-in-oil emulsion is solid at room temperature and comprises a fatty phase with at least one oil component and at least one wax component, an aqueous phase with a skin-moisturizing agent in addition to water, a water-in-oil emulsifier having the general structure A-B-A′, where A′ and A′ represent the same or different hydrophobic inorganic groups and B is a hydrophilic group.
US08329197B2 Ex vivo uses of immunostimulatory combinations
The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
US08329195B2 Detoxified pneumococcal neuraminidase and uses thereof
Provided herein are compositions designed to reduce or prevent pneuomococcal infections, nasal carriage, nasal colonization, and central nervous system invasion. Provided herein is a composition comprising a polypeptide comprising the amino acid sequence of SEQ ID NO: 19 or a variant thereof that can elicit an anti-neuraminidase immune response. Further provided are methods of making and using the compositions disclosed herein. Specifically provided are methods of generating antibodies in a subject comprising administering to the subject an agent or composition taught herein. Also provided are methods of reducing or preventing nasal carriage or pneumococcal infection in a subject comprising administering to the subject a composition taught herein.
US08329192B2 Campylobacter polypeptides and methods of use
The present invention provides isolated metal regulated polypeptides obtainable from a Campylobacter spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for treating in infection in a subject, for treating a condition caused by a Campylobacter spp., and for decreasing colonization of an animal.
US08329190B2 Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonization, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
US08329186B2 Treatment of inflammation using BST2 inhibitor
The application discloses a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst2 antagonist.
US08329182B2 Immunoglobulin chimeric monomer-dimer hybrids
The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
US08329181B2 Methods for treating B-cell lymphoma by administering an anti-CD20 antibody
The present invention provides methods for treating a B-cell lymphoma in a human subject. The methods of the invention comprise administering to a subject in need thereof an antibody or antigen-binding fragment thereof that specifically binds human CD20. In certain embodiments, the methods of the invention are useful for treating non-Hodgkin's B-cell lymphoma.
US08329178B2 Antibodies against CXCR4 and methods of use thereof
The invention provides human monoclonal antibodies or fragments thereof, that specifically bind to CXCR4. Disclosed are methods of use of such antibodies for the treatment and/or prevention of a CXCR4 disease or disorder such as cancer and X4-tropic HIV-1 infection Also provided are methods of use of such antibodies and antibody fragments for the treatment or prevention of cancer metastasis. The invention provides methods of mobilizing CD34+stem cells from the bone marrow and methods of blocking chemotaxis of CXCR4-expressing cells in response to SDF-1. Also provided are methods of use of the antibodies and fragments thereof for the prevention or treatment of graft-versus-host disease. Finally, the invention provides methods of inhibiting new tumor blood vessel formation and/or tumor cell angiogenesis.
US08329176B2 Method for inhibiting bone resorption
The invention is directed to a method of inhibiting bone resorption. The method comprises administering to a human an amount of sclerostin inhibitor that reduces a bone resorption marker level for at least 2 weeks. The invention also provides a method of monitoring anti-sclerostin therapy comprising measuring one or more bone resorption marker levels, administering a sclerostin binding agent, then measuring the bone resorption marker levels. Also provided is a method of increasing bone mineral density; a method of ameliorating the effects of an osteoclast-related disorder; a method of treating a bone-related disorder by maintaining bone density; and a method of treating a bone-related disorder in a human suffering from or at risk of hypocalcemia or hypercalcemia, a human in which treatment with a parathyroid hormone or analog thereof is contraindicated, or a human in which treatment with a bisphosphonate is contraindicated.
US08329175B2 Methods and compositions for the treatment and diagnosis of endothelial cell disorders and angiogenic disorders
The invention features methods and compositions for treating and preventing angiogenic disorders and endothelial cells disorders using HspA12B antagonist and HspA12B agonist compounds, respectively.
US08329172B2 Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody
New combined therapeutic regimens for treatment of B-cell lymphomas are disclosed which comprise in particular administration of anti-CD20 antibodies to patients having low-, intermediate- or high-grade non-Hodgkins lymphomas.
US08329170B2 Method for treating psoriasis by administering an anti-IL-12 antibody
An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in treating IL-12-related disorders, such as psoriasis.
US08329167B2 EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart diseases
The present invention refers to human EGLN2 variants having at position 58 of the amino acid sequence a serine or a leucine and their use in the prevention or treatment of thromboembolic or coronary heart diseases, in particular stroke, prolonged reversible ischemic neurological deficit (PRIND), transitoric ischemic attack (TIA), myocardial infarction and/or early myocardial infarction.
US08329164B2 Methods and compositions concerning poxviruses and cancer
The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.
US08329149B2 Topical lightening composition and uses thereof
The disclosure relates to novel topical lightening compositions a skin depigmenting agent and a vehicle. There is provided a topical lightening composition comprising a substituted-4-oxobutanoic acid, ester, or amide tyrosinase inhibitor, and a vehicle. The depigmenting agents of this disclosure can be used as such or as a pharmaceutically acceptable salt including conventional non-toxic salts which include a metal salt or an alkaline earth metal salt, an ammonium salt, or an organic base salt. The depigmenting agents of this disclosure can be incorporated into any cosmetically-, dermatologically-, or cosmeticatically-acceptable vehicle or carrier normally used for topical application. The compositions and methods of the disclosure are effective to lighten skin, hair, lips, and/or nails.
US08329147B2 Alkyl benzoate mixtures
The invention relates to alkyl benzoate mixtures, the sum of the C12- and C14-alkyl benzoates being greater than or equal to 85%, in relation to the total sum of the alkyl benzoates. The invention also relates to the use of said alkyl benzoate mixtures in cosmetic and/or pharmaceutical preparations, in particular as oil components.
US08329146B2 Hair treatment composition comprising a pressure sensitive adhesive
A hair treatment composition comprising an acrylic pressure sensitive adhesive.
US08329145B1 Use of cooling agent to improve cosmetics
A pumpable liquid spray formulation for retarding degradation of color cosmetics.
US08329143B2 Method and apparatus for kidney function analysis
A method and apparatus for determining physiological data related to an animal, such as kidney diagnostics data, is provided. The method includes injecting a mixture of a first and a second molecule into an animal (e.g., a human patient), determining a molecular ratio of the molecules, and determining the physiological data based on the molecular ratio. The apparatus includes a number of finger receiving apertures, a light generation circuit, a light detection circuit, a pulse counting circuit, and a user interface.
US08329142B2 Compounds, compositions and methods for medical imaging of Parkinson's disease
Compounds, compositions and methods for the detection and diagnosis of Parkinson's disease. Derivative lycerophosphocholine (GPC) compounds are used as a detection and diagnostic aid to measure progression of Parkinson's disease by detecting GPC binding to α-synuclein. Derivative CPG compounds including non-radioactive, paramagnetic, and radioactive derivatives of GPC are presented. These compounds possess similar binding properties to original GPC molecules and are useful in medical magnetic resonance imaging (MRI) and/or positron emission tomography (PET) applications. By employing these radiological techniques in conjunction with the compositions of the present invention, the detection, diagnosis and assessment of the progression of Parkinson's disease may be achieved.
US08329141B2 Locoregional internal radionuclide ablation of abnormal tissues
The present disclosure provides methods of using unsealed and non-colloidal radiopharmaceuticals, for example beta emitting radiopharmaceuticals such as Yttrium-90 chloride, Indium-111 chloride, F-18-2-deoxy-2-fluoro-D-glucose, or combinations thereof, for locoregional ablation of cells in the abnormal tissue.
US08329140B2 Method and system for hydrogen evolution and storage
A method and system for storing and evolving hydrogen (H2) employ chemical compounds that can be hydrogenated to store hydrogen and dehydrogenated to evolve hydrogen. A catalyst lowers the energy required for storing and evolving hydrogen. The method and system can provide hydrogen for devices that consume hydrogen as fuel.
US08329139B2 Process for the preparation of titanium dioxide with nanometric dimensions and controlled shape
The present invention relates to an industrial applicable process for the preparation of materials with nanometric dimensions and controlled shape, based on titanium dioxide. The invention also relates to a process for the preparation of titanium dioxide nanorods with anatase phase composition, which are highly suitable for applications involving photovoltaic cells, particularly Dye Sensitized Solar Cells (DSSC), photoelectrolysis cells and tandem cells for the conversion of solar energy and the production of hydrogen.
US08329138B2 Fullerene-like nanostructures, their use and process for their production
A nanostructure, being either an Inorganic Fullerene-like (IF) nanostructure or an Inorganic Nanotube (INT), having the formula A1−x-Bx-chalcogenide are described. A being a metal or transition metal or an alloy of metals and/or transition metals, B being a metal or transition metal B different from that of A and x being ≦0.3. A process for their manufacture and their use for modifying the electronic character of A-chalcogenide are described.
US08329136B2 Graphite particle, carbon-graphite composite particle and their production processes
The present invention relates to a graphite particle and a carbon-graphite composite particle both suitable for use in electrode for lithium ion secondary battery, as well as to processes for producing these particles. The graphite particle of the present invention has an average particle diameter of 5 to 50 μm, wherein one or more recesses having a depth of 0.1 to 10 μm are formed in the surface. The graphite particle is produced by a mixing step for mixing raw material graphite particles and recess-forming particles, a press molding step for press-molding the mixture composed of the raw material graphite particles and the recess-forming particles to obtain a molded article, a pulverization step for pulverizing the molded article, and a separation step for separating and removing the recess-forming particles from the pulverized molded article. The carbon-graphite composite particle of the present invention is produced by performing a thermal CVD step which comprises covering the surface of the above-mentioned graphite particle with a carbon layer.
US08329135B2 Aligned carbon nanotube bulk structure having portions different in density
An aligned carbon nanotube bulk structure in which various properties such as density and hardness are controlled depending on the place is provided.An aligned carbon nanotube bulk structure having different density portions is an aligned carbon nanotube bulk structure provided with a high-density portion applied with a density-increasing treatment and an low-density portion and having a plurality of carbon nanotubes (CNT) aligned in a predetermined direction, in which the structure has 1:3 or more of the degree of anisotropy in the alignment direction and in the direction vertical to the alignment direction and, in the (002) peak of the X-ray diffraction data in the high density region, the intensity of X-ray incident along the orientation direction is higher than that of the X-ray intensity from the direction vertical to the alignment direction, and the degree of alignment is defined by specific conditions.
US08329129B2 Method for preparing pyrochlore oxide, polymer electrolyte fuel cell, fuel cell system, and method for producing electro catalyst for fuel cell
The present invention provides a method for preparing a pyrochlore type oxide having a larger specific surface area, a polymer electrolyte fuel cell and a fuel cell system improved in power generation efficiency and capable of being produced more inexpensively, and a method for producing an electro catalyst for a fuel cell, which electro catalyst has a larger specific surface area, is relatively inexpensive, and has high electrode activity per unit mass. A method for preparing a pyrochlore type oxide represented by A2B2O7-Z wherein A and B represent a metal element, Z represents a number of 0 or more and 1 or less, A includes at least one selected from the group consisting of Pb, Sn, and Zn, and B includes at least one selected from the group consisting of Ru, W, Mo, Ir, Rh, Mn, Cr, and Re, wherein the pyrochlore type oxide is produced by a reaction of a halide or nitrate of A with an alkali salt of a metal acid of B. A method for producing an electro catalyst for a fuel cell, including producing this oxide in this manner. A polymer electrolyte fuel cell and a fuel cell system including this oxide.
US08329127B2 Combined slip catalyst and hydrocarbon exotherm catalyst
A catalyst comprising: (a) a first layer comprising an oxidizing catalyst having an effective PGM loading such that oxidation of hydrocarbons generates sufficient heat to regenerate soot, wherein said effective amount of PGM is greater than about 10 g/ft3; and (b) a second layer adjacent to said first layer and comprising a reducing catalyst to selectively reduce NOx.
US08329117B2 Microfluidic chip features for optical and thermal isolation
A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.
US08329116B2 Measuring chip
Provided is a measuring chip, which can spot a specimen liquid of a minute quantity for an immune agglutination easily and precisely to the measuring chip and which can prevent the flow of the specimen liquid and the contamination of the specimen. The measuring chip comprises at least two substrates, a spacer arranged between the substrates, at least one passage made of the substrates and the spacer into a hollow shape and having two open ends, counter electrodes for applying an electric field, and a specimen-spotted portion to be spotted with the specimen. The specimen-spotted portion has a structure made of a square, circular, elliptical or sector shape by that spacer. Moreover, the specimen-spotted portion has two open ends, one of which is connected to one open end of that passage.
US08329109B2 Segmented reactors for capacity and enrichment changes in conversion of uranium hexafluoride to uranium dioxide
A dry conversion reactor for converting uranium hexafluoride to uranium dioxide, the dry conversion reactor including a gas-phase reaction segment and a fluidized bed segment, wherein at least one of the gas-phase reaction segment and the fluidized bed segment is a replaceable segment. A method for operating a dry conversion reactor utilizing a uranium hexafluoride to uranium dioxide conversion process, the method including replacing at least one conversion reactor segment.
US08329108B2 Isoolefin-diolefin production process and apparatus therefore
In an isoolefin-diolefin rubber production process (e.g. a butyl rubber production process), the cold rubber slurry produced in the reaction vessel is transported from the reaction vessel to the flash tank during which time the cold slurry may be expressed to separate at least part of the cold liquid reaction medium from the isoolefin-diolefin rubber. The separated cold liquid reaction medium is transported off stream, for example by a mechanical filter, where it can be recycled back into the reaction vessel and/or where it can be used to cool a feed stream or streams of the reaction components. The isoolefin-diolefin rubber and the residual liquid reaction medium are transported to a flash tank for further processing. The ability to separate and recycle cold liquid reaction medium makes the process more economical. In one aspect, the slurry may be transported from the reaction vessel to the flash tank by a self-cleaning fully intermeshing co-rotating twin screw extruder, which helps overcome the problem of plugging due to rubber sticking to the surfaces of the slurry transfer apparatus.
US08329097B1 Sterilization of intraocular lenses
A packaged, sterilized intraocular lens prepared by a process comprising providing a hydrophobic acrylic, or low water acrylic, intraocular lens and positioning the acrylic lens in a lens enclosure with an aqueous solution to provide a lens package. The lens package is then heated to a temperature sufficient for sterilization, however, the heating of the lens package must begin before the acrylic lens reaches an equilibrated, hydrated state following contact of the lens with the aqueous solution. The resulting sterilized acrylic intraocular lens will have less than sixty percent of total volume of disc-like features, or less than forty percent of total volume of water vacuoles, after 60 days following sterilization compared to an acrylic lens of the same composition, which was sterilized under the same conditions, but in an equilibrated, hydrated state.
US08329096B2 Systems and methods for detecting descented material
Systems and methods for detecting presence of a thing, the thing treated with a descenter, one method including in an area in which it is possible that a thing treated with a descenter is present, using a detector to detect a descenter level in the area, producing a detected descenter level, comparing the detected descenter level to a normal descenter level for the area, determining that the detected descenter level is different from the normal descenter level, said determining indicating the possible presence of a thing treated with a descenter; and using a trained service animal to facilitate such a method.
US08329095B2 Preservative system for cosmetic formulations—compositions and methods thereof
The present invention relates to preservation of cosmetic formulations. More specifically, the present invention relates to a preservative composition for cosmetic formulations comprising thymol, monolaurin and magnolol obtained from supercritical fluid extracts of Magnolia officinalis.
US08329094B2 Magnesium alloy and process for producing the same
A magnesium alloy having excellent strength and elongation at high temperatures and further having excellent creep characteristics at high temperatures. Also provided is a process for producing the alloy. In producing the magnesium alloy, a magnesium alloy containing yttrium and samarium in respective specific amounts is cast and the resultant cast is subjected to a solution heat treatment, subsequently hot working, and then an aging treatment, thereby reducing the average crystal grain diameter of the structure. In addition, the amounts of the yttrium and samarium in solution in the magnesium matrix are balanced with the number of precipitate particles of a specific size in the crystal grains. The magnesium alloy thus obtained has excellent strength and elongation at high temperatures and further having excellent creep characteristics at high temperatures.
US08329093B2 Method for preparing metal-matrix composite and device for implementing said method
A method for preparing metal-matrix composites including cold-process isostatic compaction of previously mixed powders and hot-process uniaxial pressing of the resulting compact is disclosed. The method enables metal-matrix composites with improved properties to be obtained. A device for implementing isostatic compaction comprising a latex sheath into which the mixture of powders is poured, a perforated cylindrical container in which the latex sheath is arranged, and means for sealed insulation of the mixture of powders contained in the sheath is also disclosed.
US08329092B2 Metal powder for metal laser-sintering and metal laser-sintering process using the same
A metal powder for use in a metal laser-sintering wherein a three-dimensional shaped object is produced by irradiating a powder layer of the metal powder with a light beam to form a sintered layer and thereby laminating the sintered layers. The metal powder of the present invention is characterized in that it comprises an iron-based powder and at least one kind of powder selected from the group consisting of a nickel powder, a nickel-based alloy powder, a copper powder, a copper-based alloy powder and a graphite powder; and the iron-based powder has been annealed. In such metal powder, the iron-based powder is in a softened state due to the annealing treatment thereof. Accordingly, the use of the metal powder in a metal laser-sintering process makes it possible to reduce a machining resistance attributable to the residual metal powder adherent to the surface of the shaped object, which leads to an achievement of an extended lifetime of a machining tool.
US08329091B2 Porous metallic structures
In one aspect, there are provided methods for producing porous metallic structures, wherein the methods involve the use of collagen fibrils on the nanometer scale as a “sacrificial” scaffold upon which metal particles are deposited. Also disclosed are structures comprising a porous metallic matrix having favorable strength, porosity, and density characteristics. Structures produced in accordance with the present disclosure are useful for, inter alia, the fabrication of devices such as filters, heat exchangers, sound absorbers, electrochemical cathodes, fuel cells, catalyst supports, fluid treatment units, lightweight structures and biomaterials.
US08329086B2 Method of manufacturing liquid ejecting head
There is provided a method of manufacturing a liquid ejecting head which includes a head main body having nozzles ejecting a liquid supplied via a liquid supply passage, a first supply member having a first liquid supply passage forming a part of the liquid supply passage, a second supply member disposed on a downstream side of the first supply member and having a second liquid supply passage communicating with the first liquid supply passage and forming a part of the liquid supply passage, a filter disposed between the first and second supply members so as to cross the liquid supply passage, and an integrally molded member fixing the first and second supply members by a resin in a state where the filter is nipped between the first and second supply members. The method includes: forming a supporting protrusion protruding toward the filter and supporting the filter on an inner wall surface of at least one of the first and second supply members; and forming the integrally molded member in the state where the filter is nipped between the first and second supply members and a pressure difference is caused between the first and second supply members on both sides of the filter so that a pressure is lower on the side of the supporting protrusion.
US08329085B2 Process for manufacturing a panel made of a thermoplastic composite
A method of manufacturing a panel made of a composite material using a tool having a support on which a lay-up is performed, the lay-up producing a stack of plies of fiber prepregs, followed by consolidating the stack aiming to obtain the panel using a compacting plate arranged above the stack. The method is implemented such that a first set of polyimide films partially covering each other is located in contact with the stack of plies, between the latter and the compacting plate.
US08329083B2 Method of making a lasted skate boot
A method of making a lasted skate boot comprising: (a) providing a male-female mold having male and female sections for defining a mold cavity therebetween, the male section having sides, a rear portion and a bottom portion for defining a three dimensional shape corresponding to the external three dimensional shape of the foot, the female section defining a recess for receiving the male section, the male section comprising a plurality of inner channels for admitting liquid plastic material in the mold cavity; (b) providing a pre-cut sheet made of cloth material laminated to a support made of non-woven fabric; (c) placing the sheet on the male section of the mold such that the non-woven fabric contacts the sides and rear portion of the male section of the mold; (d) closing the male and female sections of the mold; (e) injecting liquid plastic material in the inner channels such that the liquid plastic material spreads on the sheet, pushes the sheet against the recess of the female section of the mold, fills the mold cavity and fuses with the non-woven fabric to form, after cooling, an outer shell comprising a heel portion for surrounding the heel, an ankle portion for surrounding the ankle, and medial and lateral side portions for enclosing the medial and lateral sides of the foot respectively; (f) opening the male and female sections of the mold; and (g) removing the outer shell from the mold.
US08329080B2 Conductive composition, electrophotographic belt, image forming apparatus, and method of manufacturing conductive composition
A conductive composition including a matrix resin comprising a thermoplastic resin, a conductive agent comprising a carbon black having an amine value of 1 to 100 mgKOH/g, and a stiffening agent comprising an acid anhydride, a carboxylic acid, or a compound having an epoxy group.
US08329078B2 Manufacture of an agglomerate consisting of phase change material and having controlled properties
The present invention relates to a process for manufacturing an agglomerate in the form of beads made up of microcapsules of a phase change material, the process comprising wet-granulation and fluidized-bed drying.
US08329077B2 Method of manufacturing aircraft frames in a composite material
The present invention relates to a jig for the manufacture, by means of injection and curing processes, of preforms of composite material frames for aircraft fuselages by using the RTM (resin transfer molding) technology. Two preforms are thus manufactured, one with a C shaped section and another with a L shaped section, together with the preforms of the stabilization ribs for stabilizing the web of the frames and the preform of the roving or staple fiber to cover the gap between the C shaped preform and the L shaped preform. Theses preforms are previously manufactured by any known process for manufacturing preforms. According to a second aspect, the present invention relates to a method of manufacturing composite material load frames for aircraft.
US08329075B2 Method and device for monitoring, documenting, and/or controlling an injection molding machine
A method for monitoring, documenting, and/or controlling an injection molding machine (P) having an injection molding tool (1) into which a melt is introduced, wherein a viscosity of the melt in the injection molding tool (1) is determined directly.
US08329072B2 Method and system for generating sulfur seeds and granules
Sulfur (or sulphur) spray nozzles disposed with a cooling tank spray liquid molten sulfur into the cooling liquid in the tank. Solid sulfur seeds are formed in the cooling liquid and settle in the tank. The cooling tank may be a spiral dewaterer tank that has a screw conveyor at the bottom of the tank that moves the seeds to a granulating drum for enlargement into sulfur granules. The cooling tank may also be used to capture and remove sulfur dust from a slurry of sulfur dust and water recycled from the granulating drum. The sulfur dust in the cooling tank may be captured by contact with molten sulfur droplets streaming down the cooling liquid column such that the dust particles become incorporated into the droplet, thereby being converted to seed. The granulating drum may be equipped with two or more sets of segmented lifting flights. The sets of flights may not be in alignment. The flights may be spaced apart from the inside surface of the drum with segmented rib members. The rib members may allow for the movement of sulfur seeds and granules between the flights and the inside surface of the drum as the drum rotates.
US08329071B2 Multicomponent nanoparticle materials and process and apparatus therefor
Multicomponent nanoparticles materials and apparatuses and processes therefor are disclosed. In one aspect of the disclosure, separate particles generated from solution or suspension or by flame synthesis or flame spray pyrolysis, and the resultant particles are mixed in chamber prior to collection or deposition. In another aspect of the disclosure, nanoparticles are synthesized in stagnation or Bunsen flames and allowed to deposit by thermophoresis on a moving substrate. These techniques are scalable allowing mass production of multicomponent nanoparticles materials and films. The foregoing techniques can be used to prepare composites and component devices comprising one or more lithium based particles intimately mixed with carbon particles.
US08329068B2 Black resin composition, resin black matrix, color filter and liquid crystal display
A black resin composition capable of forming a black matrix having high OD value and high adhesion as well as high resistance is disclosed. The black resin composition is a black resin composition comprising at least a light shielding agent, a resin and a solvent, which light shielding agent contains at least titanium nitride compound particles, wherein the angle of diffraction 2θ of the peak originated from (200) plane of the titanium nitride compound particles when CuKα line is used as the X-ray source is not less than 42.5° and not more than 42.8°. Using this black resin composition allows a thin resin black matrix having a high light shielding property and high resistance to be readily attained.
US08329061B2 Phosphorescent phosphors
Photoluminescent phosphors wherein some of the oxygen anions in the phosphor matrix have been replaced by halides or nitride. In addition, photoluminescent phosphors wherein some of the oxygen anions in the phosphor matrix have been replaced by halides or nitride and a charge compensator has been included. The phosphors are based on green emitting and blue-green emitting aluminates.
US08329059B2 Method for producing organic electroluminescent device, organic electroluminescent device, and electronic apparatus
To provide a method for producing an organic electroluminescent device having luminescent characteristics of high efficiency and prolonged lifetime and in which the occurrence of defects is suppressed, the organic electroluminescent device, and an electronic apparatus. A method for producing an organic electroluminescent device including a first electrode, a second electrode, and a functional layer disposed between the first electrode and the second electrode, the functional layer including at least a luminescent layer, the method includes the steps of mixing a solvent and a functional material to produce a functional solution; and applying the functional solution to form the functional layer by a wet film formation process, wherein, before the functional solution is produced, the solvent is subjected to dehydration and deoxygenation in order to remove water and oxygen in the solvent.
US08329057B2 Working liquid for latent heat transport apparatus and method for operating latent heat transport apparatus
A method for operating a latent heat transport apparatus by providing a working liquid for a latent heat transport apparatus, which includes a compound of the formula C6F13C2H5 at an operation temperature of from −50 to 200° C.
US08329052B2 Imprint lithography
A method of making an imprint template includes providing a transfer layer on a substrate and providing a layer of imprintable medium on the transfer layer, using a master imprint template to imprint a pattern into the imprintable medium, polymerizing the imprintable medium by exposing it to actinic radiation, then etching the resulting polymer layer, the transfer layer and the substrate such that the imprinted pattern is transferred to the substrate, the substrate thereby becoming an imprint template bearing a pattern which is the inverse of a pattern provided on the master imprint template.
US08329050B2 Substrate processing method
A substrate processing method for processing a substrate, on which a processing target layer, an intermediate layer, and a mask layer having an opening to expose a part of the intermediate layer are stacked in this order, includes a shrink etching step. In the shrink etching step, an opening width of the opening of the mask layer is reduced by depositing deposits on a sidewall surface thereof by a plasma generated from a gaseous mixture of depositive gas expressed by a general formula CxHyFz (x, y and z being positive integers) and SF6 gas. Also, there is formed in the intermediate layer an opening having an opening width corresponding to the reduced opening width of the opening of the mask layer by etching the intermediate layer.
US08329043B2 Method and device for treating a liquid
In a method of treating a liquid, a liquid to be treated is introduced into a space, a mechanical cavitation element acts upon the liquid while gas is supplied into the region of the surface of the cavitation element and introduces the gas into the liquid by moving the cavitation element, and sound waves are introduced directly into the liquid by at least one acoustic power transducer.
US08329037B2 Filter apparatus and method of removing organic waste
A filtration apparatus including an annular filter surrounding a waste treatment chamber, a first turbine drawing liquid up within the chamber and a second turbine driving liquid outwardly through the filter. In the method of treating organic waste, the chamber includes an ultraviolet lamp and a cylindrical baffle surrounding the chamber having a mirrored surface. The disclosed apparatus further includes anodic and cathodic plates surrounding the filter.
US08329025B2 Analyte determination method and analyte meter
The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.
US08329024B2 Electrochemical device and method for long-term measurement of hypohalites
A method and apparatus measures the presence of total residual oxidant species in aqueous environments. More specifically, the apparatus is operable to measure hypohalites (e.g., hypochlorite and hypobromite) in water containing halide salts using electrochemistry. The apparatus can be a sensor having four electrodes—a reference electrode, a working electrode, and two auxiliary electrodes. The fourth electrode, i.e., the second auxiliary electrode, can be used to generate ionized water near and in contact with the working electrode. The ionized water can clean the working electrode to minimize effects due to scaling or biofilm formation. As such, the working electrode does not need the capability to clean itself. Thus, other elements, originally believed to be unsuitable for use in saline aqueous environments, can be used for the electrodes, for example, gold.
US08329023B2 Method for quantifying a chemical substance with substitutional stripping voltammetry and a sensor chip used therefor
The purpose of the invention is to provide a method for quantifying a chemical substance with high accuracy using substitutional stripping voltammetry and a sensor chip used therefor.A sensor chip comprising a stripping electrode which is covered with stripping gel and a method utilizing the sensor chip. A reaction represented by the following formula (III) occurs at the stripping electrode. [Chem. 3] Ag+X⊖→AgX↓+e⊖  (III)
US08329020B2 Method of shutting down water electrolysis system
A water electrolysis system includes a water electrolysis apparatus for electrolyzing pure water supplied from a pure water supply apparatus to produce high-pressure hydrogen. A pressure releasing device is connected between a pipe of the water electrolysis apparatus and a check valve connected to the inlet port of a gas-liquid separator, for releasing the pressure of the high-pressure hydrogen from the water electrolysis apparatus independently from the gas-liquid separator. The pressure releasing device has a bleeder passage including a pressure reducing valve and a solenoid-operated valve.
US08329016B1 Microfluidic device having an immobilized pH gradient and PAGE gels for protein separation and analysis
Disclosed is a novel microfluidic device enabling on-chip implementation of a two-dimensional separation methodology. Previously disclosed microscale immobilized pH gradients (IPG) are combined with perpendicular polyacrylamide gel electrophoresis (PAGE) microchannels to achieve orthogonal separations of biological samples. Device modifications enable inclusion of sodium dodecyl sulfate (SDS) in the second dimension. The device can be fabricated to use either continuous IPG gels, or the microscale isoelectric fractionation membranes we have also previously disclosed, for the first dimension. The invention represents the first all-gel two-dimensional separation microdevice, with significantly higher resolution power over existing devices.
US08329014B2 Vehicle body production method
Disclosed is a method for producing a vehicle body, which, without removing protrusions on an electrophoretic coating, improves the coating quality. The outer surface of the vehicle body is sanded prior to a pre-treatment, where the vehicle body is degreased and washed.
US08329011B2 Polymerase-immobilized electrode
The present invention is to reduce a false signal in an apparatus for electrochemically decoding a base sequence of DNA, which false signal is caused by a phenomenon that even unreacted nucleotide 5′-triphosphate derivatives remaining in the solution are electrochemically converted on an electrode. The present invention provides a polymerase-immobilized electrode that comprises an electroconductive substrate and a polymerase unit immobilized on the surface of the electroconductive substrate, wherein the polymerase unit comprises a polymerase part, an anchor part and an electroconductive part, which are linked in an order of the polymerase part, the anchor part and the electroconductive part, or in an order of the polymerase part, the electroconductive part and the anchor part; and the polymerase unit is immobilized on the electroconductive substrate by the anchor part; wherein a free end of the electroconductive part, not immobilized on the electroconductive substrate, is located in the vicinity of an active site of the polymerase part.
US08329009B2 High throughput screening of ion channels
Multi-well plates having contoured well designs allow multi-stage high throughput parallel assaying of ion channels or ion transporters. A well of a multi-well plate has a bottom region that is sized and shaped to simultaneous accommodate a sensing electrode and a pipette for delivering, e.g., test compounds, wash fluid, and optionally ligands. Such multi-well plates may be coupled with an instrument having a pipette head and an electrode plate. Such arrangement facilitates fluidic contact between cells and fluids provided via a pipette. It also facilitates washing of wells with buffers or other wash solutions to allow serial exposure of test cells to various reagents or other stimuli. Generally, the design allows control and test experiments to be performed on the same cell (or cells) in a single well.
US08329006B2 Electroplating cell with hydrodynamics facilitating more uniform deposition across a workpiece during plating
An apparatus for establishing more uniform deposition across one or more faces of a workpiece in an electroplating process. The apparatus employs eductors in conjunction with a flow dampener member and other measures to provide a more uniform current distribution and a more uniform metal deposit distribution as reflected in a coefficient of variability that is lower than conventional processes.
US08329004B2 Polymeric, non-corrosive cathodic protection anode
An apparatus for protection of metallic materials from corrosion comprising an electrical power source (5) and a conductor (7) coupled to the power source. An anode (11) is electrically coupled to the conductor. The anode is configured to be secured proximal to the metallic materials to be protected from corrosion and has an exterior surface (13) formed predominantly of electrically conductive polymer and an interior filled with particulate carbonaceous material. The anode comprises a hollow cylinder (13) formed of electrically conductive polymer, the cylinder having an interior. A metallic tube (15) is secured to and in electrical communication with the interior of the cylinder. An anode conductor (17) is electrically coupled to the metallic tube and extends from the interior of the cylinder to the exterior of the cylinder for connection to the conductor coupled to the power source.
US08329003B2 System and method for detecting and preventing galvanic corrosion
A system for detecting and preventing galvanic corrosion of an anodic metal includes a potential detector configured to monitor an electrical potential within the electrolyte solution, a signal amplifier coupled with the potential detector, and a current delivery circuit coupled with the signal amplifier. The signal amplifier is configured to provide an output proportional to the monitored electrical potential, and the current delivery circuit is configured to provide a current to a cathodic metal that is proportional to the output of the signal amplifier.
US08329002B1 Thin films and methods and machines for forming the thin films
Methods for depositing an amorphous vanadium oxide (VOx) film include vaporizing vanadium from a vanadium source while the a gas containing an oxygen species and a process modifying additive are in the chamber so as to deposit an amorphous VOx film on the substrate, where x>0. The process modifying additive includes a gas flowing into the chamber or vaporized material from a target source. The additive may stabilize the deposition rate of VOx, reduce resistivity, improve thickness control, and improve uniformity of thickness and resistivity. The thin film may be a nitrogen-enhanced, amorphous vanadium oxide (VOxNy) film formed on a substrate, where x>y>0, and the film contains at least 0.2 atomic % nitrogen. The film may be used in a device, such as a thermal or infrared sensor, or more particularly a bolometer.
US08328999B2 Method for controlling film forming apparatus, film forming method, film forming apparatus, organic EL electronic device, and storage medium having program for controlling film forming apparatus stored therein
A material having a low work function is quickly inserted near an interface between an organic layer and a cathode. A sputtering apparatus (Sp) includes a target material formed of silver (Ag), a dispenser formed outside a processing container and evaporating cesium (Cs) having a lower work function than silver (Ag) by heating the cesium (Cs), a first gas supply pipe communicating with the dispenser to transfer evaporated cesium (Cs) to the processing container by using argon gas as a carrier gas, and a high frequency power supply source supplying high frequency power to the processing container. A controller generates plasma by exciting the argon gas by using energy of the high frequency power, and while forming a metal electrode by using an silver (Ag) atom, wherein the Ag atom is generated from a the target material by using the generated plasma, controls a ratio of the cesium (Cs) mixed with the metal electrode.
US08328994B2 Ethanol recovery system for cellulosic feedstocks
Processes for the recovery of ethanol, useful as a fuel, from various cellulosic feedstock materials fermented to produce ethanol-containing beer are disclosed. The present invention provides a method and a system for ethanol recovery from highly viscous fermented citrus waste biomass. The systems overcome various challenges, including effectively stripping the ethanol from biomass beer in an energy efficient and economical manner that may allow for the further dehydration of the ethanol/water mix in a traditional rectifier distillation column. In certain embodiments, a series of flash stages and beer stripping columns are capable of operating with highly viscous slurries and/or feedstocks containing high levels of solids.
US08328993B2 Pyrolysis reactor for processing municipal wastes
Proposed is a pyrolysis reactor for processing solid municipal and domestic wastes by means of a pyrolytic reaction in the pyrolysis chamber without access of oxygen to the reaction system. The reactor is characterized by containing two waste-feeding screws which have tapered shapes, a gap between the outer surfaces of the threads, are inclined in the vertical plane and converge towards each other in a horizontal plane in the direction from the inlet to the outlet end. The gap is adjustable with diminishing toward the outlet end.
US08328992B1 Retort
A retort involves a stack of retort units arranged to process coal or other raw material by heating the coal in a heating compartment and directing vapors emitted from the raw material into a vapor compartment surrounding the heating compartment. The heating compartment may include a plurality of louver units with embedded heating components. Each louver unit includes heating fins (a heat transfer medium) that delivers heat to the coal. Each louver unit also includes an insulation layer adjacent a vapor opening where vapors emitted from the coal pass into the vapor compartment. The vapors are directed to a distillation column where carbon based vapors, volatiles, fuel vapors and the like may be liquefied for transport to a refinery or directly refined into fuels. Further, a clean coal char (toxins and carbon vaporized) is delivered to a power generation plant to provide cleaner emissions relative to unprocessed coal.
US08328991B2 Thermal conversion of organic matter into usable by-products
A processing vessel is loaded with a feedstock including organic material and at least one additive which is non-inert to the organic material. A bottom portion of the feedstock is heated to a pyrolytic state for producing a horizontal thermal layer within the feedstock which thermally decomposes organic material into carbon as the non-inert additive reacts with the organic material. Vapor is directed downwardly through the feedstock while discharging volatile organic compounds from a lower portion of the chamber. Prior to complete thermal decomposition of the feedstock, the direction of vapor flow within the feedstock is reversed wherein the vapor flows upwardly through the feedstock while the volatile compounds are discharged from an upper portion of the chamber. Pressure and vapor flow within the chamber are regulated during upward vapor flow to regulate vertical movement of the thermal layer within the feedstock for controlling the extent of thermal decomposition of the feedstock.
US08328988B2 Reduction of the adsorption of quaternary ammonium salts onto cellulosic fibers
A product comprising cellulosic fibers, 0.0001 to 0.03 moles of a water soluble metal salt per 100 grams of cellulosic fiber, based on the oven dry weight of the cellulosic fiber, water and a quantity quaternary ammonium salt to provide 100 to 3000 ppm of quaternary ammonium salt in solution. A process for making the product.
US08328986B2 Laminated sheet, method of producing the sheet, exhaust gas processing device, and method of producing the device
A disclosed laminated sheet to be wound around an outer surface of an exhaust gas processing unit includes a first mat containing first inorganic fibers and a second mat containing second inorganic fibers, the second mat being laminated on the first mat. The average fiber length of the first inorganic fibers is larger than the average fiber length of the second inorganic fibers and the laminated sheet is to be wound around the exhaust gas processing unit such that the first mat forms an outermost layer. Development of cracks in the outer surface of the laminated sheet can be prevented by winding the laminated sheet around an exhaust gas processing unit such that the first mat faces outward.
US08328985B2 Method of making a fabric-creped absorbent cellulosic sheet
A method of making a fabric-creped absorbent cellulosic sheet includes compactively dewatering a papermaking furnish to form a nascent web having an apparently random distribution of papermaking fiber, applying the nascent web having the apparently random fiber distribution to a translating transfer surface that is moving at a transfer surface speed, and fabric-creping the web from the transfer surface at a consistency of from about 30 to about 60 percent utilizing a patterned creping fabric, the fabric-creping step occurring under pressure in a fabric creping nip defined between the transfer surface and the creping fabric, the web being creped from the transfer surface and wherein the creping fabric is adapted to contact the transfer surface and applies pressure to the web against the transfer surface such that the fibers of the web are redistributed on the creping fabric to form a web with a drawable reticulum.
US08328981B2 Method for heating a focus ring in a plasma apparatus by high frequency power while no plasma being generated
A plasma etching apparatus includes a vacuum processing chamber; a lower electrode, i.e., a mounting table for mounting the substrate, provided in the vacuum processing chamber; an upper electrode provided to face the lower electrode; a gas supply unit for supplying a processing gas to the vacuum processing chamber; a high frequency power supply unit for supplying a high frequency power to the lower electrode; and a focus ring provided on the lower electrode to surround a periphery of the substrate. In a method for performing a plasma etching on a substrate by using the plasma etching apparatus, a plasma is generated in the vacuum processing chamber to perform the plasma etching on the substrate by using the plasma after the focus ring is heated by supplying a high frequency power from the high frequency power supply unit to the lower electrode under a condition that no plasma is generated.
US08328979B2 Composition for structural adhesive
The invention relates to a composition for an acrylic structural adhesive containing a mixture of block copolymers, of elastomer and of elastomeric polymer particles.
US08328972B2 Process for the production of a foamed article
The foamed article is produced starting from a core layer (1) which comprises a flexible, open-cell foam having voids forming at least 90% of the volume of the open-cell foam. The core layer (1) is applied in a mold (6, 8), optionally together with an upper (3) and/or a lower cover layer (2), between a lower (5) and an upper mold surface (9) thereof. The mold (6, 8) is closed and a curable, foamable composition (7) is allowed to foam in the mold to produce a further foam filling the voids of the open-cell foam. In order to enable to use less foamable composition (7) to fill the voids of the open-cell foam, the core layer (1) is laid onto the lower mold surface (5) and the foamable composition (7) is sprayed onto the core layer (1) lying onto the lower mold surface so that the foamable composition (7) can penetrate at least partially by gravity into the open-cell foam core layer (1). Moreover, the foamable composition (7) has a dynamic viscosity, measured at a shear rate of 1/s, of lower than 1000 mPa·s when arriving onto the core layer (1).
US08328967B2 Nano-laminate-based ignitors
Sol-gel chemistry is used to prepare igniters comprising energetic multilayer structures coated with energetic materials. These igniters can be tailored to be stable to environmental aging, i.e., where the igniters are exposed to extremes of both hot and cold temperatures (−30 C to 150 C) and both low (0%) and high relative humidity (100%).
US08328960B2 High strength bainitic steel for OCTG applications
A high strength bainitic steel and a process for producing seamless pipes for OCTG applications are described. In particular, the advantages ensuing to the steel of the invention are the improvement in strength-toughness over tempered martensitic steels, and a simplified thermal treatment. Quenching is not necessary and by avoiding the quenching treatment the microstructure results far more homogeneous, which allows thick walled tubes to be produced. For the same steel composition, in comparison to conventional tempered martensitic structures, a better combination of strength and toughness can be achieved, in particular by tempering as rolled carbide-free bainitic structures.
US08328957B2 Electric resistance welded steel pipe with excellent weld toughness for line pipe
In an electric resistance welded steel pipe with excellent weld toughness for a line pipe, the area fraction of minute defects each having a maximum length of less than 50 μm in a projection plane of an electric resistance welded seam is in the range of 0.000006 to 0.026, and the absorbed energy at −40° C. measured by a method for an impact test of metallic materials is 315 J or more.
US08328956B2 Carbonitrided induction hardened steel part superior in surface fatigue strength at high temperature and method of production of same
The present invention provides a gear, continuously variable transmission, constant velocity joint, hub, or other steel part superior in surface fatigue strength compared with the past and method of production of the same, that is, provides a carbonitrided induction hardened steel part made of steel comprised of a specific composition of chemical ingredients and carbonitrided, then treated by induction hardening, the steel part characterized in that a surface N concentration is 0.1 to 0.8 mass %, a sum of an N concentration and C concentration is 1.0 to 2.0 mass %, an amount of surface residual austenite is less than 15 vol %, a depth of the incompletely hardened layer from the surface is less than 5 μm, and a surface X-ray diffraction half width is 6.0 degrees or more, and a method of production of the same.
US08328955B2 Process for producing composite magnetic material, dust core formed from same, and process for producing dust core
A composite magnetic material is manufactured having magnetic properties that can excellently cope with the decreasing size and increasing electric current of magnetic elements, such as choke coils, and can be used in a high frequency range, a dust core using the composite magnetic material, and a method of manufacturing the same. The dust core includes magnetic metal powder and an insulating material, in which the magnetic metal powder has a Vickers hardness (Hv) of 230 ≦ Hv≦ 1000, the insulating material has a compressive strength of 10000 kg/cm2 or lower and is in a mechanical collapsed state, and the insulating material in a mechanical collapsed state is interposed in the magnetic metal powder.
US08328954B2 Method of manufacturing permanent magnet
Crystal fractured surfaces of raw meal powder having more equal crystal orientation relationship in the magnetic field are arranged to be assembled together so that a method of manufacturing a permanent magnet which has an extremely high degree of orientation can be provided. In this invention, raw meal powder (P) is filled into a cavity, the raw meal powder (P) is oriented in the magnetic field while being pressed or urged by pressing means that has a smaller area than the cross-sectional area of the cavity. Semi-finished product thus oriented is compression-molded into a predetermined shape in the magnetic field.
US08328952B2 Method of perfuming
A method of perfuming in automatic dishwashing comprising the step of providing a first perfume into an automatic dishwashing machine wherein the first perfume is capable of generating a second perfume comprising from about 0.001% to about 10% by weight thereof of a sulphurous compound.
US08328950B2 Foreign material contamination detection
There are provided a system, method and computer program product for detecting foreign materials in a semiconductor manufacturing process. The manufacturing process uses a plurality of semiconductor manufacturing tools. The system categorizes at least one monitoring wafer according to one or more categories. The system supplies the categorized monitoring wafer to a semiconductor manufacturing tool. The system observes a level of contamination on the categorized monitoring wafer. The system compares the level of contamination to a threshold. The system cleans the tool in a response to determining that the level of contamination is larger than the threshold. The system determines which category of the wafer leaves a highest level of contamination on the tool. The system identifies a root cause of the highest level of contamination on the tool.
US08328943B2 Film forming apparatus and method
A film forming apparatus includes a processing chamber inside which a vacuum space is maintained and to which a film forming gas is supplied, a substrate supporting unit which is disposed inside the processing chamber and supports a substrate, and a heater which is made of a compound material comprising a high-melting point metal and carbon, is disposed inside the processing chamber, and heats the substrate.
US08328939B2 Diffuser plate with slit valve compensation
The present invention generally comprises a diffuser plate for a PECVD chamber. The diffuser plate comprises a plurality of hollow cathode cavities. The edge of the diffuser plate that will reside closest to a slit valve within a processing chamber may have the shape and/or size of the hollow cathode cavities adjusted to compensate for the proximity to the slit valve. By adjusting the shape and/or size of the hollow cathode cavities closest to the slit valve, the diffuser plate may permit a uniform plasma distribution across the processing chamber and thus, a uniform film thickness upon a substrate during a PECVD process.
US08328938B2 Buffer apparatus and thin film deposition system
A buffer apparatus and a thin film deposition system are provided. The buffer apparatus is connected between a liquid material supply apparatus and a deposition machine. The buffer apparatus includes a container and a baffle. The container is used for containing a liquid material supplied from the liquid material supply apparatus. The top of the container has an input hole and an output hole. The baffle is disposed in the container and located under the input hole.
US08328936B2 Producing a diamond semiconductor by implanting dopant using ion implantation
A process of producing a diamond thin-film includes implanting dopant into a diamond by an ion implantation technique, forming a protective layer on at least part of the surface of the ion-implanted diamond, and firing the protected ion-implanted diamond at a firing pressure of no less than 3.5 GPa and a firing temperature of no less than 600° C. A process of producing a diamond semiconductor includes implanting dopant into each of two diamonds by an ion implantation technique and superimposing the two ion-implanted diamonds on each other such that at least part of the surfaces of each of the ion-implanted diamonds makes contact with each other, and firing the ion implanted diamonds at a firing pressure of no less than 3.5 GPa and a firing temperature of no less than 600° C.
US08328934B2 Crystal of GTP Cyclohydrolase Type IB
This invention relates to a novel, bacterial GTP Cyclohydrolase Type IB enzyme, and the crystal structure thereof.
US08328933B2 Apparatus and semiconductor co-crystal
The invention provides a method to enforce face-to-face stacking of organic semiconductors in the solid state that employs semiconductor co-crystal formers (SCCFs), to align semiconductor building blocks (SBBs). Single-crystal X-ray analysis reveals π-orbital overlap optimal for organic semiconductor device applications.
US08328930B2 Pigment preparation, method for producing the same and its use
Pigment preparation containing at least one pigment and at least one compound of the general formula CH3—(CH2)n—CH2—O—[(CH2)p—O]m—H. The pigment preparation can be produced by dispersing and drying.It can be used for coloration and/or antistaticization in waterborne color and varnish systems, emulsion paints, printing inks, liquid-ink systems and coating systems.
US08328926B2 Ink jet recording ink, ink jet image-forming method and ink jet recording apparatus
The invention provides an ink jet recording ink containing a self-dispersion pigment having a lactone group and a carboxyl group, an organic carboxylic acid salt, water and a water-soluble substance having a coefficient of hydrophilicity-hydrophobicity of 0.37 or more as defined by the following equation (A), and having a surface tension of 34 mN/m or less. Coefficient of hydrophilicity-hydrophobicity=[(Water activity value of a 20% aqueous solution)−(Molar fraction of water in the 20% aqueous solution)]/ [1−(Molar fraction of water in the 20% aqueous solution)]  Equation (A)
US08328922B2 Postal blue ink with high reliability
A water-based ink for inkjet recording exhibits a blue color defined as L*<45, 25
US08328921B2 Dye-based gray ink formulations, methods of making dye-based gray ink formulations, and ink-jet ink sets
Dye-based gray ink formulations, ink-jet ink sets, and methods of making a dye-based gray ink formulation, are disclosed.
US08328919B2 Electroless deposition solutions and process control
One embodiment of the present invention is a method of electroless deposition of cap layers for fabricating an integrated circuit. The method includes controlling the composition of an electroless deposition bath so as to substantially maintain the electroless deposition properties of the bath. Other embodiments of the present invention include electroless deposition solutions. Still another embodiment of the present invention is a composition used to recondition an electroless deposition bath.
US08328916B2 Filter device for hydrocarbon adsorption
A hydrocarbon adsorption filter device comprising: a filter housing; at least one filter element with activated carbon arranged in the filter housing; an intake canal, connecting the filter housing with an environment, wherein fresh air is taken in during a flushing operation; and an intake canal housing cover, wherein the intake canal housing cover includes a labyrinthine canal structure having a first end and an opposing second end, wherein the first end is in communication with the intake canal while the second end is in communication with a floor-side opening of the housing.
US08328913B2 Flammable gas concentration system
A flammable gas concentration system is described, which includes a concentrating apparatus for acquiring at least a portion of the product gas, concentrating the flammable gas included in the acquired product gas, and generating a high-concentration gas; and a mixer for acquiring the raw gas and the high-concentration gas generated by the concentrating apparatus, mixing the acquired high-concentration gas and the raw gas, and generating the product gas.
US08328912B2 Air dryer for electrical enclosures
An air dryer having an internal orifice designed into an outlet end cap that eliminates the need for external valves or regulators to control the flow of air through the dryer. The internal orifice, which can be press-fit or threaded into the end cap, provides a consistent and stable outlet flow and dew point and eliminates the need for instruments to measure outlet flow and dew point. The orifice size can be easily changed for changing outlet flow and dew point. A protective tubular shroud is provided for shielding a membrane module of the dryer, and for routing sweep gas to a bottom vent.
US08328911B2 Method for removing CO2 from coal-fired power plant flue gas using ammonia as the scrubbing solution, with a chemical additive for reducing NH3 losses, coupled with a membrane for concentrating the CO2 stream to the gas stripper
A method for removing and capturing carbon dioxide from a fluid stream includes the steps of exposing the fluid stream to an aqueous scrubbing solution that removes and holds carbon dioxide from the fluid stream, passing the aqueous scrubbing solution through a membrane in order to separate excess water from the scrubbing solution and increase the concentration of carbon dioxide in the scrubbing solution, heating the scrubbing solution having an increased concentration of carbon dioxide so as to release carbon dioxide gas and recycling the scrubbing solution. A carbon dioxide capture apparatus includes a carbon dioxide scrubber, a membrane downstream from the scrubber for separating water and concentrating carbon dioxide in a scrubbing solution and a stripper vessel.
US08328908B2 Sorbent composition
The invention provides an apparatus and methods for removing heavy metals and heavy metal-containing compounds from fluid streams. The invention also provides new uses and methods for removing heavy metals and heavy metal-containing compounds from a natural gas stream, or a gas stream produced during the combustion or gasification of a fossil fuel, such as coal or petroleum fuels or oil.
US08328904B2 Method and system for control of desiccant dehumidifier
An active wheel desiccant dehumidifier is controlled for improved energy savings by modulating operation characteristics including process air flow, reactivation air flow, temperatures, and wheel rotation in response to changing conditions.
US08328900B2 Processes for recovering metals from aqueous solutions
Provided herein are processes for recovering molybdenum and/or other value metals (e.g., uranium) present in aqueous solutions from a large range of concentrations: from ppm to grams per liter via a solvent extraction process by extracting the molybdenum and/or other value metal from the aqueous solution by contacting it with an organic phase solution containing a phosphinic acid, stripping the molybdenum and/or other value metal from the organic phase solution by contacting it with an aqueous phase strip solution containing an inorganic compound and having a ≦1.0 M concentration of free ammonia, and recovering the molybdenum and/or other value metal by separating it from the aqueous phase strip solution. When the molybdenum and/or other value metal are present only in low concentration, the processes can include an organic phase recycle step and/or an aqueous phase strip recycle step in order to concentrate the metal prior to recover.
US08328895B2 Filter media pleat pack retention
An approach that provides filter media pleat pack retention is described. In one embodiment, filter media pleat pack retention is attained by providing a filter media pleat pack having a joining member located between a first filter media portion and a second filter media portion. The first filter media portion is coupled to the joining member at one side and the second filter media portion is coupled to the joining member at an opposite side. The joining member provides stiffness to the filter media pleat pack and provides support to the panel stopping excessive bowing under high pressure and subsequent tearing and puncture.
US08328894B2 Dust prevention and removal device
A device is provided that is capable of circulating air throughout a personal space as well as collecting and preventing the build up of dust and other particulate matter by drawing in air from the surrounding environment and removing some dust, allergens and other such particulate matter therefrom. The filtered air is then expelled out of the device and back into the surrounding environment. The device includes a housing defining an interior space having a motor and fan assembly disposed therein. The housing includes an inlet with a filter provided therein such that air drawn in through the inlet is filtered. The air is then expelled through a circumferentially disposed outlet. The filter element preferably includes a lock and key system configured to prevent operation of the device in the absence of a properly keyed filter.
US08328888B2 Engineered fuel storage, respeciation and transport
Techniques, systems and material are disclosed for thermochemical regeneration of biomass into renewable engineered fuel, storage of the renewable engineered fuel, respeciation of the renewable engineered fuel and transport. In one aspect, a method includes generating low density hydrogen fuel from biomass dissociation at a first location of a low elevation. The low density hydrogen fuel is self-transported in a pipeline to a second location at a higher elevation than the first location by traveling from the first location to the second location without adding energy of pressure. A high density hydrogen carrier is generated at the second location of higher elevation by reacting the low density hydrogen fuel with at least one of a carbon donor, a nitrogen donor and an oxygen donor harvested from industrial waste. The high density hydrogen carrier is delivered to a third location of a lower elevation than the second location while providing pressure or kinetic energy.
US08328887B2 Method and system for producing synthetic gas from biomass by high temperature gasification
A method for producing synthetic gas from biomass by high temperature gasification, by: feeding biomass, carbonizing to yield pyrolysis gas and charcoal, pulverizing the charcoal, and gasifying in a gasifier. The heat source for the carbonizing step comes from a direct combustion reaction between external combustible gas and external oxygen in a carbonization furnace. Also provided is a device for producing synthetic gas from biomass by high temperature gasification, containing at least: a supercharging feeding system for biomass, a carbonization furnace containing at least a burner nozzle, a pulverizing system, a transportation system for charcoal powder, a gasifier, a pneumatic conveying system, and a plurality of connecting pipes therefor; the burner nozzle of the carbonization furnace is connected to an external combustible gas pipe and an external oxygen pipe respectively.
US08328886B2 Fuel processor having temperature control function for co shift reactor and method of operating the fuel processor
A fuel processor includes a reformer that generates hydrogen gas by reacting a fuel source and water; a burner that heats the reformer to a temperature suitable for a hydrogen generation reaction; a CO shift reactor that removes CO generated during the hydrogen generation reaction in the reformer; a heating element for heating the CO shift reactor; and a cooling element for cooling the CO shift reactor, wherein the cooling element comprises at least one of a cooling water flow line for heat exchange with the CO shift reactor when cooling water flows through the cooling water flow line and a cooling gas flow line for heat exchange with the CO shift reactor when a cooling gas, which is a burner exhaust gas that has heat exchanged with cooling water, flows through the cooling gas flow line. When the fuel processor is operated, a stable CO removal performance can be maintained since the temperature of the CO shift reactor can be actively controlled.
US08328881B2 Hair treatment composition
This invention relates to a permanent dye for coloring keratinous fibers comprising: (a) A solution of iron (II) or iron (III) salt; (b) A solution of an aqueous extract of Terminalia chebula and (c) A solution of at least one color developer selected from the group consisting of a polyphenol and polyphenol derivatives or mixture thereof. A method of coloring keratinous fibers using the permanent dye is also provided.
US08328878B2 Yarn of animal collagen fiber and manufacture process thereof
A kind of yarn of animal collagen fiber and the manufacture process thereof, characterized in that the yarn is made of 1-100 WT % of collagen fiber of animal leather, and 0-99 WT % of textile fiber. The yarn of animal collagen fiber is made by the following procedure: choosing raw materials, loosing fiber, assorting, blending, carding, drawing, and twisting, if using the rawhide, the above procedure should add the steps of liming, washing, deliming, tanning and dehydrating. The raw material of the yarn can be the rawhide of any animal, as well as the leftover material or worn-out leather. The yarn has excellent properties, high tensile strength, abrasion resistance, softness, water adsorbent, oil adsorbent, flame-retardant, and can be woven, knitted and braided. The yarn can be used to weave high quality fabric with high count and high strength for four seasons, which greatly broadens the application fields of animal leather, improves the utilization of the leather and provides a kind of spinnable fiber for the textile industry. Therefore, the present invention can be widely used in textile industry.
US08328877B2 Stent retention element and related methods
In one embodiment, the invention is directed to a stent retention element having an elastic member adapted to be incorporated with a first end of an elongate stent and to coil toward a second end of the elongate stent to anchor the elongate stent at an anatomical site. According to one feature, the stent retention element expands and compresses to effectively lengthen and shorten, respectively, the stent to accommodate ureter lengthening and shortening.
US08328873B2 Knee joint prosthesis system and method for implantation
A prosthesis system for replacing a knee joint between a femur and a tibia can include a femoral component, a tibial component, a bearing, a first yoke, and a first key. The femoral component can include a first condylar portion, a second condylar portion, a first sidewall extending superiorly from the first condylar portion, a second sidewall extending superiorly from the second condylar portion where the first and second sidewalls collectively comprise a first hinge portion. The tibial component can have a bone engaging inferior surface and a bearing engaging superior surface. The bearing can have an inferior that engages the bearing engaging surface and a superior femoral engaging surface. The bearing can define an opening. The first yoke can have an inferior portion, a superior portion and a yoke keyway extending through the therethrough.
US08328870B2 Stand-alone interbody fixation system
A stand-alone interbody fixation system having a cage, anterior fixation blade and posterior fixation blade. The cage includes an annular side wall with an open interior and upper and lower surfaces, the cage being configured to fit between end plates of adjacent vertebrae. The anterior fixation blade includes an anterior alignment boss with two opposing outward extending anterior blades with end plate penetrating tips configured to fit within the open interior of the cage. The posterior fixation blade includes a posterior alignment boss with two opposing outward extending posterior blades with end plate penetrating tips configured to fit within the open interior of the cage. The anterior alignment boss and posterior alignment boss being rotatably coupled to each other and with a first opening and a second opening in the annular side wall opposite the first opening. The anterior and posterior fixation blades are counter-rotating blades and the anterior alignment boss and posterior alignment boss are configured to receive or engage a blade activation tool having an anterior engagement portion and a posterior engagement portion configured to rotate the anterior and posterior fixation blades from a stowed position to a deployed condition.
US08328868B2 Medical devices and delivery systems for delivering medical devices
Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
US08328866B2 Method and apparatus for radical prostatectomy anastomosis including an anchor for engaging a body vessel and deployable sutures
A device for joining a first body vessel to a second body vessel including a cartridge having a distal end and defining a longitudinal axis, a radially expandable anchor disposed at the distal end of the cartridge for engaging the first body vessel, the expandable anchor having an initial condition and an expanded condition wherein the expandable anchor is radially larger than the expandable anchor in the initial condition, and a plurality of sutures disposed within the cartridge and being deployable therefrom so as to engage the second body vessel, the sutures being threaded through the expandable anchor.
US08328865B2 Highly flexible stent and method of manufacture
Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding having interconnected struts joined at vertices, and having bridges connecting sections of the helical winding to each other. An annular ring can be provided at one or both ends of the helical winding, and the annular ring can have extensions extending to connect to the helical winding. One of the extensions can connect to a bridge and another extension can connect to a vertex. The struts at the ends of the helical winding can have strut lengths that differ from the strut lengths of the struts in a central portion of the winding between the ends of the winding.
US08328863B2 Optimal ratio of polar and bending moment of inertia for stent strut design
An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery.
US08328862B2 MRI compatible vascular occlusive devices and related methods of treatment and methods of monitoring implanted devices
Implantable aneurysm-sac treatment devices include an implantable coil body configured and sized to reside in a sac of an aneurysm. The body has an inductance and capacitance. The capacitance is selected so that the coil resonates at a Larmor frequency of a predefined magnetic field strength.
US08328861B2 Delivery system and method for bifurcated graft
A delivery system and method for delivering a bifurcated intracorporeal device. The delivery system comprises a shaft having a distal section supporting a primary support member positioned to be disposed within at least a primary portion of the bifurcated intracorporeal device and a secondary support member extending within a secondary portion of the bifurcated intracorporeal device. At least one belt is configured to be circumferentially disposed about a portion of the secondary support member so to at least partially constrain the secondary portion of the bifurcated intracorporeal device. A tube defining a lumen is secured relative to the secondary support member. A release member is configured to engage and releasably secure the belt in a constraining configuration. The release member extends through at least a portion of the tube lumen such that the release member is accessible adjacent a proximal end of the tube.
US08328860B2 Implant including a coil and a stretch-resistant member
This invention is directed to implantable coils and, more particularly, to a coil implant having a stretch-resistant member internal to the coil. The implant of the invention is able to freely articulate and torque prior to delivery. Once delivered, the implant is no longer stretch resistant and is therefore able to substantially conform to the vascular site.
US08328859B2 Forced air warming unit
A forced air warming unit has a casing with inlet and outlet openings. The casing encloses a scroll housing with a curved inside surface in which a blower is disposed. A circuit board in the casing encloses the blower in the scroll housing. At least one opening penetrates the circuit board. A heater plate is disposed between the circuit board and the blower. The blower draws air through the inlet opening, along a first side of the circuit board through the at least one opening into the scroll housing. The blower also forces air along a second side of the circuit board which faces the scroll housing, through air passages in the circuit board, along the first side through the at least one opening, into the scroll housing. The blower accelerates air along the curved inside surface and past the heater plate. Heated, pressurized air exits through the outlet opening.
US08328855B2 Osteosynthesis device with rapid fixing means
The invention relates to an osteosynthesis device having a plate (10) which includes a recess (12) which defines an inner edge (22) and receives ring (14) designed to receive the pin (20). According to the invention, the plate (10) has a threaded opening (26) on the edge of the recess (12), which opens into the inner edge (22), while the ring (14) is slit radially. The device includes a screw (32) that can be screwed through the threaded opening (26) so as to bear against the ring (14) and cause the ring (14) to bear with force against a portion of the inner edge (22) and tighten the ring (14) on the pin (20).
US08328853B2 Static compression device
A Static Compression Device (SC device) for active, measurable compression of a fusion graft by the surgeon at the time of surgery is disclosed. The SC device is attachable to adjacent vertebral bodies or other pieces of bone and has a device that applies compressive force to the adjacent vertebral bodies or pieces of bone to assist fusion according to Wolffs law. The SC device has a locking mechanism that maintains the compression applied at surgery, but prevents further compression (settling) from occurring after surgery. The SC device allows the surgeon the ability to compress a segment, measure the applied compression, and lock the segment in the compressed position. In one embodiment of the invention, the pressure is applied to the SC device through a compression device that applies a desired and measurable amount of force. In this embodiment, the combination of the SC device with a pressure applying and measuring device allows the surgeon more control over the force applied to a cervical, thoracic or lumbar implant than has previously been available. In the preferred embodiment, the SC device compresses two or more adjacent vertebrae across an adjacent bone graft to facilitate fusion of these vertebrae to treat pain produced by pressure from the disks between such vertebrae bulging and resulting in contact with and pressure on the spinal cord and adjacent nerve roots. In other embodiments, the SC device may be used to apply measurable compression across any type of bony interface (e.g. fractures) to facilitate union.
US08328841B2 Embolization coil delivery systems and methods
A system and method for ultrasonically guided endoscopic (EUS) delivery of one or more embolization coils to an internal body site. The embolization coil delivery devices are preferably ultrasonically guided to the selected internal body site after being advanced through the working channel of an endoscope with its distal end located near the selected internal body site. In one aspect, the system and method may be utilized to deploy an embolization coil into a lesion to promote thrombosis and/or prevent bleeding.
US08328838B2 Needle assembly for traditional oriental medicine
Provided is a needle assembly for use in oriental acupuncture. The needle assembly includes: a hollow tubular rod member; a pin member which is movably installed in the rod member and can be inserted into a person's skin; and a reuse preventing unit preventing the pin member, which is protruded from an end of the rod member and is inserted into the skin, from being protruded from the end of the rod member and inserted into the skin again.
US08328834B2 Ultrasonic device for cutting and coagulating
An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation, and fine dissection required in fine and delicate surgical procedures. The assembly includes a housing, a curved blade assembly and a first shroud and a second shroud.
US08328831B2 Water-jet device for separating a biological structure
The invention relates to a water-jet device. The aim of the invention is to improve the adaptation of one such water-jet device to different applications. To this end, the piston cylinder unit (2) is connected to the eccentric drive device (20) in a separable manner and is embodied as an application-specific set with the suction line (4), the pressure line (7), and the operating handpiece (3). According to the invention, the piston cylinder unit (2) is especially provided with an annular fixing region (25) in which the sealing element of the piston (17) plunges and loses tension in the drawn-out end position of the piston (17), and the membrane (26) has sufficient free space to move.
US08328821B2 Hair-removal appliance with different tool attachments
A hair removal appliance includes a hand-held part and interchangeable tool attachments. The hand-held part includes a housing on which various tool attachments are mountable, as well as a drive mechanism which is arranged in the housing and includes a driving element to which a respective tool attachment is adapted to be coupled with its attachment-side driving element. The tool attachments each have a coupling portion of identical construction and are connectable to a complementary coupling portion on the hand-held part of the hair removal appliance. Each of the tool attachments includes a driving element adapted to be coupled to a driving element on the side of the hand-held part.
US08328820B2 Device and method for fragmenting and removing concretions from body ducts and cavities
A medical device and method for breaking a concretion in a body into smaller pieces and removing the pieces from the body are described. The device has a dilator sheath, a lithotripsy probe, a tubular member, and a retrieval basket. The dilator sheath adapted to penetrate into a passage of the body to reach the location where the concretion is located. The lithotripsy probe is configured for shattering the concretion into smaller pieces. The tubular member is mounted within the dilator sheath adapted to permit the lithotripsy probe to be inserted into the tubular member. The retrieval basket is coupled to the tubular member, and configured for entrapping the concretion and the smaller pieces for their extraction from the body. The retrieval basket has a structure constituted by a plurality of filaments extending from a basket proximal end towards a basket distal end, and then returning to the proximal end after forming a plurality of filament loops in the basket distal portion, and a plurality of filament strands at the basket proximal portion.
US08328808B2 Minimally invasive orthopaedic apparatus and methods
Apparatus (20, 120, 300) and methods for use in the performance of minimally invasive orthopedic procedures, including apparatus and methods for use in the performance of such procedures under the visualization of an endoscope (22), are herein disclosed. Such procedures include a minimally invasive intramedullary nailing procedure, a minimally invasive bone graft harvesting procedure, a minimally invasive pelvic osteotomy procedure, an orthopedic implant revision procedure, and a minimally invasive percutaneous bone plating procedure.
US08328805B2 Percutaneous fixator and method of insertion
The present invention provides a technique for percutaneous intramedullary fixation. A protective outer sheath is provided for internal fixation of the proximal tibia. Additionally, a unique intramedullary plate is provided that is adapted for percutaneous insertion into the intramedullary canal of a long bone. A plate holder is also provided that may be utilized through the outer sheath to drive and position a fixation plate within the intramedullary canal.
US08328804B2 Suction coagulator
An electrosurgical suction coagulator is disclosed having improved thermal insulation between the active electrode and adjacent tissue. In embodiments, passive insulation is used to control the transfer of thermal energy from an electrosurgical electrode into surrounding tissue. Braided, closed-sell foam material, and open cell foam materials may be used to thermally insulate the outer surface of a suction coagulator shaft from an inner electrode. In embodiments, a suction coagulator shaft includes an external covering formed from open-cell foam material, which may be saturated with a coolant, such as water or saline, to increase the thermal mass of the shaft. In other embodiments, active cooling delivers coolant to the operative site. In yet other embodiments, a suction coagulator shaft includes a cooling jacket through which coolant is passed to actively cool the instrument. The improved electrosurgical suction coagulator disclosed herein may have a reduced operating surface temperatures which may result in reduced risk of undesirable effects to adjacent tissue, and may result in reduced operative times and improved patient outcomes.
US08328803B2 Polyp removal device and method of use
A device and system for removing tissue such as polyps is provided and includes a tubular member having proximal and distal ends, a snare portion operably extending from within the distal end of the tubular member and including first and second electrodes configured to treat tissue therebetween, the snare portion further including a cutting member for severing the treated tissue. The tissue removal device may further include a handle portion operatively extending from within the proximal end of the tubular member. The handle portion may be configured for operable engagement by a user and the cutting member may extend between distal ends of the first and second electrodes.
US08328800B2 Directive window ablation antenna with dielectric loading
An electrosurgical device for directing energy to a target volume of tissue includes a coaxial feedline having an inner conductor, an outer conductor coaxially disposed around the inner conductor, and a dielectric material disposed therebetween. An elongated electrically-conductive member is longitudinally disposed at a distal end of the inner conductor. A balun structure is disposed on the outer conductor. The device also includes an electrically-conductive cylinder coaxially disposed around a distal portion of the balun structure, and a dielectric structure disposed substantially adjacent to a distal end of the electrically-conductive cylinder, wherein the dielectric structure longitudinally extends from the distal end of the electrically-conductive cylinder to a distal end of the electrically-conductive member.
US08328796B2 Light energy delivery head
A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is applying light energy. In another aspect, various retroreflection configurations are provided which optimize retroreflection of back-scattered light energy from the medium. The size of the aperture through which light energy is applied to the medium is also controlled so as to provide a desired amplification coefficient as a result of retroreflection.
US08328794B2 System for electromagnetic radiation dermatology and head for use therewith
A system for treating a selected dermatological problem and a head. The head may include an optical waveguide having a first end to which EM radiation appropriate for treating the condition is applied. The waveguide also has a skin-contacting second end opposite the first end, which is in contact with the skin, and has a reflection aperture which is substantially as great as the radiation back-scatter aperture from the patient's skin. The portion of the back-scattered radiation entering the waveguide is substantially internally reflected therein, with a reflector being provided. The reflector may be angle dependent so as to more strongly reflect back scattered light more perpendicular to the skin surface than back scattered radiation more parallel to the skin surface. The head may also have a mechanism for forming a reflecting chamber under the waveguide and drawing a fold of skin therein.
US08328791B2 Selectively flexible catheter and method of use
Catheter assembly including an elongate shaft comprising a thermoplastic polymer such as a thermoplastic shape memory polymer having a pre-selected glass transition temperature (Tg) and a means for heating the thermoplastic polymer, wherein the thermoplastic polymer is in a rubbery state at temperatures above the glass transition temperature and is in a glassy state at temperatures below the glass transition temperature. The elongate shaft may be selectively heated and cooled to provide sufficient flexibility and retention during a medical procedure.
US08328790B2 Catheter tunneler
A tunneler (100,800) having a shaft (102,802) with an advancement end (106) and a connection end portion (104,804) having a lumen insertion tip (108,806) that may define a locating pin. At least one lumen-gripping section (120,818) is defined on the connection end portion spaced from the lumen insertion tip (108,806), and may be a barb section having at least one discrete barb (120), or an array of barbs (124), each with a sharp lumen-biting edge and a tapered lead-in surface (128) extending from the sharp edge toward the locating pin. Also, the lumen-gripping section (818) may be an annulus having a rounded lumen-engaging surface, or may be a circumferential array of nubs having rounded lumen-engaging surfaces. The connection end portion may have a plurality of axially spaced lumen-gripping sections (220,230;818) that may have the same diameters or different maximum dimensions for use with a range of sizes of catheter lumens.
US08328788B2 Methods and systems for electrokinetic delivery of a substance
A method for delivering a substance to an infected nail of an individual is described. The method includes the step of applying a device to at least one infected nail of an individual, where the device includes at least one active electrode and at least one counter electrode, where the at least one counter electrode is in contact with the individual, and where the device is connected to at least one power source. The method also includes the steps of disposing a medicament between the at least one active electrode and the at least one infected nail, applying a salt solution to the at least one infected nail, and providing an electrical current from the power source to the at least one active electrode to facilitate delivery of the medicament into the region of the at least one infected nail.
US08328787B2 Pain management methods and apparatus
A kit for charging an infusion pump having a reservoir for holding a local anesthetic. The kit includes a first stopcock having an input port, a first input/output port and a second output port and a manual control for selectively coupling either the first input/output port or the second output port to the input port. The kit further includes a second stopcock having an input port, first and second output ports and a manual control for selectively coupling either the first output port or the second output port to the input port. The second output port of the first stopcock is adapted for coupling to the input port of the second stopcock. The kit further includes a syringe adapted to be coupled to the first input/output port of the first stopcock and tubing for coupling the input port of the first stopcock to a source of the liquid and for coupling the output port of the second stopcock to an input port of the pump.
US08328785B2 Use of nanoparticles in the photodynamic treatment of tumors
A method for generating light intensity inside a tumor to aid in the treatment of diseases such as cancer is disclosed. The light is generated inside the body to perform a modified photodynamic therapy treatment (PDT) that allows treatment of body regions that are inaccessible by normal PDT procedures. In addition, the use of two spatially and temporally coincident treatment modalities, i.e. radiation and PDT, have the potential for significant biological synergy in the tumor.
US08328782B2 Hydrophobic surface coated light-weight nonwoven laminates for use in absorbent articles
The present invention relates to absorbent articles which include one or more barrier members comprising a light-weight nonwoven laminate that has been treated with a hydrophobic surface coating intended to render such components impermeable to liquids having relatively low surface tensions.
US08328780B2 Absorbent article with elastomeric bordered material
An absorbent article incorporates a material having a base layer of a generally fluid permeable material and at least two strips or regions of elastomeric material attached to the base layer material with a space therebetween such that a center region of the base layer material is bordered on at least two sides by composite regions of the elastomeric materials and the base layer material. The center region of base layer material remains generally non-elastic and the composite regions are stretchable in at least a first direction as a result of tensioning and necking-in the base layer material prior to attaching the elastomeric materials. The material may be incorporated as a bodyside liner in the absorbent article.
US08328778B2 Liquid collection system and related methods
Various embodiments of a fluid collection system having multiple storage chambers are disclosed. In an exemplary embodiment, the system may include a first chamber in fluid communication with a suction source and a second chamber in fluid communication with the first chamber. The second chamber may have a volume less than a volume of the first chamber. The second chamber may also comprise an inlet port for connecting to an external tube. The system may be configured to selectively drain liquid from the second chamber into the first chamber.
US08328777B2 Umbilical cord cell harvesting
An apparatus and method are provided for harvesting biological material from an umbilical cord. A drain functions to drain the material from the umbilical cord. The apparatus includes a seal member for sealing an open end of an umbilical cord with the drain. A support is provided to support the seal member. An actuator is provided to adjust the engagement of the seal member with the umbilical cord. Moving the actuator relative to the support allows the seal member to twist about the umbilical cord to seal against the umbilical cord to effect drainage of material from the umbilical cord to the drain without leakage.
US08328774B2 Vision corrective jig and cooling fluid injection tool for the jig
A jig and a cooling fluid injection tool are provided for use in the correction of corneal shape of an eyeball. Correction of the eyeball takes place while the cornea is warmed. The jig includes a shape retention part of a sucking disc configuration having an inner surface side that contacts the eyeball and a grip part formed on an outer surface side of the shape retention part. An inner surface-sided cornea contacting section of the shape retention part is flattened and a cooling fluid injection hole passing through the grip part is formed in the center of the shape retention part with a diameter large enough for a wearer to see outside.
US08328771B2 Method for fluid delivery and catheters for use with same
A pain management system for the infusion of drug to a wound site includes a pump connected to medical tubing which is connected to an improved infusion catheter for providing uniform delivery of fluid throughout an anatomical region. The infusion catheter is inserted into the body of a patient al a pierce site, spaced from an incision site, and extended to the wound site. The pump causes the drug to flow through the medical tubing, through the infusion catheter and to the wound site. In accordance with one embodiment of the catheter, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region.
US08328770B2 Disposable blood transfusion device
One embodiment of a blood transfusion device includes a drip chamber (10) comprising a bottom outlet (113); a filter (40) fixedly disposed in the drip chamber (10); and a float regulator (20) moveably disposed in the drip chamber (10) under the filter (40), the float regulator (20) comprising an inverted upper cup (21) including a top projection (212), a lower cup (22) secured to the upper cup (21), and a suction cup (23) secured to an underside of the lower cup (22). An inner diameter of the upper cup (21) is greater than an outer diameter of the lower cup (22). The projection (212) contacts an underside of the filter (40) when blood from a blood bag (90) sufficiently fills the drip chamber (10). The suction cup (23) falls to permanently close the outlet (113) when blood in the drip chamber (10) completely drains.
US08328768B2 Pressure activated safety valve with improved flow characteristics and durability
A valve assembly for vascular access, comprising a body defining a lumen adapted for flowing blood, the body including a luer housing for connection with a first blood conduit and a barb housing for connection with a second blood conduit and a plurality of slitted membranes disposed within the body portion, each of the slitted membranes generating a partial pressure drop for flow therethrough, each of the partial pressure drops being smaller than a total pressure drop for flow through the body portion.
US08328767B2 Disinfecting caps for medical male luer connectors
Caps can be used to cover and disinfect a male protrusion portion of a medical connector. Some caps can create a seal with the male protrusion to prevent antiseptic from entering a lumen the protrusion. A biasing element can aid in creating or maintaining the seal.
US08328756B2 Abdominal cavity balloon for preventing a patient's bleeding
An abdominal cavity balloon for preventing a haemorrhage in a patient's pelvic region, comprising an inflatable balloon, wherein the balloon is provided with a smooth surface and with a strip that is flexurally stiff and formed to follow the balloon's shape for positioning the balloon.
US08328753B2 Bioinjection device
The bioinjection device has a housing including a pistol grip and an elongated barrel. A trigger is pivotally mounted to the housing. A plunger and needle are slidable between a first position in which the plunger and needle are slidably disposed in the barrel and a second position in which the plunger and needle extend from an opening in the end of the barrel. A retaining member is disposed about the opening at the end of the barrel. A spring-biased actuation mechanism connects the trigger with the plunger and needle. A membranous cartridge containing bone morphogenic protein, antibiotics, and/or other medication is loaded into the retaining member. A surgeon can inject the cartridge into a bone fracture or degenerative bone tissue during surgery to deliver the medicament directly to the affected site.
US08328743B2 Dynamic hand splint
A dynamic splint for the positioning and functional exercise of a neurologically impaired upper extremity, including the wrist, hand and fingers, made up of a forearm support and hand support linked by a first connector. Fingertip caps are connected to finger tension leads that extend rearwardly to connect to a finger tensioner attached to the forearm support. The hand support includes adjustable tension lead guides for directing the finger tension leads to the fingertip caps. The dynamic splint also includes a thumb splint assembly made up of a thumb-tip cap connected to a thumb tension lead that extends rearwardly to a thumb tensioner attached to the forearm support. The thumb splint assembly further includes a thumb tension lead guide for directing the thumb tension lead to the thumb-tip cap.
US08328740B2 Spa machine with a pressure-balancing watertight electric control device
A SPA machine includes a housing provided with a water sprayer, a water pump mounted in the housing for pumping water out of the water sprayer, and a pressure-balancing watertight electric control device formed of a box, watertight buttons, an electric control unit, a watertight panel and a locating frame and mounted the housing for controlling the operation of the water pump and having a variable inside space automatically regulated subject to the external water pressure to prevent water penetration and to avoid electric leakage.
US08328738B2 Medical tool for reduced penetration force with feedback means
A medical device for reducing the force necessary to penetrate living being tissue using a variety of reciprocating motion actuators, including piezoelectric, voice coil, solenoids, pneumatics or fluidics. The reciprocating actuator drives a penetrating member, such as a needle, through the tissue at a reduced force while the device detects the passage of the penetrating member through the tissue. Upon passage of the penetrating member through the tissue, electrical power to the reciprocating actuator is automatically terminated. One exemplary method for detecting this passage is via a fluid-containing syringe that is coupled to a channel within the penetrating member. Once the penetrating member tip has passed through the living tissue, the fluid within the syringe no longer experiences any pressure and a plunger within the syringe displaces indicating passage of the penetrating member tip. This motion can provide direct tactile feedback to an operator of the medical device or can automatically open a switch providing electrical power to the medical device. Alternatively, a pressure transducer can also monitor the pressure within the penetrating member channel and automatically activate the switch to cut off the electrical power.
US08328734B2 Urine meter with improved drain construction
A urine meter is provided for use in a urine collection system. The urine meter includes a housing defining at least one fluid receptacle and having a concave upper wall having first and second ends and a central portion of reduced height. The housing defines first and second drain openings positioned adjacent respect ends of the upper wall. The housing also defines an inlet port extending through the central portion of the upper wall. A drain tube having a discharge end is positioned through the inlet port to direct fluid into the fluid receptacle. The drain tube has an internal surface having substantially no discontinuities. In one embodiment, the housing defines a centrally located first fluid receptacle and a second fluid receptacle which is positioned about the first fluid receptacle.
US08328731B2 Method and system for reconstructing the three-dimensional shape of the surface of at least a portion of an ear canal and/or of a concha
The method for reconstructing the three-dimensional shape of the surface (14) of at least a portion of an ear canal (18) and/or of a concha comprises—for each of a multitude of points (12) on said surface (14)—the step of using a chromatic coded distance measurement technique for determining a distance value (40) representative of a distance to said point (12); and further comprises the step of reconstructing said three-dimensional shape based on said multitude of distance values (40). The system for reconstructing the three-dimensional shape of the surface (14) of at least a portion of an ear canal (18) and/or of a concha, comprises a distance measurement unit for determining—by means of a chromatic coded distance measurement technique and for each of a multitude of points (12) on said surface (14)—a distance value (40) representative of a distance to said point; and a reconstructing unit (50) operationally connected to said distance measurement unit for reconstructing said three-dimensional shape based on said multitude of distance values (40).
US08328730B2 Living body measurement apparatus
A living body measurement apparatus according to the present invention functions both as a muscular tissue hardness tester for measuring hardness of muscular tissue of a living body and as an algesiometer for measuring a degree of sense of pain of the living body, and the apparatus includes: an contacting section which includes a first contact surface contacting the living body, and which applies pressure to the living body; an auxiliary section which includes a second contact surface contacting the living body, and which supports the second contact surface so that the second contact surface perform reciprocating movement between a coplanar position in which the second contact surface is disposed substantially coplanar with the first contact surface and a retracted position in which the second contact surface is retracted with respect to the first contact surface; and a locking mechanism which locks the auxiliary section in a state in which the second contact surface is disposed at the retracted position.
US08328727B2 Method and apparatus for assessing hemodynamic parameters within the circulatory system of a living subject
An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter by measuring a non-calibrated value of the parameter non-invasively, and inducing a stress of the circulatory system while measuring a second parameter. The response of the circulatory system to the stress is determined directly from the subject, and a calibration function is derived from the response and applied to the non-calibrated measured value to produce a calibrated measure of the actual value of the hemodynamic parameter. Methods of using backscattered acoustic energy for determination of hemodynamic markers are also disclosed.
US08328726B2 Method and apparatus for monitoring tissue ablation
Real-time monitoring of tissue ablation is possible by using a vibrating ablation needle coupling lateral shear waves to the tissue. Ultrasonic imaging may characterize the velocity of these shear waves to reveal Young's modulus of the tissue and, at a discontinuity in Young's modulus, a boundary of the ablated lesion reflecting an underlying increase in stiffness of ablated tissue. This technique may be coupled with quasi-static elastography-based ablation monitoring techniques for improved measurement.
US08328722B2 Method for aesthetically treating cellulite skin by lipotomy, and device for implementing said method
The invention relates to a method for aesthetically treating cellulite skin by lipotomy, and to a device for implementing said method.
US08328721B2 Ultrasonic determination of optical absorption coefficients
A system for the determination of optical coefficients in an object including an ultrasonic scanner for recording first and second pulse echoes before and after the object has been illuminated with a heating light beam from a light source. An evaluation unit determines a map of temperature increase caused by the heating light beam inside the object based on apparent displacements showing up between the second and first pulse echoes.
US08328716B2 Retracting cannula
A retracting two-piece cannula for distracting soft tissue from bone (e.g., the articular surface of a knee) to provide a surgical workspace for osteochondral repair. After inserting an outer cannula provided with a threaded outer surface into an incision (preferably widened by one or more dilators), the outer cannula is rotated to engage the threaded outer surface with the soft tissue to be distracted. An inner cannula is then inserted into the outer cannula and advanced until it contacts the articular surface. Further relative movement between the inner and outer cannulas causes the outer cannula to be drawn away from the articular surface, thereby retracting the soft tissue and establishing the workspace. The inner and outer cannula are then locked together to maintain the workspace, and an osteochondral core may be introduced through the inner cannula.
US08328711B2 Selectable multi-lumen brachytherapy devices and methods
A brachytherapy treatment device includes at least one tubular insertion member and an expandable member. The tubular insertion member has proximal and distal ends and at least one radiation source lumen disposed along its length and branching at the distal end to provide a plurality of selectable radiation source lumens each configured to receive a radiation source. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. In another embodiment, a brachytherapy treatment device may also include a plurality of selectable radiation source lumens forming an arcuate shape with respect to the longitudinal axis. Additional brachytherapy treatment devices and methods for performing brachytherapy and for forming an asymmetric radiation dosing profile are also disclosed.
US08328709B2 Fluid separator apparatus comprising a spin-up assembly
An apparatus for separating a fluid flow, the fluid flow comprising lighter and heavier fractions to be separated from each other, comprises a rotary centrifuge device (1), the lighter fractions being carried further on and the heavier fractions being carried through an outlet (5). The invention is characterized in that a spin-up assembly (17) is arranged upstream of the rotary centrifuge device (1), the spin-up assembly (17) being configured in such a manner that the fluid flow entering the rotating cylinder (1) is imparted a rotational movement, the rotational velocity of the cylinder (1) being adjustable so that the relative velocity difference between the rotating movement of the fluid flow and the rotational velocity of the centrifuge device (1) is optimal in terms of separation.
US08328700B2 Resistance apparatus for exercise devices
A resistance apparatus for use with exercise devices includes an axle and outer housing for rotatably mounting the axle therein. At least one inner housing includes an opening for receiving the axle therethrough so that the inner housing is fixably mounted on the axle. The inner housing is rotatably mounted inside the outer housing to permit rotation of the inner housing along with the axle within the outer housing. At least a first tensioned member is disposed within the inner housing. The first tensioned member includes a first end and a second end. The first end of the tensioned member engages an engagement area of the inner housing. The second end of the tensioned member engages an engagement area of the outer housing. The tensioned member creates a rotational restoring force between the inner housing and the outer housing.
US08328698B1 Exercise bar assembly for dual action weightlifting machine
A dual action weightlifting machine has a stationary frame including a racking portion and spaced vertical guides slidably mounted on opposite sides of the frame for horizontal movement relative to the frame. A horizontally extending exercise bar assembly has spaced first and second vertical slides slidably mounted on the vertical guides, at least one rotatable user engaging portion for gripping by a user, at least one rack engaging portion comprising a rotatable wear sleeve which rotates independently from the user engaging portion, and opposite first and second end portions for receiving one or more selected weights. The user engaging portion is located between the opposite sides of the frame and has a central longitudinal axis which is coaxial with the cylindrical surfaces of the wear sleeves.
US08328697B2 Device for changing load at any phase of movement
A device for varying a load applied to a vertical axis comprises a basic burden capable of vertical movement, a hinge with a horizontal axis, a lever having an end coupled to the hinge and capable of rotating around the horizontal axis, and a revolving means (a roller or pinion) for revolving about an axis mounted on the basic burden and extending essentially parallel to the horizontal axis, wherein the lever freely leans against the revolving means. In embodiments, the device may preferably comprise a supplemental burden secured in the region of the other end of lever. The lever may consist of two parallel rods fixedly attached to each other and pivotable around a common axis, or the rods can be independent, pivotable around the corresponding axis. The device provides convenient changing the load in the positive and negative phases of movement. It's usable in fitness, or for other purposes.
US08328696B2 Collapsible athletic training ladder
A collapsible ladder for use primarily for athletic training and the like has a plurality of spaced-apart, substantially rigid rungs secured with collapsible connectors to a plurality of spaced-apart, substantially rigid spacers extending therebetween. In one disclosed embodiment, the collapsible connectors are strips of flexible material extending between the rungs and spacers. Another disclosed embodiment has a second set of rungs aligned substantially parallel to the plurality of spaced-apart rungs along a common central set of spacers. The collapsible connectors allow the ladder to be quickly and easily transitioned between an extended, operational position, and a collapsed, storage position.
US08328694B2 Training method
A training method in which training coordinator device is in communication with a training transducer integrated in an exercise article. The training coordinator device receives training schedule data, for example, via an internet link, and uses this schedule to prompt and encourage a user in performing training activities in a real time and persistent manner defined in the training schedule by means of a user interface which may take the form of an LED array. The training coordinator device monitors training activities by signals from a suitably adapted training transducer, which may be integrated in an exercise article such as a bicycle etc. Information concerning the user's training activities may be published via an internet link for access by both the user and medical professionals, who may also be the source of the training schedule.
US08328689B2 Shift control method and system of automatic transmission
A shift control method of an automatic transmission controls a skip shift from a first shift-speed achieved by engagements of first and second frictional elements to a second shift-speed achieved by engagements of third and fourth frictional elements, wherein the engagements of the third and fourth frictional elements is controlled after completion of releases of the first and second frictional elements.
US08328688B2 Ratio shift control system and method for a multiple-ratio automatic transmission
A control system and method for controlling a multiple gear ratio automatic transmission in a powertrain for an automatic transmission having pressure activated friction torque elements to effect gear ratio upshifts. The friction torque elements are synchronously engaged and released during a torque phase of an upshift event as torque from a torque source is increased while allowing the off-going friction elements to slip, followed by an inertia phase during which torque from a torque source is modulated. A perceptible transmission output torque reduction during an upshift is avoided.
US08328683B2 Transmission assembly for electric vehicle
A transmission assembly for an electric vehicle includes a transmission having an input shaft, an output shaft, and a gear train coupled between the input shaft and the output shaft. A motor includes an output coupled to the input shaft of the transmission. A motor controller is electrically connected to the motor and controls a rotating speed of the motor. A gear controller is electrically connected to the motor controller. The gear controller outputs a speed request signal to the motor controller, and the motor controller controls the rotating speed of the motor based on the speed request signal, allowing smooth engagement between the gear train and the output shaft.
US08328682B2 System and method for controlling amount of time needed to commence transmitting engine torque in a vehicle
A method controls an amount of time required to commence transmitting torque of an internal combustion engine equipped with a stop/start feature to a transmission configured to transmit the torque of the engine to drive-wheels in a vehicle. The method includes determining whether a start of the engine is likely. The method also includes pre-filling with fluid a hydraulically-actuated clutch that is configured to connect the engine to the transmission when the start of the engine is likely. Accordingly, the amount of time required to commence transmitting torque of the engine to the transmission is reduced. A system employs the method for controlling an amount of time required to commence transmitting torque of the engine.
US08328680B2 Method for controlling the operation of a motor vehicle
A motor vehicle having a drive train and a motor unit which can be coupled to the drive train, and at least one electric machine. A freewheel mode is activated to increase the energy efficiency so that the motor vehicle is neither powered nor decelerated by the motor unit, thus allowing the wheels of the motor vehicle to essentially roll freely. In the freewheel mode, the electric machine is operated as a motor which introduces a freewheel mode pull torque to the drive train.
US08328679B2 Gear train of automatic transmission for vehicles
A gear train of an automatic transmission for vehicles is provided to improve power delivery performance and reduce fuel consumption as a consequence of realizing eight forward speeds and two reverse speeds by combining two simple planetary gear sets and one compound planetary gear set with two clutches and four brakes.
US08328676B2 Power split transmission
A power split transmission for a working machine, such as a wheel loader, having a continuously variable power branch and a mechanical power branch that are summed with one another via a summing gear (13). The summing gear (13) can be connected, via a clutch for forward drive (4) and a clutch for reverse drive (8), to an input drive. The power split transmission has shafts (2, 7; 32, 33) and only a single clutch is located on each shaft.
US08328675B2 Power pivot device for a plow
A pivot assembly for a plow may include first and second subassemblies. The first subassembly may be adapted to be coupled to a frame member and rotationally fixed relative thereto. The first subassembly may include a latch mechanism displaceable between locked and unlocked positions. The second subassembly may be adapted to be coupled to the frame member and may be rotatable relative thereto. The second subassembly may include a power pivot assembly and a cam member. The power pivot assembly may be drivingly engaged with the cam member and operable to rotate the cam member in a first rotational direction to a first position where the cam member urges the latch mechanism into the unlocked position.
US08328667B2 Magnetic expandable broadhead
Magnetic expandable broadhead arrowheads and methods for magnetically holding the blades of broadhead arrowheads in the retracted position are disclosed. Embodiments include deployable cutting blades that are magnetically held in a retracted position during launch and flight and deploy outwardly upon impact with a target. Other embodiments include magnets where the force holding the cutting blades in the retracted position is localized adjacent either the deployable ends or the pivoting ends of the cutting blades. Still other embodiments include magnets adjacent to substantially the entire length of elongated cutting blades while the blades are in the retracted position. Alternate embodiments include elongated cutting blades that extend in a rearward direction when retracted and cutting blades that extend in a forward direction when retracted.
US08328665B2 Combination pitching aid and batting tee
Described herein is a combination pitching aid and batting tee apparatus. The apparatus includes a base having a front and a rear, a stand extending upwardly from the base, a support rod extending upwardly from the stand, and an arm extending outwardly from the support rod. The arm includes a target associated therewith that can be adjusted vertically and horizontally. The apparatus includes a screen having a top end and a bottom end and a support assembly having a top end and a bottom end that extends upwardly from the base. The bottom end of the screen is attached near the front of the base and the top end of the screen is attached to the support assembly. The support rod can be replaced with a batting tee.
US08328661B1 Weighted golf club head
A golf club head having a center of gravity located at a point close to the face and the sole is disclosed herein. In particular, the golf club head comprises a hollow body including a weight lip and face component, and the weight lip extends from the sole inside the body into the face component. The golf club head is preferably a wood-type or hybrid-type golf club head.
US08328660B2 Muscle-back, with insert, iron type golf club head
A muscle-back iron golf club head includes a blade-like upper mass, a muscle-like lower mass, a planar front surface, a top surface, a sole surface, a heel surface, a toe surface, and a rear surface having a first contour. A recess is in the rear surface, the recess having a first portion in the blade-like upper mass and a second portion in the muscle-like lower mass. An insert may be provided in the recess, and such insert may substantially fill the recess and may include a back surface having a second contour which is different from the first contour of the club head rear surface.
US08328656B2 Golf club shaft with high balance point and golf club including same
A golf club shaft having a weight distribution such that the balance point percentage is less than or equal to 44.50%. The weight distribution of the shaft allows for an increase in length and/or club head weight of a golf club while having a reduced impact on the swing weight.
US08328655B1 Golf training tool
A golf training aid having an alignment rod rotatably mounted to an elongated rail. The rail is pointed directly at the target while the rod is rotated and positioned along the rail pointing directly to the ball.
US08328653B2 Object location and movement detection system and method
A system and method for detecting object location and movement utilizes a first viewing area (40) observed by a first camera (42) cooperating with a light (43) and a second camera (44) cooperating with a light (45). A third camera (46) can be added to observe a second viewing area (47) encompassing the first viewing area (40). The first camera (42) acquires images at time spaced points (51) and (53) along a first trajectory line (55). The second camera (44) acquires images at time spaced points (52) and (54) along a second trajectory line (56). This information is combined to generate the 3-D trajectory line (50) of the object.
US08328644B2 Asynchronous challenge gaming
Systems and methods to provide asynchronous challenge gaming are described. In some embodiments, a method presents multiple character actions to a first user and a second user of a game, where each of the character actions defines a game action to be performed by a character in the game. The method receives a selection from the first user and the second user that identify multiple character actions. Additionally, the method receives sequence assignments from the first user and the second user that define a sequential order for performing the character actions. The game play between the first user and the second user is displayed to the first user based on the character actions and the sequence assignments, and without further interaction with the first user or the second user subsequent to receiving the character actions and the sequence assignments.
US08328643B1 Crew creation for quest progression
Methods, systems, and computer programs for creating a crew to participate in a mission challenge in an online game are provided. The method identifies quests to complete the mission challenge. Each quest includes a plurality of tasks and each task includes a plurality of subtasks. A request feed is sent to members of a social graph requesting the members to join the crew and to participate in the completion of the subtasks of the mission challenge. The members in the social graph have a social relation with a user initiating the online game wherein the user is a mission leader managing the mission challenge. A distinct subtask is assigned to each member of the crew that responds to the request feed. Each crew member's progression in completing the mission challenge is monitored and status of the mission challenge is updated based on the progression made by each crew member of the crew.
US08328642B2 Game based incentives for commerce
The present disclosure generally relates to systems and methods directed to generating game-based incentives for users of online games to purchase goods in an electronic commerce system.
US08328641B2 Accounting system and method for casino game revenue
Systems and methods which provide real-time accounting for transactional exchanges involving credit or cash and gaming chips conducted between players and the casino at gaming tables.
US08328638B2 Method and apparatus for generating tactile feedback via relatively low-burden and/or zero burden telemetry
A method and a device for providing a tactile sensation are provided. The device includes a plurality of actuators. The plurality of actuators includes first and second actuators. The first actuator is adapted to provide a first tactile sensation, and the second actuator is adapted to provide a second tactile sensation.
US08328637B2 Combat action selection using situational awareness
A game environment is disclosed where actions are automatically selected based on a situational awareness for a player in the game environments. The situational awareness can be determined based on conditions of the player, objects and other characters in the game environment.
US08328630B2 Gaming award method and apparatus
A gaming system providing a tiered reward bonus promotion. A player's activity level is quantified to a value that adjusts over time. The value at the completion of a bonus period is compared to a plurality of tier values stored in memory at the central authority. Each tier value has an associated bonus award that is awarded to the player if the player reaches that tier at the completion of the bonus period. The award is indicated in the player's account and may be redeemed at a player kiosk.
US08328629B2 Reconciling payback percentage of a gaming device with transferable return
An electronic gaming machine (EGM) is configured to run a persistence game having one or more recordable persistence states transferable to another EGM. The EGM includes a logic system, a computer readable memory including instructions executable by the logic system for running on the EGM a persistence game having persistence states leading to a persistence award redeemable when persistence criteria are satisfied, each persistence state having a persistence value representing a portion of the persistence award, a verification interface configured for determining whether to initiate play of the persistence game at a previously recorded persistence state, a coin-in meter, a coin-out meter, and a theoretical coin-out meter storing in the memory unawarded persistence values accumulated by the machine from advancing the persistence game during game play among the one or more persistence states, and calculating a value for theoretical coin-out as a sum of the accumulated coin-out value and a difference between the persistence value of a current persistence state and the persistence value of a previous persistence state.
US08328628B2 Gaming system and a method of gaming
A gaming controller arranged to conduct a game having an overall return to player (RTP) and including a base game and a feature game. The gaming controller is arranged to conduct a base game and a feature game and includes an RTP controller arranged to operate in response to a player RTP instruction to configure a relative contribution of the base game and the feature game to the overall RTP.
US08328626B2 Wagering game with progressive game triggered by multiple players
A method of conducting a group wagering game that includes a special award that is attainable by players at a plurality of gaming machines. The method includes receiving wagers from players at the plurality of machines for playing individual wagering games. In response to a triggering condition that is associated with one of the machines, the group wagering game is presented including an opportunity to fulfill at least one of a plurality of victory conditions. In response to all of the plurality of victory conditions being fulfilled, the special award is awarded to the machine associated with a next triggering condition.
US08328625B1 Wagering game machine with a type driven interface
Systems and methods provide a type driven interface for a wagering game machine. One aspect of the systems and methods includes providing a game framework including a game library manager that manages creation, update and deletion of multiple wagering games on a gaming machine.
US08328624B2 Slot driven video story
A gaming system includes a network server connected to a plurality of gaming devices that are adapted to provide a video payout on each play based on a set of payout parameters. Memory at each gaming device stores payout parameters that correspond to each possible gaming result or outcome. When a play is initiated by a player, a gaming result is generated at a gaming device. The gaming device responds by accessing a corresponding payout parameter from the memory which may be a monetary amount, a video presentation segment or a combination thereof. If the payout is video, the network server receives the payout parameter and transmits video presentation segment to the gaming device accordingly. The gaming device then provides a video payout, in the form of displayed video presentation, to the player. The player thus receives at least one form of payment on each play.
US08328620B2 Hybrid gaming system
A hybrid gaming system comprising: an electronic gaming machine (EGM) comprising: a cabinet; a base game interface disposed within the cabinet and comprising a display and a base game player instruction input mechanism, a processor disposed within the cabinet and arranged to conduct a base game based on at least one player instruction received from the base game player instruction input mechanism; a feature game device mounted to the cabinet and comprising a feature game display mounted to the cabinet and a feature game instruction mechanism operable by the player to input at least one instruction; a trigger monitor arranged to determine that a trigger event has occurred such that a feature game is to be conducted; and a feature game controller located remotely from the EGM and responsive to the trigger monitor to generate feature data for at least one feature game to be displayed on the feature game display and to process the at least one instruction.
US08328614B2 Gaming system, gaming device and method for providing a wagering solitaire game
The present disclosure provides a method of determining suitable paytables for wagering Solitaire games or type games and a gaming system, gaming device and method for providing such wagering games with such paytables. In one embodiment, the paytable includes the outcomes in the form of ranges of the total numbers of cards which are banked at the time play terminates and the awards associated with each range. In various embodiments, the paytable is constructed such that certain of the awards increase non-linearly as the ranges of numbers of banked cards increase. In other words, in various embodiments, certain awards in the paytable have a different upper ratio to the number of cards banked than other awards in the paytable. In various embodiments, the Solitaire game includes one stage or multiple stages. The present disclosure also provides a paytable for multiple related plays of the Solitaire game.
US08328613B2 Game tower
A light source, a convex mirror and an optical sensor are disposed within a housing which is transparent to the range of wavelengths from the light source and of a low distortion scratch-resistant material. A game board is used with retro-reflective elements, such as moveable playing markers or game tokens, cards or regions affixed to and integrated into the game board. A data store stores the locations of the reflective elements and other game-related data, such as data needed to measure a player's score or position in a game or data to provide guided play. The convex mirror is disposed inside the housing such that light reflects from the light source, off the convex mirror, through the housing, and onto the game board.
US08328612B1 Methods and systems of enabling users to actively allocate advertising resources and promote follower tracking
The present invention provides a system that allows users to directly participate in advertising resource allocation decisions for advertisers and to actively cause navigation swarms to specific websites. Swarms of users can be enabled by playing a form of hide and seek, where users (hiders) actively hide at a specific network location (the place where a swarm is desired) and other users (seekers) then actively search for the hiding users, thereby creating a swarm effect toward a particular site or set of sites.
US08328611B2 Game program and game apparatus having objects that follow a line drawn by the player
A game apparatus has a touch panel for designating an arbitrary position within a screen on which a plurality of moving objects are arranged. A CPU repetitively detects the position designated via the touch panel, draws a line along the detected positions on the screen, every time that the detected position is in contact with any object within the screen, aligns the object on the line every time that the detected position is in contact with any object on the screen, moves the object aligned on the line to a trailing end direction of the line at a velocity V1 with the drawn line erasing from a leading end at a velocity V2 (>V1) and executes clearing processing in a case that an array of the objects on the line satisfies a matching condition with a goal condition array before the leading end of the line catches up with the object on the line.
US08328609B2 Ventilation assembly for the pressure relief of the interior of an automobile
A back-air blocking device to ventilate a motor vehicle's inside space includes a frame or housing made of a first plastic, and a valve flap, made of flexible material, connected in one zone to the frame and in other zones resting against a sealing surface of said frame when the flap is in its rest position. The flap detaches off the sealing surface when subjected to a pressure differential. The valve flap is a thin plate made of a closed-pore, foamed material.
US08328608B2 Air conditioner for vehicle
An air conditioner for a vehicle includes first and second fans driven and rotated by a driving source, and a case defining a first air introduction portion and a second air introduction portion from which at least one of inside air and outside air is introduced. The first fan and the second fan are arranged on a single common axis, and the first air introduction portion and the second air introduction portion are arranged at one side of the first and second fans. The case has therein a first air passage extending from the first air introduction portion to the first fan, and a second air passage extending from the second air introduction portion to the second fan, and the first air passage and the second air passage are provided to be partitioned from each other.
US08328607B2 Enhanced piccolo ducting with sidewall air outlets
A system for ventilating an aircraft cabin includes an air supply pipe connected to an air source, and a plurality of air distribution lines branching off from the air supply pipe. In a first operating state, the ventilating system is adapted to blow out the air, flowing through the air supply pipe, directly from the air distribution lines into the aircraft cabin. In contrast, in a second operating state of the ventilating system, at least some of the air distribution lines are connected to connecting lines which supply the air, flowing through the air supply pipe, to air outlets arranged in a distributed manner in the aircraft cabin.
US08328606B2 Aneroid replacement
An altitude switch limit assembly has two independent limit switches to monitor cabin pressure and back up performance of the auto and monitor channels on the aircraft. The auto channel closes a first switch upon sensing that a cabin pressure falls below a set value, the monitor channel closes a second switch upon sensing that the cabin pressure falls below the set value. A first independent limit switch may be wired to the auto channel and a second independent limit switch may be wired to the monitor channel. Logic circuitry may determine that the assembly closes an outflow valve regulating cabin pressure when either both independent limit switches sense the condition, or when one of the independent limit switch senses the condition and either the auto channel or monitor channel to which that independent limit switch may be wired senses the same condition.
US08328605B2 Passive systems and methods for shackling products
A passive system, apparatus, and method for transferring poultry products exiting the chiller to a cone or shackle line.
US08328604B2 Vacuum saw
A carcass processing system is provided. The carcass processing system includes housing, a splitting arrangement for splitting a carcass, elongate members attached to the housing for loosening unpalatable materials from the carcass, and vacuum suction ports coupled to the housing for collecting the loosened unpalatable materials.
US08328597B2 Nursing bra
The present invention provides a nursing bra having first and second breast cup members attached to a chest strap assembly. The strap assembly includes a primary band assembly for securing said nursing bra to a user's upper chest and a separate secondary band assembly coupled to each first and second breast cup. The separate secondary band assembly is configured and operable to provide slidable movement of each of the first and second breast cups relative to the primary band assembly for uncovering a breast during a nursing application.
US08328589B2 Contact
A contact of which the quality of crimping of a crimp portion can be easily and accurately determined. The crimp portion of the contact includes a bottom portion that supports conductors of electrical wires, and two side portions that are continuous with opposite sides of the bottom portion and are bent such that they hold the conductors therein. Three marks are formed in an outer surface of each side portion along a longitudinal direction of the contact.
US08328586B2 Actuating device for an electrical connection terminal
Actuating device for an electrical connection terminal, wherein the electrical connection terminal comprises a contact frame, arranged in a housing made of insulating material, with a conductor terminal connection for an electrical conductor, and the actuating device comprises an actuating element in the form of a pusher which is integrally connected to the housing made of insulating material, and wherein the conductor terminal connection is formed on the contact frame by at least one spring element, the free end of which forms a clamping edge which is directed toward the electrical conductor and to which a clamping force is applied, and the conductor terminal connection can be opened by action of the pusher on the at least one spring element by a force being applied to the spring element by the pusher counter to the clamping force. According to the invention, the pusher consists of a pusher arm, wherein the pusher arm is connected with one of its ends to the housing made of insulating material, and wherein the pusher arm extends along at least a partial section of two upper surfaces of the housing made of insulating material which are arranged at an angle to each other.
US08328582B1 Shortened adapter for light bulb sockets with miniature remote controller
A shortened adapter for a light bulb socket with highly overlapped male and female parts with an insulating hand-ring that extends only partially over the external surface of the adapter's female threading so it fits into the unthreaded collar of a light bulb socket, thereby significantly reducing the light bulb displacement. The shortened adapter can respond to an incoming signal and control the output of a light bulb. A reversible ring on the insulating hand-ring can change the adapter from being a dimmer to being an on-off control. A mechanism is disclosed to reversibly lock the adapter onto a light bulb. A miniature remote controller to work with the adapter is provided that has many advantages because of its very small size and compact shape. Further, one such controller can control several lights and several such controllers can control a single light in arbitrary combinations selected by the user.
US08328579B2 Shield case and connector having the same
The invention provides a shield case to cover a body, the body having a main body and first and second connecting portions projecting from the main body and lying adjacent to each other along a first direction. The shield case includes first to forth conductive shells. The first and second shells cover an outer circumference of the main body; the third shell covers the first connecting portion; and the fourth shell covers the second connecting portion. The third shell is in contact with at least one of the first and second shells. The first or fourth shell is in contact with the second shell. The fourth shell is provided integrally with the first shell and is adjacent to the third shell along the first direction. The first or fourth shell may not contact the second shell if the third shell is contactable with both the first and second shells.
US08328578B2 Electrical connector and a method for manufacturing same
An electrical connector assembly is provided and includes a plurality of cables, each of which have a conductor, and an electrical connector having a connector housing which houses a plurality of pins/sockets, each of which are connected to a pin/socket termination, wherein each pin/socket termination is connected to a conductor of the cables. The connector further includes a thermoplastic pre-mold covering which securely covers a portion of the connector housing, the pin/socket terminations and a portion of the plurality of cables, wherein the pre-mold covering is securely attached to the portion of the connector housing, the pin/socket terminations and the portion of the plurality of cables via a pre-mold process which incorporates a mold having a control finger configured to position the cables away from the wall of the mold cavity and flow channels for injecting plastic on both sides of the control finger during the molding process.
US08328577B1 Coaxial cable connector
A coaxial cable connector suitable for assembly with one of a series of coaxial cables having one same specification and different wire outer diameters is disclosed to use a plastic bushing for compressing by a barrel to wrap about the coaxial cable and compress an inner tube against the aluminum foil and insulation spacer of the coaxial cable, protecting the coaxial cable against weather and extending the lifespan, an O-ring in a locating groove around a front neck of a body shell or on an annular rear contact face of a screw nut to seal the gap between the screw nut and the body shell, and a curved spring plate for stoppage between an annular front stop face of the body shell and an annular rear contact face of the screw nut for grounding to enhance signal transmission reliability.
US08328558B2 Chinese / English vocabulary learning tool
In a method for teaching a vocabulary, a computer receives a user selection of a chapter from a plurality of chapters in a Chinese-English textbook, a user selection of a language in which to display questions in a user interface, wherein the language in which to display the questions is one of English, Simplified Chinese, Traditional Chinese, and Pin Yin, and a user selection of a language in which to receive answers to the questions in the user interface, wherein the language in which to receive the answers is another of the one of English, Simplified Chinese, Traditional Chinese, and Pin Yin. The computer determines a question including a vocabulary word in the chapter and in the language in which to display the questions. In response to receiving an answer to the question in the language in which to receive the answers, the computer determines if the answer is correct.
US08328555B2 Implant
An implant for anchoring a tightly fitting prosthesis includes an externally threaded implant body configured to be screwed into bone using an insertion tool, the body having a first end and a second apex end, said first end being provided with an internal open ended axial bore, the implant being tapered such that the apex end is smaller in diameter than the first end where the taper is not greater than 2°. The implant is also provided with an incremental cutting face.
US08328546B2 Auxiliary injection unit integrated in injection molding system
An auxiliary injection unit is disclosed that has an extruder barrel and extruder screw integrated within an injection molding system. The extruder barrel and extruder screw are contained within a mold plate of the injection molding system with a drive mechanism of the auxiliary injection unit being external thereof. A melt stream emanating from the extruder barrel of the auxiliary injection unit is in selective fluid communication with either a melt channel of a manifold providing melt thereto during an injection cycle or with a discharge channel of a melt discharge tube for purging melt. A melt diverter component receives the melt stream from the extruder barrel and includes a shuttle valve slidably positioned therein that is operated to selectively divert the melt stream produced by the auxiliary injection unit to either the melt channel of the manifold or the discharge channel of the discharge tube.
US08328541B2 Displacement conversion mechanism and actuator
A mechanism converts rotational displacement to linear displacement with ramped driver discoidal elements and ramped driven discoidal elements on a common central axis. The ramped surfaces of the two elements are complementarily shaped and opposed so that, when in contact and completely interengaged, they form an assembly of minimum length. The driver elements are rotated by an external force. The driven elements are allowed to translate along the common axis while being prevented from rotating about the common axis, whereby a rotational displacement of the driver elements by an externally applied force causes the elements to separate by camming action of the interengaged ramp surfaces to produce a linear displacement of the driven elements. A spring is coupled to the driven elements so as to restore the assembly to its minimum length in the absence of the externally applied force.
US08328539B2 Submersible pump motor protector
According to one or more aspects of the present disclosure, a motor protector comprises a housing defining a compensator chamber; a compensator disposed in the housing having a motor fluid end in fluid communication with a motor fluid and a well fluid end, the compensator axially moveable relative to the housing in response to the expansion and contraction of the motor fluid; and a port formed through the housing to provide fluid communication from exterior of the housing to the well fluid end of the compensator. The compensator may be one selected from the group of a bellows and a plunger.
US08328537B2 Pumping unit for enteral or parenteral nutrition or perfusion
A single-use pumping casing (A) includes an inlet duct (6), a delivery duct (7) and a alternating-movement pumping member (1a), and a driving mechanism including a member (4) for driving the pumping member (1a) in at least one of the alternating movements thereof. The driving mechanism is housed in a holder housing (B) having a wall with a retaining slideway (19) for engaging sliding members of the pumping casing (A), the housing further including a passage opening (21) for the driving member (4), an abutment (20) for determining the position of the pumping casing (A) along the retaining slideway (19) and for placing the pumping member (1a) into a drive relation with the driving member (4), and a removable attachment (19, 20) for attaching the pumping casing (A) in the determined position along the retaining slideway (19).
US08328536B2 Cranked rod pump apparatus
An improved apparatus and method are provided, for pumping fluids, such as water and/or hydrocarbons, from a subterranean formation or reservoir, through use of a cranked rod pumping (CRP) apparatus for imparting reciprocating substantially vertical motion to a rod of a sucker-rod pump having a pump stroke. The CRP apparatus includes a motor driven cranked mechanical actuator arrangement. The cranked mechanical actuator arrangement includes a substantially vertically moveable member attached to the rod of the sucker-rod pump for imparting and controlling vertical motion of the rod of the sucker-rod pump. The actuator arrangement may include pneumatic counterbalancing.
US08328532B2 Compressor muffler
A compressor has first and second enmeshed rotors rotating about first and second axes to pump refrigerant to a discharge plenum. The compressor includes a muffler system comprising a sound absorbing first element and a sound absorbing second element. The second element at least partially surrounds the first element and defines a generally annular flow path portion between the first element and the second element At least one of the first and second elements comprises an expanded bead material.
US08328526B2 Vacuum conveyance system
It is an object of the present invention to provide a portable vacuum carrying system comprising an ion pump (6) comprising a casing (1), a positive electrode (2) provided in the casing (1), a negative electrode (3) fixed to the inner wall of the casing (1) and located on the circumference of the positive electrode (2), magnets (4) placed so as to surround the circumference of the negative electrode (3), and a connection part (5) for connecting the casing (1) to other devices.
US08328525B2 Electric compressor and control device for estimating compressor discharge temperature
An inverter-integrated electric compressor has a control device. The control device estimates a compressor suction pressure based on the temperature of the power element of the inverter, or directly measures the compressor suction pressure by a sensor, or estimates the compressor suction pressure based on a compressor suction temperature or on a compressor housing temperature. Further, the control device calculates a motor torque based on a motor rotational speed, a motor phase current, and a motor phase voltage, estimates a compressor discharge pressure based on the compressor suction pressure and the motor torque, and estimates a compressor discharge temperature based on the compressor suction pressure and the compressor discharge pressure. The electric compressor has a discharge temperature detection device in place of a conventional thermal protector.
US08328523B2 Synchronous torque balance in multiple pump systems
The present invention provides a new and unique method and apparatus for operating and running multiple pumps in a system together at a substantially synchronous torque to achieve a desired setpoint. Each of the multiple pumps may be operated with a variable speed drive. The present invention may also take the form of the system having the multiple pumps with a system controller for operating and running the multiple pumps, a pump for operating and running in such a system, a system control module for such a system controller, as well as a pump control module for running and operating such a pump.
US08328519B2 Rotor with improved balancing features
A rotor assembly for a gas turbine engine including a circumferential array of regularly spaced apart features provided on the disk which are each configured for receiving a balancing weight. The circumferential array of features has an angular orientation relative to the circumferential array of blades such that the features are each located at an at least substantially same offset angle from a stacking line of a respective adjacent blade.
US08328518B2 Turbine vane for a gas turbine engine having serpentine cooling channels
A turbine vane for a gas turbine engine having an internal cooling system formed from at least one serpentine cooling channel with enhanced cooling elements. The serpentine cooling channel may include a first turn manifold with purge air discharge orifices inline with a first pass of the serpentine cooling channel. Cooling fluids may be used to cooling the leading edge of the vane and passed through the purge air discharge orifices to purge the rim cavity proximate to the endwall. The first turn manifold may also include a plurality of trip strips. The trips strips may be positioned on the suction and pressure sidewalls and may be offset from trip strips on the opposing sidewall. The cooling system may also include an aft purge rim orifice.
US08328517B2 Turbine airfoil cooling system with diffusion film cooling hole
A cooling system for a turbine airfoil of a turbine engine having at least one diffusion film cooling hole positioned in an outer wall defining the turbine airfoil is disclosed. The diffusion film cooling hole includes a first section extending from an inner surface of the outer wall into the outer wall, a second section extending the first section toward an outer wall, and a third section extending from the second section and terminating at an outer surface of the outer wall. The diffusion film cooling hole may provide a metering capability together with diffusion sections that provide a larger film cooling hole breakout and footprint, which create better film coverage and yield better cooling of the turbine airfoil. The diffusion film cooling hole may provide a smooth transition, which allows the film cooling flow to diffuse better in the second and third sections of the diffusion film cooling hole.
US08328516B2 Systems and methods of assembling a rotor blade extension for use in a wind turbine
A method of assembling a blade extension assembly for use with a wind turbine. The method includes removing a tip end of a tip portion of a rotor blade and coupling a tip wall to the tip portion. The tip wall extends between a first sidewall and a second sidewall and includes a plurality of slots defined therein. A blade extension assembly is coupled to the tip portion.
US08328510B2 Sealing device for rotary fluid machine, and rotary fluid machine
A sealing device includes a housing that rotatably accommodates a rotary shaft, a plurality of guide parts that extend along at least one of a radial direction and an axial direction of the rotary shaft and that impart flow velocity components in the rotation direction of the rotary shaft to fluid passing through therebetween, a partition part that connects ends of the plurality of guide parts and that serves as a partition between spaces between the plurality of guide parts and an outside space, a first seal part that is an annular protrusion extending in the radial direction, that forms a first gap with respect to the rotary shaft or the housing, and that blocks fluid flowing toward the plurality of guide parts, and a second seal part that is an annular protrusion, that forms a second gap with respect to the rotary shaft or the partition part, and that blocks fluid flowing through the outside space.
US08328509B2 Turbomachine
A turbomachine comprises a housing (71) defining a bearing cavity (71) and a turbine chamber (77a) separated by a first wall. A heat shield (72) is disposed between the first wall and the turbine wheel (77), a heat shield cavity (78) being defined between the first wall and the heat shield (72). The shaft (81) extends through a passage (85) defined at least in part by a first aperture (86) in said wall and a second aperture (87) in the heat shield (72). A first seal (88) is provided between the shaft (81) and said first aperture (86). The housing defines a first gas channel (79) communicating with the heat shield cavity (78) for connection to a pressure source for raising pressure within the heat shield cavity (78). A second channel (92) is provided between the heat shield cavity (78) and said passage (85), the second channel opening to said passage (85) on the opposite side of said first seal (88) to said bearing assembly (82). A second seal (89) is provided between the shaft (81) and said second aperture (87).
US08328504B2 Aeroengine drain assembly
A gas turbine engine has a nacelle, a plurality of pipes and a drains assembly, the drains assembly including a drains mast that extends through the nacelle and provides an outlet for the pipes. The engine is characterised in that drains assembly has a connection block defining internal passages and is arranged to connect between the pipes and the drains mast. The connection block also has lateral connections to the pipes enabling the nacelle to have a lower profile; thereby reducing aerodynamic drag.
US08328502B2 Torque converter having stator with cast-in side plate
A method for manufacturing a torque converter includes providing an outer race of a one way clutch, contacting the outer race with a side plate, and casting a stator housing together with the outer race and the side plate. A torque converter is also provided.
US08328501B2 Fan intake shield
A power tool includes a housing having an intake aperture, a fan disposed within the housing and operable to draw air through the intake aperture, and a fan intake shield positioned adjacent the intake aperture. The fan intake shield includes a first rib, a second rib adjacent the first rib and spaced from the first rib to define an air flow path into the intake aperture between the first rib and the second rib, and a third rib adjacent the first rib and spaced from the first rib to define an air flow path into the intake aperture between the first rib and the third rib. Each of the first, the second, and the third ribs has a respective height, and the height of the first rib is greater than the height of the second rib and the height of the third rib.
US08328500B2 System for controlling variable-geometry equipments of a turbomachine, particularly by articulated bellcranks
A system for controlling at least two variable-geometry equipments of a turbomachine, in which the first equipment is a variable pitch stator blade stage of a compressor of a first core moving between a closed position at idle speed and an open position at high speed, and the second equipment is at least one bleed valve of a compressor of a second core moving between an open position at idle speed and a closed position at high speed, is disclosed. The actuator operates over a portion of its travel a first branch of an angle transmission member which actuates the first equipment and leaves this branch at rest on an abutment over the rest of its travel. The actuator operates the second equipment via a sliding junction member arranging a free travel in the actuation of said second equipment.
US08328499B2 Road with inlayed wind harnessing technology
A method and apparatus is provided for harnessing the wind energy generated by vehicles passing on a roadway. A roadway is provided with a trench extending from a surface of the roadway. The trench may be provided along an extended stretch of the roadway or as a discrete trench section spaced apart along the roadway. The trench or trench section may be provided near the middle of a lane making up the roadway such that a vehicle travelling on the roadway passes over the trench. In this manner the wind displaced by the passing vehicle is directed into the trench and experienced by a wind turbine or wind generator provided within the trench. The trench is covered by a structure configured to direct the displaced wind inside the trench. The wind turbine converts the kinetic energy of the wind into mechanical energy that is then converted into useable power.
US08328498B2 Component feeding unit and method, and component mounting apparatus and method
In stacking tray supplying for receiving in a stacked state a plurality of trays that are received in a state in which components to be mounted onto a board are aligned, two tray stages are provided rotationally transferably on a concentric circle. In a state in which one is positioned in a feeding tray placement position and the other is positioned in a standby tray placement position, components are fed from the tray stage positioned in the feeding tray placement position. When a component depletion state occurs, the tray stages are rotationally transferred to switchover the mutual placement positions, by which waste of time required to feed components is reduced.
US08328496B2 Silo unloader
A bottom unloader for conveying feed material from a silo is disclosed. The unloader may have a housing with a drive unit and discharge, a conveyor positioned in the trough of a silo and a rotating cutter arm. The bottom unloader may be equipped with heavy-duty hooks having a wide uniform forward profile to prevent breaking and clogging of the conveyor. The hooks may be arranged in a repeating sequence to optimize unloading. The silo trough may have a wide chamfered section to prevent bridging. A discharge cover may extend from the conveyor to cover the top of the trough within the silo. The discharge cover remains fixed to conveyor backbone and is removed from the silo with conveyor.
US08328495B2 Reduced capacity carrier, transport, load port, buffer system
A semiconductor workpiece processing system having at least one processing apparatus for processing workpieces, a primary transport system, a secondary transport system and one or more interfaces between first transport system and second transport system. The primary and secondary transport systems each have one or more sections of substantially constant velocity and in queue sections communicating with the constant velocity sections.
US08328494B2 In vacuum optical wafer heater for cryogenic processing
A vacuum assembly used for warming processed substrates above the dew point to prevent unwanted moisture on the processed substrate surfaces as well as reducing negative impact on manufacturing throughput. The vacuum assembly includes a processing chamber, a substrate handling robot, and a heater which may be an optical heater. The processing chamber is configured to cryogenically process one or more substrates. The transfer chamber is connected to the processing chamber and houses the substrate handling robot. The substrate handling robot is configured to displace one or more substrates from the processing chamber to the transfer chamber. The heater is connected to the transfer chamber above the substrate handling robot such that the heater emits energy incident on the substrate when the substrate handling robot displaces the substrate in the transfer chamber.
US08328488B2 Stud retainer apparatus
A connector assembly configured to secure at least one component to a structure may include a base, at least one member configured to receive and retain a portion of a component, and a stud retainer extending from the base. The stud retainer may include first and second engaging legs within a retaining chamber. The first and second engaging legs are configured to automatically align the stud retainer with respect to a stud that passes into the retaining chamber.
US08328487B2 Mechanical assembly retention element
The present invention is directed to a retention element for retaining first and second components in assembled relationship. The first component comprises a body having first and second external surfaces and an inner wall defining an aperture extending through the body, and the second component comprises a longitudinal member having a size and configuration to permit insertion within said aperture to thereby assemble the components. The retention element comprises: an elastromeric protuberance extending into the aperture from a base adhering to the inner wall to a distal edge which spans a portion of the aperture. The protuberance also has an inside wall and an outside wall which meet at the distal edge and together define a flexible free end. Upon insertion of the second component into the aperture of the first component, the free end of the protuberance flexes in the direction of insertion such that the force required to assemble the two components is less than the force required to disassemble the two components.
US08328482B2 Hydraulic foundation bolt tensioner
A tensioner for tensioning foundation bolts generally used in securing large utility towers is provided. The tensioner generally comprises a hollow outer body through which the foundation bolt can extend. The lower end of the body, which is adapted to abut onto the foundation surface from which the bolt extends, is provided with an opening allowing access to a foundation nut threaded onto the foundation bolt. The upper end of the outer body slidingly receives therein an inner body with which it defines an annular hydraulic piston, the inner body being configured with a seat portion for receiving and engaging a split nut mounted to the foundation bolt. Upon providing hydraulic fluid to the tensioner, the hydraulic piston urges the split nut, engaged to the foundation bolt, upwardly, thereby tensioning the foundation bolt. The load in the bolt is then maintained by threading down the foundation nut until it abuts onto the foundation surface.
US08328478B2 Gantry pallet
The gantry pallet and allweather cover described includes, in its preferred embodiment, many improvements over the currently applied methods of storing, transporting and shipping the U.S. Navy's steam tube Gantry Cranes and accompanying appurtenances. Further included are lifting plates for safely lifting and/or handling and/or safely transporting the gantry pallet and allweather cover by a variety of methods. Another improvement is a provision for ridged, moisture barrier, non-corrosive cover that attaches to and seals against the gantry pallet frame. Another improvement involves a provision for on and off loading that allows substantial improvement in the speed of set-up and the safety in which, but not limited to, the U.S. Navy steam tube Gantry Cranes and accompanying appurtenances is applied to an aircraft carrier's catapult steam tubes. This invention will reduce the man hours needed to set-up, remove and install an aircraft carriers catapults steam tubes while protecting the gantry crane from the elements thus prolonging the life of the gantry crane and accompanying appurtenances.
US08328475B2 Cutting tool assembly including a release mechanism
An arbor assembly for connecting a cutting tool to a power tool includes a shaft defining a longitudinal axis and having an end portion configured to couple to the cutting tool, and a plate surrounding a portion of the shaft adjacent to the end portion. The plate has a first surface configured to engage the cutting tool when the cutting tool is coupled to the shaft and a second surface substantially opposite the first surface. The plate is movable along the longitudinal axis relative to the shaft. The arbor assembly also includes a wedge member positioned adjacent to the second surface of the plate and defining an opening to receive a portion of the shaft. The wedge member is movable relative to the plate from a first position, in which the plate is inhibited from moving along the longitudinal axis away from the end portion, to a second position, in which the plate is movable along the longitudinal axis away from the end portion.
US08328473B2 Drill and method of producing printed circuit board
A drill in which no positional shift on a drilled hole and no irregularities on an internal wall are formed. A torsion angle of a shaving discharge groove of a drill is set in the range of 30 degrees to 50 degrees. In this manner, a positional shift of a through hole to be drilled can be reduced. In addition, shavings of the drill are properly discharged, and thus, drilling is not precluded by the shavings. Therefore, a printed wiring board having excellent electric connectivity and reliability can be obtained.
US08328470B2 Apparatus and method for ground improvement
An apparatus and method for ground improvement includes a device having a plurality of tines extending downwardly from a top plate in a manner to achieve displacement of ground material downward and radially outward. The device is mechanically driven into the ground to achieve predetermined depths of penetration by the tines. The device is retracted and driven repeatedly to achieve densification. Optionally, voids made by the device can be filled with a flowable media.
US08328467B2 Powered sheave for node deployment and retrieval
A method and apparatus for deploying a plurality of seismic sensor units into a water column is provided. In one embodiment, a marine vessel is provided. The marine vessel includes a node storage and handling system disposed on a deck of the vessel. The node storage and handling system comprises a cable handler positioned adjacent a workstation proximate to a stern of the vessel, a node storage rack positioned between a bow and the stern of the vessel, the workstation being substantially parallel to a length of the node storage rack, and at least a first conveyor and a second conveyor positioned between the node storage rack and the workstation, wherein one of the first conveyor or the second conveyor is vertically movable relative to the node storage rack.
US08328465B2 Offshore petroleum discharge system
A method and associated vessel for transferring liquids from offshore tankers to an onshore storage facility. The system utilizes a flexible pipe that is heavier than the water it displaces, such that the flexible pipe sinks to the sea floor even when empty. The high weight and relatively small profile of the flexible pipe avoids the need for anchoring the pipe to the sea floor. The flexible pipe has a bending radius of no greater than five feet, such that it can be wound onto spools onboard the vessel, and can be rapidly deployed, retrieved, and reused in another location. The vessel containing the spools of flexible pipe is dynamic positioning capable, and contains the equipment required to establish a position onshore to receive the liquid being transferred; means to deploy, retrieve, and repair the flexible pipe; and means to receive liquid from a tanker vessel and pump that liquid through the flexible pipe to the onshore storage facility.
US08328463B2 Reflective road marker
An embedded-type reflective road marker (1) which includes a base (2) and a reflector (3) for reflecting light cast onto the marker. The reflector (1) is detachably connected or secured, in use, to the base (2) by a connector (4) having release means (40) for facilitating removal of the reflector (3) from the base (2).
US08328459B2 Coupler for excavators
A coupler for an excavator, the coupler comprising first and second recesses for receiving the pins of an attachment, a latching hook movable into and out of a latching state in which it closes the second pin-receiving recess, and a blocking bar movable into and out of a blocking state in which a portion of the blocking bar closes the first recess. The arrangement is such that, when the blocking bar is engaged in use by an attachment pin contained within the first recess, the action of the pin on the blocking bar urges the blocking bar into its blocking state. The blocking bar is further arranged so that, in the blocking state, it lies in the path of the latching hook and that, upon movement of the latching hook out of the latching state, the latching hook engages with the blocking bar to retain it in the blocking state.
US08328456B2 Fastening system for fixing and/or aligning at least one sensor element
A fastening system for fixing and/or aligning at least one sensor element, in particular an active infrared sensor or the accessory parts thereof, such as printed circuit boards, controls, energy sources etc., in a rail element with at least one fastening element, characterized in that the fastening element can be plugged from a front side into the rail element at any desired position. The object is further achieved by providing a fastening system for fixing and/or aligning at least one sensor element, in particular an active infrared sensor or the accessory parts thereof, such as printed circuit boards, controls, energy sources etc., in a rail element with at least one fastening element, characterized in that at least one sensor element and/or the accessory part thereof can be inserted into at least one fastening element in a fashion capable of being re-released and of being aligned with regard to its inclination and the like.
US08328454B2 Vertically adjustable bicycle assembly
An adjustable assembly for a bicycle includes a first support having an interior surface and a second support slidably positioned within at least a portion of the first support. One of the first support and the second support is adapted to attach to a first bicycle portion, and the other of the first support and the second support is adapted to attach to a second bicycle portion. Further, the second support comprises an expansion portion configured to be moved between an expanded position and a retracted position. The expansion portion is configured to engage the interior surface of the first support when the expansion portion is in an expanded position. In addition, the first support is configured to be selectively moved relative to the second support when the expansion portion is permitted to assume a retracted position. In some embodiments, the first bicycle portion comprises a bicycle frame and the second bicycle portion comprises a bicycle saddle. In other arrangements, the first bicycle portion comprises a fork assembly and the second bicycle portion comprises a handlebar assembly.
US08328451B1 Dehydrated dentifrice and toothbrush
A toothbrush has one or two part-spherical pockets formed in the brush surface. Balls or pellets of matching shape of dehydrated toothpaste are placed in the depressions, the brush is wetted and the pellets turn to a gel, ready for brushing. The pellets may be of various colors and flavors to entice children to brush their teeth and may be dispensed from a storage chamber carried in the tooth brush handle.
US08328449B2 Click pen applicator device and method of using same
A click pen applicator device that provides predetermined dosing of the formulation for precise application, and rapidly primes the formulation using the dosing click mechanism to prepare the applicator for use.
US08328448B1 Hardware hole filling device
A hardware hole filling device featuring a tube having an inner cavity for holding a filling; a tip disposed on the first end of the tube; a tip nozzle removably attached to the tip of the tube; a removably screw cap for covering the tip nozzle; and a riser mechanism functioning to push the filling from the inner cavity of the tube to the tip nozzle, the riser mechanism involves a threaded riser shaft, a riser threaded on the riser shaft, and a shaft base, the riser shaft can be moved in a first direction and a second direction by twisting the shaft base causing the riser to moved upwardly and downwardly, respectively, on the riser shaft, when the riser is moved upwardly the filling in the inner cavity of the tube is pushed to the tip nozzle.
US08328447B2 Containers for pushing out applying material
When rotating a main body tube and an operation tube in a disclosed container toward a first direction, a moveable screw tube advances a predetermined amount. When further rotating toward the first direction, a screwing part urges a moving body forward. A female thread of the screwing part in the moveable screw tube is radially outwardly expandable via a slit. When the moveable screw tube advances toward the first direction, the outer diameter of the front end part is restricted and expansion thereof is prevented. When further rotating toward the first direction and the screwing part urges the moving body forward, expansion of the front end part and the female thread of the screwing part may be suppressed. Accordingly, the screwing part reliably exerts screw function when the moving body advances.
US08328441B2 Tape drive and printing apparatus
A tape drive for use in for example a transfer printing apparatus to drive a printer ribbon. The printer ribbon is mounted on two spools each of which is driven by a respective stepper motor. A controller controls the energization of the motor such that the ribbon is transported in at least one direction between spools mounted on the spool support. The controller is operative to energize both motors to drive the spools of ribbon in the direction of ribbon transport to achieve push-pull operations. Ribbon tension is monitored to enable accurate control of ribbon supply and ribbon take-up, the ribbon tension being monitored, for example, by monitoring power supply to the two stepper motors.
US08328439B2 Electronic dampening for a camera crane
A camera platform may be stabilized by reducing or avoiding oscillating movement, when active stabilization systems are not used. A passive dampener resists the back driving of the motors used in the active stabilization system. This dampening or resistance to back driving the motors in turn dampens movement of the camera platform. Oscillations are reduced or avoided and the camera platform may return more quickly and smoothly to a level position. The dampener may be provided as an add-on or temporarily electrically switched in accessory. The dampener may include a circuit that connects the first and second motors of the active stabilization system in series, and connects the series output of the two motors to a variable resistor through a rectifier. A transistor may be with the variable resistor to provide for more linear adjusting and a more compact variable resistor.
US08328436B2 Optical module
An optical module includes a receptacle for receiving an optical connector attached to a distal end of an optical fiber, and a lens body having a contact surface coming into contact with the distal end of the optical fiber when the receptacle receives the optical connector. The lens body has the contact surface and an opposing surface opposing the contact surface, and further has a columnar base held by the receptacle, a lens portion formed on the opposing surface integrally with the base, and a flat portion. The lens portion is surrounded by the flat portion and is off-centered with respect to the base.
US08328434B2 Universal serial bus (USB) connector having an optical-to-electical/electrical-to-optical conversion module (OE module) and high-speed electrical connections integrated therein
A USB connector is provided that has an OE module and high-speed electrical connections integrated therein. The OE module includes an optical module, at least one laser diode, at least one photodiode, an optical transceiver IC, and a PCB. The optical module, the laser diode, the photodiode, and the IC are mounted on a surface of the PCB. The OE module is secured within the USB connector. The PCB includes conductive traces and electrical contact pads. The conductive traces electrically connect the IC with the contact pads. The contact pads are electrically connected via through holes formed in the PCB to the high-speed electrical connections, which, in turn, are electrically connected to conductive traces of a motherboard or a computer.
US08328432B2 Fiber optic cable assembly
A fiber optic cable assembly includes a fiber optic connector and a fiber optic cable having at least one strength element, the connector and cable held together by a crimp band. The crimp band may include at least one lateral aperture on at least one end for inspecting the disposition of the strength element prior to crimping to ensure a uniform distribution of the strength element.
US08328430B2 Thrust roller bearing
A thrust roller bearing 10 is provided in which one half of total gap which results from adding up an outer diameter side in-bearing gap 22 and an inner diameter side in-bearing gap 23 in diametrical direction is made larger than the amount of eccentricity between a member 51 which supports an outer ring 11 and a member 53 which supports an inner ring 14. When inside diameter at distal end of an outer locking portion 19 along a distal edge portion of an outer flange 13 is φD1, outside diameter of a cage 18 is φD2, outside diameter at a distal end of an inner locking portion 20 along a distal edge portion of an inner flange 16 is φD3, inside diameter of the cage 18 is φD4 and thickness of the cage 18 is t, A, B are defined as A=(D2−D1)/t and B=(D3−D4)/t, 0.1≦A, B≦5 is satisfied.
US08328425B2 Split-type sliding bearing for a crankshaft in internal combustion engine and split-type sliding device
A split-type sliding bearing for a crankshaft in an internal combustion engine fits within a bearing housing having a housing half with a higher thermal expansion coefficient, and a housing half with a lower thermal expansion coefficient. The pair of semi-cylindrical bearings includes first and second semi-cylindrical bearings, the first being supported on the housing half having a higher thermal expansion coefficient, and the second being supported on the housing half having a lower thermal expansion coefficient. The first and second semi-cylindrical bearings have equal outer diameter, and the first has circumferential ends having a thickness smaller than that of the opposite circumferential ends of the second semi-cylindrical bearing.